SLN Silence Therapeutics Plc - American Depository Share
$5.85
Price · May 20, 2026
Fundamentals as of May 7, 2026
52W Range
$4–$8
39% of range
Analyst Rating
—
Price Target
$31
+433% upside
P/E (TTM)
-9.7
ROE
-113.3%
Net Profit Margin
-15851.9%
SLN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$5.85
Market Cap
$862M
P/E (TTM)
-9.7
EPS (TTM)
$-0.63
Revenue (TTM)
$559.0K
Div Yield
—
ROE
-113.3%
Debt/Equity
—
52W Range
$4 – $8
SLN Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$559.0K
2022-12-31
→
2025-12-31
EPS
$-0.63
2022-12-31
→
2025-12-31
Free Cash Flow
$-62M
2025-12-31
→
2025-12-31
Margins
-15851.9%
2025-12-31
→
2025-12-31
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
SLN
Peer Median
P/E (TTM)
-9.7
—
P/S (TTM)
1541.2
13.4
P/B
13.8
1.7
Price / FCF
-13.8
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
SLN
Peer Median
Gross Margin
61.5%
66.0%
Operating Margin
-16292.8%
—
Net Profit Margin
-15851.9%
-662.1%
ROA
-53.0%
-59.3%
ROE
-113.3%
-98.1%
ROIC
-146.2%
—
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
SLN
Peer Median
Current Ratio
8.7
6.2
Quick Ratio
6.3
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
SLN
Peer Median
Revenue YoY
-98.7%
—
Revenue CAGR 3Y
-70.5%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
SLN
Peer Median
SLN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
12-Month Price Target
5 analysts · 2026-05-19
Median
$25.00
Mean
$31.20
Now
$5.85
Low
$4.00
High
$75.00
Median target
$25.00
+327.2%
Mean target
$31.20
+433.2%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| Dec. 31, 2024 | $0.21 | — | — |
| Dec. 31, 2023 | $-0.37 | — | — |
Peer Comparison Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| SLN | $862M | -9.7 | -98.7% | -15851.9% | -113.3% | 61.5% |
| AUTL | — | -1.8 | 644.9% | -381.4% | -109.6% | — |
| BCYC | $491M | -2.2 | 105.8% | -301.7% | -34.2% | — |
| TLSA | — | — | — | — | — | — |
| OKYO | — | — | — | — | — | — |
| ROIV | $7.02B | -42.0 | -11.2% | -592.0% | -3.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $559.0K | $43M | $32M | |
| Cost of Revenue | $215.0K | $12M | $13M | |
| Gross Profit | $344.0K | $31M | $19M | |
| R&D Expense | $68M | $68M | $57M | |
| SG&A Expense | $22M | $27M | $26M | |
| Operating Income | $-91M | $-63M | $-64M | |
| Pretax Income | $-89M | $-44M | $-53M | |
| Income Tax | $11.0K | $845.0K | $956.0K | |
| Net Income | $-89M | $-45M | $-54M | |
| EPS (Basic) | $-0.63 | $-0.33 | $-0.49 | |
| EPS (Diluted) | $-0.63 | $-0.33 | $-0.49 | |
| Shares (Basic) | 141,694,702 | 138,752,224 | 111,277,250 | |
| Shares (Diluted) | 141,694,702 | 138,752,224 | 111,277,250 | |
| EBITDA | $-91M | · | · |
Balance Sheet 21
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $11M | $121M | $69M | |
| Short-term Investments | $74M | $26M | · | |
| Receivables | $0 | $972.0K | $290.0K | |
| Other Current Assets | $12M | $15M | $12M | |
| Current Assets | $119M | $187M | $103M | |
| PP&E (Net) | $2M | $2M | $2M | |
| PP&E (Gross) | $6M | $6M | $6M | |
| Accum. Depreciation | $4M | $5M | $4M | |
| Goodwill | $11M | $9M | $10M | |
| Intangibles | $288.0K | $312.0K | · | |
| Other Non-current Assets | $127.0K | $4M | $4M | |
| Total Assets | $131M | $203M | $119M | |
| Current Liabilities | $14M | $17M | $22M | |
| Capital Leases | $71.0K | $0 | $118.0K | |
| Total Liabilities | $69M | $69M | $97M | |
| Common Stock | $10M | $10M | $9M | |
| Retained Earnings | $-563M | $-474M | $-432M | |
| AOCI | $-3M | $-12M | $-11M | |
| Stockholders' Equity | $62M | $134M | $22M | |
| Liabilities + Equity | $131M | $203M | $119M | |
| Shares Outstanding | 141,701,848 | 141,674,074 | 118,846,966 |
Cash Flow 11
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $8M | $16M | $16M | |
| Deferred Tax | $11.0K | $845.0K | $956.0K | |
| Restructuring | $1M | $0 | · | |
