GYRE Gyre Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$6.80
Price · Aug 18, 2026
Fundamentals as of Aug 7, 2026

GYRE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$6.80
Market Cap
$621M
P/E (TTM)
340.0
EPS (TTM)
$0.02
Revenue (TTM)
$117M
Div Yield
ROE
11.7%
Debt/Equity
52W Range
$5 – $9

GYRE Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $117M
8-point trend, +11352.7%
2017-12-31 2025-12-31
EPS $0.02
5-point trend, +100.7%
2021-12-31 2025-12-31
Free Cash Flow $-180.0K
6-point trend, +99.0%
2016-12-31 2025-12-31
Margins 8.5%
2-point trend, +0.4%
2023-12-31 2024-12-31

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
GYRE
Peer Median
P/E (TTM)
5-point trend, +7522.0%
340.0
19.6
P/S (TTM)
5-point trend, -94.5%
5.3
6.4
P/B
5-point trend, -77.9%
5.9
2.6
Price / FCF
5-point trend, -5646.4%
-3449.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
GYRE
Peer Median
Operating Margin
4-point trend, +103.6%
9.8%
Net Profit Margin
4-point trend, +103.2%
8.5%
-104.2%
ROA
5-point trend, +111.7%
6.8%
-40.3%
ROE
5-point trend, +117.6%
11.7%
-42.4%
ROIC
4-point trend, -82.1%
7.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
GYRE
Peer Median
Current Ratio
5-point trend, +11.3%
5.6
5.4
Quick Ratio
5-point trend, -1.7%
4.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
GYRE
Peer Median
Revenue YoY
5-point trend, +1488.8%
10.2%
Revenue CAGR 3Y
5-point trend, +1488.8%
4.5%
Revenue CAGR 5Y
5-point trend, +1488.8%
41.0%
EPS YoY
5-point trend, +100.7%
-60.0%
Net Income YoY
5-point trend, +111.2%
-44.8%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
GYRE
Peer Median
EPS (Diluted)
5-point trend, +100.7%
$0.02

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
GYRE
Peer Median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

Dividend Yield
Payout Ratio
5Y Div CAGR
Ex-dateAmount
Jan. 13, 2023$3.6000
Sept. 21, 2022$21.4500
Aug. 20, 2015$896.1750

GYRE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 9 analysts
  • Strong Buy 3 33.3%
  • Buy 5 55.6%
  • Hold 1 11.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

3 analysts · 2026-08-14
Median target $18.00 +164.7%
Mean target $18.67 +174.5%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.01%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.12 $-0.09 -0.03%
March 31, 2026 $-0.04 $-0.07 0.03%
Dec. 31, 2025 $0.05 $0.06 -0.01%
Sept. 30, 2025 $0.08 $0.03 0.05%
June 30, 2025 $0.02 $0.03 -0.01%
March 31, 2025 $0.03 $0.03 -0.00%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
GYRE $645M 353.0 10.2% 8.5% 11.7%
STTK $231M -5.2 -82.5% -4880.9% -70.0%
RGNX $733M -3.8 104.5% -113.8% -122.5%
BBOT $1.00B -2.9 -146.2%
IRWD $550M 22.5 -15.7% 8.1% -8.5%
ALLO $314M -1.6 -76.8% -59.9%
SGMT -3.7 -42.3%
TECX $391M -5.2 -27.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 9-point trend, +42295.6% $117M $106M $113M $102M $7M $21M · $6.0K $1M · · $275.0K
Cost of Revenue 4-point trend, +13.0% $5M $4M $5M $5M · · · · · · · ·
Gross Profit 3-point trend, +4.5% · $102M $109M $97M · · · · · · · ·
R&D Expense 11-point trend, +160.1% $14M $12M $14M · $69M $53M $44M $21M $13M $12M $6M $5M
SG&A Expense 12-point trend, +413.0% $21M $16M $15M $17M $19M $16M $13M $12M $10M $9M $10M $4M
