SGMT Sagimet Biosciences Inc. - Series A Common Stock
$10.87
Price · Aug 19, 2026
Fundamentals as of Aug 11, 2026
52W Range
$4–$11
96% of range
Analyst Rating
BUY
18 analysts
Price Target
$29
+163% upside
P/E (TTM)
-3.7
ROE
-42.3%
Net Profit Margin
—
SGMT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$10.87
Market Cap
—
P/E (TTM)
-3.7
EPS (TTM)
$-1.58
Revenue (TTM)
$2M
Div Yield
—
ROE
-42.3%
Debt/Equity
—
52W Range
$5 – $11
SGMT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$2M
2023-12-31
→
2023-12-31
EPS
$-1.58
2022-12-31
→
2025-12-31
Free Cash Flow
—
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
SGMT
Peer Median
P/E (TTM)
-3.7
19.6
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
SGMT
Peer Median
ROA
-36.9%
-40.3%
ROE
-42.3%
-42.4%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
SGMT
Peer Median
Current Ratio
22.8
5.4
Quick Ratio
22.2
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
SGMT
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
SGMT
Peer Median
SGMT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
18 analysts
- Strong Buy 6 33.3%
- Buy 10 55.6%
- Hold 2 11.1%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
10 analysts · 2026-08-17
Median
$28.50
Now
$10.87
Low
$8.00
High
$56.00
Median target
$28.50
+162.3%
Mean target
$28.60
+163.2%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.10%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.33 | $-0.38 | 0.05% |
| Dec. 31, 2025 | $-0.29 | $-0.41 | 0.12% |
| Sept. 30, 2025 | $-0.40 | $-0.39 | -0.01% |
| June 30, 2025 | $-0.32 | $-0.52 | 0.20% |
| March 31, 2025 | $-0.56 | $-0.68 | 0.12% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| SGMT | — | -3.7 | — | — | -42.3% | — |
| IRWD | $550M | 22.5 | -15.7% | 8.1% | -8.5% | — |
| GYRE | $645M | 353.0 | 10.2% | 8.5% | 11.7% | — |
| ALLO | $314M | -1.6 | -76.8% | — | -59.9% | — |
| TECX | $391M | -5.2 | — | — | -27.7% | — |
| CBIO | $327M | -24.2 | -86.7% | -1419.6% | -90.0% | — |
| ASMB | $539M | -61.8 | 153.5% | -8.5% | -5.5% | — |
| NVCT | $194M | -5.7 | — | — | -149.9% | — |
| MDXG | $1.00B | 21.2 | 20.0% | 11.6% | 20.5% | 82.6% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 13
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | · | · | $2M | |
| R&D Expense | $39M | $38M | $20M | |
| SG&A Expense | $18M | $16M | $13M | |
| Operating Expenses | $57M | $54M | $33M | |
| Operating Income | $-57M | $-54M | $-31M | |
| Other Non-op | $6M | $9M | $3M | |
| Income Tax | $0 | $0 | · | |
| Net Income | $-51M | $-46M | $-28M | |
| EPS (Basic) | $-1.58 | $-1.45 | $-2.66 | |
| EPS (Diluted) | $-1.58 | $-1.45 | $-2.66 | |
| Shares (Basic) | 32,345,525 | 31,350,725 | 10,460,335 | |
| Shares (Diluted) | 32,345,525 | 31,350,725 | 10,460,335 | |
| EBITDA | $-57M | $-54M | $-31M |
Balance Sheet 18
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $35M | $76M | $75M | |
| Short-term Investments | $78M | $75M | $20M | |
| Prepaid Expense | $3M | $2M | $2M | |
| Other Current Assets | $199.0K | $157.0K | $74.0K | |
| Current Assets | $116M | $153M | $97M | |
| Other Non-current Assets | $0 | · | · | |
| Total Assets | $116M | $160M | $97M | |
| Accounts Payable | $1M | $1M | $186.0K | |
| Accrued Liabilities | $4M | $3M | $5M | |
| Current Liabilities | $5M | $4M | $6M | |
| Capital Leases | $0 | · | · | |
| Total Liabilities | $5M | $4M | $6M | |
| Paid-in Capital | $458M | $451M | $341M | |
| Retained Earnings | $-346M | $-295M | $-250M | |
| AOCI | $120.0K | $230.0K | $30.0K | |
