CAPR Capricor Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$7.21
Price · Aug 18, 2026
Fundamentals as of Aug 14, 2026

CAPR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$7.21
Market Cap
$414M
P/E (TTM)
-3.2
EPS (TTM)
$-2.26
Revenue (TTM)
$0
Div Yield
ROE
-51.1%
Debt/Equity
52W Range
$3 – $40

CAPR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $0
10-point trend, -100.0%
2016-12-31 2025-12-31
EPS $-2.26
9-point trend, -123.8%
2016-12-31 2025-12-31
Free Cash Flow $-73M
9-point trend, -354.7%
2016-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CAPR
Peer Median
P/E (TTM)
5-point trend, -279.2%
-3.2
17.4
P/B
5-point trend, +139.7%
1.4
4.8
Price / FCF
5-point trend, -478.6%
-5.7

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CAPR
Peer Median
ROA
5-point trend, +24.3%
-39.9%
-41.1%
ROE
5-point trend, +13.0%
-51.1%
-52.6%
ROIC
-35.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CAPR
Peer Median
Current Ratio
5-point trend, +2.2%
9.0
7.7
Quick Ratio
5-point trend, -4.8%
8.0

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CAPR
Peer Median
Revenue YoY
5-point trend, -100.0%
-11.6%
Revenue CAGR 3Y
5-point trend, -100.0%
349.7%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CAPR
Peer Median
EPS (Diluted)
5-point trend, -159.8%
$-2.26

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CAPR
Peer Median

CAPR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

HOLD 15 analysts
  • Strong Buy 0 0.0%
  • Buy 0 0.0%
  • Hold 12 80.0%
  • Sell 1 6.7%
  • Strong Sell 2 13.3%

12-Month Price Target

4 analysts · 2026-08-16
Median target $6.00 -16.8%
Mean target $10.50 +45.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.06%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.70 $-0.60 -0.10%
March 31, 2026 $-0.59 $-0.54 -0.05%
Dec. 31, 2025 $-0.62 $-0.55 -0.07%
Sept. 30, 2025 $-0.54 $-0.56 0.02%
June 30, 2025 $-0.57 $-0.48 -0.09%
March 31, 2025 $-0.53 $-0.32 -0.21%
Dec. 31, 2024 $-0.16 $-0.27 0.11%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CAPR $1.66B -12.8 -11.6% -51.1%
PBYI $300M 9.8 -0.91% 13.6% 26.5%
RZLT $388M -4.6 -56.9%
EDIT $201M -1.1 25.4% -395.0% -688.8%
BNTC $307M -11.1 -43.8%
CMPX $958M -45.9%
PROK 1075.0% -7725.2% 6.9%
FENC $263M -22.6 -6.1% -21.8% -69.6%
LXEO $725M -5.3 -51.9%
FHTX $306M -4.6 36.8% -240.3% 80.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -100.0% $0 $22M $25M $3M $244.9K $310.2K $1M $2M $3M $4M $6M $5M
R&D Expense 12-point trend, +984.5% $84M $50M $36M $22M $14M $8M $5M $12M $11M $16M $14M $8M
SG&A Expense 12-point trend, +685.1% $24M $15M $13M $10M $8M $6M $4M $5M $5M $5M $4M $3M
Operating Expenses 12-point trend, +900.9% $108M $65M $49M $32M $21M $14M $9M $17M $16M $21M $18M $11M
Operating Income 12-point trend, -1697.0% $-108M $-43M $-24M $-30M $-21M $-14M $-8M $-15M $-13M $-17M $-13M $-6M
Interest Expense 5-point trend, -100.0% · · · · · · · $0 $398.8K $344.7K $248.6K $200.5K
Other Non-op 12-point trend, +1660.8% $3M $2M $2M $677.9K $915.9K $32.9K $92.1K $136.0K $15M $-2M $-245.5K $-198.6K
Pretax Income 2-point trend, -159.6% $-105M $-40M · · · · · · · · · ·
