PHAT — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $135,261,406 | 12,466,489 | 16.52% | Shares |
| Medicxi Ventures Management (Jersey) Ltd | $80,990,606 | 7,464,572 | 9.89% | Shares |
| VANGUARD GROUP INC | $52,709,931 | 3,177,211 | 6.44% | Shares |
| BlackRock, Inc. | $49,097,648 | 4,525,129 | 6.00% | Shares |
| Invesco Ltd. | $43,722,581 | 4,029,731 | 5.34% | Shares |
| Carlyle Group Inc. | $37,940,367 | 3,496,808 | 4.63% | Shares |
| MILLENNIUM MANAGEMENT LLC | $36,627,799 | 3,375,834 | 4.47% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $28,827,842 | 2,656,944 | 3.52% | Shares |
| FRANKLIN RESOURCES INC | $21,383,482 | 1,970,828 | 2.61% | Shares |
| NEA Management Company, LLC | $21,267,834 | 1,960,169 | 2.60% | Shares |
| 683 Capital Management, LLC | $20,072,501 | 1,850,000 | 2.45% | Shares |
| GOLDMAN SACHS GROUP INC | $19,291,647 | 1,778,032 | 2.36% | Shares |
| STATE STREET CORP | $17,211,605 | 1,586,323 | 2.10% | Shares |
| Catalys Pacific, LLC | $16,208,316 | 1,493,854 | 1.98% | Shares |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $15,871,000 | 1,462,738 | 1.94% | Shares |
| WASATCH ADVISORS LP | $14,897,577 | 1,340,916 | 1.82% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $14,277,589 | 1,315,687 | 1.74% | Shares |
| Ensign Peak Advisors, Inc | $11,413,256 | 1,051,913 | 1.39% | Shares |
| Propel Bio Management, LLC | $11,396,384 | 1,050,358 | 1.39% | Shares |
| Point72 Asset Management, L.P. | $11,090,794 | 1,022,193 | 1.35% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $8,643,446 | 796,631 | 1.06% | Shares |
| SummitTX Capital, L.P. | $8,566,618 | 789,550 | 1.05% | Shares |
| HSBC HOLDINGS PLC | $7,701,936 | 709,695 | 0.94% | Shares |
| MARSHALL WACE, LLP | $7,227,078 | 666,090 | 0.88% | Shares |
| EcoR1 Capital, LLC | $6,781,250 | 625,000 | 0.83% | Shares |
| PERCEPTIVE ADVISORS LLC | $5,772,200 | 532,000 | 0.70% | Shares |
| TWO SIGMA INVESTMENTS, LP | $5,631,975 | 519,076 | 0.69% | Shares |
| CITADEL ADVISORS LLC | $5,216,680 | 480,800 | 0.64% | Call option |
| NORTHERN TRUST CORP | $4,972,565 | 458,301 | 0.61% | Shares |
| StepStone Group LP | $4,689,364 | 422,085 | 0.57% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $4,547,170 | 419,094 | 0.56% | Shares |
| Woodline Partners LP | $4,004,214 | 369,052 | 0.49% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,847,117 | 354,573 | 0.47% | Shares |
| AMERIPRISE FINANCIAL INC | $3,189,673 | 293,979 | 0.39% | Shares |
| JPMORGAN CHASE & CO | $2,991,978 | 275,251 | 0.37% | Shares |
| Simplify Asset Management Inc. | $2,704,547 | 249,267 | 0.33% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $2,456,440 | 226,400 | 0.30% | Shares |
| JANE STREET GROUP, LLC | $2,307,860 | 212,706 | 0.28% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,281,755 | 210,300 | 0.28% | Call option |
| UBS Group AG | $2,219,618 | 204,573 | 0.27% | Shares |
| NewEdge Advisors, LLC | $2,212,988 | 203,962 | 0.27% | Shares |
| Avidity Partners Management LP | $2,170,000 | 200,000 | 0.27% | Shares |
| MORGAN STANLEY | $2,169,013 | 199,909 | 0.26% | Shares |
| Jump Financial, LLC | $2,081,746 | 191,866 | 0.25% | Shares |
| Opaleye Management Inc. | $2,013,641 | 185,589 | 0.25% | Shares |
| CITADEL ADVISORS LLC | $2,006,176 | 184,901 | 0.25% | Shares |
| Trexquant Investment LP | $1,886,641 | 173,884 | 0.23% | Shares |
| Jones Hill Capital LP | $1,752,123 | 161,486 | 0.21% | Shares |
| Bank of New York Mellon Corp | $1,652,595 | 152,313 | 0.20% | Shares |
| WELLS FARGO & COMPANY/MN | $1,649,221 | 152,002 | 0.20% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,638,513 | 151,015 | 0.20% | Shares |
| XTX Topco Ltd | $1,473,777 | 135,832 | 0.18% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $1,463,677 | 134,901 | 0.18% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $1,435,281 | 132,284 | 0.18% | Shares |
| DIADEMA PARTNERS LP | $1,409,958 | 129,950 | 0.17% | Shares |
| Nuveen, LLC | $1,379,328 | 127,127 | 0.17% | Shares |
| SIG BROKERAGE, LP | $1,345,400 | 124,000 | 0.16% | Call option |
