GYRE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $7.11
Market Cap (MRQ) $754M
P/E (TTM) -35.5
EPS (TTM) $-0.20
Revenue (TTM) $119M
ROE (TTM) -28.3%
52W Range $5–$9

GYRE Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 3
Ex-date Split Type
Oct. 31, 2023 1-for-15 Reverse
Feb. 13, 2017 1-for-15 Reverse
Aug. 21, 2015 1-for-7 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$117M
2017-12-31 → 2025-12-31
EPS$0.02
2021-12-31 → 2025-12-31
Free Cash Flow$-180.0K
2016-12-31 → 2025-12-31
Net margin-23.7%
2020-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend GYRE 5Y avg Peer Median Verdict
P/E (TTM) -35.55Y avg ≈167.4 ≈167.4 · ·
P/S (TTM) 6.35Y avg ≈8.9 ≈8.9 8.0 Undervalued
P/B (MRQ) 7.05Y avg ≈-28.9 ≈-28.9 3.2 Overvalued
Price / FCF (TTM) -47.95Y avg ≈-1214.5 ≈-1214.5 · ·
Price / Cash Flow (TTM) -52.05Y avg ≈104.6 ≈104.6 · ·
Price / Tangible Book (MRQ) 7.35Y avg ≈10.1 ≈10.1 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

13
Annualized Payout≈$3.60Paid annually
Ex-dateAmountCurrencyYield
Jan 13, 2023$3.60USD≈642.3%
Sep 21, 2022$21.45USD≈286.0%
Aug 20, 2015$896.18USD≈59.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 13.3%
Next Report Nov 05, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 18, 2026 $-0.12 $-0.09 -30.7%
March 31, 2026 May 8, 2026 $-0.10 $-0.07 -33.7%
Dec. 31, 2025 $0.05 $0.06 -13.5%
Sept. 30, 2025 $0.08 $0.03 194.1%
June 30, 2025 $0.02 $0.03 -34.6%
March 31, 2025 $0.03 $0.03 -2.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 17
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $117M$106M$113M$102M$7M$21M·$6.0K$1M··$275.0K
Cost of Revenue $5M$4M$5M$5M········
Gross Profit ·$102M$109M$97M········
R&D Expense $14M$12M$14M·$69M$53M$44M$21M$13M$12M$6M$5M
SG&A Expense $21M$16M$15M$17M$19M$16M$13M$12M$10M$9M$10M$4M
Operating Expenses $105M$90M$176M$88M$95M$78M$57M$34M$23M$21M$16M$9M
Operating Income $11M$16M$-67M$9M$-88M$-57M$-57M$-34M$-22M$-20M$-14M$-8M
Interest Expense ··········$1M$23.0K
Other Non-op $-2M$-2M$-2M·$-78.0K$-91.0K$-39.0K$2M$-1.0K$86.0K$131.0K$575.0K
Pretax Income $14M$23M$-77M$9M$-88M······$-29M
Income Tax $5M$5M$9M$5M·······$3M
Net Income $10M$18M$-85M$4M$-88M$-56M$-55M$-30M$-22M$-17M$-15M$-7M
EPS (Basic) $0.06$0.14$-1.41$0.04$-2.87·······
EPS (Diluted) $0.02$0.05$-1.41$0.03$-2.87·······
Shares (Basic) 89,344,62285,094,94865,831,67563,588,11930,640,977·······
Shares (Diluted) 103,180,037102,293,52665,831,67575,686,40630,640,977·······
EBITDA $14M$18M$-66M$-8M·$-57M$-57M·$-22M$-20M$-13M$-29M
Balance Sheet 27
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $49M$12M$34M$25M$44M$30M$15M$31M$14M$10M$29M$2M
Short-term Investments $15M$15M··$3M$49M$61M$89M$18M$7M$3M$51M
Receivables $31M$20M$15M·$2M$3M$15M····$141.0K
Inventory $10M$6M$4M$6M········
Prepaid Expense $10M$3M·$2M$3M$7M$4M$4M$1M$958.0K$2M$103.0K
Other Current Assets $1M$1M$1M$843.0K········
Current Assets $149M$65M$57M$50M$51M$90M$96M$124M$39M$38M$69M$2M
PP&E (Net) $28M$24M$23M$18M$970.0K$433.0K$304.0K$386.0K$276.0K$444.0K$698.0K$911.0K
PP&E (Gross) $39M$29M$28M$22M···$671.0K$2M$2M$6M$8M
Accum. Depreciation $11M$6M$4M$4M··$400.0K$300.0K$2M$2M$6M$7M
