OKUR OnKure Therapeutics, Inc. - Class A Common Stock
$4.33
Price · Aug 19, 2026
Fundamentals as of Aug 4, 2026
52W Range
$2–$5
66% of range
Analyst Rating
BUY
12 analysts
Price Target
$16
+258% upside
P/E (TTM)
-0.7
ROE
-88.6%
Net Profit Margin
-1733.7%
OKUR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$4.33
Market Cap
—
P/E (TTM)
-0.7
EPS (TTM)
$-4.40
Revenue (TTM)
$0
Div Yield
—
ROE
-88.6%
Debt/Equity
—
52W Range
$2 – $5
OKUR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$0
2024-12-31
→
2024-12-31
EPS
$-4.40
2020-12-31
→
2025-12-31
Free Cash Flow
$-52M
2021-12-31
→
2025-12-31
Margins
-1733.7%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
OKUR
Peer Median
P/E (TTM)
-0.7
1.2
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
OKUR
Peer Median
Operating Margin
-1833.7%
—
Net Profit Margin
-1733.7%
-1189.1%
ROA
-67.2%
-58.9%
ROE
-88.6%
-79.0%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
OKUR
Peer Median
Current Ratio
10.3
5.4
Quick Ratio
10.0
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
OKUR
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
OKUR
Peer Median
OKUR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
12 analysts
- Strong Buy 4 33.3%
- Buy 6 50.0%
- Hold 2 16.7%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
4 analysts · 2026-08-18
Median
$15.00
← Below all targets
$4.33
Low
$11.00
High
$21.00
Median target
$15.00
+246.4%
Mean target
$15.50
+258.0%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.11%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.31 | $-0.55 | 0.24% |
| March 31, 2026 | $-1.11 | $-0.76 | -0.35% |
| Dec. 31, 2025 | $-0.99 | $-1.18 | 0.18% |
| Sept. 30, 2025 | $-1.09 | $-1.22 | 0.13% |
| June 30, 2025 | $-1.14 | $-1.27 | 0.13% |
| March 31, 2025 | $-1.19 | $-1.49 | 0.30% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
| VYGR | $232M | -1.9 | -49.5% | -296.5% | -54.4% | — |
| CHRS | $172M | 1.0 | 59.8% | 398.4% | 185.8% | — |
| NKTX | $131M | -1.3 | — | — | -31.1% | — |
| CRBU | $151M | -1.0 | 11.7% | -1327.4% | -102.8% | — |
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | — |
| TNYA | $154M | -1.2 | — | — | -81.2% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| HUMA | — | — | — | — | — | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 13
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Revenue | · | $0 | |
| R&D Expense | $48M | $44M | |
| SG&A Expense | $15M | $11M | |
| Operating Expenses | $63M | $54M | |
| Operating Income | $-63M | $-54M | |
| Interest Income | $3M | $2M | |
| Income Tax | $0 | $0 | |
| Net Income | $-60M | $-53M | |
| EPS (Basic) | $-4.40 | $-15.28 | |
| EPS (Diluted) | $-4.40 | $-15.28 | |
| Shares (Basic) | 13,515,915 | 3,447,071 | |
| Shares (Diluted) | 13,515,915 | 3,447,071 | |
| EBITDA | $-63M | $-54M |
Balance Sheet 19
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Cash & Equivalents | $59M | $111M | |
| Prepaid Expense | $2M | $2M | |
| Current Assets | $61M | $113M | |
| PP&E (Net) | $618.0K | $1M | |
| PP&E (Gross) | $2M | $2M | |
| Accum. Depreciation | $1M | $1M | |
| Other Non-current Assets | $273.0K | $109.0K | |
| Total Assets | $62M | $115M | |
| Accounts Payable | $1M | $3M | |
| Accrued Liabilities | · | $7M | |
| Current Liabilities | $6M | $11M | |
