Redmile Group, LLC
CIK 1425738 · View on SEC EDGAR ↗
- Portfolio value
- $1.5B
- Positions
- 39
- As of
- June 30, 2026
Portfolio value QoQ: -1.4% 13F does not disclose cash
- Top 10 holdings weight
- 73.48%
- Top 25 holdings weight
- 94.67%
- Positions above 1%
- 22
- Effective number of positions
- 12.7
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q2 2026: 6.68% Est. buys $100,160,800 · sells $445,586,574
Median holding: 4.0 quarters Tracked Q4 2024–Q2 2026 · 50.6% still held
- New positions
- 4
- Increased
- 5
- Decreased
- 23
- Closed
- 4
On this page
- Performance vs S&P How this manager's 13F portfolio performed against the S&P 500.
- Sector breakdown How the portfolio splits across market sectors.
- Portfolio Every stock this institution reports holding, from its latest 13F.
- Biggest new bets Brand-new positions opened in the latest quarter.
- Top moves The biggest position increases and decreases this quarter.
- Exited positions Positions the manager fully sold out of last quarter.
- Related The person behind this filer, where we can match one.
Performance vs S&P 500
Annualized: +44.2% · S&P 500: +18.0%
Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.
Priceable coverage: 97.9% · Options excluded: 0.0%
Sector breakdown
Full portfolio 39 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| SRRK Scholar Rock Holding Corporation - Common Stock | $237,110,060 | 15.92% | 4,311,092 | $-208,605,028 | Down ×1 | ||
| KRYS Krystal Biotech, Inc. - Common Stock | $234,897,298 | 15.77% | 632,005 | $60,917,486 | Down ×2 | ||
| STOK Stoke Therapeutics, Inc. - Common Stock | $129,110,502 | 8.67% | 3,945,920 | $-6,473,245 | Down ×1 | ||
| IMNM Immunome, Inc. - Common Stock | $104,076,592 | 6.99% | 4,911,590 | $-17,496,223 | Down ×2 | ||
| NRIX Nurix Therapeutics, Inc. - Common stock | $98,830,073 | 6.64% | 4,073,787 | $-21,028,451 | Down ×2 | ||
| ABSI Absci Corporation - Common Stock | $78,112,833 | 5.24% | 6,739,675 | $53,352,885 | Down ×1 | ||
| ANNX Annexon, Inc. - common stock | $67,776,998 | 4.55% | 11,869,877 | $-12,828,717 | Down ×1 | ||
| RGNX REGENXBIO Inc. - Common Stock | $52,338,272 | 3.51% | 4,368,804 | $15,727,694 | |||
| STTK Shattuck Labs, Inc. - Common Stock | $47,830,709 | 3.21% | 6,892,033 | $12,210,284 | Up ×1 | ||
| NGNE Neurogene Inc. - Common Stock | $44,413,659 | 2.98% | 1,412,199 | $14,988,143 | Down ×1 | ||
| BEAM Beam Therapeutics Inc. - Common Stock | $39,957,369 | 2.68% | 1,164,259 | $10,463,955 | Down ×5 | ||
| AGMB AgomAb Therapeutics NV - ADRs representing one common share. | $35,486,359 | 2.38% | 2,733,926 | $33,847,296 | Up ×1 | ||
| FATE Fate Therapeutics, Inc. - Common Stock | $34,756,954 | 2.33% | 12,872,946 | $19,309,419 | |||