Intangibles $5M$273.0K$273.0K$297.0K········
Other Non-current Assets $8M$3M$995.0K$3M$472.0K$528.0K$257.0K$543.0K$128.0K··$12.0K
Total Assets $220M$125M$117M$85M$56M$95M$99M$125M$40M$38M$70M$3M
Accounts Payable $1M$108.0K$355.0K$122.0K$6M$6M$4M$1M$747.0K$837.0K$939.0K$249.0K
Accrued Liabilities ···········$3M
Current Liabilities $24M$20M$20M$12M$14M$18M$29M$5M$9M$22M$38M$2M
Capital Leases $2M$885.0K$199.0K$121.0K$408.0K$981.0K$1M·····
Other Non-current Liabilities $2M$7.0K$49.0K$55.0K········
Total Liabilities $31M$27M$38M$13M$15M$19M$30M$5M$9M$22M$38M$3M
Long-term Debt ···········$0
Common Stock $91.0K$86.0K$77.0K$64.0K$31.0K$22.0K$12.0K$12.0K$6.0K$1.0K$1.0K$34.0K
Paid-in Capital $173M$136M$68M$33M$444M$391M$327M$323M$204M$164M$162M$7M
Retained Earnings $-113M$-73M$-86M$7M$-403M$-315M$-259M$-203M$-173M$-148M$-131M$-116M
AOCI $-908.0K$-3M$-2M$-392.0K·$5.0K$34.0K$-4.0K·$-1.0K$1.0K$4.0K
Stockholders' Equity $62M$63M$-16M$43M$41M$76M$68M$120M$31M$16M$31M$-109M
Liabilities + Equity $220M$125M$117M$85M$56M$95M$99M$125M$40M$38M$70M$3M
Shares Outstanding 91,314,00786,307,54476,595,61663,588,11931,409,70722,097,82012,040,83511,954,5286,081,230801,756762,005370,944
Cash Flow 19
Metric Trend 202520242023202220212020201920182017201620152014
D&A $2M$2M$1M$1M$290.0K$138.0K$146.0K$149.0K$173.0K$389.0K$470.0K$680.0K
Stock-based Comp $7M$831.0K$7M$13M$3M$4M$3M$3M$863.0K$635.0K$326.0K$244.0K
Deferred Tax $-1M$-1M$-834.0K$-890.0K·······$72.0K
Amort. of Intangibles $576.0K$38.0K$100.0K$200.0K········
Restructuring ···$1M$4M···$0···
Other Non-cash $-17M$-23M$104M$-26M·$-3M$8M·$585.0K$-3M$-5M$-6M
Operating Cash Flow $1M$-4M$26M$11M$-84M$-55M$-44M$-29M$-20M$-18M$-19M$-6M
CapEx $1M$2M$9M$5M$839.0K·$64.0K$376.0K$23.0K$468.0K$272.0K$4.0K
Investing Cash Flow $-474.0K$-20M$-20M$-14M$48M$10M$27M$-71M$-11M···
Net Debt Issued ···········$-1M
Stock Issued ·$773.0K······$5M$958.0K·$296.0K
Stock Repurchased ··········$82.0K·
Net Stock Activity ·$773.0K······$5M$958.0K$-82.0K$296.0K
Dividends Paid ···$45M········
Financing Cash Flow $24M$2M$2M$-45M$50M$60M$327.0K$111M$21M···
Net Change in Cash $25M$-22M$8M$-5M$14M$15M$-16M$11M$-10M$-19M$28M$-1M
Taxes Paid $6M$9M$6M$6M········
Free Cash Flow $-180.0K$-6M$17M···$-44M·$-20M$-19M$-19M$-34M
Levered FCF ···········$-35M
Profitability 8
Metric Trend 202520242023202220212020201920182017201620152014
Gross Margin ·96.3%95.9%·········
Operating Margin 9.8%15.3%-59.3%··-273.9%·····-10805.1%
Net Margin 8.5%16.9%-75.3%··-268.5%·····-11862.9%
Pretax Margin 12.4%21.9%-67.8%········-10596.0%
EBITDA Margin 12.0%16.8%-58.3%··-273.2%·····-10677.5%
ROA 6.8%14.8%-84.9%-19.6%·-58.2%-49.4%·-55.6%-31.5%-40.7%-25.3%
ROE 11.7%75.4%387.3%-214.5%·-66.1%-73.8%·-92.0%-71.4%37.9%-1073.6%
ROIC 7.4%19.7%471.8%41.4%·······-30.5%
Liquidity & Solvency 3
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 5.63.32.91.7·5.03.3·4.51.71.837.1
Quick Ratio 4.62.41.71.3·4.63.2·3.70.80.936.9
Interest Coverage ··········-9.3-1291.9
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.80.91.1··0.2·····0.0
Inventory Turnover ·0.70.9·········
Receivables Turnover 4.66.1···2.3·····1.3
