HRTX — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Rubric Capital Management LP | $12,823,986 | 30,046,828 | 17.60% | Shares |
| VANGUARD GROUP INC | $12,766,499 | 9,820,384 | 17.53% | Shares |
| Clearline Capital LP | $4,858,675 | 11,383,961 | 6.67% | Shares |
| BlackRock, Inc. | $4,503,060 | 10,550,750 | 6.18% | Shares |
| Velan Capital Investment Management LP | $3,735,904 | 8,753,290 | 5.13% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $3,323,230 | 7,782,741 | 4.56% | Shares |
| Tejara Capital Ltd | $2,778,807 | 6,510,795 | 3.81% | Shares |
| TANG CAPITAL MANAGEMENT LLC | $2,667,500 | 6,250,000 | 3.66% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $1,823,405 | 4,270,980 | 2.50% | Shares |
| MILLENNIUM MANAGEMENT LLC | $1,737,119 | 4,070,101 | 2.38% | Shares |
| JW Asset Management, LLC | $1,600,958 | 3,751,073 | 2.20% | Shares |
| Stonepine Capital Management, LLC | $1,500,000 | 1,000,000 | 2.06% | Call option |
| STATE STREET CORP | $1,377,948 | 3,228,557 | 1.89% | Shares |
| UBS Group AG | $1,279,750 | 2,997,073 | 1.76% | Shares |
| Pale Fire Capital SE | $1,071,899 | 2,511,478 | 1.47% | Shares |
| MARSHALL WACE, LLP | $1,012,302 | 2,354,193 | 1.39% | Shares |
| Caption Management, LLC | $896,280 | 2,100,000 | 1.23% | Put option |
| Congress Park Capital LLC | $860,620 | 2,016,447 | 1.18% | Shares |
| Richmond Brothers, Inc. | $764,961 | 1,792,319 | 1.05% | Shares |
| TWO SIGMA ADVISERS, LP | $675,442 | 519,571 | 0.93% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $674,878 | 1,580,510 | 0.93% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $663,186 | 1,553,857 | 0.91% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $643,145 | 1,506,900 | 0.88% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $582,906 | 1,365,119 | 0.80% | Shares |
| GOLDMAN SACHS GROUP INC | $567,539 | 1,329,754 | 0.78% | Shares |
| PANAGORA ASSET MANAGEMENT INC | $547,071 | 1,281,796 | 0.75% | Shares |
| NORTHERN TRUST CORP | $522,181 | 1,223,480 | 0.72% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $519,613 | 1,217,463 | 0.71% | Shares |
| Qube Research & Technologies Ltd | $435,802 | 1,021,092 | 0.60% | Shares |
| Caption Management, LLC | $426,800 | 1,000,000 | 0.59% | Shares |
| CM Management, LLC | $426,800 | 1,000,000 | 0.59% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $296,270 | 694,165 | 0.41% | Shares |
| ALLIANCEBERNSTEIN L.P. | $239,958 | 299,910 | 0.33% | Shares |
| Stonepine Capital Management, LLC | $209,468 | 490,787 | 0.29% | Shares |
| NEXPOINT ASSET MANAGEMENT, L.P. | $203,050 | 475,750 | 0.28% | Shares |
| DIADEMA PARTNERS LP | $195,783 | 458,723 | 0.27% | Shares |
| Invesco Ltd. | $173,565 | 406,668 | 0.24% | Shares |
| Xcelsior Advisor Partners LLC | $173,186 | 405,777 | 0.24% | Shares |
| Bank of New York Mellon Corp | $168,944 | 395,838 | 0.23% | Shares |
| Apeiron RIA LLC | $158,163 | 370,579 | 0.22% | Shares |
| Squarepoint Ops LLC | $137,078 | 321,177 | 0.19% | Shares |
| Glenmede Investment Management, LP | $132,710 | 105,326 | 0.18% | Shares |
| TWO SIGMA INVESTMENTS, LP | $113,663 | 266,314 | 0.16% | Shares |
| FMR LLC | $96,800 | 226,803 | 0.13% | Shares |
| Nuveen, LLC | $94,659 | 221,787 | 0.13% | Shares |
| Abel Hall, LLC | $90,987 | 213,185 | 0.12% | Shares |
| CAROLINAS WEALTH CONSULTING LLC | $90,983 | 41,356 | 0.12% | Shares |
| Horan Securities, Inc. | $86,091 | 41,590 | 0.12% | Shares |
| RHUMBLINE ADVISERS | $83,482 | 195,537 | 0.11% | Shares |
| Cutter & CO Brokerage, Inc. | $80,223 | 36,465 | 0.11% | Shares |
| Quinn Opportunity Partners LLC | $74,837 | 175,344 | 0.10% | Shares |
| Integrated Wealth Concepts LLC | $68,287 | 159,997 | 0.09% | Shares |
| RAYMOND JAMES FINANCIAL INC | $67,510 | 158,177 | 0.09% | Shares |
| WELLS FARGO & COMPANY/MN | $65,267 | 152,923 | 0.09% | Shares |
| DLK Investment Management, LLC | $62,615 | 17,890 | 0.09% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $58,500 | 137,067 | 0.08% | Shares |
| D. E. Shaw & Co., Inc. | $51,402 | 120,435 | 0.07% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $51,341 | 120,293 | 0.07% | Shares |
