MNPR Monopar Therapeutics Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$117.66
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026

MNPR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$117.66
Market Cap
P/E (TTM)
EPS (TTM)
Revenue (TTM)
$0
Div Yield
ROE
Debt/Equity
52W Range
$29 – $125

MNPR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $0
Flat — no change across 7 periods
2016-12-31 2025-12-31
EPS
Free Cash Flow
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
MNPR
Peer Median

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
MNPR
Peer Median

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
MNPR
Peer Median

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
MNPR
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
MNPR
Peer Median

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
MNPR
Peer Median

MNPR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 19 analysts
  • Strong Buy 4 21.1%
  • Buy 14 73.7%
  • Hold 1 5.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

13 analysts · 2026-08-16
Median target $128.00 +8.8%
Mean target $124.77 +6.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.28%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.46 $-0.85 0.39%
Dec. 31, 2025 $-0.64 $-0.50 -0.14%
Sept. 30, 2025 $-0.48 $-0.44 -0.04%
June 30, 2025 $-0.35 $-0.48 0.13%
March 31, 2025 $-0.38 $-0.69 0.31%
Dec. 31, 2024 $-2.75 $-0.43 -2.3%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
MNPR
IMMX $277M -5.9 -59.8%
RIGL $784M 2.2 64.1% 124.7% 155.1%
AURA $347M -3.1 -29.7% -1601.4% -68.2%
FDMT $432M -3.1 230194.6% -164.4% -30.2%
ACHV -4.0
CTMX $725M -44.8% -22.8% -15.9%
NGNE $319M -4.9 -33.6%
STTK $231M -5.2 -82.5% -4880.9% -70.0%
RGNX $733M -3.8 104.5% -113.8% -122.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 12
Annual Income Statement data for MNPR
Metric Trend 202520242023202220212020201920182017
Revenue Flat — no change across 6 periods $0 $0 $0 · · · $0 $0 $0
R&D Expense 9-point trend, +958.9% $10M $13M $6M $8M $6M $4M $2M $2M $935.3K
SG&A Expense 9-point trend, +483.1% $7M $3M $3M $3M $3M $2M $2M $2M $1M
Operating Expenses 9-point trend, +0.6% $17M $16M $9M $11M $9M $7M $4M $3M $17M
Operating Income 9-point trend, -0.6% $-17M $-16M $-9M $-11M $-9M $-7M $-4M $-3M $-17M
Interest Income 3-point trend, +596.3% $3M $404.0K $429.0K · · · · · ·
Pretax Income 5-point trend, +17.1% $-14M $-16M $-8M · · · · $-3M $-17M
Income Tax 9-point trend, +122.5% $800 $800 $800 $800 $0 $18.4K $0 $-70.8K $-3.6K
Net Income 9-point trend, +17.1% $-14M $-16M $-8M $-11M $-9M $-6M $-4M $-3M $-17M
EPS (Basic) 4-point trend, -122.9% $-1.85 $-4.11 $-3.04 $-0.83 · · · · ·
Shares (Basic) 5-point trend, -40.6% 7,411,121 3,790,202 2,764,790 12,718,166 12,471,217 · · · ·
EBITDA 7-point trend, -375.0% · $-16M $-9M $-11M $-9M $-7M $-4M $-3M ·
Balance Sheet 16
Annual Balance Sheet data for MNPR
Metric Trend 202520242023202220212020201920182017
Cash & Equivalents 9-point trend, +588.4% $62M $46M $7M $8M $20M $17M $13M $7M $9M
Other Current Assets 7-point trend, +305.7% $63.7K $78.9K $66.4K $46.0K $217.7K $62.7K $15.7K · ·
Current Assets 9-point trend, +1438.3% $140M $60M $7M $13M $21M $17M $13M $7M $9M
Other Non-current Assets 4-point trend, -100.0% · · · · $0 $68.9K $122.4K $65.7K ·
Total Assets 9-point trend, +1316.9% $141M $60M $7M $13M $21M $17M $13M $7M $10M
Accounts Payable 9-point trend, +777.1% $3M $2M $2M $3M $2M $1M $724.2K $399.6K $311.9K
Current Liabilities 9-point trend, +777.1% $3M $5M $2M $3M $2M $1M $724.2K $399.6K $311.9K
Capital Leases 5-point trend, +154920.00 $154.9K $0 $0 $8.4K $0 · · · ·
