ALT Altimmune, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$3.02
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026
52W Range
$3–$6
12% of range
Analyst Rating
BUY
15 analysts
Price Target
$17
+471% upside
P/E (TTM)
-3.0
ROE
-45.6%
Net Profit Margin
-214861.0%

ALT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$3.02
Market Cap
$334M
P/E (TTM)
-3.0
EPS (TTM)
$-1.00
Revenue (TTM)
$41.0K
Div Yield
—
ROE
-45.6%
Debt/Equity
0.2
52W Range
$3 – $6

ALT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $41.0K
10-point trend, -98.7%
2016-12-31 → 2025-12-31
EPS $-1.00
7-point trend, -133.9%
2016-12-31 → 2025-12-31
Free Cash Flow $-68M
8-point trend, -133.5%
2016-12-31 → 2025-12-31
Margins -214861.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ALT
Peer Median
P/E (TTM)
5-point trend, +7.4%
-3.0
19.6
P/S (TTM)
5-point trend, +11366.0%
8153.9
24.9
P/B
5-point trend, -5.6%
1.5
3.1
EV / EBITDA
5-point trend, -668.7%
-1.0
—
Price / FCF
5-point trend, +51.0%
-4.9
—

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ALT
Peer Median
Operating Margin
5-point trend, -10387.8%
-230461.0%
—
Net Profit Margin
5-point trend, -9660.1%
-214861.0%
-298.0%
ROA
5-point trend, -0.4%
-42.0%
-56.6%
ROE
5-point trend, +4.1%
-45.6%
-70.8%
ROIC
5-point trend, +52.7%
-36.2%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ALT
Peer Median
Debt / Equity
5-point trend, +272.0%
0.2
—
Current Ratio
5-point trend, +66.1%
18.5
5.2
Quick Ratio
5-point trend, +75.1%
18.2
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ALT
Peer Median
Revenue YoY
5-point trend, -99.1%
105.0%
—
Revenue CAGR 3Y
5-point trend, -99.1%
-83.5%
—
Revenue CAGR 5Y
5-point trend, -99.1%
-65.3%
—

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ALT
Peer Median
EPS (Diluted)
5-point trend, +57.4%
$-1.00
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ALT
Peer Median

ALT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 15 analysts
  • Strong Buy 4 26.7%
  • Buy 9 60.0%
  • Hold 2 13.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

9 analysts · 2026-08-19
Median target $18.00 +497.0%
Mean target $17.22 +471.2%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.05%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.12 $-0.14 0.02%
March 31, 2026 $-0.18 $-0.25 0.07%
Dec. 31, 2025 $-0.27 $-0.25 -0.02%
Sept. 30, 2025 $-0.21 $-0.28 0.07%
June 30, 2025 $-0.27 $-0.33 0.06%
March 31, 2025 $-0.26 $-0.37 0.11%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ALT $400M -3.6 105.0% -214861.0% -45.6% —
CBIO $327M -24.2 -86.7% -1419.6% -90.0% —
ASMB $539M -61.8 153.5% -8.5% -5.5% —
NVCT $194M -5.7 — — -149.9% —
MDXG $1.00B 21.2 20.0% 11.6% 20.5% 82.6%
SPRY $1.16B -6.7 -5.5% -203.3% -111.8% —
PRME $626M -2.6 55.3% -4342.4% -221.4% —
ARTV — -1.3 -99.2% — — —
EIKN — — — — — —
OVID $212M -4.0 1181.3% -240.1% -18.7% —
PRLD — -2.2 73.4% -819.6% -137.7% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 10-point trend, -98.7% $41.0K $20.0K $426.0K $-68.0K $4M $8M $6M $10M $11M $3M · ·
R&D Expense 12-point trend, +612.8% $66M $82M $66M $71M $75M $50M $18M $18M $18M $7M $5M $9M
SG&A Expense 12-point trend, +157.5% $28M $21M $18M $17M $15M $13M $9M $10M $8M $7M $6M $11M
Operating Expenses 12-point trend, +363.8% $95M $103M $96M $88M $101M $63M $27M $53M $63M $14M $14M $20M
