DSGN Design Therapeutics, Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 3, 2026
$12.34
· of 52w range
· above low
· to high
$5.2852w low
$17.2552w high
Market Cap (MRQ)
$772M
P/E (TTM)
-10.5
EPS (TTM)
$-1.18
Revenue (TTM)
$0
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52W Range
$5–$17
Analyst Rating
BUY
Price Target
$21
P/E
-10.5
ROE
-34.1%
Net Profit Margin
·
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DSGN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$12.34
Market Cap (MRQ)
$772M
P/E (TTM)
-10.5
EPS (TTM)
$-1.18
Revenue (TTM)
$0
ROE (TTM)
-34.1%
52W Range
$5–$17
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue$02020-12-31 → 2025-12-31
EPS$-1.222021-12-31 → 2025-12-31
Free Cash Flow$-55M2021-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | DSGN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E (TTM) | -10.55Y avg ≈-10.7 | ≈-10.7 | · | · | |
| P/B (MRQ) | 3.85Y avg ≈1.9 | ≈1.9 | 3.0 | Overvalued | |
| Price / FCF (TTM) | -14.05Y avg ≈-14.1 | ≈-14.1 | · | · | |
| Price / Cash Flow (TTM) | -14.05Y avg ≈-14.5 | ≈-14.5 | · | · | |
| Price / Tangible Book | 3.55Y avg ≈1.9 | ≈1.9 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | DSGN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA (TTM) | -32.3%5Y avg ≈-20.5% | ≈-20.5% | -39.5% | Top tier | |
| ROE (TTM) | -34.1%5Y avg ≈-21.0% | ≈-21.0% | -49.6% | Top tier |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | DSGN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 18.95Y avg ≈36.0 | ≈36.0 | 8.9 | Strong liquidity | |
| Quick Ratio | 16.85Y avg ≈35.7 | ≈35.7 | 5.6 | Strong liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | DSGN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | · | |
| Revenue / Employee | ≈$0.00 | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
8.7%
Next Report
Nov 03, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 10, 2026 | $-0.32 | $-0.35 | 8.9% |
| March 31, 2026 | May 11, 2026 | $-0.29 | $-0.33 | 13.4% |
| Dec. 31, 2025 | $-0.27 | $-0.36 | 25.2% | |
| Sept. 30, 2025 | $-0.30 | $-0.35 | 14.3% | |
| June 30, 2025 | $-0.34 | $-0.34 | -1.0% | |
| March 31, 2025 | $-0.31 | $-0.29 | -8.5% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | · | · | · | $226.0K | |
| R&D Expense | $59M | $44M | $57M | $49M | $25M | $6M | |
| SG&A Expense | $20M | $18M | $21M | $19M | $11M | $2M | |
| Operating Expenses | $79M | $62M | $78M | $68M | $36M | $9M | |
| Operating Income | $-79M | $-62M | $-78M | $-68M | $-36M | $-8M | |
| Interest Income | $10M | $13M | $11M | · | · | · | |
| Other Non-op | · | · | $11M | $4M | $298.0K | $50.0K | |
| Income Tax | $0 | $0 | · | · | · | · | |
| Net Income | $-70M | $-50M | $-67M | $-63M | $-36M | $-8M | |
| EPS (Basic) | $-1.22 | $-0.88 | $-1.19 | $-1.14 | $-0.77 | · | |
| EPS (Diluted) | $-1.22 | $-0.88 | $-1.19 | $-1.14 | $-0.77 | · | |
| Shares (Basic) | 57,330,192 | 56,587,142 | 55,984,670 | 55,707,517 | 45,936,235 | · | |
| Shares (Diluted) | 57,330,192 | 56,587,142 | 55,984,670 | 55,707,517 | 45,936,235 | · | |
| EBITDA | $-79M | $-62M | $-78M | $-68M | $-36M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $17M | $23M | $21M | $26M | $299M | $2M | |
| Short-term Investments | $203M | $223M | $261M | $304M | $85M | $34M | |
| Prepaid Expense | $4M | $3M | $3M | $5M | $1M | $142.0K | |
| Other Current Assets | · | · | · | · | $7.0K | $25.0K | |
