EDIT — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| TCG Crossover Management, LLC | $36,000,000 | 11,111,111 | 8.86% | Shares |
| BlackRock, Inc. | $34,311,568 | 10,589,990 | 8.44% | Shares |
| RA CAPITAL MANAGEMENT, L.P. | $28,800,360 | 8,889,000 | 7.09% | Shares |
| Commodore Capital LP | $28,800,360 | 8,889,000 | 7.09% | Shares |
| ADAR1 Capital Management, LLC | $28,800,360 | 8,889,000 | 7.09% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $19,897,929 | 6,141,336 | 4.90% | Shares |
| Paradigm Biocapital Advisors LP | $18,100,665 | 5,586,625 | 4.45% | Shares |
| VANGUARD GROUP INC | $16,826,539 | 8,208,068 | 4.14% | Shares |
| Opaleye Management Inc. | $12,512,653 | 3,861,930 | 3.08% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $11,658,618 | 3,598,339 | 2.87% | Shares |
| Woodline Partners LP | $11,519,810 | 3,555,497 | 2.84% | Shares |
| Vivo Capital, LLC | $11,519,010 | 3,555,250 | 2.83% | Shares |
| GordonMD Global Investments LP | $10,131,480 | 3,127,000 | 2.49% | Shares |
| GOLDMAN SACHS GROUP INC | $8,469,476 | 2,614,036 | 2.08% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $8,325,643 | 2,569,072 | 2.05% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $7,999,298 | 2,468,919 | 1.97% | Shares |
| Logos Global Management LP | $7,199,280 | 2,222,000 | 1.77% | Shares |
| STATE STREET CORP | $7,101,442 | 2,191,803 | 1.75% | Shares |
| MARSHALL WACE, LLP | $6,600,808 | 2,037,287 | 1.62% | Shares |
| D. E. Shaw & Co., Inc. | $6,159,246 | 1,901,002 | 1.52% | Shares |
| JPMORGAN CHASE & CO | $5,959,980 | 1,862,494 | 1.47% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $5,094,065 | 1,572,242 | 1.25% | Shares |
| TWO SIGMA INVESTMENTS, LP | $4,318,842 | 1,332,976 | 1.06% | Shares |
| Seven Fleet Capital Management LP | $4,310,820 | 1,330,500 | 1.06% | Shares |
| RAYMOND JAMES FINANCIAL INC | $4,273,389 | 1,318,947 | 1.05% | Shares |
| KENNEDY CAPITAL MANAGEMENT LLC | $3,344,111 | 1,032,133 | 0.82% | Shares |
| MACKENZIE FINANCIAL CORP | $2,844,856 | 878,042 | 0.70% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2,812,424 | 868,032 | 0.69% | Shares |
| Nantahala Capital Management, LLC | $2,762,748 | 852,700 | 0.68% | Shares |
| NORTHERN TRUST CORP | $2,655,806 | 819,693 | 0.65% | Shares |
| TWO SIGMA ADVISERS, LP | $2,509,405 | 1,224,100 | 0.62% | Shares |
| UBS Group AG | $2,432,472 | 750,763 | 0.60% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $2,407,158 | 742,950 | 0.59% | Shares |
| Nuveen, LLC | $1,688,730 | 521,213 | 0.42% | Shares |
| MILLENNIUM MANAGEMENT LLC | $1,616,750 | 498,997 | 0.40% | Shares |
| Susquehanna Portfolio Strategies, LLC | $1,545,801 | 477,099 | 0.38% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,521,180 | 469,500 | 0.37% | Call option |
| Eversept Partners, LP | $1,486,541 | 458,809 | 0.37% | Shares |
| Casdin Capital, LLC | $1,441,800 | 445,000 | 0.35% | Shares |
| PEAK6 LLC | $1,346,029 | 415,441 | 0.33% | Shares |
| DIADEMA PARTNERS LP | $1,296,000 | 400,000 | 0.32% | Call option |
| MORGAN STANLEY | $1,108,616 | 342,165 | 0.27% | Shares |
| BIT Capital GmbH | $1,056,240 | 326,000 | 0.26% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $1,002,440 | 309,395 | 0.25% | Shares |