| Stockholders' Equity | $111M | $156M | $91M | |
| Liabilities + Equity | $116M | $160M | $97M | |
| Shares Outstanding | · | · | 0 |
Cash Flow 6
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $6M | $5M | $5M | |
| Operating Cash Flow | $-46M | $-42M | $-24M | |
| Investing Cash Flow | $5M | $-62M | $13M | |
| Stock Issued | $0 | $106M | · | |
| Net Stock Activity | $0 | $106M | · | |
| Financing Cash Flow | $275.0K | $105M | $86M |
Profitability 5
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | · | · | -1537.0% | |
| Net Margin | · | · | -1393.8% | |
| EBITDA Margin | · | · | -1537.0% | |
| ROA | -36.9% | -35.5% | -43.0% | |
| ROE | -42.3% | -27.9% | -29.5% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 22.8 | 34.3 | 17.1 | |
| Quick Ratio | 22.2 | 34.0 | 16.8 |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | · | · | 0.0 |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | · | · | $2M | |
| Net Income TTM | $-51M | $-46M | $-28M | |
| Market Cap | · | · | $0 | |
| P/E | -3.7 | -3.1 | -2.0 | |
| P/S | · | · | 0.0 | |
| P / Tangible Book | · | · | 0.0 | |
| P / Cash Flow | · | · | 0.0 | |
| Earnings Yield | -26.7% | -32.2% | -49.1% |
Income Statement 12
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | · | · | $0 | $2M | |
| R&D Expense | $12M | $7M | $7M | $10M | $7M | $15M | $14M | $13M | $6M | $5M | $6M | $5M | |
| SG&A Expense | $4M | $5M | $4M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | |
| Operating Expenses | $16M | $12M | $11M | $14M | $12M | $20M | $18M | $17M | $11M | $9M | $9M | $9M | |
| Operating Income | $-16M | $-12M | $-11M | $-14M | $-12M | $-20M | $-18M | $-17M | $-11M | $-9M | $-9M | $-7M | |
| Other Non-op | $2M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | |
| Net Income | $-14M | $-11M | $-10M | $-13M | $-10M | $-18M | $-16M | $-15M | $-8M | $-7M | $-8M | $-6M | |
| EPS (Basic) | $-0.26 | $-0.33 | $-0.30 | $-0.40 | $-0.32 | $-0.56 | $-0.52 | $-0.45 | $-0.25 | $-0.23 | $69.07 | $-0.35 | |
| EPS (Diluted) | $-0.26 | $-0.33 | $-0.30 | $-0.40 | $-0.32 | $-0.56 | $-0.52 | $-0.45 | $-0.25 | $-0.23 | $69.07 | $-0.35 | |
| Shares (Basic) | 53,114,533 | 32,559,704 | -64,510,079 | 32,464,893 | 32,195,366 | 32,195,345 | -61,745,925 | 32,143,336 | 31,913,887 | 29,039,427 | -8,109,004 | 18,194,682 | |
| Shares (Diluted) | 53,114,533 | 32,559,704 | -64,510,079 | 32,464,893 | 32,195,366 | 32,195,345 | -61,745,925 | 32,143,336 | 31,913,887 | 29,039,427 | -8,109,004 | 18,194,682 | |
| EBITDA | $-16M | $-12M | · | $-14M | $-12M | $-20M | · | $-17M | $-11M | $-9M | · | $-7M |
Balance Sheet 18
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $166M | $37M | $35M | $32M | $42M | $65M | $76M | $77M | $96M | $177M | $75M | $102M | |
| Short-term Investments | $74M | $68M | $78M | $84M | $83M | $80M | $75M | $75M | $70M | $17M | $20M | $0 | |
| Prepaid Expense | $4M | $3M | $3M | $3M | $2M | $2M | $2M | $5M | $378.0K | $786.0K | $2M | $974.0K | |
| Other Current Assets | $226.0K | $248.0K | $199.0K | $253.0K | $173.0K | $263.0K | $157.0K | $101.0K | $130.0K | $108.0K | $74.0K | $77.0K | |
| Current Assets | $244M | $108M | $116M | $119M | $127M | $146M | $153M | $157M | $167M | $194M | $97M | $103M | |
| Other Non-current Assets | $55.0K | · | · | · | · | $62.0K | · | · | · | · | · | · | |
| Total Assets | $263M | $108M | $116M | $128M | $137M | $146M | $160M | $175M | $189M | $195M | $97M | $103M | |
