EDIT Editas Medicine, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$3.19
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026

About Editas Medicine, Inc. - Common Stock Company overview from Wikipedia

Editas Medicine, Inc.,, is a clinical-stage biotechnology company which is developing therapies for rare diseases based on CRISPR gene editing technology. Editas headquarters is located in Cambridge, Massachusetts and has facilities in Boulder, Colorado.

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Editas Medicine, Inc., (formerly Gengine, Inc.), is a clinical-stage biotechnology company which is developing therapies for rare diseases based on CRISPR gene editing technology. Editas headquarters is located in Cambridge, Massachusetts and has facilities in Boulder, Colorado.

History

Editas Medicine was originally founded with the name "Gengine, Inc." in September 2013 by Feng Zhang of the Broad Institute, Jennifer Doudna of the University of California, Berkeley, and George Church, David Liu, and J. Keith Joung of Harvard University, with funding from Third Rock Ventures, Polaris Partners and Flagship Ventures. The name was changed to the current "Editas Medicine" two months later. Doudna quit in June 2014 over legal differences concerning intellectual property of Cas9.

In August 2015, the company raised $120 million in Series B funding from Bill Gates and 13 other investors. it went public on 2 February 2016, via a $94 million initial public offering.

Editas entered into a strategic collaboration with Juno Therapeutics in 2015 to create a chimeric antigen receptor and high-affinity T cell receptor therapeutics to the end of developing cancer therapeutics. Juno was later acquired by Celgene, which was in turn acquired by Bristol Myers Squibb.

The company announced in 2015 that it was planning a clinical trial using CRISPR gene editing techniques to treat Leber congenital amaurosis type 10 (LCA10), a rare genetic illness that causes blindness. On 30 November 2018, the FDA gave permission to start the trials, under the investigational name EDIT-101 (also known as AGN-151587). In September 2021, a statement from Editas claimed that preliminary results from clinical trials were promising and support clinical benefits of EDIT-101 treatment.

In March 2020, Editas, in partnership with Allergan, was the first to use CRISPR to try to edit DNA inside a person's body (in vivo). As part of the clinical trial, a patient who was nearly blind as a result of Leber's congenital amaurosis received an intravitreal injection containing a harmless virus carrying CRISPR gene-editing instructions. Five months later, Editas reworked its deal with Allergan's owner AbbVie and regained full rights to their range of eye disease treatment therapies, including EDIT-101 for the treatment of LCA10.

In 2019, the company was building new chemistry facilities in Boulder, Colorado.

Katrine Bosley was CEO until 2019, when she was replaced by board member Cynthia Collins. Collins was replaced in 2021 by James Mullen, who had been board chairman. Gilmore O'Neill, former CMO of Sarepta Therapeutics, became CEO on June 1, 2022, with Mullen staying on as executive chairman of the board.

On December 12, 2024, Editas ended the development of reni-cel and laid off 65% of its employees.

Research

Editas works with two different CRISPR nucleases, Cas9 and Cas12a.

EDIT-101 is a CRISPR based gene therapy for treatment of Leber congenital amaurosis, currently in clinical trials.

EDIT-301 is an experimental potential treatment utilizing the firm's CAS 12a editing technology for sickle cell disease and beta-thalassemia. In 2019 the firm reported early success in research on the drug;. In December 2020, it filed an IND application for treatment of sickle cell disease. In January 2021, it said it had received clearance from the FDA for phase 1 safety studies.

== References ==

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

EDIT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$3.19
Market Cap
$312M
P/E (TTM)
-1.8
EPS (TTM)
$-1.80
Revenue (TTM)
$41M
Div Yield
ROE
-688.8%
Debt/Equity
2.1
52W Range
$2 – $5

EDIT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $41M
10-point trend, +569.4%
2016-12-31 2025-12-31
EPS $-1.80
7-point trend, +32.8%
2019-12-31 2025-12-31
Free Cash Flow $-166M
10-point trend, -210.5%
2016-12-31 2025-12-31
Margins -395.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
EDIT
Peer Median
P/E (TTM)
5-point trend, +87.8%
-1.8
17.4
P/S (TTM)
5-point trend, -93.0%
7.7
52.3
P/B
5-point trend, +124.0%
11.4
4.8
EV / EBITDA
2-point trend, -264.5%
-1.4
Price / FCF
5-point trend, +88.6%
-1.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
EDIT
Peer Median
Operating Margin
5-point trend, +47.8%
-394.9%
Net Profit Margin
5-point trend, +47.6%
-395.0%
-670.1%
ROA
5-point trend, -96.8%
-60.6%
-41.1%
ROE
5-point trend, -1940.2%
-688.8%
-52.6%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
EDIT
Peer Median
Debt / Equity
2-point trend, +402.1%
2.1
Current Ratio
5-point trend, -67.2%
3.5
7.7
Quick Ratio
5-point trend, -67.2%
3.5

