HRTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $0.35
Market Cap $65M
P/E (TTM) -1.9
EPS (TTM) $-0.18
Revenue (TTM) $151M
ROE (TTM) 334.6%
52W Range $0–$2

HRTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

Stock splits 2
Ex-date Split Type
Jan. 13, 2014 1-for-20 Reverse
May 25, 2007 1-for-4 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$155M
2016-12-31 → 2025-12-31
EPS$-0.12
2021-12-31 → 2025-12-31
Free Cash Flow$-28M
2016-12-31 → 2025-12-31
Net margin-22.5%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend HRTX 5Y avg Peer Median Verdict
P/E (TTM) -1.95Y avg ≈-7.1 ≈-7.1 · ·
P/S 0.45Y avg ≈3.8 ≈3.8 186.1 Undervalued
P/B 4.65Y avg ≈7.3 ≈7.3 1.3 Overvalued
Price / FCF -2.35Y avg ≈-5.8 ≈-5.8 · ·
Price / Cash Flow -2.45Y avg ≈-6.0 ≈-6.0 · ·
Price / Tangible Book 4.65Y avg ≈17.0 ≈17.0 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -162.2%
Next Report Nov 02, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 11, 2026 $-0.03 $0.01 -394.1%
March 31, 2026 $-0.04 $-0.02 -161.4%
Dec. 31, 2025 $-0.02 $-0.02 2.0%
Sept. 30, 2025 $-0.04 $-0.02 -161.4%
June 30, 2025 $-0.02 $-0.01 -96.1%
March 31, 2025 $0.01 $-0.01 —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 17
Metric Trend 2025202420232022202120202019201820172016
Revenue $155M$144M$127M$108M$86M$89M$146M$77M$31M$1M
Cost of Revenue $41M$39M$65M$55M$46M$36M$62M$28M$5M$35.0K
Gross Profit $114M$106M$62M$53M······
R&D Expense $12M$17M$39M$83M$131M$175M$167M$140M$139M$103M
SG&A Expense $55M$53M$66M$62M$40M$42M$38M$29M$26M$21M
Operating Expenses $116M$117M$173M$227M$304M$317M$357M$261M$225M$172M
Operating Income $-3M$-12M$-111M$-175M$-218M$-228M$-211M$-184M$-195M$-171M
Interest Expense ··$4M$2M$2M$2M$1M$3M$4M$3M
Interest Income $2M$4M$3M$2M$433.0K$4M$7M$6M$1M$445.0K
Other Non-op $1M$430.0K$560.0K$-7M$-878.0K$-847.0K$158.0K$2M$-38.0K$-9.0K
Income Tax $0$0$0$0$0$0$0$0$0$0
Net Income $-20M$-14M$-111M$-182M$-221M$-227M$-205M$-179M$-197M$-173M
EPS (Basic) $-0.12$-0.09$-0.80$-1.67$-2.24·····
EPS (Diluted) $-0.12$-0.09$-0.80$-1.67$-2.24·····
Shares (Basic) 166,707,000152,449,000138,135,000108,876,00098,471·····
Shares (Diluted) 166,707,000152,449,000138,135,000108,876,00098,471·····