Total Liabilities 9-point trend, +826.7% $3M $5M $2M $3M $2M $1M $724.2K $399.6K $311.9K
Common Stock 9-point trend, -28.0% $6.7K $6.1K $3.0K $12.9K $12.6K $11.5K $10.6K $9.3K $9.3K
Paid-in Capital 6-point trend, +120.7% · · · $62M $60M $48M $39M $29M $28M
Retained Earnings 9-point trend, -385.7% $-90M $-76M $-60M $-52M $-41M $-32M $-26M $-22M $-18M
AOCI 9-point trend, +131389.00 $131.4K $36.0K $-14.1K $8.9K $-3.2K $-7.9K $-11.0K $-2.4K $0
Stockholders' Equity 9-point trend, +1332.8% $138M $55M $6M $10M $19M $16M $13M $7M $10M
Liabilities + Equity 9-point trend, +1316.9% $141M $60M $7M $13M $21M $17M $13M $7M $10M
Shares Outstanding 9-point trend, -28.0% 6,692,140 6,102,560 2,980,900 12,946,573 12,598,125 11,453,465 10,587,632 9,291,421 9,291,421
Cash Flow 10
Annual Cash Flow data for MNPR
Metric Trend 202520242023202220212020201920182017
Stock-based Comp 4-point trend, +194.8% $5M $1M $2M $2M · · · · ·
Deferred Tax 9-point trend, +0.00 $0 $0 $0 $0 $0 $0 $0 $-71.6K $0
Operating Cash Flow 9-point trend, -364.4% $-12M $-6M $-8M $-7M $-7M $-5M $-3M $-3M $-3M
Investing Cash Flow 5-point trend, -63453114.00 $-63M $-14M $5M $-5M $0 · · · ·
Stock Issued 8-point trend, -100.0% $0 $4M $2M $109.3K · $8M $0 $0 $5M
Stock Repurchased 2-point trend, +34999957.00 $35M $0 · · · · · · ·
Net Stock Activity 4-point trend, +4202245.00 · $4M $2M · · $8M · $0 ·
Financing Cash Flow 9-point trend, +860.3% $92M $59M $2M $32.9K $11M $8M $9M $-206.3K $10M
Net Change in Cash 9-point trend, +131.8% $16M $39M $-920.1K $-12M $4M $4M $6M $-3M $7M
Taxes Paid 3-point trend, -100.0% · · · · $0 $-11.1K $53 · ·
Profitability 6
Annual Profitability data for MNPR
Metric Trend 202520242023202220212020201920182017
Operating Margin 3-point trend, -524.3% · · · -49611.0% -37992.2% -7947.2% · · ·
Net Margin 3-point trend, -543.2% · · · -49511.0% -37892.2% -7697.7% · · ·
EBITDA Margin 3-point trend, -524.3% · · · -49611.0% -37992.2% -7947.2% · · ·
ROA 7-point trend, -23.1% · -46.1% -81.7% -62.3% -48.7% -41.7% -40.9% -37.4% ·
ROE 7-point trend, -16.7% · -52.0% -137.8% -93.1% -45.3% -38.0% -49.0% -44.5% ·
ROIC 2-point trend, +39.0% · -29.4% · · · · · -48.1% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for MNPR
Metric Trend 202520242023202220212020201920182017
Current Ratio 5-point trend, -77.2% · · 4.2 4.2 · 14.3 18.3 18.3 ·
Quick Ratio 5-point trend, -76.0% · · 4.1 2.6 · 14.2 18.2 17.3 ·
Efficiency 1
Annual Efficiency data for MNPR
Metric Trend 202520242023202220212020201920182017
Asset Turnover 7-point trend, +0.00 · 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ·
Per Share 2
Annual Per Share data for MNPR
Metric Trend 202520242023202220212020201920182017
Book Value / Share 7-point trend, +1111.2% · $9.02 $0.37 $0.78 $1.50 $1.37 $1.19 $0.74 ·
Cash / Share 7-point trend, +912.1% · $7.51 $0.49 $0.63 $1.61 $1.46 $1.25 $0.74 ·
Valuation (TTM) 6
Annual Valuation (TTM) data for MNPR
Metric Trend 202520242023202220212020201920182017
Revenue TTM Flat — no change across 9 periods $0 $0 $0 $0 $0 $0 $0 $0 $0
Net Income TTM 9-point trend, +17.1% $-14M $-16M $-8M $-11M $-9M $-6M $-4M $-3M $-17M
Market Cap 6-point trend, -84.7% · $134M $25M $153M $202M $350M $879M · ·
P/B 6-point trend, -96.5% · 2.4 4.5 15.2 10.7 22.3 69.6 · ·
P / Tangible Book 6-point trend, -85.8% 3.2 2.4 4.5 15.2 10.7 22.3 · · ·
P / Cash Flow 6-point trend, +92.8% · -21.0 -3.2 -21.2 27.6 -75.2 -291.2 · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0$0$0
Operating Margin % -49611.0%-37992.2%
Net Income $-14M$-16M$-8M$-11M$-9M
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 4.24.2
Quick Ratio 4.12.6