| Engineers Gate Manager LP | $1,283,088 | 118,257 | 0.16% | Shares |
| Virtus Investment Advisers, LLC | $1,216,708 | 112,139 | 0.15% | Shares |
| Russell Investments Group, Ltd. | $1,114,879 | 102,754 | 0.14% | Shares |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1,105,968 | 101,745 | 0.14% | Shares |
| Stratos Wealth Partners, LTD. | $1,085,000 | 100,000 | 0.13% | Shares |
| Swiss National Bank | $1,071,980 | 98,800 | 0.13% | Shares |
| D. E. Shaw & Co., Inc. | $1,037,911 | 95,660 | 0.13% | Shares |
| GILDER GAGNON HOWE & CO LLC | $956,254 | 88,134 | 0.12% | Shares |
| Stonepine Capital Management, LLC | $922,358 | 85,010 | 0.11% | Shares |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $838,879 | 77,316 | 0.10% | Shares |
| JANE STREET GROUP, LLC | $837,620 | 77,200 | 0.10% | Call option |
| Campbell & CO Investment Adviser LLC | $746,035 | 68,759 | 0.09% | Shares |
| Penn Mutual Asset Management | $681,402 | 62,802 | 0.08% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $675,771 | 62,283 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $654,740 | 60,346 | 0.08% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $619,804 | 55,788 | 0.08% | Shares |
| Birchview Capital, LP | $596,750 | 55,000 | 0.07% | Shares |
| CITIGROUP INC | $574,453 | 52,945 | 0.07% | Shares |
| STIFEL FINANCIAL CORP | $573,228 | 52,832 | 0.07% | Shares |
| Creative Planning | $572,337 | 52,750 | 0.07% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $561,889 | 51,787 | 0.07% | Shares |
| ALLIANCEBERNSTEIN L.P. | $547,612 | 49,290 | 0.07% | Shares |
| DEUTSCHE BANK AG\ | $544,725 | 50,205 | 0.07% | Shares |
| Pale Fire Capital SE | $539,386 | 49,713 | 0.07% | Shares |
| NOMURA HOLDINGS INC | $532,735 | 49,100 | 0.07% | Put option |
| Man Group plc | $528,167 | 48,679 | 0.06% | Shares |
| RAYMOND JAMES FINANCIAL INC | $521,061 | 48,024 | 0.06% | Shares |
| Persistent Asset Partners Ltd | $517,143 | 47,663 | 0.06% | Shares |
| AlphaQuest LLC | $468,668 | 28,250 | 0.06% | Shares |
| ADAR1 Capital Management, LLC | $465,465 | 42,900 | 0.06% | Shares |
| Quantbot Technologies LP | $463,892 | 42,755 | 0.06% | Shares |
| BARCLAYS PLC | $453,280 | 41,777 | 0.06% | Shares |
| NOMURA HOLDINGS INC | $434,000 | 40,000 | 0.05% | Shares |
| Y-Intercept (Hong Kong) Ltd | $432,318 | 39,845 | 0.05% | Shares |
| Fiduciary Trust Co | $387,681 | 35,731 | 0.05% | Shares |
| Nebula Research & Development LLC | $363,816 | 37,937 | 0.04% | Shares |
| ALLSTATE CORP | $356,694 | 32,875 | 0.04% | Shares |
| Legal & General Group Plc | $355,207 | 32,738 | 0.04% | Shares |
| Squarepoint Ops LLC | $342,806 | 31,595 | 0.04% | Shares |
| CITADEL ADVISORS LLC | $337,435 | 31,100 | 0.04% | Put option |
| VANGUARD ASSET MANAGEMENT, Ltd | $309,290 | 28,506 | 0.04% | Shares |
| MetLife Investment Management, LLC | $304,961 | 28,107 | 0.04% | Shares |
| Kera Capital Partners, Inc. | $291,062 | 26,826 | 0.04% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $280,342 | 25,838 | 0.03% | Shares |
| Caption Management, LLC | $260,400 | 24,000 | 0.03% | Call option |
| Caption Management, LLC | $260,400 | 24,000 | 0.03% | Put option |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $245,720 | 22,647 | 0.03% | Shares |
| COMMONWEALTH EQUITY SERVICES, LLC | $244,500 | 22,535 | 0.03% | Shares |
| Summit Financial Wealth Advisors, LLC | $240,252 | 22,143 | 0.03% | Shares |
| JANUS HENDERSON GROUP PLC | $239,403 | 21,500 | 0.03% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $236,198 | 18,731 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $225,344 | 20,769 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $220,255 | 20,300 | 0.03% | Put option |
| INSPIRION WEALTH ADVISORS, LLC | $209,794 | 19,914 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $192,316 | 17,725 | 0.02% | Shares |
| State of Wyoming | $191,383 | 17,639 | 0.02% | Shares |
| PROFUND ADVISORS LLC | $187,455 | 17,277 | 0.02% | Shares |