| Operating Cash Flow | $-62M | $-68M | $-49M | |
| CapEx | $55.0K | $211.0K | $56.0K | |
| Investing Cash Flow | $-48M | $-22M | $19M | |
| Stock Issued | $15.0K | $142M | $32M | |
| Net Stock Activity | $15.0K | · | · | |
| Financing Cash Flow | $15.0K | $142M | $32M | |
| Taxes Paid | $637.0K | $433.0K | $-801.0K | |
| Free Cash Flow | $-62M | · | · |
Profitability 8
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Gross Margin | 61.5% | · | · | |
| Operating Margin | -16292.8% | · | · | |
| Net Margin | -15851.9% | · | · | |
| Pretax Margin | -15849.9% | · | · | |
| EBITDA Margin | -16292.8% | · | · | |
| ROA | -53.0% | · | · | |
| ROE | -113.3% | · | · | |
| ROIC | -146.2% | · | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 8.7 | · | · | |
| Quick Ratio | 6.3 | · | · |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | |
| Receivables Turnover | 1.2 | · | · |
Growth Rates 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -98.7% | 36.7% | 46.1% | |
| Revenue CAGR 3Y | -70.5% | · | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $559.0K | $43M | · | |
| Net Income TTM | $-89M | $-45M | · | |
| Market Cap | $862M | · | · | |
| P/E | -9.7 | -20.8 | · | |
| P/S | 1541.2 | · | · | |
| P/B | 13.8 | · | · | |
| P / Tangible Book | 16.8 | 7.8 | · | |
| P / Cash Flow | -13.8 | · | · | |
| P / FCF | -13.8 | · | · | |
| Earnings Yield | -10.4% | -4.8% | · |
Income Statement 14
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $422.0K | $34.0K | $159.0K | $224.0K | $142.0K | $25M | $1M | $756.0K | $16M | |
| Cost of Revenue | $11.0K | $12.0K | $64.0K | $85.0K | $54.0K | $2M | $4M | $3M | $3M | |
| Gross Profit | $411.0K | $22.0K | $95.0K | $139.0K | $88.0K | $23M | $-2M | $-3M | $13M | |
| R&D Expense | $9M | $9M | $21M | $18M | $21M | $22M | $20M | $14M | $12M | |
| SG&A Expense | $7M | $4M | $6M | $5M | $8M | $6M | $8M | $7M | $7M | |
| Operating Income | $-16M | $-12M | $-26M | $-24M | $-28M | $-4M | $-30M | $-23M | $-6M | |
| Pretax Income | $-15M | $-12M | $-21M | $-27M | $-29M | $13M | $-35M | $-20M | $-2M | |
| Income Tax | $0 | $0 | $1.0K | $10.0K | $0 | $324.0K | $49.0K | $228.0K | $244.0K | |
| Net Income | $-15M | $-12M | $-21M | $-27M | $-29M | $12M | $-36M | $-20M | $-2M | |
| EPS (Basic) | $-0.11 | $-0.09 | $-0.15 | $-0.19 | $-0.20 | $0.08 | $-0.25 | $-0.14 | $-0.02 | |
| EPS (Diluted) | $-0.11 | $-0.09 | $-0.15 | $-0.19 | $-0.20 | $0.08 | $-0.25 | $-0.14 | $-0.02 | |
| Shares (Basic) | 141,702,578 | -283,381,927 | 141,701,848 | 141,696,047 | 141,678,734 | -274,535,983 | 141,198,163 | 140,208,929 | 131,881,115 | |
| Shares (Diluted) | 141,702,578 | -283,381,927 | 141,701,848 | 141,696,047 | 141,678,734 | -274,535,983 | 141,198,163 | 140,208,929 | 131,881,115 | |
| EBITDA | $-16M | · | $-26M | $-24M | $-28M | · | · | · | · |
Balance Sheet 21
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $6M | $11M | $82M | $42M | $65M | $121M | · | · | · | |
| Short-term Investments | $64M | $74M | $20M | $72M | $72M | $26M | · | · | · | |
| Receivables | $0 | $0 | $28.0K | $85.0K | $41.0K | $972.0K | · | · | · | |
| Other Current Assets | $11M | $12M | $9M | $14M | $16M | $15M | · | · | · | |
| Current Assets | $103M | $119M | $134M | $149M | $170M | $187M | · | · | · | |
| PP&E (Net) | $1M | $2M | $2M | $2M | $2M | $2M | · | · | · | |
| PP&E (Gross) | · | $6M | · | · | · | $6M | · | · | · | |
| Accum. Depreciation | · | $4M | · | · | · | $5M | · | · | · | |
| Goodwill | $10M | $11M | $11M | $11M | $10M | $9M | · | · | · | |
| Intangibles | · | $288.0K | · | · | · | $312.0K | · | · | · | |
| Other Non-current Assets | $127.0K | $127.0K | $399.0K | $4M | $4M | $4M | · | · | · | |
| Total Assets | $115M | $131M | $147M | $165M | $185M | $203M | · | · | · | |
| Current Liabilities | $10M | $14M | $17M | $15M | $19M | $17M | · | · | · | |
