PRTA Prothena Corporation plc - Ordinary Shares
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 6, 2026
$8.36
· of 52w range
· above low
· to high
$7.7352w low
$11.8052w high
Market Cap (MRQ)
$433M
P/E (TTM)
-10.1
EPS (TTM)
$-0.83
Revenue (TTM)
$55M
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52W Range
$8–$12
Analyst Rating
BUY
Price Target
$21
P/E
-10.1
ROE
-14.4%
Net Profit Margin
-80.7%
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PRTA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$8.36
Market Cap (MRQ)
$433M
P/E (TTM)
-10.1
EPS (TTM)
$-0.83
Revenue (TTM)
$55M
ROE (TTM)
-14.4%
52W Range
$8–$12
PRTA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue$10M2016-12-31 → 2025-12-31
EPS$-4.532019-12-31 → 2025-12-31
Net margin-80.7%2016-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | PRTA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E (TTM) | -10.15Y avg ≈-2.0 | ≈-2.0 | · | · | |
| P/S (TTM) | 7.95Y avg ≈29.9 | ≈29.9 | · | · | |
| P/B (MRQ) | 1.55Y avg ≈3.4 | ≈3.4 | · | · | |
| Price / Cash Flow | -2.85Y avg ≈-5.3 | ≈-5.3 | · | · | |
| Price / Tangible Book | 1.65Y avg ≈3.4 | ≈3.4 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | PRTA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Operating Margin (TTM) | -101.8%5Y avg ≈-549.6% | ≈-549.6% | · | · | |
| EBITDA Margin (TTM) | -100.3%5Y avg ≈-547.0% | ≈-547.0% | · | · | |
| Pretax Margin (TTM) | -81.3%5Y avg ≈-508.4% | ≈-508.4% | · | · | |
| Net Profit Margin (TTM) | -80.7%5Y avg ≈-591.1% | ≈-591.1% | · | · | |
| ROA (TTM) | -12.5%5Y avg ≈-19.7% | ≈-19.7% | · | · | |
| ROE (TTM) | -14.4%5Y avg ≈-22.5% | ≈-22.5% | · | · | |
| ROIC | -93.0%5Y avg ≈-31.9% | ≈-31.9% | · | · |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | PRTA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 25.05Y avg ≈12.2 | ≈12.2 | · | · | |
| Quick Ratio | 7.55Y avg ≈11.9 | ≈11.9 | · | · |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | PRTA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | -92.8%5Y avg ≈4673.2% | ≈4673.2% | · | · | |
| Revenue CAGR 3Y | -43.6%5Y avg ≈106.3% | ≈106.3% | · | · | |
| Revenue CAGR 5Y | 62.6% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | PRTA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.05Y avg ≈0.2 | ≈0.2 | · | · | |
| Revenue / Employee | ≈$144.5K | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
45.4%
Next Report
Nov 04, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 3, 2026 | $-0.36 | $-0.40 | 9.7% |
| March 31, 2026 | May 13, 2026 | $0.61 | $-0.36 | 271.7% |
| Dec. 31, 2025 | $-0.40 | $-0.57 | 29.8% | |
| Sept. 30, 2025 | $-0.68 | $-0.70 | 3.0% | |
| June 30, 2025 | $-1.73 | $-1.34 | -28.9% | |
| March 31, 2025 | $-1.12 | $-0.99 | -12.8% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| R&D Expense | $135M | $223M | $221M | $136M | $82M | $75M | $51M | $101M | $135M | $120M | $58M | $38M | |
| SG&A Expense | $59M | $67M | $62M | $50M | $46M | $39M | $36M | $42M | $48M | $41M | $23M | $19M | |
| Operating Expenses | $224M | $290M | $282M | $185M | $129M | $114M | $87M | $160M | $183M | $161M | $82M | $58M | |
| Operating Income | $-215M | $-155M | $-191M | $-132M | $72M | $-113M | $-86M | $-159M | $-155M | $-160M | $-80M | $-7M | |
| Other Non-op | $-328.0K | $-185.0K | $-458.0K | $-397.0K | $-96.0K | $-62.0K | $196.0K | $48.0K | $-2M | $15.0K | $-170.0K | $231.0K | |
| Pretax Income | $-201M | $-129M | $-160M | $-126M | $72M | $-111M | $-77M | $-156M | $-158M | $-159M | $-80M | $-6M | |
