PRTA Prothena Corporation plc - Ordinary Shares
$9.19
Price · Aug 19, 2026
Fundamentals as of Aug 6, 2026
52W Range
$8–$12
36% of range
Analyst Rating
BUY
12 analysts
Price Target
$21
+133% upside
P/E (TTM)
-2.0
ROE
-63.6%
Net Profit Margin
-2520.6%
PRTA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$9.19
Market Cap
$495M
P/E (TTM)
-2.0
EPS (TTM)
$-4.53
Revenue (TTM)
$10M
Div Yield
—
ROE
-63.6%
Debt/Equity
—
52W Range
$8 – $12
PRTA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$10M
2016-12-31
→
2025-12-31
EPS
$-4.53
2019-12-31
→
2025-12-31
Free Cash Flow
—
Margins
-2520.6%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
PRTA
Peer Median
P/E (TTM)
-2.0
55.9
P/S (TTM)
51.1
5.5
P/B
1.8
1.8
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
PRTA
Peer Median
Operating Margin
-2216.4%
—
Net Profit Margin
-2520.6%
-14.2%
ROA
-55.9%
-4.2%
ROE
-63.6%
-6.0%
ROIC
-93.0%
—
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
PRTA
Peer Median
Current Ratio
7.7
3.7
Quick Ratio
7.5
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
PRTA
Peer Median
Revenue YoY
-92.8%
—
Revenue CAGR 3Y
-43.6%
—
Revenue CAGR 5Y
62.6%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
PRTA
Peer Median
PRTA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
12 analysts
- Strong Buy 2 16.7%
- Buy 6 50.0%
- Hold 3 25.0%
- Sell 1 8.3%
- Strong Sell 0 0.0%
12-Month Price Target
5 analysts · 2026-08-15
Median
$20.00
Now
$9.19
Low
$8.00
High
$36.00
Median target
$20.00
+117.6%
Mean target
$21.40
+132.9%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.11%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.36 | $-0.40 | 0.04% |
| March 31, 2026 | $0.61 | $-0.36 | 0.97% |
| Dec. 31, 2025 | $-0.40 | $-0.57 | 0.17% |
| Sept. 30, 2025 | $-0.68 | $-0.70 | 0.02% |
| June 30, 2025 | $-1.73 | $-1.34 | -0.39% |
| March 31, 2025 | $-1.12 | $-0.99 | -0.13% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| PRTA | $514M | -2.1 | -92.8% | -2520.6% | -63.6% | — |
| ALKS | $4.63B | 19.6 | -5.2% | 16.4% | 14.0% | — |
| AMRN | $5.81B | -155.1 | -6.6% | -18.2% | -8.4% | 56.6% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| R&D Expense | $135M | $223M | $221M | $136M | $82M | $75M | $51M | $101M | $135M | $120M | $58M | $38M | |
| SG&A Expense | $59M | $67M | $62M | $50M | $46M | $39M | $36M | $42M | $48M | $41M | $23M | $19M | |
| Operating Expenses | $224M | $290M | $282M | $185M | $129M | $114M | $87M | $160M | $183M | $161M | $82M | $58M | |
| Operating Income | $-215M | $-155M | $-191M | $-132M | $72M | $-113M | $-86M | $-159M | $-155M | $-160M | $-80M | $-7M | |
| Other Non-op | $-328.0K | $-185.0K | $-458.0K | $-397.0K | $-96.0K | $-62.0K | $196.0K | $48.0K | $-2M | $15.0K | $-170.0K | $231.0K | |
| Pretax Income | $-201M | $-129M | $-160M | $-126M | $72M | $-111M | $-77M | $-156M | $-158M | $-159M | $-80M | $-6M | |
| Income Tax | $43M | $-7M | $-13M | $-9M | $5M | $-283.0K | $379.0K | $-470.0K | $-4M | $1M | $701.0K | $811.0K | |
| Net Income | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| EPS (Basic) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.51 | $-2.78 | $-1.95 | · | · | · | · | · | |
| EPS (Diluted) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 | $-2.78 | $-1.95 | · | · | · | · | · | |
| Shares (Basic) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 44,228,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| Shares (Diluted) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 48,464,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| EBITDA | $-214M | $-154M | $-190M | $-131M | $73M | $-111M | $-84M | $-156M | $-152M | $-157M | $-79M | $-6M |
Balance Sheet 21
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $308M | $471M | $619M | $710M | $579M | $295M | $376M | $428M | $418M | $387M | $371M | $294M | |
| Receivables | · | $0 | $5M | $0 | $0 | $15.0K | $68.0K | $2.0K | $240.0K | $178.0K | $509.0K | $2M | |