Per Share 7
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $1.16$0.73$-0.21$-0.57·$3.44$5.68·$5.06$20.04$2.75$3.23
Revenue / Share $1.13$1.03$1.72·········
Cash Flow / Share $0.01$-0.04$0.39$-1.05········
Cash / Share $0.41$0.14$0.44$0.57·$1.37$1.28·$2.38$12.80$2.55$1.67
Dividend / Share ···$0.24········
Dividend Paid / Share ···$1.43········
EPS (TTM) $0.02$0.05$-1.41$0.03$-2.87$-1.46$-1.46$-1.46$-1.46$-1.46$-1.46$-1.46
Growth Rates 7
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 10.2%-6.8%10.9%1294.0%-65.0%·······
Revenue CAGR 3Y 4.5%143.4%75.6%·········
Revenue CAGR 5Y 41.0%···········
EPS YoY -60.0%···········
EPS CAGR 3Y -12.6%···········
Net Income YoY -44.8%···········
Net Income CAGR 3Y 31.8%···········
Valuation (TTM) 13
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $117M$106M$113M$102M$7M$21M·$6.0K$1M$248.0K$248.0K$275.0K
Net Income TTM $10M$18M$-85M$4M$-88M$-56M$-55M$-30M$-22M$-17M$-15M$-7M
Market Cap $645M$1.04B$1.97B$300M·$2.09B$1.23B·$1.24B$117M$8.05B$139.98B
P/E 353.0242.0-18.2265.0-4.8-64.8-70.0-81.1-140.1-100.2-482.4-2837.2
P/S 5.59.917.32.9·99.8··1222.2472.832458.2509025.8
P/B 6.116.5-124.3-13.8·27.518.0·40.47.3256.21283.2
P / Tangible Book 6.416.6·7.110.427.5······
P / Cash Flow 638.3-286.876.0-9.1·-38.0-28.2·-62.4-6.3-421.1-4059.5
P / FCF -3581.5-175.3113.3···-28.2·-62.3-6.2-415.1-4059.0
Dividend Yield ···15.0%········
Earnings Yield 0.28%0.41%-5.5%0.38%-21.0%-1.5%-1.4%-1.2%-0.71%-1.0%-0.21%-0.04%
Payout Ratio ···-546.4%········
Annual Payout ···$45M········

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $117M $106M $113M $102M $7M
Gross Margin % · 96.3% 95.9% · ·
Operating Margin % 9.8% 15.3% -59.3% · ·
Net Income $10M $18M $-85M $4M $-88M
Diluted EPS $0.02 $0.05 $-1.41 $0.03 $-2.87

Institutional owners (13F) 62 filers · $65.5M total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 62
Value held $65.5M
New positions 11
Exited positions 7
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
11 (-4 vs prior Q) 7 (+4 vs prior Q) 31 (+13 vs prior Q) 9 (-2 vs prior Q) +5.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
HSG Holding Ltd $24,714,470 3,750,299 37.75% Shares
VANGUARD GROUP INC $8,483,219 1,201,589 12.96% Shares
BlackRock, Inc. $6,550,085 993,943 10.01% Shares
Octagon Capital Advisors LP $6,289,601 954,416 9.61% Shares
VANGUARD CAPITAL MANAGEMENT LLC $5,778,949 876,927 8.83% Shares
GEODE CAPITAL MANAGEMENT, LLC $3,513,176 532,950 5.37% Shares
STATE STREET CORP $1,617,199 245,402 2.47% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,214,445 184,286 1.86% Shares
NORTHERN TRUST CORP $1,117,249 169,537 1.71% Shares
SBI Securities Co., Ltd. $1,098,883 166,750 1.68% Shares
VANGUARD FIDUCIARY TRUST CO $995,571 151,073 1.52% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $816,850 123,953 1.25% Shares
GOLDMAN SACHS GROUP INC $568,289 86,235 0.87% Shares
Bank of New York Mellon Corp $413,523 62,750 0.63% Shares
MORGAN STANLEY $274,743 41,691 0.42% Shares
ALLIANCEBERNSTEIN L.P. $171,392 24,590 0.26% Shares
STRS OHIO $170,022 25,800 0.26% Shares
DIMENSIONAL FUND ADVISORS LP $166,516 25,268 0.25% Shares