| Accounts Payable | $1M | $2M | $1M | $4M | $2M | $3M | $1M | $1M | $2M | $531.0K | $186.0K | $2M | |
| Accrued Liabilities | $4M | $3M | $4M | $5M | $5M | $4M | $3M | $3M | $4M | $4M | $5M | $3M | |
| Current Liabilities | $5M | $5M | $5M | $9M | $7M | · | $4M | · | · | · | $6M | $5M | |
| Capital Leases | $2M | · | · | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $7M | · | · | · | · | $7M | · | $4M | $6M | $5M | · | $5M | |
| Paid-in Capital | $627M | $459M | $458M | $456M | $454M | $452M | $451M | $449M | $448M | $446M | $341M | $339M | |
| Retained Earnings | $-371M | $-357M | $-346M | $-337M | $-324M | $-313M | $-295M | $-279M | $-264M | $-256M | $-250M | $-242M | |
| AOCI | $-77.0K | $8.0K | $120.0K | $117.0K | $76.0K | $121.0K | $230.0K | $441.0K | $-23.0K | $7.0K | $30.0K | · | |
| Stockholders' Equity | $256M | $102M | $111M | $119M | $130M | $139M | $156M | $171M | $183M | $190M | $91M | $98M | |
| Liabilities + Equity | $263M | $108M | $116M | $128M | $137M | $146M | $160M | $175M | $189M | $195M | $97M | $103M | |
| Shares Outstanding | · | · | · | · | · | · | · | · | · | · | 0 | 0 |
Cash Flow 6
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $4M | $2M | $2M | $2M | $2M | $1M | $2M | $2M | $1M | $759.0K | $1M | $2M | |
| Operating Cash Flow | $-11M | $-9M | $-12M | $-10M | $-9M | $-15M | $-11M | $-20M | $-6M | $-6M | $-7M | $-4M | |
| Investing Cash Flow | $-24M | $10M | $14M | $75.0K | $-13M | $3M | $10M | $624.0K | $-75M | $3M | $-20M | $0 | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | $0 | $106M | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $106M | · | · | |
| Financing Cash Flow | · | · | $0 | $274.0K | · | · | $0 | $0 | $-27.0K | $105M | $0 | $87M |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | · | · | · | -372.6% | |
| Net Margin | · | · | · | · | · | · | · | · | · | · | · | -317.6% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | · | · | · | -372.6% | |
| ROA | -7.0% | -8.4% | · | -8.5% | -6.4% | -10.7% | · | -10.5% | -7.7% | -6.8% | · | -12.3% | |
| ROE | -7.2% | -8.8% | · | -8.9% | -6.6% | -11.1% | · | -10.9% | 107.4% | -7.0% | · | -13.0% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 45.0 | 20.3 | · | 13.1 | 17.6 | · | · | · | · | · | · | 20.4 | |
| Quick Ratio | 44.3 | 19.7 | · | 12.8 | 17.3 | · | · | · | · | · | · | 20.2 |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.0 |
Valuation (TTM) 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-48M | $-52M | · | $-56M | $-51M | $-48M | · | $-36M | $-28M | $-26M | · | $-27M | |
| Market Cap | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| P/E | -5.9 | -3.2 | · | -4.0 | -4.8 | -2.2 | · | -2.2 | -0.1 | -0.1 | · | -0.1 | |
| P / Tangible Book | · | · | · | · | · | · | · | · | · | · | · | 0.0 | |
| Earnings Yield | -17.0% | -30.8% | · | -25.2% | -20.7% | -45.7% | · | -46.2% | -1071.0% | -1327.7% | · | -1273.5% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Revenue | — | — | $2M | — |
| Operating Margin % | — | — | -1537.0% | — |
| Net Income | $-51M | $-46M | $-28M | $-30M |
| Diluted EPS | $-1.58 | $-1.45 | $-2.66 | $-165.20 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Current Ratio | 22.8 | 34.3 | 17.1 | — |
| Quick Ratio | 22.2 | 34.0 | 16.8 | — |
Latest News Recent headlines mentioning this company
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Institutional owners (13F) 133 filers · $343.0M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 61 (+46 vs prior Q) | 23 (+12 vs prior Q) | 32 (-1 vs prior Q) | 16 (-3 vs prior Q) | +33.1M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Balyasny Asset Management L.P. | $28,029,853 | 3,626,113 | 8.17% | Shares |