| Prepaid Expense | $8M | $14M | $14M | $9M | $6M | $3M | $3M | $4M | $8M | $4M | $6M | $4M | |
| Other Current Assets | · | · | · | · | · | · | $3M | $4M | · | · | · | · | |
| Current Assets | $315M | $485M | $639M | $719M | $585M | $299M | $378M | $431M | $426M | $391M | $377M | $299M | |
| PP&E (Net) | $2M | $3M | $4M | $2M | $2M | $3M | $4M | $53M | $55M | $56M | $4M | $3M | |
| PP&E (Gross) | $9M | $11M | $11M | $13M | $12M | $12M | $12M | $63M | $63M | $64M | $9M | $8M | |
| Accum. Depreciation | $7M | $8M | $7M | $11M | $10M | $9M | $8M | $11M | $8M | $8M | $5M | $5M | |
| Other Non-current Assets | $482.0K | $4M | $6M | $11M | $2M | $333.0K | $1M | $813.0K | $3M | $2M | $1M | $0 | |
| Total Assets | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Accounts Payable | $6M | $8M | $25M | $9M | $4M | $4M | $1M | $1M | $14M | $13M | $5M | $5M | |
| Current Liabilities | $41M | $49M | $57M | $50M | $33M | $26M | $18M | $15M | $37M | $41M | $22M | $12M | |
| Capital Leases | $5M | $8M | $11M | $0 | $6M | $12M | $18M | $0 | · | · | · | · | |
| Other Non-current Liabilities | · | · | $0 | $553.0K | $553.0K | $553.0K | $553.0K | $553.0K | $0 | $0 | $126.0K | $0 | |
| Total Liabilities | $46M | $60M | $135M | $136M | $143M | $149M | $146M | $176M | $89M | $95M | $25M | $14M | |
| Common Stock | $538.0K | $538.0K | $537.0K | $521.0K | $466.0K | $399.0K | $399.0K | $399.0K | $385.0K | $348.0K | $317.0K | $274.0K | |
| Paid-in Capital | $1.63B | $1.59B | $1.54B | $1.45B | $1.18B | $967M | $944M | $921M | $849M | $654M | $489M | $338M | |
| Retained Earnings | $-1.35B | $-1.10B | $-980M | $-833M | $-716M | $-783M | $-672M | $-598M | $-442M | $-289M | $-129M | $-48M | |
| Stockholders' Equity | $280M | $487M | $561M | $622M | $466M | $184M | $273M | $323M | $407M | $365M | $361M | $290M | |
| Liabilities + Equity | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Shares Outstanding | 53,832,982 | 53,826,982 | 53,682,117 | 52,103,608 | 46,660,294 | 39,921,413 | 39,898,561 | 39,863,711 | 38,482,764 | 34,752,116 | 31,744,102 | 27,388,005 |
Cash Flow 12
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $895.0K | $893.0K | $928.0K | $744.0K | $1M | $2M | $2M | $3M | $3M | $2M | $806.0K | $743.0K | |
| Stock-based Comp | $38M | $46M | $41M | $31M | $25M | $22M | $24M | $27M | $27M | $25M | $10M | $6M | |
| Deferred Tax | $43M | $-9M | $-16M | $-11M | $5M | $-2M | $-1M | $-2M | $-2M | $-3M | $-963.0K | $-1M | |
| Restructuring | · | · | · | · | · | · | $-61.0K | $15M | · | · | · | · | |
| Other Non-cash | $-1M | $-65M | $-13M | $-13M | $-5M | $9M | $808.0K | $99M | $-6M | $19M | $8M | $1M | |
| Operating Cash Flow | $-164M | $-150M | $-134M | $-109M | $93M | $-80M | $-53M | $-28M | $-131M | $-116M | $-59M | $-683.0K | |
| Investing Cash Flow | $-138.0K | $-298.0K | $-3M | $-464.0K | $-575.0K | $-196.0K | $-547.0K | $-2M | $-4M | $-17M | $-1M | $-499.0K | |
| Stock Issued | · | · | · | · | $78M | $0 | $0 | $0 | $150M | $129M | $131M | $117M | |
| Net Stock Activity | · | · | · | · | $78M | · | $0 | $0 | $150M | $129M | $131M | $117M | |
| Financing Cash Flow | $-139.0K | $2M | $45M | $241M | $190M | $215.0K | $228.0K | $40M | $165M | $153M | $137M | $118M | |
| Net Change in Cash | · | · | · | · | · | · | · | · | · | · | $77M | $117M | |
| Taxes Paid | $931.0K | $3M | $2M | $3M | $580.0K | $1M | $2M | $-995.0K | $294.0K | · | · | · |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% | -13216.2% | -10527.9% | -16634.0% | -564.2% | -15121.8% | -4974.3% | -13.1% | |
| Net Margin | -2520.6% | -90.5% | -160.9% | -217.0% | 33.4% | -13029.8% | -9542.6% | -16297.9% | -556.8% | -15176.1% | -5016.3% | -14.1% | |
| Pretax Margin | -2073.8% | -95.4% | -175.6% | -233.0% | 35.9% | -13063.0% | -9496.1% | -16347.1% | -572.7% | -15067.7% | -4972.7% | -12.5% | |