| Persistent Asset Partners Ltd | $49,974 | 117,090 | 0.07% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $48,289 | 112,300 | 0.07% | Call option |
| MORGAN STANLEY | $47,673 | 111,698 | 0.07% | Shares |
| BANK OF AMERICA CORP /DE/ | $46,165 | 108,369 | 0.06% | Shares |
| Redwood Family Wealth LLC | $45,015 | 105,472 | 0.06% | Shares |
| Biltmore Family Office, LLC | $42,680 | 100,000 | 0.06% | Shares |
| DEUTSCHE BANK AG\ | $41,409 | 96,300 | 0.06% | Shares |
| IEQ CAPITAL, LLC | $41,234 | 96,612 | 0.06% | Shares |
| BARCLAYS PLC | $38,848 | 91,022 | 0.05% | Shares |
| SEARLE & CO. | $36,812 | 86,250 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $35,764 | 83,756 | 0.05% | Shares |
| Russell Investments Group, Ltd. | $34,675 | 81,246 | 0.05% | Shares |
| JPMORGAN CHASE & CO | $32,953 | 75,665 | 0.05% | Shares |
| CITIGROUP INC | $31,985 | 74,940 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $31,406 | 73,585 | 0.04% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $29,147 | 68,291 | 0.04% | Shares |
| LPL Financial LLC | $26,083 | 61,112 | 0.04% | Shares |
| Cerity Partners LLC | $25,754 | 60,341 | 0.04% | Shares |
| COMMONWEALTH EQUITY SERVICES, LLC | $25,254 | 59,176 | 0.03% | Shares |
| Anfield Capital Management, LLC | $24,003 | 30,000 | 0.03% | Shares |
| Mariner, LLC | $23,896 | 55,972 | 0.03% | Shares |
| NICOLET ADVISORY SERVICES, LLC | $23,840 | 16,000 | 0.03% | Shares |
| Chicago Partners Investment Group LLC | $23,526 | 51,254 | 0.03% | Shares |
| CWM, LLC | $23,115 | 28,890 | 0.03% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $22,000 | 51,547 | 0.03% | Shares |
| R Squared Ltd | $19,935 | 46,708 | 0.03% | Shares |
| Centiva Capital, LP | $19,422 | 45,507 | 0.03% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $17,990 | 42,150 | 0.02% | Shares |
| HORAN Wealth, LLC | $17,751 | 41,590 | 0.02% | Shares |
| Prospera Financial Services Inc | $17,308 | 40,565 | 0.02% | Shares |
| Cornerstone Select Advisors, LLC | $17,057 | 39,964 | 0.02% | Shares |
| NEUBERGER BERMAN GROUP LLC | $16,647 | 38,987 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $16,369 | 38,352 | 0.02% | Shares |
| GROUP ONE TRADING LLC | $16,196 | 37,947 | 0.02% | Shares |
| Creative Planning | $15,306 | 35,862 | 0.02% | Shares |
| Tower Research Capital LLC (TRC) | $15,180 | 35,567 | 0.02% | Shares |
| HSBC HOLDINGS PLC | $14,464 | 33,381 | 0.02% | Shares |
| DDFG, Inc | $14,043 | 32,903 | 0.02% | Shares |
| Concurrent Investment Advisors, LLC | $13,625 | 31,923 | 0.02% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $13,425 | 32,397 | 0.02% | Shares |
| CIBC WORLD MARKETS CORP | $13,215 | 10,165 | 0.02% | Shares |
| Skopos Labs, Inc. | $12,744 | 15,927 | 0.02% | Shares |
| CoreCap Advisors, LLC | $12,125 | 28,409 | 0.02% | Shares |
| Vanguard Personalized Indexing Management, LLC | $11,641 | 27,276 | 0.02% | Shares |
| DIVERSIFIED TRUST CO | $11,306 | 26,492 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $11,139 | 26,100 | 0.02% | Call option |
| Pallas Capital Advisors LLC | $10,968 | 25,699 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $10,957 | 25,672 | 0.02% | Shares |
| TopTier Wealth Management, LLC | $10,819 | 25,350 | 0.01% | Shares |
| Parkway Wealth Management Group, LLC | $10,670 | 25,000 | 0.01% | Shares |
| HighTower Advisors, LLC | $10,507 | 24,617 | 0.01% | Shares |
| &PARTNERS | $10,086 | 23,632 | 0.01% | Shares |
| PRUDENTIAL FINANCIAL INC | $10,028 | 23,495 | 0.01% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $9,606 | 22,507 | 0.01% | Shares |
| CITADEL ADVISORS LLC | $8,963 | 21,000 | 0.01% | Put option |
| ProShare Advisors LLC | $8,928 | 20,918 | 0.01% | Shares |
| TWO SIGMA SECURITIES, LLC | $8,858 | 20,754 | 0.01% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $8,632 | 20,226 | 0.01% | Shares |
| Argent Advisors, Inc. | $8,536 | 20,000 | 0.01% | Shares |
| PKS Advisory Services, LLC | $8,536 | 20,000 | 0.01% | Shares |
| Advisory Services Network, LLC | $8,357 | 19,580 | 0.01% | Shares |
