CRVS Corvus Pharmaceuticals, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$15.04
Price · Aug 18, 2026
Fundamentals as of Aug 6, 2026
52W Range
$5–$27
46% of range
Analyst Rating
BUY
14 analysts
Price Target
$33
+120% upside
P/E (TTM)
-28.4
ROE
-21.6%
Net Profit Margin
—

CRVS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$15.04
Market Cap
$1.12B
P/E (TTM)
-28.4
EPS (TTM)
$-0.53
Revenue (TTM)
—
Div Yield
—
ROE
-21.6%
Debt/Equity
—
52W Range
$5 – $27

CRVS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income —
EPS $-0.53
7-point trend, +66.7%
2019-12-31 → 2025-12-31
Free Cash Flow $-33M
7-point trend, +20.3%
2018-12-31 → 2025-12-31
Margins —

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CRVS
Peer Median
P/E (TTM)
5-point trend, -520.9%
-28.4
—
P/B
5-point trend, +713.8%
18.3
5.2
Price / FCF
5-point trend, -501.9%
-34.1
—

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CRVS
Peer Median
ROA
5-point trend, +50.8%
-21.8%
-44.7%
ROE
5-point trend, +49.5%
-21.6%
-51.5%
ROIC
5-point trend, -76.6%
-70.2%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CRVS
Peer Median
Current Ratio
5-point trend, -15.7%
6.2
9.5
Quick Ratio
5-point trend, -92.5%
0.5
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CRVS
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CRVS
Peer Median
EPS (Diluted)
5-point trend, +48.5%
$-0.53
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CRVS
Peer Median

CRVS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 5 35.7%
  • Buy 8 57.1%
  • Hold 1 7.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

7 analysts · 2026-08-16
Median target $32.00 +112.8%
Mean target $33.14 +120.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.06%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.19 $-0.16 -0.03%
March 31, 2026 $-0.15 $-0.15 -0.00%
Dec. 31, 2025 $-0.15 $-0.13 -0.02%
Sept. 30, 2025 $-0.12 $-0.14 0.02%
June 30, 2025 $-0.10 $-0.14 0.04%
March 31, 2025 $0.21 $-0.12 0.33%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CRVS $575M -14.5 — — -21.6% —
CGEM $624M -3.2 — — -44.0% —
NVAX $1.09B 2.6 64.7% 39.2% -977.1% —
INBX $1.15B -8.7 550.0% -10773.5% -365.9% —
GLUE $1.03B — 63.5% -31.2% -15.4% —
MGTX $645M -5.6 144.6% -140.3% 8062.2% —
MNKD $1.75B 283.5 22.2% 1.7% -11.1% —
REPL $633M -2.3 — — -146.2% —
VOR $506M -0.2 — — 83.4% —
SANA $1.09B -4.2 — — -172.3% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 12
Annual Income Statement data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
R&D Expense 11-point trend, +197.0% $34M $19M $17M $24M $29M $32M $38M $39M $46M $29M $11M
SG&A Expense 11-point trend, +282.6% $9M $8M $7M $8M $10M $12M $11M $11M $10M $8M $2M
Operating Expenses 11-point trend, +212.1% $43M $28M $23M $33M $39M $44M $49M $49M $57M $37M $14M
Operating Income 11-point trend, -212.1% $-43M $-28M $-23M $-33M $-39M $-44M $-49M $-49M $-57M $-37M $-14M
Pretax Income 11-point trend, +57.5% $-13M $-59M $-22M $-31M $-43M $-6M $-47M $-47M $-56M $-36M $-31M
Income Tax Flat — no change across 11 periods $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0
Net Income 11-point trend, +51.2% $-15M $-62M $-27M $-41M $-43M $-6M $-47M $-47M $-56M $-36M $-31M
EPS (Basic) 7-point trend, +88.1% $-0.19 $-1.02 $-0.56 $-0.89 $-1.03 $-0.20 $-1.59 · · · ·