| Jain Global LLC | $178,341 | 16,437 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $175,206 | 16,148 | 0.02% | Shares |
| State of New Jersey Common Pension Fund D | $172,775 | 15,924 | 0.02% | Shares |
| Pathstone Holdings, LLC | $162,750 | 15,000 | 0.02% | Shares |
| LAZARD ASSET MANAGEMENT LLC | $159,180 | 14,671 | 0.02% | Shares |
| Brevan Howard Capital Management LP | $158,399 | 14,599 | 0.02% | Shares |
| KLP KAPITALFORVALTNING AS | $151,900 | 14,000 | 0.02% | Shares |
| GROUP ONE TRADING LLC | $150,609 | 13,881 | 0.02% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $147,896 | 13,631 | 0.02% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $147,441 | 13,589 | 0.02% | Shares |
| Rafferty Asset Management, LLC | $138,403 | 12,756 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $137,719 | 12,693 | 0.02% | Shares |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | $130,200 | 12,000 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $123,560 | 11,388 | 0.02% | Shares |
| Vanguard Investments Australia, Ltd. | $122,345 | 11,276 | 0.01% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $116,855 | 10,770 | 0.01% | Shares |
| Allworth Financial LP | $113,307 | 10,443 | 0.01% | Shares |
| Private Advisor Group, LLC | $110,453 | 10,180 | 0.01% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $94,308 | 8,692 | 0.01% | Shares |
| FMR LLC | $89,290 | 8,230 | 0.01% | Shares |
| Kera Capital Partners, Inc. | $54,250 | 5,000 | 0.01% | Call option |
| Fulcrum Asset Management LLP | $48,458 | 4,458 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $48,424 | 4,463 | 0.01% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $45,560 | 4,250 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $38,702 | 3,567 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $28,515 | 2,628 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $24,749 | 2,281 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $24,000 | 2,258 | 0.00% | Shares |
| HUNTINGTON NATIONAL BANK | $23,610 | 2,176 | 0.00% | Shares |
| GW&K Investment Management, LLC | $23,510 | 2,166,838 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $21,049 | 1,940 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $20,799 | 1,917 | 0.00% | Shares |
| CWM, LLC | $20,709 | 1,864 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $18,109 | 1,669 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $15,884 | 1,464 | 0.00% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $9,722 | 896 | 0.00% | Shares |
| Sterling Capital Management LLC | $8,203 | 756 | 0.00% | Shares |
| Larson Financial Group LLC | $7,942 | 732 | 0.00% | Shares |
| Aster Capital Management (DIFC) Ltd | $5,512 | 508 | 0.00% | Shares |
| MassMutual Private Wealth & Trust, FSB | $4,633 | 427 | 0.00% | Shares |
| GAMMA Investing LLC | $4,340 | 400 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $3,711 | 342 | 0.00% | Shares |
| US BANCORP \DE\ | $3,005 | 277 | 0.00% | Shares |
| Truvestments Capital LLC | $2,441 | 225 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $2,365 | 218 | 0.00% | Shares |
| Lindbrook Capital, LLC | $1,593 | 254 | 0.00% | Shares |
| Quarry LP | $1,378 | 127 | 0.00% | Shares |
| Parallel Advisors, LLC | $1,085 | 100 | 0.00% | Shares |
| Optiver Holding B.V. | $976 | 90 | 0.00% | Shares |
| True Wealth Design, LLC | $955 | 88 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $879 | 81 | 0.00% | Shares |
| KBC Group NV | $837 | 77,139 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $714 | 65,722 | 0.00% | Shares |
| Arax Advisory Partners | $456 | 42 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $327 | 30,138 | 0.00% | Shares |
| ELEVATION WEALTH PARTNERS, LLC | $217 | 20 | 0.00% | Shares |
| HAP Trading, LLC | $90 | 150,000 | 0.00% | Put option |
| Stone House Investment Management, LLC | $87 | 8 | 0.00% | Shares |
| CANADA LIFE ASSURANCE Co | $74 | 6,818 | 0.00% | Shares |
| Clearstead Advisors, LLC | $55 | 5 | 0.00% | Shares |
| Strategic Wealth Advisors LLC | $16 | 1,000 | 0.00% | Shares |
| Covestor Ltd | $0 | 29 | 0.00% | Shares |