| Capital Leases | $0 | $549.0K | |
| Other Non-current Liabilities | $12.0K | · | |
| Total Liabilities | $6M | $11M | |
| Paid-in Capital | $270M | $259M | |
| Retained Earnings | $-214M | $-155M | |
| AOCI | $0 | · | |
| Stockholders' Equity | $56M | $104M | |
| Liabilities + Equity | $62M | $115M |
Cash Flow 9
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| D&A | $447.0K | $459.0K | |
| Stock-based Comp | $12M | $5M | |
| Other Non-cash | $-4M | $-3M | |
| Operating Cash Flow | $-52M | $-51M | |
| CapEx | $46.0K | $52.0K | |
| Investing Cash Flow | $-46.0K | $16M | |
| Financing Cash Flow | $163.0K | $116M | |
| Net Change in Cash | $-52M | $81M | |
| Free Cash Flow | $-52M | $-51M |
Profitability 5
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Operating Margin | -1833.7% | · | |
| Net Margin | -1733.7% | · | |
| EBITDA Margin | -1820.6% | · | |
| ROA | -67.2% | -69.9% | |
| ROE | -88.6% | 337.4% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Current Ratio | 10.3 | 10.7 | |
| Quick Ratio | 10.0 | 10.5 |
Efficiency 1
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 |
Valuation (TTM) 4
| Metric | Trend | 2025 | 2024 |
|---|---|---|---|
| Revenue TTM | · | $0 | |
| Net Income TTM | $-60M | $-53M | |
| P/E | -0.7 | -0.6 | |
| Earnings Yield | -151.7% | -177.7% |
Income Statement 12
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $13M | $12M | $11M | $12M | $13M | $13M | $14M | $10M | $11M | $9M | $-7M | $14M | $14M | $11M | $10M | $10M | |
| SG&A Expense | $4M | $4M | $3M | $4M | $4M | $4M | $4M | $1M | $4M | $1M | $-14M | $7M | $7M | $5M | $4M | $4M | |
| Operating Expenses | $17M | $16M | $14M | $16M | $16M | $17M | $19M | $12M | $14M | $10M | $-21M | $21M | $21M | $16M | $15M | $14M | |
| Operating Income | $-17M | $-16M | $-14M | $-16M | $-16M | $-17M | $-19M | $-12M | $-14M | $-10M | $21M | $-21M | $-21M | $-16M | $-15M | $-14M | |
| Interest Income | $2M | $458.0K | $628.0K | $804.0K | $934.0K | $1M | $1M | $174.0K | $230.0K | $295.0K | · | · | · | · | · | · | |
| Other Non-op | · | · | · | · | · | · | · | $972.0K | $1M | $1M | · | $2M | $2M | $1M | $962.0K | $833.0K | |
| Net Income | $-15M | $-15M | $-14M | $-15M | $-15M | $-16M | $-17M | $-12M | $-14M | $-10M | $19M | $-19M | $-20M | $-15M | $-14M | $-13M | |
| EPS (Basic) | $-0.31 | $-1.11 | $-0.98 | $-1.09 | $-1.14 | $-1.19 | $96.46 | $-36.55 | $-44.82 | $-30.37 | $-117.48 | $-5.68 | $-0.65 | $-0.60 | $-0.56 | $-0.53 | |
| EPS (Diluted) | $-0.31 | $-1.11 | $-0.98 | $-1.09 | $-1.14 | $-1.19 | $96.46 | $-36.55 | $-44.82 | $-30.37 | $-117.48 | $-5.68 | $-0.65 | $-0.60 | $-0.56 | $-0.53 | |
| Shares (Basic) | 49,869,177 | 13,674,577 | -26,948,392 | 13,530,892 | 13,509,080 | 13,424,335 | 2,501,435 | 316,142 | 315,478 | 314,016 | -58,348,708 | 3,380,794 | 30,215,321 | 25,036,410 | -48,922,002 | 24,496,313 | |
| Shares (Diluted) | 49,869,177 | 13,674,577 | -26,948,392 | 13,530,892 | 13,509,080 | 13,424,335 | 2,501,435 | 316,142 | 315,478 | 314,016 | -58,348,708 | 3,380,794 | 30,215,321 | 25,036,410 | -48,922,002 | 24,496,313 | |
| EBITDA | $-17M | $-16M | · | $-15M | $-16M | $-17M | · | $-5M | $-6M | $-10M | · | $-21M | $-21M | $-16M | · | $-14M |
Balance Sheet 22