| Woodline Partners LP | $23,195,040 | 3,000,652 | 6.76% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $22,631,106 | 2,927,698 | 6.60% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $19,837,283 | 2,566,272 | 5.78% | Shares |
| BVF INC/IL | $19,325,000 | 2,500,000 | 5.63% | Shares |
| Caligan Partners LP | $19,325,000 | 2,500,000 | 5.63% | Shares |
| Affinity Asset Advisors, LLC | $19,308,489 | 2,497,864 | 5.63% | Shares |
| FEDERATED HERMES, INC. | $16,104,164 | 2,083,333 | 4.69% | Shares |
| GREAT POINT PARTNERS LLC | $15,691,382 | 2,029,933 | 4.57% | Shares |
| STATE STREET CORP | $15,422,061 | 1,995,092 | 4.50% | Shares |
| Saturn V Capital Management LP | $11,439,766 | 1,479,918 | 3.33% | Shares |
| Blue Owl Capital Holdings LP | $9,744,005 | 1,260,544 | 2.84% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $9,537,080 | 1,233,409 | 2.78% | Shares |
| BAKER BROS. ADVISORS LP | $7,366,659 | 952,996 | 2.15% | Shares |
| MILLENNIUM MANAGEMENT LLC | $7,243,203 | 937,025 | 2.11% | Shares |
| Aberdeen Group plc | $6,552,721 | 847,700 | 1.91% | Shares |
| VANGUARD GROUP INC | $6,414,302 | 1,083,497 | 1.87% | Shares |
| HHLR ADVISORS, LTD. | $5,602,704 | 724,800 | 1.63% | Shares |
| GOLDMAN SACHS GROUP INC | $5,303,367 | 686,076 | 1.55% | Shares |
| AMERIPRISE FINANCIAL INC | $4,492,807 | 581,217 | 1.31% | Shares |
| Vestal Point Capital, LP | $4,139,044 | 535,452 | 1.21% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $3,587,454 | 464,095 | 1.05% | Shares |
| ADAR1 Capital Management, LLC | $3,381,875 | 437,500 | 0.99% | Shares |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $3,207,950 | 415,000 | 0.94% | Shares |
| Seven Fleet Capital Management LP | $3,119,403 | 403,545 | 0.91% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3,118,916 | 403,482 | 0.91% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,098,478 | 400,838 | 0.90% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $2,848,876 | 368,548 | 0.83% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $2,681,746 | 346,927 | 0.78% | Shares |
| Atom Investors LP | $2,674,719 | 346,018 | 0.78% | Shares |
| RAYMOND JAMES FINANCIAL INC | $2,551,078 | 330,023 | 0.74% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,236,289 | 289,300 | 0.65% | Call option |
| Rock Springs Capital Management LP | $1,932,500 | 250,000 | 0.56% | Shares |
| Palo Alto Investors LP | $1,932,500 | 250,000 | 0.56% | Shares |
| BARCLAYS PLC | $1,722,144 | 222,787 | 0.50% | Shares |
| Pale Fire Capital SE | $1,715,094 | 221,875 | 0.50% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1,712,512 | 221,541 | 0.50% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,440,872 | 186,400 | 0.42% | Put option |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,359,491 | 175,872 | 0.40% | Shares |
| UBS Group AG | $1,341,719 | 173,573 | 0.39% | Shares |
| Sofinnova Investments, Inc. | $1,288,336 | 166,667 | 0.38% | Shares |
| Driehaus Capital Management LLC | $1,288,336 | 166,667 | 0.38% | Shares |
| BlackRock, Inc. | $1,181,152 | 152,801 | 0.34% | Shares |
| CITADEL ADVISORS LLC | $1,035,047 | 133,900 | 0.30% | Put option |
| Propel Bio Management, LLC | $973,037 | 125,878 | 0.28% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $927,878 | 120,036 | 0.27% | Shares |
| BANK OF AMERICA CORP /DE/ | $699,603 | 90,505 | 0.20% | Shares |