| EBITDA Margin | -2207.2% | -113.7% | -208.1% | -242.7% | 36.4% | -13038.7% | -10335.8% | -16297.3% | -553.0% | -14891.7% | -4924.1% | -11.6% | |
| ROA | -55.9% | -19.7% | -20.2% | -17.1% | 14.2% | -29.5% | -16.9% | -31.3% | -32.0% | -37.9% | -23.4% | -2.9% | |
| ROE | -63.6% | -23.3% | -24.9% | -21.5% | 20.6% | -48.6% | -26.1% | -42.6% | -39.7% | -44.1% | -24.8% | -3.1% | |
| ROIC | -93.0% | -30.1% | -31.2% | -19.7% | 14.4% | -61.1% | -31.6% | -49.0% | -37.1% | -44.0% | -22.4% | -2.6% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 | 11.6 | 21.4 | 28.9 | 11.4 | 9.5 | 17.0 | 24.9 | |
| Quick Ratio | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 | 11.4 | 21.2 | 28.7 | 11.2 | 9.4 | 16.7 | 24.5 |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | 0.1 | 0.1 | 0.4 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.2 | |
| Receivables Turnover | · | 52.4 | 35.4 | · | 26743.6 | 20.6 | 23.3 | 7.9 | 131.7 | 3.1 | 1.4 | 58.8 |
Growth Rates 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -92.8% | 47.9% | 69.5% | -73.1% | 23414.3% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -43.6% | -12.3% | 374.9% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 62.6% | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 9
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| Net Income TTM | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| Market Cap | $514M | $746M | $1.95B | $3.14B | $2.31B | $479M | $632M | $411M | $1.44B | $1.71B | $2.16B | $569M | |
| P/E | -2.1 | -6.1 | -13.2 | -24.4 | 35.8 | -4.3 | -8.1 | -2.6 | -9.2 | -10.6 | -25.9 | -173.0 | |
| P/S | 53.1 | 5.5 | 21.4 | 58.2 | 11.5 | 562.1 | 775.9 | 429.9 | 52.4 | 1620.3 | 1345.4 | 11.2 | |
| P/B | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | 2.3 | 1.3 | 3.5 | 4.7 | 6.0 | 2.0 | |
| P / Tangible Book | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | · | · | · | · | · | · | |
| P / Cash Flow | -3.1 | -5.0 | -14.6 | -28.8 | 24.9 | -6.0 | -11.9 | -14.5 | -11.0 | -14.6 | -34.6 | -832.5 | |
| Earnings Yield | -47.4% | -16.4% | -7.6% | -4.1% | 2.8% | -23.2% | -12.3% | -38.2% | -10.8% | -9.5% | -3.9% | -0.58% |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1M | $51M | $21.0K | $2M | $4M | $3M | $2M | $970.0K | $132M | $50.0K | $316.0K | $85M | $4M | $2M | $50M | $2M | |
| R&D Expense | $9M | $13M | $15M | $29M | $41M | $51M | $50M | $51M | $58M | $64M | $62M | $58M | $56M | $45M | $37M | $40M | |
| SG&A Expense | $11M | $13M | $13M | $13M | $16M | $18M | $17M | $17M | $16M | $17M | $17M | $17M | $15M | $14M | $13M | $12M | |
| Operating Expenses | $22M | $21M | $24M | $43M | $89M | $68M | $67M | $67M | $74M | $82M | $79M | $75M | $71M | $58M | $50M | $52M | |
| Operating Income | $-21M | $30M | $-24M | $-40M | $-85M | $-66M | $-65M | $-67M | $58M | $-82M | $-79M | $10M | $-67M | $-56M | $-72.0K | $-50M | |
| Other Non-op | $-33.0K | $271.0K | $-22.0K | $-23.0K | $-143.0K | $-140.0K | $9.0K | $-66.0K | $-51.0K | $-77.0K | $-205.0K | $-15.0K | $-97.0K | $-141.0K | $-327.0K | $2.0K | |
| Pretax Income | $-19M | $33M | $-22M | $-37M | $-81M | $-61M | $-60M | $-60M | $65M | $-74M | $-71M | $19M | $-59M | $-50M | $3M | $-48M | |
| Income Tax | $2.0K | $1.0K | $10.0K | $-371.0K | $45M | $-1M | $-2M | $-835.0K | $-2M | $-2M | $-3M | $-3M | $-4M | $-3M | $-3M | $-3M | |
| Net Income | $-19M | $33M | $-22M | $-37M | $-126M | $-60M | $-58M | $-59M | $67M | $-72M | $-67M | $22M | $-55M | $-47M | $6M | $-46M | |
| EPS (Basic) | $-0.36 | $0.61 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.07 | $-1.10 | $1.24 | $-1.34 | $-1.25 | $0.41 | $-1.03 | $-0.89 | $0.16 | $-0.97 | |
| EPS (Diluted) | $-0.36 | $0.60 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.05 | $-1.10 | $1.22 | $-1.34 | $-1.22 | $0.38 | $-1.03 | $-0.89 | $0.16 | $-0.97 | |
| Shares (Basic) | 52,145,000 | 53,708,000 | -107,655,000 | 53,830,000 | 53,827,000 | 53,827,000 | -107,499,000 | 53,790,000 | 53,767,000 | 53,714,000 | -105,965,000 | 53,559,000 | 53,121,000 | 52,501,000 | -93,126,000 | 46,986,000 | |