| Income Tax | $43M | $-7M | $-13M | $-9M | $5M | $-283.0K | $379.0K | $-470.0K | $-4M | $1M | $701.0K | $811.0K | |
| Net Income | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| EPS (Basic) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.51 | $-2.78 | $-1.95 | · | · | · | · | · | |
| EPS (Diluted) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 | $-2.78 | $-1.95 | · | · | · | · | · | |
| Shares (Basic) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 44,228,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| Shares (Diluted) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 48,464,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| EBITDA | $-214M | $-154M | $-190M | $-131M | $73M | $-111M | $-84M | $-156M | $-152M | $-157M | $-79M | $-6M |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $308M | $471M | $619M | $710M | $579M | $295M | $376M | $428M | $418M | $387M | $371M | $294M | |
| Receivables | · | $0 | $5M | $0 | $0 | $15.0K | $68.0K | $2.0K | $240.0K | $178.0K | $509.0K | $2M | |
| Prepaid Expense | $8M | $14M | $14M | $9M | $6M | $3M | $3M | $4M | $8M | $4M | $6M | $4M | |
| Other Current Assets | · | · | · | · | · | · | $3M | $4M | · | · | · | · | |
| Current Assets | $315M | $485M | $639M | $719M | $585M | $299M | $378M | $431M | $426M | $391M | $377M | $299M | |
| PP&E (Net) | $2M | $3M | $4M | $2M | $2M | $3M | $4M | $53M | $55M | $56M | $4M | $3M | |
| PP&E (Gross) | $9M | $11M | $11M | $13M | $12M | $12M | $12M | $63M | $63M | $64M | $9M | $8M | |
| Accum. Depreciation | $7M | $8M | $7M | $11M | $10M | $9M | $8M | $11M | $8M | $8M | $5M | $5M | |
| Other Non-current Assets | $482.0K | $4M | $6M | $11M | $2M | $333.0K | $1M | $813.0K | $3M | $2M | $1M | $0 | |
| Total Assets | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Accounts Payable | $6M | $8M | $25M | $9M | $4M | $4M | $1M | $1M | $14M | $13M | $5M | $5M | |
| Current Liabilities | $41M | $49M | $57M | $50M | $33M | $26M | $18M | $15M | $37M | $41M | $22M | $12M | |
| Capital Leases | $5M | $8M | $11M | $0 | $6M | $12M | $18M | $0 | · | · | · | · | |
| Other Non-current Liabilities | · | · | $0 | $553.0K | $553.0K | $553.0K | $553.0K | $553.0K | $0 | $0 | $126.0K | $0 | |
| Total Liabilities | $46M | $60M | $135M | $136M | $143M | $149M | $146M | $176M | $89M | $95M | $25M | $14M | |
| Common Stock | $538.0K | $538.0K | $537.0K | $521.0K | $466.0K | $399.0K | $399.0K | $399.0K | $385.0K | $348.0K | $317.0K | $274.0K | |
| Paid-in Capital | $1.63B | $1.59B | $1.54B | $1.45B | $1.18B | $967M | $944M | $921M | $849M | $654M | $489M | $338M | |
| Retained Earnings | $-1.35B | $-1.10B | $-980M | $-833M | $-716M | $-783M | $-672M | $-598M | $-442M | $-289M | $-129M | $-48M | |
| Stockholders' Equity | $280M | $487M | $561M | $622M | $466M | $184M | $273M | $323M | $407M | $365M | $361M | $290M | |
| Liabilities + Equity | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Shares Outstanding | 53,832,982 | 53,826,982 | 53,682,117 | 52,103,608 | 46,660,294 | 39,921,413 | 39,898,561 | 39,863,711 | 38,482,764 | 34,752,116 | 31,744,102 | 27,388,005 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $895.0K | $893.0K | $928.0K | $744.0K | $1M | $2M | $2M | $3M | $3M | $2M | $806.0K | $743.0K | |
| Stock-based Comp | $38M | $46M | $41M | $31M | $25M | $22M | $24M | $27M | $27M | $25M | $10M | $6M | |
| Deferred Tax | $43M | $-9M | $-16M | $-11M | $5M | $-2M | $-1M | $-2M | $-2M | $-3M | $-963.0K | $-1M | |
