PTCT PTC Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · Voir sur SEC EDGAR ↗
$72,62
Prix · Aoû 19, 2026
Données fondamentales au Jul 30, 2026

À propos de PTC Therapeutics, Inc. - Common Stock Présentation de l'entreprise depuis Wikipedia

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

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PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

In September 2009, PTC entered into an agreement with Roche for the development of orally bioavailable small molecules for central nervous system diseases. PTC acquired the Bio-e platform in 2019.

Products

In 2017, PTC acquired Emflaza (deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together, the two products generated revenues of 174 million dollars and 260 million dollars in 2017 and 2018 respectively.

PTC has the commercialization rights for WAYLIVRA (volanesorsen) in Latin America.

In 2018, PTC acquired Agilis Biotherapeutics and a gene therapy candidate, GT-AADC, with its compelling clinical data in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare CNS disorder arising from reductions in the enzyme AADC that result from mutations in the dopa decarboxylase (DDC) gene. As of 2024, the AAV based treatment for AADC deficiency has been approved by the FDA and commercialized in the United States as Kebilidi. It is the first FDA-approved gene therapy treatment for AADC deficiency. This same product was granted EMA approval for use in the European Union under the name Upstaza.

Pipeline

In 2020, PTC acquired Censa Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of CNSA-001 (sepiapterin), a clinical-stage investigational therapy for orphan metabolic diseases, including phenylketonuria (PKU) and other diseases associated with defects in the tetrahydrobiopterin (BH4) biochemical pathways diagnosed at birth.

In 2020, PTC announced the FDA approval of Evrysdi (risdiplam) for the treatment of spinal muscular atrophy (SMA) in adults and children 2 months and older.

In 2024, Novartis has committed $1 billion upfront in a licensing deal with PTC Therapeutics for an experimental treatment for Huntington’s disease, with the potential for an additional $1.9 billion tied to achieving specific development, regulatory, and commercial milestones. PTC Therapeutics’ therapy, known as PTC518, is an oral medication designed to reduce the production of the mutant protein linked to the genetic mutation responsible for the disease. This mutant protein is believed to contribute to neuronal death, driving disease progression. In June, interim data from a Phase 2 trial indicated that PTC518 successfully lowered levels of the mutant protein in both blood and cerebrospinal fluid.

Source : Wikipedia (Anglais), CC BY-SA 4.0 · Voir sur Wikipedia ↗

Wikidata ↗

PTCT Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines

Prix
$72.62
Capitalisation Boursière
$5.92B
P/E (TTM)
9.3
BPA (TTM)
$7.78
Revenus (TTM)
$1.73B
Rendement div.
ROE
-331.5%
Dette/Capitaux propres
-1.4
Fourchette 52 semaines
$48 – $91

PTCT Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue

Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA

Revenus et bénéfice net $1.73B
10-point trend, +1992.6%
2016-12-31 2025-12-31
BPA $7.78
7-point trend, +282.2%
2019-12-31 2025-12-31
Flux de trésorerie libre $702M
9-point trend, +766.7%
2016-12-31 2025-12-31
Marges 39.4%

Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs
P/E (TTM)
5-point trend, +282.1%
9.3
37.2
P/S (TTM)
5-point trend, -68.0%
3.4
9.9
P/B
5-point trend, -441.5%
-28.8
8.3
EV / EBITDA
5-point trend, +156.1%
4.7
Price / FCF (Cours / FCF)
5-point trend, +143.9%
8.4

Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs
Operating Margin (Marge d'exploitation)
5-point trend, +144.2%
50.1%
Net Profit Margin (Marge nette)
5-point trend, +134.3%
39.4%
-15.1%
ROA
5-point trend, +229.7%
29.7%
-23.3%
ROE
5-point trend, -275.6%
-331.5%
-30.6%
ROIC
5-point trend, +1860.3%
1044.7%

Santé financière Dette, liquidité, solvabilité — solidité du bilan

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs
Debt / Equity (Dette / Capitaux propres)
5-point trend, -317.7%
-1.4
Current Ratio (Ratio de liquidité)
5-point trend, -47.1%
2.3
6.3
Quick Ratio (Ratio de liquidité réduite)
5-point trend, -48.1%
2.2

Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
5-point trend, +221.3%
114.5%
Revenue CAGR 3Y (CAGR du chiffre d'affaires 3 ans)
5-point trend, +221.3%
35.3%
Revenue CAGR 5Y (CAGR du chiffre d'affaires 5 ans)
5-point trend, +221.3%
35.4%

Indicateurs par action BPA, valeur comptable par action, flux de trésorerie par action, dividende par action

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs
EPS (Diluted) (BPA (Dilué))
5-point trend, +204.7%
$7.78

Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances

Métrique
Tendance sur 5 ans
PTCT
Médiane des pairs

PTCT Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse

ACHAT 21 analystes
  • Achat fort 6 28,6%
  • Achat 11 52,4%
  • Conserver 3 14,3%
  • Vente 1 4,8%
  • Vente forte 0 0,0%

Objectif de cours à 12 mois

14 analystes · 2026-08-13
Objectif médian $98.00 +34,9%
Objectif moyen $97.86 +34,8%

Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats

Surprise Moyenne
1.9%
Période EPS Actual BPA est. Surprise
30 juin 2026 $0.92 $0.43 0.49%
31 mars 2026 $-0.03 $-0.48 0.45%
31 décembre 2025 $-1.67 $0.04 -1.7%
30 septembre 2025 $0.20 $-1.40 1.6%
30 juin 2025 $-0.83 $-1.08 0.25%
31 mars 2025 $10.04 $-0.22 10.3%

Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur

Ticker Capitalisation Boursière P/E Revenus Année/Année Marge Nette ROE Marge Brute
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
MIRM $4.10B -168.1 54.7% -4.5% -8.2%
COGT $5.72B -16.4 -83.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
ERAS $1.06B -8.5 -35.7%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DYN $3.23B -5.6 -57.8%
PBLS
CELC $4.81B -26.3 -244.3%

Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie

Compte de résultat 15
Données annuelles Compte de résultat pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Cost of Revenue 5-point trend, +12135000.00 · · · · · · $12M $13M $5M $0 $0 ·
R&D Expense 12-point trend, +470.2% $455M $534M $667M $651M $541M $478M $257M $172M $117M $118M $122M $80M
SG&A Expense 12-point trend, +674.5% $347M $301M $333M $326M $286M $245M $203M $154M $121M $97M $82M $45M
Operating Expenses 12-point trend, +592.9% $864M $1.11B $1.38B $1.15B $913M $813M $548M $380M $259M $215M $204M $125M
Operating Income 12-point trend, +972.1% $867M $-303M $-440M $-447M $-374M $-432M $-241M $-116M $-64M $-132M $-167M $-99M
Other Non-op 12-point trend, -8391.1% $-18M $7M $10M $-49M $-58M $85M $14M $129.0K $-1M $-1M $-465.0K $-213.0K
Pretax Income 12-point trend, +807.6% $697M $-363M $-696M $-587M $-518M $-403M $-240M $-128M $-78M $-142M $-170M $-98M
Income Tax 12-point trend, +397.8% $14M $176.0K $-70M $-28M $6M $35M $12M $-29.0K $1M $569.0K $485.0K $-5M
Net Income 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
EPS (Basic) 10-point trend, +388.9% $8.58 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-2.75 $-2.02 · · $-2.97
EPS (Diluted) 8-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 · · · · $-2.97
Shares (Basic) 8-point trend, +152.0% 79,534,290 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
Shares (Diluted) 8-point trend, +179.8% 88,311,494 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
EBITDA 11-point trend, +1011.1% $906M $-227M $-203M · $-310M $-388M $-209M $-90M $-47M $-132M $-167M $-99M
Bilan 27
Données annuelles Bilan pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +1879.3% $985M $780M $594M $280M $190M $209M $288M $169M $112M $58M $58M $50M
Short-term Investments 12-point trend, +261.9% $961M $360M $283M $131M $584M $895M $399M $58M $79M $173M $281M $265M
Receivables 12-point trend, +3986.0% $182M $159M $161M $156M $110M $70M $56M $68M $40M $25M $11M $4M
Inventory 10-point trend, +79647000.00 $80M $23M $31M $22M $16M $19M $19M $16M $11M $0 · ·
Prepaid Expense 12-point trend, +1632.5% $67M $44M $150M $106M $55M $39M $18M $9M $7M $5M $6M $4M
Current Assets 12-point trend, +602.8% $2.27B $1.37B $1.22B $694M $954M $1.23B $779M $321M $249M $261M $356M $324M
PP&E (Net) 12-point trend, +504.6% $55M $61M $87M $73M $53M $34M $22M $13M $8M $7M $9M $9M
PP&E (Gross) 12-point trend, +200.4% $102M $94M $138M $110M $80M $52M $33M $20M $41M $38M $37M $34M
Accum. Depreciation 12-point trend, +88.6% $47M $33M $51M $37M $27M $18M $12M $7M $33M $31M $28M $25M
Goodwill 9-point trend, +82341000.00 $82M $82M $82M $82M $82M $82M $82M $82M $0 · · ·
Intangibles 10-point trend, +388753000.00 $389M $119M $379M $706M $725M $715M $710M $701M $133M $0 · ·
Total Assets 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Accounts Payable 12-point trend, +1001.9% $45M $17M $6M $27M $23M $19M $10M $6M $15M $6M $6M $4M
Current Liabilities 12-point trend, +2882.1% $968M $581M $603M $406M $509M $277M $236M $167M $82M $50M $45M $32M
Capital Leases 7-point trend, +937.7% $94M $75M $98M $101M $74M $79M $9M · · · · ·
Deferred Tax 7-point trend, +55905000.00 · · $56M $103M $137M $137M $131M $122M $0 · · ·
Other Non-current Liabilities 11-point trend, +501.8% $14M $21M $141.0K $3M · $1M $141.0K $58.0K $243.0K $335.0K $2M $2M
Total Liabilities 12-point trend, +8832.1% $3.10B $2.80B $2.71B $2.05B $1.94B $1.73B $1.03B $768M $235M $150M $139M $35M
Long-term Debt 4-point trend, +197.6% · · · · $431M · $314M $153M $145M · · ·
Total Debt 10-point trend, +203.0% $287M $285M $284M · $431M $309M $314M $153M $145M $98M $95M ·
Common Stock 12-point trend, +142.4% $80.0K $77.0K $75.0K $72.0K $71.0K $70.0K $62.0K $51.0K $42.0K $34.0K $34.0K $33.0K
Paid-in Capital 12-point trend, +280.8% $2.75B $2.57B $2.47B $2.31B $2.12B $2.17B $1.80B $1.29B $967M $856M $820M $722M
Retained Earnings 12-point trend, -601.5% $-2.96B $-3.65B $-3.28B $-2.66B $-2.10B $-1.63B $-1.19B $-939M $-814M $-735M $-593M $-423M
AOCI 12-point trend, +1524.8% $11M $-26M $-1M $5M $-24M $-61M $-11M $1M $4M $-1M $-1M $-737.0K
Stockholders' Equity 12-point trend, -168.8% $-205M $-1.10B $-819M $-347M $1M $482M $594M $351M $156M $120M $226M $298M
Liabilities + Equity 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Shares Outstanding 12-point trend, +147.7% 81,474,366 77,704,188 75,708,889 73,104,692 70,828,226 69,718,096 61,935,870 50,606,147 41,612,395 34,169,410 33,916,559 32,898,392
Flux de trésorerie 16
Données annuelles Flux de trésorerie pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
D&A 11-point trend, +1249.6% $39M $76M $237M $129M $64M $43M $32M $26M $18M $3M $3M ·
Stock-based Comp 12-point trend, +286.1% $75M $75M $102M $110M $104M $70M $42M $33M $31M $35M $34M $19M
Deferred Tax 12-point trend, -3000.00 $-3.0K $-56M $-47M $-34M $377.0K $6M $9M $0 $199.0K $-199.0K $0 $0
