CMPX Compass Therapeutics, Inc. - Common Stock
$2.31
Price · Aug 18, 2026
Fundamentals as of Aug 6, 2026
52W Range
$2–$7
13% of range
Analyst Rating
BUY
21 analysts
Price Target
$9
+286% upside
P/E (TTM)
—
ROE
-45.9%
Net Profit Margin
—
CMPX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$2.31
Market Cap
$412M
P/E (TTM)
—
EPS (TTM)
—
Revenue (TTM)
$0
Div Yield
—
ROE
-45.9%
Debt/Equity
—
52W Range
$2 – $7
CMPX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$0
2023-12-31
→
2025-12-31
EPS
—
Free Cash Flow
$-49M
2020-12-31
→
2025-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
CMPX
Peer Median
P/B
2.1
4.8
Price / FCF
-8.4
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
CMPX
Peer Median
ROA
-36.9%
-41.1%
ROE
-45.9%
-52.6%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
CMPX
Peer Median
Current Ratio
15.0
7.7
Quick Ratio
15.0
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
CMPX
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
CMPX
Peer Median
CMPX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
21 analysts
- Strong Buy 9 42.9%
- Buy 10 47.6%
- Hold 2 9.5%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
12 analysts · 2026-08-13
Median
$7.00
Mean
$8.92
← Below all targets
$2.31
Low
$5.00
High
$24.00
Median target
$7.00
+203.0%
Mean target
$8.92
+286.0%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.00%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.13 | $-0.11 | -0.02% |
| March 31, 2026 | $-0.10 | $-0.10 | 0.00% |
| Dec. 31, 2025 | $-0.09 | $-0.09 | 0.00% |
| Sept. 30, 2025 | $-0.08 | $-0.14 | 0.06% |
| June 30, 2025 | $-0.14 | $-0.12 | -0.02% |
| March 31, 2025 | $-0.12 | $-0.11 | -0.01% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CMPX | $958M | — | — | — | -45.9% | — |
| PBYI | $300M | 9.8 | -0.91% | 13.6% | 26.5% | — |
| RZLT | $388M | -4.6 | — | — | -56.9% | — |
| BNTC | $307M | -11.1 | — | — | -43.8% | — |
| EDIT | $201M | -1.1 | 25.4% | -395.0% | -688.8% | — |
| PROK | — | — | 1075.0% | -7725.2% | 6.9% | — |
| FENC | $263M | -22.6 | -6.1% | -21.8% | -69.6% | — |
| LXEO | $725M | -5.3 | — | — | -51.9% | — |
| CAPR | $1.66B | -12.8 | -11.6% | — | -51.1% | — |
| FHTX | $306M | -4.6 | 36.8% | -240.3% | 80.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $0 | $850.0K | $0 | |
| R&D Expense | $56M | $42M | $38M | |
| SG&A Expense | $17M | $15M | $12M | |
| Operating Expenses | $73M | $57M | $50M | |
| Operating Income | $-73M | $-57M | $-50M | |
| Interest Income | $6M | $7M | $8M | |
| Other Non-op | $6M | $7M | $8M | |
| Pretax Income | · | · | $-42M | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-66M | $-49M | $-42M | |
| EPS (Basic) | $-0.42 | $-0.36 | $-0.33 | |
| Shares (Basic) | 157,695,000 | 137,384,000 | 127,027,000 | |
| Shares (Diluted) | · | 137,400,000 | · | |
| EBITDA | $-73M | $-57M | $-50M |
Balance Sheet 20
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $31M | $43M | $24M | |
| Short-term Investments | $178M | $83M | $128M | |
| Prepaid Expense | $913.0K | $6M | $1M | |
| Current Assets | $210M | $133M | $154M | |
| PP&E (Net) | $102.0K | $353.0K | $898.0K | |
| PP&E (Gross) | $7M | $7M | $7M | |
| Accum. Depreciation | $7M | $6M | $6M | |
| Other Non-current Assets | · | $568.0K | $320.0K | |
| Total Assets | $220M | $140M | $157M | |
| Accounts Payable | $2M | $2M | $4M | |
| Accrued Liabilities | $11M | $6M | $3M | |
| Current Liabilities | $14M | $9M | $8M | |