EPS (Diluted) 7-point trend, +66.7% $-0.53 $-1.02 $-0.56 $-0.89 $-1.03 $-0.20 $-1.59 · · · ·
Shares (Basic) 7-point trend, +169.0% 78,964,842 60,985,165 48,025,274 46,553,511 41,854,110 29,478,878 29,349,810 · · · ·
Shares (Diluted) 7-point trend, +171.7% 79,742,685 60,985,165 48,025,274 46,553,511 41,854,110 29,478,878 29,349,810 · · · ·
EBITDA 8-point trend, +11.4% $-43M $-27M $-23M $-32M $-38M $-43M $-48M $-48M · · ·
Balance Sheet 23
Annual Balance Sheet data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, +11.5% $5M $9M $13M $13M $63M $16M $5M $39M $45M $5M $4M
Receivables 4-point trend, -93.7% $37.0K $75.0K $26.0K $588.0K · · · · · · ·
Prepaid Expense 11-point trend, +11.7% $1M $2M $781.0K $773.0K $1M $1M $1M $992.0K $1M $1M $1M
Other Current Assets 11-point trend, +69.7% $353.0K $548.0K $220.0K $102.0K $128.0K $406.0K $486.0K $265.0K $412.0K $772.0K $208.0K
Current Assets 11-point trend, -39.1% $58M $54M $28M $44M $71M $45M $79M $116M $91M $136M $96M
PP&E (Net) 11-point trend, -88.1% $220.0K $151.0K $236.0K $353.0K $451.0K $906.0K $1M $2M $3M $3M $2M
PP&E (Gross) 11-point trend, +44.9% $3M $5M $5M $5M $5M $5M $5M $5M $4M $4M $2M
Accum. Depreciation 11-point trend, +1862.2% $3M $5M $5M $5M $4M $4M $3M $2M $2M $729.0K $135.0K
Other Non-current Assets 10-point trend, -1.6% $855.0K $632.0K $89.0K $129.0K $236.0K $414.0K $513.0K $463.0K $869.0K $869.0K ·
Total Assets 11-point trend, -27.8% $71M $69M $46M $68M $109M $86M $84M $118M $95M $140M $98M
Accounts Payable 11-point trend, +58.2% $2M $3M $2M $2M $2M $3M $2M $2M $3M $2M $2M
Accrued Liabilities 3-point trend, +63.4% $6M $4M $4M · · · · · · · ·
Current Liabilities 11-point trend, +205.5% $9M $35M $7M $11M $10M $12M $10M $7M $9M $6M $3M
Capital Leases 6-point trend, -76.9% $534.0K $937.0K · $1M $3M $1M $2M · · · ·
Other Non-current Liabilities 4-point trend, +22.4% · · · · · · · $869.0K $971.0K $1M $710.0K
Total Liabilities 11-point trend, +162.3% $10M $36M $7M $12M $12M $13M $13M $8M $10M $7M $4M
Common Stock 10-point trend, +250.0% $7.0K $7.0K $5.0K $5.0K $5.0K $3.0K $3.0K $3.0K $2.0K $2.0K ·
Paid-in Capital 2-point trend, +10.1% $474M $431M · · · · · · · · ·
Retained Earnings 11-point trend, -1209.0% $-412M $-397M $-335M $-308M $-266M $-223M $-217M $-170M $-124M $-68M $-31M
AOCI 11-point trend, -1891.1% $-896.0K $-1M $-967.0K $-563.0K $2M $4.0K $29.0K $-34.0K $-41.0K $-39.0K $-45.0K
Stockholders' Equity 11-point trend, +296.8% $61M $33M $39M $56M $97M $72M $71M $110M $85M $133M $-31M
Liabilities + Equity 11-point trend, -27.8% $71M $69M $46M $68M $109M $86M $84M $118M $95M $140M $98M
Shares Outstanding 11-point trend, +5117.6% 74,696,629 67,899,779 49,038,582 46,553,511 46,553,511 28,372,634 27,953,233 29,323,930 21,041,250 20,922,428 1,431,615
Cash Flow 12
Annual Cash Flow data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
D&A 11-point trend, -29.1% $105.0K $85.0K $151.0K $367.0K $460.0K $632.0K $743.0K $847.0K $842.0K $594.0K $148.0K
Stock-based Comp 11-point trend, +1145.3% $5M $3M $2M $3M $4M $6M $7M $7M $6M $4M $428.0K
Other Non-cash 8-point trend, -1029.9% $-23M $34M $796.0K $11M $2M $-35M $1M $-2M · · ·
Operating Cash Flow 11-point trend, -189.5% $-33M $-25M $-24M $-27M $-37M $-35M $-37M $-41M $-46M $-28M $-11M
CapEx 10-point trend, -90.0% $174.0K · $34.0K $269.0K $5.0K $76.0K $25.0K $355.0K $266.0K $2M $2M