EBITDA $-224.0K$-9M$-108M$-172M$-215M$-225M$-209M$-182M$-193M$-171M
Balance Sheet 23
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents $29M$26M$29M$15M$91M$105M$72M$32M$145M$13M
Short-term Investments ·······$301M$28M$38M
Receivables $90M$79M$60M$52M$35M$42M$40M$65M$42M$2M
Inventory $93M$53M$42M$55M$48M$42M$25M$39M$10M$5M
Prepaid Expense $9M$18M$6M$14M$13M$22M$23M$11M$4M$4M
Current Assets $238M$209M$189M$205M$254M$314M$479M$447M$228M$62M
PP&E (Net) $12M$15M$20M$22M$24M$23M$20M$15M$6M$5M
PP&E (Gross) $25M$33M$37M$36M$37M$34M$28M$23M$14M$12M
Accum. Depreciation $13M$18M$17M$14M$13M$11M$8M$8M$8M$7M
Other Non-current Assets $5M$6M$8M$16M$18M$346.0K$346.0K$254.0K$263.0K$263.0K
Total Assets $256M$233M$223M$251M$306M$354M$513M$462M$234M$67M
Accounts Payable $9M$12M$3M$3M$4M$525.0K$3M$17M$19M$7M
Current Liabilities $96M$91M$80M$82M$71M$103M$97M$92M$103M$39M
Capital Leases $0·$3M$5M$8M$15M$12M···
Other Non-current Liabilities $5M$615.0K$241.0K$241.0K······
Total Liabilities $242M$267M$256M$237M$228M$117M$109M$92M$103M$89M
Common Stock $2M$2M$2M$1M$1M$913.0K$903.0K$782.0K$646.0K$394.0K
Paid-in Capital $1.95B$1.88B$1.87B$1.81B$1.69B$1.63B$1.57B$1.33B$914M$564M
Retained Earnings $-1.94B$-1.92B$-1.91B$-1.80B$-1.61B$-1.39B$-1.17B$-961M$-783M$-586M
AOCI $4.0K$13.0K$13.0K$-19.0K$-6.0K$257.0K$85.0K$-87.0K$-10.0K$-17.0K
Stockholders' Equity $14M$-34M$-34M$14M$78M$236M$404M$370M$131M$-21M
Liabilities + Equity $256M$233M$223M$251M$306M$354M$513M$462M$234M$67M
Shares Outstanding 188,314,430152,127,878150,285,044119,154,538102,005,00091,310,00090,304,00078,174,00064,609,00039,355
Cash Flow 13
Metric Trend 2025202420232022202120202019201820172016
D&A $2M$2M$3M$3M$3M$3M$2M$2M$2M$1M
Stock-based Comp $10M$13M$33M$43M$47M$50M$51M$33M$31M$26M
Restructuring ·····$6M····
Other Non-cash $-20M$-24M$16M$-11M$-33M$-11M$27M$-48M$-5M·
Operating Cash Flow $-28M$-23M$-59M$-147M$-203M$-185M$-125M$-192M$-170M$-134M
CapEx $317.0K$2M$2M$2M$3M$7M$7M$9M$3M$3M
Investing Cash Flow $16M$19M$18M$-3M$33M$209M$-22M$-279M$8M$15M
Net Debt Issued ·······$-25M$-25M·
Stock Issued $18M·$30M$75M··$162M$363M$306M·
Net Stock Activity $18M·$30M$75M··$162M···
Financing Cash Flow $14M$940.0K$54M$75M$156M$9M$186M$358M$294M$57M
