AVXL Anavex Life Sciences Corp. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 28, 2026
$1.82
· of 52w range
· above low
· to high
$1.7252w low
$10.3852w high
Market Cap (MRQ)
$169M
P/E
-16.5
EPS
$-0.54
your badges
52W Range
$2–$10
Analyst Rating
BUY
Price Target
$20
P/E
-16.5
ROE
·
Net Profit Margin
-991.4%
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AVXL Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$1.82
Market Cap (MRQ)
$169M
P/E
-16.5
EPS
$-0.54
52W Range
$2–$10
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| Oct. 7, 2015 | 1-for-4 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
EPS$-0.542016-09-30 → 2025-09-30
Net margin-991.4%2016-09-30 → 2025-09-30
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | AVXL | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -16.55Y avg ≈-17.6 | ≈-17.6 | · | · | |
| P/B (MRQ) | 1.55Y avg ≈5.6 | ≈5.6 | 2.1 | Fair value | |
| Price / Tangible Book | 8.15Y avg ≈6.1 | ≈6.1 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | AVXL | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Operating Margin | -1098.9%5Y avg ≈-892.2% | ≈-892.2% | -734.7% | Top tier | |
| EBITDA Margin | -1098.9%5Y avg ≈-892.2% | ≈-892.2% | -734.7% | Top tier | |
| Pretax Margin | -991.4%5Y avg ≈-36410.5% | ≈-36410.5% | -688.6% | Weak | |
| Net Profit Margin | -991.4%5Y avg ≈-36665.2% | ≈-36665.2% | -692.5% | Top tier |
Financial Health Debt, liquidity, solvency — balance sheet strength
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | AVXL | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | -36.1%5Y avg ≈804.3% | ≈804.3% | · | · | |
| Revenue CAGR 3Y | 70.3%5Y avg ≈285.5% | ≈285.5% | · | · | |
| Revenue CAGR 5Y | 91.8% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
14.3%
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| Sept. 30, 2026 | Aug 25, 2026 | $-0.08 | $-0.08 | 2.0% |
| June 30, 2026 | Aug 10, 2026 | $-0.08 | $-0.08 | 2.0% |
| March 31, 2026 | $-0.06 | $-0.07 | 16.0% | |
| Dec. 31, 2025 | $-0.06 | $-0.11 | 46.5% | |
| Sept. 30, 2025 | $-0.11 | $-0.15 | 28.1% | |
| June 30, 2025 | $-0.16 | $-0.15 | -9.4% | |
| March 31, 2025 | $-0.13 | $-0.15 | 15.0% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $38M | $42M | $44M | $38M | $33M | $25M | $22M | $13M | $11M | $7M | $2M | $732.4K | |
| SG&A Expense | $14M | $11M | $12M | $13M | $9M | $6M | $7M | $6M | $5M | $8M | $5M | $2M | |
| Operating Expenses | $51M | $53M | $56M | $51M | $42M | $-31M | $29M | $19M | $16M | $16M | $7M | $3M | |
| Operating Income | $-51M | $-53M | $-56M | $-51M | $-42M | $-31M | · | · | · | · | · | $-3M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | · | $71.8K | $7.1K | |
| Other Non-op | $5M | $10M | $8M | $3M | $4M | $5M | $3M | $2M | $2M | $882.0K | $-5M | $-8M | |
| Pretax Income | $-46M | $-43M | $-47M | $-48M | $-38M | $-26M | $-26M | $-17M | $-13M | $-15M | $-12M | $-11M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | $-1M | |
| Net Income | $-46M | $-43M | $-48M | $-48M | $-38M | $-26M | $-26M | $-17M | $-13M | $-15M | $-12M | $-10M | |