Operating Expenses 12-point trend, +1027.5% $105M $90M $176M $88M $95M $78M $57M $34M $23M $21M $16M $9M
Operating Income 12-point trend, +253.0% $11M $16M $-67M $9M $-88M $-57M $-57M $-34M $-22M $-20M $-14M $-8M
Interest Expense 2-point trend, +6326.1% · · · · · · · · · · $1M $23.0K
Other Non-op 11-point trend, -361.7% $-2M $-2M $-2M · $-78.0K $-91.0K $-39.0K $2M $-1.0K $86.0K $131.0K $575.0K
Pretax Income 6-point trend, +149.5% $14M $23M $-77M $9M $-88M · · · · · · $-29M
Income Tax 5-point trend, +30.8% $5M $5M $9M $5M · · · · · · · $3M
Net Income 12-point trend, +249.4% $10M $18M $-85M $4M $-88M $-56M $-55M $-30M $-22M $-17M $-15M $-7M
EPS (Basic) 5-point trend, +102.1% $0.06 $0.14 $-1.41 $0.04 $-2.87 · · · · · · ·
EPS (Diluted) 5-point trend, +100.7% $0.02 $0.05 $-1.41 $0.03 $-2.87 · · · · · · ·
Shares (Basic) 5-point trend, +191.6% 89,344,622 85,094,948 65,831,675 63,588,119 30,640,977 · · · · · · ·
Shares (Diluted) 5-point trend, +236.7% 103,180,037 102,293,526 65,831,675 75,686,406 30,640,977 · · · · · · ·
EBITDA 10-point trend, +147.6% $14M $18M $-66M $-8M · $-57M $-57M · $-22M $-20M $-13M $-29M
Balance Sheet 27
Annual Balance Sheet data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +3086.0% $49M $12M $34M $25M $44M $30M $15M $31M $14M $10M $29M $2M
Short-term Investments 10-point trend, -69.9% $15M $15M · · $3M $49M $61M $89M $18M $7M $3M $51M
Receivables 7-point trend, +21941.1% $31M $20M $15M · $2M $3M $15M · · · · $141.0K
Inventory 4-point trend, +66.1% $10M $6M $4M $6M · · · · · · · ·
Prepaid Expense 11-point trend, +9233.0% $10M $3M · $2M $3M $7M $4M $4M $1M $958.0K $2M $103.0K
Other Current Assets 4-point trend, +76.6% $1M $1M $1M $843.0K · · · · · · · ·
Current Assets 12-point trend, +7115.6% $149M $65M $57M $50M $51M $90M $96M $124M $39M $38M $69M $2M
PP&E (Net) 12-point trend, +2924.0% $28M $24M $23M $18M $970.0K $433.0K $304.0K $386.0K $276.0K $444.0K $698.0K $911.0K
PP&E (Gross) 9-point trend, +409.9% $39M $29M $28M $22M · · · $671.0K $2M $2M $6M $8M
Accum. Depreciation 10-point trend, +65.5% $11M $6M $4M $4M · · $400.0K $300.0K $2M $2M $6M $7M
Intangibles 4-point trend, +1491.6% $5M $273.0K $273.0K $297.0K · · · · · · · ·
Other Non-current Assets 10-point trend, +63433.3% $8M $3M $995.0K $3M $472.0K $528.0K $257.0K $543.0K $128.0K · · $12.0K
Total Assets 12-point trend, +7272.1% $220M $125M $117M $85M $56M $95M $99M $125M $40M $38M $70M $3M
Accounts Payable 12-point trend, +436.1% $1M $108.0K $355.0K $122.0K $6M $6M $4M $1M $747.0K $837.0K $939.0K $249.0K
Accrued Liabilities · · · · · · · · · · · $3M
Current Liabilities 12-point trend, +918.1% $24M $20M $20M $12M $14M $18M $29M $5M $9M $22M $38M $2M
Capital Leases 7-point trend, +74.6% $2M $885.0K $199.0K $121.0K $408.0K $981.0K $1M · · · · ·
Other Non-current Liabilities 4-point trend, +2638.2% $2M $7.0K $49.0K $55.0K · · · · · · · ·
Total Liabilities 12-point trend, +808.7% $31M $27M $38M $13M $15M $19M $30M $5M $9M $22M $38M $3M
Long-term Debt · · · · · · · · · · · $0
Common Stock 12-point trend, +167.6% $91.0K $86.0K $77.0K $64.0K $31.0K $22.0K $12.0K $12.0K $6.0K $1.0K $1.0K $34.0K
Paid-in Capital 12-point trend, +2396.3% $173M $136M $68M $33M $444M $391M $327M $323M $204M $164M $162M $7M
