HRTX Heron Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.31
Price · Aug 19, 2026
Fundamentals as of Aug 10, 2026

HRTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.31
Market Cap
$58M
P/E (TTM)
-2.6
EPS (TTM)
$-0.12
Revenue (TTM)
$155M
Div Yield
ROE
312.5%
Debt/Equity
52W Range
$0 – $2

HRTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $155M
10-point trend, +12011.3%
2016-12-31 2025-12-31
EPS $-0.12
5-point trend, +94.6%
2021-12-31 2025-12-31
Free Cash Flow $-28M
10-point trend, +79.7%
2016-12-31 2025-12-31
Margins -13.0%
3-point trend, +50.4%
2023-12-31 2025-12-31

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
HRTX
Peer Median
P/E (TTM)
5-point trend, -165.8%
-2.6
P/S (TTM)
5-point trend, -85.3%
0.4
165.8
P/B
5-point trend, +42.3%
4.0
1.6
Price / FCF
5-point trend, -94.4%
-2.1

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
HRTX
Peer Median
Gross Margin
3-point trend, +50.4%
73.3%
71.1%
Operating Margin
5-point trend, +99.3%
-1.6%
Net Profit Margin
5-point trend, +94.9%
-13.0%
-2229.6%
ROA
5-point trend, +87.7%
-8.3%
-64.3%
ROE
5-point trend, +239.1%
312.5%
-102.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
HRTX
Peer Median
Current Ratio
5-point trend, -30.8%
2.5
4.8
Quick Ratio
5-point trend, -30.6%
1.2

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
HRTX
Peer Median
Revenue YoY
5-point trend, +79.4%
7.4%
Revenue CAGR 3Y
5-point trend, +79.4%
12.9%
Revenue CAGR 5Y
5-point trend, +79.4%
11.8%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
HRTX
Peer Median
EPS (Diluted)
5-point trend, +94.6%
$-0.12

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
HRTX
Peer Median

HRTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 8 analysts
  • Strong Buy 2 25.0%
  • Buy 4 50.0%
  • Hold 2 25.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

1 analysts · 2026-08-13
Median target $2.00 +553.2%
Mean target $2.00 +553.2%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.01%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.03 $0.01 -0.04%
March 31, 2026 $-0.04 $-0.02 -0.02%
Dec. 31, 2025 $-0.02 $-0.02 0.00%
Sept. 30, 2025 $-0.04 $-0.02 -0.02%
June 30, 2025 $-0.02 $-0.01 -0.01%
March 31, 2025 $0.01 $-0.01 0.02%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
HRTX $245M -10.8 7.4% -13.0% 312.5% 73.3%
TENX $114M -9.1 -52.5%
PMVP $67M -0.8 -40.5% -1226.8% -63.4%
MNOV $64M -5.5 -2928.8% -27.1%
BOLD $27M -0.5 -46.7%
INMB $41M -0.8 257.1% -91866.0% -175.3%
EXOZ $92M -10.0 -172.3%
INKT -3.8 4.5% -6931.8% 63.4%
CLNN $64M -41.5% -13086.5% 200.2%
RNXT -2.6 2511.6%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Revenue 10-point trend, +12011.3% $155M $144M $127M $108M $86M $89M $146M $77M $31M $1M
Cost of Revenue 10-point trend, +118034.3% $41M $39M $65M $55M $46M $36M $62M $28M $5M $35.0K
Gross Profit 4-point trend, +115.1% $114M $106M $62M $53M · · · · · ·
R&D Expense 10-point trend, -87.9% $12M $17M $39M $83M $131M $175M $167M $140M $139M $103M
SG&A Expense 10-point trend, +155.6% $55M $53M $66M $62M $40M $42M $38M $29M $26M $21M
