SLN — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Siren, L.L.C. | $36,359,589 | 3,311,438 | 14.83% | Shares |
| TCG Crossover Management, LLC | $33,308,489 | 3,033,560 | 13.58% | Shares |
| Redmile Group, LLC | $23,769,251 | 2,164,777 | 9.69% | Shares |
| Nantahala Capital Management, LLC | $14,787,106 | 1,346,731 | 6.03% | Shares |
| CITADEL ADVISORS LLC | $14,599,282 | 1,329,625 | 5.95% | Shares |
| Nextech Invest Ltd. | $10,457,352 | 952,400 | 4.26% | Shares |
| MILLENNIUM MANAGEMENT LLC | $9,983,883 | 909,279 | 4.07% | Shares |
| Tetragon Partners GP Ltd | $8,391,531 | 764,256 | 3.42% | Shares |
| Soleus Capital Management, L.P. | $6,917,400 | 630,000 | 2.82% | Shares |
| Balyasny Asset Management L.P. | $6,708,560 | 610,980 | 2.74% | Shares |
| 5AM Venture Management, LLC | $5,228,676 | 476,200 | 2.13% | Shares |
| GREAT POINT PARTNERS LLC | $4,941,000 | 450,000 | 2.02% | Shares |
| MORGAN STANLEY | $4,426,828 | 403,172 | 1.81% | Shares |
| AMERIPRISE FINANCIAL INC | $4,063,171 | 370,052 | 1.66% | Shares |
| JANE STREET GROUP, LLC | $4,053,278 | 369,151 | 1.65% | Shares |
| ADAR1 Capital Management, LLC | $3,715,336 | 338,373 | 1.52% | Shares |
| SummitTX Capital, L.P. | $3,586,595 | 326,648 | 1.46% | Shares |
| Tetragon Partners GP Ltd | $3,294,000 | 300,000 | 1.34% | Call option |
| Caption Management, LLC | $3,270,942 | 297,900 | 1.33% | Call option |
| Schonfeld Strategic Advisors LLC | $2,957,439 | 269,348 | 1.21% | Shares |
| UBS Group AG | $2,669,809 | 243,152 | 1.09% | Shares |
| Ishara Investments LP | $2,434,847 | 55,350 | 0.99% | Shares |
| BlackRock, Inc. | $2,414,689 | 219,917 | 0.98% | Shares |
| BANK OF MONTREAL /CAN/ | $2,215,039 | 201,734 | 0.90% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,177,850 | 198,347 | 0.89% | Shares |
| Propel Bio Management, LLC | $2,105,228 | 191,733 | 0.86% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,026,019 | 184,519 | 0.83% | Shares |
| FRED ALGER MANAGEMENT, LLC | $1,943,460 | 177,000 | 0.79% | Shares |
| Ikarian Capital, LLC | $1,827,725 | 830,784 | 0.75% | Shares |
| Qube Research & Technologies Ltd | $1,800,116 | 163,945 | 0.73% | Shares |
| Caption Management, LLC | $1,783,986 | 162,476 | 0.73% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,745,271 | 158,950 | 0.71% | Shares |
| GOLDMAN SACHS GROUP INC | $1,712,100 | 155,929 | 0.70% | Shares |
| TWO SIGMA INVESTMENTS, LP | $1,328,624 | 121,004 | 0.54% | Shares |
| HSBC HOLDINGS PLC | $1,324,151 | 122,834 | 0.54% | Shares |
| Quadrature Capital Ltd | $1,297,056 | 118,129 | 0.53% | Shares |
| Squarepoint Ops LLC | $1,272,780 | 115,918 | 0.52% | Shares |
| XTX Topco Ltd | $1,181,217 | 107,579 | 0.48% | Shares |
| M28 Capital Management LP | $1,111,209 | 101,203 | 0.45% | Shares |
| MARSHALL WACE, LLP | $790,989 | 72,039 | 0.32% | Shares |
| Birchview Capital, LP | $781,974 | 71,218 | 0.32% | Shares |
| Seven Fleet Capital Management LP | $659,975 | 60,107 | 0.27% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $327,204 | 29,800 | 0.13% | Put option |
| GEODE CAPITAL MANAGEMENT, LLC | $324,327 | 29,538 | 0.13% | Shares |
| BANK OF AMERICA CORP /DE/ | $277,574 | 25,280 | 0.11% | Shares |
| Trexquant Investment LP | $261,785 | 23,842 | 0.11% | Shares |
| Verdad Advisers, LP | $223,992 | 20,400 | 0.09% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $213,012 | 19,400 | 0.09% | Call option |
| Scientech Research LLC | $210,080 | 19,133 | 0.09% | Shares |
| JANE STREET GROUP, LLC | $202,032 | 18,400 | 0.08% | Call option |
| RENAISSANCE TECHNOLOGIES LLC | $185,891 | 16,930 | 0.08% | Shares |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $179,347 | 16,334 | 0.07% | Shares |
| Persistent Asset Partners Ltd | $166,567 | 15,170 | 0.07% | Shares |
| RAYMOND JAMES FINANCIAL INC | $164,700 | 15,000 | 0.07% | Shares |
| RHUMBLINE ADVISERS | $151,680 | 13,815 | 0.06% | Shares |
| CITIGROUP INC | $145,123 | 13,217 | 0.06% | Shares |
| AXQ CAPITAL, LP | $137,975 | 12,566 | 0.06% | Shares |
| GAMMA Investing LLC | $121,472 | 11,063 | 0.05% | Shares |
| CenterBook Partners LP | $114,368 | 10,416 | 0.05% | Shares |
| TWO SIGMA ADVISERS, LP | $96,672 | 15,900 | 0.04% | Shares |
| China Universal Asset Management Co., Ltd. | $82,076 | 7,475 | 0.03% | Shares |
| JPMORGAN CHASE & CO | $41,682 | 3,863 | 0.02% | Shares |
| BARCLAYS PLC | $37,530 | 3,418 | 0.02% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $25,350 | 2,500 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $23,069 | 2,101 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $17,996 | 1,639 | 0.01% | Shares |
| Parallel Advisors, LLC | $14,274 | 1,300 | 0.01% | Shares |
| Rialto Wealth Management, LLC | $11,211 | 1,021 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $10,706 | 975 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $1,098 | 100 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $494 | 45 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $450 | 41 | 0.00% | Shares |
| HRT FINANCIAL LP | $337 | 30,748 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $307 | 28 | 0.00% | Shares |
| Virtu Financial LLC | $282 | 25,641 | 0.00% | Shares |
| SG Americas Securities, LLC | $132 | 12,056 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $129 | 11,836 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $0 | 26 | 0.00% | Shares |