| Current Assets | $224M | $248M | $285M | $335M | $385M | $36M | |
| PP&E (Net) | $981.0K | $1M | $2M | $2M | $2M | $71.0K | |
| PP&E (Gross) | $3M | $3M | $3M | $2M | $2M | $76.0K | |
| Accum. Depreciation | $2M | $2M | $1M | $522.0K | $134.0K | $5.0K | |
| Total Assets | $226M | $252M | $290M | $341M | $391M | $37M | |
| Accounts Payable | $2M | $2M | $2M | $3M | $2M | $1M | |
| Accrued Liabilities | $11M | $6M | $8M | $8M | $4M | $931.0K | |
| Current Liabilities | $13M | $8M | $10M | $11M | $5M | $2M | |
| Capital Leases | $645.0K | $2M | $2M | $3M | $3M | · | |
| Other Non-current Liabilities | · | · | · | · | · | $145.0K | |
| Total Liabilities | $14M | $10M | $12M | $14M | $8M | $2M | |
| Common Stock | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $1.0K | |
| Retained Earnings | $-297M | $-227M | $-178M | $-111M | $-47M | $-12M | |
| AOCI | $403.0K | $475.0K | $62.0K | $-3M | $-244.0K | $156.0K | |
| Stockholders' Equity | $213M | $242M | $278M | $327M | $382M | $-11M | |
| Liabilities + Equity | $226M | $252M | $290M | $341M | $391M | $37M | |
| Shares Outstanding | 60,398,051 | 56,754,341 | 56,473,598 | 55,895,596 | 55,441,926 | 15,957,821 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $15M | $13M | $13M | $11M | $5M | $450.0K | |
| Deferred Tax | $0 | $0 | · | · | · | · | |
| Operating Cash Flow | $-54M | $-43M | $-59M | $-51M | $-29M | $-9M | |
| CapEx | $193.0K | $340.0K | $256.0K | $918.0K | $2M | $76.0K | |
| Investing Cash Flow | $23M | $44M | $53M | $-221M | $-54M | $-34M | |
| Stock Issued | $25M | $0 | · | · | · | · | |
| Net Stock Activity | $25M | · | · | · | · | · | |
| Financing Cash Flow | $26M | $513.0K | $724.0K | $235.0K | $379M | $45M | |
| Net Change in Cash | $-6M | $1M | $-5M | $-272M | $296M | $2M | |
| Taxes Paid | $0 | $0 | · | · | · | · | |
| Free Cash Flow | $-55M | $-43M | $-59M | $-52M | $-31M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -29.2% | -18.3% | -21.2% | -17.3% | -16.6% | · | |
| ROE | -32.8% | -20.1% | -23.8% | -18.9% | -9.2% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 17.1 | 29.3 | 29.6 | 31.1 | 73.0 | · | |
| Quick Ratio | 16.8 | 29.0 | 29.3 | 30.7 | 72.7 | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | · | · | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Book Value / Share | $3.52 | $4.27 | $4.92 | $5.86 | $6.89 | · | |
| Revenue / Share | $0.00 | $0.00 | · | · | · | · | |
| Cash Flow / Share | $-0.95 | $-0.76 | $-1.05 | $-0.92 | · | · | |
| Cash / Share | $0.28 | $0.40 | $0.38 | $0.47 | $5.39 | · | |
| EPS (TTM) | $-1.22 | $-0.88 | $-1.19 | $-1.14 | $-0.77 | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | · | · | · | · | |
| Net Income TTM | $-70M | $-50M | $-67M | $-63M | $-36M | · | |
| Market Cap | $567M | $350M | $150M | $573M | $1.19B | · | |
| P/E | -7.7 | -7.0 | -2.2 | -9.0 | -27.8 | · | |
| P/B | 2.7 | 1.4 | 0.5 | 1.8 | 3.1 | · | |
| P / Tangible Book | 2.7 | 1.4 | 0.5 | 1.8 | 3.1 | · | |
| P / Cash Flow | -10.4 | -8.1 | -2.6 | -11.2 | -40.4 | · | |
| P / FCF | -10.4 | -8.1 | -2.5 | -11.0 | -38.4 | · | |
| Earnings Yield | -13.0% | -14.3% | -44.9% | -11.1% | -3.6% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| R&D Expense | $16M | $14M | $13M | $15M | $16M | $15M | $12M | $12M | $11M | $10M | $11M | $13M | $17M | $16M | $14M | $14M | |
| SG&A Expense | $6M | $5M | $5M | $5M | $6M | $5M | $5M | $4M | $5M | $5M | $4M | $6M | $6M | $6M | $5M | $5M | |