| Cubist Systematic Strategies, LLC | $994,094 | 286,482 | 0.24% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $878,642 | 271,186 | 0.22% | Shares |
| Bank of New York Mellon Corp | $850,907 | 262,625 | 0.21% | Shares |
| BANK OF AMERICA CORP /DE/ | $751,119 | 231,827 | 0.18% | Shares |
| LPL Financial LLC | $748,813 | 231,115 | 0.18% | Shares |
| Erste Asset Management GmbH | $736,000 | 230,000 | 0.18% | Shares |
| IEQ CAPITAL, LLC | $705,623 | 217,785 | 0.17% | Shares |
| CITADEL ADVISORS LLC | $689,345 | 212,761 | 0.17% | Shares |
| Invesco Ltd. | $686,492 | 211,880 | 0.17% | Shares |
| Walleye Capital LLC | $595,703 | 183,859 | 0.15% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $558,900 | 172,500 | 0.14% | Put option |
| CITADEL ADVISORS LLC | $557,604 | 172,100 | 0.14% | Put option |
| DAFNA Capital Management LLC | $552,323 | 170,470 | 0.14% | Shares |
| Mariner, LLC | $548,500 | 169,291 | 0.13% | Shares |
| Green Alpha Advisors, LLC | $505,589 | 156,046 | 0.12% | Shares |
| PEAK6 LLC | $497,340 | 153,500 | 0.12% | Call option |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $490,555 | 151,406 | 0.12% | Shares |
| Russell Investments Group, Ltd. | $485,558 | 149,864 | 0.12% | Shares |
| BARCLAYS PLC | $483,615 | 149,264 | 0.12% | Shares |
| ALLIANCEBERNSTEIN L.P. | $464,187 | 187,930 | 0.11% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $445,030 | 137,355 | 0.11% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $408,240 | 126,000 | 0.10% | Shares |
| Point72 Asset Management, L.P. | $405,758 | 125,234 | 0.10% | Shares |
| WELLS FARGO & COMPANY/MN | $391,240 | 120,753 | 0.10% | Shares |
| RHUMBLINE ADVISERS | $380,421 | 117,417 | 0.09% | Shares |
| JANE STREET GROUP, LLC | $374,473 | 115,578 | 0.09% | Shares |
| FMR LLC | $360,281 | 111,198 | 0.09% | Shares |
| DEUTSCHE BANK AG\ | $321,942 | 99,365 | 0.08% | Shares |
| HSBC HOLDINGS PLC | $314,481 | 97,062 | 0.08% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $300,818 | 92,845 | 0.07% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $300,226 | 92,094 | 0.07% | Shares |
| AMERICAN CENTURY COMPANIES INC | $300,011 | 92,596 | 0.07% | Shares |
| CWM, LLC | $259,352 | 105,001 | 0.06% | Shares |
| STIFEL FINANCIAL CORP | $242,293 | 74,782 | 0.06% | Shares |
| CITADEL ADVISORS LLC | $229,392 | 70,800 | 0.06% | Call option |
| OSAIC HOLDINGS, INC. | $227,198 | 70,124 | 0.06% | Shares |
| SEI INVESTMENTS CO | $221,188 | 68,268 | 0.05% | Shares |
| Joel Isaacson & Co., LLC | $220,787 | 68,144 | 0.05% | Shares |
| JANE STREET GROUP, LLC | $218,376 | 67,400 | 0.05% | Put option |
| SIMPLEX TRADING, LLC | $207,275 | 63,974 | 0.05% | Shares |
| CITIGROUP INC | $200,763 | 61,964 | 0.05% | Shares |
| MetLife Investment Management, LLC | $182,140 | 56,216 | 0.04% | Shares |
| Cerity Partners LLC | $181,867 | 56,132 | 0.04% | Shares |
| MML INVESTORS SERVICES, LLC | $168,765 | 52,088 | 0.04% | Shares |
| GROUP ONE TRADING LLC | $163,131 | 50,349 | 0.04% | Shares |
| Creative Planning | $147,653 | 45,572 | 0.04% | Shares |
| China Universal Asset Management Co., Ltd. | $143,934 | 44,424 | 0.04% | Shares |
