SLDB Solid Biosciences Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$9.03
Price · Aug 18, 2026
Fundamentals as of Aug 6, 2026

SLDB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$9.03
Market Cap
$713M
P/E (TTM)
-4.5
EPS (TTM)
$-1.99
Revenue (TTM)
Div Yield
ROE
-79.5%
Debt/Equity
52W Range
$4 – $11

SLDB Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
7-point trend, +8094000.00
2016-12-31 2022-12-31
EPS $-1.99
6-point trend, +92.2%
2020-12-31 2025-12-31
Free Cash Flow $-157M
7-point trend, -101.9%
2018-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
SLDB
Peer Median
P/E (TTM)
5-point trend, -9.5%
-4.5
P/B
5-point trend, -82.2%
4.0
3.4
Price / FCF
5-point trend, +92.3%
-4.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
SLDB
Peer Median
ROA
5-point trend, -131.4%
-82.8%
-31.3%
ROE
5-point trend, -137.8%
-79.5%
-38.1%
ROIC
-99.6%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
SLDB
Peer Median
Current Ratio
5-point trend, -34.9%
6.1
10.9
Quick Ratio
5-point trend, -64.5%
1.8

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
SLDB
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
SLDB
Peer Median
EPS (Diluted)
5-point trend, +80.4%
$-1.99

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
SLDB
Peer Median

SLDB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 19 analysts
  • Strong Buy 8 42.1%
  • Buy 10 52.6%
  • Hold 1 5.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

11 analysts · 2026-08-17
Median target $16.00 +77.2%
Mean target $17.64 +95.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.02%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.38 $-0.48 0.10%
March 31, 2026 $-0.52 $-0.44 -0.08%
Dec. 31, 2025 $-0.53 $-0.53 -0.00%
Sept. 30, 2025 $-0.48 $-0.45 -0.03%
June 30, 2025 $-0.42 $-0.51 0.09%
March 31, 2025 $-0.59 $-0.57 -0.02%
Dec. 31, 2024 $-1.00 $-0.82 -0.18%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
SLDB $445M -2.8 -79.5%
JANX $833M -7.5 -5.5% -1136.2% -11.7%
CLYM $191M -4.5 -34.6%
GERN $845M -10.2 -60.2% -34.4%
ANNX $750M -3.7 -100.7%
OLMA $2.03B -13.4 -39.4%
DSGN $567M -7.7 -32.8%
CADL $310M -7.8 -53.7%
FTH
IMMX $277M -5.9 -59.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for SLDB
Metric Trend 202520242023202220212020201920182017
Revenue 6-point trend, +8094000.00 · · · $8M $14M $0 $0 $0 $0
R&D Expense 9-point trend, +251.6% $140M $96M $77M $78M $59M $65M $95M $58M $40M
SG&A Expense 9-point trend, +160.0% $39M $33M $28M $29M $27M $22M $25M $18M $15M
Operating Expenses 9-point trend, +226.7% $179M $130M $104M $115M $86M $88M $119M $76M $55M
Operating Income 9-point trend, -226.7% $-179M $-130M $-104M $-106M $-72M $-88M $-119M $-76M $-55M
Interest Income 9-point trend, +4422.4% $10M $9M $8M $3M $64.0K $115.0K $2M $619.0K $219.0K
Other Non-op 9-point trend, -17.7% $824.0K $652.0K $1M $-381.0K $2.0K $1.0K $515.0K $270.0K $1M
Pretax Income 2-point trend, -39.8% $-174M $-125M · · · · · · ·
Income Tax Flat — no change across 8 periods $0 $0 $0 $0 $0 $0 $0 $0 ·
Net Income 9-point trend, -234.5% $-174M $-125M $-96M $-86M $-72M $-88M $-117M $-75M $-52M
EPS (Basic) 6-point trend, +92.2% $-1.99 $-3.06 $-4.83 $-10.10 $-10.14 $-25.50 · · ·
EPS (Diluted) 6-point trend, +92.2% $-1.99 $-3.06 $-4.83 $-10.10 $-10.14 $-25.50 · · ·
Shares (Basic) 6-point trend, +2427.2% 87,504,631 40,816,694 19,884,007 8,512,089 7,118,024 3,462,475 · · ·
