KPTI Karyopharm Therapeutics Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 13, 2026
$0.80
· of 52w range
· above low
· to high
$0.7552w low
$10.9952w high
Market Cap (MRQ)
$18M
P/E (TTM)
-0.1
EPS (TTM)
$-14.40
Revenue (TTM)
$147M
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52W Range
$1–$11
Analyst Rating
BUY
Price Target
$7
P/E
-0.1
ROE
79.0%
Net Profit Margin
-153.3%
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KPTI Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$0.80
Market Cap (MRQ)
$18M
P/E (TTM)
-0.1
EPS (TTM)
$-14.40
Revenue (TTM)
$147M
ROE (TTM)
79.0%
52W Range
$1–$11
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| Feb. 26, 2025 | 1-for-15 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
Revenue$146M2016-12-31 → 2025-12-31
EPS$-17.932020-12-31 → 2025-12-31
Free Cash Flow$-75M2016-12-31 → 2025-12-31
Net margin-153.3%2016-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | KPTI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E (TTM) | -0.15Y avg ≈-17.1 | ≈-17.1 | · | · | |
| P/S (TTM) | 0.15Y avg ≈18.3 | ≈18.3 | · | · | |
| P/B (MRQ) | -0.15Y avg ≈-91.3 | ≈-91.3 | · | · | |
| Price / FCF | -0.25Y avg ≈-26.9 | ≈-26.9 | · | · | |
| Price / Cash Flow | -0.25Y avg ≈-26.9 | ≈-26.9 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | KPTI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Operating Margin (TTM) | -56.2%5Y avg ≈-74.1% | ≈-74.1% | -3881.8% | Top tier | |
| EBITDA Margin | -62.1%5Y avg ≈-74.1% | ≈-74.1% | -3881.8% | Top tier | |
| Pretax Margin (TTM) | -153.3%5Y avg ≈-89.7% | ≈-89.7% | -6642.7% | Top tier | |
| Net Profit Margin (TTM) | -153.3%5Y avg ≈-89.8% | ≈-89.8% | -4978.6% | Top tier | |
| ROA (TTM) | -207.9%5Y avg ≈-63.8% | ≈-63.8% | -78.1% | Weak | |
| ROE (TTM) | 79.0%5Y avg ≈114.0% | ≈114.0% | -107.8% | Top tier | |
| ROIC | 31.0%5Y avg ≈234.0% | ≈234.0% | 29.5% | In line |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | KPTI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 0.85Y avg ≈3.0 | ≈3.0 | 2.0 | Low liquidity | |
| Quick Ratio | 0.95Y avg ≈1.7 | ≈1.7 | 1.4 | Low liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | KPTI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | 0.57%5Y avg ≈12.4% | ≈12.4% | · | · | |
| Revenue CAGR 3Y | -2.4%5Y avg ≈-1.1% | ≈-1.1% | · | · | |
| Revenue CAGR 5Y | 6.2% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | KPTI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 1.15Y avg ≈0.7 | ≈0.7 | 0.0 | Top tier | |
| Receivables Turnover | 5.15Y avg ≈6.1 | ≈6.1 | · | · | |
| Revenue / Employee | ≈$640.6K | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-10.1%
Next Report
Nov 02, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 13, 2026 | $-2.32 | $-1.30 | -78.2% |
| March 31, 2026 | May 14, 2026 | $-1.24 | $-1.46 | 14.9% |
| Dec. 31, 2025 | $-2.22 | $-2.03 | -9.1% | |
| Sept. 30, 2025 | $-3.82 | $-3.19 | -19.6% | |
| June 30, 2025 | $-4.32 | $-4.18 | -3.3% | |
| March 31, 2025 | $-2.77 | $-4.26 | 35.0% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $146M | $145M | $146M | $157M | $210M | $108M | $41M | $30M | $2M | $154.0K | $250.0K | $229.0K | |
| R&D Expense | $126M | $143M | $139M | $149M | $161M | $151M | $122M | $161M | $107M | $87M | $98M | $60M | |
| SG&A Expense | $105M | $115M | $132M | $145M | $144M | $126M | $105M | $49M | $25M | $24M | $22M | $16M | |
| Operating Expenses | $237M | $265M | $276M | $299M | $308M | $280M | $230M | $210M | $132M | $111M | $119M | $76M | |
| Operating Income | $-91M | $-119M | $-130M | $-142M | $-98M | $-172M | $-189M | $-180M | $-131M | $-111M | $-119M | $-76M | |
| Interest Expense | · | · | $24M | $25M | $26M | $27M | $16M | $2M | · | · | · | $1.0K | |
| Interest Income | $3M | $7M | $11M | $2M | $582.0K | $3M | $5M | $4M | $2M | $1M | $897.0K | $97.0K | |
| Other Non-op | $152.0K | $28M | $-356.0K | $-83.0K | $-85.0K | $206.0K | $-50.0K | $-33.0K | $-81.0K | $10.0K | $-2.0K | $-27.0K | |