Investing Cash Flow 11-point trend, +91.5% $-8M $-27M $16M $-23M $22M $45M $3M $-30M $85M $-43M $-92M
Stock Issued 5-point trend, -77.0% · $16M · · $32M · · $65M $711.0K $71M ·
Net Stock Activity 3-point trend, -74.7% · $16M · · $32M · · $65M · · ·
Financing Cash Flow 11-point trend, -61.6% $36M $49M $8M $0 $62M $1M $24.0K $65M $1M $71M $95M
Net Change in Cash 11-point trend, +50.5% $-4M $-4M $-539.0K $-50M $47M $11M $-34M $-6M $40M $945.0K $-8M
Taxes Paid $0 · · · · · · · · · ·
Free Cash Flow 7-point trend, +20.3% $-33M · $-24M $-27M $-37M $-35M $-37M $-41M · · ·
Profitability 3
Annual Profitability data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
ROA 8-point trend, +50.5% -21.8% -108.9% -47.5% -46.5% -44.4% -7.1% -46.2% -44.1% · · ·
ROE 8-point trend, +47.2% -21.6% -277.0% -65.1% -68.4% -42.8% -10.5% -61.6% -41.0% · · ·
ROIC 8-point trend, -57.4% -70.2% -84.6% -60.5% -58.0% -39.8% -60.7% -68.7% -44.6% · · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 8-point trend, -62.3% 6.2 1.5 4.1 4.1 7.4 3.7 7.8 16.4 · · ·
Quick Ratio 8-point trend, -91.2% 0.5 0.2 1.8 1.2 6.5 1.4 0.5 5.6 · · ·
Per Share 4
Annual Per Share data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share 8-point trend, -78.2% $0.82 $0.48 $0.79 $1.21 $2.09 $2.54 $2.54 $3.76 · · ·
Cash Flow / Share 5-point trend, +53.1% $-0.41 $-0.42 $-0.50 $-0.58 $-0.88 · · · · · ·
Cash / Share 8-point trend, -95.4% $0.06 $0.13 $0.26 $0.28 $1.36 $0.58 $0.18 $1.34 · · ·
EPS (TTM) 7-point trend, +66.7% $-0.53 $-1.02 $-0.56 $-0.89 $-1.03 $-0.20 $-1.59 · · · ·
Valuation (TTM) 8
Annual Valuation (TTM) data for CRVS
Metric Trend 20252024202320222021202020192018201720162015
Net Income TTM 10-point trend, +58.0% $-15M $-62M $-27M $-41M $-43M $-6M $-47M $-47M $-56M $-36M ·
Market Cap 8-point trend, +434.4% $575M $363M $86M $40M $112M $101M $152M $108M · · ·
P/E 7-point trend, -324.6% -14.5 -5.2 -3.1 -1.0 -2.3 -17.8 -3.4 · · · ·
P/B 8-point trend, +863.4% 9.4 11.2 2.2 0.7 1.2 1.4 2.1 1.0 · · ·
P / Tangible Book 6-point trend, +571.2% 9.4 11.2 2.2 0.7 1.2 1.4 · · · · ·
P / Cash Flow 8-point trend, -567.9% -17.5 -14.3 -3.6 -1.5 -3.1 -2.9 -4.1 -2.6 · · ·
P / FCF 7-point trend, -570.1% -17.4 · -3.6 -1.4 -3.1 -2.9 -4.1 -2.6 · · ·
Earnings Yield 7-point trend, +76.5% -6.9% -19.1% -31.8% -104.7% -42.7% -5.6% -29.2% · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-15M$-62M$-27M$-41M$-43M
Diluted EPS $-0.53$-1.02$-0.56$-0.89$-1.03
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 6.21.54.14.17.4
Quick Ratio 0.50.21.81.26.5
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-33M—$-24M$-27M$-37M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 189 filers · $850.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
47 (-18 vs prior Q) 28 (+7 vs prior Q) 68 (+9 vs prior Q) 40 (+13 vs prior Q) +7.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
ORBIMED ADVISORS LLC $107,045,190 7,165,006 12.59% Shares
STATE STREET CORP $66,842,920 4,474,091 7.86% Shares
VANGUARD CAPITAL MANAGEMENT LLC $49,193,087 3,292,710 5.78% Shares
ADAMS STREET PARTNERS LLC $48,937,703 3,275,616 5.75% Shares
Vivo Capital, LLC $41,918,891 2,805,816 4.93% Shares
PERCEPTIVE ADVISORS LLC $39,851,569 2,667,441 4.69% Shares
Deep Track Capital, LP $37,229,569 2,491,939 4.38% Shares