Retained Earnings 12-point trend, +3.2% $-113M $-73M $-86M $7M $-403M $-315M $-259M $-203M $-173M $-148M $-131M $-116M
AOCI 10-point trend, -22800.0% $-908.0K $-3M $-2M $-392.0K · $5.0K $34.0K $-4.0K · $-1.0K $1.0K $4.0K
Stockholders' Equity 12-point trend, +157.2% $62M $63M $-16M $43M $41M $76M $68M $120M $31M $16M $31M $-109M
Liabilities + Equity 12-point trend, +7272.1% $220M $125M $117M $85M $56M $95M $99M $125M $40M $38M $70M $3M
Shares Outstanding 12-point trend, +24516.7% 91,314,007 86,307,544 76,595,616 63,588,119 31,409,707 22,097,820 12,040,835 11,954,528 6,081,230 801,756 762,005 370,944
Cash Flow 19
Annual Cash Flow data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +264.9% $2M $2M $1M $1M $290.0K $138.0K $146.0K $149.0K $173.0K $389.0K $470.0K $680.0K
Stock-based Comp 12-point trend, +2833.2% $7M $831.0K $7M $13M $3M $4M $3M $3M $863.0K $635.0K $326.0K $244.0K
Deferred Tax 5-point trend, -1638.9% $-1M $-1M $-834.0K $-890.0K · · · · · · · $72.0K
Amort. of Intangibles 4-point trend, +188.0% $576.0K $38.0K $100.0K $200.0K · · · · · · · ·
Restructuring 3-point trend, +1011000.00 · · · $1M $4M · · · $0 · · ·
Other Non-cash 10-point trend, -202.3% $-17M $-23M $104M $-26M · $-3M $8M · $585.0K $-3M $-5M $-6M
Operating Cash Flow 12-point trend, +115.8% $1M $-4M $26M $11M $-84M $-55M $-44M $-29M $-20M $-18M $-19M $-6M
CapEx 11-point trend, +29650.0% $1M $2M $9M $5M $839.0K · $64.0K $376.0K $23.0K $468.0K $272.0K $4.0K
Investing Cash Flow 9-point trend, +95.8% $-474.0K $-20M $-20M $-14M $48M $10M $27M $-71M $-11M · · ·
Net Debt Issued · · · · · · · · · · · $-1M
Stock Issued 4-point trend, +161.1% · $773.0K · · · · · · $5M $958.0K · $296.0K
Stock Repurchased · · · · · · · · · · $82.0K ·
Net Stock Activity 5-point trend, +161.1% · $773.0K · · · · · · $5M $958.0K $-82.0K $296.0K
Dividends Paid · · · $45M · · · · · · · ·
Financing Cash Flow 9-point trend, +15.6% $24M $2M $2M $-45M $50M $60M $327.0K $111M $21M · · ·
Net Change in Cash 12-point trend, +2067.1% $25M $-22M $8M $-5M $14M $15M $-16M $11M $-10M $-19M $28M $-1M
Taxes Paid 4-point trend, -10.9% $6M $9M $6M $6M · · · · · · · ·
Free Cash Flow 8-point trend, +99.5% $-180.0K $-6M $17M · · · $-44M · $-20M $-19M $-19M $-34M
Levered FCF · · · · · · · · · · · $-35M
Profitability 8
Annual Profitability data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Gross Margin 2-point trend, +0.4% · 96.3% 95.9% · · · · · · · · ·
Operating Margin 5-point trend, +100.1% 9.8% 15.3% -59.3% · · -273.9% · · · · · -10805.1%
Net Margin 5-point trend, +100.1% 8.5% 16.9% -75.3% · · -268.5% · · · · · -11862.9%
Pretax Margin 4-point trend, +100.1% 12.4% 21.9% -67.8% · · · · · · · · -10596.0%
EBITDA Margin 5-point trend, +100.1% 12.0% 16.8% -58.3% · · -273.2% · · · · · -10677.5%
ROA 10-point trend, +126.8% 6.8% 14.8% -84.9% -19.6% · -58.2% -49.4% · -55.6% -31.5% -40.7% -25.3%
ROE 10-point trend, +101.1% 11.7% 75.4% 387.3% -214.5% · -66.1% -73.8% · -92.0% -71.4% 37.9% -1073.6%
ROIC 5-point trend, +124.3% 7.4% 19.7% 471.8% 41.4% · · · · · · · -30.5%
Liquidity & Solvency 3
Annual Liquidity & Solvency data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 10-point trend, -84.9% 5.6 3.3 2.9 1.7 · 5.0 3.3 · 4.5 1.7 1.8 37.1