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
EDIT
Peer Median
Revenue YoY
5-point trend, +58.6%
25.4%
Revenue CAGR 3Y
5-point trend, +58.6%
27.2%
Revenue CAGR 5Y
5-point trend, +58.6%
-14.9%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
EDIT
Peer Median
EPS (Diluted)
5-point trend, +36.8%
$-1.80

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
EDIT
Peer Median

EDIT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 18 analysts
  • Strong Buy 4 22.2%
  • Buy 8 44.4%
  • Hold 4 22.2%
  • Sell 2 11.1%
  • Strong Sell 0 0.0%

12-Month Price Target

8 analysts · 2026-08-16
Median target $5.00 +57.0%
Mean target $6.00 +88.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.03%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.15 $-0.28 0.13%
March 31, 2026 $-0.26 $-0.27 0.01%
Dec. 31, 2025 $-0.06 $-0.26 0.20%
Sept. 30, 2025 $-0.28 $-0.30 0.02%
June 30, 2025 $-0.63 $-0.38 -0.25%
March 31, 2025 $-0.92 $-0.60 -0.32%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
EDIT $201M -1.1 25.4% -395.0% -688.8%
CABA $220M -1.0 -115.5%
VSTM $600M -2.6 209.1% -677.6% -449.2%
ZURA
MPLT $773M -0.9 -151.1%
OCGN $422M -5.6 8.8% -1537.4% 1488.8%
PBYI $300M 9.8 -0.91% 13.6% 26.5%
QTTB $43M 1.4 55.5% 200.3%
RZLT $388M -4.6 -56.9%
CMPX $958M -45.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 13
Annual Income Statement data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Revenue 10-point trend, +569.4% $41M $32M $78M $20M $26M $91M $21M $32M $14M $6M
R&D Expense 10-point trend, +57.9% $90M $199M $178M $175M $143M $158M $97M $91M $83M $57M
SG&A Expense 10-point trend, +7.9% $50M $72M $70M $71M $76M $68M $65M $55M $51M $46M
Operating Expenses 10-point trend, +94.2% $201M $283M $247M $246M $219M $226M $161M $146M $134M $103M
Operating Income 10-point trend, -64.6% $-160M $-251M $-169M $-226M $-193M $-135M $-141M $-114M $-120M $-97M
Other Non-op 10-point trend, -3740.4% $-2M $-3.0K $-2M $0 $37.0K $16M $-137.0K $328.0K $587.0K $-57.0K
Income Tax Flat — no change across 5 periods $0 $0 $0 $0 $0 · · · · ·
Net Income 10-point trend, -64.7% $-160M $-237M $-153M $-220M $-193M $-116M $-134M $-110M $-120M $-97M
EPS (Basic) 7-point trend, +32.8% $-1.80 $-2.88 $-2.02 $-3.21 $-2.85 $-1.98 $-2.68 · · ·
EPS (Diluted) 7-point trend, +32.8% $-1.80 $-2.88 $-2.02 $-3.21 $-2.85 $-1.98 $-2.68 · · ·
Shares (Basic) 7-point trend, +77.6% 88,745,908 82,338,220 75,965,633 68,664,822 67,619,388 58,609,389 49,983,329 · · ·
Shares (Diluted) 7-point trend, +77.6% 88,745,908 82,338,220 75,965,633 68,664,822 67,619,388 58,609,389 49,983,329 · · ·
EBITDA 10-point trend, -64.6% $-160M $-251M $-169M $-226M $-193M $-135M $-141M $-114M $-120M $-97M
Balance Sheet 24
Annual Balance Sheet data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents 10-point trend, -20.9% $147M $132M $124M $142M $204M $140M $238M $135M $147M $185M
Short-term Investments 9-point trend, -100.0% $0 $138M $199M $203M $296M $262M $219M $234M $183M ·
Receivables 10-point trend, +17145.5% $15M $16M $10M $5M $267.0K $6M $418.0K $30.0K $679.0K $88.0K
Prepaid Expense 10-point trend, +17.0% $2M $3M $8M $7M $7M $11M $6M $6M $2M $2M
Current Assets 10-point trend, -12.4% $164M $289M $341M $357M $507M $419M $464M $375M $332M $187M