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $167M | $192M | $59M | $70M | $83M | $97M | $111M | $61M | $36M | $20M | $30M | $12M | $9M | $30M | $20M | $62M | |
| Short-term Investments | · | · | · | · | · | · | · | $16M | $41M | $62M | · | $114M | $134M | $63M | $81M | $54M | |
| Prepaid Expense | $1M | $5M | $2M | $1M | $1M | $2M | $2M | $331.0K | $1M | $1M | $4M | $3M | $4M | $3M | $5M | $5M | |
| Current Assets | $178M | $197M | $61M | $72M | $85M | $98M | $113M | $77M | $78M | $84M | $34M | $129M | $146M | $97M | $106M | $121M | |
| PP&E (Net) | $435.0K | $519.0K | $618.0K | $720.0K | $821.0K | $925.0K | $1M | $59.0K | $81.0K | $102.0K | $1M | $529.0K | $554.0K | $581.0K | $453.0K | $241.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | · | $2M | · | · | · | $555.0K | · | |
| Accum. Depreciation | $2M | $2M | $1M | $1M | $1M | $1M | $1M | · | · | · | $665.0K | · | · | · | $102.0K | · | |
| Other Non-current Assets | $401.0K | $405.0K | $273.0K | $104.0K | $116.0K | $109.0K | $109.0K | $147.0K | $153.0K | $64.0K | $58.0K | $81.0K | $79.0K | $81.0K | $84.0K | $79.0K | |
| Total Assets | $179M | $199M | $62M | $73M | $86M | $100M | $115M | $78M | $79M | $85M | $36M | $130M | $148M | $99M | $108M | $123M | |
| Accounts Payable | $2M | $11M | $1M | $1M | $2M | $2M | $3M | $237.0K | $64.0K | $676.0K | $3M | $2M | $2M | $2M | $2M | $2M | |
| Accrued Liabilities | · | · | · | · | $5M | $6M | · | $725.0K | $953.0K | $2M | $4M | $11M | $12M | $8M | $5M | $7M | |
| Current Liabilities | $7M | $14M | $6M | $6M | $8M | $9M | $11M | $3M | $1M | $3M | $7M | $14M | $14M | $10M | $7M | $9M | |
| Capital Leases | $590.0K | $0 | · | $120.0K | $267.0K | $409.0K | $549.0K | $379.0K | $492.0K | $576.0K | $466.0K | $812.0K | $897.0K | $979.0K | $1M | $943.0K | |
| Other Non-current Liabilities | $12.0K | $12.0K | $12.0K | $40.0K | $40.0K | $40.0K | · | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $7M | $14M | $6M | $6M | $8M | $9M | $11M | $4M | $2M | $3M | $8M | $15M | $16M | $12M | $8M | $10M | |
| Common Stock | · | · | · | · | · | · | · | $0 | $3.0K | $3.0K | · | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $417M | $414M | $270M | $267M | $264M | $261M | $259M | $310M | $309M | $308M | $209.0K | $305M | $304M | $239M | $237M | $235M | |
| Retained Earnings | $-245M | $-229M | $-214M | $-201M | $-186M | $-171M | $-155M | $-236M | $-232M | $-227M | $-102M | $-191M | $-171M | $-152M | $-137M | $-123M | |
| AOCI | $-13.0K | · | · | · | · | · | · | $2.0K | $-13.0K | $-12.0K | · | $-21.0K | $-31.0K | $12.0K | $-43.0K | $-26.0K | |
| Stockholders' Equity | $172M | $184M | $56M | $66M | $78M | $91M | $104M | $74M | $77M | $81M | $-102M | $115M | $133M | $87M | $100M | $112M | |
| Liabilities + Equity | $179M | $199M | $62M | $73M | $86M | $100M | $115M | $78M | $79M | $85M | $36M | $130M | $148M | $99M | $108M | $123M | |
| Shares Outstanding | · | · | · | · | · | · | · | 3,343,525 | 33,420,808 | 33,420,808 | · | 33,872,166 | 33,800,788 | 25,107,430 | 24,699,553 | 24,529,646 |
Cash Flow 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $87.0K | $104.0K | $104.0K | $108.0K | $117.0K | $118.0K | $116.0K | $114.0K | $115.0K | $114.0K | $291.0K | $43.0K | $42.0K | $41.0K | $25.0K | $22.0K | |
| Stock-based Comp | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $-70.0K | $842.0K | $107.0K | $-4M | $1M | $1M | $1M | $1M | $990.0K | |
