SION Sionna Therapeutics, Inc. - Common Stock
$42.39
Price · May 22, 2026
Fundamentals as of May 12, 2026
52W Range
$13–$48
83% of range
Analyst Rating
BUY
16 analysts
Price Target
$52
+22% upside
P/E (TTM)
-21.9
ROE
-23.4%
Net Profit Margin
—
SION Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$42.38
Market Cap
$1.84B
P/E (TTM)
-21.9
EPS (TTM)
$-1.88
Revenue (TTM)
—
Div Yield
—
ROE
-23.4%
Debt/Equity
—
52W Range
$13 – $48
SION Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
—
EPS
$-1.88
2024-12-31
→
2025-12-31
Free Cash Flow
$-67M
2025-12-31
→
2025-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
SION
Peer Median
P/E (TTM)
-21.9
56.5
P/B
6.0
6.0
Price / FCF
-27.6
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
SION
Peer Median
ROA
-29.4%
-30.9%
ROE
-23.4%
-35.9%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
SION
Peer Median
Current Ratio
20.6
8.0
Quick Ratio
5.0
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
SION
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
SION
Peer Median
SION Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
16 analysts
- Strong Buy 6 37.5%
- Buy 8 50.0%
- Hold 1 6.2%
- Sell 1 6.2%
- Strong Sell 0 0.0%
12-Month Price Target
10 analysts · 2026-05-26
Median
$54.00
Now
$42.38
Low
$23.00
High
$63.00
Median target
$54.00
+27.4%
Mean target
$51.60
+21.7%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.01%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.60 | $-0.52 | -0.08% |
| Dec. 31, 2025 | $-0.46 | $-0.55 | 0.09% |
| Sept. 30, 2025 | $-0.46 | $-0.49 | 0.03% |
| June 30, 2025 | $-0.41 | $-0.57 | 0.16% |
| March 31, 2025 | $-0.62 | $-0.46 | -0.16% |
Peer Comparison Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| SION | $1.84B | -21.9 | — | — | -23.4% | — |
| BCRX | $1.66B | 6.4 | 94.1% | 30.2% | -97.6% | — |
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| ADMA | $4.34B | 30.4 | 19.6% | 28.8% | 33.6% | 57.4% |
| GENB | — | — | — | — | — | — |
| IOVA | $1.12B | -2.5 | 60.6% | -148.4% | -56.0% | — |
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| NRIX | $1.80B | -5.8 | 53.9% | -314.9% | -53.6% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 13
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| R&D Expense | $60M | $57M | |
| SG&A Expense | $29M | $13M | |
| Operating Expenses | $89M | $71M | |
| Operating Income | $-89M | $-71M | |
| Interest Income | $13M | $8M | |
| Other Non-op | $14M | $9M | |
| Income Tax | $0 | $0 | |
| Net Income | $-75M | $-62M | |
| EPS (Basic) | $-1.88 | $-15.99 | |
| EPS (Diluted) | $-1.88 | $-15.99 | |
| Shares (Basic) | 39,962,163 | 3,858,859 | |
| Shares (Diluted) | 39,962,163 | 3,858,859 | |
| EBITDA | $-89M | · |
Balance Sheet 19
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Cash & Equivalents | $58M | $38M | |
| Prepaid Expense | $6M | $3M | |
| Current Assets | $241M | $151M | |
| PP&E (Net) | $2M | $2M | |
| PP&E (Gross) | $4M | $4M | |
| Accum. Depreciation | $2M | $2M | |
| Other Non-current Assets | $0 | $3M | |
| Total Assets | $326M | $186M | |
| Accrued Liabilities | $10M | $8M | |
| Current Liabilities | $12M | $10M | |
| Capital Leases | $7M | $9M | |
| Total Liabilities | $19M | $19M | |
| Common Stock | $45.0K | $5.0K | |
| Paid-in Capital | $563M | $17M | |
| Retained Earnings | $-256M | $-181M | |
| AOCI | $540.0K | $368.0K | |
| Stockholders' Equity | $307M | $-164M | |
| Liabilities + Equity | $326M | $186M | |
| Shares Outstanding | 44,723,585 | 4,722,763 |
Cash Flow 7
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Stock-based Comp | $12M | $4M | |
| Operating Cash Flow | $-66M | $-53M | |
| CapEx | $377.0K | $27.0K | |
| Investing Cash Flow | $-119M | $-127M | |
| Financing Cash Flow | $206M | $179M | |
| Net Change in Cash | $21M | $-733.0K | |
| Free Cash Flow | $-67M | · |
Profitability 2
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| ROA | -29.4% | · | |
| ROE | -23.4% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Current Ratio | 20.6 | · | |
| Quick Ratio | 5.0 | · |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Net Income TTM | $-75M | $-62M | |
| Market Cap | $1.84B | · | |