| Capital Investment Counsel, Inc | $7,821 | 18,325 | 0.01% | Shares |
| Cetera Investment Advisers | $7,623 | 17,861 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $6,666 | 15,618 | 0.01% | Shares |
| COMERICA BANK | $6,436 | 4,951 | 0.01% | Shares |
| J.W. COLE ADVISORS, INC. | $6,402 | 15,000 | 0.01% | Shares |
| Allworth Financial LP | $6,121 | 14,341 | 0.01% | Shares |
| Pekin Hardy Strauss, Inc. | $5,972 | 13,992 | 0.01% | Shares |
| Legal & General Group Plc | $5,945 | 13,930 | 0.01% | Shares |
| XPONANCE LLC | $5,880 | 13,778 | 0.01% | Shares |
| HB Wealth Management, LLC | $5,797 | 13,583 | 0.01% | Shares |
| SEI INVESTMENTS CO | $5,414 | 12,685 | 0.01% | Shares |
| HARBOUR INVESTMENTS, INC. | $5,277 | 12,365 | 0.01% | Shares |
| B. Riley Wealth Advisors, Inc. | $5,271 | 12,103 | 0.01% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $5,187 | 12,062 | 0.01% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $5,153 | 12,074 | 0.01% | Shares |
| Spectrum Investment Advisors, Inc. | $5,007 | 11,731 | 0.01% | Shares |
| JMN Financial LLC | $4,810 | 11,269 | 0.01% | Shares |
| BRIGHTON JONES LLC | $4,752 | 11,133 | 0.01% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,644 | 10,800 | 0.01% | Put option |
| Venturi Wealth Management, LLC | $4,482 | 10,500 | 0.01% | Shares |
| SIMPLEX TRADING, LLC | $3,108 | 7,283 | 0.00% | Shares |
| Arax Advisory Partners | $2,941 | 6,890 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $2,106 | 4,934 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $2,000 | 5,460 | 0.00% | Shares |
| Global Retirement Partners, LLC | $1,715 | 4,018 | 0.00% | Shares |
| Essential Partners LLC | $1,711 | 4,008 | 0.00% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1,662 | 2,078 | 0.00% | Shares |
| Clearstead Advisors, LLC | $1,494 | 3,498 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $918 | 2,152 | 0.00% | Shares |
| Optiver Holding B.V. | $728 | 1,706 | 0.00% | Shares |
| N.E.W. Advisory Services LLC | $691 | 1,619 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $445 | 1,042,892 | 0.00% | Shares |
| Winch Advisory Services, LLC | $427 | 1,000 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $427 | 1,000 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $420 | 984 | 0.00% | Shares |
| Fortitude Family Office, LLC | $379 | 888 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $369 | 861 | 0.00% | Shares |
| Sterling Capital Management LLC | $344 | 807 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $240 | 560 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $221 | 518 | 0.00% | Shares |
| New England Capital Financial Advisors LLC | $203 | 475 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $178 | 415 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $151 | 354 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $141 | 331 | 0.00% | Shares |
| Wealth Enhancement Trust Services, Inc. | $137 | 320 | 0.00% | Shares |
| Virtu Financial LLC | $121 | 283,239 | 0.00% | Shares |
| Parallel Advisors, LLC | $85 | 200 | 0.00% | Shares |
| Pinnacle Wealth Planning Services, Inc. | $76 | 178 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $75 | 175 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $65 | 153,011 | 0.00% | Shares |
| IFP Advisors, Inc | $51 | 120 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $48 | 111,504 | 0.00% | Shares |
| AdvisorNet Financial, Inc | $47 | 110 | 0.00% | Shares |
| HighMark Wealth Management LLC | $42 | 100 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $30 | 37 | 0.00% | Shares |
| King Wealth Management Group | $14 | 32,799 | 0.00% | Shares |
| Cambridge Investment Research Advisors, Inc. | $12 | 27,995 | 0.00% | Shares |
| HRT FINANCIAL LP | $11 | 27,024 | 0.00% | Shares |
| INGALLS & SNYDER LLC | $5 | 11,415 | 0.00% | Shares |
| JTC Employer Solutions Trustee Ltd | $3 | 6,500 | 0.00% | Shares |
| Forum Finance Group S.A. | $3 | 8,500 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $3 | 6 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $0 | 1 | 0.00% | Shares |