| Other Non-cash | · | $-665.0K | · | · | · | $-943.0K | · | · | · | $-14M | · | · | · | $5M | · | · | |
| Operating Cash Flow | $-10M | $-13M | $-12M | $-13M | $-13M | $-14M | $-23M | $58.0K | $4M | $-11M | $9M | $-19M | $-16M | $-9M | $-16M | $-11M | |
| CapEx | $3.0K | $5.0K | $9.0K | $6.0K | $13.0K | $18.0K | $15.0K | $35.0K | $10.0K | $9.0K | $50.0K | $19.0K | $5.0K | $172.0K | $250.0K | $28.0K | |
| Investing Cash Flow | $-10M | $-5.0K | $-9.0K | $-6.0K | $-13.0K | $-18.0K | $16M | $-36M | $-14M | $-9.0K | $29M | $21M | $-69M | $19M | $-27M | $-45M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | · | · | · | $1M | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $1M | · | · | |
| Financing Cash Flow | $-5M | $146M | $240.0K | $0 | $0 | $-77.0K | $110M | $6M | $6M | $10.0K | $-12M | $173.0K | $64M | $1M | $325.0K | $97.0K | |
| Net Change in Cash | $-26M | $133M | $-11M | $-13M | $-13M | $-14M | $103M | $-30M | $-4M | $-11M | $27M | $3M | $-21M | $10M | $-42M | $-56M | |
| Free Cash Flow | · | $-13M | · | · | · | $-14M | · | · | · | · | · | · | · | $-9M | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1088.2% | -3409.4% | · | -1932.8% | -1747.8% | · | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -988.2% | -3309.4% | · | -1832.8% | -1647.8% | · | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -1088.2% | -3386.7% | · | -1919.3% | -1735.2% | · | · | · | · | · | · | · | · | · | · | · | |
| ROA | -11.6% | -10.2% | · | -19.5% | -18.7% | -17.3% | · | -3.5% | -4.7% | -9.2% | · | -15.2% | -13.9% | -12.4% | · | -9.1% | |
| ROE | -12.3% | -11.0% | · | -20.9% | -19.9% | -18.5% | · | -3.9% | -5.1% | -10.0% | · | -16.9% | -15.2% | -13.6% | · | -9.7% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 26.7 | 13.8 | · | 11.4 | 11.1 | 11.2 | · | 23.7 | 57.9 | 29.8 | · | 9.5 | 10.7 | 9.3 | · | 12.8 | |
| Quick Ratio | 25.1 | 13.4 | · | 11.3 | 11.0 | 11.0 | · | 23.6 | 56.9 | 29.4 | · | 9.3 | 10.4 | 8.9 | · | 12.3 |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 8
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-59M | $-59M | · | $-63M | $-60M | $-59M | · | $-54M | $-62M | $-63M | · | $-67M | $-60M | $-53M | · | $-51M | |
| Market Cap | · | · | · | · | · | · | · | $57M | $505M | $555M | · | $2.58B | $2.22B | $1.50B | · | $822M | |
| P/E | -1.2 | -0.9 | · | -0.1 | -0.0 | -0.0 | · | -0.1 | -0.2 | -0.4 | · | -10.2 | -28.8 | -27.7 | · | -16.1 | |
| P/B | · | · | · | · | · | · | · | 0.8 | 6.6 | 6.8 | · | 22.4 | 16.7 | 17.2 | · | 7.3 | |
| P / Tangible Book | · | · | · | · | · | · | · | 0.8 | 6.6 | 6.8 | · | 22.4 | 16.7 | 17.2 | · | 7.3 | |
| P / Cash Flow | · | · | · | · | · | · | · | · | · | -26.4 | · | · | · | -165.9 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -162.8 | · | · | |
| Earnings Yield | -80.0% | -109.4% | · | -1453.5% | -3502.1% | -2626.3% | · | -690.7% | -539.9% | -224.7% | · | -9.8% | -3.5% | -3.6% | · | -6.2% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | — | $0 | — | — | — |
| Operating Margin % | -1833.7% | — | — | — | — |
| Net Income | $-60M | $-53M | $-35M | $-52M | $-40M |
| Diluted EPS | $-4.40 | $-15.28 | $-124.41 | $-2.12 | $-2.19 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 10.3 | 10.7 | — | 14.9 | 24.8 |