| Shares (Diluted) | 52,145,000 | 54,109,000 | -107,655,000 | 53,830,000 | 53,827,000 | 53,827,000 | -108,775,000 | 53,790,000 | 55,043,000 | 53,714,000 | -110,410,000 | 58,004,000 | 53,121,000 | 52,501,000 | -93,126,000 | 46,986,000 | |
| EBITDA | $-21M | $30M | · | $-40M | $-85M | $-65M | · | $-67M | $58M | $-81M | · | $10M | $-67M | $-56M | · | $-50M |
Balance Sheet 20
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $288M | $329M | $308M | $331M | $371M | $418M | $471M | $519M | $564M | $547M | $619M | $671M | $659M | $686M | $710M | $496M | |
| Receivables | · | · | · | · | · | · | · | $0 | $0 | $0 | · | $5M | $524.0K | · | · | · | |
| Prepaid Expense | $4M | $10M | $8M | $9M | $14M | $18M | $14M | $16M | $22M | $18M | · | $13M | $16M | $14M | · | $29M | |
| Current Assets | $292M | $339M | $315M | $340M | $385M | $436M | $485M | $535M | $586M | $566M | · | $691M | $677M | $700M | · | $525M | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $4M | · | $2M | $2M | $2M | · | $2M | |
| PP&E (Gross) | $9M | $9M | $9M | $9M | $10M | $11M | $11M | $11M | $11M | $11M | · | $14M | $14M | $13M | · | $13M | |
| Accum. Depreciation | $7M | $7M | $7M | $7M | $7M | $8M | $8M | $8M | $8M | $8M | · | $12M | $12M | $11M | · | $11M | |
| Other Non-current Assets | $482.0K | $482.0K | $482.0K | $482.0K | $478.0K | $494.0K | $4M | $4M | $4M | $4M | · | $10M | $11M | $11M | · | $4M | |
| Total Assets | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | · | $747M | $721M | $742M | · | $554M | |
| Accounts Payable | $2M | $4M | $6M | $11M | $12M | $16M | $8M | $10M | $9M | $14M | · | $19M | $14M | $13M | · | $10M | |
| Current Liabilities | $12M | $33M | $41M | $51M | $68M | $48M | $49M | $46M | $47M | $43M | · | $53M | $72M | $49M | · | $51M | |
| Capital Leases | $4M | $5M | $5M | $6M | $7M | $8M | $8M | $9M | $10M | $10M | · | $9M | · | · | · | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | · | $553.0K | |
| Total Liabilities | $16M | $37M | $46M | $58M | $75M | $58M | $60M | $61M | $64M | $121M | · | $130M | $139M | $134M | · | $150M | |
| Common Stock | $517.0K | $530.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $537.0K | · | $536.0K | $535.0K | $527.0K | · | $479.0K | |
| Paid-in Capital | $1.62B | $1.63B | $1.63B | $1.62B | $1.61B | $1.60B | $1.59B | $1.58B | $1.57B | $1.55B | · | $1.53B | $1.52B | $1.49B | · | $1.24B | |
| Retained Earnings | $-1.33B | $-1.31B | $-1.35B | $-1.32B | $-1.29B | $-1.16B | $-1.10B | $-1.04B | $-985M | $-1.05B | · | $-913M | $-934M | $-880M | · | $-839M | |
| Stockholders' Equity | $287M | $313M | $280M | $295M | $324M | $438M | $487M | $534M | $582M | $502M | · | $617M | $582M | $607M | · | $405M | |
| Liabilities + Equity | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | · | $747M | $721M | $742M | · | $554M | |
| Shares Outstanding | 51,744,327 | 53,077,225 | 53,832,982 | 53,829,982 | 53,826,982 | 53,826,982 | 53,826,982 | 53,808,732 | 53,771,845 | 53,720,455 | · | 53,638,615 | 53,493,467 | 52,678,178 | · | 47,885,755 |
Cash Flow 8
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $197.0K | $184.0K | $218.0K | $229.0K | $225.0K | $223.0K | $221.0K | $226.0K | $231.0K | $215.0K | $276.0K | $229.0K | $222.0K | $201.0K | $196.0K | $182.0K | |
| Stock-based Comp | $8M | $7M | $7M | $7M | $12M | $11M | $11M | $11M | $12M | $12M | $11M | $11M | $10M | $9M | $7M | $8M | |
| Restructuring | · | $-4M | · | $500.0K | $33M | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $-11M | · | · | · | $-4M | · | · | · | $-13M | · | · | · | $-10M | · | · | |
| Operating Cash Flow | $-25M | $29M | $-23M | $-41M | $-46M | $-53M | $-48M | $-45M | $16M | $-73M | $-51M | $10M | $-45M | $-47M | $-5M | $-31M | |
| Investing Cash Flow | $-652.0K | $0 | $0 | $-10.0K | $-86.0K | $-42.0K | $-43.0K | $-9.0K | $-143.0K | $-103.0K | $-2M | $-442.0K | $-771.0K | $-48.0K | $-151.0K | $-130.0K | |