| Operating Expenses | $22M | $20M | $18M | $19M | $22M | $20M | $17M | $16M | $15M | $14M | $15M | $19M | $23M | $22M | $19M | $19M | |
| Operating Income | $-22M | $-20M | $-18M | $-19M | $-22M | $-20M | $-17M | $-16M | $-15M | $-14M | $-15M | $-19M | $-23M | $-22M | $-19M | $-19M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | · | · | · | · | · | · | |
| Other Non-op | · | · | · | · | · | · | · | $3M | $3M | $3M | · | $3M | $3M | $2M | $2M | $1M | |
| Net Income | $-20M | $-18M | $-16M | $-17M | $-19M | $-18M | $-14M | $-13M | $-12M | $-11M | $-12M | $-16M | $-20M | $-19M | $-17M | $-18M | |
| EPS (Basic) | $-0.32 | $-0.29 | $-0.27 | $-0.30 | $-0.34 | $-0.31 | $-0.24 | $-0.23 | $-0.21 | $-0.20 | $-0.20 | $-0.28 | $-0.36 | $-0.35 | $-0.31 | $-0.32 | |
| EPS (Diluted) | $-0.32 | $-0.29 | $-0.27 | $-0.30 | $-0.34 | $-0.31 | $-0.24 | $-0.23 | $-0.21 | $-0.20 | $-0.20 | $-0.28 | $-0.36 | $-0.35 | $-0.31 | $-0.32 | |
| Shares (Basic) | 62,505,340 | 61,434,457 | · | 56,950,999 | 56,859,388 | 56,757,827 | · | 56,620,731 | 56,555,960 | 56,488,527 | · | 55,988,691 | 55,948,990 | 55,908,033 | · | 55,782,329 | |
| Shares (Diluted) | 62,505,340 | 61,434,457 | · | 56,950,999 | 56,859,388 | 56,757,827 | · | 56,620,731 | 56,555,960 | 56,488,527 | · | 55,988,691 | 55,948,990 | 55,908,033 | · | 55,782,329 | |
| EBITDA | $-22M | $-20M | · | $-19M | $-22M | $-20M | · | $-16M | $-15M | $-14M | · | $-19M | $-23M | $-22M | · | $-19M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $13M | $13M | $17M | $15M | $20M | $14M | $23M | $30M | $46M | $29M | $21M | $28M | $27M | $29M | $26M | $43M | |
| Short-term Investments | $194M | $210M | $203M | $191M | $197M | $216M | $223M | $224M | $215M | $241M | $261M | $263M | $276M | $287M | $304M | $302M | |
| Prepaid Expense | $5M | $4M | $4M | $3M | $4M | $4M | $3M | $3M | $4M | $3M | $3M | $4M | $3M | $4M | $5M | $4M | |
| Current Assets | $212M | $227M | $224M | $209M | $220M | $234M | $248M | $257M | $265M | $274M | $285M | $295M | $306M | $319M | $335M | $348M | |
| PP&E (Net) | $694.0K | $824.0K | $981.0K | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| PP&E (Gross) | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | |
| Accum. Depreciation | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $921.0K | $784.0K | $651.0K | $522.0K | $398.0K | |
| Total Assets | $215M | $230M | $226M | $212M | $223M | $237M | $252M | $262M | $270M | $279M | $290M | $300M | $312M | $325M | $341M | $355M | |
| Accounts Payable | $3M | $2M | $2M | $2M | $1M | $3M | $2M | $1M | $1M | $1M | $2M | $2M | $2M | $3M | $3M | $3M | |
| Accrued Liabilities | $8M | $8M | $11M | $9M | $8M | $5M | $6M | $6M | $5M | $6M | $8M | $10M | $10M | $6M | $8M | $8M | |
| Current Liabilities | $11M | $10M | $13M | $11M | $9M | $8M | $8M | $7M | $6M | $7M | $10M | $12M | $12M | $9M | $11M | $10M | |
| Capital Leases | $2M | $2M | $645.0K | $877.0K | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | |
| Total Liabilities | $13M | $12M | $14M | $12M | $10M | $10M | $10M | $9M | $8M | $9M | $12M | $15M | $15M | $12M | $14M | $14M | |
| Common Stock | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | |
| Retained Earnings | $-335M | $-315M | $-297M | $-281M | $-264M | $-245M | $-227M | $-214M | $-201M | $-189M | $-178M | $-166M | $-150M | $-130M | $-111M | $-93M | |