| Quick Ratio | 10.0 | 10.5 | — | 14.2 | 23.8 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-52M | $-51M | — | $-48M | $-38M |
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Institutional owners (13F) 78 filers · $148.9M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 34 (+19 vs prior Q) | 7 (0 vs prior Q) | 14 (+1 vs prior Q) | 13 (+1 vs prior Q) | +3.3M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $18,232,398 | 3,998,333 | 12.25% | Shares |
| BVF INC/IL | $14,755,148 | 3,235,778 | 9.91% | Shares |
| ACORN CAPITAL ADVISORS, LLC | $12,948,913 | 2,839,674 | 8.70% | Shares |
| StepStone Group LP | $11,014,934 | 2,660,612 | 7.40% | Shares |
| ADAR1 Capital Management, LLC | $10,208,399 | 2,238,684 | 6.86% | Shares |
| Vivo Capital, LLC | $8,790,358 | 1,927,710 | 5.91% | Shares |
| Vestal Point Capital, LP | $8,325,187 | 1,825,699 | 5.59% | Shares |
| Trails Edge Capital Partners, LP | $6,559,359 | 1,438,456 | 4.41% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $6,552,898 | 1,437,039 | 4.40% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5,493,975 | 1,204,819 | 3.69% | Shares |
| CITADEL ADVISORS LLC | $5,412,934 | 1,187,047 | 3.64% | Shares |
| Sio Capital Management, LLC | $4,920,080 | 1,078,965 | 3.31% | Shares |
| Prosight Management, LP | $4,464,204 | 978,992 | 3.00% | Shares |
| Logos Global Management LP | $4,395,179 | 963,855 | 2.95% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $2,788,902 | 611,596 | 1.87% | Shares |
| NEA Management Company, LLC | $2,182,179 | 478,548 | 1.47% | Shares |
| STATE STREET CORP | $2,114,299 | 463,662 | 1.42% | Shares |
| Ensign Peak Advisors, Inc | $1,968,237 | 431,631 | 1.32% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,635,845 | 358,738 | 1.10% | Shares |
| Sofinnova Investments, Inc. | $1,466,916 | 321,692 | 0.99% | Shares |
| Carlyle Group Inc. | $1,230,721 | 269,895 | 0.83% | Shares |
| Seven Fleet Capital Management LP | $1,098,791 | 240,963 | 0.74% | Shares |
| Affinity Asset Advisors, LLC | $1,098,791 | 240,963 | 0.74% | Shares |
| DV EQUITIES, LLC | $1,098,791 | 240,963 | 0.74% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $810,613 | 177,766 | 0.54% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $753,207 | 165,177 | 0.51% | Shares |
| Rosalind Advisors, Inc. | $684,000 | 150,000 | 0.46% | Shares |
| Stonepine Capital Management, LLC | $595,919 | 130,684 | 0.40% | Shares |
| KOTLER KEVIN | $573,304 | 197,691 | 0.39% | Shares |
| Longaeva Partners L.P. | $549,398 | 120,482 | 0.37% | Shares |
| TWO SIGMA INVESTMENTS, LP | $496,447 | 108,870 | 0.33% | Shares |
| BANK OF AMERICA CORP /DE/ | $484,819 | 106,320 | 0.33% | Shares |
| CANTOR FITZGERALD, L. P. | $456,064 | 100,014 | 0.31% | Shares |
| UBS Group AG | $454,194 | 99,604 | 0.31% | Shares |
| Rangeley Capital, LLC | $433,200 | 95,000 | 0.29% | Shares |
| Aisling Capital Management LP | $404,048 | 88,607 | 0.27% | Shares |
| Walleye Capital LLC | $324,230 | 71,103 | 0.22% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $290,198 | 63,640 | 0.19% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $229,336 | 50,293 | 0.15% | Shares |
| Shay Capital LLC | $228,000 | 50,000 | 0.15% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $221,766 | 48,633 | 0.15% | Shares |