| TWO SIGMA INVESTMENTS, LP | $633,102 | 81,902 | 0.18% | Shares |
| AWM Investment Company, Inc. | $618,400 | 80,000 | 0.18% | Shares |
| AMERICAN CENTURY COMPANIES INC | $588,214 | 76,095 | 0.17% | Shares |
| RHUMBLINE ADVISERS | $574,632 | 74,339 | 0.17% | Shares |
| Bank of New York Mellon Corp | $550,886 | 71,266 | 0.16% | Shares |
| DUMAC, INC. | $550,314 | 71,192 | 0.16% | Shares |
| Kestra Advisory Services, LLC | $513,380 | 66,414 | 0.15% | Shares |
| RB Capital Management, LLC | $506,825 | 97,000 | 0.15% | Shares |
| JANE STREET GROUP, LLC | $411,236 | 53,200 | 0.12% | Put option |
| WELLS FARGO & COMPANY/MN | $406,938 | 52,644 | 0.12% | Shares |
| CITADEL ADVISORS LLC | $397,322 | 51,400 | 0.12% | Call option |
| Hudson Bay Capital Management LP | $384,823 | 49,783 | 0.11% | Shares |
| CITIGROUP INC | $382,233 | 49,448 | 0.11% | Shares |
| Quadrature Capital Ltd | $367,979 | 47,604 | 0.11% | Shares |
| Dynamic Technology Lab Private Ltd | $331,000 | 42,770 | 0.10% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $310,746 | 40,200 | 0.09% | Shares |
| Mariner, LLC | $299,924 | 38,800 | 0.09% | Shares |
| FOX RUN MANAGEMENT, L.L.C. | $284,603 | 36,818 | 0.08% | Shares |
| MetLife Investment Management, LLC | $275,822 | 35,682 | 0.08% | Shares |
| Rafferty Asset Management, LLC | $211,230 | 27,326 | 0.06% | Shares |
| LPL Financial LLC | $206,778 | 26,750 | 0.06% | Shares |
| Cubist Systematic Strategies, LLC | $189,761 | 27,662 | 0.06% | Shares |
| Invesco Ltd. | $181,129 | 23,432 | 0.05% | Shares |
| SummitTX Capital, L.P. | $175,564 | 22,712 | 0.05% | Shares |
| D. E. Shaw & Co., Inc. | $171,428 | 22,177 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $168,189 | 21,758 | 0.05% | Shares |
| Composition Wealth, LLC | $165,236 | 21,376 | 0.05% | Shares |
| Cresset Asset Management, LLC | $155,211 | 20,079 | 0.05% | Shares |
| Steward Partners Investment Advisory, LLC | $148,277 | 19,182 | 0.04% | Shares |
| Abacus Planning Group, Inc. | $139,635 | 18,064 | 0.04% | Shares |
| RPG Investment Advisory, LLC | $134,116 | 17,350 | 0.04% | Shares |
| Police & Firemen's Retirement System of New Jersey | $133,969 | 17,331 | 0.04% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $125,226 | 16,200 | 0.04% | Shares |
| Baird Financial Group, Inc. | $121,183 | 15,677 | 0.04% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $118,331 | 15,308 | 0.03% | Shares |
| 1492 Capital Management LLC | $115,950 | 15,000 | 0.03% | Shares |
| SEI INVESTMENTS CO | $114,999 | 14,877 | 0.03% | Shares |
| Nuveen, LLC | $114,999 | 14,877 | 0.03% | Shares |
| JANE STREET GROUP, LLC | $112,858 | 14,600 | 0.03% | Call option |
| PROFUND ADVISORS LLC | $112,108 | 14,503 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $108,993 | 14,100 | 0.03% | Shares |
| Man Group plc | $107,107 | 13,856 | 0.03% | Shares |
| Cetera Investment Advisers | $100,490 | 13,000 | 0.03% | Shares |
| Jasper Ridge Partners, L.P. | $99,446 | 12,865 | 0.03% | Shares |
| ALLIANCEBERNSTEIN L.P. | $95,095 | 18,200 | 0.03% | Shares |
| NATIONS FINANCIAL GROUP INC, /IA/ /ADV | $92,760 | 12,000 | 0.03% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $92,258 | 11,935 | 0.03% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $89,908 | 11,631 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $84,644 | 10,950 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $81,436 | 10,535 | 0.02% | Shares |