Income Tax Flat — no change across 2 periods $1.6K $1.6K · · · · · · · · · ·
Net Income 12-point trend, -1589.7% $-105M $-40M $-22M $-29M $-20M $-14M $-8M $-15M $2M $-19M $-13M $-6M
EPS (Basic) 8-point trend, -123.8% $-2.26 $-1.15 $-0.83 $-1.18 $-0.87 $-0.88 · · $0.10 $-1.01 · ·
EPS (Diluted) 9-point trend, -123.8% $-2.26 $-1.15 $-0.83 $-1.18 $-0.87 $-0.88 · $-0.52 $0.09 $-1.01 · ·
Shares (Basic) 10-point trend, +150.5% 46,478,416 35,218,628 26,778,360 24,552,688 23,089,323 15,571,056 3,711,333 2,941,084 23,193,278 18,551,013 · ·
Shares (Diluted) 10-point trend, +150.5% 46,478,416 35,218,628 26,778,360 24,552,688 23,089,323 15,571,056 3,711,333 2,941,084 26,788,076 18,551,013 · ·
EBITDA 11-point trend, -1678.0% $-106M $-41M $-23M $-29M $-21M $-14M $-8M · $-13M $-17M $-13M $-6M
Balance Sheet 22
Annual Balance Sheet data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +3482.5% $288M $11M $15M $10M $35M $33M $4M $4M $6M $3M $6M $8M
Short-term Investments 10-point trend, +140228881.00 · $140M $25M $32M $0 · $6M $3M $8M $13M $8M $0
Prepaid Expense 12-point trend, +1942.6% $5M $2M $995.8K $919.9K $1M $1M $571.4K $724.2K $501.2K $342.9K $210.6K $235.5K
Current Assets 12-point trend, +2682.2% $323M $163M $51M $43M $36M $34M $11M $8M $16M $18M $14M $12M
PP&E (Net) 12-point trend, +7880.8% $18M $6M $6M $5M $2M $850.8K $442.8K $574.2K $372.1K $435.3K $318.6K $229.5K
PP&E (Gross) 12-point trend, +6779.6% $23M $9M $8M $6M $3M $2M $1M $1M $713.7K $686.0K $492.3K $341.0K
Accum. Depreciation 12-point trend, +4515.6% $5M $3M $2M $1M $756.7K $718.6K $579.0K $456.0K $341.6K $250.7K $173.7K $111.6K
Intangibles 8-point trend, -100.0% · · · · $0 $2.2K $6.5K $49.8K $93.0K $142.3K $191.0K $239.8K
Total Assets 12-point trend, +2511.1% $356M $170M $59M $50M $41M $35M $11M $9M $16M $19M $16M $14M
Accounts Payable 12-point trend, -2.6% $2M $3M $6M $5M $3M $3M $898.0K $1M $1M $3M $3M $2M
Accrued Liabilities 2-point trend, +217.0% $16M $5M · · · · · · · · · ·
Short-term Debt 3-point trend, +0.00 · · · · $0 $246.7K $0 · · · · ·
Current Liabilities 12-point trend, +468.9% $36M $21M $31M $24M $4M $3M $898.0K $1M $2M $5M $7M $6M
Capital Leases 6-point trend, +14320389.00 $14M $616.3K $1M $2M $2M $0 · · · · · ·
Total Liabilities 12-point trend, +152.3% $50M $25M $36M $38M $10M $6M $4M $5M $5M $23M $17M $20M
Total Debt 2-point trend, -100.0% · · · · $0 $246.7K · · · · · ·
Common Stock 12-point trend, +390.1% $57.4K $45.6K $31.1K $25.2K $24.2K $20.6K $5.2K $3.1K $26.3K $21.4K $16.3K $11.7K
Retained Earnings 12-point trend, -1266.2% $-305M $-200M $-159M $-137M $-108M $-88M $-74M $-67M $-52M $-54M $-35M $-22M
AOCI 12-point trend, +283154.00 $283.2K $1M $235.8K $105.2K $0 $0 $-757 $12.4K $11.6K $3.5K $9.4K $0
Stockholders' Equity 12-point trend, +4993.7% $306M $145M $23M $12M $31M $28M $7M $5M $11M $-4M $-1M $-6M
Liabilities + Equity 12-point trend, +2511.1% $356M $170M $59M $50M $41M $35M $11M $9M $16M $19M $16M $14M
Shares Outstanding 12-point trend, +390.1% 57,370,909 45,582,288 31,148,320 25,241,402 24,185,001 20,577,123 5,227,398 3,138,748 26,270,491 21,399,019 16,254,985 11,707,051
Cash Flow 16