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Institutional owners (13F) 100 filers · $468.8M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
35 (+20 vs prior Q) 14 (+5 vs prior Q) 26 (-1 vs prior Q) 24 (+2 vs prior Q) -997K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
JANUS HENDERSON GROUP PLC $72,062,327 1,317,410 15.37% Shares
RA CAPITAL MANAGEMENT, L.P. $61,776,696 667,207 13.18% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $29,975,550 323,745 6.39% Shares
Saturn V Capital Management LP $28,885,858 311,976 6.16% Shares
Siren, L.L.C. $25,010,226 270,118 5.33% Shares
ADAR1 Capital Management, LLC $20,147,121 217,595 4.30% Shares
Polar Capital Holdings Plc $19,857,685 214,469 4.24% Shares
VANGUARD CAPITAL MANAGEMENT LLC $19,417,141 209,711 4.14% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $19,369,365 209,195 4.13% Shares
TCG Crossover Management, LLC $18,826,047 203,327 4.02% Shares
ORBIMED ADVISORS LLC $14,575,796 157,423 3.11% Shares
Candriam S.C.A. $13,258,989 143,339 2.83% Shares
Balyasny Asset Management L.P. $12,457,336 134,543 2.66% Shares
Alyeska Investment Group, L.P. $9,259,000 100,000 1.97% Shares
GEODE CAPITAL MANAGEMENT, LLC $8,975,407 96,907 1.91% Shares
STATE STREET CORP $8,569,297 92,551 1.83% Shares
Vivo Capital, LLC $8,379,395 90,500 1.79% Shares
Driehaus Capital Management LLC $7,781,264 84,040 1.66% Shares
Vestal Point Capital, LP $7,011,563 75,727 1.50% Shares
WELLINGTON MANAGEMENT GROUP LLP $6,686,294 72,214 1.43% Shares
Longaeva Partners L.P. $5,169,670 55,834 1.10% Shares
MILLENNIUM MANAGEMENT LLC $4,658,295 50,311 0.99% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $4,519,873 48,816 0.96% Shares
Ikarian Capital, LLC $4,431,450 47,861 0.95% Shares
CITADEL ADVISORS LLC $3,426,200 37,004 0.73% Shares
NEUBERGER BERMAN GROUP LLC $3,394,535 36,662 0.72% Shares
Bank of New York Mellon Corp $3,174,356 34,284 0.68% Shares
STEMPOINT CAPITAL LP $2,789,274 30,125 0.59% Shares
VANGUARD FIDUCIARY TRUST CO $2,618,445 28,280 0.56% Shares
UBS Group AG $2,513,078 27,142 0.54% Shares
VANGUARD GROUP INC $1,873,914 28,697 0.40% Shares
AMERIPRISE FINANCIAL INC $1,648,102 17,800 0.35% Shares
BOOTHBAY FUND MANAGEMENT, LLC $1,360,055 14,689 0.29% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,291,908 13,953 0.28% Shares
Ishara Investments LP $1,138,857 12,300 0.24% Shares
TWO SIGMA INVESTMENTS, LP $1,134,413 12,252 0.24% Shares
Trexquant Investment LP $1,111,450 12,004 0.24% Shares
GOLDMAN SACHS GROUP INC $738,498 7,976 0.16% Shares
XTX Topco Ltd $605,168 6,536 0.13% Shares
Nuveen, LLC $553,688 5,980 0.12% Shares
RHUMBLINE ADVISERS $521,271 5,630 0.11% Shares
GERBER, LLC $518,597 5,601 0.11% Shares
Virtus Investment Advisers, LLC $506,838 5,474 0.11% Shares
RAYMOND JAMES FINANCIAL INC $506,838 5,474 0.11% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $490,727 5,300 0.10% Shares
Aquatic Capital Management LLC $354,342 3,827 0.08% Shares
WELLS FARGO & COMPANY/MN $352,953 3,812 0.08% Shares
Engineers Gate Manager LP $322,121 3,479 0.07% Shares
BANK OF AMERICA CORP /DE/ $300,918 3,250 0.06% Shares
MetLife Investment Management, LLC $269,252 2,908 0.06% Shares
ALLIANCEBERNSTEIN L.P. $260,800 4,760 0.06% Shares
EP Wealth Advisors, LLC $241,012 2,603 0.05% Shares
Entropy Technologies, LP $240,734 2,600 0.05% Shares
WINTON GROUP Ltd $231,475 2,500 0.05% Shares
GABELLI FUNDS LLC $231,475 2,500 0.05% Shares
AMERICAN CENTURY COMPANIES INC $228,605 2,469 0.05% Shares
NEW YORK STATE COMMON RETIREMENT FUND $222,216 2,400 0.05% Shares
Martin Investment Management, LLC $215,457 2,327 0.05% Shares
Schonfeld Strategic Advisors LLC $213,882 2,310 0.05% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $192,217 2,076 0.04% Shares
CITIGROUP INC $169,255 1,828 0.04% Shares
Invesco Ltd. $165,088 1,783 0.04% Shares
DIADEMA PARTNERS LP $150,922 1,630 0.03% Shares
Vanguard Global Advisers, LLC $143,792 1,553 0.03% Shares
Quarry LP $139,070 1,502 0.03% Shares
Police & Firemen's Retirement System of New Jersey $135,922 1,468 0.03% Shares
AlphaQuest LLC $129,490 1,983 0.03% Shares
MEEDER ASSET MANAGEMENT INC $128,608 1,389 0.03% Shares
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $124,996 1,350 0.03% Shares
BlackRock, Inc. $115,460 1,247 0.02% Shares
BNP PARIBAS FINANCIAL MARKETS $68,609 741 0.01% Shares
BARCLAYS PLC $66,387 717 0.01% Shares
NORTHERN TRUST CORP $65,554 708 0.01% Shares
NewEdge Advisors, LLC $55,554 600 0.01% Shares
FMR LLC $49,073 530 0.01% Shares
Legal & General Group Plc $43,054 465 0.01% Shares
Persistent Asset Partners Ltd $38,147 412 0.01% Shares
Ameritas Investment Partners, Inc. $37,869 409 0.01% Shares
Tower Research Capital LLC (TRC) $31,944 345 0.01% Shares
Creative Planning $31,295 338 0.01% Shares
JPMORGAN CHASE & CO $18,628 197 0.00% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $13,533 247 0.00% Shares
ROYAL BANK OF CANADA $13,000 136 0.00% Shares
Allworth Financial LP $10,278 111 0.00% Shares
Russell Investments Group, Ltd. $9,815 106 0.00% Shares
C M BIDWELL & ASSOCIATES LTD $8,703 94 0.00% Shares
DEUTSCHE BANK AG\ $8,333 90 0.00% Shares
Sterling Capital Management LLC $6,666 72 0.00% Shares
MERCER GLOBAL ADVISORS INC /ADV $3,333 36 0.00% Shares
Global Retirement Partners, LLC $2,963 32 0.00% Shares
GAMMA Investing LLC $2,315 25 0.00% Shares
Farther Finance Advisors, LLC $2,222 24 0.00% Shares
CWM, LLC $822 15 0.00% Shares
GSA CAPITAL PARTNERS LLP $697 7,532 0.00% Shares
MORGAN STANLEY $556 6 0.00% Shares
US BANCORP \DE\ $556 6 0.00% Shares
PNC Financial Services Group, Inc. $556 6 0.00% Shares
PRICE T ROWE ASSOCIATES INC /MD/ $343 3,699 0.00% Shares
Arax Advisory Partners $278 3 0.00% Shares
Integrated Wealth Concepts LLC $93 1 0.00% Shares