Net Change in Cash $3M$-3M$13M$-75M$-15M$33M$40M$-113M$131M$-62M
Free Cash Flow $-28M$-24M$-60M$-149M$-206M$-192M$-132M$-201M$-173M$-137M
Profitability 6
Metric Trend 2025202420232022202120202019201820172016
Gross Margin 73.3%73.2%48.8%·······
Operating Margin -1.6%-8.0%-87.1%-162.2%-252.3%-257.4%-144.3%-237.4%-632.4%-13363.2%
Net Margin -13.0%-9.4%-87.0%-169.0%-255.6%-256.4%-140.3%-230.8%-641.9%-13537.4%
EBITDA Margin -0.14%-6.3%-84.8%-159.5%-248.8%-254.2%-142.9%-235.5%-627.4%-13363.2%
ROA -8.3%-6.0%-46.7%-65.4%-67.0%-52.5%-42.0%-51.3%-130.9%-168.7%
ROE 312.5%36.9%358.0%-1010.6%-224.7%-88.5%-59.4%-46.0%-359.4%-357.5%
Liquidity & Solvency 3
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 2.52.32.42.53.63.15.04.92.21.6
Quick Ratio 1.21.11.10.81.81.41.24.32.11.4
Interest Coverage ··-28.6-70.6-90.4-120.0-143.1-68.8-49.4-64.2
Efficiency 3
Metric Trend 2025202420232022202120202019201820172016
Asset Turnover 0.60.60.50.40.30.20.30.20.20.0
Inventory Turnover 0.60.81.31.11.01.11.91.10.60.0
Receivables Turnover 1.82.12.32.52.22.22.81.51.41.3
Per Share 5
Metric Trend 2025202420232022202120202019201820172016
Book Value / Share $0.08$-0.22$-0.23$0.11$0.76$2.59$4.47$4.74$2029.69$-0.54
Revenue / Share $0.93$0.95$0.92$988.94······
Cash Flow / Share $-0.17$-0.15$-0.43$-1349.35······
Cash / Share $0.15$0.17$0.19$0.13$0.89$1.15$0.80$0.41$2237.82$0.34
EPS (TTM) $-0.12$-0.09$-0.80$-1.67$-2.24·····
Growth Rates 3
Metric Trend 2025202420232022202120202019201820172016
Revenue YoY 7.4%13.6%18.0%24.7%-2.6%·····
Revenue CAGR 3Y 12.9%18.7%12.8%·······
Revenue CAGR 5Y 11.8%·········
Valuation (TTM) 10
Metric Trend 2025202420232022202120202019201820172016
Revenue TTM $155M$144M$127M$108M$86M$89M$146M$77M$31M$1M
Net Income TTM $-20M$-14M$-111M$-182M$-221M$-227M$-205M$-179M$-197M$-173M
Market Cap $245M$233M$255M$298M$931M$1.93B$2.12B$2.03B$1M$516M
P/E -10.8-17.0-2.1-1.5-4.1·····
P/S 1.61.62.02.810.821.814.526.20.0403.1
P/B 17.1-6.9-7.521.912.08.25.35.50.0-24.3
P / Tangible Book 17.1··21.912.08.2····
P / Cash Flow -8.9-10.3-4.3-2.0-4.6-10.5-17.0-10.6-0.0-3.8
P / FCF -8.8-9.6-4.2-2.0-4.5-10.1-16.1-10.1-0.0-3.8
Earnings Yield -9.2%-5.9%-47.1%-66.8%-24.5%·····