Annual Cash Flow data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +4408.9% $2M $1M $1M $533.1K $245.7K $143.9K $172.0K $157.7K $144.2K $125.7K $110.9K $41.9K
Stock-based Comp 11-point trend, +1865.1% · $10M $7M $4M $3M $2M $701.0K $2M $2M $2M $2M $496.9K
Amort. of Intangibles 9-point trend, -100.0% · · · $0 $2.2K $4.3K $43.3K $43.3K $49.2K $48.7K $48.7K $10.7K
Other Non-cash 11-point trend, +402.4% $33M $-11M $-12M $29M $1.8K $2M $-52.6K · $-19M $917.0K $356.0K $7M
Operating Cash Flow 12-point trend, -7382.9% $-70M $-40M $-26M $5M $-17M $-10M $-7M $-14M $-14M $-14M $-11M $958.6K
CapEx 12-point trend, +1685.3% $3M $1M $1M $2M $1M $547.6K $0 $316.5K $32.2K $192.0K $129.7K $162.7K
Investing Cash Flow 10-point trend, +1977.8% $97M $-116M $5M $-35M $-1M $5M $-3M $5M $5M $-5M · ·
Debt Issued 5-point trend, -100.0% · · · · · · · $0 $500.0K $5M $0 $5M
Net Debt Issued 4-point trend, -90.4% · · · · · · · · $500.0K $5M $0 $5M
Stock Issued 12-point trend, +237033938.00 $237M $152M $26M $5M $20M $27M $9M $7M $11M $14M $16M $0
Stock Repurchased 3-point trend, +0.00 · · · · · $0 $193 $0 · · · ·
Net Stock Activity 10-point trend, +1341.3% $237M $152M $26M $5M $20M $27M $9M · $11M $14M $16M ·
Financing Cash Flow 10-point trend, +1236.1% $249M $153M $26M $5M $20M $33M $9M $7M $12M $19M · ·
Net Change in Cash 3-point trend, -137.5% · · · · · · · · · $-2M $-2M $6M
Taxes Paid 12-point trend, +1600.00 $1.6K $1.6K $0 $0 $0 $0 $0 $0 $0 $0 $0 $0
Free Cash Flow 11-point trend, -9517.5% $-73M $-41M $-27M $3M $-18M $-11M $-7M · $-14M $-16M $-11M $772.1K
Profitability 6
Annual Profitability data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 10-point trend, -52.0% · -191.1% -95.6% -1163.9% -8549.9% -4412.6% -769.5% · -482.4% -424.6% -228.6% -125.7%
Net Margin 10-point trend, -39.9% · -181.7% -88.5% -1137.4% -8175.9% -4401.9% -760.4% · 91.2% -470.3% -233.0% -129.9%
EBITDA Margin 10-point trend, -48.0% · -184.7% -91.4% -1143.0% -8449.5% -4366.2% -752.4% · -477.0% -421.4% -226.6% -124.8%
ROA 11-point trend, +38.5% -39.9% -35.3% -41.0% -63.5% -52.7% -59.7% -75.1% · 13.9% -108.0% -86.6% -64.9%
ROE 11-point trend, -127.9% -51.1% -37.9% -214.2% -213.3% -58.8% -46.6% -146.8% · 67.3% 747.1% 353.2% 183.3%
ROIC -35.4% · · · · · · · · · · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, +389.1% 9.0 7.8 1.6 1.8 8.8 11.3 11.7 · 9.4 3.7 2.1 1.8
Quick Ratio 11-point trend, +529.8% 8.0 7.2 1.3 1.8 8.4 11.0 11.0 · 8.5 3.3 2.1 1.3
Debt / Equity 2-point trend, -100.0% · · · · 0.0 0.0 · · · · · ·
Interest Coverage 4-point trend, -7.5% · · · · · · · · -32.3 -49.3 -50.7 -30.0
Efficiency 1
Annual Efficiency data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -100.0% 0.0 0.2 0.5 0.1 0.0 0.0 0.1 · 0.2 0.2 0.4 0.5
Per Share 5
Annual Per Share data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +1098.5% $5.33 $3.19 $0.73 $0.47 $1.30 $1.37 $1.31 · $0.43 $-0.19 $-0.06 $-0.53
Revenue / Share 8-point trend, -100.0% $0.00 $0.63 $0.94 $0.10 $0.01 $0.02 $0.27 · $0.10 · · ·
Cash Flow / Share 8-point trend, -182.8% $-1.50 $-1.14 $-0.96 $0.20 $-0.73 $-0.65 $-1.84 · $-0.53 · · ·
Cash / Share 11-point trend, +631.1% $5.02 $0.25 $0.47 $0.38 $1.44 $1.59 $0.75 · $0.23 $0.15 $0.34 $0.69