Operating Expenses 10-point trend, -32.6% $116M $117M $173M $227M $304M $317M $357M $261M $225M $172M
Operating Income 10-point trend, +98.5% $-3M $-12M $-111M $-175M $-218M $-228M $-211M $-184M $-195M $-171M
Interest Expense 8-point trend, +45.2% · · $4M $2M $2M $2M $1M $3M $4M $3M
Interest Income 10-point trend, +337.8% $2M $4M $3M $2M $433.0K $4M $7M $6M $1M $445.0K
Other Non-op 10-point trend, +14977.8% $1M $430.0K $560.0K $-7M $-878.0K $-847.0K $158.0K $2M $-38.0K $-9.0K
Income Tax Flat — no change across 10 periods $0 $0 $0 $0 $0 $0 $0 $0 $0 $0
Net Income 10-point trend, +88.3% $-20M $-14M $-111M $-182M $-221M $-227M $-205M $-179M $-197M $-173M
EPS (Basic) 5-point trend, +94.6% $-0.12 $-0.09 $-0.80 $-1.67 $-2.24 · · · · ·
EPS (Diluted) 5-point trend, +94.6% $-0.12 $-0.09 $-0.80 $-1.67 $-2.24 · · · · ·
Shares (Basic) 5-point trend, +169195.5% 166,707,000 152,449,000 138,135,000 108,876,000 98,471 · · · · ·
Shares (Diluted) 5-point trend, +169195.5% 166,707,000 152,449,000 138,135,000 108,876,000 98,471 · · · · ·
EBITDA 10-point trend, +99.9% $-224.0K $-9M $-108M $-172M $-215M $-225M $-209M $-182M $-193M $-171M
Balance Sheet 23
Annual Balance Sheet data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents 10-point trend, +113.6% $29M $26M $29M $15M $91M $105M $72M $32M $145M $13M
Short-term Investments 3-point trend, +696.7% · · · · · · · $301M $28M $38M
Receivables 10-point trend, +4470.8% $90M $79M $60M $52M $35M $42M $40M $65M $42M $2M
Inventory 10-point trend, +1636.8% $93M $53M $42M $55M $48M $42M $25M $39M $10M $5M
Prepaid Expense 10-point trend, +145.7% $9M $18M $6M $14M $13M $22M $23M $11M $4M $4M
Current Assets 10-point trend, +283.1% $238M $209M $189M $205M $254M $314M $479M $447M $228M $62M
PP&E (Net) 10-point trend, +144.3% $12M $15M $20M $22M $24M $23M $20M $15M $6M $5M
PP&E (Gross) 10-point trend, +116.3% $25M $33M $37M $36M $37M $34M $28M $23M $14M $12M
Accum. Depreciation 10-point trend, +94.7% $13M $18M $17M $14M $13M $11M $8M $8M $8M $7M
Other Non-current Assets 10-point trend, +1956.3% $5M $6M $8M $16M $18M $346.0K $346.0K $254.0K $263.0K $263.0K
Total Assets 10-point trend, +279.2% $256M $233M $223M $251M $306M $354M $513M $462M $234M $67M
Accounts Payable 10-point trend, +32.0% $9M $12M $3M $3M $4M $525.0K $3M $17M $19M $7M
Current Liabilities 10-point trend, +148.1% $96M $91M $80M $82M $71M $103M $97M $92M $103M $39M
Capital Leases 6-point trend, -100.0% $0 · $3M $5M $8M $15M $12M · · ·
Other Non-current Liabilities 4-point trend, +1895.0% $5M $615.0K $241.0K $241.0K · · · · · ·
Total Liabilities 10-point trend, +172.2% $242M $267M $256M $237M $228M $117M $109M $92M $103M $89M
Common Stock 10-point trend, +377.9% $2M $2M $2M $1M $1M $913.0K $903.0K $782.0K $646.0K $394.0K
Paid-in Capital 10-point trend, +245.7% $1.95B $1.88B $1.87B $1.81B $1.69B $1.63B $1.57B $1.33B $914M $564M
Retained Earnings 10-point trend, -231.0% $-1.94B $-1.92B $-1.91B $-1.80B $-1.61B $-1.39B $-1.17B $-961M $-783M $-586M
AOCI 10-point trend, +123.5% $4.0K $13.0K $13.0K $-19.0K $-6.0K $257.0K $85.0K $-87.0K $-10.0K $-17.0K