Quick Ratio 10-point trend, -87.6% 4.6 2.4 1.7 1.3 · 4.6 3.2 · 3.7 0.8 0.9 36.9
Interest Coverage 2-point trend, +99.3% · · · · · · · · · · -9.3 -1291.9
Efficiency 3
Annual Efficiency data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 5-point trend, +37985.7% 0.8 0.9 1.1 · · 0.2 · · · · · 0.0
Inventory Turnover 2-point trend, -17.9% · 0.7 0.9 · · · · · · · · ·
Receivables Turnover 4-point trend, +250.6% 4.6 6.1 · · · 2.3 · · · · · 1.3
Per Share 7
Annual Per Share data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 10-point trend, -64.0% $1.16 $0.73 $-0.21 $-0.57 · $3.44 $5.68 · $5.06 $20.04 $2.75 $3.23
Revenue / Share 3-point trend, -34.4% $1.13 $1.03 $1.72 · · · · · · · · ·
Cash Flow / Share 4-point trend, +100.9% $0.01 $-0.04 $0.39 $-1.05 · · · · · · · ·
Cash / Share 10-point trend, -75.7% $0.41 $0.14 $0.44 $0.57 · $1.37 $1.28 · $2.38 $12.80 $2.55 $1.67
Dividend / Share · · · $0 · · · · · · · ·
Dividend Paid / Share · · · $1 · · · · · · · ·
EPS (TTM) 12-point trend, +101.4% $0.02 $0.05 $-1.41 $0.03 $-2.87 $-1.46 $-1.46 $-1.46 $-1.46 $-1.46 $-1.46 $-1.46
Growth Rates 7
Annual Growth Rates data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +115.8% 10.2% -6.8% 10.9% 1294.0% -65.0% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -94.1% 4.5% 143.4% 75.6% · · · · · · · · ·
Revenue CAGR 5Y 41.0% · · · · · · · · · · ·
EPS YoY -60.0% · · · · · · · · · · ·
EPS CAGR 3Y -12.6% · · · · · · · · · · ·
Net Income YoY -44.8% · · · · · · · · · · ·
Net Income CAGR 3Y 31.8% · · · · · · · · · · ·
Valuation (TTM) 13
Annual Valuation (TTM) data for GYRE
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 11-point trend, +42295.6% $117M $106M $113M $102M $7M $21M · $6.0K $1M $248.0K $248.0K $275.0K
Net Income TTM 12-point trend, +249.4% $10M $18M $-85M $4M $-88M $-56M $-55M $-30M $-22M $-17M $-15M $-7M
Market Cap 10-point trend, -99.5% $645M $1.04B $1.97B $300M · $2.09B $1.23B · $1.24B $117M $8.05B $139.98B
P/E 12-point trend, +112.4% 353.0 242.0 -18.2 265.0 -4.8 -64.8 -70.0 -81.1 -140.1 -100.2 -482.4 -2837.2
P/S 9-point trend, -100.0% 5.5 9.9 17.3 2.9 · 99.8 · · 1222.2 472.8 32458.2 509025.8
P/B 10-point trend, -99.5% 6.1 16.5 -124.3 -13.8 · 27.5 18.0 · 40.4 7.3 256.2 1283.2
P / Tangible Book 5-point trend, -76.9% 6.4 16.6 · 7.1 10.4 27.5 · · · · · ·
P / Cash Flow 10-point trend, +115.7% 638.3 -286.8 76.0 -9.1 · -38.0 -28.2 · -62.4 -6.3 -421.1 -4059.5
P / FCF 8-point trend, +11.8% -3581.5 -175.3 113.3 · · · -28.2 · -62.3 -6.2 -415.1 -4059.0
Dividend Yield · · · 15.0% · · · · · · · ·
Earnings Yield 12-point trend, +800.0% 0.28% 0.41% -5.5% 0.38% -21.0% -1.5% -1.4% -1.2% -0.71% -1.0% -0.21% -0.04%
Payout Ratio · · · -546.4% · · · · · · · ·
Annual Payout · · · $45M · · · · · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $117M$106M$113M$102M$7M
Gross Margin % 96.3%95.9%
Operating Margin % 9.8%15.3%-59.3%
Net Income $10M$18M$-85M$4M$-88M
Diluted EPS $0.02$0.05$-1.41$0.03$-2.87
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 5.63.32.91.7
Quick Ratio 4.62.41.71.3
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-180.0K$-6M$17M

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Institutional owners (13F) 63 filers · $55.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