Amort. of Intangibles 11-point trend, +24742000.00 $25M $61M $223M $117M $55M $37M $28M $23M $15M $0 $0 ·
Restructuring · · · · · · · · $0 · · ·
Other Non-cash 8-point trend, -513.8% $-85M $161M $177M · $105M $124M $70M $41M $20M · · ·
Operating Cash Flow 12-point trend, +1341.7% $711M $-108M $-158M $-357M $-251M $-194M $-99M $-28M $-10M $-104M $-124M $-57M
CapEx 12-point trend, +90.0% $9M $7M $28M $32M $28M $18M $14M $7M $3M $2M $3M $5M
Investing Cash Flow 12-point trend, -493.8% $-862M $44M $-177M $290M $219M $-562M $-387M $-43M $13M $104M $-21M $-145M
Net Debt Issued 2-point trend, +100.0% · · · · · · · · · $0 · $-49.0K
Stock Issued 7-point trend, -88.1% · · · · · $28M $324M $118M $0 $0 $0 $236M
Net Stock Activity 5-point trend, -88.1% · · · · · $28M $324M $118M · $0 · $236M
Financing Cash Flow 12-point trend, +39.6% $331M $256M $646M $168M $21M $669M $613M $132M $44M $968.0K $154M $237M
Net Change in Cash 12-point trend, +491.3% $203M $185M $314M $99M $-19M $-79M $126M $58M $53M $299.0K $8M $34M
Taxes Paid 12-point trend, +36854000.00 $37M $18M $14M $5M $8M $26M $2M $2M $1M $943.0K $111.0K $0
Free Cash Flow 11-point trend, +1233.9% $702M $-114M $-187M · $-280M $-212M $-112M $-35M $-13M $-105M $-127M $-62M
Rentabilité 7
Données annuelles Rentabilité pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +112.7% 50.1% -37.5% -46.9% · -69.5% -113.4% -78.6% -43.7% -33.1% -159.7% -454.6% -393.8%
Net Margin 11-point trend, +110.6% 39.4% -45.0% -66.8% · -97.3% -115.1% -82.0% -48.4% -40.6% -171.8% -463.6% -371.4%
Pretax Margin 11-point trend, +110.3% 40.2% -45.0% -74.2% · -96.2% -105.8% -78.2% -48.4% -40.0% -171.1% -462.3% -390.0%
EBITDA Margin 11-point trend, +113.3% 52.3% -28.1% -21.6% · -57.6% -102.0% -68.1% -33.8% -24.0% -159.7% -454.6% -393.8%
ROA 11-point trend, +176.7% 29.7% -20.2% -34.8% · -25.3% -22.9% -18.3% -17.0% -23.9% -44.8% -48.6% -38.6%
ROE 11-point trend, -669.1% -331.5% 33.8% 84.1% · -985.1% -88.3% -40.0% -34.8% -57.2% -82.2% -65.0% -43.1%
ROIC 11-point trend, +3393.6% 1044.7% 37.2% 74.0% · -87.4% -59.4% -27.8% -23.0% -21.7% -60.9% -52.3% -31.7%
Liquidité et Solvabilité 4
Données annuelles Liquidité et Solvabilité pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -76.4% 2.3 2.4 2.0 · 1.9 4.4 3.3 1.9 3.0 5.3 7.8 10.0
Quick Ratio 11-point trend, -77.7% 2.2 2.2 1.7 · 1.7 4.2 3.1 1.8 2.8 5.2 7.7 9.8
Debt / Equity 10-point trend, -433.5% -1.4 -0.3 -0.3 · 300.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
LT Debt / Equity 9-point trend, -162.1% · -0.3 -0.3 · 196.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
Efficacité 3
Données annuelles Efficacité pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +622.2% 0.8 0.4 0.5 · 0.3 0.2 0.2 0.4 0.6 0.3 0.1 0.1
Inventory Turnover 2-point trend, -19.5% · · · · · · 0.7 · 0.9 · · ·
Receivables Turnover 11-point trend, +8.9% 10.2 5.1 5.9 · 6.0 6.1 5.0 4.9 6.0 4.6 4.7 9.3
Par action 5
Données annuelles Par action pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, -127.8% $-2.52 $-14.13 $-10.81 · $0.02 $6.91 $9.60 $6.93 $3.76 $3.50 $6.66 $9.07
Revenue / Share 5-point trend, +2350.3% $19.60 $10.50 $12.53 · $7.64 · · · · · · $0.80
Cash Flow / Share 5-point trend, +543.8% $8.05 $-1.40 $-2.12 · $-3.57 · · · · · · $-1.81
Cash / Share 11-point trend, +699.2% $12.09 $10.03 $7.85 · $2.68 $3.00 $4.65 $3.35 $2.69 $1.71 $1.71 $1.51
EPS (TTM) 12-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-3.21 $-3.21 $-3.21 $-3.21 $-2.97
Taux de croissance 3
Données annuelles Taux de croissance pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +176.3% 114.5% -14.0% 34.2% 29.8% 41.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +0.7% 35.3% 14.4% 35.0% · · · · · · · · ·
Revenue CAGR 5Y 35.4% · · · · · · · · · · ·
Valorisation (TTM) 13
Données annuelles Valorisation (TTM) pour PTCT
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Net Income TTM 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
Market Cap 11-point trend, +263.4% $6.19B $3.51B $2.09B · $2.82B $4.25B $2.97B $1.74B $694M $373M $1.10B $1.70B
Enterprise Value 10-point trend, +430.1% $4.53B $2.65B $1.49B · $2.48B $3.46B $2.60B $1.66B $648M $239M $855M ·
P/E 12-point trend, +156.0% 9.8 -9.5 -3.3 -4.9 -5.4 -9.2 -11.2 -10.7 -5.2 -3.4 -10.1 -17.4
P/S 11-point trend, -94.7% 3.6 4.3 2.2 · 5.2 11.2 9.7 6.6 3.6 4.5 29.9 67.5
P/B 11-point trend, -628.2% -30.1 -3.2 -2.5 · 1961.8 8.8 5.0 5.0 4.4 3.1 4.9 5.7
P / Cash Flow 11-point trend, +129.3% 8.7 -32.6 -13.2 · -11.2 -21.9 -30.2 -62.8 -69.0 -3.6 -8.8 -29.7
P / FCF 11-point trend, +132.0% 8.8 -30.7 -11.2 · -10.1 -20.1 -26.5 -50.0 -52.7 -3.5 -8.6 -27.5
EV / EBITDA 10-point trend, +197.8% 5.0 -11.7 -7.4 · -8.0 -8.9 -12.5 -18.6 -13.9 -1.8 -5.1 ·
EV / FCF 10-point trend, +195.9% 6.5 -23.2 -8.0 · -8.9 -16.3 -23.2 -47.9 -49.2 -2.3 -6.7 ·
EV / Revenue 10-point trend, -88.7% 2.6 3.3 1.6 · 4.6 9.1 8.5 6.3 3.3 2.9 23.2 ·
Earnings Yield 12-point trend, +278.4% 10.2% -10.5% -30.4% -20.4% -18.6% -10.9% -8.9% -9.3% -19.2% -29.4% -9.9% -5.7%