Stockholders' Equity 10-point trend, +167.4% $14M $-34M $-34M $14M $78M $236M $404M $370M $131M $-21M
Liabilities + Equity 10-point trend, +279.2% $256M $233M $223M $251M $306M $354M $513M $462M $234M $67M
Shares Outstanding 10-point trend, +478401.9% 188,314,430 152,127,878 150,285,044 119,154,538 102,005,000 91,310,000 90,304,000 78,174,000 64,609,000 39,355
Cash Flow 13
Annual Cash Flow data for HRTX
Metric Trend 2025202420232022202120202019201820172016
D&A 10-point trend, +110.6% $2M $2M $3M $3M $3M $3M $2M $2M $2M $1M
Stock-based Comp 10-point trend, -60.2% $10M $13M $33M $43M $47M $50M $51M $33M $31M $26M
Restructuring · · · · · $6M · · · ·
Other Non-cash 9-point trend, -310.4% $-20M $-24M $16M $-11M $-33M $-11M $27M $-48M $-5M ·
Operating Cash Flow 10-point trend, +79.4% $-28M $-23M $-59M $-147M $-203M $-185M $-125M $-192M $-170M $-134M
CapEx 10-point trend, -89.9% $317.0K $2M $2M $2M $3M $7M $7M $9M $3M $3M
Investing Cash Flow 10-point trend, +7.6% $16M $19M $18M $-3M $33M $209M $-22M $-279M $8M $15M
Net Debt Issued Flat — no change across 2 periods · · · · · · · $-25M $-25M ·
Stock Issued 6-point trend, -94.0% $18M · $30M $75M · · $162M $363M $306M ·
Net Stock Activity 4-point trend, -88.7% $18M · $30M $75M · · $162M · · ·
Financing Cash Flow 10-point trend, -74.9% $14M $940.0K $54M $75M $156M $9M $186M $358M $294M $57M
Net Change in Cash 10-point trend, +104.6% $3M $-3M $13M $-75M $-15M $33M $40M $-113M $131M $-62M
Free Cash Flow 10-point trend, +79.7% $-28M $-24M $-60M $-149M $-206M $-192M $-132M $-201M $-173M $-137M
Profitability 6
Annual Profitability data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Gross Margin 3-point trend, +50.4% 73.3% 73.2% 48.8% · · · · · · ·
Operating Margin 10-point trend, +100.0% -1.6% -8.0% -87.1% -162.2% -252.3% -257.4% -144.3% -237.4% -632.4% -13363.2%
Net Margin 10-point trend, +99.9% -13.0% -9.4% -87.0% -169.0% -255.6% -256.4% -140.3% -230.8% -641.9% -13537.4%
EBITDA Margin 10-point trend, +100.0% -0.14% -6.3% -84.8% -159.5% -248.8% -254.2% -142.9% -235.5% -627.4% -13363.2%
ROA 10-point trend, +95.1% -8.3% -6.0% -46.7% -65.4% -67.0% -52.5% -42.0% -51.3% -130.9% -168.7%
ROE 10-point trend, +187.4% 312.5% 36.9% 358.0% -1010.6% -224.7% -88.5% -59.4% -46.0% -359.4% -357.5%
Liquidity & Solvency 3
Annual Liquidity & Solvency data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 10-point trend, +54.4% 2.5 2.3 2.4 2.5 3.6 3.1 5.0 4.9 2.2 1.6
Quick Ratio 10-point trend, -10.3% 1.2 1.1 1.1 0.8 1.8 1.4 1.2 4.3 2.1 1.4
Interest Coverage 8-point trend, +55.4% · · -28.6 -70.6 -90.4 -120.0 -143.1 -68.8 -49.4 -64.2
Efficiency 3
Annual Efficiency data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Asset Turnover 10-point trend, +4968.0% 0.6 0.6 0.5 0.4 0.3 0.2 0.3 0.2 0.2 0.0
Inventory Turnover 10-point trend, +4226.7% 0.6 0.8 1.3 1.1 1.0 1.1 1.9 1.1 0.6 0.0
Receivables Turnover 10-point trend, +40.9% 1.8 2.1 2.3 2.5 2.2 2.2 2.8 1.5 1.4 1.3
Per Share 5
Annual Per Share data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Book Value / Share 10-point trend, +114.1% $0.08 $-0.22 $-0.23 $0.11 $0.76 $2.59 $4.47 $4.74 $2029.69 $-0.54