| Capital Leases | $9M | $6M | $536.0K | |
| Total Liabilities | $23M | $15M | $8M | |
| Common Stock | $18.0K | $14.0K | $13.0K | |
| Retained Earnings | $-431M | $-365M | $-315M | |
| AOCI | $280.0K | $210.0K | $37.0K | |
| Stockholders' Equity | $197M | $125M | $149M | |
| Liabilities + Equity | $220M | $140M | $157M | |
| Shares Outstanding | 178,324,000 | 137,820,000 | 127,668,000 |
Cash Flow 10
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $276.0K | $589.0K | $699.0K | |
| Stock-based Comp | $8M | $9M | $6M | |
| Operating Cash Flow | $-49M | $-45M | $-41M | |
| CapEx | $25.0K | $44.0K | $30.0K | |
| Investing Cash Flow | $-93M | $47M | $27M | |
| Stock Issued | $138M | $18M | $3M | |
| Net Stock Activity | $138M | $18M | $3M | |
| Financing Cash Flow | $130M | $17M | $3M | |
| Net Change in Cash | $-13M | $19M | $-11M | |
| Free Cash Flow | $-49M | $-45M | $-41M |
Profitability 6
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | · | -6661.8% | · | |
| Net Margin | · | -5808.8% | · | |
| EBITDA Margin | · | -6661.8% | · | |
| ROA | -36.9% | -33.2% | -23.8% | |
| ROE | -45.9% | -37.5% | -27.5% | |
| ROIC | · | · | -33.9% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 15.0 | 15.0 | 19.7 | |
| Quick Ratio | 15.0 | 14.3 | 19.5 |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $0 | $850.0K | $0 | |
| Net Income TTM | $-66M | $-49M | $-42M | |
| Market Cap | $958M | $200M | $199M | |
| P/S | · | 235.1 | · | |
| P/B | 4.9 | 1.6 | 1.3 | |
| P / Tangible Book | 4.9 | 1.6 | 1.3 | |
| P / Cash Flow | -19.5 | -4.5 | -4.9 | |
| P / FCF | -19.5 | -4.5 | -4.9 |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | · | $0 | $0 | $850.0K | · | $0 | $0 | $0 | |
| R&D Expense | · | $13M | $14M | $13M | $16M | $13M | $13M | $9M | $11M | $10M | · | · | · | |
| SG&A Expense | $7M | $7M | $4M | $3M | $5M | $5M | $4M | $4M | $5M | $3M | $3M | $3M | $3M | |
| Operating Expenses | $27M | $20M | $18M | $16M | $21M | $18M | $17M | $12M | $16M | $13M | $15M | $12M | $13M | |
| Operating Income | $-27M | $-20M | $-18M | $-16M | $-21M | $-18M | $-17M | $-12M | $-15M | $-13M | $-15M | $-12M | $-13M | |
| Interest Income | · | · | · | · | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Other Non-op | $2M | $2M | $2M | $2M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Pretax Income | · | · | · | · | · | $-17M | · | · | $-13M | $-11M | · | $-10M | $-11M | |
| Income Tax | · | · | · | · | · | $0 | · | · | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-25M | $-18M | $-16M | $-14M | $-20M | $-17M | $-15M | $-10M | $-13M | $-11M | $-13M | $-10M | $-11M | |
| EPS (Basic) | $-0.13 | $-0.10 | $-0.08 | $-0.08 | $-0.14 | $-0.12 | $-0.10 | $-0.08 | $-0.10 | $-0.08 | $-0.10 | $-0.08 | $-0.09 | |
| Shares (Basic) | 186,798,000 | 186,400,000 | -287,605,000 | 168,782,000 | 138,282,000 | 138,236,000 | -274,402,000 | 137,589,000 | 137,589,000 | 136,608,000 | -253,501,000 | 127,424,000 | 126,729,000 | |
| Shares (Diluted) | · | · | · | · | · | 138,200,000 | 100,000 | 137,600,000 | · | · | · | · | · | |
| EBITDA | $-27M | $-20M | · | $-16M | $-21M | $-18M | · | $-12M | $-15M | $-13M | · | $-12M | $-13M |
Balance Sheet 20
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $35M | $55M | $31M | $46M | $23M | $41M | $43M | $37M | $19M | $24M | $24M | $30M | $19M | |
| Short-term Investments | $144M | $140M | $178M | $174M | $78M | $72M | $83M | $99M | $127M | $133M | $128M | $133M | $149M | |