EPS (TTM) 9-point trend, -123.8% $-2.26 $-1.15 $-0.83 $-1.18 $-0.87 $-0.88 · $-0.52 $0.09 $-1.01 · ·
Growth Rates 2
Annual Growth Rates data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 4-point trend, +45.2% · -11.6% 886.8% 941.9% -21.1% · · · · · · ·
Revenue CAGR 3Y 2-point trend, +5.0% · 349.7% 332.9% · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for CAPR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -100.0% $0 $22M $25M $3M $244.9K $310.2K $1M $2M $3M $4M $6M $5M
Net Income TTM 12-point trend, -1589.7% $-105M $-40M $-22M $-29M $-20M $-14M $-8M $-15M $2M $-19M $-13M $-6M
Market Cap 11-point trend, +277.1% $1.66B $629M $152M $97M $71M $71M $7M · $415M $569M $499M $439M
Enterprise Value 2-point trend, -5.7% · · · · $36M $38M · · · · · ·
P/E 9-point trend, +51.5% -12.8 -12.0 -5.9 -3.3 -3.4 -3.9 · -7.9 175.6 -26.3 · ·
P/S 10-point trend, -69.2% · 28.2 6.0 38.2 289.4 227.5 6.7 · 155.7 142.4 90.4 91.7
P/B 11-point trend, +107.7% 5.4 4.3 6.7 8.3 2.3 2.5 1.0 · 37.0 -142.2 -483.7 -70.3
P / Tangible Book 6-point trend, +116.3% 5.4 4.3 6.7 8.3 2.3 2.5 · · · · · ·
P / Cash Flow 11-point trend, -105.2% -23.7 -15.7 -6.0 19.8 -4.2 -7.0 -1.0 · -29.2 -36.0 -46.1 458.0
P / FCF 11-point trend, -104.0% -22.8 -15.3 -5.7 33.4 -3.9 -6.7 -1.0 · -29.1 -35.6 -45.6 568.6
EV / EBITDA 2-point trend, +38.3% · · · · -1.7 -2.8 · · · · · ·
EV / FCF 2-point trend, +44.5% · · · · -2.0 -3.6 · · · · · ·
EV / Revenue 2-point trend, +19.4% · · · · 146.9 123.0 · · · · · ·
Earnings Yield 9-point trend, -106.1% -7.8% -8.3% -17.0% -30.6% -29.7% -25.7% · -12.7% 0.57% -3.8% · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0$22M$25M$3M$244.9K
Operating Margin % -191.1%-95.6%-1163.9%-8549.9%
Net Income $-105M$-40M$-22M$-29M$-20M
Diluted EPS $-2.26$-1.15$-0.83$-1.18$-0.87
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.0
Current Ratio 9.07.81.61.88.8
Quick Ratio 8.07.21.31.88.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-73M$-41M$-27M$3M$-18M

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Institutional owners (13F) 208 filers · $984.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
41 (-29 vs prior Q) 31 (+10 vs prior Q) 71 (+10 vs prior Q) 52 (+10 vs prior Q) +8.5M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
TANG CAPITAL MANAGEMENT LLC $98,725,592 4,099,900 10.03% Shares
MONTANOVA CAPITAL, LLC $98,554,239 4,092,784 10.01% Shares
STATE STREET CORP $81,803,372 3,397,150 8.31% Shares
VANGUARD GROUP INC $64,543,514 2,236,435 6.56% Shares
VANGUARD CAPITAL MANAGEMENT LLC $55,327,990 2,297,674 5.62% Shares
GOLDMAN SACHS GROUP INC $36,815,454 1,528,881 3.74% Shares
RA CAPITAL MANAGEMENT, L.P. $36,308,884 1,507,844 3.69% Shares
Boxer Capital Management, LLC $33,595,356 1,395,156 3.41% Shares
GEODE CAPITAL MANAGEMENT, LLC $28,392,757 1,178,893 2.88% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $25,637,976 1,064,700 2.60% Call option
PERCEPTIVE ADVISORS LLC $24,080,000 1,000,000 2.45% Call option
FMR LLC $22,104,019 917,941 2.25% Shares
Soleus Capital Management, L.P. $18,342,627 761,737 1.86% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $15,316,975 636,087 1.56% Shares