Shares (Diluted) 6-point trend, +2427.2% 87,504,631 40,816,694 19,884,007 8,512,089 7,118,024 3,462,475 · · ·
EBITDA 7-point trend, -136.8% $-179M $-130M $-104M $-106M $-72M $-88M · $-76M ·
Balance Sheet 21
Annual Balance Sheet data for SLDB
Metric Trend 202520242023202220212020201920182017
Cash & Equivalents 9-point trend, +15.0% $60M $80M $74M $155M $119M $155M $76M $86M $52M
Short-term Investments 2-point trend, +112.2% · · · · · · · $36M $17M
Prepaid Expense 9-point trend, +993.0% $16M $8M $6M $6M $15M $4M $3M $6M $1M
Current Assets 9-point trend, +190.8% $205M $157M $130M $220M $223M $159M $86M $129M $71M
PP&E (Net) 9-point trend, +71.6% $4M $5M $7M $10M $6M $8M $12M $10M $2M
PP&E (Gross) 9-point trend, +525.9% $18M $18M $19M $21M $18M $17M $16M $12M $3M
Accum. Depreciation 9-point trend, +2715.5% $14M $13M $13M $11M $12M $9M $5M $2M $504.0K
Other Non-current Assets 8-point trend, +6.7% $223.0K $366.0K $209.0K $175.0K $94.0K $209.0K $209.0K $209.0K ·
Total Assets 9-point trend, +205.2% $233M $189M $165M $260M $232M $171M $103M $140M $76M
Accounts Payable 9-point trend, -36.4% $3M $4M $2M $3M $4M $3M $7M $4M $5M
Accrued Liabilities 9-point trend, +217.2% $19M $20M $10M $17M $10M $9M $9M $8M $6M
Current Liabilities 9-point trend, +197.0% $33M $30M $15M $23M $24M $24M $18M $12M $11M
Capital Leases 8-point trend, +2118.6% $19M $21M $23M $24M $275.0K $2M $4M $859.0K ·
Other Non-current Liabilities 3-point trend, -91.1% · · · $96.0K · $1M · $1M ·
Total Liabilities 9-point trend, +366.1% $53M $51M $38M $49M $24M $39M $23M $14M $11M
Common Stock 8-point trend, +125.7% $79.0K $40.0K $20.0K $20.0K $7.0K $87.0K $48.0K $35.0K ·
Retained Earnings 9-point trend, -670.8% $-958M $-783M $-659M $-563M $-477M $-405M $-316M $-199M $-124M
AOCI 9-point trend, +500.0% $52.0K $47.0K $15.0K $-68.0K $-45.0K $0 $1.0K $-5.0K $-13.0K
Stockholders' Equity 9-point trend, +403.8% $180M $137M $126M $212M $208M $132M $80M $125M $-59M
Liabilities + Equity 9-point trend, +205.2% $233M $189M $165M $260M $232M $171M $103M $140M $76M
Shares Outstanding 9-point trend, +78967888.00 78,967,888 40,468,141 20,386,606 19,556,732 7,356,017 84,893,994 45,987,571 35,432,460 0
Cash Flow 11
Annual Cash Flow data for SLDB
Metric Trend 202520242023202220212020201920182017
D&A 7-point trend, -42.1% $2M $2M $3M $2M $3M $4M $3M · ·
Stock-based Comp 9-point trend, +217.3% $17M $11M $8M $8M $13M $12M $14M $6M $5M
Restructuring 3-point trend, -103.2% · · $-63.0K $7M · $2M · · ·
Operating Cash Flow 9-point trend, -261.6% $-156M $-100M $-94M $-98M $-78M $-57M $-93M $-70M $-43M
CapEx 9-point trend, -49.3% $1M $654.0K $2M $3M $1M $899.0K $4M $8M $2M
Investing Cash Flow 9-point trend, -659.5% $-58M $-16M $10M $59M $-91M $7M $25M $-27M $10M
Stock Issued 5-point trend, -94.0% · · $3M $73M $135M $113M $49M · ·
Net Stock Activity 4-point trend, -97.4% · · $3M $73M $135M $113M · · ·
Financing Cash Flow 9-point trend, +152.3% $194M $122M $3M $75M $135M $129M $58M $132M $77M
Net Change in Cash 9-point trend, -145.8% $-20M $6M $-81M $36M $-34M $79M $-10M $35M $44M
Free Cash Flow 7-point trend, -101.9% $-157M $-101M $-96M $-101M $-79M $-57M · $-78M ·
Profitability 6
Annual Profitability data for SLDB
Metric Trend 202520242023202220212020201920182017
Operating Margin 2-point trend, -147.9% · · · -1315.2% -530.5% · · · ·