| Prepaid Expense | $1M | $1M | $913.0K | $1M | $5M | $12M | $6M | $6M | $7M | $2M | $1M | $3M | $7M | |
| Current Assets | $181M | $196M | $210M | $221M | $106M | $124M | $133M | $141M | $154M | $159M | $154M | $167M | $175M | |
| PP&E (Net) | $324.0K | $169.0K | $102.0K | $119.0K | $131.0K | $231.0K | $353.0K | $493.0K | $592.0K | $744.0K | $898.0K | $1M | $1M | |
| PP&E (Gross) | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | $7M | |
| Accum. Depreciation | $7M | $7M | $7M | $7M | $7M | $7M | $6M | $7M | $7M | $6M | $6M | $6M | $6M | |
| Other Non-current Assets | · | · | · | · | · | · | · | $568.0K | $320.0K | $320.0K | $320.0K | $320.0K | $320.0K | |
| Total Assets | $190M | $205M | $220M | $231M | $117M | $131M | $140M | $149M | $156M | $161M | $157M | $170M | $179M | |
| Accounts Payable | $3M | $906.0K | $2M | $3M | $3M | $2M | $2M | $960.0K | $1M | $854.0K | $4M | $2M | $724.0K | |
| Accrued Liabilities | $12M | $8M | $11M | $9M | $11M | $13M | $6M | $3M | $7M | $2M | $3M | $6M | $8M | |
| Current Liabilities | $16M | $10M | $14M | $12M | $14M | $15M | $9M | $4M | $10M | $4M | $8M | $9M | $10M | |
| Capital Leases | $8M | $8M | $9M | $9M | $10M | $6M | $6M | $6M | $0 | $189.0K | $536.0K | $869.0K | $1M | |
| Total Liabilities | $24M | $19M | $23M | $22M | $23M | $21M | $15M | $11M | $10M | $4M | $8M | $10M | $11M | |
| Common Stock | $18.0K | $18.0K | $18.0K | $53.0K | $14.0K | $14.0K | $14.0K | $14.0K | $14.0K | $14.0K | $13.0K | $13.0K | $13.0K | |
| Retained Earnings | $-475M | $-449M | $-431M | $-415M | $-401M | $-381M | $-365M | $-350M | $-339M | $-326M | $-315M | $-302M | $-292M | |
| AOCI | $-251.0K | $-159.0K | $280.0K | $274.0K | $208.0K | $190.0K | $210.0K | $486.0K | $-91.0K | $-90.0K | $37.0K | $-430.0K | $-507.0K | |
| Stockholders' Equity | $166M | $186M | $197M | $210M | $93M | $110M | $125M | $138M | $146M | $157M | $149M | $160M | $168M | |
| Liabilities + Equity | $190M | $205M | $220M | $231M | $117M | $131M | $140M | $149M | $156M | $161M | $157M | $170M | $179M | |
| Shares Outstanding | 180,088,000 | 180,088,000 | 178,324,000 | 177,572,000 | 138,282,000 | 138,282,000 | 137,820,000 | 137,589,000 | 137,589,000 | 137,589,000 | 127,668,000 | 127,445,000 | 127,388,000 |
Cash Flow 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $21.0K | $15.0K | $17.0K | $19.0K | $100.0K | $140.0K | $140.0K | $143.0K | $152.0K | $154.0K | $161.0K | $164.0K | $180.0K | |
| Stock-based Comp | $5M | $5M | $2M | $1M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $-15M | $-17M | $-13M | $-11M | $-12M | $-13M | $-9M | $-11M | $-11M | $-14M | $-12M | $-6M | $-10M | |
| CapEx | $176.0K | $82.0K | $0 | $7.0K | $0 | $18.0K | $0 | $44.0K | $0 | $0 | $9.0K | $10.0K | $11.0K | |
| Investing Cash Flow | $-5M | $38M | $-3M | $-95M | $-6M | $12M | $15M | $29M | $6M | $-4M | $6M | $17M | $-667.0K | |
| Stock Issued | · | · | $0 | $138M | $0 | $0 | $0 | $0 | $0 | $18M | $0 | $0 | $3M | |
| Net Stock Activity | · | · | · | · | · | $0 | · | · | · | $18M | · | · | · | |
| Financing Cash Flow | $0 | $3M | $1M | $129M | $0 | $-815.0K | $-94.0K | $-2.0K | $1.0K | $17M | $-158.0K | $21.0K | $3M | |
| Net Change in Cash | $-20M | $25M | $-16M | $23M | $-18M | $-2M | $6M | $18M | $-4M | $-554.0K | $-6M | $11M | $-8M | |
| Free Cash Flow | · | $-17M | · | · | · | $-13M | · | · | · | · | · | · | · |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | -1770.0% | · | · | · | · | |