Nuveen, LLC $161,488 24,505 0.25% Shares
UBS Group AG $123,649 18,763 0.19% Shares
MILLENNIUM MANAGEMENT LLC $121,836 18,488 0.19% Shares
DEUTSCHE BANK AG\ $118,218 17,939 0.18% Shares
RHUMBLINE ADVISERS $111,131 16,865 0.17% Shares
WELLS FARGO & COMPANY/MN $107,397 16,297 0.16% Shares
FMR LLC $98,679 14,974 0.15% Shares
ROYAL BANK OF CANADA $87,000 13,195 0.13% Shares
BANK OF AMERICA CORP /DE/ $82,539 12,525 0.13% Shares
Polymer Capital Management (US) LLC $77,630 11,780 0.12% Shares
Vanguard Global Advisers, LLC $65,788 9,983 0.10% Shares
Police & Firemen's Retirement System of New Jersey $59,382 9,011 0.09% Shares
CITIGROUP INC $56,582 8,586 0.09% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $55,659 8,446 0.09% Shares
JPMORGAN CHASE & CO $50,510 7,831 0.08% Shares
Russell Investments Group, Ltd. $24,930 3,783 0.04% Shares
BNP PARIBAS FINANCIAL MARKETS $22,973 3,486 0.04% Shares
BARCLAYS PLC $21,273 3,228 0.03% Shares
NEW YORK STATE COMMON RETIREMENT FUND $17,793 2,700 0.03% Shares
Tower Research Capital LLC (TRC) $16,271 2,469 0.02% Shares
Legal & General Group Plc $13,536 2,054 0.02% Shares
Ameritas Investment Partners, Inc. $4,501 683 0.01% Shares
Activest Wealth Management $3,512 533 0.01% Shares
Arax Advisory Partners $1,621 246 0.00% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,094 166 0.00% Shares
Sterling Capital Management LLC $1,061 161 0.00% Shares
GAMMA Investing LLC $962 146 0.00% Shares
CWM, LLC $725 104 0.00% Shares
Physician Wealth Advisors, Inc. $541 82 0.00% Shares
Bare Financial Services, Inc $521 79 0.00% Shares
GoalVest Advisory LLC $367 50 0.00% Shares
GoalVest Advisory LLC $330 50 0.00% Shares

Show all 62 institutional owners →

Activists & 5%+ owners 21 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Songjiang Ma, Yueying Zhu May 7, 2026 6.33% Amendment M&A / sale SEC
Ying Luo, Ping Lan May 6, 2026 8.60% Amendment M&A / sale SEC
GNI USA, Inc., GNI Group Ltd. ×4 filings May 6, 2026 69.10% Amendment M&A / sale SEC
Ying Luo (“Mr. Luo”), Ping Lan Sept. 6, 2024 · Initial filing Passive investment SEC
Songjiang Ma (“Mr. Ma”), Yueying Zhu Sept. 6, 2024 · Initial filing Passive investment SEC
GNI Group Ltd., GNI Hong Kong Limited, GNI USA, Inc. ×2 filings Oct. 31, 2023 · Initial filing · SEC
JDS1, LLC, CCUR Holdings, Inc., CIDM II, LLC, Julian D. Singer, David S. Oros ×13 filings Oct. 7, 2022 · Initial filing Passive investment SEC
JEC II Associates, LLC, The Heidi S. Shippell-Heiland 2008 Irrevocable Trust, Michael Torok ×4 filings Sept. 22, 2022 · Initial filing · SEC
Julian Singer, JDS1, LLC 2, CCUR Holdings, Inc., David S. Oros ×3 filings Jan. 27, 2022 · Initial filing · SEC
22NW Fund, LP, 22 NW, LP, 22NW Fund GP, LLC, 22NW GP, Inc., Aron R. English ×2 filings Aug. 5, 2020 · Initial filing · SEC
CCUR Holdings, Inc., Wayne Barr, Jr., JDS1, LLC, David S. Oros, Julian Singer ×3 filings Jan. 17, 2020 · Initial filing · SEC
Morgenthaler Management Partners VIII, LLC (“MMP VIII”), Morgenthaler Partners VIII, L.P. (“MP VIII”), Robert C. Bellas, Jr. (“Bellas”), Ralph E. Christoffersen (“Christoffersen”), John Lutsi (“Lutsi”), Gary J. Morgenthaler (“Morgenthaler”), Robert D. Pavey (“Pavey”), Gary R. Little (“Little”) Feb. 14, 2018 · Initial filing · SEC