| AOCI | $-771.0K | $-268.0K | $403.0K | $358.0K | $305.0K | $450.0K | $475.0K | $914.0K | $-217.0K | $-167.0K | $62.0K | $-1M | $-2M | $-2M | $-3M | $-4M | |
| Stockholders' Equity | $202M | $218M | $213M | $200M | $213M | $228M | $242M | $252M | $261M | $270M | $278M | $285M | $297M | $313M | $327M | $341M | |
| Liabilities + Equity | $215M | $230M | $226M | $212M | $223M | $237M | $252M | $262M | $270M | $279M | $290M | $300M | $312M | $325M | $341M | $355M | |
| Shares Outstanding | 62,580,096 | 62,441,429 | 60,398,051 | 56,963,757 | 56,948,126 | 56,768,678 | 56,754,341 | 56,621,037 | 56,620,014 | 56,494,271 | 56,473,598 | 55,997,987 | 55,979,199 | 55,919,561 | 55,895,596 | 55,840,625 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $4M | $4M | $3M | $4M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $4M | $3M | $3M | $3M | |
| Operating Cash Flow | $-16M | $-16M | $-12M | $-11M | $-14M | $-17M | $-10M | $-10M | $-11M | $-12M | $-13M | $-15M | $-14M | $-17M | $-15M | $-14M | |
| CapEx | $21.0K | $0 | $34.0K | $0 | $87.0K | $72.0K | $0 | $-16.0K | $161.0K | $195.0K | $27.0K | $53.0K | $89.0K | $87.0K | $288.0K | $310.0K | |
| Investing Cash Flow | $15M | $-8M | $-12M | $7M | $20M | $8M | $2M | $-6M | $27M | $21M | $6M | $15M | $12M | $20M | $-1M | $-63M | |
| Stock Issued | $0 | $20M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | $0 | |
| Net Stock Activity | · | $20M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $605.0K | $20M | $25M | $37.0K | $361.0K | $23.0K | $263.0K | $1.0K | $229.0K | $20.0K | $501.0K | $13.0K | · | · | $130.0K | $151.0K | |
| Net Change in Cash | $137.0K | $-4M | $2M | $-5M | $6M | $-9M | $-8M | $-15M | $16M | $8M | $-7M | $745.0K | $-2M | $2M | $-16M | $-77M | |
| Free Cash Flow | · | $-16M | · | · | · | $-17M | · | · | · | $-13M | · | · | · | $-18M | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -9.2% | -7.5% | · | -7.2% | -7.8% | -6.9% | · | -4.6% | -4.1% | -3.7% | · | -4.8% | -5.9% | -5.5% | · | -4.7% | |
| ROE | -9.7% | -7.9% | · | -7.5% | -8.1% | -7.1% | · | -4.9% | -4.2% | -3.8% | · | -5.1% | -6.1% | -5.7% | · | -4.8% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 18.9 | 22.3 | · | 18.7 | 25.1 | 28.4 | · | 34.6 | 41.4 | 38.6 | · | 23.8 | 25.2 | 35.3 | · | 33.5 | |
| Quick Ratio | 18.5 | 21.9 | · | 18.4 | 24.7 | 27.9 | · | 34.2 | 40.8 | 38.2 | · | 23.5 | 25.0 | 34.9 | · | 33.1 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | 0.0 | · | · | · | 0.0 | · | · | · | · | · | · | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $3.23 | $3.49 | · | $3.51 | $3.74 | $4.01 | · | $4.46 | $4.61 | $4.77 | · | $5.09 | $5.30 | $5.59 | · | $6.11 | |
| Revenue / Share | · | $0.00 | · | · | · | $0.00 | · | · | · | · | · | · | · | · | · | · | |
| Cash Flow / Share | · | $-0.27 | · | · | · | $-0.30 | · | · | · | $-0.22 | · | · | · | $-0.31 | · | · | |
| Cash / Share | $0.21 | $0.20 | · | $0.26 | $0.35 | $0.24 | · | $0.54 | $0.81 | $0.52 | · | $0.50 | $0.49 | $0.52 | · | $0.76 | |
| EPS (TTM) | $-1.18 | $-1.20 | · | $-1.19 | $-1.12 | $-0.99 | · | $-0.84 | $-0.89 | $-1.04 | · | $-1.30 | $-1.34 | $-1.25 | · | $-1.03 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | · | · | · | · | · | $226.0K | $226.0K | $226.0K | · | $226.0K | $226.0K | $226.0K | · | $226.0K | |
| Net Income TTM | $-71M | $-70M | · | $-67M | $-63M | $-56M | · | $-48M | $-51M | $-59M | · | $-72M | $-74M | $-69M | · | $-57M | |