| Net Margin | · | · | · | · | · | · | · | · | -1538.3% | · | · | · | · | |
| Pretax Margin | · | · | · | · | · | · | · | · | -1538.3% | · | · | · | · | |
| EBITDA Margin | · | · | · | · | · | · | · | · | -1770.0% | · | · | · | · | |
| ROA | -16.4% | -10.9% | · | -7.5% | -14.6% | -11.4% | · | -6.6% | -7.8% | -6.2% | · | -6.7% | -7.1% | |
| ROE | -19.4% | -12.3% | · | -8.2% | -16.6% | -12.4% | · | -7.0% | -8.3% | -6.5% | · | -7.2% | -7.6% | |
| ROIC | · | · | · | · | · | -16.3% | · | · | -10.3% | -8.1% | · | -7.4% | -7.9% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 11.2 | 19.0 | · | 17.8 | 7.7 | 8.3 | · | 31.8 | 16.2 | 40.7 | · | 18.3 | 18.1 | |
| Quick Ratio | 11.2 | 18.9 | · | 17.7 | 7.3 | 7.6 | · | 30.5 | 15.4 | 40.1 | · | 17.9 | 17.4 |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | · | · | 0.0 | 0.0 | · | · | · | · |
Valuation (TTM) 6
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-78M | $-69M | · | $-61M | $-60M | $-51M | · | $-44M | $-45M | $-40M | · | $-41M | $-40M | |
| Market Cap | $394M | $953M | · | $622M | $360M | $263M | · | $253M | $138M | $272M | · | $251M | $405M | |
| P/B | 2.4 | 5.1 | · | 3.0 | 3.9 | 2.4 | · | 1.8 | 0.9 | 1.7 | · | 1.6 | 2.4 | |
| P / Tangible Book | 2.4 | 5.1 | · | 3.0 | 3.9 | 2.4 | · | 1.8 | 0.9 | 1.7 | · | 1.6 | 2.4 | |
| P / Cash Flow | · | -55.2 | · | · | · | -19.9 | · | · | · | -19.6 | · | · | · | |
| P / FCF | · | -54.9 | · | · | · | -19.9 | · | · | · | · | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $0 | $850.0K | $0 | — | — |
| Operating Margin % | — | -6661.8% | — | — | — |
| Net Income | $-66M | $-49M | $-42M | $-39M | $-82M |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | — | — | — | — | 0.0 |
| Current Ratio | 15.0 | 15.0 | 19.7 | 12.0 | 13.8 |
| Quick Ratio | 15.0 | 14.3 | 19.5 | 11.5 | 13.6 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-49M | $-45M | $-41M | $-34M | $-21M |
Latest News Recent headlines mentioning this company
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Institutional owners (13F) 227 filers · $346.6M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 72 (+23 vs prior Q) | 42 (+22 vs prior Q) | 76 (+11 vs prior Q) | 45 (-2 vs prior Q) | -5.0M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | $39,399,813 | 17,990,782 | 11.37% | Shares |
| VANGUARD GROUP INC | $37,441,444 | 6,972,336 | 10.80% | Shares |
| ORBIMED ADVISORS LLC | $33,331,787 | 15,219,994 | 9.62% | Shares |
| MONTANOVA CAPITAL, LLC | $30,881,538 | 14,101,159 | 8.91% | Shares |
| STATE STREET CORP | $21,798,500 | 9,953,653 | 6.29% | Shares |
| ENAVATE SCIENCES GP, LLC | $17,056,049 | 7,788,150 | 4.92% | Shares |
| Vivo Capital, LLC | $16,987,961 | 7,757,060 | 4.90% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $13,400,133 | 6,118,782 | 3.87% | Shares |
| Palo Alto Investors LP | $12,771,670 | 5,831,813 | 3.68% | Shares |
| MILLENNIUM MANAGEMENT LLC | $10,322,011 | 4,713,247 | 2.98% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $8,258,560 | 3,771,032 | 2.38% | Shares |
| Qube Research & Technologies Ltd | $8,075,601 | 3,687,489 | 2.33% | Shares |
| Blue Owl Capital Holdings LP | $7,936,726 | 3,624,076 | 2.29% | Shares |
| Rock Springs Capital Management LP | $7,719,595 | 3,524,929 | 2.23% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $7,167,845 | 3,271,990 | 2.07% | Shares |
| GOLDMAN SACHS GROUP INC | $5,881,777 | 2,685,743 | 1.70% | Shares |
