CBIO — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $74,403,252 | 4,133,514 | 14.14% | Shares |
| BVF INC/IL | $49,477,734 | 2,748,763 | 9.40% | Shares |
| Fairmount Funds Management LLC | $49,461,588 | 2,747,866 | 9.40% | Shares |
| Venrock Adviser, LLC | $38,404,368 | 2,133,576 | 7.30% | Shares |
| Logos Global Management LP | $34,200,000 | 1,900,000 | 6.50% | Shares |
| FCPM III SERVICES B.V. | $30,201,336 | 1,677,852 | 5.74% | Shares |
| Balyasny Asset Management L.P. | $29,932,506 | 1,662,917 | 5.69% | Shares |
| Vestal Point Capital, LP | $29,340,000 | 1,630,000 | 5.58% | Shares |
| Opaleye Management Inc. | $23,748,318 | 1,319,351 | 4.51% | Shares |
| BlackRock, Inc. | $22,891,716 | 1,271,762 | 4.35% | Shares |
| TANG CAPITAL MANAGEMENT LLC | $20,880,000 | 1,160,000 | 3.97% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $13,819,590 | 767,755 | 2.63% | Shares |
| MILLENNIUM MANAGEMENT LLC | $7,269,462 | 403,859 | 1.38% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $6,923,843 | 384,576 | 1.32% | Shares |
| JENNISON ASSOCIATES LLC | $6,813,126 | 378,507 | 1.30% | Shares |
| RTW INVESTMENTS, LP | $6,711,408 | 372,856 | 1.28% | Shares |
| NEXTBio Capital Management LP | $6,711,408 | 372,856 | 1.28% | Shares |
| VANGUARD GROUP INC | $6,612,021 | 557,506 | 1.26% | Shares |
| Remedium Capital Partners, LLC | $6,502,500 | 361,250 | 1.24% | Shares |
| STATE STREET CORP | $5,680,566 | 315,587 | 1.08% | Shares |
| AMERIPRISE FINANCIAL INC | $5,446,224 | 302,568 | 1.04% | Shares |
| Point72 Asset Management, L.P. | $5,400,000 | 300,000 | 1.03% | Shares |
| MARSHALL WACE, LLP | $3,857,400 | 214,300 | 0.73% | Shares |
| PERCEPTIVE ADVISORS LLC | $3,724,956 | 206,942 | 0.71% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3,398,454 | 188,803 | 0.65% | Shares |
| TWO SIGMA INVESTMENTS, LP | $3,363,732 | 186,874 | 0.64% | Shares |
| STEMPOINT CAPITAL LP | $3,282,876 | 182,382 | 0.62% | Shares |
| UBS Group AG | $3,153,276 | 175,182 | 0.60% | Shares |
| NORTHERN TRUST CORP | $2,498,004 | 138,778 | 0.47% | Shares |
| Exome Asset Management LLC | $2,299,842 | 127,769 | 0.44% | Shares |
| SECTORAL ASSET MANAGEMENT INC | $2,183,400 | 121,300 | 0.42% | Shares |
| Woodline Partners LP | $1,700,784 | 94,488 | 0.32% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,354,050 | 75,225 | 0.26% | Shares |
| Burkehill Global Management, LP | $1,332,000 | 74,000 | 0.25% | Shares |
| Blackstone Inc. | $1,127,646 | 62,647 | 0.21% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1,063,872 | 59,104 | 0.20% | Shares |
| Y-Intercept (Hong Kong) Ltd | $914,832 | 50,824 | 0.17% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $904,644 | 50,258 | 0.17% | Shares |
| Nuveen, LLC | $857,322 | 47,629 | 0.16% | Shares |
| Bank of New York Mellon Corp | $824,004 | 45,778 | 0.16% | Shares |
| Stonepine Capital Management, LLC | $720,000 | 40,000 | 0.14% | Shares |
| BANK OF AMERICA CORP /DE/ | $464,778 | 25,821 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $458,766 | 25,487 | 0.09% | Shares |
| MOORE CAPITAL MANAGEMENT, LP | $450,000 | 25,000 | 0.09% | Shares |
| Squarepoint Ops LLC | $434,988 | 24,166 | 0.08% | Shares |
| AMERICAN CENTURY COMPANIES INC | $410,490 | 22,805 | 0.08% | Shares |
| TWO SIGMA ADVISERS, LP | $385,450 | 32,500 | 0.07% | Shares |
| WELLS FARGO & COMPANY/MN | $354,600 | 19,700 | 0.07% | Shares |
| ADAR1 Capital Management, LLC | $328,950 | 18,275 | 0.06% | Shares |
| Virtus Investment Advisers, LLC | $328,644 | 18,258 | 0.06% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $319,590 | 17,755 | 0.06% | Shares |
| MORGAN STANLEY | $318,564 | 17,698 | 0.06% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $262,800 | 14,600 | 0.05% | Shares |
| BANK OF MONTREAL /CAN/ | $247,824 | 13,768 | 0.05% | Shares |
| MetLife Investment Management, LLC | $230,040 | 12,780 | 0.04% | Shares |
| Invesco Ltd. | $211,158 | 11,731 | 0.04% | Shares |
| Persistent Asset Partners Ltd | $197,424 | 10,968 | 0.04% | Shares |
| XTX Topco Ltd | $190,152 | 10,564 | 0.04% | Shares |
| CITIGROUP INC | $182,538 | 10,141 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $178,218 | 9,901 | 0.03% | Shares |
| JPMORGAN CHASE & CO | $162,360 | 9,020 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $136,800 | 7,600 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $114,642 | 6,369 | 0.02% | Shares |
| BARCLAYS PLC | $80,316 | 4,462 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $59,454 | 3,303 | 0.01% | Shares |
| Vanguard Global Advisers, LLC | $48,852 | 2,714 | 0.01% | Shares |
| Legal & General Group Plc | $37,746 | 2,097 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $31,698 | 1,761 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $31,068 | 1,726 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $12,000 | 681 | 0.00% | Shares |
| US BANCORP \DE\ | $7,254 | 403 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5,346 | 297 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $4,961 | 275,581 | 0.00% | Shares |
| Parallel Advisors, LLC | $4,752 | 264 | 0.00% | Shares |
| Allworth Financial LP | $2,898 | 161 | 0.00% | Shares |
| Sterling Capital Management LLC | $1,368 | 76 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $1,224 | 68 | 0.00% | Shares |
| Fortitude Family Office, LLC | $720 | 40 | 0.00% | Shares |
| Quarry LP | $522 | 29 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $468 | 26 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $378 | 21 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $54 | 3 | 0.00% | Shares |