Company insiders 4 insiders · 3 officers · 2 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Robinson Chandler Chief Executive Officer June 30, 2026 M 99,267 0 0 $0
Quan Anh Vu Chief Financial Officer June 30, 2026 M 2,221 0 0 $0
Andrew Cittadine Chief Operating Officer June 30, 2026 M 55,614 0 0 $0
Nicole Sweeny Director June 26, 2026 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Tactic Pharma LLC, Robinson Chandler, Brown Michael J ×4 filings Jan. 30, 2026 4.50% Amendment SEC
Monopar Therapeutics, Hendricks Diane, Leo Karl, Pharma Investments LLC Feb. 7, 2025 13.40% Amendment SEC
GEM PHARMACEUTICALS LLC, DIANE HENDRICKS, KARL LEO, ARTHUR KLAUSNER, PHARMA INVESTMENTS LLC Dec. 23, 2019 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 21 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.52% 3,699 NS April 30, 2026 N-PORT
IWC · iShares Trust 0.12% 15,284 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.08% 18,350 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.03% 31,439 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.02% 3,112 NS May 31, 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 2,949 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.02% 116,348 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 25,913 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 1,184 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.01% 10,218 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.01% 208 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.01% 1,948 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.00% 163 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 1,318 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 162 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 9,937 SH Aug. 8, 2026 Daily
HDG · ProShares Trust 0.00% 4 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 1,833 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 45,173 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 159,786 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 420 SH Aug. 8, 2026 Daily