| Pretax Income | $-196M | $-76M | $-143M | $-165M | $-124M | $-196M | $-200M | $-178M | $-129M | $-109M | $-118M | $-76M | |
| Income Tax | $43.0K | $57.0K | $323.0K | $369.0K | $268.0K | $309.0K | $40.0K | $26.0K | $63.0K | $139.0K | $-118M | $-76M | |
| Net Income | $-196M | $-76M | $-143M | $-165M | $-124M | $-196M | $-200M | $-178M | $-129M | $-110M | $-118M | $-76M | |
| EPS (Basic) | $-17.93 | $-9.41 | $-18.79 | $-2.02 | $-1.65 | $-2.72 | · | · | · | · | · | · | |
| EPS (Diluted) | $-17.93 | $-14.00 | $-18.79 | $-2.02 | $-1.65 | $-2.72 | · | · | · | · | · | · | |
| Shares (Basic) | 10,935 | 8,125 | 7,616 | 81,871 | 75,218,000 | 72,044,000 | · | · | · | · | · | · | |
| Shares (Diluted) | 10,935 | 8,455 | 7,616 | 81,871 | 75,218,000 | 72,044,000 | · | · | · | · | · | · | |
| EBITDA | $-91M | $-119M | $-130M | $-142M | $-98M | $-172M | $-189M | $-180M | $-131M | $-111M | $-119M | $-76M |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $62M | $52M | $135M | $190M | $86M | $129M | $118M | $69M | $50M | $58M | $151M | |
| Short-term Investments | · | · | · | · | · | · | · | · | $77M | $80M | $117M | $55M | |
| Receivables | $26M | $31M | $27M | $47M | $22M | $13M | $8M | · | · | · | · | · | |
| Inventory | $4M | $5M | $3M | $4M | $4M | $3M | $346.0K | · | · | · | · | · | |
| Prepaid Expense | $9M | $12M | $12M | $20M | $14M | $9M | $7M | $6M | $2M | $2M | $2M | $2M | |
| Other Current Assets | · | · | · | · | $2M | · | · | · | · | · | · | · | |
| Current Assets | $103M | $156M | $234M | $350M | $276M | $277M | $279M | $335M | $148M | $132M | $178M | $208M | |
| PP&E (Net) | $104.0K | $400.0K | $606.0K | $1M | $2M | $2M | $3M | $4M | $2M | $3M | $3M | $3M | |
| PP&E (Gross) | $6M | $7M | $7M | $8M | $8M | $7M | $7M | $7M | $5M | $5M | $5M | $3M | |
| Accum. Depreciation | $6M | $7M | $7M | $7M | $6M | $5M | $4M | $3M | $3M | $2M | $1M | $494.0K | |
| Other Non-current Assets | · | · | · | · | · | · | · | · | · | · | · | $774.0K | |
| Total Assets | $108M | $164M | $240M | $358M | $305M | $313M | $295M | $341M | $180M | $180M | $215M | $220M | |
| Accounts Payable | $4M | $5M | $3M | $3M | $2M | $4M | $985.0K | $4M | $6M | $5M | $4M | $6M | |
| Accrued Liabilities | $64M | $61M | $61M | $58M | $69M | $53M | $41M | $32M | $21M | $11M | $11M | $6M | |
| Current Liabilities | $92M | $92M | $69M | $66M | $74M | $60M | $46M | $47M | $49M | $16M | $15M | $12M | |
| Capital Leases | $6M | $7M | $3M | $6M | $9M | $11M | $13M | · | · | · | · | · | |
| Other Non-current Liabilities | $11M | $2M | $978.0K | $0 | · | · | · | · | · | · | · | · | |
| Total Liabilities | $401M | $350M | $377M | $375M | $385M | $263M | $245M | $158M | $51M | $18M | $17M | $14M | |
| Long-term Debt | · | · | · | · | $169M | · | · | · | · | · | · | · | |
| Common Stock | $14.0K | $13.0K | $12.0K | $12.0K | $8.0K | $7.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | $3.0K | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | · | · | $345M | |
| Retained Earnings | $-1.76B | $-1.56B | $-1.49B | $-1.34B | $-1.18B | $-1.07B | $-873M | $-674M | $-495M | $-366M | $-257M | $-138M | |
| AOCI | $71.0K | $-356.0K | $-161.0K | $-638.0K | $191.0K | $518.0K | $-37.0K | $-244.0K | $-217.0K | $-274.0K | $-282.0K | $-29.0K | |
| Stockholders' Equity | $-293M | $-186M | $-136M | $-17M | $-80M | $51M | $50M | $183M | $129M | $162M | $198M | $207M | |
| Liabilities + Equity | $108M | $164M | $240M | $358M | $305M | $313M | $295M | $341M | $180M | $180M | $215M | $220M | |
| Shares Outstanding | 18,311,000 | 8,413,000 | 114,915,000 | 113,213,000 | 75,746,000 | 73,923,000 | 65,370,000 | 60,829,308 | 49,533,150 | 41,887,829 | 35,864,765 | 32,699,380 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | $974.0K | $735.0K | $713.0K | $717.0K | $634.0K | $323.0K | |