États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années

Compte de résultat
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenu $1.73B$807M$938M$699M$539M
Marge d'exploitation % 50.1%-37.5%-46.9%-69.5%
Résultat net $683M$-363M$-627M$-559M$-524M
BPA dilué $7.78$-4.73$-8.37$-7.79$-7.43
Bilan
2025-12-312024-12-312023-12-312022-12-312021-12-31
Dette / Capitaux propres -1.4-0.3-0.3300.0
Ratio de liquidité 2.32.42.01.9
Ratio de liquidité réduite 2.22.21.71.7
Flux de trésorerie
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flux de trésorerie libre $702M$-114M$-187M$-280M

Signaux de trading Signaux d'achat/vente récents avec prix d'entrée et ratio risque/récompense

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Détenteurs institutionnels (13F) 403 déclarants · $5.4B total · Au 30 juin 2026

Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.

Activité institutionnelle — Q2 2026 vs trimestre précédent
Nouvelles positions Positions clôturées Augmenté Diminué Variation nette des actions
83 (+22 vs T. préc.) 43 (-9 vs T. préc.) 133 (-4 vs T. préc.) 109 (+6 vs T. préc.) +2.1M

Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.

Institution Valeur Actions % de 13F suivies Type
RTW INVESTMENTS, LP $631 875 072 7 746 415 11,70% Actions
JANUS HENDERSON GROUP PLC $479 178 655 7 034 622 8,87% Actions
VANGUARD PORTFOLIO MANAGEMENT LLC $401 986 014 4 928 111 7,45% Actions
STATE STREET CORP $375 136 515 4 598 952 6,95% Actions
VANGUARD CAPITAL MANAGEMENT LLC $305 000 589 3 739 127 5,65% Actions
WELLINGTON MANAGEMENT GROUP LLP $292 435 873 3 585 091 5,42% Actions
WESTFIELD CAPITAL MANAGEMENT CO LP $159 563 645 1 956 156 2,96% Actions
GEODE CAPITAL MANAGEMENT, LLC $155 132 041 1 901 417 2,87% Actions
Hood River Capital Management LLC $141 818 662 1 738 613 2,63% Actions
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $140 519 660 1 722 688 2,60% Actions
TANG CAPITAL MANAGEMENT LLC $122 355 000 1 500 000 2,27% Actions
Driehaus Capital Management LLC $117 469 528 1 440 107 2,18% Actions
Jefferies Financial Group Inc. $110 693 916 1 357 042 2,05% Actions
FULLER & THALER ASSET MANAGEMENT, INC. $94 361 749 1 156 819 1,75% Actions
Pictet Asset Management Holding SA $93 629 635 1 147 844 1,73% Actions
ARMISTICE CAPITAL, LLC $87 393 690 1 071 395 1,62% Actions
Blue Sparrow, LLC /DE $85 705 599 1 050 700 1,59% Actions
D. E. Shaw & Co., Inc. $77 478 857 949 845 1,44% Actions
Palo Alto Investors LP $74 950 268 918 846 1,39% Actions
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $64 449 436 790 112 1,19% Actions
RENAISSANCE TECHNOLOGIES LLC $59 015 895 723 500 1,09% Actions
Boston Partners $57 080 953 699 871 1,06% Actions
FMR LLC $56 956 987 698 259 1,05% Actions
BANK OF AMERICA CORP /DE/ $56 350 840 690 828 1,04% Actions
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $53 377 940 654 382 0,99% Actions
DIMENSIONAL FUND ADVISORS LP $51 486 821 631 199 0,95% Actions
VANGUARD FIDUCIARY TRUST CO $47 953 943 587 887 0,89% Actions
Ensign Peak Advisors, Inc $41 442 128 508 056 0,77% Actions
AMERICAN CENTURY COMPANIES INC $40 866 277 500 995 0,76% Actions
MANUFACTURERS LIFE INSURANCE COMPANY, THE $36 050 432 441 957 0,67% Actions
Parkman Healthcare Partners LLC $35 539 315 435 691 0,66% Actions
LOOMIS SAYLES & CO L P $35 387 921 433 835 0,66% Actions
Defilade Capital Management, L.P. $35 376 827 433 699 0,66% Actions
GOLDMAN SACHS GROUP INC $34 153 522 418 702 0,63% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $32 274 149 395 662 0,60% Actions
BNP PARIBAS FINANCIAL MARKETS $30 892 190 378 720 0,57% Actions
Qube Research & Technologies Ltd $25 398 777 311 374 0,47% Actions
ARMISTICE CAPITAL, LLC $24 471 000 300 000 0,45% Option d'achat
Public Sector Pension Investment Board $23 249 326 285 023 0,43% Actions