| EPS (Basic) | $-0.54 | $-0.52 | $-0.60 | $-0.62 | $-0.54 | · | · | · | · | $-0.42 | $-0.65 | $-1.02 | |
| EPS (Diluted) | $-0.54 | $-0.52 | $-0.60 | $-0.62 | $-0.54 | · | · | · | · | $-0.42 | $-0.65 | $-1.02 | |
| Shares (Basic) | 85,289,447 | 83,468,049 | 79,787,596 | 76,909,993 | 69,802,960 | · | · | · | · | 35,153,426 | 18,584,820 | 9,804,539 | |
| Shares (Diluted) | 85,289,447 | 83,468,049 | 79,787,596 | 76,909,993 | 69,802,960 | · | · | · | · | 35,153,426 | 18,584,820 | 9,804,539 | |
| EBITDA | $-51M | $-53M | $-56M | · | · | · | · | · | · | $1.3K | $995 | $-3M |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $103M | $132M | $151M | $149M | $152M | $29M | $22M | $23M | $27M | $9M | $15M | $7M | |
| Prepaid Expense | $429.0K | $931.0K | $653.0K | $354.0K | $371.9K | $443.8K | $501.0K | $1M | $335.9K | $180.1K | $100.8K | $89.1K | |
| Current Assets | · | · | · | · | · | · | $25M | $26M | $28M | $9M | $15M | $7M | |
| PP&E (Net) | · | · | · | · | · | · | · | · | · | · | $1.3K | $2.2K | |
| Total Assets | $104M | $136M | $154M | $153M | $162M | $35M | $25M | $26M | $28M | $9M | $15M | $7M | |
| Accounts Payable | $4M | $10M | $4M | $4M | $5M | $4M | $4M | $3M | $4M | $3M | $3M | $1M | |
| Accrued Liabilities | $4M | $5M | $7M | $6M | $6M | $3M | $2M | $929.3K | · | · | · | · | |
| Short-term Debt | · | · | · | · | · | · | · | · | · | · | $85.2K | $192.1K | |
| Current Liabilities | · | · | · | · | $11M | $7M | $5M | $4M | $4M | $3M | $3M | $1M | |
| Total Liabilities | $9M | $15M | $13M | $10M | $11M | $7M | $5M | · | $4M | $3M | $3M | $7M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | $332 | $6M | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | $85.6K | $192.1K | |
| Common Stock | $87.0K | $85.0K | $82.0K | $78.0K | $75.9K | $62.0K | $52.7K | $45.9K | $43.3K | $36.2K | $32.0K | $11.8K | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | · | · | $52M | |
| Retained Earnings | $-382M | $-336M | $-293M | $-246M | $-198M | $-160M | $-133M | $-107M | $-91M | $-78M | $-63M | $-51M | |
| Stockholders' Equity | $95M | $120M | $142M | $142M | $151M | $27M | $20M | $22M | $26M | $6M | $13M | $192.6K | |
| Liabilities + Equity | $104M | $136M | $154M | $153M | $162M | $35M | $25M | $26M | $28M | $9M | $15M | $7M | |
| Shares Outstanding | 86,668,521 | 84,795,517 | 82,066,511 | 77,942,815 | 75,918,465 | 62,045,198 | 52,650,521 | 45,933,472 | 43,330,817 | 36,168,299 | 32,044,213 | 11,800,063 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | · | $1.3K | $995 | $768 | |
| Stock-based Comp | $12M | $9M | $16M | $18M | $8M | $5M | $6M | $6M | $4M | $5M | $2M | $637.9K | |
| Deferred Tax | · | · | $7.0K | $358.0K | $268.0K | $22.7K | $82.2K | $72.7K | · | · | · | $-1M | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | $436.4K | $6M | · | |
| Operating Cash Flow | $-39M | $-31M | $-28M | $-24M | $-30M | $-21M | $-19M | $-13M | $-9M | $-9M | $-4M | $-3M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | · | $3.0K | |
| Investing Cash Flow | · | · | · | · | · | · | · | · | · | · | · | $-3.0K | |
| Stock Issued | · | $11M | $28M | $21M | $153M | $29M | $18M | $8M | $27M | $3M | $12M | $368.2K | |