Operating Income 12-point trend, -827.2% $-94M $-103M $-96M $-88M $-97M $-55M $-21M $-43M $-52M $-11M $-3M $-10M
Interest Expense 10-point trend, -83.4% · · $35.0K $8.0K $5.0K $9.4K $2.2K $297.1K $162.1K $38.5K $54.6K $210.4K
Interest Income 10-point trend, +720148.3% $8M $8M $7M $3M $203.0K $322.5K $843.4K $226.6K $47.6K $1.0K · ·
Other Non-op 12-point trend, -24834.4% $-190.0K $48.0K $166.0K $-32.0K $-374.0K $24.1K $15.1K $277.9K $5.7K $42.3K $8.1K $-762
Pretax Income 12-point trend, -797.3% $-89M $-95M $-88M $-85M $-97M $-54M $-21M $-45M $-52M $-11M $-3M $-10M
Income Tax 9-point trend, -1202.9% $-681.0K · · $-197.0K · $-5M $-58.5K $-6M $-6M $0 $61.7K $61.7K
Net Income 12-point trend, -784.9% $-88M $-95M $-88M $-85M $-97M $-49M $-21M $-39M $-46M $-11M $-3M $-10M
EPS (Basic) 9-point trend, -488.2% $-1.00 $-1.34 $-1.66 $-1.81 $-2.35 $-1.91 · · · $2.97 $-0.05 $-0.17
EPS (Diluted) 9-point trend, -488.2% $-1.00 $-1.34 $-1.66 $-1.81 $-2.35 $-1.91 · · · $2.95 $-0.05 $-0.17
Shares (Basic) 9-point trend, +53.1% 88,104,132 71,003,399 53,246,937 46,926,349 41,283,498 25,637,023 · · · 65,306,962 63,986,013 57,535,325
Shares (Diluted) 9-point trend, +53.1% 88,104,132 71,003,399 53,246,937 46,926,349 41,283,498 25,637,023 · · · 65,657,802 63,986,013 57,535,325
EBITDA 11-point trend, -827.2% $-94M $-103M $-96M $-88M $-96M $-55M $-21M $-43M · $-11M $-3M $-10M
Balance Sheet 29
Annual Balance Sheet data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +134.7% $44M $37M $135M $111M $190M $116M $9M $34M $9M $3M $16M $19M
Short-term Investments 8-point trend, +229696000.00 $230M $95M $63M $74M · $100M $28M · · $67M $0 ·
Receivables · · · · · · · · · · · $400.0K
Prepaid Expense 12-point trend, +1384.5% $3M $2M $7M $5M $8M $2M $470.2K $548.1K $994.3K $420.4K $181.7K $199.2K
Current Assets 12-point trend, +1345.1% $278M $137M $210M $193M $204M $230M $39M $39M $23M $4M $17M $19M
PP&E (Net) 12-point trend, -4.2% $312.0K $413.0K $651.0K $1M $1M $1M $1M $1M $603.1K $177.9K $233.7K $325.8K
PP&E (Gross) 12-point trend, +4.9% $3M $3M $3M $3M $3M $3M $2M $2M $2M $1M $2M $3M
Accum. Depreciation 12-point trend, +6.2% $2M $2M $2M $1M $2M $2M $1M $1M $951.8K $905.3K $2M $2M
Goodwill 5-point trend, -100.0% · · · · · · $0 $0 · $19M $22M $2M
Intangibles 9-point trend, -100.0% · $0 $0 $12M $12M $13M $13M $14M $39M $15M · ·
Other Non-current Assets 12-point trend, +2569.3% $1M $2M $363.0K $615.0K $872.0K $977.2K $128.5K $183.7K $238.9K $22.2K $53.4K $53.4K
Total Assets 12-point trend, +1173.7% $280M $139M $211M $207M $219M $245M $54M $55M $63M $38M $20M $22M
Accounts Payable 12-point trend, +594.2% $3M $211.0K $2M $5M $2M $612.3K $18.2K $372.9K $129.1K $2M $521.1K $391.4K
Accrued Liabilities 5-point trend, +283.8% · · · · · $11M $4M $4M $4M $3M · ·
Short-term Debt 3-point trend, -84.4% · · · · · · · $71.6K $49.7K $458.6K · ·
Current Liabilities 12-point trend, +480.9% $15M $10M $12M $17M $18M $12M $4M $5M $4M $5M $2M $3M
Capital Leases 7-point trend, -22.9% $1M $1M $175.0K $672.0K $1M $1M $1M · · · · ·
Deferred Tax 5-point trend, -81.7% · · · · · · · $58.5K $6M $442.6K $380.8K $319.0K
Other Non-current Liabilities 12-point trend, +1066.6% $6M $5M $40.0K $60.0K $80.0K $110.3K $130.2K $140.1K $160.0K $442.6K $433.4K $493.1K
Total Liabilities 12-point trend, +1385.8% $55M $16M $17M $22M $20M $19M $9M $6M $14M $6M $3M $4M