| Restructuring | · | · | · | · | · | · | $-61.0K | $15M | · | · | · | · | |
| Other Non-cash | $-1M | $-65M | $-13M | $-13M | $-5M | $9M | $808.0K | $99M | $-6M | $19M | $8M | $1M | |
| Operating Cash Flow | $-164M | $-150M | $-134M | $-109M | $93M | $-80M | $-53M | $-28M | $-131M | $-116M | $-59M | $-683.0K | |
| Investing Cash Flow | $-138.0K | $-298.0K | $-3M | $-464.0K | $-575.0K | $-196.0K | $-547.0K | $-2M | $-4M | $-17M | $-1M | $-499.0K | |
| Stock Issued | · | · | · | · | $78M | $0 | $0 | $0 | $150M | $129M | $131M | $117M | |
| Net Stock Activity | · | · | · | · | $78M | · | $0 | $0 | $150M | $129M | $131M | $117M | |
| Financing Cash Flow | $-139.0K | $2M | $45M | $241M | $190M | $215.0K | $228.0K | $40M | $165M | $153M | $137M | $118M | |
| Net Change in Cash | · | · | · | · | · | · | · | · | · | · | $77M | $117M | |
| Taxes Paid | $931.0K | $3M | $2M | $3M | $580.0K | $1M | $2M | $-995.0K | $294.0K | · | · | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% | -13216.2% | -10527.9% | -16634.0% | -564.2% | -15121.8% | -4974.3% | -13.1% | |
| Net Margin | -2520.6% | -90.5% | -160.9% | -217.0% | 33.4% | -13029.8% | -9542.6% | -16297.9% | -556.8% | -15176.1% | -5016.3% | -14.1% | |
| Pretax Margin | -2073.8% | -95.4% | -175.6% | -233.0% | 35.9% | -13063.0% | -9496.1% | -16347.1% | -572.7% | -15067.7% | -4972.7% | -12.5% | |
| EBITDA Margin | -2207.2% | -113.7% | -208.1% | -242.7% | 36.4% | -13038.7% | -10335.8% | -16297.3% | -553.0% | -14891.7% | -4924.1% | -11.6% | |
| ROA | -55.9% | -19.7% | -20.2% | -17.1% | 14.2% | -29.5% | -16.9% | -31.3% | -32.0% | -37.9% | -23.4% | -2.9% | |
| ROE | -63.6% | -23.3% | -24.9% | -21.5% | 20.6% | -48.6% | -26.1% | -42.6% | -39.7% | -44.1% | -24.8% | -3.1% | |
| ROIC | -93.0% | -30.1% | -31.2% | -19.7% | 14.4% | -61.1% | -31.6% | -49.0% | -37.1% | -44.0% | -22.4% | -2.6% |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 | 11.6 | 21.4 | 28.9 | 11.4 | 9.5 | 17.0 | 24.9 | |
| Quick Ratio | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 | 11.4 | 21.2 | 28.7 | 11.2 | 9.4 | 16.7 | 24.5 |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | 0.1 | 0.1 | 0.4 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.2 | |
| Receivables Turnover | · | 52.4 | 35.4 | · | 26743.6 | 20.6 | 23.3 | 7.9 | 131.7 | 3.1 | 1.4 | 58.8 |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $5.21 | $9.05 | $10.46 | $11.94 | $9.99 | $4.61 | $6.84 | $8.10 | $10.58 | $10.51 | $11.36 | $10.58 | |
| Revenue / Share | $0.18 | $2.51 | $1.72 | $1.14 | $4.14 | · | · | · | · | · | · | · | |
| Cash Flow / Share | $-3.04 | $-2.79 | $-2.52 | $-2.30 | $1.91 | · | · | · | · | · | · | · | |
| Cash / Share | $5.71 | $8.76 | $11.53 | $13.63 | $12.41 | $7.40 | $9.42 | $10.73 | $10.85 | $11.13 | $11.67 | $10.72 | |
| EPS (TTM) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 | $-2.78 | $-1.95 | $-3.94 | $-4.06 | $-4.66 | $-2.63 | $-0.12 |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -92.8% | 47.9% | 69.5% | -73.1% | 23414.3% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -43.6% | -12.3% | 374.9% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 62.6% | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| Net Income TTM | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| Market Cap | $514M | $746M | $1.95B | $3.14B | $2.31B | $479M | $632M | $411M | $1.44B | $1.71B | $2.16B | $569M | |
| P/E | -2.1 | -6.1 | -13.2 | -24.4 | 35.8 | -4.3 | -8.1 | -2.6 | -9.2 | -10.6 | -25.9 | -173.0 | |
| P/S | 53.1 | 5.5 | 21.4 | 58.2 | 11.5 | 562.1 | 775.9 | 429.9 | 52.4 | 1620.3 | 1345.4 | 11.2 | |