Net Margin 2-point trend, -100.4% · · · -1062.3% -530.0% · · · ·
EBITDA Margin 2-point trend, -147.9% · · · -1315.2% -530.5% · · · ·
ROA 7-point trend, -19.4% -82.8% -70.5% -45.2% -34.9% -35.8% -64.3% · -69.3% ·
ROE 7-point trend, -43.7% -79.5% -82.0% -70.9% -48.4% -33.5% -114.4% · -55.4% ·
ROIC -99.6% · · · · · · · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for SLDB
Metric Trend 202520242023202220212020201920182017
Current Ratio 7-point trend, -40.4% 6.1 5.2 8.9 9.8 9.4 6.5 · 10.3 ·
Quick Ratio 7-point trend, -74.1% 1.8 2.7 5.1 6.9 5.0 6.3 · 6.9 ·
Efficiency 1
Annual Efficiency data for SLDB
Metric Trend 202520242023202220212020201920182017
Asset Turnover 4-point trend, +0.03 · · · 0.0 0.1 0.0 · 0.0 ·
Per Share 5
Annual Per Share data for SLDB
Metric Trend 202520242023202220212020201920182017
Book Value / Share 7-point trend, -35.5% $2.28 $3.39 $6.20 $10.82 $1.89 $1.56 · $3.53 ·
Revenue / Share · · · $0.95 · · · · ·
Cash Flow / Share 4-point trend, +84.5% $-1.79 $-2.45 $-4.74 $-11.51 · · · · ·
Cash / Share 7-point trend, -68.9% $0.76 $1.98 $3.63 $7.95 $1.08 $1.82 · $2.44 ·
EPS (TTM) 6-point trend, +92.2% $-1.99 $-3.06 $-4.83 $-10.10 $-10.14 $-25.50 · · ·
Growth Rates 1
Annual Growth Rates data for SLDB
Metric Trend 202520242023202220212020201920182017
Revenue YoY · · · -40.6% · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for SLDB
Metric Trend 202520242023202220212020201920182017
Revenue TTM 9-point trend, +0.00 $0 $0 $0 $8M $14M $0 $0 $0 $0
Net Income TTM 9-point trend, -234.5% $-174M $-125M $-96M $-86M $-72M $-88M $-117M $-75M $-52M
Market Cap 7-point trend, -96.9% $445M $162M $125M $105M $2.90B $9.65B · $14.24B ·
P/E 6-point trend, +36.4% -2.8 -1.3 -1.3 -0.5 -2.6 -4.5 · · ·
P/S 2-point trend, -93.9% · · · 13.0 212.7 · · · ·
P/B 7-point trend, -97.8% 2.5 1.2 1.0 0.5 13.9 73.1 · 113.8 ·
P / Tangible Book 6-point trend, -96.6% 2.5 1.2 1.0 0.5 13.9 73.1 · · ·
P / Cash Flow 7-point trend, +98.6% -2.8 -1.6 -1.3 -1.1 -37.2 -170.5 · -202.9 ·
P / FCF 7-point trend, +98.5% -2.8 -1.6 -1.3 -1.0 -36.6 -167.9 · -182.7 ·
Earnings Yield 6-point trend, -57.3% -35.3% -76.5% -78.7% -187.7% -38.6% -22.4% · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $8M$14M
Operating Margin % -1315.2%-530.5%
Net Income $-174M$-125M$-96M$-86M$-72M
Diluted EPS $-1.99$-3.06$-4.83$-10.10$-10.14
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 6.15.28.99.89.4
Quick Ratio 1.82.75.16.95.0
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-157M$-101M$-96M$-101M$-79M

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Institutional owners (13F) 167 filers · $974.0M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
44 (+7 vs prior Q) 25 (+13 vs prior Q) 53 (0 vs prior Q) 39 (-1 vs prior Q) +6.6M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
RA CAPITAL MANAGEMENT, L.P. $120,240,899 12,036,126 12.34% Shares
PERCEPTIVE ADVISORS LLC $118,947,393 11,906,646 12.21% Shares
Bain Capital Life Sciences Investors, LLC $97,990,102 9,808,819 10.06% Shares
Siren, L.L.C. $76,827,146 7,690,405 7.89% Shares
FMR LLC $46,864,419 4,691,133 4.81% Shares
ARMISTICE CAPITAL, LLC $42,737,220 4,278,000 4.39% Shares
STATE STREET CORP $41,711,896 4,175,365 4.28% Shares
VANGUARD CAPITAL MANAGEMENT LLC $40,059,121 4,009,922 4.11% Shares
RTW INVESTMENTS, LP $38,890,331 3,892,926 3.99% Shares