SEGALL BRYANT & HAMILL, LLC $22 165 424 271 735 0,41% Actions
CITADEL ADVISORS LLC $20 338 011 249 332 0,38% Actions
MORGAN STANLEY $18 990 210 232 808 0,35% Actions
Boxer Capital Management, LLC $16 314 000 200 000 0,30% Actions
RHUMBLINE ADVISERS $15 718 994 192 706 0,29% Actions
AMERIPRISE FINANCIAL INC $13 904 178 170 457 0,26% Actions
PRUDENTIAL FINANCIAL INC $13 746 176 168 520 0,25% Actions
BlackRock, Inc. $13 589 562 166 600 0,25% Actions
Rock Springs Capital Management LP $13 238 648 162 298 0,25% Actions
Hudson Bay Capital Management LP $13 033 091 159 778 0,24% Actions
Russell Investments Group, Ltd. $12 687 724 155 544 0,23% Actions
Schonfeld Strategic Advisors LLC $12 025 457 147 425 0,22% Actions
MARSHALL WACE, LLP $11 724 301 143 733 0,22% Actions
Swiss National Bank $11 539 300 141 465 0,21% Actions
Universal- Beteiligungs- und Servicegesellschaft mbH $11 063 583 135 633 0,20% Actions
Legal & General Group Plc $10 362 979 127 044 0,19% Actions
CITIGROUP INC $9 272 143 113 671 0,17% Actions
FIRST TRUST ADVISORS LP $9 246 285 113 354 0,17% Actions
Longaeva Partners L.P. $9 119 771 111 803 0,17% Actions
JUPITER ASSET MANAGEMENT LTD $8 927 184 109 442 0,17% Actions
SCHRODER INVESTMENT MANAGEMENT GROUP $8 215 404 100 716 0,15% Actions
SECTOR GAMMA AS $8 157 000 100 000 0,15% Actions
WCM INVESTMENT MANAGEMENT, LLC $7 651 184 93 799 0,14% Actions
PANAGORA ASSET MANAGEMENT INC $7 256 141 88 956 0,13% Actions
VOYA INVESTMENT MANAGEMENT LLC $7 239 501 88 752 0,13% Actions
ALLIANCEBERNSTEIN L.P. $7 217 488 105 937 0,13% Actions
Aquatic Capital Management LLC $6 808 648 83 470 0,13% Actions
XTX Topco Ltd $6 682 459 81 923 0,12% Actions
MOORE CAPITAL MANAGEMENT, LP $6 165 713 75 588 0,11% Actions
PINNACLE ASSOCIATES LTD $5 745 383 70 435 0,11% Actions
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $5 744 722 84 320 0,11% Actions
VANGUARD ASSET MANAGEMENT, Ltd $5 614 300 68 828 0,10% Actions
Capricorn Fund Managers Ltd $5 212 323 63 900 0,10% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5 000 241 61 300 0,09% Option d'achat
INTECH INVESTMENT MANAGEMENT LLC $4 696 882 57 581 0,09% Actions
ExodusPoint Capital Management, LP $4 672 166 57 278 0,09% Actions
LOS ANGELES CAPITAL MANAGEMENT LLC $4 561 884 55 926 0,08% Actions
BARCLAYS PLC $4 169 858 51 120 0,08% Actions
ORBIMED ADVISORS LLC $4 005 087 49 100 0,07% Actions
MetLife Investment Management, LLC $3 932 653 48 212 0,07% Actions
Point72 Europe (London) LLP $3 829 919 62 407 0,07% Actions
MILLENNIUM MANAGEMENT LLC $3 792 516 46 494 0,07% Actions
Phocas Financial Corp. $3 766 087 46 170 0,07% Actions
MARTINGALE ASSET MANAGEMENT L P $3 627 826 44 475 0,07% Actions
Quadrature Capital Ltd $3 589 488 44 005 0,07% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3 531 981 43 300 0,07% Option de vente
STATE OF WISCONSIN INVESTMENT BOARD $3 436 299 42 127 0,06% Actions
CREDIT AGRICOLE S A $3 344 370 41 000 0,06% Actions
Fisher Asset Management, LLC $3 322 345 40 730 0,06% Actions
HSBC HOLDINGS PLC $3 200 425 38 732 0,06% Actions
NEW YORK STATE COMMON RETIREMENT FUND $3 134 490 38 427 0,06% Actions
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $3 114 179 38 178 0,06% Actions
CenterBook Partners LP $3 082 938 37 795 0,06% Actions
Rafferty Asset Management, LLC $3 069 805 37 634 0,06% Actions
FIFTH THIRD BANCORP $3 044 843 37 328 0,06% Actions
BURNEY CO/ $3 044 192 37 320 0,06% Actions
Vanguard Global Advisers, LLC $3 033 180 37 185 0,06% Actions
Arrowpoint Investment Partners (Singapore) Pte. Ltd. $3 007 731 36 873 0,06% Actions
Louisiana State Employees Retirement System $2 969 148 36 400 0,05% Actions
JANE STREET GROUP, LLC $2 854 950 35 000 0,05% Option de vente
CASTLEARK MANAGEMENT LLC $2 765 223 33 900 0,05% Actions