| Market Cap | $906M | $664M | · | $429M | $192M | $219M | · | $305M | $190M | $228M | · | $132M | $353M | $323M | · | $934M | |
| P/E | -12.3 | -8.9 | · | -6.3 | -3.0 | -3.9 | · | -6.4 | -3.8 | -3.9 | · | -1.8 | -4.7 | -4.6 | · | -16.2 | |
| P/S | · | · | · | · | · | · | · | 1347.9 | 839.3 | 1007.4 | · | 584.8 | 1560.5 | 1427.7 | · | 4131.2 | |
| P/B | 4.5 | 3.0 | · | 2.1 | 0.9 | 1.0 | · | 1.2 | 0.7 | 0.8 | · | 0.5 | 1.2 | 1.0 | · | 2.7 | |
| P / Tangible Book | 4.5 | 3.0 | · | 2.1 | 0.9 | 1.0 | · | 1.2 | 0.7 | 0.8 | · | 0.5 | 1.2 | 1.0 | · | 2.7 | |
| P / Cash Flow | · | -40.4 | · | · | · | -13.1 | · | · | · | -18.3 | · | · | · | -18.5 | · | · | |
| Earnings Yield | -8.2% | -11.3% | · | -15.8% | -33.2% | -25.7% | · | -15.6% | -26.6% | -25.8% | · | -55.1% | -21.3% | -21.7% | · | -6.2% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | · | · | · |
| Net Income | $-70M | $-50M | $-67M | $-63M | $-36M |
| Diluted EPS | $-1.22 | $-0.88 | $-1.19 | $-1.14 | $-0.77 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 17.1 | 29.3 | 29.6 | 31.1 | 73.0 |
| Quick Ratio | 16.8 | 29.0 | 29.3 | 30.7 | 72.7 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-55M | $-43M | $-59M | $-52M | $-31M |
Institutional owners (13F) 142 filers · $656.2M total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
142
Value held
$656.2M
New positions
32
Exited positions
16
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 32 (+10 vs prior Q) | 16 (+3 vs prior Q) | 60 (+4 vs prior Q) | 31 (+5 vs prior Q) | +7.0M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| SR One Capital Management, LP | $94,438,108 | 6,526,476 | 14.39% | Shares |
| Logos Global Management LP | $43,410,000 | 3,000,000 | 6.62% | Shares |
| BAKER BROS. ADVISORS LP | $38,756,882 | 2,678,430 | 5.91% | Shares |
| Driehaus Capital Management LLC | $38,506,334 | 2,661,115 | 5.87% | Shares |
| BlackRock, Inc. | $38,490,551 | 2,660,024 | 5.87% | Shares |
| Point72 Asset Management, L.P. | $34,242,575 | 2,366,453 | 5.22% | Shares |
| Trails Edge Capital Partners, LP | $28,958,550 | 2,001,282 | 4.41% | Shares |
| Frazier Life Sciences Management, L.P. | $26,188,587 | 1,809,854 | 3.99% | Shares |
| Vivo Capital, LLC | $23,338,706 | 1,612,903 | 3.56% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $22,732,688 | 1,571,022 | 3.46% | Shares |
| Caption Management, LLC | $21,705,000 | 1,500,000 | 3.31% | Call option |
| Caption Management, LLC | $16,178,878 | 1,118,098 | 2.47% | Shares |
| VANGUARD GROUP INC | $15,297,936 | 1,630,910 | 2.33% | Shares |
| Almitas Capital LLC | $14,859,142 | 1,026,893 | 2.26% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $13,871,597 | 958,417 | 2.11% | Shares |
| Sofinnova Investments, Inc. | $12,518,503 | 865,135 | 1.91% | Shares |
| FMR LLC | $11,235,405 | 776,462 | 1.71% | Shares |
| MORGAN STANLEY | $11,075,699 | 765,425 | 1.69% | Shares |
| STATE STREET CORP | $10,653,118 | 736,221 | 1.62% | Shares |
| Woodline Partners LP | $10,134,122 | 700,354 | 1.54% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $10,051,800 | 694,743 | 1.53% | Shares |
| GOLDMAN SACHS GROUP INC | $9,500,771 | 656,584 | 1.45% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $8,184,189 | 565,597 | 1.25% | Shares |
| Siren, L.L.C. | $7,570,878 | 523,212 | 1.15% | Shares |