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $155M $144M $127M $108M $86M
Gross Margin % 73.3% 73.2% 48.8% · ·
Operating Margin % -1.6% -8.0% -87.1% -162.2% -252.3%
Net Income $-20M $-14M $-111M $-182M $-221M
Diluted EPS $-0.12 $-0.09 $-0.80 $-1.67 $-2.24

Institutional owners (13F) 182 filers · $72.8M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 182
Value held $72.8M
New positions 22
Exited positions 21
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
22 (-15 vs prior Q) 21 (-6 vs prior Q) 58 (+7 vs prior Q) 42 (-2 vs prior Q) -23.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Rubric Capital Management LP $12,823,986 30,046,828 17.60% Shares
VANGUARD GROUP INC $12,766,499 9,820,384 17.53% Shares
Clearline Capital LP $4,858,675 11,383,961 6.67% Shares
BlackRock, Inc. $4,503,060 10,550,750 6.18% Shares
Velan Capital Investment Management LP $3,735,904 8,753,290 5.13% Shares
VANGUARD CAPITAL MANAGEMENT LLC $3,323,230 7,782,741 4.56% Shares
Tejara Capital Ltd $2,778,807 6,510,795 3.81% Shares
TANG CAPITAL MANAGEMENT LLC $2,667,500 6,250,000 3.66% Shares
GEODE CAPITAL MANAGEMENT, LLC $1,823,405 4,270,980 2.50% Shares
MILLENNIUM MANAGEMENT LLC $1,737,119 4,070,101 2.38% Shares
JW Asset Management, LLC $1,600,958 3,751,073 2.20% Shares
Stonepine Capital Management, LLC $1,500,000 1,000,000 2.06% Call option
STATE STREET CORP $1,377,948 3,228,557 1.89% Shares
UBS Group AG $1,279,750 2,997,073 1.76% Shares
Pale Fire Capital SE $1,071,899 2,511,478 1.47% Shares
MARSHALL WACE, LLP $1,012,302 2,354,193 1.39% Shares
Caption Management, LLC $896,280 2,100,000 1.23% Put option
Congress Park Capital LLC $860,620 2,016,447 1.18% Shares
Richmond Brothers, Inc. $764,961 1,792,319 1.05% Shares
TWO SIGMA ADVISERS, LP $675,442 519,571 0.93% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $674,878 1,580,510 0.93% Shares
AQR CAPITAL MANAGEMENT LLC $663,186 1,553,857 0.91% Shares
RENAISSANCE TECHNOLOGIES LLC $643,145 1,506,900 0.88% Shares
VANGUARD FIDUCIARY TRUST CO $582,906 1,365,119 0.80% Shares
GOLDMAN SACHS GROUP INC $567,539 1,329,754 0.78% Shares
PANAGORA ASSET MANAGEMENT INC $547,071 1,281,796 0.75% Shares
NORTHERN TRUST CORP $522,181 1,223,480 0.72% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $519,613 1,217,463 0.71% Shares
Qube Research & Technologies Ltd $435,802 1,021,092 0.60% Shares
Caption Management, LLC $426,800 1,000,000 0.59% Shares
CM Management, LLC $426,800 1,000,000 0.59% Shares
NEW YORK STATE COMMON RETIREMENT FUND $296,270 694,165 0.41% Shares
ALLIANCEBERNSTEIN L.P. $239,958 299,910 0.33% Shares
Stonepine Capital Management, LLC $209,468 490,787 0.29% Shares
NEXPOINT ASSET MANAGEMENT, L.P. $203,050 475,750 0.28% Shares
DIADEMA PARTNERS LP $195,783 458,723 0.27% Shares
Invesco Ltd. $173,565 406,668 0.24% Shares
Xcelsior Advisor Partners LLC $173,186 405,777 0.24% Shares
Bank of New York Mellon Corp $168,944 395,838 0.23% Shares
Apeiron RIA LLC $158,163 370,579 0.22% Shares
Squarepoint Ops LLC $137,078 321,177 0.19% Shares
Glenmede Investment Management, LP $132,710 105,326 0.18% Shares
TWO SIGMA INVESTMENTS, LP $113,663 266,314 0.16% Shares
FMR LLC $96,800 226,803 0.13% Shares
Nuveen, LLC $94,659 221,787 0.13% Shares
Abel Hall, LLC $90,987 213,185 0.12% Shares
CAROLINAS WEALTH CONSULTING LLC $90,983 41,356 0.12% Shares
Horan Securities, Inc. $86,091 41,590 0.12% Shares
RHUMBLINE ADVISERS $83,482 195,537 0.11% Shares
Cutter & CO Brokerage, Inc. $80,223 36,465 0.11% Shares