PP&E (Net) 10-point trend, -91.2% $4M $14M $12M $16M $17M $14M $11M $40M $39M $40M
PP&E (Gross) 10-point trend, -23.9% $32M $46M $38M $37M $33M $25M $18M $47M $44M $42M
Accum. Depreciation 10-point trend, +1722.2% $28M $32M $26M $22M $16M $11M $7M $7M $4M $2M
Other Non-current Assets 10-point trend, +83.6% $3M $5M $9M $5M $7M $5M $5M $5M $2M $2M
Total Assets 10-point trend, -18.6% $187M $342M $499M $514M $677M $573M $509M $420M $373M $229M
Accounts Payable 10-point trend, -43.9% $3M $5M $8M $10M $5M $6M $6M $5M $4M $5M
Accrued Liabilities 10-point trend, +87.0% $33M $46M $35M $31M $20M $24M $22M $13M $11M $17M
Current Liabilities 10-point trend, +39.8% $46M $77M $63M $60M $47M $58M $60M $36M $37M $33M
Capital Leases 10-point trend, -65.6% $12M $20M $24M $33M $16M $19M $23M $32M $33M $35M
Other Non-current Liabilities 9-point trend, +610.9% $3M $3M $2M $0 · $28M $1.0K $293.0K $317.0K $396.0K
Total Liabilities 10-point trend, +68.4% $159M $207M $150M $154M $124M $179M $246M $184M $165M $95M
Long-term Debt 3-point trend, +58605000.00 $59M $57M $0 · · · · · · ·
Total Debt 2-point trend, +2.0% $59M $57M · · · · · · · ·
Common Stock 10-point trend, +150.0% $10.0K $8.0K $8.0K $7.0K $7.0K $6.0K $5.0K $5.0K $4.0K $4.0K
Retained Earnings 10-point trend, -777.8% $-1.63B $-1.47B $-1.23B $-1.08B $-858M $-665M $-549M $-416M $-306M $-186M
AOCI 9-point trend, +100.0% $0 $268.0K $198.0K $-4M $-493.0K $-46.0K $107.0K $-29.0K $-76.0K ·
Stockholders' Equity 10-point trend, -79.7% $27M $134M $349M $361M $554M $394M $262M $236M $208M $135M
Liabilities + Equity 10-point trend, -18.6% $187M $342M $499M $514M $677M $573M $509M $420M $373M $229M
Shares Outstanding 10-point trend, +173.2% 97,866,996 82,734,696 81,767,263 68,847,382 68,435,257 62,563,457 54,355,798 48,758,951 44,507,960 35,818,131
Cash Flow 10
Annual Cash Flow data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Stock-based Comp 10-point trend, -40.8% $10M $21M $20M $29M $43M $23M $27M $27M $23M $17M
Restructuring 3-point trend, +12232000.00 · $12M $0 $0 · · · · · ·
Operating Cash Flow 10-point trend, -228.9% $-165M $-210M $-132M $-177M $-164M $-180M $-41M $-46M $-9M $-50M
CapEx 10-point trend, -82.6% $607.0K $9M $5M $4M $8M $7M $6M $5M $2M $3M
Investing Cash Flow 10-point trend, +4092.7% $139M $162M $-4M $114M $-54M $-141M $12M $-53M $-184M $-3M
Stock Issued 10-point trend, -56.0% $43M $0 $117M $0 $249M $204M $116M $77M $154M $97M
Net Stock Activity 9-point trend, -56.0% $43M $0 $117M · $249M $204M $116M $77M $154M $97M
Financing Cash Flow 10-point trend, -58.3% $40M $56M $118M $1M $282M $224M $132M $87M $155M $97M
Net Change in Cash 10-point trend, -68.0% $14M $8M $-18M $-62M $64M $-96M $103M $-12M $-39M $43M
Free Cash Flow 10-point trend, -210.5% $-166M $-219M $-137M $-181M $-172M $-187M $-47M $-50M $-11M $-53M
Profitability 5
Annual Profitability data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Operating Margin 8-point trend, -10.9% -394.9% -777.2% -216.6% -1146.3% -756.1% -148.6% -686.4% -356.1% · ·
Net Margin 8-point trend, -14.7% -395.0% -733.7% -196.1% -1118.3% -753.6% -127.8% -651.4% -344.3% · ·
EBITDA Margin 8-point trend, -10.9% -394.9% -777.2% -216.6% -1146.3% -756.1% -148.6% -686.4% -356.1% · ·