| Persistent Asset Partners Ltd | $80,152 | 10,369 | 0.02% | Shares |
| PFG Investments, LLC | $77,300 | 10,000 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $75,275 | 9,738 | 0.02% | Shares |
Company insiders 21 insiders · 7 officers · 10 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| David Happel | President & CEO | July 20, 2026 S | 741,570 | 0 | 2 | $-561,897 |
| Thierry Chauche | Chief Financial Officer | May 28, 2026 A | 59,688 | 0 | 1 | $-7,032 |
| Dennis Hom | Chief Financial Officer | July 18, 2023 A | — | 0 | 0 | $0 |
| Anthony M Rimac | Chief Operating Officer | July 18, 2023 A | — | 0 | 0 | $0 |
| Elizabeth Rozek | Chief Legal & Admin. Officer | July 20, 2026 S | 224,414 | 0 | 2 | $-95,883 |
| Andreas Grauer | Chief Medical Officer | May 28, 2026 A | — | 0 | 0 | $0 |
| Eduardo Bruno Martins | Chief Medical Officer | Feb. 19, 2026 A | 147,296 | 0 | 1 | $-19,510 |
| Jennifer Jarrett | Director | June 12, 2026 A | — | 0 | 0 | $0 |
| Anne M. Phillips | Director | June 12, 2026 A | — | 0 | 0 | $0 |
| Paul W. Hoelscher | Director | June 12, 2026 A | — | 0 | 0 | $0 |
| Elizabeth A Grammer | Director | June 12, 2026 A | — | 0 | 0 | $0 |
| Beth C Seidenberg | Director | June 12, 2026 A | 46,875 | 0 | 0 | $0 |
| Timothy P Walbert | Director | June 9, 2025 A | — | 0 | 0 | $0 |
| Merdad Parsey | Director | June 5, 2024 A | 12,794 | 0 | 0 | $0 |
| Jinzi Jason Wu | Director | July 18, 2023 A | 1,654,701 | 0 | 0 | $0 |
| Richard J Rodgers | Director | July 18, 2023 A | — | 0 | 0 | $0 |
| New Enterprise Associates 13, L.P. | 10% owner | Jan. 29, 2024 J | 3,000,275 | 0 | 0 | $0 |
| Forest Baskett | 10% owner | Jan. 29, 2024 J | 11,300 | 0 | 0 | $0 |
| Scott D. Sandell | 10% owner | Jan. 29, 2024 J | 6,997 | 0 | 0 | $0 |
| Patrick J. Kerins | 10% owner | Jan. 29, 2024 J | 13,139 | 0 | 0 | $0 |
| George Kemble | — | Aug. 14, 2026 M | 62,161 | 0 | 4 | $-4,222,044 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 21 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0.12% | 199,515 SH | Aug. 8, 2026 | Daily |
| IBB · iShares Trust | 0.04% | 427,152 SH | Aug. 8, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.04% | 3,297 SH | Aug. 8, 2026 | Daily |
| IWO · iShares Trust | 0.03% | 421,047 SH | Aug. 8, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.02% | 49,546 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.02% | 73,083 NS | May 31, 2026 | N-PORT |
| IWM · iShares Trust | 0.02% | 1,467,173 SH | Aug. 8, 2026 | Daily |
| BIB · ProShares Trust | 0.01% | 1,147 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 658,772 SH | Aug. 8, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.01% | 337,803 SH | Aug. 8, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.01% | 11,145 SH | Aug. 8, 2026 | Daily |
| IWN · iShares Trust | 0.01% | 117,555 SH | Aug. 8, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.01% | 104,899 NS | April 30, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.00% | 2,377 NS | April 30, 2026 | N-PORT |
| IWV · iShares Trust | 0.00% | 24,928 SH | Aug. 8, 2026 | Daily |
| DFSU · Dimensional ETF Trust | 0.00% | 2,817 NS | April 30, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 3,445 NS | April 30, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 8,721 NS | April 30, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 1,776 NS | April 30, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1,861,227 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 4,988 SH | Aug. 8, 2026 | Daily |