BRAIDWELL LP $31,766,892 2,126,298 3.74% Shares
WELLINGTON MANAGEMENT GROUP LLP $28,099,301 1,880,810 3.30% Shares
Foresite Capital Management VI LLC $27,358,621 1,831,233 3.22% Shares
GEODE CAPITAL MANAGEMENT, LLC $23,775,864 1,590,939 2.80% Shares
Hood River Capital Management LLC $23,482,767 1,571,805 2.76% Shares
GOLDMAN SACHS GROUP INC $19,824,246 1,326,924 2.33% Shares
Boxer Capital Management, LLC $16,434,000 1,100,000 1.93% Shares
Catalio Capital Management, LP $16,148,467 1,080,888 1.90% Shares
MILLENNIUM MANAGEMENT LLC $15,656,896 1,047,985 1.84% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $12,172,365 814,750 1.43% Shares
TWO SIGMA INVESTMENTS, LP $11,731,008 785,208 1.38% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $11,205,000 750,000 1.32% Shares
Eversept Partners, LP $11,175,030 747,994 1.31% Shares
EMERALD ADVISERS, LLC $10,244,104 685,683 1.20% Shares
BANK OF AMERICA CORP /DE/ $10,073,400 674,257 1.18% Shares
DCF Advisers, LLC $9,524,250 637,500 1.12% Shares
Blue Owl Capital Holdings LP $9,092,484 608,600 1.07% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $8,739,900 585,000 1.03% Call option
EMERALD MUTUAL FUND ADVISERS TRUST $7,864,252 526,389 0.92% Shares
VANGUARD FIDUCIARY TRUST CO $7,776,688 520,528 0.91% Shares
RA CAPITAL MANAGEMENT, L.P. $6,723,000 450,000 0.79% Shares
Nextech Invest Ltd. $6,723,000 450,000 0.79% Shares
CITADEL ADVISORS LLC $6,675,192 446,800 0.78% Call option
CITADEL ADVISORS LLC $5,945,388 397,951 0.70% Shares
Jump Financial, LLC $4,682,196 313,400 0.55% Shares
BARCLAYS PLC $4,589,313 307,183 0.54% Shares
Trexquant Investment LP $4,427,424 296,347 0.52% Shares
DIADEMA PARTNERS LP $4,404,476 294,811 0.52% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $4,101,030 274,500 0.48% Put option
Polymer Capital Management (HK) LTD $3,939,110 263,662 0.46% Shares
Brevan Howard Capital Management LP $3,739,348 250,291 0.44% Shares
SPHERA FUNDS MANAGEMENT LTD. $3,659,717 244,961 0.43% Shares
Spruce Street Capital LP $3,459,880 231,585 0.41% Shares
SEB Asset Management AB $3,388,938 226,837 0.40% Shares
VICTORY CAPITAL MANAGEMENT INC $3,298,169 220,761 0.39% Shares
Connor, Clark & Lunn Investment Management Ltd. $3,253,185 217,750 0.38% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $3,109,298 208,119 0.37% Shares
CITADEL ADVISORS LLC $2,959,614 198,100 0.35% Put option
SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,848,177 190,641 0.33% Shares
Caption Management, LLC $2,838,600 190,000 0.33% Call option
F/m Investments LLC $2,497,445 167,165 0.29% Shares
JANE STREET GROUP, LLC $2,094,588 140,200 0.25% Call option
BlackRock, Inc. $2,085,251 139,575 0.25% Shares
DIADEMA PARTNERS LP $1,992,996 133,400 0.23% Call option
Swiss National Bank $1,889,910 126,500 0.22% Shares
Aquatic Capital Management LLC $1,762,920 118,000 0.21% Shares
ADAR1 Capital Management, LLC $1,749,489 117,101 0.21% Shares
CITIGROUP INC $1,664,555 111,416 0.20% Shares
Caption Management, LLC $1,664,316 111,400 0.20% Put option
MARSHALL WACE, LLP $1,501,082 100,474 0.18% Shares
SIMPLEX TRADING, LLC $1,379,604 92,343 0.16% Shares
ALLIANCEBERNSTEIN L.P. $1,322,845 90,420 0.16% Shares
RHUMBLINE ADVISERS $1,285,128 86,020 0.15% Shares
ALPS ADVISORS INC $1,274,980 85,340 0.15% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $1,238,631 82,907 0.15% Shares
