IVA — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Caligan Partners LP | $30,856,862 | 8,163,191 | 9.39% | Shares |
| SAMSARA BIOCAPITAL, LLC | $23,869,963 | 6,314,805 | 7.26% | Shares |
| Paradigm Biocapital Advisors LP | $15,120,000 | 4,000,000 | 4.60% | Shares |
| ANDERA PARTNERS | $13,733,424 | 3,633,181 | 4.18% | Shares |
| ADAR1 Capital Management, LLC | $13,633,160 | 3,606,656 | 4.15% | Shares |
| MILLENNIUM MANAGEMENT LLC | $13,276,018 | 3,512,174 | 4.04% | Shares |
| SymBiosis Capital Partners, LLC | $13,064,700 | 2,354,000 | 3.98% | Shares |
| Nantahala Capital Management, LLC | $10,154,566 | 2,686,393 | 3.09% | Shares |
| Trails Edge Capital Partners, LP | $10,047,228 | 2,657,997 | 3.06% | Shares |
| FRANKLIN RESOURCES INC | $9,989,070 | 2,642,611 | 3.04% | Shares |
| Squadron Capital Management LLC | $9,204,300 | 2,435,000 | 2.80% | Shares |
| Woodline Partners LP | $8,781,503 | 2,323,149 | 2.67% | Shares |
| Aberdeen Group plc | $8,723,382 | 2,307,773 | 2.65% | Shares |
| UBS Group AG | $8,713,626 | 2,305,192 | 2.65% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $7,574,296 | 2,003,782 | 2.30% | Shares |
| Patient Square Capital LP | $7,435,906 | 1,967,171 | 2.26% | Shares |
| NEXTBio Capital Management LP | $6,758,580 | 1,787,984 | 2.06% | Shares |
| CITADEL ADVISORS LLC | $6,745,659 | 1,784,566 | 2.05% | Shares |
| AMERIPRISE FINANCIAL INC | $6,415,219 | 1,697,148 | 1.95% | Shares |
| Point72 Asset Management, L.P. | $6,361,785 | 1,683,012 | 1.94% | Shares |
| Integral Health Asset Management, LLC | $5,745,600 | 1,520,000 | 1.75% | Shares |
| Yu Fan | $5,670,000 | 1,500,000 | 1.73% | Shares |
| NEA Management Company, LLC | $5,528,575 | 1,462,586 | 1.68% | Shares |
| STEMPOINT CAPITAL LP | $5,391,490 | 1,426,320 | 1.64% | Shares |
| Propel Bio Management, LLC | $4,842,981 | 1,281,212 | 1.47% | Shares |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4,800,600 | 1,270,000 | 1.46% | Shares |
| JPMORGAN CHASE & CO | $4,647,305 | 1,309,100 | 1.41% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4,233,600 | 1,120,000 | 1.29% | Shares |
| Ikarian Capital, LLC | $4,152,521 | 1,129,101 | 1.26% | Shares |
| Polar Capital Holdings Plc | $4,060,529 | 1,074,214 | 1.24% | Shares |
| MARSHALL WACE, LLP | $3,651,131 | 965,907 | 1.11% | Shares |
| Alyeska Investment Group, L.P. | $3,436,020 | 909,000 | 1.05% | Shares |
| MORGAN STANLEY | $3,408,199 | 901,640 | 1.04% | Shares |
| JANE STREET GROUP, LLC | $3,407,175 | 901,369 | 1.04% | Shares |
| HighVista Strategies LLC | $3,142,851 | 831,442 | 0.96% | Shares |
| Deep Track Capital, LP | $3,024,000 | 800,000 | 0.92% | Shares |
| TWO SIGMA INVESTMENTS, LP | $2,752,260 | 728,111 | 0.84% | Shares |
| DIADEMA PARTNERS LP | $2,725,718 | 740,786 | 0.83% | Shares |
| BVF INC/IL | $2,593,231 | 686,040 | 0.79% | Shares |
| FMR LLC | $2,590,812 | 685,400 | 0.79% | Shares |
| Ally Bridge Group (NY) LLC | $2,399,544 | 634,800 | 0.73% | Shares |
| Qube Research & Technologies Ltd | $1,502,769 | 397,558 | 0.46% | Shares |