Initiés de la société 33 initiés · 13 dirigeants · 14 administrateurs

Dirigeant Rôle Dernière activité Actions détenues Achats 12m Ventes 12m Net 12m
Stuart Walter Peltz Chief Executive Officer 1 février 2022 S 38 728 0 0 $0
Pierre Gravier CHIEF FINANCIAL OFFICER 14 juillet 2026 S 83 986 0 1 $-280 743
Emily Luisa Hill Chief Financial Officer 1 février 2022 S 37 169 0 0 $0
Shane William Charles Kovacs Chief Financial Officer 9 mai 2017 M 37 850 0 0 $0
Claudia De Oliveira Ribeiro Hirawat President 15 janvier 2015 M 39 247 0 0 $0
Marcio Souza Chief Operating Officer 10 février 2020 M 6 744 0 0 $0
Neil Gregory Almstead CHIEF TECHNICAL OPS OFFICER 9 juillet 2026 M 60 299 0 20 $-9 184 852
Mark Elliott Boulding EXEC. VP AND CLO 6 juillet 2026 M 105 272 0 12 $-1 254 986
Christine Marie Utter SVP, CHIEF ACCOUNTING OFFICER 17 juin 2026 M 70 199 0 1 $-1 487 474
Eric Pauwels CHIEF BUSINESS OFFICER 10 juin 2026 S 73 411 0 28 $-7 477 160
Mark Rothera Chief Commercial Officer 24 mai 2017 M 33 739 0 0 $0
Tuyen Ong Chief Medical Officer 3 janvier 2017 A 6 000 0 0 $0
Robert J. Spiegel Chief Medical Officer 4 janvier 2016 A 3 239 0 0 $0
Hege Elisabeth Sollie-Zetlmayer Administrateur 28 juillet 2026 A 52 526 0 0 $0
Mary L. Smith Administrateur 9 juillet 2026 M 21 813 0 2 $-1 425 060
Stephanie Okey Administrateur 7 janvier 2022 A 4 163 0 0 $0
Emma Reeve Administrateur 7 janvier 2022 A 7 528 0 0 $0
Allan Steven Jacobson Administrateur 7 janvier 2022 A 8 348 0 0 $0
Dawn Svoronos Administrateur 7 janvier 2022 A 29 755 0 0 $0
Jerome B Zeldis Administrateur 7 janvier 2022 A 6 500 0 0 $0
Cameron Geoffrey Mcdonough Administrateur 3 janvier 2017 A 0 0 $0
Adam Koppel Administrateur 3 janvier 2017 A 2 333 333 0 0 $0
Ronald C Renaud JR Administrateur 3 janvier 2017 A 0 0 $0
Richard Aldrich Administrateur 8 juin 2015 M 0 0 0 $0
Michael L Kranda Administrateur 16 mars 2015 S 2 242 0 0 $0
Axel Bolte Administrateur 25 juin 2013 P 20 000 0 0 $0
HBM Healthcare Investments (Cayman) Ltd. Détenteur de 10% 17 décembre 2013 S 2 441 504 0 0 $0
Matthew B. Klein 4 août 2026 S 383 868 0 1 $-705 722
Michael Schmertzler 2 janvier 2026 A 163 266 0 0 $0
Glenn Steele JR MD PHD 2 janvier 2026 A 22 500 0 1 $-916 200
David P Southwell 2 janvier 2026 A 20 850 0 0 $0
Complete Pharma Holdings II, LLC 28 avril 2017 J 0 0 0 $0
CREDIT SUISSE/ 25 juin 2013 C 2 256 882 0 0 $0

Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché

Activistes et détenteurs de 5%+ 3 participations

Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.