| Stock-based Comp | $14M | $18M | $22M | $35M | $30M | $24M | $15M | $17M | $20M | $22M | $17M | $14M | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | · | |
| Operating Cash Flow | $-75M | $-127M | $-93M | $-150M | $-107M | $-160M | $-191M | $-159M | $-74M | $-84M | $-94M | $-51M | |
| CapEx | $0 | $142.0K | $0 | $118.0K | $212.0K | $145.0K | $206.0K | $2M | $62.0K | $70.0K | $1M | $3M | |
| Investing Cash Flow | $43M | $95M | $8M | $-104M | $142M | $-54M | $78M | $-108M | $17M | $25M | · | · | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | · | $113M | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | $113M | |
| Financing Cash Flow | $30M | $42M | $1M | $194M | $74M | $172M | $124M | $316M | $76M | $51M | · | · | |
| Net Change in Cash | $-2M | $10M | $-84M | $-61M | $108M | $-42M | $12M | $49M | $19M | $-9M | $-92M | $-5M | |
| Free Cash Flow | $-75M | $-128M | $-93M | $-150M | $-107M | $-160M | $-191M | $-161M | $-74M | $-84M | $-95M | $-54M | |
| Levered FCF | · | · | $-117M | $-175M | $-133M | $-188M | $-207M | $-164M | · | · | · | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -62.1% | -82.2% | -88.7% | -90.5% | -46.8% | -159.0% | -462.8% | -593.0% | · | -71903.9% | -47630.4% | -33120.5% | |
| Net Margin | -134.2% | -52.6% | -98.0% | -105.2% | -59.1% | -181.6% | -488.1% | -588.1% | · | -71153.9% | -47272.4% | -33090.4% | |
| Pretax Margin | -134.2% | -52.6% | -97.8% | -105.0% | -59.0% | -181.3% | -488.0% | -588.0% | · | -71063.6% | · | · | |
| EBITDA Margin | -62.1% | -82.2% | -88.7% | -90.5% | -46.8% | -159.0% | -462.8% | -593.0% | · | -71903.9% | -47630.4% | -33120.5% | |
| ROA | -143.7% | -37.8% | -47.8% | -49.8% | -40.1% | -64.6% | -62.7% | -68.4% | -71.5% | -55.4% | -54.2% | -40.0% | |
| ROE | 73.7% | 44.2% | 121.0% | 210.7% | 120.7% | -292.3% | -364.1% | -100.7% | -88.4% | -60.8% | -58.3% | -41.9% | |
| ROIC | 31.0% | 64.3% | 95.3% | 855.7% | 123.6% | -340.5% | -380.4% | -98.2% | -100.9% | -68.3% | · | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.1 | 1.7 | 3.4 | 5.3 | 3.7 | 4.6 | 6.0 | 7.1 | 3.0 | 8.0 | 11.7 | 16.9 | |
| Quick Ratio | 0.9 | 1.0 | 1.1 | 2.8 | 2.9 | 1.6 | 2.9 | 2.5 | 3.0 | 7.9 | 11.6 | 16.7 | |
| Interest Coverage | · | · | -5.4 | -5.7 | -3.8 | -6.3 | -12.1 | -72.2 | · | · | · | -75846.0 |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 1.1 | 0.7 | 0.5 | 0.5 | 0.7 | 0.4 | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 | |
| Receivables Turnover | 5.1 | 5.0 | 3.9 | 4.5 | 11.9 | 10.4 | 10.4 | · | · | · | · | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $-16.00 | $-1.47 | $-1.19 | $-0.15 | $-1.05 | $0.68 | $0.76 | $3.01 | $2.61 | $3.87 | $5.53 | $6.32 | |
| Revenue / Share | $13357.75 | $1145.32 | $1.28 | $1.92 | · | · | · | · | · | · | · | · | |
| Cash Flow / Share | $-6892.46 | $-1005.34 | $-0.81 | $-1.83 | · | · | · | · | · | · | · | · | |
| Cash / Share | $3.31 | $0.50 | $0.45 | $1.19 | $2.51 | $1.16 | $1.97 | $1.94 | $1.39 | $1.19 | $1.63 | $4.61 | |
| EPS (TTM) | $-17.93 | $-14.00 | $-18.79 | $-2.02 | $-1.65 | $-2.72 | · | · | · | · | · | · |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 0.57% | -0.55% | -7.0% | -25.1% | 94.1% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -2.4% | -11.5% | 10.5% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 6.2% | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $146M | $145M | $146M | $157M | $210M | $108M | $41M | $30M | $2M | $154.0K | $250.0K | $229.0K | |
| Net Income TTM | $-196M | $-76M | $-143M | $-165M | $-124M | $-196M | $-200M | $-178M | $-129M | $-110M | $-118M | $-76M | |
| Market Cap | $135M | $1.28B | $1.49B | $5.77B | $7.31B | $17.16B | $18.80B | $8.55B | $7.13B | $5.91B | $7.13B | $18.36B | |
| P/E | -0.4 | -0.7 | -0.7 | -25.2 | -58.5 | -85.4 | · | · | · | · | · | · | |
| P/S | 0.9 | 8.8 | 10.2 | 36.8 | 34.8 | 158.8 | 459.7 | 281.8 | 4444.1 | 38351.8 | 28512.5 | 80170.6 | |
| P/B | -0.5 | -6.9 | -10.9 | -346.7 | -91.7 | 339.6 | 377.7 | 46.7 | 55.1 | 36.4 | 35.9 | 88.8 | |