Long-term Debt 4-point trend, +6419.1% $34M · · · · · · $500.0K $500.0K $526.0K · ·
Total Debt 8-point trend, +4495.2% $34M · · $5M $1M $2M $2M $71.6K · · $0 $746.1K
Common Stock 12-point trend, +73.0% $11.0K $7.0K $7.0K $5.0K $4.0K $3.7K $1.5K $876 $61 $692 $6.4K $6.4K
Paid-in Capital 12-point trend, +268.2% $879M $690M $665M $568M $497M $417M $188M $170M $122M $71M $240M $239M
Retained Earnings 12-point trend, -194.8% $-649M $-561M $-466M $-378M $-293M $-186M $-137M $-117M $-78M $-31M $-224M $-220M
AOCI 12-point trend, -2047.0% $-5M $-5M $-5M $-5M $-5M $-5M $-5M $-5M $-5M $-8M $0 $-229.5K
Stockholders' Equity 12-point trend, +1130.7% $225M $124M $194M $185M $199M $226M $46M $48M $39M $32M $43M $18M
Liabilities + Equity 12-point trend, +1173.7% $280M $139M $211M $207M $219M $245M $54M $55M $63M $38M $20M $22M
Shares Outstanding 12-point trend, +74.3% 110,882,735 72,352,701 70,677,400 49,199,845 40,993,768 37,142,946 15,312,167 9,078,238 608,499 6,917,204 64,382,086 63,603,303
Cash Flow 16
Annual Cash Flow data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
D&A 4-point trend, -152.9% · · · $-205.0K $551.0K $428.9K $387.3K · · · · ·
Stock-based Comp 12-point trend, +871.0% $16M $14M $11M $8M $6M $3M $1M $773.2K $1M $965.4K $613.0K $2M
Deferred Tax 7-point trend, -1202.9% $-681.0K · · · · · $-58.5K $-6M $-3M $61.8K $61.7K $61.7K
Restructuring 3-point trend, +0.00 · · · · · · · · · $0 $3M $0
Other Non-cash 3-point trend, +21.3% · · · $14M $13M $12M · · · · · ·
Operating Cash Flow 12-point trend, -697.0% $-68M $-80M $-76M $-63M $-78M $-34M $-10M $-9M $-20M $-6M $-3M $-8M
CapEx 11-point trend, -88.1% $11.0K · $47.0K $126.0K $12M $204.0K $1.2K $975.4K $112.4K $125.0K $86.5K $92.3K
Investing Cash Flow 9-point trend, -1065.1% $-132M $-28M $14M $-73M $88M $-72M $-28M $-1M $14M · · ·
Debt Issued $35M · · · · · · · · · · ·
Net Debt Issued $35M · · · · · · · · · · ·
Stock Issued 10-point trend, +857.6% $174M $10M $87M $56M $65M $48M · $4M · $4M $973.1K $18M
Net Stock Activity 10-point trend, +857.6% $174M $10M $87M $56M $65M $48M · $4M · $4M $973.1K $18M
Financing Cash Flow 9-point trend, +1205.7% $207M $10M $86M $57M $65M $213M $13M $32M $16M · · ·
Net Change in Cash 12-point trend, -16.3% $7M $-98M $24M $-79M $74M $107M $-25M $22M $9M $138M $-3M $8M
Free Cash Flow 10-point trend, -688.5% $-68M · $-76M $-63M $-90M $-35M $-10M $-10M · $201M $-3M $-9M
Levered FCF 6-point trend, -614.5% · · · $-63M · $-35M $-10M $-11M · · $-3M $-9M
Profitability 7
Annual Profitability data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 9-point trend, -3340.2% -230461.0% -515860.0% -22518.5% 129029.4% -2197.4% -669.5% -370.0% -414.6% · -6699.0% · ·
Net Margin 9-point trend, -286.4% -214861.0% -475295.0% -20762.2% 124577.9% -2201.4% -599.2% -353.7% -379.2% · 115286.4% · ·
Pretax Margin 9-point trend, -277.6% -216522.0% -475295.0% -20762.2% 124867.7% -2201.4% -665.4% -354.7% -438.7% · 121929.0% · ·
EBITDA Margin 9-point trend, -3340.2% -230461.0% -515860.0% -22518.5% 129330.9% -2184.9% -665.9% -370.0% -414.6% · -6699.0% · ·
ROA 11-point trend, +17.4% -42.0% -54.3% -42.4% -39.8% -41.9% -32.8% -37.7% -66.5% · 158.5% -16.4% -50.9%
ROE 11-point trend, +41.3% -45.6% -74.0% -51.3% -43.4% -47.5% -23.1% -43.2% -89.0% · 619.4% -19.7% -77.8%