| WINTON GROUP Ltd | $141,588 | 43,700 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $138,876 | 42,863 | 0.03% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $137,376 | 42,400 | 0.03% | Shares |
| Graham Capital Management, L.P. | $134,369 | 41,472 | 0.03% | Shares |
| Quinn Opportunity Partners LLC | $129,600 | 40,000 | 0.03% | Shares |
| Vanguard Personalized Indexing Management, LLC | $124,108 | 38,305 | 0.03% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $121,967 | 37,644 | 0.03% | Shares |
| Balyasny Asset Management L.P. | $121,947 | 37,638 | 0.03% | Shares |
| AXQ CAPITAL, LP | $118,104 | 36,452 | 0.03% | Shares |
| SCS Capital Management LLC | $113,400 | 35,000 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $109,749 | 33,873 | 0.03% | Shares |
| Thrive Wealth Management, LLC | $108,540 | 33,500 | 0.03% | Shares |
| TWO SIGMA SECURITIES, LLC | $107,367 | 33,138 | 0.03% | Shares |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $102,359 | 31,207 | 0.03% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $98,159 | 30,296 | 0.02% | Shares |
| HORIZON KINETICS ASSET MANAGEMENT LLC | $89,683 | 27,680 | 0.02% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $88,339 | 27,265 | 0.02% | Shares |
| Focus Partners Wealth | $88,336 | 27,264 | 0.02% | Shares |
| EntryPoint Capital, LLC | $87,299 | 26,944 | 0.02% | Shares |
| Prime Capital Investment Advisors, LLC | $85,766 | 26,471 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $85,536 | 26,400 | 0.02% | Call option |
| Vise Technologies, Inc. | $83,573 | 25,794 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $83,148 | 25,663 | 0.02% | Shares |
| DLK Investment Management, LLC | $82,668 | 17,702 | 0.02% | Shares |
| Corient Private Wealth LP | $79,854 | 24,646 | 0.02% | Shares |
| XTX Topco Ltd | $77,656 | 23,968 | 0.02% | Shares |
| COMMONWEALTH EQUITY SERVICES, LLC | $74,370 | 22,954 | 0.02% | Shares |
| Rockefeller Capital Management L.P. | $72,787 | 22,465 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $71,231 | 21,985 | 0.02% | Shares |
| State of Wyoming | $69,790 | 21,540 | 0.02% | Shares |
| HighTower Advisors, LLC | $69,718 | 21,518 | 0.02% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $66,537 | 20,536 | 0.02% | Shares |
| INDEPENDENT FINANCIAL GROUP, LLC | $66,128 | 20,410 | 0.02% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $61,884 | 19,100 | 0.02% | Shares |
| PRUDENTIAL FINANCIAL INC | $60,718 | 18,740 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $59,000 | 18,103 | 0.01% | Shares |
| ProShare Advisors LLC | $58,765 | 18,137 | 0.01% | Shares |
| BRIGHTON JONES LLC | $57,515 | 17,751 | 0.01% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $57,160 | 17,642 | 0.01% | Shares |
| Cetera Investment Advisers | $52,336 | 16,153 | 0.01% | Shares |
| StoneX Group Inc. | $51,085 | 16,213 | 0.01% | Shares |
| STRATEGIC ADVISORY PARTNERS, LLC | $48,691 | 15,028 | 0.01% | Shares |
| Abel Hall, LLC | $47,638 | 14,703 | 0.01% | Shares |
| Persistent Asset Partners Ltd | $47,303 | 1,023 | 0.01% | Call option |
| Callan Family Office, LLC | $46,860 | 14,463 | 0.01% | Shares |
| Brevan Howard Capital Management LP | $46,523 | 14,359 | 0.01% | Shares |