| P/B | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | 2.3 | 1.3 | 3.5 | 4.7 | 6.0 | 2.0 | |
| P / Tangible Book | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | · | · | · | · | · | · | |
| P / Cash Flow | -3.1 | -5.0 | -14.6 | -28.8 | 24.9 | -6.0 | -11.9 | -14.5 | -11.0 | -14.6 | -34.6 | -832.5 | |
| Earnings Yield | -47.4% | -16.4% | -7.6% | -4.1% | 2.8% | -23.2% | -12.3% | -38.2% | -10.8% | -9.5% | -3.9% | -0.58% |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1M | $51M | $21.0K | $2M | $4M | $3M | $2M | $970.0K | $132M | $50.0K | $85M | $4M | $2M | $2M | $1M | $1M | |
| R&D Expense | $9M | $13M | $15M | $29M | $41M | $51M | $50M | $51M | $58M | $64M | $58M | $56M | $45M | $40M | $32M | $27M | |
| SG&A Expense | $11M | $13M | $13M | $13M | $16M | $18M | $17M | $17M | $16M | $17M | $17M | $15M | $14M | $12M | $13M | $12M | |
| Operating Expenses | $22M | $21M | $24M | $43M | $89M | $68M | $67M | $67M | $74M | $82M | $75M | $71M | $58M | $52M | $45M | $39M | |
| Operating Income | $-21M | $30M | $-24M | $-40M | $-85M | $-66M | $-65M | $-67M | $58M | $-82M | $10M | $-67M | $-56M | $-50M | $-43M | $-38M | |
| Other Non-op | $-33.0K | $271.0K | $-22.0K | $-23.0K | $-143.0K | $-140.0K | $9.0K | $-66.0K | $-51.0K | $-77.0K | $-15.0K | $-97.0K | $-141.0K | $2.0K | $-2.0K | $-70.0K | |
| Pretax Income | $-19M | $33M | $-22M | $-37M | $-81M | $-61M | $-60M | $-60M | $65M | $-74M | $19M | $-59M | $-50M | $-48M | $-43M | $-38M | |
| Income Tax | $2.0K | $1.0K | $10.0K | $-371.0K | $45M | $-1M | $-2M | $-835.0K | $-2M | $-2M | $-3M | $-4M | $-3M | $-3M | $-1M | $-2M | |
| Net Income | $-19M | $33M | $-22M | $-37M | $-126M | $-60M | $-58M | $-59M | $67M | $-72M | $22M | $-55M | $-47M | $-46M | $-41M | $-36M | |
| EPS (Basic) | $-0.36 | $0.61 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.07 | $-1.10 | $1.24 | $-1.34 | $0.41 | $-1.03 | $-0.89 | $-0.97 | $-0.88 | $-0.78 | |
| EPS (Diluted) | $-0.36 | $0.60 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.05 | $-1.10 | $1.22 | $-1.34 | $0.38 | $-1.03 | $-0.89 | $-0.97 | $-0.88 | $-0.78 | |
| Shares (Basic) | 52,145,000 | 53,708,000 | · | 53,830,000 | 53,827,000 | 53,827,000 | · | 53,790,000 | 53,767,000 | 53,714,000 | 53,559,000 | 53,121,000 | 52,501,000 | 46,986,000 | 46,805,000 | 46,704,000 | |
| Shares (Diluted) | 52,145,000 | 54,109,000 | · | 53,830,000 | 53,827,000 | 53,827,000 | · | 53,790,000 | 55,043,000 | 53,714,000 | 58,004,000 | 53,121,000 | 52,501,000 | 46,986,000 | 46,805,000 | 46,704,000 | |
| EBITDA | $-21M | $30M | · | $-40M | $-85M | $-65M | · | $-67M | $58M | $-81M | $10M | $-67M | $-56M | $-50M | $-43M | $-38M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $288M | $329M | $308M | $331M | $371M | $418M | $471M | $519M | $564M | $547M | $671M | $659M | $686M | $496M | $509M | $543M | |
| Receivables | · | · | · | · | · | · | · | $0 | $0 | $0 | $5M | $524.0K | · | · | · | · | |
| Prepaid Expense | $4M | $10M | $8M | $9M | $14M | $18M | $14M | $16M | $22M | $18M | $13M | $16M | $14M | $29M | $12M | $13M | |
| Current Assets | $292M | $339M | $315M | $340M | $385M | $436M | $485M | $535M | $586M | $566M | $691M | $677M | $700M | $525M | $521M | $556M | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $4M | $2M | $2M | $2M | $2M | $2M | $2M | |
| PP&E (Gross) | $9M | $9M | $9M | $9M | $10M | $11M | $11M | $11M | $11M | $11M | $14M | $14M | $13M | $13M | $13M | $13M | |