| Financing Cash Flow | $-16M | $-7M | $0 | $-17.0K | $-74.0K | $-48.0K | $-59.0K | $333.0K | $444.0K | $836.0K | $483.0K | $3M | $19M | $23M | $221M | $18M | |
| Taxes Paid | $-616.0K | $0 | $-10.0K | $2.0K | $939.0K | $0 | $760.0K | $836.0K | $2M | $20.0K | $1M | $50.0K | $334.0K | $0 | $285.0K | $751.0K |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2089.2% | 58.8% | · | -1666.3% | -1914.4% | -2319.0% | · | -6857.0% | 44.2% | -163056.0% | · | 12.2% | -1654.7% | -2596.8% | · | -3317.9% | |
| Net Margin | -1839.9% | 64.0% | · | -1513.1% | -2845.4% | -2128.5% | · | -6082.6% | 50.7% | -144478.0% | · | 25.8% | -1358.4% | -2160.6% | · | -3016.7% | |
| Pretax Margin | -1839.7% | 64.1% | · | -1528.5% | -1831.8% | -2170.2% | · | -6168.7% | 49.1% | -148880.0% | · | 22.2% | -1465.6% | -2294.9% | · | -3191.6% | |
| EBITDA Margin | -2089.2% | 59.2% | · | -1666.3% | -1914.4% | -2311.1% | · | -6857.0% | 44.2% | -162626.0% | · | 12.2% | -1654.7% | -2587.5% | · | -3317.9% | |
| ROA | -5.3% | 7.7% | · | -7.7% | -24.1% | -10.8% | · | -8.8% | 9.8% | -10.6% | · | 3.4% | -8.6% | -7.1% | · | -7.7% | |
| ROE | -6.1% | 8.7% | · | -8.8% | -27.8% | -12.8% | · | -10.2% | 11.5% | -13.0% | · | 4.3% | -11.0% | -9.0% | · | -10.2% | |
| ROIC | -7.4% | 9.6% | · | -13.5% | -40.5% | -14.7% | · | -12.3% | 10.3% | -15.8% | · | 1.9% | -10.6% | -8.7% | · | -11.8% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 25.0 | 10.4 | · | 6.6 | 5.7 | 9.0 | · | 11.5 | 12.5 | 13.1 | · | 12.9 | 9.5 | 14.3 | · | 10.4 | |
| Quick Ratio | 24.7 | 10.1 | · | 6.4 | 5.5 | 8.6 | · | 11.2 | 12.1 | 12.6 | · | 12.7 | 9.2 | 14.0 | · | 9.8 |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.2 | 0.0 | · | 0.1 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | 0.4 | 503.9 | 100.0 | · | 32.4 | 15.3 | · | · | · |
Valuation (TTM) 9
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $59M | $61M | · | $11M | $140M | $136M | · | $218M | $221M | $91M | · | $93M | $9M | $6M | · | $143M | |
| Net Income TTM | $-148M | $-190M | · | $-282M | $-178M | $-125M | · | $-42M | $-38M | $-152M | · | $-125M | $-188M | $-170M | · | $-14M | |
| Market Cap | $507M | $516M | · | $525M | $327M | $666M | · | $900M | $1.11B | $1.33B | · | $2.59B | $3.65B | $2.55B | · | $2.90B | |
| P/E | -3.5 | -2.7 | · | -1.9 | -1.8 | -5.3 | · | -19.9 | -26.8 | -8.6 | · | -19.2 | -18.1 | -13.8 | · | -121.3 | |
| P/S | 8.6 | 8.5 | · | 49.4 | 2.3 | 4.9 | · | 4.1 | 5.0 | 14.6 | · | 28.0 | 405.1 | 415.1 | · | 20.3 | |
| P/B | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 4.2 | 6.3 | 4.2 | · | 7.2 | |
| P / Tangible Book | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 4.2 | 6.3 | 4.2 | · | 7.2 | |
| P / Cash Flow | · | 17.9 | · | · | · | -12.5 | · | · | · | -18.2 | · | · | · | -53.8 | · | · | |
| Earnings Yield | -28.4% | -36.4% | · | -53.7% | -55.0% | -18.9% | · | -5.0% | -3.7% | -11.6% | · | -5.2% | -5.5% | -7.3% | · | -0.82% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $10M | $135M | $91M | $54M | $201M |
| Operating Margin % | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% |
| Net Income | $-244M | $-122M | $-147M | $-117M | $67M |
| Diluted EPS | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 |
| Quick Ratio | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 |
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Institutional owners (13F) 210 filers · $338.3M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 35 (+8 vs prior Q) | 21 (-1 vs prior Q) | 53 (-11 vs prior Q) | 57 (+4 vs prior Q) | +4.9M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Rubric Capital Management LP | $48,950,000 | 5,000,000 | 14.47% | Shares |
| FMR LLC | $37,822,108 | 3,863,341 | 11.18% | Shares |
| STATE STREET CORP | $23,431,621 | 2,393,424 | 6.93% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $16,166,158 | 1,651,293 | 4.78% | Shares |
