KROS Keros Therapeutics, Inc. - common stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$10.86
Price · Aug 19, 2026
Fundamentals as of Aug 3, 2026

KROS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$10.86
Market Cap
$212M
P/E (TTM)
4.7
EPS (TTM)
$2.30
Revenue (TTM)
$244M
Div Yield
ROE
17.2%
Debt/Equity
52W Range
$10 – $23

KROS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $244M
7-point trend, +2338.6%
2019-12-31 2025-12-31
EPS $2.30
6-point trend, +178.5%
2020-12-31 2025-12-31
Free Cash Flow $106M
6-point trend, +384.9%
2020-12-31 2025-12-31
Margins 35.7%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
KROS
Peer Median
P/E (TTM)
5-point trend, +138.1%
4.7
1.2
P/S (TTM)
3-point trend, -97.7%
0.9
6.3
P/B
5-point trend, -77.2%
0.7
1.6
Price / FCF
5-point trend, +116.9%
2.0

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
KROS
Peer Median
Operating Margin
4-point trend, +109.9%
27.7%
Net Profit Margin
4-point trend, +112.2%
35.7%
-312.6%
ROA
5-point trend, +181.5%
18.2%
-56.8%
ROE
5-point trend, +167.7%
17.2%
-83.3%
ROIC
5-point trend, +188.0%
21.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
KROS
Peer Median
Current Ratio
5-point trend, -27.2%
15.5
8.5
Quick Ratio
5-point trend, -31.9%
14.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
KROS
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
KROS
Peer Median
EPS (Diluted)
5-point trend, +191.3%
$2.30

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
KROS
Peer Median

KROS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 3 21.4%
  • Buy 6 42.9%
  • Hold 5 35.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

6 analysts · 2026-08-18
Median target $19.00 +75.0%
Mean target $19.83 +82.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.78%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.45 $-1.37 -0.08%
March 31, 2026 $-1.21 $-1.04 -0.17%
Dec. 31, 2025 $-0.86 $-0.64 -0.22%
Sept. 30, 2025 $-0.18 $-1.07 0.89%
June 30, 2025 $-0.76 $-1.15 0.39%
March 31, 2025 $3.62 $-0.25 3.9%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
KROS $398M 8.9 35.7% 17.2%
IMUX -0.9
TNXP $200M -1.1 29.8% -946.2% -60.0%
NBP
ABOS $128M -1.1 -129.4%
KRRO $75M -0.6 181.5% -1834.5% -140.8%
WHWK $114M -7.3 -72.5% -288.3% -13.4%
PEPG $448M -3.1 -82.0%
CHRS $172M 1.0 59.8% 398.4% 185.8%
HUMA
CRBP $143M -1.4 -60.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for KROS
Metric Trend 2025202420232022202120202019
Revenue 7-point trend, +2338.6% $244M $0 $151.0K $0 $20M $0 $10M
R&D Expense 7-point trend, +646.0% $130M $174M $135M $87M $55M $34M $17M
SG&A Expense 7-point trend, +1371.4% $47M $41M $35M $28M $21M $13M $3M
Operating Expenses 7-point trend, +758.3% $176M $214M $170M $115M $76M $47M $21M
Operating Income 7-point trend, +739.7% $68M $-211M $-170M $-115M $-56M $-47M $-11M
Other Non-op 7-point trend, -323.7% $-539.0K $-954.0K $-206.0K $-613.0K $-383.0K $160.0K $241.0K
Pretax Income 7-point trend, +844.9% $92M $-187M $-153M $-105M $-57M $-46M $-12M
Income Tax 7-point trend, +4883000.00 $5M $300.0K $0 $0 $2M $-172.0K $0
Net Income 7-point trend, +805.4% $87M $-187M $-153M $-105M $-59M $-45M $-12M
EPS (Basic) 6-point trend, +179.9% $2.34 $-5.00 $-5.20 $-4.15 $-2.52 $-2.93 ·