| Accum. Depreciation | $7M | $7M | $7M | $7M | $7M | $8M | $8M | $8M | $8M | $8M | $12M | $12M | $11M | $11M | $11M | $11M | |
| Other Non-current Assets | $482.0K | $482.0K | $482.0K | $482.0K | $478.0K | $494.0K | $4M | $4M | $4M | $4M | $10M | $11M | $11M | $4M | $4M | $2M | |
| Total Assets | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | $747M | $721M | $742M | $554M | $550M | $581M | |
| Accounts Payable | $2M | $4M | $6M | $11M | $12M | $16M | $8M | $10M | $9M | $14M | $19M | $14M | $13M | $10M | $8M | $9M | |
| Current Liabilities | $12M | $33M | $41M | $51M | $68M | $48M | $49M | $46M | $47M | $43M | $53M | $72M | $49M | $51M | $40M | $36M | |
| Capital Leases | $4M | $5M | $5M | $6M | $7M | $8M | $8M | $9M | $10M | $10M | $9M | · | · | $2M | $3M | $5M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | $553.0K | $553.0K | $553.0K | |
| Total Liabilities | $16M | $37M | $46M | $58M | $75M | $58M | $60M | $61M | $64M | $121M | $130M | $139M | $134M | $150M | $142M | $143M | |
| Common Stock | $517.0K | $530.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $537.0K | $536.0K | $535.0K | $527.0K | $479.0K | $468.0K | $467.0K | |
| Paid-in Capital | $1.62B | $1.63B | $1.63B | $1.62B | $1.61B | $1.60B | $1.59B | $1.58B | $1.57B | $1.55B | $1.53B | $1.52B | $1.49B | $1.24B | $1.20B | $1.19B | |
| Retained Earnings | $-1.33B | $-1.31B | $-1.35B | $-1.32B | $-1.29B | $-1.16B | $-1.10B | $-1.04B | $-985M | $-1.05B | $-913M | $-934M | $-880M | $-839M | $-794M | $-752M | |
| Stockholders' Equity | $287M | $313M | $280M | $295M | $324M | $438M | $487M | $534M | $582M | $502M | $617M | $582M | $607M | $405M | $407M | $439M | |
| Liabilities + Equity | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | $747M | $721M | $742M | $554M | $550M | $581M | |
| Shares Outstanding | 51,744,327 | 53,077,225 | 53,832,982 | 53,829,982 | 53,826,982 | 53,826,982 | 53,826,982 | 53,808,732 | 53,771,845 | 53,720,455 | 53,638,615 | 53,493,467 | 52,678,178 | 47,885,755 | 46,809,841 | 46,749,766 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $197.0K | $184.0K | $218.0K | $229.0K | $225.0K | $223.0K | $221.0K | $226.0K | $231.0K | $215.0K | $229.0K | $222.0K | $201.0K | $182.0K | $184.0K | $182.0K | |
| Stock-based Comp | $8M | $7M | $7M | $7M | $12M | $11M | $11M | $11M | $12M | $12M | $11M | $10M | $9M | $8M | $8M | $8M | |
| Restructuring | · | $-4M | · | $500.0K | $33M | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $-11M | · | · | · | $-4M | · | · | · | $-13M | · | · | $-10M | · | · | $-9M | |
| Operating Cash Flow | $-25M | $29M | $-23M | $-41M | $-46M | $-53M | $-48M | $-45M | $16M | $-73M | $10M | $-45M | $-47M | $-31M | $-35M | $-37M | |
| Investing Cash Flow | $-652.0K | $0 | $0 | $-10.0K | $-86.0K | $-42.0K | $-43.0K | $-9.0K | $-143.0K | $-103.0K | $-442.0K | $-771.0K | $-48.0K | $-130.0K | $-161.0K | $-22.0K | |
| Financing Cash Flow | $-16M | $-7M | $0 | $-17.0K | $-74.0K | $-48.0K | $-59.0K | $333.0K | $444.0K | $836.0K | $3M | $19M | $23M | $18M | $1M | $1M | |
| Taxes Paid | $-616.0K | $0 | $-10.0K | $2.0K | $939.0K | $0 | $760.0K | $836.0K | $2M | $20.0K | $50.0K | $334.0K | $0 | $751.0K | $2M | $9.0K |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2089.2% | 58.8% | · | -1666.3% | -1914.4% | -2319.0% | · | -6857.0% | 44.2% | -163056.0% | 12.2% | -1654.7% | -2596.8% | -3317.9% | -3293.4% | -3290.9% | |
| Net Margin | -1839.9% | 64.0% | · | -1513.1% | -2845.4% | -2128.5% | · | -6082.6% | 50.7% | -144478.0% | 25.8% | -1358.4% | -2160.6% | -3016.7% | -3143.6% | -3147.4% | |