Deep Track Capital, LP $35,614,969 3,565,062 3.66% Shares
JANUS HENDERSON GROUP PLC $28,877,004 4,010,695 2.96% Shares
CITADEL ADVISORS LLC $24,560,285 2,458,487 2.52% Shares
Alyeska Investment Group, L.P. $22,782,035 2,280,484 2.34% Shares
Vestal Point Capital, LP $21,578,400 2,160,000 2.22% Shares
AMERIPRISE FINANCIAL INC $20,575,205 2,059,578 2.11% Shares
Redmile Group, LLC $19,467,463 1,948,695 2.00% Shares
GEODE CAPITAL MANAGEMENT, LLC $16,645,589 1,665,937 1.71% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $15,049,995 1,506,506 1.55% Shares
GOLDMAN SACHS GROUP INC $14,106,819 1,412,094 1.45% Shares
DIMENSIONAL FUND ADVISORS LP $11,524,834 1,153,637 1.18% Shares
BLAIR WILLIAM & CO/IL $7,555,207 756,277 0.78% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $7,478,404 748,589 0.77% Shares
Woodline Partners LP $6,734,019 674,076 0.69% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $6,677,816 668,450 0.69% Shares
Birchview Capital, LP $6,655,298 666,196 0.68% Shares
MOORE CAPITAL MANAGEMENT, LP $6,028,685 603,472 0.62% Shares
Monashee Investment Management LLC $4,995,000 500,000 0.51% Shares
VANGUARD FIDUCIARY TRUST CO $4,942,353 494,730 0.51% Shares
Point72 Asset Management, L.P. $4,475,600 448,008 0.46% Shares
STEMPOINT CAPITAL LP $3,584,212 358,780 0.37% Shares
Boxer Capital Management, LLC $2,997,000 300,000 0.31% Shares
Ally Bridge Group (NY) LLC $2,557,030 255,959 0.26% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $2,441,566 244,401 0.25% Shares
J. Goldman & Co LP $2,419,218 242,164 0.25% Shares
D. E. Shaw & Co., Inc. $2,225,662 222,789 0.23% Shares
BANK OF AMERICA CORP /DE/ $2,040,777 204,282 0.21% Shares
UBS Group AG $1,881,587 188,347 0.19% Shares
ALGERT GLOBAL LLC $1,872,316 187,419 0.19% Shares
Balyasny Asset Management L.P. $1,780,747 178,253 0.18% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,628,740 163,037 0.17% Shares
Apis Capital Advisors, LLC $1,598,400 160,000 0.16% Shares
Soleus Capital Management, L.P. $1,498,500 150,000 0.15% Shares
CITIGROUP INC $1,437,471 143,891 0.15% Shares
Qube Research & Technologies Ltd $1,367,661 136,903 0.14% Shares
BlackRock, Inc. $1,293,865 129,516 0.13% Shares
Y-Intercept (Hong Kong) Ltd $1,097,761 109,886 0.11% Shares
Bank of New York Mellon Corp $1,081,707 108,279 0.11% Shares
BNP PARIBAS FINANCIAL MARKETS $1,081,038 108,212 0.11% Shares
Susquehanna Portfolio Strategies, LLC $1,071,717 107,279 0.11% Shares
RHUMBLINE ADVISERS $1,049,627 105,068 0.11% Shares
Fisher Asset Management, LLC $1,033,775 103,481 0.11% Shares
GOLDMAN SACHS GROUP INC $999,000 100,000 0.10% Call option
ALPS ADVISORS INC $998,161 99,916 0.10% Shares
XTX Topco Ltd $889,450 89,034 0.09% Shares
RENAISSANCE TECHNOLOGIES LLC $820,179 82,100 0.08% Shares
Verition Fund Management LLC $811,937 81,275 0.08% Shares
Quadrature Capital Ltd $782,117 78,290 0.08% Shares
Quantum Private Wealth, LLC $738,241 73,898 0.08% Shares
Rafferty Asset Management, LLC $717,072 71,779 0.07% Shares
Trexquant Investment LP $690,589 69,128 0.07% Shares
AMERICAN CENTURY COMPANIES INC $621,488 62,211 0.06% Shares
JANE STREET GROUP, LLC $617,242 61,786 0.06% Shares
TWO SIGMA INVESTMENTS, LP $606,443 60,705 0.06% Shares
WELLINGTON MANAGEMENT GROUP LLP $586,313 58,690 0.06% Shares
Vanguard Global Advisers, LLC $585,324 58,591 0.06% Shares