Revenue / Share 4-point trend, -99.9% $0.93 $0.95 $0.92 $988.94 · · · · · ·
Cash Flow / Share 4-point trend, +100.0% $-0.17 $-0.15 $-0.43 $-1349.35 · · · · · ·
Cash / Share 10-point trend, -55.4% $0.15 $0.17 $0.19 $0.13 $0.89 $1.15 $0.80 $0.41 $2237.82 $0.34
EPS (TTM) 5-point trend, +94.6% $-0.12 $-0.09 $-0.80 $-1.67 $-2.24 · · · · ·
Growth Rates 3
Annual Growth Rates data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Revenue YoY 5-point trend, +384.2% 7.4% 13.6% 18.0% 24.7% -2.6% · · · · ·
Revenue CAGR 3Y 3-point trend, +1.1% 12.9% 18.7% 12.8% · · · · · · ·
Revenue CAGR 5Y 11.8% · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for HRTX
Metric Trend 2025202420232022202120202019201820172016
Revenue TTM 10-point trend, +12011.3% $155M $144M $127M $108M $86M $89M $146M $77M $31M $1M
Net Income TTM 10-point trend, +88.3% $-20M $-14M $-111M $-182M $-221M $-227M $-205M $-179M $-197M $-173M
Market Cap 10-point trend, -52.5% $245M $233M $255M $298M $931M $1.93B $2.12B $2.03B $1M $516M
P/E 5-point trend, -165.8% -10.8 -17.0 -2.1 -1.5 -4.1 · · · · ·
P/S 10-point trend, -99.6% 1.6 1.6 2.0 2.8 10.8 21.8 14.5 26.2 0.0 403.1
P/B 10-point trend, +170.4% 17.1 -6.9 -7.5 21.9 12.0 8.2 5.3 5.5 0.0 -24.3
P / Tangible Book 4-point trend, +109.0% 17.1 · · 21.9 12.0 8.2 · · · ·
P / Cash Flow 10-point trend, -130.8% -8.9 -10.3 -4.3 -2.0 -4.6 -10.5 -17.0 -10.6 -0.0 -3.8
P / FCF 10-point trend, -133.5% -8.8 -9.6 -4.2 -2.0 -4.5 -10.1 -16.1 -10.1 -0.0 -3.8
Earnings Yield 5-point trend, +62.4% -9.2% -5.9% -47.1% -66.8% -24.5% · · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $155M$144M$127M$108M$86M
Gross Margin % 73.3%73.2%48.8%
Operating Margin % -1.6%-8.0%-87.1%-162.2%-252.3%
Net Income $-20M$-14M$-111M$-182M$-221M
Diluted EPS $-0.12$-0.09$-0.80$-1.67$-2.24
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 2.52.32.42.53.6
Quick Ratio 1.21.11.10.81.8
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-28M$-24M$-60M$-149M$-206M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 184 filers · $51.8M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
25 (-7 vs prior Q) 21 (-6 vs prior Q) 50 (+3 vs prior Q) 40 (-6 vs prior Q) -15.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Rubric Capital Management LP $12,823,986 30,046,828 24.76% Shares
Clearline Capital LP $4,858,675 11,383,961 9.38% Shares
Velan Capital Investment Management LP $3,735,904 8,753,290 7.21% Shares
VANGUARD CAPITAL MANAGEMENT LLC $3,323,230 7,782,741 6.42% Shares
Tejara Capital Ltd $2,778,807 6,510,795 5.36% Shares
TANG CAPITAL MANAGEMENT LLC $2,667,500 6,250,000 5.15% Shares
MILLENNIUM MANAGEMENT LLC $1,737,119 4,070,101 3.35% Shares
JW Asset Management, LLC $1,600,958 3,751,073 3.09% Shares
GEODE CAPITAL MANAGEMENT, LLC $1,543,336 3,614,773 2.98% Shares
VANGUARD GROUP INC $1,500,729 1,154,407 2.90% Shares
Stonepine Capital Management, LLC $1,500,000 1,000,000 2.90% Call option
STATE STREET CORP $1,377,948 3,228,557 2.66% Shares