EPS (Diluted) 6-point trend, +178.5% $2.30 $-5.00 $-5.20 $-4.15 $-2.52 $-2.93 ·
Shares (Basic) 6-point trend, +140.0% 37,221,211 37,437,652 29,447,119 25,241,030 23,333,914 15,506,397 ·
Shares (Diluted) 6-point trend, +144.2% 37,859,106 37,437,652 29,447,119 25,241,030 23,333,914 15,506,397 ·
EBITDA 6-point trend, +244.8% $68M $-211M $-170M $-115M $-56M $-47M ·
Balance Sheet 23
Annual Balance Sheet data for KROS
Metric Trend 2025202420232022202120202019
Cash & Equivalents 7-point trend, +3994.2% $287M $560M $331M $279M $230M $266M $7M
Receivables 6-point trend, +3567000.00 $4M $3M $143.0K $0 $18M $0 ·
Prepaid Expense 7-point trend, +5727.3% $22M $26M $16M $7M $3M $2M $381.0K
Other Current Assets 7-point trend, +1014.9% $2M $1M $1M $276.0K $210.0K $160.0K $215.0K
Current Assets 7-point trend, +3433.5% $315M $589M $347M $286M $251M $268M $9M
PP&E (Net) 7-point trend, +506.9% $4M $4M $4M $2M $1M $724.0K $708.0K
PP&E (Gross) 7-point trend, +652.1% $9M $7M $6M $3M $2M $1M $1M
Accum. Depreciation 7-point trend, +879.0% $4M $3M $2M $1M $846.0K $721.0K $453.0K
Other Non-current Assets 6-point trend, +0.00 $0 $2M $2M $2M $82.0K $0 ·
Total Assets 7-point trend, +2985.5% $338M $616M $370M $307M $255M $269M $11M
Accounts Payable 7-point trend, -5.8% $2M $5M $5M $3M $4M $2M $2M
Accrued Liabilities 7-point trend, +693.2% $16M $21M $18M $13M $7M $5M $2M
Current Liabilities 7-point trend, +355.1% $20M $27M $24M $17M $12M $7M $4M
Capital Leases 7-point trend, +1510.1% $14M $17M $13M $13M $231.0K $476.0K $899.0K
Other Non-current Liabilities 3-point trend, -100.0% · · · · $0 $62.0K $119.0K
Total Liabilities 7-point trend, +233.5% $35M $44M $38M $29M $12M $8M $10M
Common Stock 7-point trend, +300.0% $4.0K $4.0K $3.0K $2.0K $2.0K $2.0K $1.0K
Paid-in Capital 7-point trend, +575984.2% $1.17B $1.14B $714M $506M $367M $327M $203.0K
Retained Earnings 7-point trend, -2351.7% $-482M $-569M $-381M $-228M $-124M $-65M $-20M
Treasury Stock 2-point trend, +384558000.00 $385M $0 · · · · ·
Stockholders' Equity 7-point trend, +1658.8% $303M $572M $332M $277M $243M $262M $-19M
Liabilities + Equity 7-point trend, +2985.5% $338M $616M $370M $307M $255M $269M $11M
Shares Outstanding 7-point trend, +704.4% 19,543,706 40,554,705 31,841,084 27,543,453 23,974,834 23,192,866 2,429,705
Cash Flow 12
Annual Cash Flow data for KROS
Metric Trend 2025202420232022202120202019
Stock-based Comp 7-point trend, +48537.3% $29M $35M $29M $19M $12M $4M $59.0K
Deferred Tax Flat — no change across 7 periods $0 $0 $0 $0 $0 $0 $0
Operating Cash Flow 7-point trend, +772.0% $108M $-161M $-125M $-70M $-62M $-37M $-16M
CapEx 7-point trend, +472.3% $2M $2M $2M $1M $1M $294.0K $271.0K
Investing Cash Flow 7-point trend, -472.3% $-2M $-2M $-2M $-1M $-1M $-294.0K $-271.0K
Stock Issued 2-point trend, +140530000.00 · · · · · $141M $0
Stock Repurchased 2-point trend, +375000000.00 $375M $0 · · · · ·
Net Stock Activity 2-point trend, -366.8% $-375M · · · · $141M ·
Financing Cash Flow 7-point trend, -2703457.1% $-378M $392M $179M $120M $29M $296M $14.0K
Net Change in Cash 7-point trend, -1576.5% $-273M $229M $52M $49M $-35M $259M $-16M
Taxes Paid 4-point trend, +2691.0% $7M $0 · · · $0 $256.0K
Free Cash Flow 6-point trend, +384.9% $106M $-163M $-127M $-71M $-63M $-37M ·
Profitability 7