STATE OF WISCONSIN INVESTMENT BOARD $575,604 57,618 0.06% Shares
Knott David M Jr $561,518 56,208 0.06% Shares
BARCLAYS PLC $552,167 55,272 0.06% Shares
ALLIANCEBERNSTEIN L.P. $498,672 69,260 0.05% Shares
BANK OF NOVA SCOTIA $471,538 47,201 0.05% Shares
MetLife Investment Management, LLC $461,108 46,157 0.05% Shares
Virtus Investment Advisers, LLC $457,802 45,826 0.05% Shares
DeepCurrents Investment Group LLC $447,832 44,828 0.05% Shares
Ikarian Capital, LLC $429,130 42,956 0.04% Shares
Quantinno Capital Management LP $400,999 40,140 0.04% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $373,626 37,400 0.04% Call option
LOS ANGELES CAPITAL MANAGEMENT LLC $368,831 36,920 0.04% Shares
PROFUND ADVISORS LLC $365,065 36,543 0.04% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $361,998 36,236 0.04% Shares
Creative Planning $358,241 35,860 0.04% Shares
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC $332,577 33,291 0.03% Shares
ArchPoint Investors $312,947 31,326 0.03% Shares
Invesco Ltd. $308,891 30,920 0.03% Shares
CITADEL ADVISORS LLC $308,691 30,900 0.03% Call option
Engineers Gate Manager LP $288,861 28,915 0.03% Shares
HSBC HOLDINGS PLC $285,269 27,804 0.03% Shares
Atom Investors LP $271,548 27,182 0.03% Shares
Police & Firemen's Retirement System of New Jersey $231,868 23,210 0.02% Shares
SFMG, LLC $221,308 22,153 0.02% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $212,218 21,243 0.02% Shares
VANGUARD GROUP INC $205,307 36,402 0.02% Shares
BOOTHBAY FUND MANAGEMENT, LLC $199,291 19,949 0.02% Shares
AXQ CAPITAL, LP $197,193 19,739 0.02% Shares
CIBC Private Wealth Group LLC $188,802 30,600 0.02% Shares
Skopos Labs, Inc. $185,840 25,811 0.02% Shares
NEW YORK STATE COMMON RETIREMENT FUND $169,830 17,000 0.02% Shares
INTECH INVESTMENT MANAGEMENT LLC $162,857 16,302 0.02% Shares
Lido Advisors, LLC $159,700 15,986 0.02% Shares
China Universal Asset Management Co., Ltd. $156,523 15,668 0.02% Shares
VOYA INVESTMENT MANAGEMENT LLC $156,084 15,624 0.02% Shares

Company insiders 29 insiders · 13 officers · 14 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Alexander Cumbo President and CEO Jan. 29, 2026 A 235,405 0 4 $-983,959
Kevin Tan CFO & Treasurer Jan. 29, 2026 A 99,422 0 4 $-329,544
Jennifer Lynn Ziolkowski CFO, Treasurer & Asst. Secy Jan. 27, 2021 M 335,636 0 0 $0
David T Howton Chief Operating Officer Jan. 29, 2026 A 105,077 0 4 $-433,595
Pedro Alvaro Amorrortu Chief Operating Officer Jan. 23, 2019 A 162,746 0 0 $0
Gabriel Brooks Chief Medical Officer Jan. 29, 2026 A 89,466 0 3 $-280,978
Paul Herzich Chief Technology Officer Jan. 29, 2026 A 72,638 0 4 $-274,125
Jessie Hanrahan Chief Regulatory Officer Jan. 29, 2026 A 74,318 0 4 $-297,374
Jennifer Marlowe CSO Feb. 13, 2024 A 6,998 0 0 $0
Carl Ashley Morris Chief Scientific Officer Jan. 27, 2023 M 19,760 0 0 $0
Erin Powers Brennan Chief Legal Officer, Secretary May 2, 2022 A 0 0 $0
Lynette Herscha Chief Legal Officer July 27, 2020 M 160,859 0 0 $0
Jorge Armando Quiroz Chief Medical Officer Jan. 23, 2019 A 228,092 0 0 $0
Ian F Smith Director July 2, 2026 M 138,145 0 0 $0
Clare Kahn Director June 10, 2026 A 2,960 0 0 $0
Georgia Keresty Director June 10, 2026 A 0 0 $0
Lynne Marie Sullivan Director June 10, 2026 A 0 0 $0
Ilan Ganot Director June 10, 2026 A 27,474 0 5 $-82,352
Adam Leo Stone Director June 10, 2026 A 0 0 $0