Pale Fire Capital SE $1,071,899 2,511,478 2.07% Shares
Caption Management, LLC $896,280 2,100,000 1.73% Put option
Congress Park Capital LLC $860,620 2,016,447 1.66% Shares
TWO SIGMA ADVISERS, LP $675,442 519,571 1.30% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $674,878 1,580,510 1.30% Shares
RENAISSANCE TECHNOLOGIES LLC $643,145 1,506,900 1.24% Shares
VANGUARD FIDUCIARY TRUST CO $582,906 1,365,119 1.13% Shares
PANAGORA ASSET MANAGEMENT INC $547,071 1,281,796 1.06% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $519,613 1,217,463 1.00% Shares
Qube Research & Technologies Ltd $435,802 1,021,092 0.84% Shares
Caption Management, LLC $426,800 1,000,000 0.82% Shares
CM Management, LLC $426,800 1,000,000 0.82% Shares
NEW YORK STATE COMMON RETIREMENT FUND $296,270 694,165 0.57% Shares
ALLIANCEBERNSTEIN L.P. $239,958 299,910 0.46% Shares
Stonepine Capital Management, LLC $209,468 490,787 0.40% Shares
DIADEMA PARTNERS LP $195,783 458,723 0.38% Shares
Xcelsior Advisor Partners LLC $173,186 405,777 0.33% Shares
Apeiron RIA LLC $158,163 370,579 0.31% Shares
Squarepoint Ops LLC $137,078 321,177 0.26% Shares
Integrated Wealth Concepts LLC $136,107 318,903 0.26% Shares
Glenmede Investment Management, LP $132,710 105,326 0.26% Shares
Richmond Brothers, Inc. $131,755 308,706 0.25% Shares
TWO SIGMA INVESTMENTS, LP $113,663 266,314 0.22% Shares
MARSHALL WACE, LLP $105,194 244,638 0.20% Shares
NEXPOINT ASSET MANAGEMENT, L.P. $99,359 232,800 0.19% Shares
FMR LLC $96,800 226,803 0.19% Shares
Abel Hall, LLC $90,987 213,185 0.18% Shares
CAROLINAS WEALTH CONSULTING LLC $90,983 41,356 0.18% Shares
Horan Securities, Inc. $86,091 41,590 0.17% Shares
RHUMBLINE ADVISERS $83,482 195,537 0.16% Shares
Cutter & CO Brokerage, Inc. $80,223 36,465 0.15% Shares
Quinn Opportunity Partners LLC $74,837 175,344 0.14% Shares
GOLDMAN SACHS GROUP INC $74,770 175,188 0.14% Shares
DLK Investment Management, LLC $62,615 17,890 0.12% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $58,500 137,067 0.11% Shares
Bank of New York Mellon Corp $54,073 126,693 0.10% Shares
D. E. Shaw & Co., Inc. $51,402 120,435 0.10% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $51,341 120,293 0.10% Shares
Persistent Asset Partners Ltd $49,974 117,090 0.10% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $48,289 112,300 0.09% Call option
BANK OF AMERICA CORP /DE/ $46,165 108,369 0.09% Shares
Redwood Family Wealth LLC $45,015 105,472 0.09% Shares
Biltmore Family Office, LLC $42,680 100,000 0.08% Shares
DEUTSCHE BANK AG\ $41,409 96,300 0.08% Shares
IEQ CAPITAL, LLC $41,234 96,612 0.08% Shares
BARCLAYS PLC $37,172 87,094 0.07% Shares
SEARLE & CO. $36,812 86,250 0.07% Shares
Vanguard Global Advisers, LLC $35,764 83,756 0.07% Shares
BlackRock, Inc. $35,761 83,788 0.07% Shares
Russell Investments Group, Ltd. $34,675 81,246 0.07% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $31,406 73,585 0.06% Shares
MERCER GLOBAL ADVISORS INC /ADV $29,147 68,291 0.06% Shares
CITIGROUP INC $28,050 65,721 0.05% Shares
Invesco Ltd. $27,051 63,382 0.05% Shares