| P / Tangible Book | · | · | · | · | · | 339.6 | · | · | · | · | · | · | |
| P / Cash Flow | -1.8 | -10.0 | -16.1 | -38.6 | -68.2 | -107.1 | -98.5 | -53.7 | -96.8 | -70.0 | -75.8 | -356.9 | |
| P / FCF | -1.8 | -10.0 | -16.1 | -38.6 | -68.1 | -107.0 | -98.4 | -52.9 | -96.7 | -69.9 | -74.7 | -338.2 | |
| Earnings Yield | -243.6% | -138.1% | -144.8% | -4.0% | -1.7% | -1.2% | · | · | · | · | · | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $33M | $35M | $34M | $44M | $38M | $30M | $31M | $39M | $43M | $33M | $34M | $36M | $38M | $39M | $34M | $36M | |
| R&D Expense | $29M | $34M | $28M | $31M | $33M | $35M | $33M | $36M | $38M | $35M | $39M | $36M | $31M | $32M | $31M | $31M | |
| SG&A Expense | $26M | $27M | $23M | $27M | $28M | $27M | $27M | $28M | $31M | $30M | $31M | $31M | $34M | $36M | $35M | $35M | |
| Operating Expenses | $56M | $62M | $52M | $59M | $62M | $63M | $62M | $65M | $71M | $67M | $72M | $67M | $67M | $70M | $67M | $67M | |
| Operating Income | $-23M | $-27M | $-18M | $-15M | $-24M | $-33M | $-31M | $-26M | $-28M | $-34M | $-38M | $-31M | $-30M | $-31M | $-34M | $-31M | |
| Interest Expense | · | · | · | · | · | · | · | · | $9M | $6M | · | $6M | $6M | $6M | · | $6M | |
| Interest Income | $722.0K | $511.0K | $607.0K | $553.0K | $613.0K | $1M | $1M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $1M | $658.0K | |
| Other Non-op | $-32M | $16M | $-10M | $-7M | $-2M | $20M | $10M | $4M | $14M | $196.0K | $-211.0K | $89.0K | $30.0K | $-264.0K | $-13.0K | $16.0K | |
| Pretax Income | $-67M | $-22M | $-102M | $-33M | $-37M | $-23M | $-31M | $-32M | $24M | $-37M | $-42M | $-34M | $-33M | $-34M | $-38M | $-36M | |
| Income Tax | $0 | $1.0K | $-67.0K | $34.0K | $40.0K | $36.0K | $-109.0K | $28.0K | $67.0K | $71.0K | $130.0K | $12.0K | $127.0K | $54.0K | $73.0K | $45.0K | |
| Net Income | $-67M | $-22M | $-102M | $-33M | $-37M | $-23M | $-31M | $-32M | $24M | $-37M | $-42M | $-35M | $-33M | $-34M | $-39M | $-36M | |
| EPS (Basic) | $-2.32 | $-1.02 | $-7.02 | $-3.82 | $-4.32 | $-2.77 | $-2.97 | $-3.85 | $2.26 | $-4.85 | $-17.90 | $-0.30 | $-0.29 | $-0.30 | $-0.42 | $-0.45 | |
| EPS (Diluted) | $-2.32 | $-1.24 | $-7.02 | $-3.82 | $-4.32 | $-2.77 | $-2.33 | $-3.85 | $-2.97 | $-4.85 | $-17.90 | $-0.30 | $-0.29 | $-0.30 | $-0.42 | $-0.45 | |
| Shares (Basic) | 28,938 | 22,014 | · | 8,669 | 8,620 | 8,470 | · | 8,336 | 8,069 | 7,700 | · | 114,401 | 114,207,000 | 113,481,000 | · | 80,210,000 | |
| Shares (Diluted) | 28,938 | 24,715 | · | 8,669 | 8,620 | 8,470 | · | 8,336 | 10,295 | 7,700 | · | 114,401 | 114,207,000 | 113,481,000 | · | 80,210,000 | |
| EBITDA | · | $-27M | · | $-15M | $-24M | $-33M | · | $-26M | $-28M | $-34M | · | $-31M | $-30M | $-31M | · | $-31M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $55M | $91M | $61M | $38M | $39M | $39M | $62M | $73M | $85M | $31M | $52M | $44M | $81M | $84M | $135M | $71M | |
| Receivables | $30M | $23M | $26M | $32M | $33M | $35M | $31M | $32M | $38M | $31M | · | $38M | $32M | $35M | · | $27M | |
| Inventory | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $3M | $3M | · | $3M | $4M | $4M | · | $4M | |
| Prepaid Expense | $7M | $9M | $9M | $8M | $8M | $10M | $12M | $15M | $15M | $15M | · | $13M | $18M | $18M | · | $10M | |
| Other Current Assets | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $31M | |
| Current Assets | $106M | $126M | $103M | $90M | $98M | $120M | $156M | $185M | $209M | $198M | · | $263M | $291M | $319M | · | $223M | |
| PP&E (Net) | $94.0K | $91.0K | $104.0K | $122.0K | $244.0K | $322.0K | $400.0K | $495.0K | $628.0K | $719.0K | · | $686.0K | $766.0K | $849.0K | · | $1M | |
| PP&E (Gross) | · | · | $6M | · | · | · | $7M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $6M | · | · | · | $7M | · | · | · | · | · | · | · | · | · | |
| Total Assets | $111M | $131M | $108M | $96M | $105M | $128M | $164M | $189M | $214M | $204M | · | $270M | $298M | $326M | · | $231M | |