| Net Stock Activity | · | $11M | $28M | · | $153M | $29M | $18M | $8M | $27M | · | · | $368.2K | |
| Financing Cash Flow | $9M | $12M | $30M | $21M | $153M | $28M | $18M | $8M | $27M | $3M | $12M | $10M | |
| Net Change in Cash | · | · | · | · | · | $7M | $-745.0K | · | · | · | · | $7M |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1098.9% | -722.4% | -855.3% | · | · | · | · | · | · | · | · | · | |
| Net Margin | -991.4% | -587.5% | -728.7% | · | -144353.4% | -14602.4% | -12685.7% | -6842.0% | -15278.9% | -130159.9% | · | · | |
| Pretax Margin | -991.4% | -587.5% | -728.6% | · | -143334.5% | -14589.9% | -12646.1% | -6813.5% | -15211.2% | -129898.3% | · | · | |
| EBITDA Margin | -1098.9% | -722.4% | -855.3% | · | · | · | · | · | · | 11.1% | · | · | |
| ROA | · | -29.7% | -30.9% | · | -38.6% | -87.8% | -102.0% | -66.8% | -72.1% | -118.0% | -106.1% | -293.5% | |
| ROE | · | -34.4% | -32.9% | · | -24.6% | -101.2% | -126.8% | -79.2% | -88.1% | -154.2% | -186.3% | 1001.4% |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | · | · | · | · | · | 5.0 | 6.3 | · | 3.0 | 5.8 | 5.1 | |
| Quick Ratio | · | · | · | · | · | · | 4.4 | 5.9 | · | 2.9 | 5.7 | 5.0 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | 0.0 | 1.0 | |
| LT Debt / Equity | · | · | · | · | · | · | · | · | · | · | 0.0 | · | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | · | · | -418.8 |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | 0.1 | 0.0 | · | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | · | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | · | $1.42 | $1.73 | · | $1.99 | $0.44 | $0.39 | $0.45 | $0.56 | $0.17 | $0.40 | $0.00 | |
| Revenue / Share | $0.05 | $0.09 | $0.08 | · | · | · | · | · | · | $0.00 | · | · | |
| Cash Flow / Share | $-0.46 | $-0.37 | $-0.35 | · | · | · | · | · | · | $-0.26 | $-0.23 | $-0.07 | |
| Cash / Share | · | $1.56 | $1.84 | · | $2.00 | $0.47 | $0.42 | $0.50 | $0.63 | $0.25 | $0.48 | $0.15 | |
| EPS (TTM) | $-0.54 | $-0.52 | $-0.60 | $-0.62 | $-0.54 | $-0.24 | $-0.24 | $-0.24 | $-0.24 | $-0.42 | $-0.65 | $-1.02 |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -36.1% | 12.3% | 588.4% | 3542.3% | -85.5% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | 70.3% | 555.4% | 230.9% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 91.8% | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $5M | $7M | $7M | $947.0K | $26.0K | $180.0K | $207.3K | $255.1K | $88.1K | $11.3K | $-71.8K | $-7.1K | |
| Net Income TTM | $-46M | $-43M | $-48M | $-48M | $-38M | $-26M | $-26M | $-17M | $-13M | $-15M | $-12M | $-10M | |
| Market Cap | · | $482M | $538M | · | $1.36B | $282M | $166M | $125M | $179M | $131M | $181M | $35M | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | $166M | $28M | |
| P/E | -16.5 | -10.9 | -10.9 | -16.6 | -33.2 | -19.0 | -13.2 | -11.4 | -17.2 | -8.6 | -8.7 | -0.7 | |
| P/S | · | 65.8 | 82.5 | · | 52412.9 | 1568.6 | 802.7 | 491.6 | 2036.3 | 11596.1 | -2516.2 | -4900.5 | |
| P/B | · | 4.0 | 3.8 | · | 9.0 | 10.4 | 8.2 | 6.1 | 7.4 | 20.8 | 14.1 | 180.3 | |
| P / Tangible Book | 8.1 | 4.0 | 3.8 | 5.6 | 9.0 | 10.4 | · | · | · | · | · | · | |