ROA 10-point trend, -18.0% -60.6% -56.4% -30.2% -37.0% -30.8% -21.4% -28.8% -27.7% -40.0% -51.3%
ROE 10-point trend, -82.5% -688.8% -153.0% -43.2% -56.9% -33.8% -27.8% -56.6% -47.7% -70.2% -377.5%
Liquidity & Solvency 4
Annual Liquidity & Solvency data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 10-point trend, -37.4% 3.5 3.7 5.4 5.9 10.8 7.2 7.7 10.4 9.1 5.7
Quick Ratio 10-point trend, -37.6% 3.5 3.7 5.3 5.8 10.7 7.0 7.6 10.3 9.0 5.6
Debt / Equity 2-point trend, +402.1% 2.1 0.4 · · · · · · · ·
LT Debt / Equity 2-point trend, +403.0% 2.0 0.4 · · · · · · · ·
Efficiency 2
Annual Efficiency data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Asset Turnover 8-point trend, +90.6% 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 · ·
Receivables Turnover 8-point trend, -97.1% 2.6 2.4 10.2 7.3 8.1 28.1 91.7 90.1 · ·
Per Share 5
Annual Per Share data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Book Value / Share 10-point trend, -92.6% $0.28 $1.62 $4.27 $5.24 $8.09 $6.29 $4.83 $4.84 $4.68 $3.76
Revenue / Share 5-point trend, +20.9% $0.46 $0.39 $1.03 $0.29 $0.38 · · · · ·
Cash Flow / Share 5-point trend, +23.1% $-1.86 $-2.55 $-1.74 $-2.58 $-2.42 · · · · ·
Cash / Share 10-point trend, -71.0% $1.50 $1.59 $1.51 $2.06 $2.97 $2.23 $4.38 $2.76 $3.29 $5.17
EPS (TTM) 7-point trend, +32.8% $-1.80 $-2.88 $-2.02 $-3.21 $-2.85 $-1.98 $-2.68 · · ·
Growth Rates 3
Annual Growth Rates data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Revenue YoY 5-point trend, +135.3% 25.4% -58.6% 296.3% -22.8% -71.9% · · · · ·
Revenue CAGR 3Y 3-point trend, +657.5% 27.2% 8.2% -4.9% · · · · · · ·
Revenue CAGR 5Y -14.9% · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for EDIT
Metric Trend 2025202420232022202120202019201820172016
Revenue TTM 10-point trend, +569.4% $41M $32M $78M $20M $26M $91M $21M $32M $14M $6M
Net Income TTM 10-point trend, -64.7% $-160M $-237M $-153M $-220M $-193M $-116M $-134M $-110M $-120M $-97M
Market Cap 10-point trend, -65.5% $201M $105M $828M $611M $1.82B $4.39B $1.61B $1.11B $1.37B $581M
Enterprise Value 2-point trend, +204.8% $113M $-107M · · · · · · · ·
P/E 7-point trend, +89.7% -1.1 -0.4 -5.0 -2.8 -9.3 -35.4 -11.0 · · ·
P/S 10-point trend, -94.8% 5.0 3.3 10.6 31.0 71.1 48.3 78.4 34.7 99.6 96.0
P/B 10-point trend, +70.2% 7.4 0.8 2.4 1.7 3.3 11.1 6.1 4.7 6.6 4.3
P / Tangible Book 6-point trend, -34.0% 7.4 0.8 2.4 1.7 3.3 11.1 · · · ·
P / Cash Flow 10-point trend, +89.6% -1.2 -0.5 -6.3 -3.4 -11.1 -24.4 -39.6 -24.3 -145.2 -11.6
P / FCF 10-point trend, +88.9% -1.2 -0.5 -6.1 -3.4 -10.6 -23.5 -34.4 -22.0 -119.2 -10.9
EV / EBITDA 2-point trend, -264.5% -0.7 0.4 · · · · · · · ·
EV / FCF 2-point trend, -238.5% -0.7 0.5 · · · · · · · ·
EV / Revenue 2-point trend, +183.6% 2.8 -3.3 · · · · · · · ·
Earnings Yield 7-point trend, -870.2% -87.8% -226.8% -19.9% -36.2% -10.7% -2.8% -9.0% · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $41M$32M$78M$20M$26M
Operating Margin % -394.9%-777.2%-216.6%-1146.3%-756.1%
Net Income $-160M$-237M$-153M$-220M$-193M
Diluted EPS $-1.80$-2.88$-2.02$-3.21$-2.85
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 2.10.4
Current Ratio 3.53.75.45.910.8
Quick Ratio 3.53.75.35.810.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-166M$-219M$-137M$-181M$-172M