| Accounts Payable | $8M | $4M | $4M | $5M | $3M | $6M | $5M | $6M | $3M | $5M | · | $943.0K | $2M | $9M | · | $813.0K | |
| Accrued Liabilities | $79M | $76M | $64M | $66M | $63M | $57M | $61M | $50M | $50M | $55M | · | $56M | $52M | $47M | · | $56M | |
| Current Liabilities | $134M | $117M | $92M | $87M | $99M | $90M | $92M | $61M | $58M | $65M | · | $62M | $59M | $62M | · | $62M | |
| Capital Leases | $5M | $5M | $6M | $6M | $6M | $6M | $7M | $0 | $955.0K | $2M | · | $4M | $4M | $5M | · | $7M | |
| Other Non-current Liabilities | $336.0K | $278.0K | $11M | $14M | $8M | $5M | $2M | $6M | $4M | $3M | · | $1M | $2M | $1M | · | · | |
| Total Liabilities | $441M | $397M | $401M | $365M | $344M | $334M | $350M | $349M | $346M | $373M | · | $370M | $369M | $371M | · | $372M | |
| Common Stock | $14.0K | $14.0K | $14.0K | $13.0K | $13.0K | $13.0K | $13.0K | $13.0K | $13.0K | $12.0K | · | $12.0K | $12.0K | $12.0K | · | $8.0K | |
| Retained Earnings | $-1.85B | $-1.78B | $-1.76B | $-1.66B | $-1.62B | $-1.59B | $-1.56B | $-1.53B | $-1.50B | $-1.52B | · | $-1.45B | $-1.41B | $-1.38B | · | $-1.31B | |
| AOCI | $41.0K | $43.0K | $71.0K | $-259.0K | $-251.0K | $-321.0K | $-356.0K | $-222.0K | $-605.0K | $-518.0K | · | $-742.0K | $-783.0K | $-419.0K | · | $-752.0K | |
| Stockholders' Equity | $-330M | $-266M | $-293M | $-269M | $-239M | $-206M | $-186M | $-160M | $-132M | $-169M | $-136M | $-100M | $-71M | $-45M | $-17M | $-140M | |
| Liabilities + Equity | $111M | $131M | $108M | $96M | $105M | $128M | $164M | $189M | $214M | $204M | · | $270M | $298M | $326M | · | $231M | |
| Shares Outstanding | 22,680,000 | 22,544,000 | 18,311,000 | 8,702,000 | 8,647,000 | 8,568,000 | 8,413,000 | 125,303,000 | 124,635,000 | 116,457,000 | · | 114,523,000 | 114,340,000 | 113,971,000 | · | 81,027,000 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $2M | $3M | $4M | $3M | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $6M | $5M | $6M | $7M | |
| Operating Cash Flow | $-25M | $-23M | $-12M | $-6M | $-19M | $-39M | $-26M | $-19M | $-38M | $-44M | $-19M | $-30M | $-26M | $-19M | $-27M | $-28M | |
| CapEx | · | · | $0 | $0 | $0 | $0 | $-53.0K | $0 | $0 | $195.0K | $0 | $0 | $0 | $0 | $0 | $39.0K | |
| Investing Cash Flow | $-10M | $3M | $5M | $5M | $18M | $15M | $15M | $7M | $51M | $22M | $27M | $-8M | $21M | $-32M | $-65M | $12M | |
| Stock Issued | $0 | $20M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $20M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-898.0K | $50M | $30M | $0 | $356.0K | $0 | $680.0K | $0 | · | · | $264.0K | $0 | $860.0K | $0 | $156M | $6M | |
| Net Change in Cash | $-36M | $30M | $23M | $-1M | $-48.0K | $-24M | $-10M | $-12M | $54M | $-22M | $9M | $-37M | $-4M | $-51M | $64M | $-11M | |
| Free Cash Flow | · | · | · | · | · | $-39M | · | · | · | $-44M | · | · | · | $-19M | · | · | |
| Levered FCF | · | · | · | · | · | · | · | · | · | $-50M | · | · | · | $-25M | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | -76.3% | · | -34.6% | -64.3% | -110.8% | · | -67.8% | -65.7% | -101.9% | · | -86.8% | -78.7% | -79.8% | · | -85.3% | |
| Net Margin | · | -63.9% | · | -75.2% | -98.2% | -78.2% | · | -82.7% | 55.6% | -112.8% | · | -95.8% | -86.8% | -88.2% | · | -100.5% | |
| Pretax Margin | · | -63.8% | · | -75.1% | -98.1% | -78.0% | · | -82.6% | 55.8% | -112.6% | · | -95.8% | -86.5% | -88.0% | · | -100.4% | |
| EBITDA Margin | · | -76.3% | · | -34.6% | -64.3% | -110.8% | · | -67.8% | -65.7% | -101.9% | · | -86.8% | -78.7% | -79.8% | · | -85.3% | |
| ROA | · | -17.3% | · | -23.2% | -23.4% | -14.1% | · | -14.0% | 9.3% | -14.1% | · | -13.8% | -11.8% | -11.0% | · | -15.0% | |
| ROE | · | 9.5% | · | 15.4% | 20.1% | 12.5% | · | 24.7% | -23.4% | 34.9% | · | 28.7% | 34.8% | 53.2% | · | 27.3% | |
