SAMSARA BIOCAPITAL, LLC
CIK 1744967 · View on SEC EDGAR ↗
- Portfolio value
- $1.2B
- Positions
- 24
- As of
- June 30, 2026
#2,135 of 9,443 by 13F value · top 22.6%
Portfolio value QoQ: +18.3% 13F does not disclose cash
- Top 10 holdings weight
- 90.48%
- Top 25 holdings weight
- 100.00%
- Positions above 1%
- 12
- Effective number of positions
- 6.5
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q2 2026: 1.97% Est. buys $102,879,583 · sells $22,104,240
Median holding: 3.0 quarters Tracked Q4 2024–Q2 2026 · 40.7% still held
- New positions
- 4
- Increased
- 2
- Decreased
- 5
- Closed
- 2
On this page
- Performance vs S&P How this manager's 13F portfolio performed against the S&P 500.
- Sector breakdown How the portfolio splits across market sectors.
- Portfolio Every stock this institution reports holding, from its latest 13F.
- Biggest new bets Brand-new positions opened in the latest quarter.
- Top moves The biggest position increases and decreases this quarter.
- Exited positions Positions the manager fully sold out of last quarter.
Performance vs S&P 500
Annualized: +27.2% · S&P 500: +18.0%
Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.
Priceable coverage: 97.2% · Options excluded: 0.0%
Sector breakdown
Healthcare
88.3%
Other/Unmapped
11.7%
Full portfolio 24 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| SRRK Scholar Rock Holding Corporation - Common Stock | $379,370,860 | 31.16% | 6,897,652 | $40,282,288 | |||
| ALMS Alumis Inc. - Common Stock | $178,554,463 | 14.67% | 6,345,219 | $38,769,288 | |||
| MLYS Mineralys Therapeutics, Inc. - Common Stock | $158,400,066 | 13.01% | 5,871,018 | $-645,812 | |||
| SEPN Septerna, Inc. - Common Stock | $105,464,297 | 8.66% | 3,149,128 | $29,790,751 | |||
| Unknown issuer (CUSIP: 010911105) | $67,191,598 | 5.52% | 2,480,310 | Up ×1 | |||
| NGNE Neurogene Inc. - Common Stock | $54,003,644 | 4.44% | 1,717,127 | $19,386,364 | |||
| KLRS Kalaris Therapeutics, Inc. - Common Stock | $52,426,382 | 4.31% | 12,881,175 | $-22,284,045 | Down ×1 | ||
| SGP SpyGlass Pharma, Inc. - Common Stock | $46,967,554 | 3.86% | 2,109,953 | $-7,701,328 | |||
| STRO Sutro Biopharma, Inc. - Common Stock | $35,287,350 | 2.90% | 1,062,872 | $8,811,208 | |||
| IVA Inventiva S.A. - American Depository Shares | $23,869,963 | 1.96% | 6,314,805 | $-4,961,205 | Up ×1 | ||
| JBIO Jade Biosciences, Inc. - Common Stock | $16,359,186 | 1.34% | 736,237 | $2,747,574 | Down ×1 | ||
| Unknown issuer (CUSIP: 698955101) | $15,218,924 | 1.25% | 556,044 | Up ×1 | |||
| VTVT vTv Therapeutics Inc. - Class A Common Stock | $11,238,374 | 0.92% | 298,496 | $-599,977 | |||
| AQST Aquestive Therapeutics, Inc. - Common Stock | $10,400,000 | 0.85% | 2,500,000 | $25,000 | |||
| NKTX Nkarta, Inc. - Common Stock | $9,926,695 | 0.82% | 3,507,666 | $2,525,520 | |||
| ARTV Artiva Biotherapeutics, Inc. - Common Stock | $9,262,152 | 0.76% | 954,861 | ||||
| RANI Rani Therapeutics Holdings, Inc. - Class A Common Stock | $7,884,709 | 0.65% | 10,369,159 | $1,638,909 | Up ×1 | ||
| AGMB AgomAb Therapeutics NV - ADRs representing one common share. | $7,788,000 | 0.64% | 600,000 | $1,494,000 | |||
| ABVX Abivax SA - American Depositary Shares | $7,341,960 | 0.60% | 55,095 | $1,041,666 | Down ×2 | ||
| XFOR X4 Pharmaceuticals, Inc. - Common Stock | $6,517,391 | 0.54% | 1,395,587 | $-1,051,107 | Down ×2 | ||
| Unknown issuer (CUSIP: 29014R301) | $5,552,000 | 0.46% | 400,000 | Up ×1 | |||
| CHRS Coherus Oncology, Inc. - Common Stock | $4,799,999 | 0.39% | 3,428,571 | $-994,286 | |||
| UPB Upstream Bio, Inc. - Common Stock | $2,447,722 | 0.20% | 353,717 | $-4,176,701 | Down ×1 | ||
| GOSS Gossamer Bio, Inc. - Common Stock | $1,188,833 | 0.10% | 7,222,559 | $-1,183,778 | |||
| No matches | |||||||
Biggest new bets
New positions opened this quarter, largest first.