ROIC 8-point trend, +32.9% -36.2% · · -46.1% · -21.7% -45.2% -76.5% · -54.7% -20.8% -53.9%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, +148.8% 18.5 13.1 17.3 11.3 11.2 19.2 10.0 8.7 · 1.1 7.9 7.5
Quick Ratio 11-point trend, +147.2% 18.2 12.6 16.3 10.8 10.4 18.0 9.5 7.4 · 1.1 7.1 7.4
Debt / Equity 8-point trend, +273.8% 0.2 · · 0.0 0.0 0.0 0.0 0.0 · · 0.0 0.0
LT Debt / Equity 5-point trend, +272.0% 0.2 · · 0.0 0.0 0.0 0.0 · · · · ·
Interest Coverage 8-point trend, -5558.4% · · -2740.8 -10967.5 -17134.7 -5816.7 -9565.5 -144.2 · · -62.3 -48.4
Efficiency 1
Annual Efficiency data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 9-point trend, -85.7% 0.0 0.0 0.0 -0.0 0.0 0.1 0.1 0.2 · 0.0 · ·
Per Share 5
Annual Per Share data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +606.0% $2.03 $1.71 $2.75 $3.77 $4.86 $6.08 $2.97 $5.32 · $0.29 $0.26 $0.29
Revenue / Share 6-point trend, -80.8% $0.00 $0.00 $0.01 $-0.00 $0.11 · · · · $0.00 · ·
Cash Flow / Share 6-point trend, -125.0% $-0.77 $-1.12 $-1.42 $-1.33 $-1.90 · · · · $3.07 · ·
Cash / Share 11-point trend, +34.7% $0.39 $0.51 $1.91 $2.26 $4.64 $3.12 $0.59 $3.71 · $2.27 $0.24 $0.29
EPS (TTM) 12-point trend, -488.2% $-1.00 $-1.34 $-1.66 $-1.81 $-2.35 $-1.91 $2.92 $2.92 $2.92 $2.95 $-0.05 $-0.17
Growth Rates 3
Annual Growth Rates data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 3-point trend, +327.7% 105.0% -95.3% · · -46.1% · · · · · · ·
Revenue CAGR 3Y 2-point trend, -33.2% · -83.5% -62.7% · · · · · · · · ·
Revenue CAGR 5Y -65.3% · · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for ALT
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 10-point trend, -98.7% $41.0K $20.0K $426.0K $-68.0K $4M $8M $6M $10M $11M $3M · ·
Net Income TTM 12-point trend, -784.9% $-88M $-95M $-88M $-85M $-97M $-49M $-21M $-39M $-46M $-11M $-3M $-10M
Market Cap 8-point trend, +2040.4% $400M $522M $795M $809M $376M $419M $29M $19M · · · ·
Enterprise Value 6-point trend, +1178.0% $161M · · $629M $187M $205M $-6M $-15M · · · ·
P/E 9-point trend, -117.7% -3.6 -5.4 -6.8 -9.1 -3.9 -5.9 0.6 0.7 20.4 · · ·
P/S 8-point trend, +539237.6% 9763.1 26083.1 1866.5 -11902.0 85.1 51.2 5.0 1.8 · · · ·
P/B 8-point trend, +359.8% 1.8 4.2 4.1 4.4 1.9 1.9 0.6 0.4 · · · ·
P / Tangible Book 6-point trend, -9.5% 1.8 4.2 4.1 4.7 2.0 2.0 · · · · · ·
P / Cash Flow 8-point trend, -197.6% -5.9 -6.5 -10.5 -12.9 -4.8 -12.2 -3.0 -2.0 · · · ·
P / FCF 7-point trend, -228.4% -5.9 · -10.5 -12.9 -4.2 -12.1 -3.0 -1.8 · · · ·
EV / EBITDA 6-point trend, -588.7% -1.7 · · -7.2 -1.9 -3.8 0.3 0.3 · · · ·
EV / FCF 6-point trend, -265.4% -2.4 · · -10.0 -2.1 -5.9 0.7 1.4 · · · ·
EV / Revenue 6-point trend, +271731.9% 3929.7 · · -9250.6 42.3 25.0 -1.1 -1.4 · · · ·
Earnings Yield 9-point trend, -666.5% -27.7% -18.6% -14.8% -11.0% -25.7% -16.9% 154.5% 141.8% 4.9% · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $41.0K$20.0K$426.0K$-68.0K$4M
Operating Margin % -230461.0%-515860.0%-22518.5%129029.4%-2197.4%
Net Income $-88M$-95M$-88M$-85M$-97M
Diluted EPS $-1.00$-1.34$-1.66$-1.81$-2.35
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.2——0.00.0
Current Ratio 18.513.117.311.311.2
Quick Ratio 18.212.616.310.810.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-68M—$-76M$-63M$-90M

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Institutional owners (13F) 238 filers · $355.5M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