| Qube Research & Technologies Ltd | $6,324,533 | 437,079 | 0.96% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $5,613,101 | 387,913 | 0.86% | Shares |
| KENNEDY CAPITAL MANAGEMENT LLC | $5,557,001 | 384,036 | 0.85% | Shares |
| NORTHERN TRUST CORP | $5,110,762 | 353,197 | 0.78% | Shares |
| ALGERT GLOBAL LLC | $4,284,350 | 296,085 | 0.65% | Shares |
| ACUTA CAPITAL PARTNERS, LLC | $4,088,701 | 282,564 | 0.62% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,925,190 | 271,264 | 0.60% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3,638,366 | 251,442 | 0.55% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,331,023 | 230,202 | 0.51% | Shares |
| PRUDENTIAL FINANCIAL INC | $3,243,740 | 224,170 | 0.49% | Shares |
| D. E. Shaw & Co., Inc. | $2,830,983 | 195,645 | 0.43% | Shares |
| Eversept Partners, LP | $2,749,300 | 190,000 | 0.42% | Shares |
| KVP Capital Advisors, LP | $2,676,950 | 185,000 | 0.41% | Shares |
| J. Goldman & Co LP | $2,557,862 | 176,770 | 0.39% | Shares |
| MILLENNIUM MANAGEMENT LLC | $2,137,422 | 147,714 | 0.33% | Shares |
| RAYMOND JAMES FINANCIAL INC | $2,004,399 | 138,521 | 0.31% | Shares |
| Balyasny Asset Management L.P. | $1,607,660 | 111,103 | 0.25% | Shares |
| Elmind Capital, LP | $1,561,313 | 107,900 | 0.24% | Shares |
| Nuveen, LLC | $1,515,501 | 104,734 | 0.23% | Shares |
| DAFNA Capital Management LLC | $1,484,622 | 102,600 | 0.23% | Shares |
| Bank of New York Mellon Corp | $1,332,238 | 92,069 | 0.20% | Shares |
| China Universal Asset Management Co., Ltd. | $1,301,432 | 89,940 | 0.20% | Shares |
| CITADEL ADVISORS LLC | $1,186,120 | 81,971 | 0.18% | Shares |
| SummitTX Capital, L.P. | $1,167,194 | 80,663 | 0.18% | Shares |
| AMERICAN CENTURY COMPANIES INC | $1,111,658 | 76,825 | 0.17% | Shares |
| Palumbo Wealth Management LLC | $1,038,136 | 71,744 | 0.16% | Shares |
Activists & 5%+ owners 3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| SR One Capital Fund I Aggregator, LP, SR One Capital Partners I, LP, SR One Capital Management, LLC, Simeon George ×2 filings | March 11, 2026 | 10.70% | Amendment | · | SEC |
| Logos Global Management LP, Logos Global Management GP LLC, Logos Global Master Fund LP, Logos GP LLC, Arsani William ×4 filings | Nov. 18, 2025 | 4.40% | Amendment | Board campaign | SEC |
| OR | April 9, 2021 | · | Initial filing | Passive investment | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 17 insiders · 6 officers · 11 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Pratik Shah | President, CEO and Chairperson | Jan. 2, 2026 A | 129,923 | 0 | 0 | $0 |
| Joao Siffert MD | President and CEO | Feb. 1, 2023 A | 132,619 | 0 | 0 | $0 |
| Sean Jeffries | Chief Operating Officer | Jan. 2, 2026 A | 3,050 | 0 | 0 | $0 |
| Julie Burgess | Chief Accounting Officer | Jan. 2, 2026 A | · | 0 | 0 | $0 |
| Chris Storgard | Chief Medical Officer | Jan. 2, 2026 A | · | 0 | 0 | $0 |
| Justin Thacker | Vice President, Finance | March 30, 2021 P | 17,500 | 0 | 0 | $0 |
| Justin D. Gover | Director | June 9, 2026 A | · | 0 | 0 | $0 |
| Heather A. Berger | Director | June 9, 2026 A | 1,300 | 0 | 0 | $0 |
| Simeon George | Director | June 9, 2026 A | 6,526,476 | 0 | 0 | $0 |
| Rodney W Lappe | Director | June 9, 2026 A | 133,024 | 0 | 0 | $0 |
| David Shapiro | Director | June 9, 2026 A | · | 0 | 0 | $0 |
| John P. Schmid | Director | June 9, 2026 A | 26,965 | 0 | 0 | $0 |
| Arsani William | Director | Aug. 13, 2025 S | 1,000,000 | 0 | 0 | $0 |