17 (+6 vs prior Q) 7 (+4 vs prior Q) 26 (+8 vs prior Q) 8 (0 vs prior Q) +6.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
HSG Holding Ltd $24,714,470 3,750,299 44.65% Shares
VANGUARD GROUP INC $7,437,901 1,053,527 13.44% Shares
Octagon Capital Advisors LP $6,289,601 954,416 11.36% Shares
VANGUARD CAPITAL MANAGEMENT LLC $5,778,949 876,927 10.44% Shares
GEODE CAPITAL MANAGEMENT, LLC $3,006,906 456,126 5.43% Shares
STATE STREET CORP $1,617,199 245,402 2.92% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,214,445 184,286 2.19% Shares
SBI Securities Co., Ltd. $1,098,883 166,750 1.99% Shares
VANGUARD FIDUCIARY TRUST CO $995,571 151,073 1.80% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $816,850 123,953 1.48% Shares
GOLDMAN SACHS GROUP INC $568,289 86,235 1.03% Shares
Bank of New York Mellon Corp $227,935 34,588 0.41% Shares
ALLIANCEBERNSTEIN L.P. $171,392 24,590 0.31% Shares
STRS OHIO $170,022 25,800 0.31% Shares
DIMENSIONAL FUND ADVISORS LP $161,521 24,510 0.29% Shares
Nuveen, LLC $161,488 24,505 0.29% Shares
MILLENNIUM MANAGEMENT LLC $121,836 18,488 0.22% Shares
RHUMBLINE ADVISERS $111,131 16,865 0.20% Shares
FMR LLC $98,679 14,974 0.18% Shares
BANK OF AMERICA CORP /DE/ $82,539 12,525 0.15% Shares
Polymer Capital Management (US) LLC $77,630 11,780 0.14% Shares
Vanguard Global Advisers, LLC $65,788 9,983 0.12% Shares
Police & Firemen's Retirement System of New Jersey $59,382 9,011 0.11% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $55,659 8,446 0.10% Shares
CITIGROUP INC $49,603 7,527 0.09% Shares
BlackRock, Inc. $28,752 4,363 0.05% Shares
Russell Investments Group, Ltd. $23,803 3,612 0.04% Shares
BNP PARIBAS FINANCIAL MARKETS $22,973 3,486 0.04% Shares
NORTHERN TRUST CORP $18,887 2,866 0.03% Shares
BARCLAYS PLC $18,558 2,816 0.03% Shares
NEW YORK STATE COMMON RETIREMENT FUND $17,793 2,700 0.03% Shares
Tower Research Capital LLC (TRC) $16,271 2,469 0.03% Shares
MORGAN STANLEY $16,106 2,444 0.03% Shares
Legal & General Group Plc $13,536 2,054 0.02% Shares
Ameritas Investment Partners, Inc. $4,501 683 0.01% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $4,454 639 0.01% Shares
ROYAL BANK OF CANADA $4,000 537 0.01% Shares
Activest Wealth Management $3,512 533 0.01% Shares
Arax Advisory Partners $1,621 246 0.00% Shares
MERCER GLOBAL ADVISORS INC /ADV $1,285 195 0.00% Shares
Sterling Capital Management LLC $1,061 161 0.00% Shares
GAMMA Investing LLC $962 146 0.00% Shares
CWM, LLC $725 104 0.00% Shares
Physician Wealth Advisors, Inc. $541 82 0.00% Shares
Bare Financial Services, Inc $521 79 0.00% Shares
WELLS FARGO & COMPANY/MN $435 66 0.00% Shares
JPMORGAN CHASE & CO $361 56 0.00% Shares
GoalVest Advisory LLC $330 50 0.00% Shares
Allworth Financial LP $251 38 0.00% Shares
DEUTSCHE BANK AG\ $244 37 0.00% Shares
OSAIC HOLDINGS, INC. $216 33 0.00% Shares
UBS Group AG $165 25 0.00% Shares
PRICE T ROWE ASSOCIATES INC /MD/ $100 15,031 0.00% Shares
Caitong International Asset Management Co., Ltd $99 15 0.00% Shares
Integrated Wealth Concepts LLC $94 14 0.00% Shares
EverSource Wealth Advisors, LLC $53 8 0.00% Shares
Farther Finance Advisors, LLC $53 8 0.00% Shares
Optiver Holding B.V. $40 6 0.00% Shares
Smartleaf Asset Management LLC $39 6 0.00% Shares