| Birchview Capital, LP | $3,668,250 | 1,675,000 | 1.06% | Shares |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $3,066,000 | 1,400,000 | 0.88% | Shares |
| Fisher Asset Management, LLC | $3,048,238 | 1,391,890 | 0.88% | Shares |
| ROYCE & ASSOCIATES LP | $2,927,548 | 1,336,780 | 0.84% | Shares |
| FMR LLC | $2,654,709 | 1,212,196 | 0.77% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $2,598,435 | 1,186,500 | 0.75% | Shares |
| Atle Fund Management AB | $2,296,418 | 1,048,593 | 0.66% | Shares |
| Squarepoint Ops LLC | $2,206,440 | 1,007,507 | 0.64% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $2,192,054 | 1,000,938 | 0.63% | Shares |
| Blackstone Inc. | $1,970,860 | 899,936 | 0.57% | Shares |
| FIRST TRUST ADVISORS LP | $1,767,338 | 807,004 | 0.51% | Shares |
| KVP Capital Advisors, LP | $1,688,490 | 771,000 | 0.49% | Shares |
| UBS Group AG | $1,560,951 | 712,763 | 0.45% | Shares |
| CITIGROUP INC | $1,546,887 | 706,341 | 0.45% | Shares |
| Burkehill Global Management, LP | $1,533,000 | 700,000 | 0.44% | Shares |
| JPMORGAN CHASE & CO | $1,505,377 | 696,934 | 0.43% | Shares |
| Point72 Asset Management, L.P. | $1,503,604 | 686,577 | 0.43% | Shares |
| ACUTA CAPITAL PARTNERS, LLC | $1,303,516 | 595,213 | 0.38% | Shares |
| CM Management, LLC | $1,204,500 | 550,000 | 0.35% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $1,147,072 | 523,777 | 0.33% | Shares |
| MORGAN STANLEY | $1,088,441 | 497,005 | 0.31% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $1,045,092 | 477,211 | 0.30% | Shares |
| BANK OF AMERICA CORP /DE/ | $994,089 | 453,922 | 0.29% | Shares |
| ALLIANCEBERNSTEIN L.P. | $856,345 | 161,880 | 0.25% | Shares |
| Artia Global Partners LP | $839,208 | 383,200 | 0.24% | Shares |
| ArrowMark Colorado Holdings LLC | $798,785 | 364,742 | 0.23% | Shares |
| TWO SIGMA INVESTMENTS, LP | $701,483 | 320,312 | 0.20% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $675,166 | 308,295 | 0.19% | Shares |
| ALGERT GLOBAL LLC | $674,761 | 308,110 | 0.19% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $663,874 | 303,139 | 0.19% | Shares |
| NATIXIS | $651,996 | 297,715 | 0.19% | Shares |
| Exome Asset Management LLC | $604,801 | 276,165 | 0.17% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $594,152 | 112,316 | 0.17% | Shares |
| Caption Management, LLC | $577,234 | 263,577 | 0.17% | Shares |
| TEMA ETFS LLC | $537,945 | 100,176 | 0.16% | Shares |
| Seven Fleet Capital Management LP | $510,415 | 233,066 | 0.15% | Shares |
| DV EQUITIES, LLC | $510,415 | 233,066 | 0.15% | Shares |
| PANAGORA ASSET MANAGEMENT INC | $486,572 | 222,179 | 0.14% | Shares |
| XTX Topco Ltd | $476,292 | 217,485 | 0.14% | Shares |
| Orion Porfolio Solutions, LLC | $468,360 | 213,863 | 0.14% | Shares |
| Optimize Financial Inc | $425,522 | 80,439 | 0.12% | Shares |
| Rafferty Asset Management, LLC | $416,376 | 190,126 | 0.12% | Shares |
| ALPS ADVISORS INC | $400,282 | 182,777 | 0.12% | Shares |
| Mariner, LLC | $378,432 | 172,821 | 0.11% | Shares |
| Swiss National Bank | $376,023 | 171,700 | 0.11% | Shares |
| JANE STREET GROUP, LLC | $372,300 | 170,000 | 0.11% | Call option |
| Virtus Investment Advisers, LLC | $352,986 | 161,181 | 0.10% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $352,371 | 160,900 | 0.10% | Shares |
| RHUMBLINE ADVISERS | $346,984 | 158,444 | 0.10% | Shares |
| JANUS HENDERSON GROUP PLC | $293,846 | 55,600 | 0.08% | Shares |