| D. E. Shaw & Co., Inc. | $15,776,164 | 1,611,457 | 4.66% | Shares |
| ADAR1 Capital Management, LLC | $15,218,898 | 1,554,535 | 4.50% | Shares |
| TWO SIGMA INVESTMENTS, LP | $12,384,223 | 1,264,987 | 3.66% | Shares |
| Palo Alto Investors LP | $11,191,487 | 1,143,155 | 3.31% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $9,457,023 | 965,988 | 2.80% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $9,448,487 | 964,846 | 2.79% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $8,269,574 | 844,696 | 2.44% | Shares |
| GOLDMAN SACHS GROUP INC | $7,812,254 | 797,983 | 2.31% | Shares |
| Qube Research & Technologies Ltd | $7,745,545 | 791,169 | 2.29% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $6,829,651 | 697,615 | 2.02% | Shares |
| Man Group plc | $6,638,756 | 678,116 | 1.96% | Shares |
| Mariner, LLC | $6,119,684 | 625,095 | 1.81% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $4,698,662 | 479,945 | 1.39% | Shares |
| Birchview Capital, LP | $4,395,896 | 449,019 | 1.30% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,120,611 | 420,900 | 1.22% | Call option |
| Rangeley Capital, LLC | $4,085,073 | 417,270 | 1.21% | Shares |
| TWO SIGMA ADVISERS, LP | $4,081,670 | 427,400 | 1.21% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,484,222 | 355,896 | 1.03% | Shares |
| CITADEL ADVISORS LLC | $3,316,950 | 338,810 | 0.98% | Shares |
| MONIMUS CAPITAL MANAGEMENT, LP | $3,221,419 | 329,052 | 0.95% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $3,091,711 | 315,803 | 0.91% | Shares |
| BlackRock, Inc. | $2,701,923 | 275,988 | 0.80% | Shares |
| Penbrook Management LLC | $2,660,138 | 271,720 | 0.79% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $2,536,237 | 259,064 | 0.75% | Shares |
| MACKENZIE FINANCIAL CORP | $2,348,611 | 239,899 | 0.69% | Shares |
| Coppell Advisory Solutions LLC | $2,329,573 | 6 | 0.69% | Shares |
| VANGUARD GROUP INC | $2,300,834 | 240,925 | 0.68% | Shares |
| Squarepoint Ops LLC | $2,192,676 | 223,971 | 0.65% | Shares |
| Focused Wealth Management, Inc | $2,030,887 | 207,445 | 0.60% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $1,871,319 | 191,146 | 0.55% | Shares |
| Cubist Systematic Strategies, LLC | $1,863,662 | 190,949 | 0.55% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,734,445 | 177,165 | 0.51% | Shares |
| Quantinno Capital Management LP | $1,550,060 | 158,331 | 0.46% | Shares |
| MILLENNIUM MANAGEMENT LLC | $1,467,521 | 149,900 | 0.43% | Call option |
| DIADEMA PARTNERS LP | $1,463,429 | 149,482 | 0.43% | Shares |
| CITADEL ADVISORS LLC | $1,393,117 | 142,300 | 0.41% | Put option |
| FEDERATED HERMES, INC. | $1,384,766 | 141,447 | 0.41% | Shares |
| CITADEL ADVISORS LLC | $1,144,451 | 116,900 | 0.34% | Call option |
| JANE STREET GROUP, LLC | $1,014,244 | 103,600 | 0.30% | Call option |
| AMERICAN CENTURY COMPANIES INC | $887,405 | 90,644 | 0.26% | Shares |
| AMERIPRISE FINANCIAL INC | $844,779 | 86,290 | 0.25% | Shares |
| XTX Topco Ltd | $839,169 | 85,717 | 0.25% | Shares |
| Susquehanna Portfolio Strategies, LLC | $809,731 | 82,710 | 0.24% | Shares |
| ExodusPoint Capital Management, LP | $803,005 | 82,023 | 0.24% | Shares |
| MARTINGALE ASSET MANAGEMENT L P | $771,452 | 78,800 | 0.23% | Shares |
| Trexquant Investment LP | $751,196 | 76,731 | 0.22% | Shares |
| DCF Advisers, LLC | $717,088 | 73,247 | 0.21% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $688,492 | 70,326 | 0.20% | Shares |
| Duncan Williams Asset Management, LLC | $688,051 | 70,281 | 0.20% | Shares |
| ALLIANCEBERNSTEIN L.P. | $672,789 | 69,217 | 0.20% | Shares |
| Campbell & CO Investment Adviser LLC | $669,098 | 68,345 | 0.20% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $646,140 | 66,000 | 0.19% | Put option |
| Assenagon Asset Management S.A. | $614,665 | 62,785 | 0.18% | Shares |
| PINNACLE ASSOCIATES LTD | $567,017 | 57,918 | 0.17% | Shares |