| Pretax Margin | -1839.7% | 64.1% | · | -1528.5% | -1831.8% | -2170.2% | · | -6168.7% | 49.1% | -148880.0% | 22.2% | -1465.6% | -2294.9% | -3191.6% | -3244.8% | -3292.4% | |
| EBITDA Margin | -2089.2% | 59.2% | · | -1666.3% | -1914.4% | -2311.1% | · | -6857.0% | 44.2% | -162626.0% | 12.2% | -1654.7% | -2587.5% | -3317.9% | -3293.4% | -3275.1% | |
| ROA | -5.3% | 7.7% | · | -7.7% | -24.1% | -10.8% | · | -8.8% | 9.8% | -10.6% | 3.4% | -8.6% | -7.1% | -7.7% | -8.4% | -7.5% | |
| ROE | -6.1% | 8.7% | · | -8.8% | -27.8% | -12.8% | · | -10.2% | 11.5% | -13.0% | 4.3% | -11.0% | -9.0% | -10.2% | -11.9% | -10.8% | |
| ROIC | -7.4% | 9.6% | · | -13.5% | -40.5% | -14.7% | · | -12.3% | 10.3% | -15.8% | 1.9% | -10.6% | -8.7% | -11.8% | -10.3% | -8.3% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 25.0 | 10.4 | · | 6.6 | 5.7 | 9.0 | · | 11.5 | 12.5 | 13.1 | 12.9 | 9.5 | 14.3 | 10.4 | 13.0 | 15.2 | |
| Quick Ratio | 24.7 | 10.1 | · | 6.4 | 5.5 | 8.6 | · | 11.2 | 12.1 | 12.6 | 12.7 | 9.2 | 14.0 | 9.8 | 12.7 | 14.9 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.2 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | 0.4 | 503.9 | 100.0 | 32.4 | 15.3 | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $5.54 | $5.89 | · | $5.48 | $6.03 | $8.13 | · | $9.93 | $10.82 | $9.35 | $11.51 | $10.87 | $11.53 | $8.45 | $8.70 | $9.39 | |
| Revenue / Share | $0.02 | $0.94 | · | $0.04 | $0.08 | $0.05 | · | $0.02 | $2.40 | $0.00 | $1.46 | $0.08 | $0.04 | $0.03 | $0.03 | $0.02 | |
| Cash Flow / Share | · | $0.53 | · | · | · | $-0.99 | · | · | · | $-1.36 | · | · | $-0.90 | · | · | $-0.80 | |
| Cash / Share | $5.57 | $6.21 | · | $6.15 | $6.90 | $7.76 | · | $9.65 | $10.49 | $10.17 | $12.51 | $12.32 | $13.03 | $10.35 | $10.87 | $11.61 | |
| EPS (TTM) | $-0.83 | $-2.81 | · | $-5.19 | $-5.61 | $-2.05 | · | $-2.44 | $-0.96 | $-3.21 | $-1.38 | $-2.73 | $-2.58 | $-3.05 | $0.05 | $1.51 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $55M | $58M | · | $12M | $10M | $138M | · | $133M | $217M | $89M | $141M | $58M | $55M | $5M | $143M | $202M | |
| Net Income TTM | $-44M | $-151M | · | $-280M | $-303M | $-110M | · | $-132M | $-51M | $-172M | $-73M | $-141M | $-128M | $-156M | $-1M | $67M | |
| Market Cap | $507M | $516M | · | $525M | $327M | $666M | · | $900M | $1.11B | $1.33B | $2.59B | $3.65B | $2.55B | $2.90B | $1.27B | $1.71B | |
| P/E | -11.8 | -3.5 | · | -1.9 | -1.1 | -6.0 | · | -6.9 | -21.5 | -7.7 | -35.0 | -25.0 | -18.8 | -19.9 | 543.0 | 24.2 | |
| P/S | 9.3 | 8.9 | · | 44.6 | 31.6 | 4.8 | · | 6.8 | 5.1 | 14.9 | 18.4 | 63.4 | 46.5 | 563.3 | 8.9 | 8.5 | |
| P/B | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | 4.2 | 6.3 | 4.2 | 7.2 | 3.1 | 3.9 | |
| P / Tangible Book | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | 4.2 | 6.3 | 4.2 | 7.2 | 3.1 | 3.9 | |
| P / Cash Flow | · | 17.9 | · | · | · | -12.5 | · | · | · | -18.2 | · | · | -53.8 | · | · | -45.7 | |
| Earnings Yield | -8.5% | -28.9% | · | -53.2% | -92.4% | -16.6% | · | -14.6% | -4.7% | -13.0% | -2.9% | -4.0% | -5.3% | -5.0% | 0.18% | 4.1% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $10M | $135M | $91M | $54M | $201M |
| Operating Margin % | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% |
| Net Income | $-244M | $-122M | $-147M | $-117M | $67M |
| Diluted EPS | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 |
| Quick Ratio | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 |
No data for this statement
Not enough fundamentals data to build this statement yet.