| IEQ CAPITAL, LLC | $269,256 | 122,948 | 0.08% | Shares |
| ADAR1 Capital Management, LLC | $267,469 | 122,132 | 0.08% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $249,165 | 113,774 | 0.07% | Shares |
| Bank of New York Mellon Corp | $242,878 | 110,903 | 0.07% | Shares |
| WELLS FARGO & COMPANY/MN | $240,447 | 109,793 | 0.07% | Shares |
| Quadrature Capital Ltd | $237,068 | 108,250 | 0.07% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $233,388 | 106,570 | 0.07% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $230,198 | 105,113 | 0.07% | Shares |
| PROFUND ADVISORS LLC | $208,508 | 95,209 | 0.06% | Shares |
| Schonfeld Strategic Advisors LLC | $201,975 | 92,227 | 0.06% | Shares |
| TUDOR INVESTMENT CORP ET AL | $197,196 | 90,044 | 0.06% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $194,711 | 83,567 | 0.06% | Shares |
| Jain Global LLC | $193,381 | 88,302 | 0.06% | Shares |
| SmartHarvest Portfolios, LLC | $189,453 | 86,508 | 0.05% | Shares |
| GROUP ONE TRADING LLC | $178,610 | 81,557 | 0.05% | Shares |
| BlackRock, Inc. | $178,213 | 81,376 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $177,390 | 81,000 | 0.05% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $163,569 | 74,689 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $161,622 | 73,800 | 0.05% | Call option |
| MetLife Investment Management, LLC | $156,412 | 71,421 | 0.05% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $149,395 | 68,217 | 0.04% | Shares |
| ExodusPoint Capital Management, LP | $147,777 | 67,478 | 0.04% | Shares |
| CITADEL ADVISORS LLC | $143,445 | 65,500 | 0.04% | Put option |
| D. E. Shaw & Co., Inc. | $141,612 | 64,663 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $133,936 | 61,158 | 0.04% | Shares |
| Wealthcare Advisory Partners LLC | $133,507 | 60,962 | 0.04% | Shares |
| Quantbot Technologies LP | $133,209 | 60,826 | 0.04% | Shares |
| JANE STREET GROUP, LLC | $131,301 | 59,955 | 0.04% | Shares |
| SIMPLEX TRADING, LLC | $126,560 | 57,790 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $123,078 | 56,200 | 0.04% | Put option |
| Focus Partners Wealth | $116,335 | 53,121 | 0.03% | Shares |
| Invesco Ltd. | $114,701 | 52,375 | 0.03% | Shares |
| Sequoia Financial Advisors, LLC | $98,507 | 44,980 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $96,172 | 43,914 | 0.03% | Shares |
Company insiders 18 insiders · 8 officers · 12 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Thomas J. Schuetz | CHIEF EXECUTIVE OFFICER | Feb. 8, 2026 F | 6,603,336 | 0 | 0 | $0 |
| Vered Bisker-Leib | CHIEF EXECUTIVE OFFICER | Feb. 8, 2024 F | 3,124,426 | 0 | 0 | $0 |
| Barry Shin | CFO | Jan. 2, 2026 A | 525,000 | 0 | 0 | $0 |
| Jonathan Anderman | General Counsel | April 29, 2026 P | 196,000 | 1 | 0 | $47,250 |
| Neil Lerner | Chief Accounting Officer | April 29, 2026 P | 397,500 | 1 | 0 | $28,350 |
| Arjun Prasad | Chief Commercial Officer | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Cynthia Sirard | Chief Medical Officer | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Susan Kalled | Chief Scientific Officer | Feb. 18, 2022 A | — | 0 | 0 | $0 |
| James P Boylan | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Philip Ferneau | Director | Jan. 2, 2026 A | 400,280 | 0 | 0 | $0 |
| Ellen Chiniara | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| GORDON CARL L | Director | Jan. 2, 2026 A | 0 | 0 | 0 | $0 |