| Capital Leases | $43.0K | $71.0K | $97.0K | · | · | $0 | · | · | · | |
| Total Liabilities | $66M | $69M | $73M | $71M | $73M | $69M | · | · | · | |
| Common Stock | $10M | $10M | $10M | $10M | $10M | $10M | · | · | · | |
| Retained Earnings | $-578M | $-563M | $-551M | $-530M | $-503M | $-474M | · | · | · | |
| AOCI | $-3M | $-3M | $-3M | $-1M | $-8M | $-12M | · | · | · | |
| Stockholders' Equity | $49M | $62M | $74M | $94M | $113M | $134M | · | · | · | |
| Liabilities + Equity | $115M | $131M | $147M | $165M | $185M | $203M | · | · | · | |
| Shares Outstanding | 141,703,840 | 141,701,848 | 141,701,848 | 141,701,848 | 141,690,850 | 141,674,074 | · | · | · |
Cash Flow 11
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $2M | $-86.0K | $3M | $2M | $4M | $4M | $4M | $4M | $4M | |
| Deferred Tax | · | $0 | $1.0K | $10.0K | $0 | $324.0K | $49.0K | $228.0K | $244.0K | |
| Restructuring | · | $0 | $0 | $1M | · | $0 | $0 | $0 | · | |
| Operating Cash Flow | $-16M | $-17M | $-11M | $-22M | $-12M | $-27M | $-26M | $-5M | $-9M | |
| CapEx | $0 | $0 | $3.0K | $48.0K | $4.0K | $62.0K | $64.0K | $85.0K | $0 | |
| Investing Cash Flow | $10M | $-53M | $51M | $-2M | $-44M | $66M | $-38M | $-43.0K | $-50M | |
| Stock Issued | $0 | $0 | $0 | $1.0K | $14.0K | $-98.0K | $8M | $1M | $133M | |
| Net Stock Activity | $0 | · | · | · | $14.0K | · | · | · | · | |
| Financing Cash Flow | $0 | $0 | $0 | $1.0K | $14.0K | $-98.0K | $8M | $1M | $133M | |
| Taxes Paid | $-88.0K | $1M | $-121.0K | $-433.0K | $-76.0K | $759.0K | $-110.0K | $-107.0K | $-109.0K | |
| Free Cash Flow | $-16M | · | · | · | $-12M | · | · | · | · |
Profitability 8
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 97.4% | · | 59.8% | 62.1% | 62.0% | · | · | · | · | |
| Operating Margin | -3729.2% | · | -16505.7% | -10697.8% | -20006.3% | · | · | · | · | |
| Net Margin | -3544.3% | · | -13181.1% | -12211.6% | -20091.5% | · | · | · | · | |
| Pretax Margin | -3544.3% | · | -13180.5% | -12207.1% | -20091.5% | · | · | · | · | |
| EBITDA Margin | -3729.2% | · | -16505.7% | -10697.8% | -20006.3% | · | · | · | · | |
| ROA | -10.0% | · | -28.6% | -33.1% | -30.8% | · | · | · | · | |
| ROE | -18.4% | · | -56.6% | -58.1% | -50.6% | · | · | · | · | |
| ROIC | -31.9% | · | -35.4% | -25.5% | -25.2% | · | · | · | · |
Liquidity & Solvency 2
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.8 | · | 7.7 | 10.1 | 8.8 | · | · | · | · | |
| Quick Ratio | 6.7 | · | 5.9 | 7.7 | 7.1 | · | · | · | · |
Efficiency 2
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · | |
| Receivables Turnover | 20.6 | · | 11.4 | 5.3 | 6.9 | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $947.0K | · | $2M | $3M | $18M | · | · | · | · | |
| Net Income TTM | $-92M | · | $-112M | $-111M | $-86M | · | · | · | · | |
| Market Cap | $747M | · | $735M | $822M | $400M | · | · | · | · | |
| P/E | -8.1 | · | -6.6 | -7.4 | -4.6 | · | · | · | · | |
| P/S | 788.6 | · | 363.5 | 313.7 | 22.1 | · | · | · | · | |
| P/B | 15.1 | · | 9.9 | 8.7 | 3.5 | · | · | · | · | |
| P / Tangible Book | 19.1 | · | 11.6 | 9.8 | 3.9 | · | · | · | · | |
| P / Cash Flow | -47.9 | · | · | · | -32.5 | · | · | · | · | |
| P / FCF | -47.9 | · | · | · | -32.5 | · | · | · | · | |
| Earnings Yield | -12.3% | · | -15.2% | -13.5% | -21.6% | · | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Revenue | $559.0K | $43M | $32M | $22M |
| Gross Margin % | 61.5% | — | — | — |
| Operating Margin % | -16292.8% | — | — | — |
| Net Income | $-89M | $-45M | $-54M | $-50M |
| Diluted EPS | $-0.63 | $-0.33 | $-0.49 | $-0.52 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Current Ratio | 8.7 | — | — | — |
| Quick Ratio | 6.3 | — | — | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Free Cash Flow | $-62M | — | — | — |
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