| P / Cash Flow | · | -15.6 | -19.3 | · | -44.9 | -13.3 | -9.0 | -10.0 | -19.9 | -14.2 | -42.8 | -13.1 | |
| EV / EBITDA | · | · | · | · | · | · | · | · | · | · | 166355.7 | -9.3 | |
| EV / Revenue | · | · | · | · | · | · | · | · | · | · | -2304.5 | -3903.1 | |
| Earnings Yield | -6.1% | -9.2% | -9.2% | -6.0% | -3.0% | -5.3% | -7.6% | -8.8% | -5.8% | -11.6% | -11.5% | -138.6% |
Income Statement
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | · | $4M | $5M | $7M | $10M | $10M | $10M | $12M | $12M | $10M | $9M | $10M | $10M | $11M | $12M | $11M | |
| SG&A Expense | $2M | $2M | $2M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $4M | |
| Operating Expenses | $-7M | $6M | $7M | $11M | $14M | $13M | $14M | $14M | $15M | $13M | $11M | $13M | $14M | $14M | $15M | $15M | |
| Operating Income | $7M | $-6M | $-7M | $-11M | $-14M | $-13M | $-14M | $-14M | $-15M | $-13M | $-11M | $-13M | $-14M | $-14M | $-15M | $-15M | |
| Other Non-op | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $3M | $2M | $2M | $3M | $2M | $2M | $1M | $2M | $1M | |
| Pretax Income | · | · | · | · | · | · | · | $-12M | $-12M | $-10M | $-9M | $-10M | $-11M | $-13M | $-13M | $-14M | |
| Income Tax | · | · | $18.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Net Income | $8M | $-5M | $-6M | $-10M | $-13M | $-11M | $-12M | $-12M | $-12M | $-11M | $-9M | $-10M | $-11M | $-13M | $-13M | $-14M | |
| EPS (Basic) | $0.08 | $-0.06 | $-0.06 | $-0.11 | $-0.16 | $-0.13 | $-0.14 | $-0.14 | $-0.14 | $-0.13 | $-0.11 | $-0.12 | $-0.14 | $-0.17 | $-0.17 | · | |
| EPS (Diluted) | $0.08 | $-0.06 | $-0.06 | $-0.11 | $-0.16 | $-0.13 | $-0.14 | $-0.14 | $-0.14 | $-0.13 | $-0.11 | $-0.12 | $-0.14 | $-0.17 | $-0.17 | · | |
| Shares (Basic) | 92,696,842,000 | 92,675,753 | 89,029,458 | · | 85,380,587,000 | 85,073,769 | 84,805,974 | · | 84,535,328 | 82,464,226 | 82,077,815 | · | 80,875,235 | 78,304,363 | 77,977,112 | · | |
| Shares (Diluted) | 92,899,536,000 | 92,675,753 | 89,029,458 | · | 85,380,587,000 | 85,073,769 | 84,805,974 | · | 84,535,328 | 82,464,226 | 82,077,815 | · | 80,875,235 | 78,304,363 | 77,977,112 | · | |
| EBITDA | $7M | $-6M | · | · | $-14M | $-13M | $-14M | · | $-15M | $-13M | $-11M | · | $-14M | $-14M | $-15M | · |
Balance Sheet
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $118M | $127M | $132M | $103M | $101M | $116M | $121M | $132M | $139M | $139M | $144M | · | $155M | $153M | $144M | $149M | |
| Prepaid Expense | $818.0K | $412.0K | $396.0K | $429.0K | $448.0K | $702.0K | $711.0K | $931.0K | $1M | $1M | $756.0K | · | $827.6K | $981.8K | $655.6K | $354.0K | |
| Total Assets | $120M | $129M | $133M | $104M | $102M | $117M | $124M | $136M | $142M | $145M | $148M | · | $158M | $159M | $148M | $153M | |
| Accounts Payable | $4M | $3M | $3M | $4M | $7M | $7M | $5M | $10M | $4M | $4M | $4M | · | $4M | $6M | $5M | $4M | |
| Accrued Liabilities | $4M | $4M | $3M | $4M | $4M | $10M | $8M | $5M | $7M | $5M | $7M | · | $6M | $7M | $7M | $6M | |
| Total Liabilities | $8M | $7M | $6M | $9M | $11M | $17M | $13M | $15M | $12M | $10M | $12M | · | $11M | $14M | $13M | $10M | |