| Mary Ann Gray | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Richard S Lindahl | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| David M Wurzer | Director | Feb. 8, 2023 A | — | 0 | 0 | $0 |
| Brett Kaplan | Director | Feb. 18, 2022 A | — | 0 | 0 | $0 |
| Stephen P Squinto | Director | Feb. 18, 2022 A | — | 0 | 0 | $0 |
| Julie Sunderland | Director | June 19, 2020 P | 2,502,025 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 5 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Commander Aggregator, LP, Enavate Sciences, LP, Enavate Sciences GP, LLC, Enavate Sciences Holdings, LLC | Aug. 18, 2025 | 4.50% | Amendment | — | SEC |
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP V LLC ×7 filings | Aug. 15, 2025 | 8.90% | Amendment | — | SEC |
| Undisclosed reporting person | Nov. 14, 2022 | — | Initial filing | — | SEC |
| Philip Ferneau, Vox Health Fund, L.P., Borealis Capital Partners IV, LLC, Borealis Granite Fund, L.P., Borealis Capital Partners III, LLC | June 26, 2020 | — | Initial filing | — | SEC |
| Thomas J. Schuetz | June 26, 2020 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 30 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0.27% | 185,633 NS | May 31, 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0.25% | 53,489 NS | April 30, 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0.07% | 441,490 NS | April 30, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.07% | 210,822 NS | April 30, 2026 | N-PORT |
| IWC · iShares Trust | 0.06% | 448,663 SH | Aug. 8, 2026 | Daily |
| FYX · First Trust Exchange-Traded AlphaDE… | 0.04% | 261,767 NS | April 30, 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.02% | 114,090 SH | Aug. 8, 2026 | Daily |
| IWN · iShares Trust | 0.02% | 1,200,652 SH | Aug. 8, 2026 | Daily |
| FAD · First Trust Exchange-Traded AlphaDE… | 0.02% | 41,165 NS | April 30, 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.01% | 46,574 NS | May 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 754,118 SH | Aug. 8, 2026 | Daily |
| IWM · iShares Trust | 0.01% | 3,388,508 SH | Aug. 8, 2026 | Daily |
| ITWO · ProShares Trust | 0.01% | 6,071 NS | May 31, 2026 | N-PORT |
| RSSL · Global X Funds | 0.01% | 55,815 NS | April 30, 2026 | N-PORT |
| UWM · ProShares Trust | 0.00% | 4,749 NS | May 31, 2026 | N-PORT |
| URTY · ProShares Trust | 0.00% | 4,800 NS | May 31, 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.00% | 51,153 NS | April 30, 2026 | N-PORT |
| WSML · iShares Trust | 0.00% | 6,789 SH | Aug. 8, 2026 | Daily |
| ONEQ · Fidelity Commonwealth Trust | 0.00% | 64,580 NS | May 31, 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 4,596 NS | May 31, 2026 | N-PORT |
| HDG · ProShares Trust | 0.00% | 121 NS | May 31, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 244,958 SH | Aug. 8, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.00% | 28,557 NS | April 30, 2026 | N-PORT |
| IWV · iShares Trust | 0.00% | 33,872 SH | Aug. 8, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 1,793,659 SH | Aug. 8, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 4,190,754 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 11,073 SH | Aug. 8, 2026 | Daily |
| DFAU · Dimensional ETF Trust | 0.00% | 2,437 NS | April 30, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 7,766 NS | April 30, 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0.00% | 257,838 SH | Aug. 8, 2026 | Daily |