ENTA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $12.96
Market Cap (MRQ) $377M
P/E (TTM) -5.4
EPS (TTM) $-2.42
Revenue (TTM) $65M
ROE (TTM) -70.1%
52W Range $10–$17

ENTA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$65M
2016-09-30 → 2025-09-30
EPS$-3.84
2016-09-30 → 2025-09-30
Free Cash Flow$-32M
2017-09-30 → 2025-09-30
Net margin-96.9%
2017-09-30 → 2025-09-30
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend ENTA 5Y avg Peer Median Verdict
P/E (TTM) -5.45Y avg ≈-6.0 ≈-6.0 · ·
P/S (TTM) 5.85Y avg ≈6.9 ≈6.9 51.3 Undervalued
P/B (MRQ) 3.75Y avg ≈2.6 ≈2.6 2.4 Overvalued
Price / FCF (TTM) -10.25Y avg ≈-8.2 ≈-8.2 · ·
Price / Cash Flow (TTM) -10.75Y avg ≈-9.5 ≈-9.5 · ·
Price / Tangible Book 4.35Y avg ≈2.6 ≈2.6 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 14.9%
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 10, 2026 $-0.67 $-0.52 -28.8%
March 31, 2026 $-0.45 $-0.50 9.6%
Dec. 31, 2025 $-0.42 $-0.82 49.0%
Sept. 30, 2025 $-0.87 $-1.04 16.5%
June 30, 2025 $-0.85 $-1.30 34.7%
March 31, 2025 $-1.06 $-1.16 8.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $65M$68M$79M$86M$97M$122M$205M$207M$103M$88M$161M$48M
R&D Expense $107M$131M$164M$165M$174M$137M$142M$95M$57M$40M$23M$19M
SG&A Expense $44M$58M$53M$45M$33M$27M$26M$23M$21M$17M$14M$10M
Operating Expenses $151M$189M$216M$210M$207M$164M$168M$118M$78M$57M$37M$29M
Operating Income $-85M$-122M$-137M$-124M$-110M$-42M$37M$88M$25M$31M$124M$19M
Interest Expense ··$5M$0$0···$40.0K$45.0K$8.0K$18.0K
Interest Income ········$3M$2M$968.0K$467.0K
Other Non-op $2M$4M$6M$2M$2M$7M$9M$5M$2M$2M··
Pretax Income $-84M$-118M$-131M$-122M$-108M$-35M$46M$93M$27M$33M$125M$19M
Income Tax $-2M$-2M$3M$-433.0K$-29M$1M$-826.0K$21M$9M$11M$46M$-15M
Net Income $-82M$-116M$-134M$-122M$-79M$-36M$46M$72M$18M$22M$79M$34M
EPS (Basic) $-3.84$-5.48$-6.38$-5.91$-3.92$-1.81$2.37$3.74$0.93$1.14$4.23$1.88
EPS (Diluted) $-3.84$-5.48$-6.38$-5.91$-3.92$-1.81$2.21$3.48$0.91$1.13$4.09$1.80
Shares (Basic) 21,33621,15720,96920,60320,17119,94019,584,00019,255,00019,066,00018,929,00018,673,00018,355
Shares (Diluted) 21,33621,15720,96920,60320,17119,94020,968,00020,650,00019,407,00019,224,00019,295,00019,185
EBITDA $-85M$-122M$-137M$-124M$-110M$-42M$37M$88M$25M·$124M$19M
Balance Sheet 24
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $32M$37M$85M$44M$57M$87M$51M$64M$66M$17M$22M$31M
Short-term Investments ········$158M$194M$123M$60M
Receivables $7M$7M$9M$20M$24M$23M$51M$67M$11M$13M$15M$2M
Prepaid Expense $9M$12M$13M$13M$14M$14M$15M$4M$4M$9M$8M$2M
Current Assets $204M$300M$423M$312M$319M$437M$402M$380M$238M$232M$171M$108M
PP&E (Net) $35M$33M$12M$6M$6M$9M$11M$8M$8M$8M$6M$2M
PP&E (Gross) $59M$58M$36M$28M$25M$24M$23M$17M$15M$13M$10M$6M
Accum. Depreciation $24M$25M$24M$22M$19M$16M$12M$9M$7M$5M$4M$4M
Other Non-current Assets $92.0K$94.0K$803.0K$696.0K$92.0K$92.0K$92.0K$92.0K····
Total Assets $281M$377M$462M$375M$439M$486M$490M$414M$327M$281M$246M$155M