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Institutional owners (13F) 239 filers · $327.2M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
41 (-2 vs prior Q) 22 (-4 vs prior Q) 76 (+20 vs prior Q) 42 (-9 vs prior Q) +67.4M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
TCG Crossover Management, LLC $36,000,000 11,111,111 11.00% Shares
RA CAPITAL MANAGEMENT, L.P. $28,800,360 8,889,000 8.80% Shares
Commodore Capital LP $28,800,360 8,889,000 8.80% Shares
ADAR1 Capital Management, LLC $28,800,360 8,889,000 8.80% Shares
VANGUARD CAPITAL MANAGEMENT LLC $19,897,929 6,141,336 6.08% Shares
Paradigm Biocapital Advisors LP $18,100,665 5,586,625 5.53% Shares
Opaleye Management Inc. $12,512,653 3,861,930 3.82% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $11,658,618 3,598,339 3.56% Shares
Woodline Partners LP $11,519,810 3,555,497 3.52% Shares
Vivo Capital, LLC $11,519,010 3,555,250 3.52% Shares
GordonMD Global Investments LP $10,131,480 3,127,000 3.10% Shares
RENAISSANCE TECHNOLOGIES LLC $7,999,298 2,468,919 2.45% Shares
Logos Global Management LP $7,199,280 2,222,000 2.20% Shares
GEODE CAPITAL MANAGEMENT, LLC $7,134,030 2,201,290 2.18% Shares
STATE STREET CORP $7,101,442 2,191,803 2.17% Shares
GOLDMAN SACHS GROUP INC $6,763,843 2,087,606 2.07% Shares
TWO SIGMA INVESTMENTS, LP $4,318,842 1,332,976 1.32% Shares
Seven Fleet Capital Management LP $4,310,820 1,330,500 1.32% Shares
RAYMOND JAMES FINANCIAL INC $4,201,156 1,296,653 1.28% Shares
MARSHALL WACE, LLP $4,044,048 1,248,163 1.24% Shares
D. E. Shaw & Co., Inc. $3,715,178 1,146,660 1.14% Shares
KENNEDY CAPITAL MANAGEMENT LLC $3,344,111 1,032,133 1.02% Shares
MACKENZIE FINANCIAL CORP $2,844,856 878,042 0.87% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $2,812,424 868,032 0.86% Shares
Nantahala Capital Management, LLC $2,762,748 852,700 0.84% Shares
TWO SIGMA ADVISERS, LP $2,509,405 1,224,100 0.77% Shares
VANGUARD FIDUCIARY TRUST CO $2,407,158 742,950 0.74% Shares
BlackRock, Inc. $1,813,920 559,852 0.55% Shares
MILLENNIUM MANAGEMENT LLC $1,616,750 498,997 0.49% Shares
Susquehanna Portfolio Strategies, LLC $1,545,801 477,099 0.47% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,521,180 469,500 0.46% Call option
Eversept Partners, LP $1,486,541 458,809 0.45% Shares
Casdin Capital, LLC $1,441,800 445,000 0.44% Shares
PEAK6 LLC $1,346,029 415,441 0.41% Shares
DIADEMA PARTNERS LP $1,296,000 400,000 0.40% Call option
BIT Capital GmbH $1,056,240 326,000 0.32% Shares
Cubist Systematic Strategies, LLC $994,094 286,482 0.30% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $878,642 271,186 0.27% Shares
BANK OF AMERICA CORP /DE/ $751,119 231,827 0.23% Shares
LPL Financial LLC $748,813 231,115 0.23% Shares
Erste Asset Management GmbH $736,000 230,000 0.22% Shares
IEQ CAPITAL, LLC $705,623 217,785 0.22% Shares
Walleye Capital LLC $595,703 183,859 0.18% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $558,900 172,500 0.17% Put option
CITADEL ADVISORS LLC $557,604 172,100 0.17% Put option
DAFNA Capital Management LLC $552,323 170,470 0.17% Shares