Institutional owners (13F) 208 filers · $480.6M total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
208
Value held
$480.6M
New positions
29
Exited positions
21
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 29 (-2 vs prior Q) | 21 (-1 vs prior Q) | 60 (-7 vs prior Q) | 57 (+3 vs prior Q) | +966K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $70,480,344 | 7,199,218 | 14.67% | Shares |
| Rubric Capital Management LP | $48,950,000 | 5,000,000 | 10.19% | Shares |
| BlackRock, Inc. | $47,657,280 | 4,867,955 | 9.92% | Shares |
| STATE STREET CORP | $23,431,621 | 2,393,424 | 4.88% | Shares |
| VANGUARD GROUP INC | $20,445,681 | 2,140,909 | 4.25% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $16,166,158 | 1,651,293 | 3.36% | Shares |
| D. E. Shaw & Co., Inc. | $15,776,164 | 1,611,457 | 3.28% | Shares |
| ADAR1 Capital Management, LLC | $15,218,898 | 1,554,535 | 3.17% | Shares |
| TWO SIGMA INVESTMENTS, LP | $12,384,223 | 1,264,987 | 2.58% | Shares |
| Palo Alto Investors LP | $11,191,487 | 1,143,155 | 2.33% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $11,024,980 | 1,125,877 | 2.29% | Shares |
| FEDERATED HERMES, INC. | $10,616,286 | 1,084,401 | 2.21% | Shares |
| MORGAN STANLEY | $9,744,465 | 995,348 | 2.03% | Shares |
| GOLDMAN SACHS GROUP INC | $9,591,557 | 979,730 | 2.00% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $9,457,023 | 965,988 | 1.97% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $8,867,349 | 905,651 | 1.85% | Shares |
| Qube Research & Technologies Ltd | $7,745,545 | 791,169 | 1.61% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $6,829,651 | 697,615 | 1.42% | Shares |
| Man Group plc | $6,638,756 | 678,116 | 1.38% | Shares |
| Mariner, LLC | $6,119,684 | 625,095 | 1.27% | Shares |
| Nuveen, LLC | $5,454,568 | 557,157 | 1.14% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $4,698,662 | 479,945 | 0.98% | Shares |
| NORTHERN TRUST CORP | $4,475,243 | 457,124 | 0.93% | Shares |
| Birchview Capital, LP | $4,395,896 | 449,019 | 0.91% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,120,611 | 420,900 | 0.86% | Call option |
| Rangeley Capital, LLC | $4,085,073 | 417,270 | 0.85% | Shares |
| TWO SIGMA ADVISERS, LP | $4,081,670 | 427,400 | 0.85% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,484,222 | 355,896 | 0.73% | Shares |
| CITADEL ADVISORS LLC | $3,316,950 | 338,810 | 0.69% | Shares |
| MONIMUS CAPITAL MANAGEMENT, LP | $3,221,419 | 329,052 | 0.67% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $3,091,711 | 315,803 | 0.64% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $2,962,179 | 302,572 | 0.62% | Shares |
| Penbrook Management LLC | $2,660,138 | 271,720 | 0.55% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $2,536,237 | 259,064 | 0.53% | Shares |
| UBS Group AG | $2,363,550 | 241,425 | 0.49% | Shares |
| MACKENZIE FINANCIAL CORP | $2,348,611 | 239,899 | 0.49% | Shares |
| Coppell Advisory Solutions LLC | $2,329,633 | 12 | 0.48% | Shares |
| Squarepoint Ops LLC | $2,192,676 | 223,971 | 0.46% | Shares |
| BANK OF AMERICA CORP /DE/ | $2,038,728 | 208,246 | 0.42% | Shares |
| Focused Wealth Management, Inc | $2,030,887 | 207,445 | 0.42% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $1,876,674 | 191,693 | 0.39% | Shares |
| MARSHALL WACE, LLP | $1,868,265 | 190,834 | 0.39% | Shares |
| Cubist Systematic Strategies, LLC | $1,863,662 | 190,949 | 0.39% | Shares |
| Quantinno Capital Management LP | $1,550,060 | 158,331 | 0.32% | Shares |
| MILLENNIUM MANAGEMENT LLC | $1,467,521 | 149,900 | 0.31% | Call option |
| DIADEMA PARTNERS LP | $1,463,429 | 149,482 | 0.30% | Shares |
| CITADEL ADVISORS LLC | $1,393,117 | 142,300 | 0.29% | Put option |
| Bank of New York Mellon Corp | $1,310,942 | 133,906 | 0.27% | Shares |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $1,243,232 | 126,990 | 0.26% | Shares |
| Russell Investments Group, Ltd. | $1,193,411 | 121,901 | 0.25% | Shares |
Activists & 5%+ owners 3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×7 filings | May 29, 2025 | 0.00% | Amendment | Passive investment | SEC |
| Woodford Investment Management LLP, Neil Woodford | Oct. 9, 2015 | · | Initial filing | Passive investment | SEC |
| Elan Corporation, plc (2), Elan Science One Limited (2) | Dec. 28, 2012 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 33 insiders · 20 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Gene G. Kinney | President and CEO | July 28, 2026 M | 68,793 | 0 | 0 | $0 |
| Dale B. Schenk | President and CEO | Feb. 24, 2016 A | 14,877 | 0 | 0 | $0 |
| Tran Nguyen | Chief Strategy Officer and CFO | July 28, 2026 M | 40,205 | 0 | 0 | $0 |