| IDYA IDEAYA Biosciences, Inc. - Common Stock | $23,860,329 | 1.60% | 640,202 | $6,496,711 | Up ×1 | ||
| SLN Silence Therapeutics Plc - American Depository Share | $23,769,251 | 1.60% | 2,164,777 | $12,360,876 | |||
| COGT Cogent Biosciences, Inc. - Common Stock | $19,478,523 | 1.31% | 503,321 | $-7,003,983 | Down ×3 | ||
| SLDB Solid Biosciences Inc. - Common Stock | $19,467,463 | 1.31% | 1,948,695 | $4,981,819 | Down ×1 | ||
| NUVB Nuvation Bio Inc. Class A Common Stock | $17,216,131 | 1.16% | 3,031,009 | $3,688,663 | Down ×2 | ||
| CLDX Celldex Therapeutics, Inc. - Common Stock | $16,146,200 | 1.08% | 433,921 | $7,851,166 | Up ×1 | ||
| CLYM Climb Bio, Inc. - Common Stock | $15,991,343 | 1.07% | 1,226,330 | Up ×1 | |||
| ALXO ALX Oncology Holdings Inc. - Common Stock | $15,302,483 | 1.03% | 7,392,504 | $-665,714 | Down ×1 | ||
| BMRN BioMarin Pharmaceutical Inc. - Common Stock | $15,172,970 | 1.02% | 265,169 | $5,351,675 | Up ×1 | ||
| XENE Xenon Pharmaceuticals Inc. - Common Shares | $13,845,015 | 0.93% | 229,374 | $-1,429,478 | Down ×1 | ||
| ZYME Zymeworks Inc. - Common Stock | $12,851,836 | 0.86% | 491,654 | $540,820 | |||
| ADCT ADC Therapeutics SA Common Shares | $12,333,580 | 0.83% | 11,526,710 | $-45,680,803 | Down ×2 | ||
| AURA Aura Biosciences, Inc. - Common Stock | $11,833,336 | 0.79% | 1,666,667 | Up ×1 | |||
| Unknown issuer (CUSIP: 67613T104) | $7,951,750 | 0.53% | 425,000 | Up ×1 | |||
| LIVN LivaNova PLC - Ordinary Shares | $7,660,053 | 0.51% | 93,154 | $773,073 | Down ×6 | ||
| ESTA Establishment Labs Holdings Inc. - Common Shares | $7,634,001 | 0.51% | 88,964 | $1,759,315 | Down ×5 | ||
| CBLL CeriBell, Inc. - Common Stock | $7,522,988 | 0.51% | 386,786 | $433,201 | |||
| DBVT DBV Technologies S.A. - American Depositary Shares | $6,731,216 | 0.45% | 410,440 | $-3,532,877 | Down ×2 | ||
| INSM Insmed Incorporated - Common Stock | $5,462,569 | 0.37% | 51,234 | Up ×1 | |||
| PRME Prime Medicine, Inc. - Common Stock | $5,127,742 | 0.34% | 1,389,632 | $-408,353 | Down ×1 | ||
| ATRA Atara Biotherapeutics, Inc. - Common Stock | $5,070,727 | 0.34% | 441,701 | $2,981,481 | |||
| EPRX Eupraxia Pharmaceuticals Inc. - Common Stock | $4,041,354 | 0.27% | 611,400 | $-1,026,646 | Down ×1 | ||
| ORIC Oric Pharmaceuticals, Inc. - Common Stock | $3,920,568 | 0.26% | 362,010 | $-1,346,478 | Down ×2 | ||
| ARDX Ardelyx, Inc. - Common Stock | $3,272,925 | 0.22% | 641,750 | $-1,119,842 | Down ×1 | ||
| IVVD Invivyd, Inc. - Common Stock | $2,266,285 | 0.15% | 2,597,759 | $-1,176,972 | Down ×2 | ||
| PLRX Pliant Therapeutics, Inc. - Common Stock | $880,224 | 0.06% | 772,126 | $-92,655 | |||
| No matches | |||||||
Biggest new bets
New positions opened this quarter, largest first.