| P/E | -21.9 | · | |
| P/B | 6.0 | · | |
| P / Tangible Book | 6.0 | · | |
| P / Cash Flow | -27.8 | · | |
| P / FCF | -27.6 | · | |
| Earnings Yield | -4.6% | · |
Income Statement 12
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $19M | $15M | $16M | $15M | $14M | $14M | |
| SG&A Expense | $11M | $8M | $8M | $7M | $6M | $4M | |
| Operating Expenses | $30M | $24M | $24M | $22M | $20M | $18M | |
| Operating Income | $-30M | $-24M | $-24M | $-22M | $-20M | $-18M | |
| Interest Income | $3M | $3M | $3M | $4M | $3M | $2M | |
| Other Non-op | $3M | $3M | $4M | $4M | $3M | $2M | |
| Net Income | $-27M | $-20M | $-20M | $-18M | $-16M | $-16M | |
| EPS (Basic) | $-0.60 | $1028.58 | $-0.46 | $-410.00 | $-0.62 | $6539.68 | |
| EPS (Diluted) | $-0.60 | $1028.58 | $-0.46 | $-410.00 | $-0.62 | $6539.68 | |
| Shares (Basic) | 44,921,984 | -75,005,946 | 44,255,053 | 44,116,997 | 26,596,059 | -6,869,404 | |
| Shares (Diluted) | 44,921,984 | -75,005,946 | 44,255,053 | 44,116,997 | 26,596,059 | -6,869,404 | |
| EBITDA | $-30M | · | $-24M | $-22M | $-20M | · |
Balance Sheet 19
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $63M | $58M | $51M | $41M | $83M | $38M | |
| Prepaid Expense | $5M | $6M | $4M | $4M | $4M | $3M | |
| Current Assets | $221M | $241M | $252M | $267M | $274M | $151M | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $2M | $2M | |
| PP&E (Gross) | $4M | $4M | $4M | $4M | $4M | $4M | |
| Accum. Depreciation | $2M | $2M | $2M | $2M | $2M | $2M | |
| Other Non-current Assets | $585.0K | $0 | $0 | $0 | $0 | $3M | |
| Total Assets | $305M | $326M | $339M | $352M | $370M | $186M | |
| Accrued Liabilities | $6M | $10M | $7M | $5M | $3M | $8M | |
| Current Liabilities | $10M | $12M | $10M | $8M | $10M | $10M | |
| Capital Leases | $7M | $7M | $8M | $8M | $8M | $9M | |
| Total Liabilities | $17M | $19M | $18M | $16M | $18M | $19M | |
| Common Stock | $45.0K | $45.0K | $44.0K | $44.0K | $44.0K | $5.0K | |
| Paid-in Capital | $571M | $563M | $557M | $552M | $549M | $17M | |
| Retained Earnings | $-283M | $-256M | $-236M | $-216M | $-198M | $-181M | |
| AOCI | $-84.0K | $540.0K | $420.0K | $183.0K | $301.0K | $368.0K | |
| Stockholders' Equity | $288M | $307M | $322M | $336M | $352M | $-164M | |
| Liabilities + Equity | $305M | $326M | $339M | $352M | $370M | $186M | |
| Shares Outstanding | 45,075,651 | 44,723,585 | 44,463,527 | 44,132,338 | 44,092,117 | 4,722,763 |
Cash Flow 7
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $4M | $3M | $3M | $2M | $1M | |
| Operating Cash Flow | $-22M | $-17M | $-15M | $-18M | $-16M | $-12M | |
| CapEx | $0 | $204.0K | $87.0K | $0 | $86.0K | $27.0K | |
| Investing Cash Flow | $25M | $23M | $23M | $-23M | $-141M | $15M | |
| Financing Cash Flow | $2M | $2M | $2M | $-312.0K | $202M | $-1M | |
| Net Change in Cash | $5M | $8M | $10M | $-42M | $45M | $2M | |
| Free Cash Flow | $-22M | · | · | · | $-16M | · |
Profitability 2
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| ROA | -7.9% | · | -11.9% | -10.3% | -8.9% | · | |
| ROE | -8.4% | · | -12.6% | -10.7% | -9.4% | · |
Liquidity & Solvency 2
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 22.6 | · | 25.6 | 35.3 | 28.7 | · | |
| Quick Ratio | 6.5 | · | 5.2 | 5.4 | 8.7 | · |
Valuation (TTM) 8
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-82M | · | $-80M | $-69M | $-62M | · | |
| Market Cap | $1.81B | · | $1.31B | $766M | $461M | · | |
| P/E | -0.1 | · | -0.0 | -0.0 | -0.0 | · | |
| P/B | 6.3 | · | 4.1 | 2.3 | 1.3 | · | |
| P / Tangible Book | 6.3 | · | 4.1 | 2.3 | 1.3 | · | |
| P / Cash Flow | -82.7 | · | · | · | -28.3 | · | |
| P / FCF | -82.7 | · | · | · | -28.2 | · | |
| Earnings Yield | -1026.9% | · | -3523.0% | -21588.9% | -68601.1% | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Net Income | $-75M | $-62M |
| Diluted EPS | $-1.88 | $-15.99 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Current Ratio | 20.6 | — |
| Quick Ratio | 5.0 | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Free Cash Flow | $-67M | — |
Latest News Recent headlines mentioning this company
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