| RHUMBLINE ADVISERS | $547,206 | 55,896 | 0.16% | Shares |
| Schonfeld Strategic Advisors LLC | $492,925 | 50,350 | 0.15% | Shares |
| HSBC HOLDINGS PLC | $492,220 | 49,569 | 0.15% | Shares |
| EDGEWOOD MANAGEMENT LLC | $489,500 | 50,000 | 0.14% | Shares |
| Quinn Opportunity Partners LLC | $489,500 | 50,000 | 0.14% | Shares |
| JANE STREET GROUP, LLC | $465,025 | 47,500 | 0.14% | Put option |
| Seven Fleet Capital Management LP | $423,907 | 43,300 | 0.13% | Shares |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $412,727 | 42,158 | 0.12% | Shares |
| Engineers Gate Manager LP | $404,033 | 41,270 | 0.12% | Shares |
| Rafferty Asset Management, LLC | $395,487 | 40,397 | 0.12% | Shares |
| Virtus Investment Advisers, LLC | $388,271 | 39,660 | 0.11% | Shares |
| SHELTON CAPITAL MANAGEMENT | $386,431 | 39,472 | 0.11% | Shares |
| WELLS FARGO & COMPANY/MN | $384,306 | 39,255 | 0.11% | Shares |
| Persistent Asset Partners Ltd | $372,999 | 38,100 | 0.11% | Shares |
| BARCLAYS PLC | $359,195 | 36,690 | 0.11% | Shares |
| WINTON GROUP Ltd | $298,595 | 30,500 | 0.09% | Shares |
| RBF Capital, LLC | $285,868 | 29,200 | 0.08% | Shares |
| GREAT LAKES ADVISORS, LLC | $281,296 | 28,733 | 0.08% | Shares |
| PNC Financial Services Group, Inc. | $276,920 | 28,286 | 0.08% | Shares |
| MetLife Investment Management, LLC | $253,463 | 25,890 | 0.07% | Shares |
| Aquatic Capital Management LLC | $248,852 | 25,419 | 0.07% | Shares |
| Purkiss Capital Advisors LLC | $245,592 | 25,086 | 0.07% | Shares |
| TUDOR INVESTMENT CORP ET AL | $239,317 | 24,445 | 0.07% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $234,960 | 24,000 | 0.07% | Shares |
| ENVESTNET ASSET MANAGEMENT INC | $224,269 | 22,908 | 0.07% | Shares |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $210,407 | 21,492 | 0.06% | Shares |
| MOGY JOEL R INVESTMENT COUNSEL INC | $203,142 | 20,750 | 0.06% | Shares |
| PROFUND ADVISORS LLC | $201,380 | 20,570 | 0.06% | Shares |
| MORGAN STANLEY | $197,259 | 20,149 | 0.06% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $194,689 | 19,430 | 0.06% | Shares |
| Savant Capital, LLC | $190,192 | 19,503 | 0.06% | Shares |
| Foundation Wealth Management, LLC | $188,322 | 19,236 | 0.06% | Shares |
| Graham Capital Management, L.P. | $181,076 | 18,496 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $178,658 | 18,249 | 0.05% | Shares |
| STRS OHIO | $175,241 | 17,900 | 0.05% | Shares |
| Invesco Ltd. | $172,980 | 17,669 | 0.05% | Shares |
| Ballentine Partners, LLC | $164,403 | 16,793 | 0.05% | Shares |
| Russell Investments Group, Ltd. | $157,276 | 16,065 | 0.05% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $150,629 | 15,386 | 0.04% | Shares |
| Headlands Technologies LLC | $147,604 | 15,077 | 0.04% | Shares |
| CHICAGO TRUST Co NA | $147,408 | 15,057 | 0.04% | Shares |
| Skopos Labs, Inc. | $145,732 | 14,993 | 0.04% | Shares |
Company insiders 33 insiders · 20 officers · 12 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Gene G. Kinney | President and CEO | July 28, 2026 M | 68,793 | 0 | 0 | $0 |
| Dale B. Schenk | President and CEO | Feb. 24, 2016 A | 14,877 | 0 | 0 | $0 |
| Tran Nguyen | Chief Strategy Officer and CFO | July 28, 2026 M | 40,205 | 0 | 0 | $0 |
| Brandon S. Smith | Chief Operating Officer | July 28, 2026 M | 52,000 | 0 | 0 | $0 |
| Anne Evans Kingston | Chief Strategy Officer | July 29, 2026 S | 55,782 | 0 | 1 | $-64,897 |
| Michael John Isaacs | General Counsel & Company Sec. | July 29, 2026 S | 35,745 | 0 | 1 | $-71,029 |
| Chad J. Swanson | Chief Development Officer | July 28, 2026 M | 40,733 | 0 | 0 | $0 |
| Wagner M. Zago | Chief Scientific Officer | July 28, 2026 M | 34,000 | 0 | 0 | $0 |
| Karin L Walker | Chief Accounting Officer | July 28, 2026 M | 10,000 | 0 | 0 | $0 |
| Michael J Malecek | Chief Legal Officer | March 3, 2026 A | 80,000 | 0 | 0 | $0 |
| David A Ford | Chief People Officer | March 5, 2025 A | — | 0 | 0 | $0 |