| ROIC | · | 10.1% | · | 5.7% | 10.2% | 16.2% | · | 16.5% | 21.2% | 20.0% | · | 31.1% | 41.7% | 68.5% | · | 22.0% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | 1.1 | · | 1.0 | 1.0 | 1.3 | · | 3.0 | 3.6 | 3.0 | · | 4.2 | 4.9 | 5.2 | · | 3.6 | |
| Quick Ratio | · | 1.0 | · | 0.8 | 0.7 | 0.8 | · | 1.7 | 2.1 | 0.9 | · | 1.3 | 1.9 | 1.9 | · | 1.6 | |
| Interest Coverage | · | · | · | · | · | · | · | · | -3.1 | -5.7 | · | -5.1 | -5.1 | -5.4 | · | -5.0 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | 0.3 | · | 0.3 | 0.2 | 0.2 | · | 0.2 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | |
| Receivables Turnover | · | 1.2 | · | 1.4 | 1.1 | 0.9 | · | 1.1 | 1.2 | 1.0 | · | 1.1 | 1.3 | 1.3 | · | 1.6 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | · | $-11.78 | · | $-30.94 | $-27.63 | $-24.03 | · | $-1.27 | $-1.06 | $-1.45 | · | $-0.88 | $-0.62 | $-0.40 | · | $-1.73 | |
| Revenue / Share | · | $1418.81 | · | $5080.63 | $4400.12 | $3543.68 | · | $310.24 | $0.28 | $0.29 | · | $0.31 | $0.33 | $0.34 | · | $0.45 | |
| Cash Flow / Share | · | $-919.60 | · | · | · | $-4602.60 | · | · | · | $-0.38 | · | · | · | $-0.17 | · | · | |
| Cash / Share | · | $4.03 | · | $4.33 | $4.48 | $4.53 | · | $0.58 | $0.68 | $0.26 | · | $0.38 | $0.71 | $0.74 | · | $0.88 | |
| EPS (TTM) | $-12.15 | $-16.40 | · | $-13.24 | $-13.27 | $-11.92 | · | $-29.57 | $-26.02 | $-23.34 | · | $-1.31 | $-1.46 | $-1.79 | · | $-1.08 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $147M | $151M | · | $143M | $137M | $142M | · | $148M | $146M | $140M | · | $146M | $146M | $148M | · | $250M | |
| Net Income TTM | $-116M | $-195M | · | $-125M | $-124M | $-63M | · | $-87M | $-90M | $-146M | · | $-140M | $-142M | $-158M | · | $-88M | |
| Market Cap | · | $126M | · | $57M | $37M | $32M | · | $1.56B | $1.62B | $2.64B | · | $2.30B | $3.07B | $6.65B | · | $6.64B | |
| P/E | -0.8 | -0.3 | · | -0.5 | -0.3 | -0.3 | · | -0.4 | -0.5 | -1.0 | · | -15.3 | -18.4 | -32.6 | · | -75.8 | |
| P/S | · | 0.8 | · | 0.4 | 0.3 | 0.2 | · | 10.5 | 11.1 | 18.8 | · | 15.8 | 21.0 | 44.9 | · | 26.6 | |
| P/B | · | -0.5 | · | -0.2 | -0.2 | -0.2 | · | -9.8 | -12.3 | -15.6 | · | -22.9 | -43.1 | -147.2 | · | -47.3 | |
| P / Cash Flow | · | -5.5 | · | · | · | -0.8 | · | · | · | -60.3 | · | · | · | -351.7 | · | · | |
| Earnings Yield | -147.4% | -294.4% | · | -202.5% | -307.9% | -318.7% | · | -237.5% | -199.8% | -103.0% | · | -6.5% | -5.4% | -3.1% | · | -1.3% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $146M | $145M | $146M | $157M | $210M |
| Operating Margin % | -62.1% | -82.2% | -88.7% | -90.5% | -46.8% |
| Net Income | $-196M | $-76M | $-143M | $-165M | $-124M |
| Diluted EPS | $-17.93 | $-14.00 | $-18.79 | $-2.02 | $-1.65 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 1.1 | 1.7 | 3.4 | 5.3 | 3.7 |
| Quick Ratio | 0.9 | 1.0 | 1.1 | 2.8 | 2.9 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-75M | $-128M | $-93M | $-150M | $-107M |
Institutional owners (13F) 112 filers · $215.6M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
112
Value held
$215.6M
New positions
39
Exited positions
17
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 39 (-2 vs prior Q) | 17 (+4 vs prior Q) | 32 (-5 vs prior Q) | 20 (+11 vs prior Q) | -2.2M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $18,732,549 | 1,917,354 | 8.69% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $14,863,316 | 1,521,322 | 6.89% | Shares |
| ACORN CAPITAL ADVISORS, LLC | $14,831,964 | 1,518,113 | 6.88% | Shares |
| GOLDMAN SACHS GROUP INC | $13,918,908 | 1,424,658 | 6.46% | Shares |
| BlackRock, Inc. | $13,861,666 | 1,418,799 | 6.43% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $9,369,225 | 958,979 | 4.35% | Shares |
| Catalio Capital Management, LP | $9,192,153 | 940,855 | 4.26% | Shares |
| Avidity Partners Management LP | $9,032,238 | 924,487 | 4.19% | Shares |
| TWO SIGMA INVESTMENTS, LP | $6,792,729 | 695,264 | 3.15% | Shares |
| Kalehua Capital Management LLC | $6,698,742 | 685,644 | 3.11% | Shares |