| Brandon S. Smith | Chief Operating Officer | July 28, 2026 M | 52,000 | 0 | 0 | $0 |
| Anne Evans Kingston | Chief Strategy Officer | July 29, 2026 S | 55,782 | 0 | 1 | $-64,897 |
| Michael John Isaacs | General Counsel & Company Sec. | July 29, 2026 S | 35,745 | 0 | 1 | $-71,029 |
| Chad J. Swanson | Chief Development Officer | July 28, 2026 M | 40,733 | 0 | 0 | $0 |
| Wagner M. Zago | Chief Scientific Officer | July 28, 2026 M | 34,000 | 0 | 0 | $0 |
| Karin L Walker | Chief Accounting Officer | July 28, 2026 M | 10,000 | 0 | 0 | $0 |
| Michael J Malecek | Chief Legal Officer | March 3, 2026 A | 80,000 | 0 | 0 | $0 |
| David A Ford | Chief People Officer | March 5, 2025 A | · | 0 | 0 | $0 |
| Carol D. Karp | Chief Regulatory Officer | March 5, 2025 A | 0 | 0 | 0 | $0 |
| Hideki Garren | Chief Medical Officer | Feb. 27, 2024 A | 0 | 0 | 0 | $0 |
| Radhika Tripuraneni | Chief Development Officer | Feb. 23, 2022 A | · | 0 | 0 | $0 |
| Arthur W Homan | Chief Legal Officer | June 21, 2018 A | 0 | 0 | 0 | $0 |
| Tara Nickerson | Chief Business Officer | Feb. 21, 2018 A | 2,000 | 0 | 0 | $0 |
| Sarah B. Noonberg | Chief Medical Officer | May 16, 2017 A | · | 0 | 0 | $0 |
| David B. Mcninch | Chief Commercial Officer | Feb. 24, 2016 A | · | 0 | 0 | $0 |
| Martin Koller | Chief Medical Officer | Feb. 24, 2016 A | 0 | 0 | 0 | $0 |
| John Randall Fawcett | Controller | Jan. 29, 2013 A | · | 0 | 0 | $0 |
| William H. Dunn Jr. | Director | May 15, 2026 A | · | 0 | 0 | $0 |
| Dennis J. Selkoe | Director | May 15, 2026 A | 2,845 | 0 | 0 | $0 |
| Shane Cooke | Director | May 15, 2026 A | 0 | 0 | 0 | $0 |
| Lars Ekman | Director | May 15, 2026 A | 243 | 0 | 0 | $0 |
| Daniel G Welch | Director | May 15, 2026 A | · | 0 | 0 | $0 |
| COLLIER RICHARD T | Director | May 15, 2026 A | 1,219 | 0 | 0 | $0 |
| Paula K Cobb | Director | May 14, 2025 A | · | 0 | 0 | $0 |
| Helen Kim | Director | May 14, 2025 A | · | 0 | 0 | $0 |
| Karl Anders Olof Harfstrand | Director | May 17, 2023 A | · | 0 | 0 | $0 |
| Sanjiv Patel | Director | May 18, 2022 A | · | 0 | 0 | $0 |
| Christopher S Henney | Director | July 14, 2021 M | 0 | 0 | 0 | $0 |
| William P Scully | 10% owner | Sept. 29, 2026 P | 214,000 | 12 | 0 | $7,254,950 |
| EcoR1 Capital, LLC | 10% owner | May 6, 2025 S | 5,304,596 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 25 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0.46% | 12,830 SH | Oct. 1, 2026 | Daily |
| IBRN · iShares Trust | 0.44% | 3,678 SH | Sept. 11, 2026 | Daily |
| LABU · Direxion Shares ETF Trust | 0.08% | 49,385 NS | July 31, 2026 | N-PORT |
| IBB · iShares Trust | 0.03% | 351,307 SH | Sept. 11, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.03% | 3,636 SH | Oct. 1, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.02% | 28,906 SH | Aug. 19, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.02% | 52,102 SH | Oct. 1, 2026 | Daily |
| IWO · iShares Trust | 0.02% | 251,677 SH | Sept. 11, 2026 | Daily |
| IWM · iShares Trust | 0.01% | 1,143,145 SH | Sept. 11, 2026 | Daily |
| RSSL · Global X Funds | 0.01% | 21,233 NS | July 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 255,810 SH | Aug. 19, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.01% | 15,431 SH | Aug. 19, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.01% | 129,902 SH | Aug. 19, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.01% | 120,757 NS | July 31, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.01% | 3,714 NS | July 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 5,606 NS | July 31, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 71,109 NS | July 31, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 16,113 NS | July 31, 2026 | N-PORT |
| DFSU · Dimensional ETF Trust | 0.00% | 2,078 NS | July 31, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 53,544 SH | Sept. 11, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 11,064 SH | Sept. 3, 2026 | Daily |
| DFUS · Dimensional ETF Trust | 0.00% | 10,778 NS | July 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 479,945 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 3,260 SH | Aug. 19, 2026 | Daily |
| IWN · iShares Trust | · | 169,673 SH | Sept. 11, 2026 | Daily |
PRTA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 12 analysts
BUY
Median target
$20.00
+139.2%
2 16.7%
Strong Buy
6 50.0%
Buy
3 25.0%
Hold
1 8.3%
Sell
0 0.0%
Strong Sell
12-Month Price Target
5 analysts · 2026-10-03Mean target $21.40 +156.0%
Now
Current price $8.36
Low$8.00
Mean$21.40
High$36.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
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Source: SEC 10-Q filed Aug 6, 2026