DG Capital Management, LLC $14,727,208 611,595 1.50% Shares
Ikarian Capital, LLC $14,549,497 604,215 1.48% Shares
CITADEL ADVISORS LLC $14,078,589 584,659 1.43% Shares
DIADEMA PARTNERS LP $12,868,352 534,400 1.31% Put option
SUSQUEHANNA INTERNATIONAL GROUP, LLP $12,714,240 528,000 1.29% Put option
PERCEPTIVE ADVISORS LLC $12,040,000 500,000 1.22% Put option
Balyasny Asset Management L.P. $11,723,011 486,836 1.19% Shares
SB Capital Management Inc $11,544,028 400,001 1.17% Shares
CITADEL ADVISORS LLC $11,394,656 473,200 1.16% Call option
Caption Management, LLC $10,802,288 448,600 1.10% Call option
J. Goldman & Co LP $10,289,890 427,321 1.05% Shares
Jones Hill Capital LP $10,131,684 420,751 1.03% Shares
MERCER GLOBAL ADVISORS INC /ADV $9,697,762 402,731 0.99% Shares
VANGUARD FIDUCIARY TRUST CO $8,970,739 372,539 0.91% Shares
Ikarian Capital, LLC $8,428,000 350,000 0.86% Call option
DIADEMA PARTNERS LP $7,929,544 329,300 0.81% Call option
D. E. Shaw & Co., Inc. $7,585,200 315,000 0.77% Call option
GROUP ONE TRADING LLC $6,564,425 272,609 0.67% Shares
CITADEL ADVISORS LLC $6,222,272 258,400 0.63% Put option
RTW INVESTMENTS, LP $6,020,000 250,000 0.61% Shares
MILLENNIUM MANAGEMENT LLC $5,632,938 233,926 0.57% Shares
Palo Alto Investors LP $5,532,693 229,763 0.56% Shares
BANK OF AMERICA CORP /DE/ $5,132,387 213,139 0.52% Shares
Trexquant Investment LP $4,762,855 197,793 0.48% Shares
Caption Management, LLC $4,659,480 193,500 0.47% Put option
BOOTHBAY FUND MANAGEMENT, LLC $4,646,525 192,962 0.47% Shares
RAYMOND JAMES FINANCIAL INC $4,490,920 186,500 0.46% Shares
Moody Aldrich Partners LLC $4,280,316 177,754 0.43% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $3,875,387 160,938 0.39% Shares
Woodline Partners LP $3,341,654 138,773 0.34% Shares
MILLENNIUM MANAGEMENT LLC $3,010,000 125,000 0.31% Call option
PFM Health Sciences, LP $2,943,082 122,221 0.30% Shares
LMR Partners LLP $2,819,768 117,100 0.29% Call option
Pier Capital, LLC $2,694,745 111,908 0.27% Shares
BOOTHBAY FUND MANAGEMENT, LLC $2,550,072 105,900 0.26% Call option
Jefferies Financial Group Inc. $2,546,580 105,755 0.26% Shares
JANE STREET GROUP, LLC $2,330,944 96,800 0.24% Call option
Point72 Asset Management, L.P. $2,280,930 94,723 0.23% Shares
Swiss National Bank $2,237,032 92,900 0.23% Shares
ADAR1 Capital Management, LLC $2,181,479 90,593 0.22% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,967,366 64,716 0.20% Shares
MARSHALL WACE, LLP $1,906,895 79,190 0.19% Shares
Black Diamond Financial, LLC $1,904,174 79,077 0.19% Shares
CITIGROUP INC $1,868,656 77,602 0.19% Shares
OPPENHEIMER & CO INC $1,823,193 75,714 0.19% Shares
Rock Springs Capital Management LP $1,792,708 74,448 0.18% Shares
Longaeva Partners L.P. $1,783,028 74,046 0.18% Shares
ALLIANCEBERNSTEIN L.P. $1,741,920 57,300 0.18% Shares
Caption Management, LLC $1,733,760 72,000 0.18% Shares
RHUMBLINE ADVISERS $1,634,564 67,881 0.17% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,610,663 66,888 0.16% Shares
Rafferty Asset Management, LLC $1,453,782 60,373 0.15% Shares
Foundations Investment Advisors, LLC $1,445,041 60,010 0.15% Shares
