LYEL — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| ARCH Venture Management, LLC | $45,525,211 | 3,247,162 | 18.97% | Shares |
| MWG Caph Ltd | $31,029,810 | 1,008,116 | 12.93% | Shares |
| VANGUARD GROUP INC | $25,437,516 | 826,430 | 10.60% | Shares |
| GSK plc | $21,252,859 | 1,512,659 | 8.86% | Shares |
| MWG Management Ltd. | $16,371,804 | 1,008,116 | 6.82% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $11,054,175 | 786,774 | 4.61% | Shares |
| Orland Properties Ltd | $10,603,507 | 754,698 | 4.42% | Shares |
| BlackRock, Inc. | $10,177,005 | 724,342 | 4.24% | Shares |
| Almitas Capital LLC | $8,168,768 | 581,407 | 3.40% | Shares |
| Foresite Capital Management V, LLC | $6,693,223 | 476,386 | 2.79% | Shares |
| MILLENNIUM MANAGEMENT LLC | $5,162,996 | 367,473 | 2.15% | Shares |
| Opaleye Management Inc. | $4,833,551 | 344,025 | 2.01% | Shares |
| venBio Partners LLC | $4,744,643 | 337,697 | 1.98% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $4,365,887 | 310,636 | 1.82% | Shares |
| Alphabet Inc. | $4,120,247 | 293,256 | 1.72% | Shares |
| STATE STREET CORP | $2,603,774 | 185,322 | 1.08% | Shares |
| HSG Holding Ltd | $2,139,801 | 152,299 | 0.89% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,829,169 | 130,190 | 0.76% | Shares |
| NORTHERN TRUST CORP | $1,664,925 | 118,500 | 0.69% | Shares |
| Qube Research & Technologies Ltd | $1,552,961 | 110,531 | 0.65% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,511,359 | 107,570 | 0.63% | Shares |
| MARSHALL WACE, LLP | $1,493,516 | 106,300 | 0.62% | Shares |
| Velan Capital Investment Management LP | $1,475,250 | 105,000 | 0.61% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,307,985 | 93,095 | 0.54% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1,291,069 | 91,891 | 0.54% | Shares |
| MIC Capital Management UK LLP | $1,222,743 | 87,028 | 0.51% | Shares |
| GOLDMAN SACHS GROUP INC | $1,219,245 | 86,779 | 0.51% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $957,066 | 68,315 | 0.40% | Shares |
| TWO SIGMA INVESTMENTS, LP | $743,624 | 52,927 | 0.31% | Shares |
| JANE STREET GROUP, LLC | $646,455 | 46,011 | 0.27% | Shares |
| Squarepoint Ops LLC | $594,624 | 42,322 | 0.25% | Shares |
| Ikarian Capital, LLC | $577,188 | 41,081 | 0.24% | Shares |
| MORGAN STANLEY | $520,553 | 37,050 | 0.22% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $413,225 | 29,411 | 0.17% | Shares |
| Point72 Asset Management, L.P. | $366,424 | 26,080 | 0.15% | Shares |
| UBS Group AG | $365,048 | 25,982 | 0.15% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $363,895 | 25,900 | 0.15% | Call option |
| Bank of New York Mellon Corp | $346,656 | 24,673 | 0.14% | Shares |
| AMERICAN CENTURY COMPANIES INC | $344,787 | 24,540 | 0.14% | Shares |
| Jump Financial, LLC | $308,482 | 21,956 | 0.13% | Shares |
| Clearstead Advisors, LLC | $280,410 | 19,958 | 0.12% | Shares |
| EntryPoint Capital, LLC | $272,710 | 19,410 | 0.11% | Shares |
| CITADEL ADVISORS LLC | $262,665 | 18,695 | 0.11% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $252,900 | 18,000 | 0.11% | Shares |
| CITADEL ADVISORS LLC | $251,495 | 17,900 | 0.10% | Put option |
| Susquehanna Portfolio Strategies, LLC | $251,144 | 17,875 | 0.10% | Shares |
| CITADEL ADVISORS LLC | $238,850 | 17,000 | 0.10% | Call option |
| Allspring Global Investments Holdings, LLC | $226,837 | 16,145 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $217,234 | 15,462 | 0.09% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $199,510 | 14,200 | 0.08% | Put option |
| Invesco Ltd. | $195,492 | 13,914 | 0.08% | Shares |
| Nuveen, LLC | $176,960 | 12,595 | 0.07% | Shares |
| Graham Capital Management, L.P. | $163,008 | 11,602 | 0.07% | Shares |
| Brevan Howard Capital Management LP | $162,376 | 11,557 | 0.07% | Shares |
| BANK OF AMERICA CORP /DE/ | $152,737 | 10,871 | 0.06% | Shares |
| Walleye Capital LLC | $146,837 | 10,451 | 0.06% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $133,545 | 9,505 | 0.06% | Shares |
| DEUTSCHE BANK AG\ | $129,091 | 9,188 | 0.05% | Shares |
| WELLS FARGO & COMPANY/MN | $112,470 | 8,005 | 0.05% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $110,222 | 7,845 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $72,568 | 5,165 | 0.03% | Shares |
| CITIGROUP INC | $70,601 | 5,025 | 0.03% | Shares |
| BARCLAYS PLC | $66,246 | 4,715 | 0.03% | Shares |
| JPMORGAN CHASE & CO | $61,149 | 4,796 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $60,879 | 4,333 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $57,605 | 4,100 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $52,182 | 3,714 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $48,416 | 3,446 | 0.02% | Shares |
| FMR LLC | $30,222 | 2,151 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $19,164 | 1,364 | 0.01% | Shares |
| Advisors Asset Management, Inc. | $17,452 | 567 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $14,668 | 1,044 | 0.01% | Shares |
| Legal & General Group Plc | $12,884 | 917 | 0.01% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $12,715 | 905 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $11,999 | 854 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $11,900 | 1,025 | 0.00% | Shares |
| Russell Investments Group, Ltd. | $10,565 | 752 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $10,000 | 742 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $6,351 | 452 | 0.00% | Shares |
| Truvestments Capital LLC | $4,215 | 300 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $3,175 | 226 | 0.00% | Shares |
| Sterling Capital Management LLC | $2,670 | 190 | 0.00% | Shares |
| Quarry LP | $2,515 | 179 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $1,236 | 88 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $955 | 68 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $836 | 59,748 | 0.00% | Shares |
| US BANCORP \DE\ | $815 | 58 | 0.00% | Shares |
| Cornerstone Financial Management LLC | $646 | 46 | 0.00% | Shares |
| HRT FINANCIAL LP | $513 | 36,575 | 0.00% | Shares |
| GAMMA Investing LLC | $492 | 35 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $431 | 30,657 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $368 | 26,225 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $351 | 25 | 0.00% | Shares |
| Optiver Holding B.V. | $281 | 20 | 0.00% | Shares |
| CWM, LLC | $40 | 2 | 0.00% | Shares |