Accounts Payable $2M$8M$4M$6M$10M$6M$7M$5M$4M$3M$2M$2M
Accrued Liabilities $13M$14M$18M$21M$22M$14M$16M$10M$8M$5M$4M$3M
Current Liabilities $49M$58M$63M$30M$36M$24M$23M$16M$21M$8M$7M$5M
Capital Leases $55M$54M$21M$22M$1M$4M$200.0K$293.0K$379.0K$458.0K$529.0K·
Other Non-current Liabilities $260.0K$231.0K$663.0K$454.0K$558.0K$1M$3M$3M$2M$2M$2M$229.0K
Total Liabilities $216M$248M$246M$54M$39M$31M$27M$21M$25M$11M$10M$7M
Common Stock $214.0K$212.0K$211.0K$208.0K$202.0K$201.0K$197.0K$194.0K$191.0K$190.0K$187.0K$188.0K
Paid-in Capital ···········$222M
Retained Earnings $-405M$-323M$-207M$-73M$49M$128M$164M$117M$45M$28M$6M$-73M
Treasury Stock ···········$2.0K
AOCI $-339.0K$302.0K$-1M$-4M$-382.0K$844.0K$146.0K$-398.0K$-112.0K$19.0K$33.0K$-100.0K
Stockholders' Equity $65M$129M$217M$321M$399M$456M$462M$394M$302M$270M$236M$149M
Liabilities + Equity $281M$377M$462M$375M$439M$486M$490M$414M$327M$281M$246M$155M
Shares Outstanding 21,387,00021,387,00021,059,00020,791,00020,238,00020,077,00019,703,00019,395,00019,120,00019,036,00018,716,83418,594,574
Cash Flow 11
Metric Trend 202520242023202220212020201920182017201620152014
D&A $5M$2M$2M$3M$3M$4M$3M$3M$2M$2M$639.0K$352.0K
Stock-based Comp $19M$27M$28M$27M$21M$20M$19M$16M$13M$9M$6M$3M
Deferred Tax ·····$-18M·····$-15M
Operating Cash Flow $-19M$-79M$-103M$-85M$-70M$7M$71M$29M$53M$36M$77M$20M
CapEx $13M$18M$9M$2M$750.0K$1M$5M$3M$3M$5M$2M$1M
Investing Cash Flow $40M$58M$-54M$55M$37M$20M$-87M$-35M$-5M$-44M··
Financing Cash Flow $-27M$-28M$198M$20M$3M$9M$3M$4M$1M$3M··
Net Change in Cash $-6M$-48M$41M$-10M$-30M$36M$-13M$-2M$49M$-5M$-9M$22M
Taxes Paid ·········$13M$40M$148.0K
Free Cash Flow $-32M$-97M$-112M$-87M$-71M$6M$66M$26M$50M·$74M$19M
Levered FCF ··$-117M·····$50M·$74M$19M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -130.7%-179.9%-173.2%-143.7%-112.9%-34.0%17.9%42.8%23.9%·77.2%39.8%
Net Margin -125.4%-171.6%-168.9%-141.3%-81.4%-29.5%22.6%34.8%17.2%·49.1%72.1%
Pretax Margin -127.9%-174.2%-165.4%-141.8%-110.8%-28.6%22.2%45.1%26.2%·78.0%40.4%
EBITDA Margin -130.7%-179.9%-173.2%-143.7%-112.9%-34.0%17.9%42.8%23.9%·77.2%39.8%
ROA -24.9%-27.7%-31.9%-29.9%-17.1%-7.4%10.3%19.4%5.8%·39.4%25.3%
ROE -103.5%-83.6%-58.9%-36.9%-19.3%-7.7%10.2%19.1%6.2%·41.0%26.6%
ROIC -129.3%-93.1%-64.7%-38.4%-20.1%-9.4%8.1%17.3%5.4%·33.1%22.8%
Liquidity & Solvency 3
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 4.25.26.710.58.818.117.823.711.3·25.522.8
Quick Ratio 0.80.81.52.22.24.64.58.211.2·23.919.5
Interest Coverage ··-26.7·····615.4·15518.51054.7
Efficiency 2
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.20.20.20.20.30.50.60.3·0.80.4
Receivables Turnover 9.78.95.53.94.13.33.55.38.8·18.937.7
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $3.03$6.08$10.29$15.46$19.74$22.69$23.47$20.30$15.78·$12.62$7.99
Revenue / Share $3061.68$3196.81$3777.19$4181.92$4.81$6.14$9.79$10.01$5.30·$8.34$2.49
Cash Flow / Share $-903.26$-3722.83$-4919.36$-4115.03$-3.47$0.36$3.41$1.42$2.71·$3.97$1.05