65 (+39 vs prior Q) 16 (-17 vs prior Q) 78 (-4 vs prior Q) 38 (-1 vs prior Q) +79.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Deep Track Capital, LP $58,520,000 19,250,000 16.46% Shares
STATE STREET CORP $36,779,562 12,098,540 10.35% Shares
TCG Crossover Management, LLC $30,400,000 10,000,000 8.55% Shares
VANGUARD CAPITAL MANAGEMENT LLC $24,860,366 8,177,752 6.99% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $22,284,006 7,330,265 6.27% Shares
VIKING GLOBAL INVESTORS LP $20,368,000 6,700,000 5.73% Shares
RA CAPITAL MANAGEMENT, L.P. $19,760,000 6,500,000 5.56% Shares
GEODE CAPITAL MANAGEMENT, LLC $13,042,903 4,289,189 3.67% Shares
Woodline Partners LP $10,336,948 3,400,312 2.91% Shares
MILLENNIUM MANAGEMENT LLC $10,059,731 3,309,122 2.83% Shares
Trails Edge Capital Partners, LP $8,086,400 2,660,000 2.27% Shares
TWO SIGMA INVESTMENTS, LP $7,238,672 2,381,142 2.04% Shares
GOLDMAN SACHS GROUP INC $5,713,595 1,879,472 1.61% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5,469,872 1,799,300 1.54% Call option
GREAT POINT PARTNERS LLC $5,293,345 1,741,232 1.49% Shares
Weiss Asset Management LP $4,653,641 1,530,803 1.31% Shares
Nantahala Capital Management, LLC $4,560,000 1,500,000 1.28% Shares
VANGUARD FIDUCIARY TRUST CO $3,930,723 1,293,001 1.11% Shares
Cormorant Asset Management, LP $3,800,000 1,250,000 1.07% Shares
TWO SIGMA ADVISERS, LP $2,865,979 793,900 0.81% Shares
VANGUARD GROUP INC $2,531,996 701,384 0.71% Shares
MARSHALL WACE, LLP $2,424,799 797,631 0.68% Shares
Ghisallo Capital Management LLC $2,280,000 750,000 0.64% Shares
FMR LLC $2,276,297 748,782 0.64% Shares
BlackRock, Inc. $2,190,606 720,594 0.62% Shares
TANG CAPITAL MANAGEMENT LLC $2,024,707 666,022 0.57% Shares
CITADEL ADVISORS LLC $1,918,240 631,000 0.54% Call option
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,898,477 624,499 0.53% Shares
DIMENSIONAL FUND ADVISORS LP $1,789,581 588,678 0.50% Shares
BANK OF AMERICA CORP /DE/ $1,711,815 563,097 0.48% Shares
Point72 Asset Management, L.P. $1,480,127 486,884 0.42% Shares
Rock Springs Capital Management LP $1,433,254 471,465 0.40% Shares
Beirne Wealth Consulting Services, LLC $1,282,449 421,858 0.36% Shares
BNP PARIBAS FINANCIAL MARKETS $1,128,375 371,176 0.32% Shares
BARCLAYS PLC $1,021,313 335,958 0.29% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $990,128 325,700 0.28% Put option
RHUMBLINE ADVISERS $941,193 309,606 0.26% Shares
LMR Partners LLP $912,000 300,000 0.26% Shares
CITIGROUP INC $857,496 282,071 0.24% Shares
Steward Partners Investment Advisory, LLC $810,680 266,671 0.23% Shares
MANGROVE PARTNERS IM, LLC $727,411 239,280 0.20% Shares
Baird Financial Group, Inc. $722,067 237,522 0.20% Shares
BROWN WEALTH MANAGEMENT, LLC $717,853 236,136 0.20% Shares
JANE STREET GROUP, LLC $691,296 227,400 0.19% Call option
Rafferty Asset Management, LLC $684,182 225,060 0.19% Shares
COMMONWEALTH EQUITY SERVICES, LLC $652,300 214,574 0.18% Shares
WOLVERINE TRADING, LLC $637,478 168,200 0.18% Call option
Squarepoint Ops LLC $615,235 202,380 0.17% Shares
ALPS ADVISORS INC $600,017 197,374 0.17% Shares
STIFEL FINANCIAL CORP $584,799 192,368 0.16% Shares
Jump Financial, LLC $577,600 190,000 0.16% Shares
Man Group plc $528,571 173,872 0.15% Shares
WELLS FARGO & COMPANY/MN $506,063 166,468 0.14% Shares
Knoll Capital Management, LLC $486,400 160,000 0.14% Shares