Seven Fleet Capital Management LP $1,238,377 82,890 0.15% Shares
TD Asset Management Inc $1,233,984 82,596 0.15% Shares
Rafferty Asset Management, LLC $1,217,520 81,494 0.14% Shares
SEI INVESTMENTS CO $1,195,290 80,006 0.14% Shares
Avidity Partners Management LP $1,195,200 80,000 0.14% Shares
Persistent Asset Partners Ltd $1,117,452 74,796 0.13% Shares
Bank of New York Mellon Corp $1,094,011 73,227 0.13% Shares
Propel Bio Management, LLC $1,051,477 70,380 0.12% Shares
TOWERVIEW LLC $1,045,800 70,000 0.12% Shares
D. E. Shaw & Co., Inc. $967,768 64,777 0.11% Shares
Caption Management, LLC $956,668 64,034 0.11% Shares
JACKSON SQUARE CAPITAL, LLC $952,769 63,773 0.11% Shares
WELLS FARGO & COMPANY/MN $920,155 61,590 0.11% Shares
TUDOR INVESTMENT CORP ET AL $902,376 60,400 0.11% Call option
Ancora Advisors LLC $847,442 56,723 0.10% Shares
SEVEN GRAND MANAGERS, LLC $747,000 50,000 0.09% Shares
GROUP ONE TRADING LLC $721,482 48,292 0.08% Shares
Vanguard Global Advisers, LLC $712,459 47,688 0.08% Shares
VANGUARD ASSET MANAGEMENT, Ltd $660,632 44,219 0.08% Shares
Squarepoint Ops LLC $660,423 44,205 0.08% Shares
Y-Intercept (Hong Kong) Ltd $653,909 43,769 0.08% Shares
TEMA ETFS LLC $613,675 79,698 0.07% Shares
PROFUND ADVISORS LLC $613,197 41,044 0.07% Shares
MetLife Investment Management, LLC $592,341 39,648 0.07% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $559,159 37,427 0.07% Shares
AVITY INVESTMENT MANAGEMENT INC. $555,021 37,150 0.07% Shares
Engineers Gate Manager LP $538,124 36,019 0.06% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $494,365 33,090 0.06% Shares
STATE OF WISCONSIN INVESTMENT BOARD $414,719 27,759 0.05% Shares
Optimize Financial Inc $410,518 28,060 0.05% Shares
Virtus Investment Advisers, LLC $409,759 27,427 0.05% Shares
ACT CAPITAL MANAGEMENT, LLC $403,380 27,000 0.05% Shares
Invesco Ltd. $402,917 26,969 0.05% Shares
NEW YORK STATE COMMON RETIREMENT FUND $374,994 25,100 0.04% Shares
SIMON QUICK ADVISORS, LLC $373,500 25,000 0.04% Shares
PEAK6 LLC $352,584 23,600 0.04% Call option
WINTON GROUP Ltd $346,608 23,200 0.04% Shares
TUDOR INVESTMENT CORP ET AL $328,560 21,992 0.04% Shares

Company insiders 19 insiders · 8 officers · 10 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Richard A Miller MD President and CEO March 31, 2023 A 1,163,507 0 0 $0
Leiv Lea Chief Financial Officer Dec. 21, 2018 P 24,700 0 0 $0
Mehrdad Mobasher Chief Medical Officer Jan. 28, 2019 A — 0 0 $0
Daniel W. Hunt SVP, Chief Business Officer Dec. 12, 2018 A — 0 0 $0
William Benton Jones SVP, Pharmaceutical Development Dec. 12, 2018 A — 0 0 $0
Erik J. Verner V.P., Chemistry Research Dec. 12, 2018 A — 0 0 $0
Joseph J Buggy EVP Discovery Research Dec. 12, 2018 A — 0 0 $0
Jason V Coloma SVP, Chief Business Officer June 8, 2016 A — 0 0 $0
David Scott Moore Director June 11, 2026 A 21,700 1 0 $250,201
Richard Van Den Broek Director June 11, 2026 A — 0 0 $0
Linda S Grais Director June 11, 2026 A — 0 0 $0
Peter A. Thompson Director June 11, 2026 A 210,000 0 0 $0
Ian T Clark Director June 11, 2026 A — 0 0 $0
Steve E. Krognes Director June 20, 2019 A — 0 0 $0
Scott W Morrison Director June 20, 2019 A — 0 0 $0
Terry P Gould Director June 20, 2019 A 126,806 0 0 $0
ORBIMED ADVISORS LLC Director March 29, 2016 C 5,258,450 0 0 $0