State of Alaska, Department of Revenue $34 5,219 0.00% Shares
ROTHSCHILD INVESTMENT LLC $7 1 0.00% Shares
Essential Partners LLC $7 1 0.00% Shares
Covestor Ltd $0 48 0.00% Shares

Company insiders 66 insiders · 26 officers · 32 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Ying Luo Chief Executive Officer June 8, 2026 A 2,565,226 0 2 $-82,927
Han Ying Chief Executive Officer Aug. 14, 2024 A 0 0 $0
Charles C Wu Chief Executive Officer Nov. 20, 2023 A 0 0 $0
Donald J Debethizy President and CEO May 4, 2012 A 798 0 0 $0
Thomas Wilson Eastling Chief Financial Officer May 4, 2026 A 15,000 0 0 $0
Ruoyu Chen Chief Financial Officer Jan. 7, 2026 A 0 0 $0
Seline E. Miller SVP Finance; Interim CFO & PAO Aug. 31, 2023 D 0 0 0 $0
Clinton Musil Chief Financial Officer Feb. 8, 2021 A 0 0 $0
Fletcher Payne Chief Financial Officer Aug. 12, 2019 A 3,744 0 0 $0
Mauri K Hodges Treasurer, CFO Aug. 14, 2015 A 1,159 0 0 $0
Alan A Musso SVP, Fin+Admin, CFO & Treas Oct. 17, 2014 A 57,799 0 0 $0
Songjiang Ma President May 28, 2025 S 2,806,084 0 0 $0
Weiguo Ye Chief Operating Officer June 18, 2026 M 700,000 0 16 $-869,947
Joshua Benjamin Bergmann GC and Corporate Secretary June 8, 2026 A 0 0 $0
Grant E. Blouse Chief Scientific Officer Aug. 9, 2022 P 9,417 0 0 $0
Howard Levy Chief Medical Officer Aug. 9, 2021 P 639 0 0 $0
Veronica Cai Controller March 13, 2020 P 7,353 0 0 $0
Edwin Madison Chief Scientific Officer Oct. 22, 2015 A 31,008 0 0 $0
Patrick C. Rock Secretary, GC Aug. 14, 2015 A 45,000 0 0 $0
Steven M. Toler VP, Clin Pharm Sciences Oct. 17, 2014 A 46,000 0 0 $0
David A. Hosford VP, Clin Dev & Reg Affairs Jan. 23, 2014 A 0 0 $0
Karen A Hicks VP, Human Resources Jan. 17, 2013 A 0 0 0 $0
Peter A Zorn SVP, Lgl Affrs, GC & Secretary Jan. 17, 2013 A 0 0 0 $0
Merouane Bencherif SVP and Senior Scien Fellow Jan. 17, 2013 A 15,938 0 0 $0
William S Caldwell SVP - Drug Discovery and Dev. Sept. 20, 2011 G 500 0 0 $0
Geoffrey C Dunbar SVP, Clin. Dev. & Reg. Affairs March 29, 2011 A 1,153 0 0 $0
Claire Weston Director Aug. 3, 2026 A 0 0 $0
Maxwell Kirkby Director Aug. 3, 2026 A 0 0 $0
Dan Weng Director June 10, 2026 A 0 0 $0
Ping Zhang Director June 10, 2026 A 0 0 $0
Rodney L Nussbaum Director June 10, 2026 A 0 0 $0
Renate Parry Director June 10, 2026 A 0 0 $0
Gordon Carmichael Director June 10, 2026 A 0 0 $0
David M. Epstein Director June 10, 2026 A 0 0 $0
Nassim Usman Director June 28, 2024 M 1,636 0 0 $0
Andrea Hunt Director Aug. 31, 2023 D 0 0 0 $0
Augustine Lawlor Director Aug. 31, 2023 D 0 0 0 $0
Geoffrey Ling M.D. Director Jan. 7, 2022 A 31,790 0 0 $0
Eddie Williams Director Jan. 7, 2022 A 34,804 0 0 $0
Errol B Desouza Director Oct. 1, 2021 A 29,801 0 0 $0
Jeanne Y Jew Director Sept. 9, 2021 A 0 0 $0
Sharon Tetlow Director June 9, 2021 A 3,635 0 0 $0
John P Richard Director March 13, 2020 P 3,716 0 0 $0
Stephen A Hill Director Sept. 6, 2018 D 1,190 0 0 $0
Harold E Selick Director Jan. 16, 2018 A 16,614 0 0 $0
Jeff Himawan Director Aug. 20, 2015 J 1,179,352 0 0 $0
Alan W Dunton Director Aug. 14, 2015 A 10,000 0 0 $0
Charles A Blixt Director Aug. 14, 2015 A 10,000 0 0 $0
Julia R Brown Director Aug. 14, 2015 A 10,000 0 0 $0