Birchview Capital, LP $464,150 152,681 0.13% Shares
ALLIANCEBERNSTEIN L.P. $433,818 140,850 0.12% Shares
WELLINGTON MANAGEMENT GROUP LLP $407,053 133,899 0.11% Shares
Brevan Howard Capital Management LP $397,574 130,781 0.11% Shares
XTX Topco Ltd $389,388 128,088 0.11% Shares
CITADEL ADVISORS LLC $389,120 128,000 0.11% Put option
Virtus Investment Advisers, LLC $381,104 125,363 0.11% Shares
WEALTH EFFECTS LLC $372,856 122,650 0.10% Shares
LPL Financial LLC $370,734 121,952 0.10% Shares
MetLife Investment Management, LLC $355,242 116,856 0.10% Shares
PROFUND ADVISORS LLC $345,338 113,598 0.10% Shares
D. E. Shaw & Co., Inc. $340,285 111,936 0.10% Shares
Jefferies Financial Group Inc. $334,400 110,000 0.09% Shares
SILVERCREST ASSET MANAGEMENT GROUP LLC $314,640 103,500 0.09% Shares
Susquehanna Portfolio Strategies, LLC $314,257 103,374 0.09% Shares
Summit Financial Wealth Advisors, LLC $313,996 103,288 0.09% Shares
ADAR1 Capital Management, LLC $312,582 102,823 0.09% Shares
Mariner, LLC $307,407 101,123 0.09% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $304,000 100,000 0.09% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $278,276 91,538 0.08% Shares
CANADA PENSION PLAN INVESTMENT BOARD $265,392 87,300 0.07% Shares
Grantham, Mayo, Van Otterloo & Co. LLC $254,864 83,837 0.07% Shares
Invesco Ltd. $241,625 79,482 0.07% Shares
Vanguard Global Advisers, LLC $228,137 75,045 0.06% Shares
KINGSWOOD WEALTH ADVISORS, LLC $226,480 74,500 0.06% Shares
RENAISSANCE TECHNOLOGIES LLC $217,664 71,600 0.06% Shares
Bank of New York Mellon Corp $206,136 67,808 0.06% Shares
IEQ CAPITAL, LLC $203,540 66,954 0.06% Shares
PVG ASSET MANAGEMENT CORP $201,005 66,120 0.06% Shares
HSBC HOLDINGS PLC $199,504 64,460 0.06% Shares
Leonteq Securities AG $194,560 64,000 0.05% Shares
Police & Firemen's Retirement System of New Jersey $178,220 58,625 0.05% Shares
AXQ CAPITAL, LP $172,702 56,810 0.05% Shares
ENVESTNET ASSET MANAGEMENT INC $172,499 56,743 0.05% Shares
WOLVERINE TRADING, LLC $163,728 43,200 0.05% Put option
MERCER GLOBAL ADVISORS INC /ADV $161,470 53,115 0.05% Shares
Corient Private Wealth LP $161,219 53,032 0.05% Shares
NEW YORK STATE COMMON RETIREMENT FUND $160,351 52,747 0.05% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $158,189 52,036 0.04% Shares
Cetera Investment Advisers $157,779 51,901 0.04% Shares
JANE STREET GROUP, LLC $150,176 49,400 0.04% Put option
Caption Management, LLC $141,716 46,617 0.04% Shares
INTECH INVESTMENT MANAGEMENT LLC $139,569 45,911 0.04% Shares
Quantbot Technologies LP $138,721 45,632 0.04% Shares
Graham Capital Management, L.P. $136,618 44,940 0.04% Shares
AMERIPRISE FINANCIAL INC $135,639 44,618 0.04% Shares

Company insiders 48 insiders · 25 officers · 20 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Vipin K Garg President and CEO Feb. 2, 2025 M 355,082 0 0 $0
William Enright President and CEO May 25, 2018 P 365,839 0 0 $0
David P Wright President and CEO Dec. 11, 2009 P 399,500 0 0 $0
Gregory L Weaver Chief Financial Officer July 31, 2026 A 39,831 2 0 $49,200
Andrew Shutterly Acting Chief Financial Officer July 31, 2024 A 11,372 0 0 $0
Richard I Eisenstadt Chief Financial Officer Jan. 30, 2024 M 45,012 0 0 $0
William Michael Brown Chief Financial Officer July 31, 2021 A 17,721 0 0 $0