Cash / Share $1.51$1.76$4.05$2.12$2.83$4.34$2.60$3.29$3.43·$1.16$1.65
EPS (TTM) $-3.84$-5.48$-6.38$-5.91$-3.92$-1.81$2.21$3.48$0.91$1.13$4.09$1.80
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY -3.4%-14.6%-8.1%-11.2%-20.7%·······
Revenue CAGR 3Y -8.8%-11.3%-13.5%·········
Revenue CAGR 5Y -11.8%···········
Valuation (TTM) 10
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $65M$68M$79M$86M$97M$122M$205M$207M$103M$88M$161M$48M
Net Income TTM $-82M$-116M$-134M$-122M$-79M$-36M$46M$72M$18M$22M$79M$34M
Market Cap $256M$220M$235M$1.08B$1.15B$919M$1.18B$1.66B$895M·$676M$736M
P/E -3.1-1.9-1.8-8.8-14.5-25.327.224.651.423.58.822.0
P/S 3.93.23.012.511.87.55.88.08.7·4.215.4
P/B 4.01.71.13.42.92.02.64.23.0·2.94.9
P / Tangible Book 4.01.71.13.42.92.0······
P / Cash Flow -13.3-2.8-2.3-12.7-16.4129.716.656.717.0·8.836.5
P / FCF -8.0-2.3-2.1-12.4-16.3162.917.963.217.8·9.138.4
Earnings Yield -32.1%-52.9%-57.1%-11.4%-6.9%-4.0%3.7%4.1%1.9%4.2%11.3%4.5%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-09-302024-09-302023-09-302022-09-302021-09-30
Revenue $65M $68M $79M $86M $97M
Operating Margin % -130.7% -179.9% -173.2% -143.7% -112.9%
Net Income $-82M $-116M $-134M $-122M $-79M
Diluted EPS $-3.84 $-5.48 $-6.38 $-5.91 $-3.92

Institutional owners (13F) 133 filers · $373.6M total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 133
Value held $373.6M
New positions 14
Exited positions 19
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
14 (-14 vs prior Q) 19 (0 vs prior Q) 48 (+1 vs prior Q) 37 (+3 vs prior Q) -113K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
JANUS HENDERSON GROUP PLC $47,716,934 3,784,055 12.77% Shares
BlackRock, Inc. $47,304,051 3,244,448 12.66% Shares
VANGUARD GROUP INC $36,299,291 2,301,794 9.72% Shares
FARALLON CAPITAL MANAGEMENT, L.L.C. $35,257,385 2,418,202 9.44% Shares
Deep Track Capital, LP $21,055,955 1,444,167 5.64% Shares
ADAR1 Capital Management, LLC $19,602,956 1,344,510 5.25% Shares
VANGUARD CAPITAL MANAGEMENT LLC $17,667,592 1,211,769 4.73% Shares
Spruce Street Capital LP $15,873,698 1,088,731 4.25% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $14,747,583 1,011,494 3.95% Shares
GEODE CAPITAL MANAGEMENT, LLC $11,325,842 776,634 3.03% Shares
MILLENNIUM MANAGEMENT LLC $9,389,039 643,967 2.51% Shares
STATE STREET CORP $8,399,786 576,117 2.25% Shares
RENAISSANCE TECHNOLOGIES LLC $8,129,808 557,600 2.18% Shares
Hillsdale Investment Management Inc. $6,823,440 468,000 1.83% Shares
GOLDMAN SACHS GROUP INC $6,774,583 464,649 1.81% Shares
MORGAN STANLEY $4,603,338 315,729 1.23% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4,390,782 301,151 1.18% Shares
DIMENSIONAL FUND ADVISORS LP $4,121,427 282,682 1.10% Shares
NORTHERN TRUST CORP $3,786,368 259,696 1.01% Shares
SummitTX Capital, L.P. $3,757,295 257,702 1.01% Shares
AQR CAPITAL MANAGEMENT LLC $3,745,165 256,870 1.00% Shares
VANGUARD FIDUCIARY TRUST CO $2,706,310 185,618 0.72% Shares