HealthCare Ventures VIII, L.P., HealthCare Partners VIII, L.P., HealthCare Partners VIII, LLC, James H. Cavanaugh, Ph.D., Harold R. Werner, John W. Littlechild, Christopher Mirabelli, Ph.D., Augustine Lawlor ×2 filings Feb. 9, 2018 · Initial filing · SEC
May 23, 2017 · Initial filing · SEC
New Enterprise Associates 10, Limited Partnership, NEA Partners 10, Limited Partnership, Michael James Barrett, Peter J. Barris, Scott D. Sandell ×4 filings March 29, 2017 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 66 insiders · 26 officers · 32 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Ying Luo Chief Executive Officer June 8, 2026 A 2,565,226 0 2 $-82,927
Han Ying Chief Executive Officer Aug. 14, 2024 A · 0 0 $0
Charles C Wu Chief Executive Officer Nov. 20, 2023 A · 0 0 $0
Donald J Debethizy President and CEO May 4, 2012 A 798 0 0 $0
Thomas Wilson Eastling Chief Financial Officer May 4, 2026 A 15,000 0 0 $0
Ruoyu Chen Chief Financial Officer Jan. 7, 2026 A · 0 0 $0
Seline E. Miller SVP Finance; Interim CFO & PAO Aug. 31, 2023 D 0 0 0 $0
Clinton Musil Chief Financial Officer Feb. 8, 2021 A · 0 0 $0
Fletcher Payne Chief Financial Officer Aug. 12, 2019 A 3,744 0 0 $0
Mauri K Hodges Treasurer, CFO Aug. 14, 2015 A 1,159 0 0 $0
Alan A Musso SVP, Fin+Admin, CFO & Treas Oct. 17, 2014 A 57,799 0 0 $0
Songjiang Ma President May 28, 2025 S 2,806,084 0 0 $0
Weiguo Ye Chief Operating Officer June 18, 2026 M 700,000 0 16 $-869,947
Joshua Benjamin Bergmann GC and Corporate Secretary June 8, 2026 A · 0 0 $0
Grant E. Blouse Chief Scientific Officer Aug. 9, 2022 P 9,417 0 0 $0
Howard Levy Chief Medical Officer Aug. 9, 2021 P 639 0 0 $0
Veronica Cai Controller March 13, 2020 P 7,353 0 0 $0
Edwin Madison Chief Scientific Officer Oct. 22, 2015 A 31,008 0 0 $0
Patrick C. Rock Secretary, GC Aug. 14, 2015 A 45,000 0 0 $0
Steven M. Toler VP, Clin Pharm Sciences Oct. 17, 2014 A 46,000 0 0 $0
David A. Hosford VP, Clin Dev & Reg Affairs Jan. 23, 2014 A · 0 0 $0
Karen A Hicks VP, Human Resources Jan. 17, 2013 A 0 0 0 $0
Peter A Zorn SVP, Lgl Affrs, GC & Secretary Jan. 17, 2013 A 0 0 0 $0
Merouane Bencherif SVP and Senior Scien Fellow Jan. 17, 2013 A 15,938 0 0 $0
William S Caldwell SVP - Drug Discovery and Dev. Sept. 20, 2011 G 500 0 0 $0
Geoffrey C Dunbar SVP, Clin. Dev. & Reg. Affairs March 29, 2011 A 1,153 0 0 $0
Claire Weston Director Aug. 3, 2026 A · 0 0 $0
Maxwell Kirkby Director Aug. 3, 2026 A · 0 0 $0
Dan Weng Director June 10, 2026 A · 0 0 $0
Ping Zhang Director June 10, 2026 A · 0 0 $0
Rodney L Nussbaum Director June 10, 2026 A · 0 0 $0
Renate Parry Director June 10, 2026 A · 0 0 $0
Gordon Carmichael Director June 10, 2026 A · 0 0 $0
David M. Epstein Director June 10, 2026 A · 0 0 $0
Nassim Usman Director June 28, 2024 M 1,636 0 0 $0
Andrea Hunt Director Aug. 31, 2023 D 0 0 0 $0
Augustine Lawlor Director Aug. 31, 2023 D 0 0 0 $0
Geoffrey Ling M.D. Director Jan. 7, 2022 A 31,790 0 0 $0