| Keystone Financial Group | $45,522 | 14,050 | 0.01% | Shares |
| Aries Wealth Management | $40,500 | 12,500 | 0.01% | Shares |
| Pallas Capital Advisors LLC | $37,944 | 11,711 | 0.01% | Shares |
| Merit Financial Group, LLC | $37,474 | 11,566 | 0.01% | Shares |
| Gibbs Wealth Management | $35,769 | 10,308 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $35,731 | 11,028 | 0.01% | Shares |
| Point72 (DIFC) Ltd | $34,276 | 9,878 | 0.01% | Shares |
| Valeo Financial Advisors, LLC | $32,536 | 10,042 | 0.01% | Shares |
| Kera Capital Partners, Inc. | $32,462 | 10,019 | 0.01% | Shares |
| Raiffeisen Bank International AG | $32,400 | 10,000 | 0.01% | Call option |
| Legal & General Group Plc | $31,454 | 9,708 | 0.01% | Shares |
| PNC Financial Services Group, Inc. | $29,166 | 9,002 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $26,714 | 8,245 | 0.01% | Shares |
| CIBC Private Wealth Group LLC | $25,331 | 7,300 | 0.01% | Shares |
| Arax Advisory Partners | $23,863 | 7,365 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $22,236 | 6,863 | 0.01% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $14,237 | 4,394 | 0.00% | Shares |
| Allworth Financial LP | $13,542 | 4,180 | 0.00% | Shares |
| Point72 Europe (London) LLP | $13,300 | 3,833 | 0.00% | Shares |
| Dunhill Financial, LLC | $12,960 | 4,000 | 0.00% | Shares |
| Activest Wealth Management | $12,960 | 4,000 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $10,744 | 3,316 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $9,827 | 3,033 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $8,236 | 2,542 | 0.00% | Shares |
| Owl Creek Wealth Partners LLC | $7,728 | 2,385 | 0.00% | Shares |
| Atlantic Union Bankshares Corp | $7,459 | 2,302 | 0.00% | Shares |
| Federation des caisses Desjardins du Quebec | $7,452 | 2,300 | 0.00% | Shares |
| Essential Partners LLC | $5,262 | 1,624 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $5,241 | 1,839 | 0.00% | Shares |
| Leonteq Securities AG | $4,565 | 1,409 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $4,465 | 1,378 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $4,348 | 1,342 | 0.00% | Shares |
| SIGNATUREFD, LLC | $4,212 | 1,300 | 0.00% | Shares |
| NewEdge Advisors, LLC | $4,196 | 1,295 | 0.00% | Shares |
| GAMMA Investing LLC | $4,154 | 1,282 | 0.00% | Shares |
| Twin Lakes Capital Management, LLC | $4,050 | 1,250 | 0.00% | Shares |
| FEDERATED HERMES, INC. | $3,726 | 1,150 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $3,364 | 1,039,001 | 0.00% | Shares |
| Wilmington Savings Fund Society, FSB | $3,240 | 1,000 | 0.00% | Shares |
| Stone House Investment Management, LLC | $3,240 | 1,000 | 0.00% | Shares |
| Costello Asset Management, INC | $3,240 | 1,000 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $3,020 | 932 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $2,961 | 914 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $2,686 | 829 | 0.00% | Shares |
| Tradewinds Capital Management, LLC | $2,268 | 700 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $2,108 | 653 | 0.00% | Shares |
| Physician Wealth Advisors, Inc. | $2,103 | 649 | 0.00% | Shares |
| Fortitude Family Office, LLC | $1,944 | 600 | 0.00% | Shares |