Show all 182 institutional owners →

Activists & 5%+ owners 3 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Rubric Capital Management LP, David Rosen ×6 filings Oct. 17, 2025 15.90% Amendment · SEC
Tang Capital Partners, LP, Tang Capital Management, LLC, Kevin Tang ×20 filings Jan. 7, 2020 · Initial filing · SEC
Felix J. Baker, Julian C. Baker ×3 filings July 7, 2011 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 40 insiders · 21 officers · 21 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Craig A Collard Chief Executive Officer July 31, 2026 M 856,492 0 0 $0
Barry D Quart Chief Executive Officer Jan. 18, 2023 A 177,989 0 0 $0
Ronald J Prentki President & CEO Feb. 17, 2010 A 40,539 0 0 $0
Michael Oconnell Chief Executive Officer Jan. 10, 2006 A 132,200 0 0 $0
Ira Duarte EVP, Chief Financial Officer July 31, 2026 M 281,899 0 0 $0
Robert Hoffman CFO & SVP, Finance Dec. 19, 2019 A 1,280 0 0 $0
Brian G. Drazba VP, Finance & CFO Oct. 31, 2016 J 3,798 0 0 $0
John Whelan CFO July 18, 2013 M 254,088 0 0 $0
Stephen Whiteford V.P., Finance & CFO Dec. 15, 2006 A 15,000 0 0 $0
John Poyhonen President & CCO April 13, 2023 M 46,648 0 0 $0
Robert Rosen President Dec. 15, 2018 A 2,640 0 0 $0
David Leslie Szekeres EVP, Chief Operating Officer July 13, 2023 M 33,754 0 0 $0
Michael A Adam Chief Operating Officer Feb. 8, 2013 A · 0 0 $0
William P Forbes EVP, Chief Development Officer July 31, 2026 M 241,173 0 0 $0
Lisa Peraza VP, Chief Accounting Officer Jan. 19, 2024 A 55,907 0 0 $0
Kimberly Manhard EVP, Drug Development April 13, 2023 M 28,330 0 0 $0
Marshall Paul SVP, Technical Operations March 21, 2016 M 2,200 0 0 $0
Neil James Clendeninn SVP & Chief Medical Officer Oct. 12, 2015 A · 0 0 $0
Mark S. Gelder MD SVP & Chief Medical Officer Dec. 12, 2014 A · 0 0 $0
John Barr Vice President of R&D July 8, 2011 A 51,772 0 0 $0
Anastassios D. Retzios VP of Clinical Development Jan. 15, 2008 A · 0 0 $0
Thomas Cusack Director Jan. 30, 2026 A 53,960 0 0 $0
Morgan Adam Director Jan. 30, 2026 A 123,737 0 0 $0
Sharmila Dissanaike Director Jan. 30, 2026 A 53,960 0 0 $0
Michael Kaseta Director Jan. 30, 2026 A 53,960 0 0 $0
Waage Christian Director Jan. 30, 2026 A 53,960 0 0 $0
Craig A Johnson Director Jan. 30, 2026 A 53,960 0 0 $0
Susan Rodriguez Director Jan. 31, 2025 A 87,180 0 0 $0
Stephen Davis Director Dec. 16, 2022 A 52,032 0 0 $0
KEVIN TANG Director Dec. 19, 2019 A 5,799,810 0 0 $0
Greg Turnbull Director May 29, 2012 A 245,092 0 0 $0
Paul Goddard Director May 29, 2012 A 214,683 0 0 $0
Toby Rosenblatt Director May 20, 2010 A 210,234 0 0 $0
Robert L Zerbe MD Director May 20, 2010 A 202,072 0 0 $0
Peter Riepenhausen Director May 28, 2008 A 9,000 0 0 $0
Arthur T Taylor Director May 28, 2008 A 12,000 0 0 $0
Dennis L Winger Director Aug. 11, 2006 A 69,544 0 0 $0
Stephen A Drury Director Aug. 11, 2006 J 83,283 0 0 $0
SPCH, LLLP 10% owner Jan. 1, 2013 J 0 0 0 $0
Mark Earl Hensley · Aug. 6, 2026 M 170,901 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 15 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.59% 376,931 SH Oct. 2, 2026 Daily
IWC · iShares Trust 0.01% 533,800 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.00% 1,361,330 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.00% 195,097 SH Oct. 2, 2026 Daily
RSSL · Global X Funds 0.00% 76,332 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.00% 3,617,230 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 2,063,361 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 5,474,947 SH Aug. 19, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.00% 925,988 SH Aug. 19, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 13,208 SH Aug. 19, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 156,616 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 12,513 SH Aug. 19, 2026 Daily
IWV · iShares Trust 0.00% 28,936 SH Sept. 3, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 472,185 SH Aug. 19, 2026 Daily
IWN · iShares Trust · 507,316 SH Sept. 11, 2026 Daily

HRTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 7 analysts SELL
Median target $7.00 +1913.8%
0 0.0% Strong Buy
0 0.0% Buy
4 57.1% Hold
1 14.3% Sell
2 28.6% Strong Sell

12-Month Price Target

3 analysts · 2026-10-01

Mean target $7.00 +1913.8%

← Below all targets Current price $0.35
Low$5.00 Mean$7.00 High$9.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
HRTX $245M -10.8 7.4% -13.0% 312.5% 73.3%
GANX $135M -5.3 -60.6% · -181.1% ·
TENX $114M -9.1 · · -52.5% ·
ALDX $312M -9.2 · · -68.0% ·
RNXT · -2.6 2511.6% · · ·
SPRO $131M 15.5 39.2% 12.8% 18.7% ·
GRML · · · · -104.9% ·
RNTX · -0.6 · · · ·
XBIT · -1.6 · · · ·

Latest News Recent headlines mentioning this company

23

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26

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Source: SEC 10-Q filed Aug 10, 2026