Annual Profitability data for KROS
Metric Trend 2025202420232022202120202019
Operating Margin 4-point trend, +109.9% 27.7% -5939.0% -112543.7% · -280.5% · ·
Net Margin 4-point trend, +112.2% 35.7% -5277.6% -101319.2% · -292.3% · ·
Pretax Margin 4-point trend, +113.3% 37.7% -5269.1% -101319.2% · -282.2% · ·
EBITDA Margin 4-point trend, +109.9% 27.7% -5939.0% -112543.7% · -280.5% · ·
ROA 6-point trend, +156.4% 18.2% -38.0% -45.2% -37.2% -22.4% -32.4% ·
ROE 6-point trend, +174.5% 17.2% -33.9% -48.7% -40.4% -25.4% -23.1% ·
ROIC 6-point trend, +218.9% 21.1% -37.0% -51.1% -41.4% -24.0% -17.8% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for KROS
Metric Trend 2025202420232022202120202019
Current Ratio 6-point trend, -58.5% 15.5 21.5 14.2 17.3 21.2 37.3 ·
Quick Ratio 6-point trend, -61.5% 14.3 20.5 13.6 16.9 20.9 37.0 ·
Efficiency 2
Annual Efficiency data for KROS
Metric Trend 2025202420232022202120202019
Asset Turnover 6-point trend, +0.51 0.5 0.0 0.0 0.0 0.1 0.0 ·
Receivables Turnover 5-point trend, +3361.5% 77.3 2.5 2.1 0.0 2.2 · ·
Per Share 5
Annual Per Share data for KROS
Metric Trend 2025202420232022202120202019
Book Value / Share 6-point trend, +37.4% $15.51 $14.09 $10.43 $10.07 $10.14 $11.28 ·
Revenue / Share 5-point trend, +647.8% $6.44 $0.09 $0.01 $0.00 $0.86 · ·
Cash Flow / Share 5-point trend, +206.6% $2.84 $-4.30 $-4.23 $-2.78 $-2.66 · ·
Cash / Share 6-point trend, +28.3% $14.71 $13.81 $10.40 $10.13 $9.60 $11.46 ·
EPS (TTM) 6-point trend, +178.5% $2.30 $-5.00 $-5.20 $-4.15 $-2.52 $-2.93 ·
Valuation (TTM) 10
Annual Valuation (TTM) data for KROS
Metric Trend 2025202420232022202120202019
Revenue TTM 6-point trend, +243864000.00 $244M $0 $151.0K $0 $20M $0 ·
Net Income TTM 6-point trend, +291.8% $87M $-187M $-153M $-105M $-59M $-45M ·
Market Cap 6-point trend, -75.7% $398M $642M $1.27B $1.32B $1.40B $1.64B ·
P/E 6-point trend, +136.8% 8.9 -3.2 -7.6 -11.6 -23.2 -24.1 ·
P/S 3-point trend, -97.7% 1.6 · 8384.1 · 69.8 · ·
P/B 6-point trend, -79.0% 1.3 1.1 3.8 4.8 5.8 6.3 ·
P / Tangible Book 6-point trend, -79.0% 1.3 1.1 3.8 4.8 5.8 6.3 ·
P / Cash Flow 6-point trend, +108.3% 3.7 -4.0 -10.2 -18.9 -22.6 -44.3 ·
P / FCF 6-point trend, +108.5% 3.8 -3.9 -10.0 -18.5 -22.2 -44.0 ·
Earnings Yield 6-point trend, +372.3% 11.3% -31.6% -13.1% -8.6% -4.3% -4.2% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $244M$0$151.0K$0$20M
Operating Margin % 27.7%-5939.0%-112543.7%-280.5%
Net Income $87M$-187M$-153M$-105M$-59M
Diluted EPS $2.30$-5.00$-5.20$-4.15$-2.52
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 15.521.514.217.321.2
Quick Ratio 14.320.513.616.920.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $106M$-163M$-127M$-71M$-63M

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Institutional owners (13F) 149 filers · $142.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
21 (-5 vs prior Q) 29 (-6 vs prior Q) 42 (-3 vs prior Q) 46 (-8 vs prior Q) +595K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Nantahala Capital Management, LLC $15,091,483 1,410,419 10.60% Shares
VANGUARD CAPITAL MANAGEMENT LLC $8,919,477 833,596 6.26% Shares
ORBIMED ADVISORS LLC $8,122,959 759,155 5.71% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $6,983,195 652,635 4.90% Shares