Mariner, LLC $548,500 169,291 0.17% Shares
Green Alpha Advisors, LLC $505,589 156,046 0.15% Shares
PEAK6 LLC $497,340 153,500 0.15% Call option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $490,555 151,406 0.15% Shares
BARCLAYS PLC $476,030 146,923 0.15% Shares
ALLIANCEBERNSTEIN L.P. $464,187 187,930 0.14% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $445,030 137,355 0.14% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $408,240 126,000 0.12% Shares
Point72 Asset Management, L.P. $405,758 125,234 0.12% Shares
RHUMBLINE ADVISERS $380,421 117,417 0.12% Shares
JPMORGAN CHASE & CO $376,528 117,665 0.12% Shares
JANE STREET GROUP, LLC $374,473 115,578 0.11% Shares
FMR LLC $348,384 107,526 0.11% Shares
HSBC HOLDINGS PLC $314,481 97,062 0.10% Shares
Bank of New York Mellon Corp $309,378 95,487 0.09% Shares
WELLINGTON MANAGEMENT GROUP LLP $303,462 93,661 0.09% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $300,818 92,845 0.09% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $300,226 92,094 0.09% Shares
AMERICAN CENTURY COMPANIES INC $300,011 92,596 0.09% Shares
CWM, LLC $259,352 105,001 0.08% Shares
MORGAN STANLEY $237,324 73,248 0.07% Shares
CITADEL ADVISORS LLC $229,392 70,800 0.07% Call option
OSAIC HOLDINGS, INC. $222,928 68,806 0.07% Shares
SEI INVESTMENTS CO $221,188 68,268 0.07% Shares
Nuveen, LLC $221,188 68,268 0.07% Shares
Joel Isaacson & Co., LLC $220,787 68,144 0.07% Shares
JANE STREET GROUP, LLC $218,376 67,400 0.07% Put option
SIMPLEX TRADING, LLC $207,275 63,974 0.06% Shares
MetLife Investment Management, LLC $182,140 56,216 0.06% Shares
CITIGROUP INC $182,052 56,189 0.06% Shares
CITADEL ADVISORS LLC $173,923 53,680 0.05% Shares
MML INVESTORS SERVICES, LLC $168,765 52,088 0.05% Shares
GROUP ONE TRADING LLC $163,131 50,349 0.05% Shares
Creative Planning $147,653 45,572 0.05% Shares
China Universal Asset Management Co., Ltd. $143,934 44,424 0.04% Shares
WINTON GROUP Ltd $141,588 43,700 0.04% Shares
Vanguard Global Advisers, LLC $138,876 42,863 0.04% Shares
CANADA PENSION PLAN INVESTMENT BOARD $137,376 42,400 0.04% Shares
Graham Capital Management, L.P. $134,369 41,472 0.04% Shares
Quinn Opportunity Partners LLC $129,600 40,000 0.04% Shares
Invesco Ltd. $128,178 39,561 0.04% Shares
Vanguard Personalized Indexing Management, LLC $124,108 38,305 0.04% Shares
MERCER GLOBAL ADVISORS INC /ADV $121,967 37,644 0.04% Shares
Balyasny Asset Management L.P. $121,947 37,638 0.04% Shares
AXQ CAPITAL, LP $118,104 36,452 0.04% Shares
Nuveen Asset Management, LLC $113,934 89,712 0.03% Shares
SCS Capital Management LLC $113,400 35,000 0.03% Shares
Police & Firemen's Retirement System of New Jersey $109,749 33,873 0.03% Shares
Thrive Wealth Management, LLC $108,540 33,500 0.03% Shares
TWO SIGMA SECURITIES, LLC $107,367 33,138 0.03% Shares
INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC $102,359 31,207 0.03% Shares
CAPTRUST FINANCIAL ADVISORS $98,159 30,296 0.03% Shares
HORIZON KINETICS ASSET MANAGEMENT LLC $89,683 27,680 0.03% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $88,339 27,265 0.03% Shares