| J. Goldman & Co LP | $1,275,750 | 337,500 | 0.39% | Shares |
| Simplify Asset Management Inc. | $1,184,966 | 313,483 | 0.36% | Shares |
| Artisan Partners Limited Partnership | $996,174 | 263,538 | 0.30% | Shares |
| Ghisallo Capital Management LLC | $945,000 | 250,000 | 0.29% | Shares |
| Burkehill Global Management, LP | $850,500 | 225,000 | 0.26% | Shares |
| SEVEN GRAND MANAGERS, LLC | $850,500 | 225,000 | 0.26% | Shares |
| GOLDMAN SACHS GROUP INC | $848,606 | 224,499 | 0.26% | Shares |
| XTX Topco Ltd | $809,986 | 214,282 | 0.25% | Shares |
| Persistent Asset Partners Ltd | $790,708 | 209,182 | 0.24% | Shares |
| Quadrature Capital Ltd | $783,148 | 207,182 | 0.24% | Shares |
| Seven Fleet Capital Management LP | $756,533 | 200,141 | 0.23% | Shares |
| BANK OF AMERICA CORP /DE/ | $574,247 | 151,917 | 0.17% | Shares |
| Balyasny Asset Management L.P. | $545,004 | 144,181 | 0.17% | Shares |
| Walleye Capital LLC | $512,749 | 135,648 | 0.16% | Shares |
| Hudson Bay Capital Management LP | $434,700 | 115,000 | 0.13% | Shares |
| Rathbones Group PLC | $378,000 | 100,000 | 0.12% | Shares |
| COMMONWEALTH EQUITY SERVICES, LLC | $317,500 | 83,996 | 0.10% | Shares |
| Engineers Gate Manager LP | $268,818 | 71,116 | 0.08% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $157,922 | 36,726 | 0.05% | Shares |
| Jefferies Financial Group Inc. | $151,200 | 40,000 | 0.05% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $129,861 | 34,355 | 0.04% | Shares |
| R Squared Ltd | $113,090 | 29,918 | 0.03% | Shares |
| Quaker Wealth Management, LLC | $94,349 | 24,960 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $92,485 | 24,467 | 0.03% | Shares |
| Shay Capital LLC | $82,672 | 21,871 | 0.03% | Shares |
| China Universal Asset Management Co., Ltd. | $81,648 | 21,600 | 0.02% | Shares |
| NewEdge Advisors, LLC | $75,895 | 20,078 | 0.02% | Shares |
| Cerity Partners LLC | $75,600 | 20,000 | 0.02% | Shares |
| ROYAL BANK OF CANADA | $60,000 | 15,741 | 0.02% | Shares |
| Ground Swell Capital, LLC | $48,395 | 12,803 | 0.01% | Shares |
| BLAIR WILLIAM & CO/IL | $37,800 | 10,000 | 0.01% | Shares |
| Frec Markets, Inc. | $37,800 | 10,000 | 0.01% | Shares |
| CITIGROUP INC | $24,993 | 6,612 | 0.01% | Shares |
| GAMMA Investing LLC | $18,976 | 5,020 | 0.01% | Shares |
| RHUMBLINE ADVISERS | $17,656 | 4,672 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $6,804 | 1,800 | 0.00% | Shares |
| BARCLAYS PLC | $6,732 | 1,781 | 0.00% | Shares |
| Stone House Investment Management, LLC | $5,530 | 1,463 | 0.00% | Shares |
| SYQUANT CAPITAL SAS | $3,452 | 913,135 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $1,164 | 308 | 0.00% | Shares |
| Atlantic Union Bankshares Corp | $1,134 | 300 | 0.00% | Shares |
| Larson Financial Group LLC | $851 | 225 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $586 | 155 | 0.00% | Shares |
| HRT FINANCIAL LP | $468 | 123,953 | 0.00% | Shares |
| Bell Investment Advisors, Inc | $288 | 76 | 0.00% | Shares |
| Arax Advisory Partners | $193 | 51 | 0.00% | Shares |
| Covestor Ltd | $2 | 402 | 0.00% | Shares |