MACKENZIE FINANCIAL CORP $6,724,287 628,438 4.72% Shares
Madison Avenue Partners, LP $6,704,438 626,583 4.71% Shares
Qube Research & Technologies Ltd $6,514,556 608,837 4.58% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $6,478,262 605,445 4.55% Shares
STATE STREET CORP $5,790,765 541,193 4.07% Shares
GEODE CAPITAL MANAGEMENT, LLC $4,694,194 438,563 3.30% Shares
DIMENSIONAL FUND ADVISORS LP $4,526,357 423,024 3.18% Shares
RENAISSANCE TECHNOLOGIES LLC $3,842,220 359,086 2.70% Shares
TWO SIGMA ADVISERS, LP $3,497,848 171,800 2.46% Shares
CITADEL ADVISORS LLC $3,095,435 289,293 2.17% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $2,835,682 265,017 1.99% Shares
BlackRock, Inc. $2,790,421 260,787 1.96% Shares
ADAR1 Capital Management, LLC $2,640,953 246,818 1.85% Shares
TWO SIGMA INVESTMENTS, LP $2,639,144 246,649 1.85% Shares
VANGUARD GROUP INC $2,594,882 127,450 1.82% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $2,494,973 233,175 1.75% Shares
MILLENNIUM MANAGEMENT LLC $1,977,595 184,822 1.39% Shares
Cubist Systematic Strategies, LLC $1,922,605 121,530 1.35% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,698,218 158,712 1.19% Shares
Man Group plc $1,664,289 155,541 1.17% Shares
VANGUARD FIDUCIARY TRUST CO $1,405,060 131,314 0.99% Shares
Connor, Clark & Lunn Investment Management Ltd. $1,368,370 127,885 0.96% Shares
O'SHAUGHNESSY ASSET MANAGEMENT, LLC $1,352,255 126,379 0.95% Shares
Nebula Research & Development LLC $1,206,920 90,406 0.85% Shares
AMERIPRISE FINANCIAL INC $1,084,360 101,342 0.76% Shares
GOLDMAN SACHS GROUP INC $942,221 88,058 0.66% Shares
AMERICAN CENTURY COMPANIES INC $906,076 84,680 0.64% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $902,781 84,372 0.63% Shares
HSBC HOLDINGS PLC $761,494 69,926 0.53% Shares
MARTINGALE ASSET MANAGEMENT L P $725,418 67,796 0.51% Shares
RBF Capital, LLC $671,960 62,800 0.47% Shares
AlphaQuest LLC $653,352 32,090 0.46% Shares
Bank of New York Mellon Corp $646,869 60,455 0.45% Shares
XTX Topco Ltd $636,982 59,531 0.45% Shares
Jain Global LLC $633,536 59,209 0.44% Shares
PANAGORA ASSET MANAGEMENT INC $599,040 55,985 0.42% Shares
IEQ CAPITAL, LLC $595,723 55,675 0.42% Shares
JANE STREET GROUP, LLC $583,557 54,538 0.41% Shares
Rangeley Capital, LLC $582,080 54,400 0.41% Shares
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO $538,467 50,324 0.38% Shares
BNP PARIBAS FINANCIAL MARKETS $533,406 49,851 0.37% Shares
Y-Intercept (Hong Kong) Ltd $515,483 48,176 0.36% Shares
BARCLAYS PLC $509,576 47,624 0.36% Shares
DEUTSCHE BANK AG\ $500,781 46,802 0.35% Shares
Susquehanna Portfolio Strategies, LLC $479,617 44,824 0.34% Shares
Mariner, LLC $416,218 38,895 0.29% Shares
D. E. Shaw & Co., Inc. $386,602 36,131 0.27% Shares
FMR LLC $378,010 35,328 0.27% Shares
PRELUDE CAPITAL MANAGEMENT, LLC $374,917 35,039 0.26% Shares
MARSHALL WACE, LLP $370,220 34,600 0.26% Shares
ALLIANCEBERNSTEIN L.P. $366,528 33,200 0.26% Shares
RHUMBLINE ADVISERS $350,471 32,755 0.25% Shares
BANK OF AMERICA CORP /DE/ $334,161 31,230 0.23% Shares
Squarepoint Ops LLC $333,883 31,204 0.23% Shares
MERCER GLOBAL ADVISORS INC /ADV $296,219 27,684 0.21% Shares
Quantinno Capital Management LP $288,590 26,971 0.20% Shares
Advantage Alpha Capital Partners LP $285,693 18,059 0.20% Shares