| NEA Management Company, LLC | $5,635,141 | 576,780 | 2.61% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $5,191,417 | 531,231 | 2.41% | Shares |
| Ghisallo Capital Management LLC | $4,885,000 | 500,000 | 2.27% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,736,496 | 484,800 | 2.20% | Call option |
| Soleus Capital Management, L.P. | $4,298,800 | 440,000 | 1.99% | Shares |
| VANGUARD GROUP INC | $4,118,796 | 559,619 | 1.91% | Shares |
| UBS Group AG | $3,454,135 | 353,545 | 1.60% | Shares |
| STATE STREET CORP | $3,184,932 | 325,991 | 1.48% | Shares |
| Affinity Asset Advisors, LLC | $3,053,125 | 312,500 | 1.42% | Shares |
| Brevan Howard Capital Management LP | $3,026,912 | 309,817 | 1.40% | Shares |
| MILLENNIUM MANAGEMENT LLC | $2,986,455 | 305,676 | 1.39% | Shares |
| Boxer Capital Management, LLC | $2,955,777 | 302,536 | 1.37% | Shares |
| Davidson Kempner Capital Management LP | $2,931,000 | 300,000 | 1.36% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $2,906,184 | 297,460 | 1.35% | Shares |
| Caption Management, LLC | $2,791,289 | 285,700 | 1.29% | Call option |
| Eversept Partners, LP | $2,698,220 | 276,174 | 1.25% | Shares |
| Tetragon Partners GP Ltd | $2,445,431 | 250,300 | 1.13% | Call option |
| JPMORGAN CHASE & CO | $2,093,737 | 207,609 | 0.97% | Shares |
| MORGAN STANLEY | $1,978,485 | 202,506 | 0.92% | Shares |
| Trexquant Investment LP | $1,840,355 | 188,368 | 0.85% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,837,131 | 188,038 | 0.85% | Shares |
| BARCLAYS PLC | $1,620,882 | 165,904 | 0.75% | Shares |
| NORTHERN TRUST CORP | $1,563,258 | 160,006 | 0.73% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,420,568 | 145,401 | 0.66% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1,317,172 | 134,818 | 0.61% | Shares |
| MARSHALL WACE, LLP | $1,254,967 | 128,451 | 0.58% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,057,251 | 108,214 | 0.49% | Shares |
| DLD Asset Management, LP | $989,625 | 101,500 | 0.46% | Put option |
| SILVERBACK ASSET MANAGEMENT LLC | $977,000 | 100,000 | 0.45% | Call option |
| Jump Financial, LLC | $918,380 | 94,000 | 0.43% | Shares |
| Caption Management, LLC | $903,725 | 92,500 | 0.42% | Put option |
| Invesco Ltd. | $882,270 | 90,304 | 0.41% | Shares |
| DLD Asset Management, LP | $780,975 | 80,100 | 0.36% | Call option |
| Connor, Clark & Lunn Investment Management Ltd. | $746,399 | 76,397 | 0.35% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $702,199 | 71,873 | 0.33% | Shares |
| J. Goldman & Co LP | $660,452 | 67,600 | 0.31% | Put option |
| TWO SIGMA ADVISERS, LP | $660,405 | 89,729 | 0.31% | Shares |
| J. Goldman & Co LP | $659,475 | 67,500 | 0.31% | Shares |
| Squarepoint Ops LLC | $623,336 | 63,801 | 0.29% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $605,183 | 61,943 | 0.28% | Shares |
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| James J. Bochnowski (“Bochnowski”), David L. Douglass (“Douglass”), Deepika R. Pakianathan (“Pakianathan”), Douglas A. Roeder (“Roeder”) ×3 filings | June 7, 2017 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 33 insiders · 20 officers · 10 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Richard A. Paulson | President and CEO | May 14, 2026 S | 269,747 | 0 | 2 | $-137,245 |
| Lori Macomber | EVP, CFO & Treasurer | Feb. 3, 2026 S | 85,105 | 0 | 1 | $-10,244 |
| Michael Mason | EVP, CFO & Treasurer | Sept. 4, 2024 S | 391,054 | 0 | 0 | $0 |
| Michael Falvey | EVP, CFO & Treasurer | Jan. 24, 2018 A | · | 0 | 0 | $0 |
| Justin A Renz | EVP, CFO & Treasurer | Jan. 20, 2017 A | 19,173 | 0 | 0 | $0 |
| Kristin Abate | Chief Accounting Officer | Oct. 1, 2026 S | 23,404 | 0 | 6 | $-8,183 |
| Stuart Poulton | EVP, Chief Development Officer | July 28, 2026 S | 94,632 | 0 | 4 | $-56,432 |
| Sohanya Roshan Cheng | EVP & Chief Commercial Officer | May 14, 2026 S | 107,940 | 0 | 2 | $-46,402 |