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| SRRK | Trimmed | -4.8M | -$208.6M |
| KRYS | Trimmed | -42K | +$60.9M |
| ABSI | Trimmed | -1.5M | +$53.4M |
| ADCT | Trimmed | -3.9M | -$45.7M |
| NRIX | Trimmed | -3.7M | -$21.0M |
| FATE | Price move only | +0 | +$19.3M |
| IMNM | Trimmed | -647K | -$17.5M |
| RGNX | Price move only | +0 | +$15.7M |
| NGNE | Trimmed | -47K | +$15.0M |
| ANNX | Trimmed | -2.7M | -$12.8M |
1 position hidden (data completeness check)
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| AKRO | Dec. 31, 2025 | 747,818 | $35,506,399 | No longer tracked |
| KYMR | Sept. 30, 2025 | 803,289 | $35,055,532 | 119.7% |
| RAPT | March 31, 2026 | 885,927 | $30,006,347 | No longer tracked |
| ETNB | Dec. 31, 2025 | 1,473,136 | $21,655,099 | No longer tracked |
| HNGE | Sept. 30, 2025 | 300,000 | $15,525,000 | 80.6% |
| SYK | March 31, 2025 | 30,676 | $11,044,894 | -8.7% |
| REPL | March 31, 2026 | 1,099,756 | $10,689,628 | 86.3% |
| BHVN | Sept. 30, 2025 | 729,515 | $10,293,457 | -7.4% |
| BSX | Sept. 30, 2025 | 85,301 | $9,162,180 | -47.3% |
| ISRG | March 31, 2025 | 16,943 | $8,843,568 | -20.3% |
| KROS | Dec. 31, 2025 | 552,506 | $8,740,645 | -47.1% |
| IMVT | June 30, 2025 | 490,394 | $8,380,833 | 176.7% |
| VERV | Sept. 30, 2025 | 740,261 | $8,313,131 | No longer tracked |
| ARDX | March 31, 2025 | 1,576,259 | $7,991,633 | -18.0% |
| PODD | June 30, 2025 | 27,109 | $7,119,094 | -51.7% |
| BNTX | June 30, 2025 | 73,071 | $6,653,845 | 1.9% |
| FOLD | Dec. 31, 2025 | 777,178 | $6,124,163 | No longer tracked |
| IRTC | June 30, 2025 | 56,844 | $5,950,430 | -18.0% |
| PEN | Sept. 30, 2025 | 18,818 | $4,829,263 | 29.0% |
| MASI | June 30, 2025 | 26,062 | $4,341,929 | No longer tracked |
| RPTX | March 31, 2026 | 1,586,174 | $4,124,052 | No longer tracked |
| STXS | March 31, 2025 | 1,799,465 | $4,102,780 | No longer tracked |
| ORKA | June 30, 2025 | 386,963 | $3,970,240 | 854.5% |
| XERS | Dec. 31, 2025 | 451,099 | $3,671,946 | 13.8% |
| VTYX | Dec. 31, 2025 | 1,073,386 | $3,338,230 | No longer tracked |
| IGMS | Sept. 30, 2025 | 2,952,131 | $3,306,387 | No longer tracked |
| CYTK | June 30, 2025 | 82,098 | $3,299,519 | 131.7% |
| LVTX | Dec. 31, 2025 | 2,074,372 | $3,236,020 | No longer tracked |
| ACIU | March 31, 2025 | 1,034,299 | $2,792,607 | 35.2% |
| ACHL | March 31, 2025 | 1,608,089 | $1,833,221 | No longer tracked |
| ATXS | June 30, 2025 | 269,078 | $1,436,877 | No longer tracked |
| ALVR | March 31, 2025 | 1,907,969 | $801,347 | No longer tracked |
| KLRS | March 31, 2026 | 82,955 | $700,140 | -27.2% |
| PRME | Dec. 31, 2025 | 87,118 | $482,634 | -2.0% |
| FDMT | Sept. 30, 2025 | 112,168 | $416,143 | 80.7% |
| ADAPY | March 31, 2025 | 715,607 | $385,497 | No longer tracked |
| BOLD | Dec. 31, 2025 | 245,458 | $301,913 | 140.8% |
| HOOK | March 31, 2025 | 106,376 | $213,816 | No longer tracked |
| ALLK | June 30, 2025 | 856,615 | $194,966 | No longer tracked |