FEDERATED HERMES, INC. $268,153 25,061 0.19% Shares
CANADA PENSION PLAN INVESTMENT BOARD $247,170 23,100 0.17% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $225,160 21,043 0.16% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $210,524 17,841 0.15% Shares
MORGAN STANLEY $188,518 17,618 0.13% Shares
Creative Planning $178,776 16,708 0.13% Shares
MetLife Investment Management, LLC $178,497 16,682 0.13% Shares
Empowered Funds, LLC $177,984 16,634 0.13% Shares
WELLS FARGO & COMPANY/MN $165,636 15,480 0.12% Shares
Jump Financial, LLC $164,780 15,400 0.12% Shares
EJF Capital LP $160,500 15,000 0.11% Shares
EDBI Pte Ltd $159,962 10,105 0.11% Shares
CITADEL ADVISORS LLC $154,080 14,400 0.11% Put option
nVerses Capital, LLC $140,426 13,124 0.10% Shares
Cerity Partners LLC $136,308 12,739 0.10% Shares
Engineers Gate Manager LP $130,701 12,215 0.09% Shares
PDT Partners, LLC $122,034 11,405 0.09% Shares
Point72 Asset Management, L.P. $111,205 10,393 0.08% Shares
AMERICAN FINANCIAL GROUP INC $108,124 10,105 0.08% Shares
Arax Advisory Partners $107,503 10,047 0.08% Shares
NEW YORK STATE COMMON RETIREMENT FUND $97,541 9,116 0.07% Shares
CWM, LLC $95,143 8,618 0.07% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $91,068 8,511 0.06% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $85,311 7,973 0.06% Shares
CITIGROUP INC $85,044 7,948 0.06% Shares
Vanguard Global Advisers, LLC $85,012 7,945 0.06% Shares
Police & Firemen's Retirement System of New Jersey $82,390 7,700 0.06% Shares
Invesco Ltd. $81,170 7,586 0.06% Shares
JPMORGAN CHASE & CO $75,865 6,941 0.05% Shares
NISA INVESTMENT ADVISORS, LLC $42,682 3,989 0.03% Shares
China Universal Asset Management Co., Ltd. $33,705 3,150 0.02% Shares
IFP Advisors, Inc $32,239 3,013 0.02% Shares
NORTHERN TRUST CORP $30,977 2,895 0.02% Shares
Ameritas Investment Partners, Inc. $25,380 2,372 0.02% Shares
OSAIC HOLDINGS, INC. $21,421 2,002 0.02% Shares
Tower Research Capital LLC (TRC) $21,036 1,966 0.01% Shares
Legal & General Group Plc $20,747 1,939 0.01% Shares
AQR CAPITAL MANAGEMENT LLC $19,795 1,850 0.01% Shares
Point72 Asia (Singapore) Pte. Ltd. $19,554 1,236 0.01% Shares

Company insiders 17 insiders · 6 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Jasbir Seehra Chief Executive Officer April 8, 2023 M 252,856 0 0 $0
Keith Regnante Chief Financial Officer Jan. 4, 2024 M 0 0 0 $0
Christopher Rovaldi Chief Operating Officer Feb. 16, 2023 A 0 0 0 $0
Simon Peter Cooper Chief Medical Officer Feb. 16, 2023 A 0 0 $0
Jennifer Lachey Chief Scientific Officer July 15, 2022 M 95,100 0 0 $0
Claudia Ordonez Chief Medical Officer June 11, 2021 M 0 0 0 $0
Jean Jacques Bienaime Director July 15, 2026 P 18,592 5 0 $65,500
Anne Prener Director July 1, 2026 A 13,786 0 0 $0
Charles W. Newton Director June 11, 2026 S 12,665 0 1 $-5,522
Julius Knowles Director June 4, 2026 S 10,958 0 1 $-28,166
Nima Farzan Director June 4, 2026 S 9,767 0 1 $-28,166
Alpna Seth Director June 4, 2026 S 9,767 0 1 $-28,140
Mary Ann Gray Director June 3, 2026 A 12,392 0 0 $0
GORDON CARL L Director Nov. 21, 2025 D 45,057 0 0 $0
Ran Nussbaum Director June 6, 2023 A 1,226,412 0 0 $0
Tomer Kariv Director June 6, 2023 A 1,226,412 0 0 $0