LPL Financial LLC $26,083 61,112 0.05% Shares
COMMONWEALTH EQUITY SERVICES, LLC $25,254 59,176 0.05% Shares
Anfield Capital Management, LLC $24,003 30,000 0.05% Shares
Mariner, LLC $23,896 55,972 0.05% Shares
NICOLET ADVISORY SERVICES, LLC $23,840 16,000 0.05% Shares
Chicago Partners Investment Group LLC $23,526 51,254 0.05% Shares
CWM, LLC $23,115 28,890 0.04% Shares
Cerity Partners LLC $22,473 52,654 0.04% Shares
CAPTRUST FINANCIAL ADVISORS $22,000 51,547 0.04% Shares
RAYMOND JAMES FINANCIAL INC $20,003 46,868 0.04% Shares
R Squared Ltd $19,935 46,708 0.04% Shares
Centiva Capital, LP $19,422 45,507 0.04% Shares
Nuveen Asset Management, LLC $19,408 12,685 0.04% Shares
INTECH INVESTMENT MANAGEMENT LLC $17,990 42,150 0.03% Shares
HORAN Wealth, LLC $17,751 41,590 0.03% Shares
Prospera Financial Services Inc $17,308 40,565 0.03% Shares
Cornerstone Select Advisors, LLC $17,057 39,964 0.03% Shares
NEUBERGER BERMAN GROUP LLC $16,647 38,987 0.03% Shares
Police & Firemen's Retirement System of New Jersey $16,369 38,352 0.03% Shares
GROUP ONE TRADING LLC $16,196 37,947 0.03% Shares
Creative Planning $15,306 35,862 0.03% Shares
Tower Research Capital LLC (TRC) $15,180 35,567 0.03% Shares
HSBC HOLDINGS PLC $14,464 33,381 0.03% Shares
DDFG, Inc $14,043 32,903 0.03% Shares
Concurrent Investment Advisors, LLC $13,625 31,923 0.03% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $13,425 32,397 0.03% Shares
CIBC WORLD MARKETS CORP $13,215 10,165 0.03% Shares
Skopos Labs, Inc. $12,744 15,927 0.02% Shares
CoreCap Advisors, LLC $12,125 28,409 0.02% Shares
Vanguard Personalized Indexing Management, LLC $11,641 27,276 0.02% Shares
DIVERSIFIED TRUST CO $11,306 26,492 0.02% Shares
CITADEL ADVISORS LLC $11,139 26,100 0.02% Call option
Pallas Capital Advisors LLC $10,968 25,699 0.02% Shares
JANE STREET GROUP, LLC $10,957 25,672 0.02% Shares

Company insiders 39 insiders · 21 officers · 21 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Craig A Collard Chief Executive Officer July 31, 2026 M 856,492 0 0 $0
Barry D Quart Chief Executive Officer Jan. 18, 2023 A 177,989 0 0 $0
Ronald J Prentki President & CEO Feb. 17, 2010 A 40,539 0 0 $0
Michael Oconnell Chief Executive Officer Jan. 10, 2006 A 132,200 0 0 $0
Ira Duarte EVP, Chief Financial Officer July 31, 2026 M 281,899 0 0 $0
Robert Hoffman CFO & SVP, Finance Dec. 19, 2019 A 1,280 0 0 $0
Brian G. Drazba VP, Finance & CFO Oct. 31, 2016 J 3,798 0 0 $0
John Whelan CFO July 18, 2013 M 254,088 0 0 $0
Stephen Whiteford V.P., Finance & CFO Dec. 15, 2006 A 15,000 0 0 $0
John Poyhonen President & CCO April 13, 2023 M 46,648 0 0 $0
Robert Rosen President Dec. 15, 2018 A 2,640 0 0 $0
David Leslie Szekeres EVP, Chief Operating Officer July 13, 2023 M 33,754 0 0 $0
Michael A Adam Chief Operating Officer Feb. 8, 2013 A 0 0 $0
William P Forbes EVP, Chief Development Officer July 31, 2026 M 241,173 0 0 $0
Lisa Peraza VP, Chief Accounting Officer Jan. 19, 2024 A 55,907 0 0 $0
Kimberly Manhard EVP, Drug Development April 13, 2023 M 28,330 0 0 $0
Marshall Paul SVP, Technical Operations March 21, 2016 M 2,200 0 0 $0