Elizabeth Czerepak CFO and EVP Corp. Development Sept. 22, 2017 A — 0 0 $0
MACNEILL PHILIP VP, CFO, Treasurer, Secretary Dec. 21, 2016 M 126,346 0 0 $0
Linda L Chang SVP, CFO & Secretary Jan. 7, 2015 M 30,000 0 0 $0
Charles A. Reinhart III SVP, Chief Financial Officer Dec. 8, 2010 A — 0 0 $0
Kevin Price President - PharmAthene UK,Ltd Jan. 21, 2009 A 2,500 0 0 $0
Jeffrey Michael Jones COO March 11, 2015 A 27,544 0 0 $0
Scot M Roberts Chief Scientific Officer July 31, 2026 A 113,699 0 0 $0
Christophe Arbet-Engels Chief Medical Officer Oct. 1, 2025 A — 0 0 $0
Linda M Richardson Chief Commercial Officer Sept. 16, 2025 A — 0 0 $0
Raymond M Jordt Chief Business Officer July 31, 2025 A 36,270 0 0 $0
Matthew Scott Harris Chief Medical Officer July 31, 2025 A 16,087 0 0 $0
Sybil Tasker Chief Medical Officer June 17, 2019 A — 0 0 $0
Wayne Morges SVP, Reg. Affairs & Quality Dec. 8, 2014 A 35,532 0 0 $0
Francesca M Cook SVP, Policy & Gov't Affairs Dec. 8, 2014 A 37,631 0 0 $0
Thomas Richard Fuerst EVP, Chief Scientific Officer Dec. 1, 2011 A 15,000 0 0 $0
Valerie D Riddle SVP, Medical Director May 31, 2011 M 44,436 0 0 $0
Joan Fusco SVP, Operations May 6, 2010 A 36,730 0 0 $0
Christopher C Camut VP, Gov't Contracts Jan. 21, 2010 F 46,777 0 0 $0
Mitchel Sayare Director May 1, 2026 A 26,363 0 0 $0
Teri L Lawver Director Sept. 25, 2025 A — 0 0 $0
Wayne Pisano Director Sept. 25, 2025 A 8,498 0 0 $0
Klaus Schafer Director Sept. 25, 2025 A 9,179 0 0 $0
Philip Hodges Director Sept. 25, 2025 A 8,731 0 0 $0
Catherine A. Sohn Director Sept. 25, 2025 A 1,000 0 0 $0
Diane Jorkasky Director Sept. 25, 2025 A 0 0 0 $0
John Gill Director Sept. 25, 2025 A 0 0 0 $0
David Drutz Director Aug. 19, 2024 M 55,524 0 0 $0
SCHAFFER DERACE L Director Dec. 29, 2017 P 589,453 0 0 $0
Jeffrey W. Runge Director Jan. 20, 2017 M 197,700 0 0 $0
Steven St Peter Director Jan. 4, 2017 M 205,004 0 0 $0
Eric I Richman Director Nov. 22, 2016 M 898,055 0 0 $0
Joel Mccleary Director Dec. 31, 2014 A 120,167 0 0 $0
Brian A Markison Director Dec. 31, 2014 A — 0 0 $0
John Pappajohn Director June 23, 2011 A 394,044 0 0 $0
CAVANAUGH JAMES H Director June 23, 2010 A — 0 0 $0
VELOCITY PHARMACEUTICAL HOLDINGS LLC 10% owner May 15, 2020 S 1,687,250 0 0 $0
Truffle Capital S.A.S. 10% owner Feb. 13, 2018 J 76,700 0 0 $0
ANSBERT GADICKE 10% owner Aug. 3, 2007 A — 0 0 $0
Jerome Benedict Durso — Aug. 13, 2026 P 62,500 1 0 $44,250
Jordan P Karp — Dec. 3, 2012 A 21,929 0 0 $0
Matthew P Kinley — Aug. 3, 2007 P 541,000 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 18 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, VHCP Management II, LLC, VHCP Management III, LLC, Shah, Nimish, Koh, Bong June 25, 2020 — Initial filing Passive investment SEC
Philip Hodges, Redmont Venture Partners, Inc., Redmont VAXN Capital Holdings, LLC, Paradigm Venture Partners, L.P. ×3 filings Oct. 19, 2017 — Initial filing — SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person March 30, 2016 — Initial filing — SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Feb. 12, 2016 — Initial filing — SEC
PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C., PRESCOTT GROUP AGGRESSIVE SMALL CAP, L.P., PRESCOTT GROUP AGGRESSIVE SMALL CAP II, L.P., PHIL FROHLICH ×6 filings Dec. 2, 2013 — Initial filing — SEC