| PRELUDE CAPITAL MANAGEMENT, LLC | $212,916 | 46,692 | 0.14% | Shares |
| Aldebaran Capital, LLC | $181,803 | 39,869 | 0.12% | Shares |
| Nuveen, LLC | $161,433 | 35,402 | 0.11% | Shares |
| Verdad Advisers, LP | $130,690 | 28,660 | 0.09% | Shares |
| Bank of New York Mellon Corp | $119,705 | 26,251 | 0.08% | Shares |
| DEUTSCHE BANK AG\ | $116,572 | 25,564 | 0.08% | Shares |
| AMERICAN CENTURY COMPANIES INC | $105,231 | 23,077 | 0.07% | Shares |
| WELLS FARGO & COMPANY/MN | $100,097 | 21,951 | 0.07% | Shares |
| RHUMBLINE ADVISERS | $95,736 | 20,996 | 0.06% | Shares |
| Jump Financial, LLC | $93,024 | 20,400 | 0.06% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $90,694 | 19,889 | 0.06% | Shares |
| MARSHALL WACE, LLP | $83,744 | 18,365 | 0.06% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $82,536 | 18,100 | 0.06% | Shares |
| XTX Topco Ltd | $77,383 | 16,970 | 0.05% | Shares |
| TWO SIGMA ADVISERS, LP | $77,163 | 26,608 | 0.05% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $55,035 | 12,069 | 0.04% | Shares |
| Y-Intercept (Hong Kong) Ltd | $51,473 | 11,288 | 0.03% | Shares |
| CITIGROUP INC | $48,687 | 10,677 | 0.03% | Shares |
| Invesco Ltd. | $47,657 | 10,451 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $47,073 | 10,323 | 0.03% | Shares |
| MORGAN STANLEY | $29,900 | 6,557 | 0.02% | Shares |
| BARCLAYS PLC | $20,520 | 4,500 | 0.01% | Shares |
| NORTHERN TRUST CORP | $18,778 | 4,118 | 0.01% | Shares |
| Legal & General Group Plc | $11,651 | 2,555 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $10,848 | 2,379 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $9,557 | 2,096 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $7,346 | 1,611 | 0.00% | Shares |
| BlackRock, Inc. | $6,644 | 1,457 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $4,000 | 966 | 0.00% | Shares |
| Sterling Capital Management LLC | $2,408 | 528 | 0.00% | Shares |
| VANGUARD GROUP INC | $2,161 | 745 | 0.00% | Shares |
| TRUST CO OF TOLEDO NA /OH/ | $620 | 136 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $410 | 90 | 0.00% | Shares |
| FMR LLC | $406 | 89 | 0.00% | Shares |
| JPMORGAN CHASE & CO | $203 | 45 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $98 | 21,481 | 0.00% | Shares |
| T. Rowe Price Investment Management, Inc. | $70 | 15,335 | 0.00% | Shares |
Company insiders 28 insiders · 6 officers · 9 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Gregory J. Flesher | President and CEO | Dec. 9, 2022 A | 109,600 | 0 | 0 | $0 |
| Michael Cruse | Chief Operating Officer | Dec. 9, 2022 A | 13,697 | 0 | 0 | $0 |
| Ashley Hall | Chief Development Officer | Aug. 28, 2023 M | 39,600 | 0 | 0 | $0 |
| Jennifer Lam | VP of Finance & Administration | Dec. 9, 2022 A | — | 0 | 0 | $0 |
| Alejandro Dorenbaum | Chief Medical Officer | Dec. 9, 2022 A | 30,000 | 0 | 0 | $0 |
| Wendy S. Johnson | Chief Development Officer | July 14, 2021 S | 0 | 0 | 0 | $0 |
| Roshawn A. Blunt | Director | June 6, 2023 A | — | 0 | 0 | $0 |
| Bali Muralidhar | Director | June 6, 2023 A | 2,073,957 | 0 | 0 | $0 |
| Niall O'Donnell, Ph.D. | Director | June 6, 2023 A | 2,188,713 | 0 | 0 | $0 |
| Eric M Dube | Director | June 6, 2023 A | — | 0 | 0 | $0 |
| Stacey Denenberg Seltzer | Director | June 6, 2023 A | — | 0 | 0 | $0 |