Martin I Freed Director June 10, 2026 A 53,763 0 0 $0
Sukumar Nagendran Director June 10, 2026 A 34,258 0 0 $0
Adam Koppel Director Jan. 11, 2024 A 4,034,582 0 0 $0
Robert Luther Huffines Director Dec. 13, 2022 A 0 0 $0
Rajeev Shah Director June 16, 2021 A 8,709,882 0 0 $0
Matthew Bennett Arnold Director Dec. 10, 2020 A 3,933,429 0 0 $0
Juan Andrey Zarur Director Jan. 2, 2020 A 10,189 0 0 $0
Boxer Capital, LLC 10% owner March 28, 2019 S 3,473,272 0 0 $0
Gilad David Hayeem 10% owner Aug. 22, 2018 G 1,948,991 0 0 $0
Joel Solomon Zev Schneider March 14, 2022 S 236,270 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 4 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd., Perceptive Xontogeny Venture Fund, LP ×11 filings Aug. 14, 2026 11.20% Amendment SEC
RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×12 filings June 24, 2026 11.90% Amendment SEC
BCLS SB Investco, LP, Bain Capital Life Sciences Fund II, L.P., BCLS II Investco, LP, BCIP Life Sciences Associates, LP, BCLS II Equity Opportunities, LP, Bain Capital Life Sciences Opportunities IV, L.P. ×12 filings March 10, 2026 8.80% Amendment SEC
RA Capital Management, LLC, Peter Kolchinsky ×2 filings July 30, 2019 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 32 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IBRN · iShares Trust 0.69% 6,132 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.16% 266,224 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.06% 5,360 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.05% 580,274 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.03% 50,645 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.03% 35,267 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.03% 2,880 NS May 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.03% 96,646 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.02% 370,123 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.02% 2,011,320 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.02% 350,536 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 452,695 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.02% 41,246 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 263,560 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.01% 2,775 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 773,750 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 163,029 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.01% 2,170 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 18,153 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 2,193 NS May 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.00% 2,475 NS April 30, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.00% 7,422 NS April 30, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,366 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 55 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 19,273 NS April 30, 2026 N-PORT
ITOT · iShares Trust 0.00% 111,913 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 24,332 SH Aug. 8, 2026 Daily
DCOR · Dimensional ETF Trust 0.00% 2,692 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 17,135 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 3,148,576 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 5,707 SH Aug. 8, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 957 NS April 30, 2026 N-PORT