| Common Stock | $93.0K | $93.0K | $93.0K | $87.0K | $85.0K | $85.0K | $85.0K | $85.0K | $85.0K | $84.0K | $82.0K | · | $81.4K | $80.2K | $78.0K | $78.0K | |
| Retained Earnings | $-386M | $-393M | $-388M | $-382M | $-373M | $-359M | $-348M | $-336M | $-324M | $-312M | $-302M | · | $-283M | $-272M | $-259M | $-246M | |
| Stockholders' Equity | $112M | $122M | $127M | $95M | $91M | $100M | $111M | $120M | $130M | $135M | $136M | $142M | $147M | $145M | $135M | $142M | |
| Liabilities + Equity | $120M | $129M | $133M | $104M | $102M | $117M | $124M | $136M | $142M | $145M | $148M | · | $158M | $159M | $148M | $153M | |
| Shares Outstanding | 92,696,842 | 92,696,842 | 92,671,758 | 86,668,521 | 85,411,692 | 85,333,652 | 84,985,449 | 84,795,517 | 84,795,517 | 83,616,218 | 82,086,511 | · | 81,390,916 | 80,235,398 | 78,032,135 | 77,942,815 |
Cash Flow
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $-17M | $314.0K | $1M | $4M | $4M | $1M | $2M | $2M | $2M | $3M | $2M | $3M | $4M | $4M | $5M | $6M | |
| Operating Cash Flow | $-9M | $-4M | $-7M | $-9M | $-12M | $-6M | $-12M | $-7M | $-5M | $-12M | $-7M | $-6M | $-8M | $-8M | $-6M | $-4M | |
| Stock Issued | · | · | · | · | · | · | · | · | $4M | · | · | · | $9M | · | · | $2.9K | |
| Financing Cash Flow | $0 | $113.0K | $36M | $10M | $-2M | $852.0K | $708.0K | $89.0K | $5M | $7M | $59.0K | $2M | $9M | $18M | $258.0K | $2.5K |
Profitability
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 628.5% | -611.1% | · | · | -1345.0% | -1034.1% | -975.0% | · | -820.1% | -712.9% | -562.4% | · | -740.2% | -968.4% | -1213.6% | · | |
| Net Margin | 729.9% | -503.1% | · | · | -1231.9% | -925.3% | -868.8% | · | -680.1% | -600.6% | -429.4% | · | -617.1% | -894.6% | -1023.3% | · | |
| Pretax Margin | · | · | · | · | · | · | · | · | -683.8% | -594.6% | -425.1% | · | -614.8% | -891.1% | -1024.9% | · | |
| EBITDA Margin | 628.5% | -611.1% | · | · | -1345.0% | -1034.1% | -975.0% | · | -820.1% | -712.9% | -562.4% | · | -740.2% | -968.4% | -1213.6% | · | |
| ROA | 7.0% | -4.3% | · | · | -10.9% | -8.6% | -8.9% | · | -8.2% | -6.9% | -5.8% | · | -7.1% | -8.2% | -8.5% | · | |
| ROE | 7.7% | -4.8% | · | · | -12.0% | -9.5% | -9.8% | · | -8.8% | -7.5% | -6.4% | · | -7.6% | -8.8% | -9.2% | · |
Efficiency
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · |
Per Share
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $1.21 | $1.31 | · | · | $1.06 | $1.17 | $1.31 | · | $1.53 | $1.61 | $1.65 | · | $1.80 | $1.81 | $1.73 | · | |
| Revenue / Share | $0.00 | $0.01 | · | · | $0.01 | $0.01 | $0.02 | · | $0.02 | $0.02 | $0.02 | · | · | · | · | · | |
| Cash Flow / Share | · | · | · | · | · | · | $-0.14 | · | · | · | $-0.09 | · | · | · | · | · | |
| Cash / Share | $1.28 | $1.37 | · | · | $1.18 | $1.36 | $1.42 | · | $1.64 | $1.67 | $1.75 | · | $1.90 | $1.91 | $1.84 | · | |
| EPS (TTM) | $-0.15 | $-0.39 | $-0.49 | · | $-0.57 | $-0.55 | $-0.55 | · | $-0.50 | $-0.50 | $-0.54 | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | Q3 2026 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $4M | $5M | · | $5M | $6M | $7M | · | $8M | $8M | $7M | · | $5M | $4M | $2M | · | |