| Deepa Prasad | Director | June 10, 2025 A | 20,000 | 0 | 0 | $0 |
| Stella Xu | Director | May 31, 2023 A | 4,129,950 | 0 | 0 | $0 |
| Aseem Z. Ansari | 10% owner | Dec. 1, 2023 A | · | 0 | 0 | $0 |
| Quan Venture Fund II, L.P. | 10% owner | March 30, 2021 C | 4,720,830 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 28 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.74% | 28,333 NS | July 31, 2026 | N-PORT |
| IBRN · iShares Trust | 0.58% | 2,953 SH | Sept. 11, 2026 | Daily |
| IDNA · iShares Trust | 0.54% | 93,589 SH | Sept. 11, 2026 | Daily |
| DWAS · Invesco Exchange-Traded Fund Trust … | 0.39% | 130,512 SH | Oct. 2, 2026 | Daily |
| IWC · iShares Trust | 0.11% | 103,997 SH | Sept. 11, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.05% | 4,473 SH | Oct. 2, 2026 | Daily |
| IBB · iShares Trust | 0.04% | 290,492 SH | Sept. 11, 2026 | Daily |
| VFMO · VANGUARD WELLINGTON FUND | 0.03% | 39,047 SH | Aug. 19, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.03% | 32,807 SH | Aug. 19, 2026 | Daily |
| IWO · iShares Trust | 0.03% | 288,998 SH | Sept. 11, 2026 | Daily |
| IWM · iShares Trust | 0.02% | 801,435 SH | Sept. 11, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.01% | 156,210 NS | July 31, 2026 | N-PORT |
| RSSL · Global X Funds | 0.01% | 14,688 NS | July 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 373,755 SH | Aug. 19, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 177,257 SH | Aug. 19, 2026 | Daily |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0.01% | 1,536 SH | Oct. 2, 2026 | Daily |
| DFSU · Dimensional ETF Trust | 0.00% | 3,418 NS | July 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 4,864 NS | July 31, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 15,313 NS | July 31, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 32,522 NS | July 31, 2026 | N-PORT |
| IWV · iShares Trust | 0.00% | 9,154 SH | Sept. 3, 2026 | Daily |
| DFUS · Dimensional ETF Trust | 0.00% | 6,569 NS | July 31, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.00% | 154 NS | July 31, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1,161,075 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 2,331 SH | Aug. 19, 2026 | Daily |
| DFAT · Dimensional ETF Trust | 0.00% | 256 NS | July 31, 2026 | N-PORT |
| ISCB · iShares Trust | · | 1,744 SH | Sept. 11, 2026 | Daily |
| ISCV · iShares Trust | · | 9,099 SH | Sept. 11, 2026 | Daily |
DSGN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 13 analysts
BUY
Median target
$21.00
+70.2%
5 38.5%
Strong Buy
7 53.8%
Buy
1 7.7%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
6 analysts · 2026-09-29Mean target $21.00 +70.2%
← Below all targets
Current price $12.34
Low$20.00
Mean$21.00
High$22.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| DSGN | $567M | -7.7 | · | · | -32.8% | · |
| ANNX | $750M | -3.7 | · | · | -100.7% | · |
| AVTX | $336M | -3.1 | -86.6% | -132642.4% | -83.4% | · |
| GERN | $845M | -10.2 | -60.2% | · | -34.4% | · |
| CADL | $310M | -7.8 | · | · | -53.7% | · |
| GYRE | $645M | 353.0 | 10.2% | 8.5% | 11.7% | · |
| FDMT | $432M | -3.1 | 230194.6% | -164.4% | -30.2% | · |
| ACHV | · | -4.0 | · | · | · | · |
| SLDB | $445M | -2.8 | · | · | -79.5% | · |
| VSTM | $600M | -2.6 | 209.1% | -677.6% | -449.2% | · |
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Source: SEC 10-Q filed Aug 3, 2026