| Security | Value | Shares | % of portfolio |
|---|---|---|---|
| Unknown issuer (CUSIP: 010911105) | $67,191,598 | 2,480,310 | 5.52% |
| Unknown issuer (CUSIP: 698955101) | $15,218,924 | 556,044 | 1.25% |
| ARTV | $9,262,152 | 954,861 | 0.76% |
| Unknown issuer (CUSIP: 29014R301) | $5,552,000 | 400,000 | 0.46% |
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| SRRK | Price move only | +0 | +$40.3M |
| ALMS | Price move only | +0 | +$38.8M |
| SEPN | Price move only | +0 | +$29.8M |
| KLRS | Trimmed | -67K | -$22.3M |
| NGNE | Price move only | +0 | +$19.4M |
| STRO | Price move only | +0 | +$8.8M |
| SGP | Price move only | +0 | -$7.7M |
| IVA | Bought more | +1.1M | -$5.0M |
| UPB | Trimmed | -382K | -$4.2M |
| JBIO | Trimmed | -233K | +$2.7M |
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| CRGX | Sept. 30, 2025 | 4,415,689 | $18,192,639 | No longer tracked |
| LENZ | Dec. 31, 2025 | 343,012 | $15,977,499 | -70.1% |
| JSPR | March 31, 2025 | 584,642 | $12,499,646 | -83.4% |
| AVDL | Dec. 31, 2025 | 675,504 | $10,314,946 | No longer tracked |
| ACLX | June 30, 2026 | 60,873 | $6,989,438 | No longer tracked |
| SLRN | June 30, 2025 | 2,523,022 | $6,231,864 | No longer tracked |
| ACRS | March 31, 2025 | 2,385,060 | $5,914,949 | 316.5% |
| PVLA | June 30, 2026 | 38,432 | $4,790,549 | -5.2% |
| CLYM | March 31, 2025 | 2,609,114 | $4,696,405 | 1306.5% |
| VRNA | March 31, 2025 | 97,625 | $4,533,705 | No longer tracked |
| AURA | Dec. 31, 2025 | 584,849 | $3,614,367 | 44.4% |
| ZYME | Dec. 31, 2025 | 207,901 | $3,550,949 | 2.7% |
| OKUR | June 30, 2025 | 824,155 | $3,543,867 | 66.1% |
| SRZN | Dec. 31, 2025 | 241,400 | $3,110,439 | 5.2% |
| RYTM | Dec. 31, 2025 | 30,285 | $3,058,482 | 2.6% |
| ABVX | June 30, 2025 | 425,000 | $2,656,250 | 1461.4% |
| DAWN | March 31, 2025 | 147,319 | $1,866,532 | No longer tracked |
| INZY | June 30, 2025 | 1,562,500 | $1,421,875 | No longer tracked |
| IMTX | March 31, 2025 | 198,000 | $1,407,780 | 95.3% |
| TNGX | Sept. 30, 2025 | 210,000 | $1,075,200 | 186.1% |
| TERN | Dec. 31, 2025 | 135,573 | $1,018,153 | No longer tracked |
| CTNM | March 31, 2026 | 72,245 | $825,760 | 22.5% |
| PRME | June 30, 2025 | 405,228 | $806,404 | 33.8% |
| HLVX | Sept. 30, 2025 | 399,637 | $795,278 | No longer tracked |
| CYPH | June 30, 2025 | 2,442,352 | $745,162 | 341.1% |
| JANX | March 31, 2025 | 11,263 | $603,021 | -34.9% |
| ARTV | Sept. 30, 2025 | 291,666 | $440,416 | 295.8% |
| CRIS | June 30, 2025 | 185,943 | $390,480 | -31.0% |
| BOLT | Dec. 31, 2025 | 48,830 | $259,776 | -39.3% |
| LYRAXXXX | June 30, 2025 | 1,390,130 | $175,573 | No longer tracked |
| KRON | June 30, 2025 | 78,131 | $64,458 | No longer tracked |
| NUVBWS | March 31, 2026 | 124,119 | $40,959 | No longer tracked |
| ALLK | June 30, 2025 | 172,089 | $39,167 | No longer tracked |
| ALVR | March 31, 2025 | 82,336 | $34,581 | No longer tracked |
| SRZNW | Dec. 31, 2025 | 99,999 | $1,780 | No longer tracked |