| Net Income TTM | $-13M | $-34M | $-42M | · | $-48M | $-47M | $-46M | · | $-42M | $-41M | $-43M | · | $-52M | $-53M | $-50M | · | |
| Market Cap | $240M | $285M | · | · | $787M | $732M | $913M | · | $358M | $426M | $764M | · | $662M | $688M | $723M | · | |
| P/E | -17.3 | -7.9 | -7.3 | · | -16.2 | -15.6 | -19.5 | · | -8.4 | -10.2 | -17.2 | · | · | · | · | · | |
| P/S | 57.0 | 67.5 | · | · | 144.8 | 118.9 | 136.1 | · | 47.6 | 56.4 | 105.3 | · | 125.7 | 187.5 | 326.9 | · | |
| P/B | 2.1 | 2.3 | · | · | 8.7 | 7.3 | 8.2 | · | 2.8 | 3.2 | 5.6 | · | 4.5 | 4.7 | 5.3 | · | |
| P / Tangible Book | 2.1 | 2.3 | 2.6 | · | 8.7 | 7.3 | 8.2 | · | 2.8 | 3.2 | 5.6 | · | 4.5 | 4.7 | 5.3 | · | |
| P / Cash Flow | · | · | · | · | · | · | -75.3 | · | · | · | -104.4 | · | · | · | -124.7 | · | |
| Earnings Yield | -5.8% | -12.7% | -13.8% | · | -6.2% | -6.4% | -5.1% | · | -11.8% | -9.8% | -5.8% | · | · | · | · | · |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-09-30 | 2024-09-30 | 2023-09-30 | 2022-09-30 | 2021-09-30 |
|---|---|---|---|---|---|
| Operating Margin % | -1098.9% | -722.4% | -855.3% | · | · |
| Net Income | $-46M | $-43M | $-48M | $-48M | $-38M |
| Diluted EPS | $-0.54 | $-0.52 | $-0.60 | $-0.62 | $-0.54 |
No data for this statement
Not enough fundamentals data to build this statement yet.
No data for this statement
Not enough fundamentals data to build this statement yet.
Institutional owners (13F) 203 filers · $124.3M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
203
Value held
$124.3M
New positions
28
Exited positions
35
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 28 (-16 vs prior Q) | 35 (+5 vs prior Q) | 63 (-12 vs prior Q) | 61 (+11 vs prior Q) | -4.1M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| BlackRock, Inc. | $20,864,076 | 8,055,628 | 16.79% | Shares |
| VANGUARD GROUP INC | $17,901,581 | 5,028,534 | 14.40% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $10,501,386 | 4,054,589 | 8.45% | Shares |
| TWO SIGMA INVESTMENTS, LP | $7,890,533 | 3,046,538 | 6.35% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $6,236,854 | 2,407,473 | 5.02% | Shares |
| STATE STREET CORP | $4,979,974 | 1,922,770 | 4.01% | Shares |
| TWO SIGMA ADVISERS, LP | $4,306,069 | 1,209,570 | 3.46% | Shares |
| FEDERATED HERMES, INC. | $2,775,985 | 1,071,809 | 2.23% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $2,494,204 | 963,014 | 2.01% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2,456,959 | 948,633 | 1.98% | Shares |
| Summit Financial, LLC | $2,355,422 | 909,430 | 1.89% | Shares |
| GOLDMAN SACHS GROUP INC | $2,306,742 | 890,634 | 1.86% | Shares |
| MARSHALL WACE, LLP | $2,303,865 | 889,523 | 1.85% | Shares |
| NORTHERN TRUST CORP | $2,031,839 | 784,494 | 1.63% | Shares |
| BARCLAYS PLC | $1,953,447 | 754,226 | 1.57% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,903,119 | 734,795 | 1.53% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,694,624 | 654,295 | 1.36% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,609,558 | 621,451 | 1.29% | Shares |
| UBS Group AG | $1,606,769 | 620,374 | 1.29% | Shares |