BARCLAYS PLC $1,401,143 58,187 0.14% Shares
BlackRock, Inc. $1,334,104 55,403 0.14% Shares
Bank of New York Mellon Corp $1,314,142 54,574 0.13% Shares
Quinn Opportunity Partners LLC $1,076,328 44,698 0.11% Shares
JANE STREET GROUP, LLC $1,052,296 43,700 0.11% Put option
MILLENNIUM MANAGEMENT LLC $1,042,664 43,300 0.11% Put option
FRANKLIN RESOURCES INC $1,024,941 42,564 0.10% Shares
GLENMEDE TRUST CO NA $961,634 39,935 0.10% Shares
D. E. Shaw & Co., Inc. $884,892 36,748 0.09% Shares
HBK Sorce Advisory LLC $876,689 223,076 0.09% Shares
AlphaQuest LLC $867,416 30,056 0.09% Shares
J. Goldman & Co LP $866,880 36,000 0.09% Call option
WOLVERINE TRADING, LLC $786,942 106,200 0.08% Put option
VANGUARD ASSET MANAGEMENT, Ltd $776,941 32,265 0.08% Shares
WELLINGTON MANAGEMENT GROUP LLP $759,917 31,558 0.08% Shares
CITIGROUP INC $758,520 31,500 0.08% Call option
MetLife Investment Management, LLC $755,630 31,380 0.08% Shares
ALGERT GLOBAL LLC $737,089 30,610 0.07% Shares
PROFUND ADVISORS LLC $734,007 30,482 0.07% Shares
HAP Trading, LLC $731,500 191,200 0.07% Call option
ENVESTNET ASSET MANAGEMENT INC $699,717 29,058 0.07% Shares
Persistent Asset Partners Ltd $697,076 831 0.07% Call option
Vanguard Global Advisers, LLC $687,532 28,552 0.07% Shares
JANUS HENDERSON GROUP PLC $686,588 22,600 0.07% Shares
TWINBEECH CAPITAL LP $682,355 28,337 0.07% Shares
LPL Financial LLC $659,238 27,377 0.07% Shares
WOLVERINE TRADING, LLC $655,785 88,500 0.07% Call option
COMMONWEALTH EQUITY SERVICES, LLC $644,740 26,775 0.07% Shares
Aquatic Capital Management LLC $632,269 26,257 0.06% Shares
PEAK6 LLC $602,000 25,000 0.06% Call option
SEVEN GRAND MANAGERS, LLC $602,000 25,000 0.06% Shares
Anson Funds Management LP $602,000 25,000 0.06% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $596,365 24,766 0.06% Shares

Company insiders 29 insiders · 12 officers · 15 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Linda Marban CHIEF EXECUTIVE OFFICER Jan. 4, 2021 A 46,715 0 0 $0
Peter M Strumph Chief Executive Officer Dec. 11, 2008 P 4,580 0 0 $0
Anthony Bergmann CHIEF FINANCIAL OFFICER June 25, 2026 M 11,223 0 3 $-759,158
Leland Gershell CHIEF FINANCIAL OFFICER March 16, 2016 P 2,100 0 0 $0
Daron Evans Chief Financial Officer March 30, 2012 P 25,652 0 0 $0
Karen Krasney EVP, GENERAL COUNSEL June 25, 2026 M 30,547 0 3 $-759,158
Michael T Maurer CHIEF COMMERCIAL OFFICER May 26, 2026 A 0 0 $0
Deborah Ascheim Chief Medical Officer July 24, 2018 A 0 0 $0
Rachel Smith Vice President of R&D Dec. 22, 2017 M 18,504 0 0 $0
Andrew Warwick Hamer VP of Medical Affairs March 3, 2015 A 0 0 $0
Hsiao Lieu Executive VP, Clinical Dev. March 30, 2012 P 12,600 0 0 $0
Richard B Brewer Executive Chairman March 30, 2012 P 125,000 0 0 $0
George W Dunbar JR Director Jan. 5, 2026 A 14,306 0 0 $0
Karimah Es Sabar Director July 23, 2021 A 0 0 $0
Louis Manzo Director Jan. 4, 2021 A 44,603 0 0 $0
Earl M Collier JR Director Jan. 4, 2021 A 0 0 $0
Joshua A Kazam Director Jan. 2, 2018 A 38,084 0 0 $0
Louis J Grasmick Director March 16, 2016 P 1,059,740 0 0 $0
Gregory W Schafer Director March 3, 2015 A 0 0 $0