Neil James Clendeninn SVP & Chief Medical Officer Oct. 12, 2015 A 0 0 $0
Mark S. Gelder MD SVP & Chief Medical Officer Dec. 12, 2014 A 0 0 $0
John Barr Vice President of R&D July 8, 2011 A 51,772 0 0 $0
Anastassios D. Retzios VP of Clinical Development Jan. 15, 2008 A 0 0 $0
Thomas Cusack Director Jan. 30, 2026 A 53,960 0 0 $0
Morgan Adam Director Jan. 30, 2026 A 123,737 0 0 $0
Sharmila Dissanaike Director Jan. 30, 2026 A 53,960 0 0 $0
Michael Kaseta Director Jan. 30, 2026 A 53,960 0 0 $0
Waage Christian Director Jan. 30, 2026 A 53,960 0 0 $0
Craig A Johnson Director Jan. 30, 2026 A 53,960 0 0 $0
Susan Rodriguez Director Jan. 31, 2025 A 87,180 0 0 $0
Stephen Davis Director Dec. 16, 2022 A 52,032 0 0 $0
KEVIN TANG Director Dec. 19, 2019 A 5,799,810 0 0 $0
Greg Turnbull Director May 29, 2012 A 245,092 0 0 $0
Paul Goddard Director May 29, 2012 A 214,683 0 0 $0
Toby Rosenblatt Director May 20, 2010 A 210,234 0 0 $0
Robert L Zerbe MD Director May 20, 2010 A 202,072 0 0 $0
Peter Riepenhausen Director May 28, 2008 A 9,000 0 0 $0
Arthur T Taylor Director May 28, 2008 A 12,000 0 0 $0
Dennis L Winger Director Aug. 11, 2006 A 69,544 0 0 $0
Stephen A Drury Director Aug. 11, 2006 J 83,283 0 0 $0
Mark Earl Hensley Aug. 6, 2026 M 170,901 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Rubric Capital Management LP, David Rosen ×6 filings Oct. 17, 2025 15.90% Amendment SEC
Tang Capital Partners, LP, Tang Capital Management, LLC, Kevin Tang ×20 filings Jan. 7, 2020 Initial filing SEC
Felix J. Baker, Julian C. Baker ×3 filings July 7, 2011 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 22 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.28% 128,515 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.02% 537,335 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 67,617 NS April 30, 2026 N-PORT
IWO · iShares Trust 0.00% 1,328,289 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.00% 7,231 NS May 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.00% 198,683 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.00% 869,904 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.00% 3,609,893 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.00% 5,655 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.00% 505,371 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.00% 5,714 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 144 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 4,190 NS May 31, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 83,361 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 28,626 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 2,063,361 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 5,474,947 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.00% 925,988 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 13,208 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 156,616 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 12,513 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 472,185 SH Aug. 8, 2026 Daily