Alon Lazarus Director April 13, 2020 C 2,013,102 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 4 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Pontifax Management 4 GP (2015) Ltd., Pontifax (Israel) IV, L.P., Pontifax (Cayman) IV, L.P., Pontifax (China) IV, L.P., Pontifax Late Stage Fund L.P., Pontifax Late Stage GP Ltd. ×3 filings Oct. 16, 2025 0.00% Amendment SEC
ADAR1 Capital Management, LLC, ADAR1 Capital Management GP, LLC, Daniel Schneeberger ×6 filings Oct. 15, 2025 0.00% Amendment SEC
OrbiMed Advisors LLC, OrbiMed Capital GP VII LLC, OrbiMed Genesis GP LLC, OrbiMed Capital LLC ×4 filings Dec. 13, 2023 Initial filing SEC
Arkin Bio Ventures Limited Partnership, Arkin Bio Venture Partners Ltd., Moshe Arkin, Alon Lazarus ×3 filings Dec. 17, 2020 Initial filing Board campaign SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 37 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.38% 12,830 NS April 30, 2026 N-PORT
OASC · Unified Series Trust 0.20% 15,034 NS May 31, 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0.10% 23,576 NS May 31, 2026 N-PORT
IWC · iShares Trust 0.05% 63,474 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.04% 38,819 NS May 31, 2026 N-PORT
SMLF · iShares Trust 0.03% 104,137 SH Aug. 8, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… 0.02% 6,426 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 55,956 SH Aug. 8, 2026 Daily
VFVA · VANGUARD WELLINGTON FUND 0.02% 17,295 SH Aug. 8, 2026 Daily
SFGV · EA Series Trust 0.02% 16,659 NS May 29, 2026 N-PORT
BIB · ProShares Trust 0.02% 1,125 NS May 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.02% 1,074 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.01% 132,792 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.01% 172,816 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.01% 27,974 NS May 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 106,081 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.01% 16,122 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 12,811 NS April 30, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.01% 63,454 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.01% 1,375 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.01% 465,257 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 65,248 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.00% 1,075 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.00% 92,945 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 1,085 NS May 31, 2026 N-PORT
AVUV · AMERICAN CENTURY ETF TRUST 0.00% 83,474 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 1,190 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 27 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 20,827 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 7,079 SH Aug. 8, 2026 Daily
DFAT · Dimensional ETF Trust 0.00% 4,070 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 11,035 NS May 31, 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0.00% 1,224 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 220,854 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 595,316 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 980 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 49,290 SH Aug. 8, 2026 Daily