Déclarant Déposé Participation Statut Objectif Dépôt
Brookside Capital Partners Fund, L.P., Brookside Capital Trading Fund, L.P. ×5 dépôts 30 janvier 2015 Dépôt initial SEC
HBM Healthcare Investments (Cayman) Ltd. (“HBM”) ×2 dépôts 12 novembre 2014 Dépôt initial SEC
HBM Healthcare Investments (Cayman) Ltd. 5 juillet 2013 Dépôt initial SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Détention d'ETF Détenu par 87 ETFs

Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.

Fonds Poids Unités Au Source
IBRN · iShares Trust 3,81% 4 145 SH 8 août 2026 Quotidien
PSCH · Invesco Exchange-Traded Fund Trust … 3,08% 71 992 SH 8 août 2026 Quotidien
PBE · Invesco Exchange-Traded Fund Trust 2,59% 128 216 SH 8 août 2026 Quotidien
XSMO · Invesco Exchange-Traded Fund Trust 1,52% 642 023 SH 8 août 2026 Quotidien
BBP · ETFis Series Trust I 1,37% 12 510 NS 30 avril 2026 N-PORT
SIXS · EXCHANGE TRADED CONCEPTS TRUST 1,30% 22 380 NS 31 mai 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 1,25% 23 662 SH 8 août 2026 Quotidien
GURU · Global X Funds 1,03% 9 268 NS 30 avril 2026 N-PORT
LABU · Direxion Shares ETF Trust 0,93% 73 928 NS 30 avril 2026 N-PORT
VAMO · Cambria ETF Trust 0,83% 10 625 NS 30 avril 2026 N-PORT
VIOG · VANGUARD ADMIRAL FUNDS 0,74% 98 733 SH 8 août 2026 Quotidien
VMAX · Lattice Strategies Trust 0,72% 5 120 NS 30 avril 2026 N-PORT
IJT · iShares Trust 0,66% 770 376 SH 8 août 2026 Quotidien
FNY · First Trust Exchange-Traded AlphaDE… 0,51% 40 257 NS 30 avril 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0,49% 3 490 NS 31 mai 2026 N-PORT
CLSE · Trust for Professional Managers 0,49% 40 488 NS 31 mai 2026 N-PORT
IBB · iShares Trust 0,44% 588 017 SH 8 août 2026 Quotidien
HQGO · Lattice Strategies Trust 0,43% 3 203 NS 30 avril 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0,41% 4 514 SH 8 août 2026 Quotidien
OASC · Unified Series Trust 0,40% 4 569 NS 31 mai 2026 N-PORT
BRNY · EA Series Trust 0,40% 34 057 NS 30 avril 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0,37% 290 018 SH 8 août 2026 Quotidien
XJR · iShares Trust 0,37% 9 802 SH 8 août 2026 Quotidien
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,34% 35 034 NS 31 mai 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0,34% 75 795 SH 8 août 2026 Quotidien
ESSC · Strategy Shares 0,34% 1 335 NS 30 avril 2026 N-PORT
IJR · iShares Trust 0,32% 5 058 562 SH 8 août 2026 Quotidien
IWO · iShares Trust 0,31% 641 280 SH 8 août 2026 Quotidien
BIB · ProShares Trust 0,31% 3 062 NS 31 mai 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0,31% 11 451 NS 31 mai 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,30% 39 411 NS 31 mai 2026 N-PORT
SAA · ProShares Trust 0,26% 961 NS 31 mai 2026 N-PORT
ROUS · Lattice Strategies Trust 0,25% 22 443 NS 30 avril 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,24% 27 276 NS 30 avril 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0,23% 2 877 NS 30 avril 2026 N-PORT
AFSM · First Trust Exchange-Traded Fund VI… 0,23% 3 003 NS 31 mai 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0,20% 477 030 SH 8 août 2026 Quotidien
FNX · First Trust Exchange-Traded AlphaDE… 0,20% 39 967 NS 30 avril 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0,19% 1 099 640 SH 8 août 2026 Quotidien
PRFZ · Invesco Exchange-Traded Fund Trust 0,18% 72 691 SH 8 août 2026 Quotidien
IWM · iShares Trust 0,18% 2 102 256 SH 8 août 2026 Quotidien
LRGF · iShares Trust 0,16% 84 151 SH 8 août 2026 Quotidien
ISCG · iShares Trust 0,16% 22 792 SH 8 août 2026 Quotidien
RSSL · Global X Funds 0,16% 34 125 NS 30 avril 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,15% 11 071 NS 30 avril 2026 N-PORT
ITWO · ProShares Trust 0,15% 3 710 NS 31 mai 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,14% 35 428 SH 8 août 2026 Quotidien
FSMD · FIDELITY COVINGTON TRUST 0,14% 49 932 NS 30 avril 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,14% 5 350 SH 8 août 2026 Quotidien
SMDX · Tidal Trust III 0,13% 2 579 NS 30 avril 2026 N-PORT