Eddie Williams Director Jan. 7, 2022 A 34,804 0 0 $0
Errol B Desouza Director Oct. 1, 2021 A 29,801 0 0 $0
Jeanne Y Jew Director Sept. 9, 2021 A · 0 0 $0
Sharon Tetlow Director June 9, 2021 A 3,635 0 0 $0
John P Richard Director March 13, 2020 P 3,716 0 0 $0
Stephen A Hill Director Sept. 6, 2018 D 1,190 0 0 $0
Harold E Selick Director Jan. 16, 2018 A 16,614 0 0 $0
Jeff Himawan Director Aug. 20, 2015 J 1,179,352 0 0 $0
Alan W Dunton Director Aug. 14, 2015 A 10,000 0 0 $0
Charles A Blixt Director Aug. 14, 2015 A 10,000 0 0 $0
Julia R Brown Director Aug. 14, 2015 A 10,000 0 0 $0
SKALETSKY MARK B Director June 7, 2013 A 11,332 0 0 $0
Steven Burrill Director July 31, 2012 M 4,333 0 0 $0
Ralph Snyderman Director June 7, 2012 A 0 0 0 $0
Ann Hanham Director April 18, 2006 C 778,062 0 0 $0
GNI Hong Kong Ltd 10% owner Oct. 27, 2023 J 0 0 0 $0
Scott D. Sandell 10% owner Dec. 5, 2013 S 0 0 0 $0
Peter J Barris 10% owner Dec. 5, 2013 S 0 0 0 $0
James M Barrett 10% owner Dec. 3, 2013 M 0 0 0 $0
Richard C Kramlich 10% owner Nov. 19, 2012 X 5,333 0 0 $0
NEA Partners 10, Limited Partnership 10% owner Jan. 17, 2008 J 4,563,512 0 0 $0
Iii Eugene A Trainor 10% owner Jan. 17, 2008 J 4,563,512 0 0 $0
New Enterprise Associates 10, Limited Partnership 10% owner Jan. 17, 2008 J 4,563,512 0 0 $0
Mark W Perry 10% owner Jan. 17, 2008 J 4,563,512 0 0 $0
Charles W Newhall III 10% owner Jan. 17, 2008 J 4,563,512 0 0 $0
Peter Morris 10% owner Feb. 6, 2007 M 2,000 0 0 $0
Jeffrey P Brennan · Jan. 17, 2013 A 0 0 0 $0
Elaine V Jones · Nov. 29, 2007 X 27,500 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 11 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWO · iShares Trust 0.01% 120,729 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.00% 8,775 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.00% 387,159 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 238,693 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 614,654 SH Aug. 19, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.00% 104,607 SH Aug. 19, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 5,047 SH Aug. 19, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 13,494 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 805 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 320 NS July 31, 2026 N-PORT
IWN · iShares Trust · 41,397 SH Sept. 11, 2026 Daily

GYRE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 9 analysts BUY
Median target $18.00 +153.2%
3 33.3% Strong Buy
5 55.6% Buy
1 11.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

3 analysts · 2026-10-02

Mean target $18.67 +162.5%

← Below all targets Current price $7.11
Low$18.00 Mean$18.67 High$20.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
GYRE $645M 353.0 10.2% 8.5% 11.7% ·
ANNX $750M -3.7 · · -100.7% ·
AVTX $336M -3.1 -86.6% -132642.4% -83.4% ·
CADL $310M -7.8 · · -53.7% ·
GERN $845M -10.2 -60.2% · -34.4% ·
DSGN $567M -7.7 · · -32.8% ·
FDMT $432M -3.1 230194.6% -164.4% -30.2% ·
ACHV · -4.0 · · · ·
SLDB $445M -2.8 · · -79.5% ·
FTH · · · · · ·
VSTM $600M -2.6 209.1% -677.6% -449.2% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 7, 2026