| GREAT POINT PARTNERS LLC | $1,350,167 | 521,300 | 1.09% | Call option |
| WOLVERINE TRADING, LLC | $1,310,475 | 151,500 | 1.05% | Call option |
| Private Advisor Group, LLC | $1,305,360 | 504,000 | 1.05% | Shares |
| Sheets Smith Investment Management | $1,209,937 | 135,948 | 0.97% | Shares |
| LPL Financial LLC | $1,051,822 | 406,109 | 0.85% | Shares |
| STIFEL FINANCIAL CORP | $861,429 | 332,597 | 0.69% | Shares |
| CITADEL ADVISORS LLC | $852,408 | 329,115 | 0.69% | Shares |
| PVG ASSET MANAGEMENT CORP | $847,821 | 327,344 | 0.68% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $827,580 | 319,529 | 0.67% | Shares |
| Bank of New York Mellon Corp | $746,435 | 288,199 | 0.60% | Shares |
| WOLVERINE TRADING, LLC | $674,700 | 78,000 | 0.54% | Put option |
| Apella Capital, LLC | $617,866 | 227,995 | 0.50% | Shares |
| CITADEL ADVISORS LLC | $560,217 | 216,300 | 0.45% | Call option |
| CANADA PENSION PLAN INVESTMENT BOARD | $522,662 | 201,800 | 0.42% | Shares |
| MORGAN STANLEY | $504,955 | 194,963 | 0.41% | Shares |
| Nuveen, LLC | $473,249 | 182,722 | 0.38% | Shares |
| AllSquare Wealth Management LLC | $466,209 | 52,383 | 0.38% | Shares |
| ALLIANCEBERNSTEIN L.P. | $449,141 | 146,300 | 0.36% | Shares |
| Point72 Asset Management, L.P. | $407,889 | 157,486 | 0.33% | Shares |
| ENVESTNET ASSET MANAGEMENT INC | $378,995 | 146,330 | 0.30% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $355,348 | 137,200 | 0.29% | Put option |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $318,570 | 123,000 | 0.26% | Shares |
| WELLS FARGO & COMPANY/MN | $302,186 | 116,674 | 0.24% | Shares |
| D. E. Shaw & Co., Inc. | $299,047 | 115,462 | 0.24% | Shares |
| IEQ CAPITAL, LLC | $295,902 | 114,248 | 0.24% | Shares |
| RHUMBLINE ADVISERS | $290,194 | 112,049 | 0.23% | Shares |
| Invesco Ltd. | $284,765 | 109,948 | 0.23% | Shares |
| HSBC HOLDINGS PLC | $270,178 | 102,925 | 0.22% | Shares |
| CITADEL ADVISORS LLC | $263,403 | 101,700 | 0.21% | Put option |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $251,036 | 96,925 | 0.20% | Shares |
| ALPS ADVISORS INC | $243,592 | 94,051 | 0.20% | Shares |
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Athanasios Skarpelos ×4 filings | Nov. 20, 2009 | · | Initial filing | · | SEC |
| Athanansios Skarpelos | Oct. 31, 2007 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 19 insiders · 4 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Christopher U Missling | President and CEO | Jan. 6, 2026 A | 1,510,165 | 0 | 0 | $0 |
| Harvey Lalach | President COO Secretary | May 29, 2012 S | 550,000 | 0 | 0 | $0 |
| Sandra Boenisch | PFO & Treasurer | Sept. 24, 2026 A | 22,963 | 0 | 0 | $0 |
| George F Tidmarsh | Executive Director | Feb. 9, 2012 J | 8,000 | 0 | 0 | $0 |
| Steffen Thomas | Director | June 5, 2025 M | 43,651 | 0 | 0 | $0 |
| Jiong Ma | Director | March 31, 2025 A | · | 0 | 0 | $0 |
| Claus Vander Velden | Director | March 31, 2025 A | · | 0 | 0 | $0 |
| Peter D.O. Donhauser | Director | March 31, 2025 A | 5,000 | 0 | 0 | $0 |
| Athanasios Skarpelos | Director | March 31, 2025 A | 1,306,458 | 0 | 0 | $0 |