TWO SIGMA ADVISERS, LP $2,259,841 143,300 0.60% Shares
Connor, Clark & Lunn Investment Management Ltd. $2,230,857 153,008 0.60% Shares
Rockefeller Capital Management L.P. $2,194,960 150,546 0.59% Shares
MARSHALL WACE, LLP $1,924,487 131,995 0.52% Shares
Opaleye Management Inc. $1,822,500 125,000 0.49% Shares
JPMORGAN CHASE & CO $1,404,045 96,764 0.38% Shares
Russell Investments Group, Ltd. $1,227,255 84,231 0.33% Shares
WELLINGTON MANAGEMENT GROUP LLP $1,190,209 81,633 0.32% Shares
Qube Research & Technologies Ltd $1,181,053 81,005 0.32% Shares
Bank of New York Mellon Corp $1,119,105 76,756 0.30% Shares
XTX Topco Ltd $1,100,323 75,468 0.29% Shares
TWO SIGMA INVESTMENTS, LP $1,037,542 71,162 0.28% Shares
Campbell & CO Investment Adviser LLC $1,031,739 70,764 0.28% Shares
Trexquant Investment LP $1,014,958 69,613 0.27% Shares
MACKENZIE FINANCIAL CORP $982,211 67,367 0.26% Shares
SEI INVESTMENTS CO $972,264 66,685 0.26% Shares
UBS Group AG $937,771 64,319 0.25% Shares
Invesco Ltd. $867,948 59,530 0.23% Shares
Nuveen, LLC $832,970 57,131 0.22% Shares
CITADEL ADVISORS LLC $741,305 50,844 0.20% Shares
FRANKLIN RESOURCES INC $707,393 48,518 0.19% Shares
Quantinno Capital Management LP $657,689 45,109 0.18% Shares
Cubist Systematic Strategies, LLC $598,297 49,983 0.16% Shares
STATE OF WISCONSIN INVESTMENT BOARD $596,439 40,908 0.16% Shares
PRUDENTIAL FINANCIAL INC $581,232 39,865 0.16% Shares
IEQ CAPITAL, LLC $561,447 38,508 0.15% Shares
PANAGORA ASSET MANAGEMENT INC $507,224 34,789 0.14% Shares
RHUMBLINE ADVISERS $504,034 34,571 0.13% Shares

Show all 133 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Jay R. Luly, Ph.D. ×4 filings Feb. 14, 2025 7.70% Amendment · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 26 insiders · 12 officers · 14 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Jay R. Luly, Ph.D. President and CEO Feb. 12, 2026 F 871,871 0 1 $-67,493
Scott T. Rottinghaus Chief Medical Officer Aug. 8, 2026 F 23,787 0 1 $-11,356
Brendan Luu Chief Business Officer Feb. 12, 2026 F 41,634 0 1 $-19,837
Tara Lynn Kieffer Chief Product Strategy Officer Feb. 12, 2026 F 33,925 0 1 $-29,968
Matthew Paul Kowalsky Chief Legal Officer Feb. 12, 2026 F 3,591 0 0 $0
Yat Sun Or Chief Scientific Officer Feb. 12, 2026 F 374,854 0 1 $-34,010
Kathleen S. Capps Executive Director of Accounting, Controller (Principal Accounting Officer) Dec. 5, 2025 S 8,377 0 2 $-7,486
Harry R. Trout III Vice President, Finance (Principal Financial Officer) Dec. 5, 2025 S 16,348 0 2 $-13,018
Paul J Mellett Chief Fin. & Admin Officer Feb. 12, 2025 F 95,884 0 0 $0
Nathaniel S. Gardiner Chief Legal Officer Feb. 26, 2024 M 75,688 0 0 $0
Nathalie Adda Sr. VP & Chief Medical Officer April 4, 2022 M 34,982 0 0 $0
Tim Ocain Senior Vice President Feb. 12, 2019 F 17,547 0 0 $0
Yujiro S Hata Director March 11, 2026 A · 0 0 $0
Terry Vance Director March 11, 2026 A 5,800 0 0 $0
Kristine Peterson Director March 11, 2026 A · 0 0 $0