| Carol D. Karp | Chief Regulatory Officer | March 5, 2025 A | 0 | 0 | 0 | $0 |
| Hideki Garren | Chief Medical Officer | Feb. 27, 2024 A | 0 | 0 | 0 | $0 |
| Radhika Tripuraneni | Chief Development Officer | Feb. 23, 2022 A | — | 0 | 0 | $0 |
| Arthur W Homan | Chief Legal Officer | June 21, 2018 A | 0 | 0 | 0 | $0 |
| Tara Nickerson | Chief Business Officer | Feb. 21, 2018 A | 2,000 | 0 | 0 | $0 |
| Sarah B. Noonberg | Chief Medical Officer | May 16, 2017 A | — | 0 | 0 | $0 |
| David B. Mcninch | Chief Commercial Officer | Feb. 24, 2016 A | — | 0 | 0 | $0 |
| Martin Koller | Chief Medical Officer | Feb. 24, 2016 A | 0 | 0 | 0 | $0 |
| John Randall Fawcett | Controller | Jan. 29, 2013 A | — | 0 | 0 | $0 |
| William H. Dunn Jr. | Director | May 15, 2026 A | — | 0 | 0 | $0 |
| Dennis J. Selkoe | Director | May 15, 2026 A | 2,845 | 0 | 0 | $0 |
| Shane Cooke | Director | May 15, 2026 A | 0 | 0 | 0 | $0 |
| Lars Ekman | Director | May 15, 2026 A | 243 | 0 | 0 | $0 |
| Daniel G Welch | Director | May 15, 2026 A | — | 0 | 0 | $0 |
| COLLIER RICHARD T | Director | May 15, 2026 A | 1,219 | 0 | 0 | $0 |
| Paula K Cobb | Director | May 14, 2025 A | — | 0 | 0 | $0 |
| Helen Kim | Director | May 14, 2025 A | — | 0 | 0 | $0 |
| Karl Anders Olof Harfstrand | Director | May 17, 2023 A | — | 0 | 0 | $0 |
| Sanjiv Patel | Director | May 18, 2022 A | — | 0 | 0 | $0 |
| William P Scully | 10% owner | Aug. 18, 2026 G | 750,000 | 7 | 0 | $3,420,500 |
| EcoR1 Capital, LLC | 10% owner | May 6, 2025 S | 5,304,596 | 0 | 0 | $0 |
| Christopher S Henney | — | July 12, 2021 M | 0 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×7 filings | May 29, 2025 | 0.00% | Amendment | Passive investment | SEC |
| Woodford Investment Management LLP, Neil Woodford | Oct. 9, 2015 | — | Initial filing | — | SEC |
| Elan Corporation, plc (2), Elan Science One Limited (2) | Dec. 28, 2012 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 26 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0.43% | 10,983 SH | Aug. 8, 2026 | Daily |
| IBRN · iShares Trust | 0.41% | 3,678 SH | Aug. 8, 2026 | Daily |
| LABU · Direxion Shares ETF Trust | 0.12% | 57,328 NS | April 30, 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.03% | 2,821 SH | Aug. 8, 2026 | Daily |
| IBB · iShares Trust | 0.03% | 340,612 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.03% | 82,462 NS | May 31, 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.02% | 28,906 SH | Aug. 8, 2026 | Daily |
| RSSL · Global X Funds | 0.02% | 19,314 NS | April 30, 2026 | N-PORT |
| IWO · iShares Trust | 0.01% | 245,578 SH | Aug. 8, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.01% | 177,323 NS | April 30, 2026 | N-PORT |
| IWM · iShares Trust | 0.01% | 1,140,824 SH | Aug. 8, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.01% | 34,579 SH | Aug. 8, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 255,810 SH | Aug. 8, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.01% | 15,431 SH | Aug. 8, 2026 | Daily |
| IWN · iShares Trust | 0.01% | 169,023 SH | Aug. 8, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.01% | 129,902 SH | Aug. 8, 2026 | Daily |
| DXUV · Dimensional ETF Trust | 0.00% | 1,214 NS | April 30, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 5,606 NS | April 30, 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 1,421 NS | May 31, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 18,613 NS | April 30, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 53,549 SH | Aug. 8, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 10,944 SH | Aug. 8, 2026 | Daily |
| DFUS · Dimensional ETF Trust | 0.00% | 6,950 NS | April 30, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 13,125 NS | April 30, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 479,945 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 3,260 SH | Aug. 8, 2026 | Daily |