Theraclone Sciences, Inc. Aug. 12, 2013 — Initial filing M&A / sale SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Dec. 27, 2010 — Initial filing Passive investment SEC
Kelisia Holdings L imited, Panacea Biotec Limited Sept. 18, 2009 — Initial filing — SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Aug. 4, 2009 — Initial filing Passive investment SEC
HealthCare Ventures VII, L.P., HealthCare Partners VII, L.P., James H. Cavanaugh, Ph.D., John Littlechild, Harold Werner, Augustine Lawlor, Christopher Mirabelli, Ph.D. ×3 filings Aug. 3, 2009 — Initial filing Passive investment SEC
Bear Stearns Health Innoventures, L.P., Bear Stearns Health Innoventures Offshore, L.P., BX, L.P., Bear Stearns Health Innoventures Employee Fund, L.P., BSHI Members, L.L.C., Bear Stearns Health Innoventures Management, L.L.C., Bear Stearns Asset Management Inc. ×3 filings May 29, 2009 — Initial filing Board campaign SEC
Integrated Core Strategies (US) LLC, Riverview Group LLC, Millennium Management LLC, Israel A. Englander ×2 filings April 23, 2009 — Initial filing — SEC
Nexia Biotechnologies Ltd. May 30, 2008 — Initial filing — SEC
Undisclosed reporting person Aug. 17, 2007 — Initial filing — SEC
Undisclosed reporting person Aug. 14, 2007 — Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 32 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.50% 36,663 SH Aug. 8, 2026 Daily
BBC · ETFis Series Trust I 0.36% 52,374 NS April 30, 2026 N-PORT
SBIO · ALPS ETF Trust 0.25% 134,076 NS May 31, 2026 N-PORT
IWC · iShares Trust 0.14% 673,112 SH Aug. 8, 2026 Daily
LABU · Direxion Shares ETF Trust 0.12% 248,923 NS April 30, 2026 N-PORT
IBB · iShares Trust 0.04% 1,339,073 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.04% 10,586 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.04% 172,834 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.04% 1,851,172 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 1,142,675 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 183,761 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.02% 4,631 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.02% 5,057,242 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 56,560 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 2,235,429 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.01% 6,144 NS May 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.01% 569,267 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 414,821 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.01% 4,804 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 4,861 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 122 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 358,663 SH Aug. 8, 2026 Daily
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,514 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 8,167 NS April 30, 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0.00% 763 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 23,287 SH Aug. 8, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 25,408 NS April 30, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 9,653 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 34,439 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 5,748,771 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 16,865 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 353 NS May 31, 2026 N-PORT