SKALETSKY MARK B Director June 7, 2013 A 11,332 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 21 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Songjiang Ma, Yueying Zhu May 7, 2026 6.33% Amendment M&A / sale SEC
Ying Luo, Ping Lan May 6, 2026 8.60% Amendment M&A / sale SEC
GNI USA, Inc., GNI Group Ltd. ×4 filings May 6, 2026 69.10% Amendment M&A / sale SEC
Ying Luo (“Mr. Luo”), Ping Lan Sept. 6, 2024 Initial filing Passive investment SEC
Songjiang Ma (“Mr. Ma”), Yueying Zhu Sept. 6, 2024 Initial filing Passive investment SEC
GNI Group Ltd., GNI Hong Kong Limited, GNI USA, Inc. ×2 filings Oct. 31, 2023 Initial filing SEC
JDS1, LLC, CCUR Holdings, Inc., CIDM II, LLC, Julian D. Singer, David S. Oros ×13 filings Oct. 7, 2022 Initial filing Passive investment SEC
JEC II Associates, LLC, The Heidi S. Shippell-Heiland 2008 Irrevocable Trust, Michael Torok ×4 filings Sept. 22, 2022 Initial filing SEC
Julian Singer, JDS1, LLC 2, CCUR Holdings, Inc., David S. Oros ×3 filings Jan. 27, 2022 Initial filing SEC
22NW Fund, LP, 22 NW, LP, 22NW Fund GP, LLC, 22NW GP, Inc., Aron R. English ×2 filings Aug. 5, 2020 Initial filing SEC
CCUR Holdings, Inc., Wayne Barr, Jr., JDS1, LLC, David S. Oros, Julian Singer ×3 filings Jan. 17, 2020 Initial filing SEC
Morgenthaler Management Partners VIII, LLC (“MMP VIII”), Morgenthaler Partners VIII, L.P. (“MP VIII”), Robert C. Bellas, Jr. (“Bellas”), Ralph E. Christoffersen (“Christoffersen”), John Lutsi (“Lutsi”), Gary J. Morgenthaler (“Morgenthaler”), Robert D. Pavey (“Pavey”), Gary R. Little (“Little”) Feb. 14, 2018 Initial filing SEC
HealthCare Ventures VIII, L.P., HealthCare Partners VIII, L.P., HealthCare Partners VIII, LLC, James H. Cavanaugh, Ph.D., Harold R. Werner, John W. Littlechild, Christopher Mirabelli, Ph.D., Augustine Lawlor ×2 filings Feb. 9, 2018 Initial filing SEC
May 23, 2017 Initial filing SEC
New Enterprise Associates 10, Limited Partnership, NEA Partners 10, Limited Partnership, Michael James Barrett, Peter J. Barris, Scott D. Sandell ×4 filings March 29, 2017 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 18 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWO · iShares Trust 0.01% 117,803 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.00% 386,378 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.00% 5,185 NS April 30, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.00% 99,892 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.00% 41,237 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.00% 555 NS May 31, 2026 N-PORT
UWM · ProShares Trust 0.00% 435 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 441 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 1,907 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 11 NS May 31, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 18,000 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 238,693 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 614,654 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.00% 104,607 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 5,047 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 13,494 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 805 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 320 NS April 30, 2026 N-PORT