Adams Street Partners, LLC 10% owner Aug. 11, 2022 A 126,806 0 0 $0
Novo Holdings A/S 10% owner July 8, 2020 S 1,389,498 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 5 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Adams Street Partners, LLC, Adams Street 2011 Direct Fund LP, Adams Street 2012 Direct Fund LP, Adams Street 2013 Direct Fund LP, Adams Street 2014 Direct Fund LP, Adams Street 2015 Direct Venture/Growth Fund LP, Adams Street 2016 Direct Venture/Growth Fund LP, Adams Street 2017 Direct Venture/Growth Fund LP, Adams Street 2018 Direct Venture/Growth Fund LP, Adams Street Venture/Growth Fund VI LP ×2 filings Feb. 5, 2026 3.90% Amendment — SEC
ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP V LLC ×13 filings Jan. 27, 2026 10.30% Amendment — SEC
Novo Holdings A/S ×2 filings July 9, 2020 — Initial filing — SEC
Novo Holdings A/S (formerly known as Novo A/S) Jan. 31, 2019 — Initial filing — SEC
Novo A/S March 30, 2016 — Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 36 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
LFSC · RBB Fund, Inc. 1.95% 165,305 NS May 31, 2026 N-PORT
BBC · ETFis Series Trust I 1.34% 32,976 NS April 30, 2026 N-PORT
IDNA · iShares Trust 0.96% 137,099 SH Aug. 8, 2026 Daily
CANC · Tema ETF Trust 0.76% 108,477 NS May 31, 2026 N-PORT
SBIO · ALPS ETF Trust 0.66% 86,347 NS May 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.35% 121,201 NS April 30, 2026 N-PORT
IWC · iShares Trust 0.21% 229,721 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.12% 156,977 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.08% 4,574 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.07% 467,057 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.06% 72,574 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.06% 620,432 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.05% 3,054 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.04% 29,277 NS May 31, 2026 N-PORT
PKW · Invesco Exchange-Traded Fund Trust 0.04% 46,535 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.03% 390,005 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.03% 1,735,953 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.03% 27,905 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.02% 3,029 NS May 31, 2026 N-PORT
TECB · iShares Trust 0.02% 6,211 SH Aug. 8, 2026 Daily
ISCV · iShares Trust 0.02% 8,903 SH Aug. 8, 2026 Daily
ISCB · iShares Trust 0.01% 2,886 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.01% 2,369 NS May 31, 2026 N-PORT
SMLF · iShares Trust 0.01% 35,858 SH Aug. 8, 2026 Daily
ISCG · iShares Trust 0.01% 7,654 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 844,478 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 189,601 SH Aug. 8, 2026 Daily
WSML · iShares Trust 0.01% 4,445 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.01% 2,398 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 60 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.00% 27,317 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 1,515 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 109,007 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 22,441 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,374,106 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 5,593 SH Aug. 8, 2026 Daily