Company insiders 32 insiders · 13 officers · 15 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Gilmore Neil O'Neill CEO June 3, 2026 S 248,313 0 1 $-41,543
MULLEN JAMES C CEO Jan. 3, 2022 S 75,898 0 0 $0
Cynthia Collins CEO Feb. 9, 2021 S 43,760 0 0 $0
Katrine Bosley President and CEO Jan. 8, 2019 S 1,204,966 0 0 $0
Michelle Robertson Chief Financial Officer Jan. 11, 2022 S 31,462 0 0 $0
Andrew A. F. Hack Chief Financial Officer Feb. 4, 2019 M 0 0 0 $0
Linda Burkly EVP, CHIEF SCIENTIFIC OFFICER July 28, 2026 S 62,369 0 2 $-15,133
Bruce Eaton EVP, Chief Business Officer Dec. 22, 2021 A 31,498 0 0 $0
Lisa Anne Michaels EVP/Chief Medical Officer Dec. 22, 2021 A 22,675 0 0 $0
Mark S Shearman EVP, Chief Scientific Officer Dec. 22, 2021 A 41,785 0 0 $0
Judith R Abrams Chief Medical Officer Oct. 28, 2019 A 25,000 0 0 $0
Vickesh Myer Chief Technology Officer March 18, 2019 M 0 0 0 $0
Gerald Frank Cox Chief Medical Officer Feb. 7, 2018 A 4,000 0 0 $0
Elliott M. Levy Director June 17, 2026 A 0 0 $0
David Scadden Director June 17, 2026 A 0 0 $0
Bernadette Connaughton Director June 17, 2026 A 0 0 $0
Jessica Hopfield Director June 17, 2026 A 22,700 0 0 $0
Andrew Hirsch Director June 17, 2026 A 0 0 $0
Emma Reeve Director Sept. 3, 2021 A 0 0 $0
Meeta Chatterjee Director June 3, 2021 A 0 0 $0
Boris Nikolic Director June 15, 2018 A 35,000 0 0 $0
Douglas G. Cole Director Aug. 17, 2017 J 3,171 0 0 $0
Kevin Bitterman Director June 15, 2017 A 2,797,144 0 0 $0
Alexis Borisy Director June 15, 2017 A 0 0 0 $0
John Mendlein Director June 15, 2017 A 0 0 $0
Kevin P Starr 10% owner Sept. 6, 2016 S 0 0 0 $0
bng0, LLC 10% owner Feb. 8, 2016 C 2,649,572 0 0 $0
Patrick Thomas Ellinor II Aug. 6, 2026 A 0 0 $0
Amy Parison Aug. 3, 2026 S 14,292 0 2 $-3,002
Akshay Vaishnaw June 3, 2021 A 0 0 $0
Charles Albright Dec. 15, 2020 M 24,907 0 0 $0
Alexandra Glucksmann March 15, 2017 M 117,788 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Polaris Venture Partners VI, L.P. (“PVP VI”), Polaris Venture Founders’ Fund VI, L.P. (“PVPFF VI”), Polaris Venture Management Co. VI, L.L.C. (“PVM VI”), Jonathan A. Flint (“Flint”), Terrance G. McGuire (“McGuire”), Brian Chee (“Chee”), David Barrett (“Barrett”), Amir Nashat (“Nashat”), Bryce Youngren (“Youngren”) ×4 filings Sept. 18, 2017 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 28 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
GNOM · Global X Funds 0.34% 54,725 NS May 31, 2026 N-PORT
BIB · ProShares Trust 0.02% 3,611 NS May 31, 2026 N-PORT
TMFX · RBB Fund, Inc. 0.02% 1,527 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.01% 42,610 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.01% 4,633 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.01% 476,309 NS May 31, 2026 N-PORT
UWM · ProShares Trust 0.01% 3,622 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 32,379 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 3,660 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 92 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,922 NS May 31, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 96,350 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
IWV · iShares Trust Aug. 18, 2026 Daily
IWN · iShares Trust Aug. 17, 2026 Daily
IWO · iShares Trust Aug. 18, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IBB · iShares Trust Aug. 18, 2026 Daily
IWC · iShares Trust Aug. 18, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust July 13, 2026 Daily
VHT · VANGUARD WORLD FUND July 20, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … July 20, 2026 Daily
QQQS · Invesco Exchange-Traded Fund Trust … July 20, 2026 Daily