| Elliot Favus | Director | May 21, 2021 M | 0 | 0 | 0 | $0 |
| Bernd Metzner | Director | Sept. 22, 2016 A | · | 0 | 0 | $0 |
| David L. Tousley | Director | Sept. 1, 2010 A | · | 0 | 0 | $0 |
| Alison E. Ayers | Director | June 29, 2010 A | · | 0 | 0 | $0 |
| Cameron Durrant | Director | June 29, 2010 A | 0 | 0 | 0 | $0 |
| Angela Vernadaki | · | Feb. 8, 2007 P | · | 0 | 0 | $0 |
| George Kalkanis | · | Feb. 8, 2007 P | · | 0 | 0 | $0 |
| Panos Kontzalis | · | Feb. 8, 2007 P | · | 0 | 0 | $0 |
| Yang Wu | · | April 25, 2006 S | 0 | 0 | 0 | $0 |
| Pei Ru Wu | · | April 25, 2006 S | 0 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 19 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 0.25% | 7,124 SH | Sept. 11, 2026 | Daily |
| IWC · iShares Trust | 0.06% | 312,610 SH | Sept. 11, 2026 | Daily |
| IBB · iShares Trust | 0.02% | 673,391 SH | Sept. 11, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.01% | 6,545 SH | Oct. 2, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 529,519 SH | Aug. 19, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.01% | 66,934 SH | Aug. 19, 2026 | Daily |
| IWM · iShares Trust | 0.01% | 2,373,744 SH | Sept. 11, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.01% | 87,085 SH | Oct. 2, 2026 | Daily |
| IWO · iShares Trust | 0.00% | 142,968 SH | Sept. 11, 2026 | Daily |
| ITOT · iShares Trust | 0.00% | 124,161 SH | Sept. 11, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 19,807 SH | Sept. 3, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 1,041,514 SH | Aug. 19, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 2,925,439 SH | Aug. 19, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.00% | 17,218 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 6,160 SH | Aug. 19, 2026 | Daily |
| DFAC · Dimensional ETF Trust | 0.00% | 4,671 NS | July 31, 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0.00% | 267,123 SH | Aug. 19, 2026 | Daily |
| IWN · iShares Trust | · | 732,964 SH | Sept. 11, 2026 | Daily |
| SMLF · iShares Trust | · | 164,250 SH | Sept. 11, 2026 | Daily |
AVXL Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 7 analysts
BUY
Median target
$20.00
+998.9%
2 28.6%
Strong Buy
4 57.1%
Buy
1 14.3%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
1 analysts · 2026-09-28Mean target $20.00 +998.9%
Low$20.00
Mean$20.00
High$20.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| AVXL | · | -16.5 | -36.1% | -991.4% | · | · |
| PYXS | $72M | -0.9 | -14.2% | -574.5% | -112.9% | · |
| ORGO | $658M | 34.5 | 17.0% | 6.6% | 13.9% | · |
| ALXO | $61M | -0.6 | · | · | -225.0% | · |
| DTIL | $100M | -1.2 | -50.1% | -133.4% | -72.4% | · |
| CMPX | $958M | · | · | · | -45.9% | · |
| VYGR | $232M | -1.9 | -49.5% | -296.5% | -54.4% | · |
| TARA | $286M | -4.0 | · | · | -33.7% | · |
| TNXP | $200M | -1.1 | 29.8% | -946.2% | -60.0% | · |
| NERV | $174M | -0.1 | · | · | 339.5% | · |
| PEPG | $448M | -3.1 | · | · | -82.0% | · |
Latest News Recent headlines mentioning this company
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Source: SEC 10-K/A filed Aug 28, 2026