Lesley Russell Director March 11, 2026 A · 0 0 $0
Mark G Foletta Director March 11, 2026 A · 0 0 $0
Bruce L A Carter Director March 11, 2026 A 0 0 0 $0
George Golumbeski Director Feb. 26, 2020 A 0 0 0 $0
Stephen Buckley Jr. Director Feb. 28, 2019 A 2,000 0 0 $0
AFTING ERNST-GUENTER Director Feb. 11, 2016 A 17,287 0 0 $0
Helmut Schuhsler Director Feb. 24, 2014 S 1,572,670 0 0 $0
Marc E. Goldberg Director Dec. 6, 2013 S 547,606 0 0 $0
Gregory L. Verdine Director March 26, 2013 P 3,324 0 0 $0
David Poorvin Director March 20, 2013 A · 0 0 $0
SHIONOGI & CO LTD 10% owner March 26, 2013 C 1,599,760 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 23 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.50% 8,992 SH Oct. 2, 2026 Daily
IWC · iShares Trust 0.08% 95,810 SH Sept. 11, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.06% 80,033 SH Aug. 19, 2026 Daily
IBB · iShares Trust 0.03% 207,553 SH Sept. 11, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.03% 2,068 SH Oct. 2, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 34,293 SH Oct. 2, 2026 Daily
IWM · iShares Trust 0.01% 722,462 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.01% 129,551 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.01% 13,537 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 163,048 SH Aug. 19, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.01% 12,720 SH Aug. 19, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 14,867 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 62,270 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 2,200 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 47,704 SH Sept. 11, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 4,851 NS July 31, 2026 N-PORT
IWV · iShares Trust 0.00% 4,959 SH Sept. 3, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 3,542 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 308,121 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 877,120 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 2,291 SH Aug. 19, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 1,234 NS July 31, 2026 N-PORT
IWN · iShares Trust · 136,586 SH Sept. 11, 2026 Daily

ENTA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 12 analysts BUY
Median target $20.00 +54.3%
4 33.3% Strong Buy
7 58.3% Buy
1 8.3% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

6 analysts · 2026-10-04

Mean target $21.83 +68.5%

← Below all targets Current price $12.96
Low$19.00 Mean$21.83 High$32.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ENTA $256M -3.1 -3.4% -125.4% -103.5% ·
RZLT $501M -6.9 · · -67.8% ·
RCEL $105M -2.0 11.5% -67.8% 328.9% 82.1%
CCCC $185M -1.5 1.0% -292.1% -48.8% ·
EIKN · · · · · ·
EDIT $201M -1.1 25.4% -395.0% -688.8% ·
XFOR $364M -2.1 150.0% -1218.5% -83.2% ·
AGEN $111M · 10.4% -2.7% 1.0% ·
IRD $140M -2.5 29.1% -349.3% -302.2% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 12, 2026