| Paul W. Hoelscher | Director | June 6, 2023 A | — | 0 | 0 | $0 |
| Lon Cardon | Director | April 8, 2021 A | — | 0 | 0 | $0 |
| Kenneth Harrison Ph.D. | Director | April 8, 2021 A | — | 0 | 0 | $0 |
| Novo Holdings A/S | 10% owner | June 23, 2023 S | 3,330,337 | 0 | 0 | $0 |
| Dylan Hartley | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Andrew John Phillips | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Valerie Malyvanh Jansen | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Samuel Agresta | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Jason A. Leverone | — | Aug. 7, 2026 A | 18,802 | 0 | 1 | $-1,333 |
| Michael R Carruthers | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Isaac Manke | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Nicholas A Saccomano | — | Aug. 7, 2026 A | 11,247 | 0 | 1 | $-378 |
| Liam Ratcliffe | — | Aug. 7, 2026 A | — | 0 | 0 | $0 |
| Edward T. Mathers | — | Aug. 7, 2026 A | 15,310 | 0 | 0 | $0 |
| Michael G Grey | — | Aug. 7, 2026 A | 0 | 0 | 0 | $0 |
| Leonard Braden Michael | — | Oct. 7, 2024 J | 102,076 | 0 | 0 | $0 |
| Vineet R. Jindal | — | Dec. 10, 2021 A | 36,600 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 10 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| AI Biotechnology LLC, Access Industries Holdings LLC, Access Industries Management, LLC, Len Blavatnik | April 7, 2026 | 19.99% | Initial filing | — | SEC |
| ACORN BIOVENTURES, L.P., ACORN CAPITAL ADVISORS GP, LLC, Anders Hove, ACORN BIOVENTURES 2, L.P., Acorn Capital Advisors GP 2, LLC ×2 filings | May 30, 2025 | 22.10% | Amendment | — | SEC |
| RiverVest Venture Fund III, L.P., RiverVest Venture Fund III (Ohio), L.P., RiverVest Venture Partners III (Ohio), LLC, RiverVest Venture Partners III, L.P., RiverVest Venture Partners III, LLC, RiverVest Venture Fund IV, L.P., RiverVest Venture Partners IV, L.P., RiverVest Venture Partners IV, LLC, John P. McKearn, Ph.D., Jay Schmelter, Thomas C. Melzer, Niall O'Donnell, Ph.D. | Jan. 21, 2025 | 1.55% | Amendment | — | SEC |
| Oct. 8, 2024 | — | Initial filing | — | SEC | |
| New Enterprise Associates 15, L.P., NEA Partners 15, L.P., NEA 15 GP, LLC, Forest Baskett, Anthony A. Florence, Jr., Mohamad H. Makhzoumi, Scott D. Sandell ×2 filings | May 8, 2024 | — | Initial filing | — | SEC |
| TANG CAPITAL PARTNERS, LP, TANG CAPITAL MANAGEMENT, LLC, KEVIN TANG, Concentra Biosciences, LLC | Dec. 26, 2023 | — | Initial filing | — | SEC |
| Novo Holdings A/S ×5 filings | Dec. 15, 2023 | — | Initial filing | — | SEC |
| Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person | May 30, 2023 | — | Initial filing | — | SEC |
| Abingworth LLP, Abingworth Bioventures 8, LP | April 20, 2021 | — | Initial filing | Passive investment | SEC |
| Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person | April 19, 2021 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 5 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0.02% | 87,541 SH | Aug. 8, 2026 | Daily |
| IWN · iShares Trust | 0.01% | 225,561 SH | Aug. 8, 2026 | Daily |
| IWM · iShares Trust | 0.00% | 557,532 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.00% | 8,831 NS | May 31, 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0.00% | 21,147 NS | April 30, 2026 | N-PORT |