| MassMutual Private Wealth & Trust, FSB | $1,717 | 530 | 0.00% | Shares |
| Sterling Capital Management LLC | $1,691 | 522 | 0.00% | Shares |
| AllSquare Wealth Management LLC | $1,648 | 475 | 0.00% | Shares |
| IFP Advisors, Inc | $1,639 | 506 | 0.00% | Shares |
| TRUST CO OF TOLEDO NA /OH/ | $1,620 | 500 | 0.00% | Shares |
| GILL CAPITAL PARTNERS, LLC | $1,377 | 425 | 0.00% | Shares |
| True Wealth Design, LLC | $1,335 | 412 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $1,331 | 410 | 0.00% | Shares |
| HOLLENCREST CAPITAL MANAGEMENT | $1,296 | 400 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $1,190 | 367,147 | 0.00% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1,186 | 480 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $1,167 | 360 | 0.00% | Shares |
| Rialto Wealth Management, LLC | $1,053 | 325 | 0.00% | Shares |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $1,008 | 311 | 0.00% | Shares |
| Larson Financial Group LLC | $936 | 289 | 0.00% | Shares |
| Optiver Holding B.V. | $839 | 259 | 0.00% | Shares |
| HM PAYSON & CO | $681 | 210 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $656 | 200 | 0.00% | Shares |
| Cambridge Investment Research Advisors, Inc. | $524 | 161,878 | 0.00% | Shares |
| ISLAY CAPITAL MANAGEMENT, LLC | $486 | 150 | 0.00% | Shares |
| Clearstead Advisors, LLC | $399 | 123 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $387 | 119,429 | 0.00% | Shares |
| Quarry LP | $363 | 112 | 0.00% | Shares |
| Plante Moran Financial Advisors, LLC | $324 | 100 | 0.00% | Shares |
| Pinnacle Wealth Planning Services, Inc. | $324 | 100 | 0.00% | Shares |
| Smartleaf Asset Management LLC | $320 | 100 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $306 | 124 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $305 | 94 | 0.00% | Shares |
| SHP Wealth Management | $292 | 90 | 0.00% | Shares |
| Versant Capital Management, Inc | $257 | 100 | 0.00% | Shares |
| CANADA LIFE ASSURANCE Co | $255 | 78,602 | 0.00% | Shares |
| Key Financial Inc | $243 | 75 | 0.00% | Shares |
| Truvestments Capital LLC | $198 | 61 | 0.00% | Shares |
| Parallel Advisors, LLC | $194 | 60 | 0.00% | Shares |
| MCF Advisors LLC | $175 | 54 | 0.00% | Shares |
| DT Investment Partners, LLC | $175 | 54 | 0.00% | Shares |
| Gen-Wealth Partners Inc | $172 | 53 | 0.00% | Shares |
| Center for Financial Planning, Inc. | $162 | 50 | 0.00% | Shares |
| EVOLUTION WEALTH MANAGEMENT INC. | $162 | 50 | 0.00% | Shares |
| North Star Investment Management Corp. | $123 | 38 | 0.00% | Shares |
| COMERICA BANK | $111 | 54 | 0.00% | Shares |
| Colonial Trust Advisors | $97 | 30 | 0.00% | Shares |
| Hilton Head Capital Partners, LLC | $87 | 27 | 0.00% | Shares |
| CoreCap Advisors, LLC | $49 | 15 | 0.00% | Shares |
| Abich Financial Wealth Management LLC | $42 | 12 | 0.00% | Shares |
| Financial Perspectives, Inc | $19 | 6 | 0.00% | Shares |
| JPL Wealth Management, LLC | $13 | 4 | 0.00% | Shares |
| Forum Finance Group S.A. | $7 | 2,500 | 0.00% | Shares |
| Sandy Spring Bank | $3 | 2 | 0.00% | Shares |
| Covestor Ltd | $0 | 108 | 0.00% | Shares |
| HANTZ FINANCIAL SERVICES, INC. | $0 | 100 | 0.00% | Shares |