| Michael Mano | EVP, CLO&Secretary | May 14, 2026 S | 94,398 | 0 | 2 | $-35,707 |
| Reshma Rangwala | EVP & Chief Medical Officer | May 14, 2026 S | 56,829 | 0 | 3 | $-55,561 |
| Stephen Mitchener | SVP, Chief Business Officer | March 1, 2023 S | 128,313 | 0 | 0 | $0 |
| Sharon Shacham | Chief Scientific Officer | March 29, 2022 A | 958,131 | 0 | 0 | $0 |
| Ran Frenkel | EVP, Chief Dev. Officer | Feb. 28, 2022 A | 168,290 | 0 | 0 | $0 |
| Jatin Shah | EVP, Chief Medical Officer | Feb. 17, 2022 S | 129,450 | 0 | 0 | $0 |
| John Demaree | Chief Commercial Officer | Feb. 25, 2021 A | 23,995 | 0 | 0 | $0 |
| Tanya Lewis | EVP, Chief Reg. Affairs | Feb. 25, 2021 A | 45,401 | 0 | 0 | $0 |
| Christopher Brett Primiano | EVP, CBO, GC & Secretary | Dec. 1, 2020 M | 4,523 | 0 | 0 | $0 |
| Cameron Peters | VP of Finance | Feb. 15, 2019 A | · | 0 | 0 | $0 |
| Anand Varadan | EVP, Chief Commercial Officer | Feb. 15, 2019 A | · | 0 | 0 | $0 |
| Paul Brannelly | SVP, FINANCE & ADMIN, TREAS | May 15, 2014 P | 66,136 | 0 | 0 | $0 |
| Zhen Su | Director | May 21, 2026 A | 15,508 | 0 | 0 | $0 |
| Christy J. Oliger | Director | May 21, 2026 A | 15,508 | 0 | 0 | $0 |
| Mansoor Raza Mirza | Director | May 28, 2025 A | 0 | 0 | 0 | $0 |
| Peter Honig | Director | May 24, 2023 A | · | 0 | 0 | $0 |
| Michael Kauffman | Director | Feb. 28, 2022 A | 898,131 | 0 | 0 | $0 |
| Mikael Dolsten | Director | May 21, 2021 A | · | 0 | 0 | $0 |
| Scott J. Garland | Director | June 6, 2019 A | · | 0 | 0 | $0 |
| Carsten Thiel | Director | Aug. 31, 2018 A | · | 0 | 0 | $0 |
| Kenneth E Weg | Director | June 15, 2017 A | 5,000 | 0 | 0 | $0 |
| Chen Schor | · | May 21, 2026 A | 15,508 | 0 | 0 | $0 |
| Barry E Greene | · | May 21, 2026 A | 16,415 | 0 | 0 | $0 |
| Deepika Pakianathan | · | May 21, 2026 A | 15,508 | 0 | 0 | $0 |
| Garen G Bohlin | · | May 21, 2026 A | 18,517 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 14 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0.22% | 57,877 SH | Oct. 2, 2026 | Daily |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0.01% | 35,695 SH | Oct. 2, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 115,151 SH | Aug. 19, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.01% | 14,746 SH | Aug. 19, 2026 | Daily |
| IWC · iShares Trust | 0.01% | 66,498 SH | Sept. 11, 2026 | Daily |
| RSSL · Global X Funds | 0.00% | 9,500 NS | July 31, 2026 | N-PORT |
| IWM · iShares Trust | 0.00% | 481,328 SH | Sept. 11, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.00% | 31,663 SH | Oct. 2, 2026 | Daily |
| IWO · iShares Trust | 0.00% | 27,942 SH | Sept. 11, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 263,084 SH | Aug. 19, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 677,729 SH | Aug. 19, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.00% | 3,188 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 1,733 SH | Aug. 19, 2026 | Daily |
| IWN · iShares Trust | · | 152,603 SH | Sept. 11, 2026 | Daily |
KPTI Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 11 analysts
BUY
Median target
$7.50
+834.9%
3 27.3%
Strong Buy
6 54.5%
Buy
2 18.2%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
4 analysts · 2026-09-30Mean target $7.25 +803.8%
← Below all targets
Current price $0.80
Low$3.00
Mean$7.25
High$11.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| KPTI | $135M | -0.4 | 0.57% | -134.2% | 73.7% | · |
| ACTU | $142M | -5.8 | · | · | -843.5% | · |
| JSPR | · | -0.5 | · | · | · | · |
| NEUP | $24M | -1.4 | -92.5% | -1145.7% | -49.5% | · |
| SHPH | $4M | -0.3 | 0.00% | · | -400.1% | · |
| DYAI | · | -4.1 | -11.6% | · | · | · |
| CLRB | · | -0.4 | · | · | · | · |
| MRKR | $25M | -1.9 | -46.2% | -343.0% | -89.1% | · |
| KTTA | · | · | · | · | · | · |
Latest News Recent headlines mentioning this company
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Source: SEC 10-Q filed Aug 13, 2026