Peter M Kash Director July 18, 2011 J 1,596,208 0 0 $0
Mieyal Paul A Director May 10, 2011 A 0 0 $0
Arie Belldegrun Director May 10, 2011 A 0 0 $0
Pedro P Granadillo Director May 10, 2011 A 0 0 $0
David M Tanen Director July 21, 2009 A 1,511,705 0 0 $0
Nippon Shinyaku Co Ltd 10% owner Sept. 20, 2024 P 7,090,351 0 0 $0
CEDARS SINAI MEDICAL CENTER 10% owner May 9, 2017 P 4,049,959 0 0 $0
Eduardo Marban 10% owner Aug. 19, 2015 P 268,557 0 0 $0
Frank Litvack May 13, 2026 M 133,776 0 0 $0
David B Musket Jan. 5, 2026 A 22,891 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 12 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
NANCELOU, INC., LOUIS GRASMICK, NANCY GRASMICK, GRANT GRASMICK ×4 filings March 21, 2016 Initial filing SEC
CONISTON CORPORATION, LOUIS MANZO ×4 filings March 21, 2016 Initial filing SEC
Linda Marbán, Ph.D. ×2 filings March 21, 2016 Initial filing SEC
Frank Litvack ×2 filings March 13, 2015 Initial filing SEC
MD BTI, LLC, Edward St. John, LLC, Edward A. St. John March 19, 2014 Initial filing SEC
Iota Investors LLC, Wexford Spectrum Investors LLC, Wexford Capital LP, Wexford GP LLC, Charles E. Davidson, Joseph M. Jacobs ×3 filings Dec. 5, 2013 Initial filing SEC
Eduardo Marbán, M.D., Ph.D. Dec. 3, 2013 Initial filing SEC
Joshua A. Kazam Sept. 25, 2007 Initial filing SEC
David M. Tanen Sept. 25, 2007 Initial filing SEC
Peter M. Kash Sept. 25, 2007 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Sept. 24, 2007 Initial filing Board campaign SEC
Undisclosed reporting person Aug. 22, 2006 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 24 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.95% 10,606 NS April 30, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.43% 67,108 NS April 30, 2026 N-PORT
IBRN · iShares Trust 0.22% 4,102 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.10% 85,131 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.08% 57,651 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.04% 18,911 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.04% 309,586 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.03% 2,051 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.03% 10,262 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.03% 22,465 NS April 30, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.02% 139,201 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.02% 1,604 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.01% 484,355 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.01% 1,622 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 591,352 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 1,372,168 SH Aug. 8, 2026 Daily
HDG · ProShares Trust 0.01% 41 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 1,350 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.00% 15,068 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.00% 2,986 SH Aug. 8, 2026 Daily
ITOT · iShares Trust 0.00% 67,137 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 13,054 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,655,365 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 4,427 SH Aug. 8, 2026 Daily