SECTORAL ASSET MANAGEMENT INC
CIK 1274413 · View on SEC EDGAR ↗
- Portfolio value
- $143.3M
- Positions
- 82
- As of
- June 30, 2026
#7,535 of 9,443 by 13F value · top 79.8%
Portfolio value QoQ: +18.7% 13F does not disclose cash
- Top 10 holdings weight
- 39.65%
- Top 25 holdings weight
- 67.66%
- Positions above 1%
- 35
- Effective number of positions
- 36.5
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q2 2026: 19.34% Est. buys $40,599,966 · sells $25,527,088
Median holding: 4.0 quarters Tracked Q4 2024–Q2 2026 · 56.2% still held
- New positions
- 15
- Increased
- 17
- Decreased
- 17
- Closed
- 10
On this page
- Performance vs S&P How this manager's 13F portfolio performed against the S&P 500.
- Sector breakdown How the portfolio splits across market sectors.
- Portfolio Every stock this institution reports holding, from its latest 13F.
- High-conviction bets The holdings this manager is most concentrated in.
- Biggest new bets Brand-new positions opened in the latest quarter.
- Top moves The biggest position increases and decreases this quarter.
- Exited positions Positions the manager fully sold out of last quarter.
Performance vs S&P 500
Annualized: +41.1% · S&P 500: +18.0%
Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.
Priceable coverage: 99.3% · Options excluded: 0.0%
Sector breakdown
Healthcare
96.5%
Other/Unmapped
3.5%
Full portfolio 82 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| CTNM Contineum Therapeutics, Inc. - Common stock | $11,925,151 | 8.32% | 727,587 | $2,422,865 | |||
| SI Shoulder Innovations, Inc. Common Stock | $8,728,654 | 6.09% | 430,407 | $2,474,840 | |||
| LLY Eli Lilly and Company Common Stock | $7,621,178 | 5.32% | 6,354 | $1,776,959 | |||
| UNH UnitedHealth Group Incorporated Common Stock (DE) | $5,500,863 | 3.84% | 13,235 | $1,453,648 | Down ×1 | ||
| JNJ Johnson & Johnson Common Stock | $4,626,825 | 3.23% | 18,218 | $173,617 | |||
| ORKA Oruka Therapeutics, Inc. - Common Stock | $3,995,903 | 2.79% | 41,987 | Up ×1 | |||
| BNTX BioNTech SE - American Depositary Shares | $3,895,910 | 2.72% | 41,869 | $1,850,603 | Up ×2 | ||
| DFTX Definium Therapeutics, Inc. - Common Shares | $3,683,702 | 2.57% | 78,310 | Up ×1 | |||
| DXCM DexCom, Inc. - Common Stock | $3,418,417 | 2.39% | 50,756 | $1,959,510 | Up ×1 | ||
| RCUS Arcus Biosciences, Inc. Common Stock | $3,418,122 | 2.39% | 110,870 | $2,382,618 | Up ×1 | ||
| AMGN Amgen Inc. - Common Stock | $3,335,125 | 2.33% | 9,210 | $-179,857 | |||
| SMMT Summit Therapeutics Inc. - Common Stock | $3,208,023 | 2.24% | 220,180 | $1,808,396 | Up ×1 | ||
| IRTC iRhythm Holdings, Inc. - Common Stock | $3,101,027 | 2.16% | 26,070 | Up ×1 | |||
| ABBV AbbVie Inc. Common Stock | $3,070,008 | 2.14% | 12,200 | $416,630 | |||
| MRK Merck & Company, Inc. Common Stock (new) | $2,772,981 | 1.94% | 21,480 | $189,152 | |||
| AVBP ArriVent BioPharma, Inc. - Common Stock | $2,745,954 | 1.92% | 79,043 | $2,025,524 | Up ×1 | ||
| VRTX Vertex Pharmaceuticals Incorporated - Common Stock | $2,698,237 | 1.88% | 5,432 | $-758,876 | Down ×2 | ||
| ARGX argenx SE - American Depositary Shares | $2,626,517 | 1.83% | 2,831 | $-110,460 | Down ×1 | ||
| GILD Gilead Sciences, Inc. - Common Stock | $2,605,131 | 1.82% | 20,620 | $-1,526,493 | Down ×1 | ||
| INSM Insmed Incorporated - Common Stock | $2,475,290 | 1.73% | 23,216 | $-905,486 | Up ×2 | ||
| TECX Tectonic Therapeutic, Inc. - Common Stock | $2,440,934 | 1.70% | 71,009 | $1,812,719 | Up ×1 | ||
| ISRG Intuitive Surgical, Inc. - Common Stock | $2,326,428 | 1.62% | 5,850 | $-93,770 | Up ×2 | ||
| IMTX Immatics N.V. - Ordinary Shares | $2,278,521 | 1.59% | 224,928 | $1,585,834 | Up ×2 | ||
| SYK Stryker Corporation Common Stock | $2,248,893 | 1.57% | 7,129 | $318,755 | Up ×1 | ||
| AVTX Avalo Therapeutics, Inc. - Common Stock | $2,216,177 | 1.55% | 119,923 | Up ×1 | |||
| CBIO Crescent Biopharma, Inc. - Common Stock | $2,183,400 | 1.52% | 121,300 | Up ×1 | |||
| ROIV Roivant Sciences Ltd. - Common Shares | $2,162,329 | 1.51% | 61,100 | $1,145,961 | Up ×1 | ||
| IQV IQVIA Holdings, Inc. Common Stock | $2,096,051 | 1.46% | 10,848 | $679,375 | Up ×1 | ||
| PLSE Pulse Biosciences, Inc - Common Stock | $1,882,728 | 1.31% | 67,895 | Up ×1 | |||
| DHR Danaher Corporation Common Stock | $1,830,726 | 1.28% | 9,597 | $11,135 | |||
| TMO Thermo Fisher Scientific Inc Common Stock | $1,759,926 | 1.23% | 3,508 | $35,639 | |||
| ABT Abbott Laboratories Common Stock | $1,640,579 | 1.14% | 18,080 | $-985,514 | Down ×1 | ||
| ATEC Alphatec Holdings, Inc. - Common Stock | $1,608,035 | 1.12% | 185,900 | Up ×1 | |||
| BSX Boston Scientific Corporation Common Stock | $1,550,564 | 1.08% | 36,330 | $-631,881 | Up ×4 | ||
| TMDX TransMedics Group, Inc. - Common Stock | $1,457,919 | 1.02% | 21,950 | Up ×1 | |||
| CYTK Cytokinetics, Incorporated - Common Stock | $1,391,153 | 0.97% | 16,330 | $846,539 | Up ×2 | ||
| REGN Regeneron Pharmaceuticals, Inc. - Common Stock | $1,352,458 | 0.94% | 2,169 | $-1,129,262 | Down ×3 | ||
| CVS CVS Health Corporation Common Stock | $1,344,850 | 0.94% | 13,000 | ||||
| EW Edwards Lifesciences Corporation Common Stock | $1,341,160 | 0.94% | 14,826 | $-47,267 | Down ×1 | ||
| TRVI Trevi Therapeutics, Inc. - Common Stock | $1,223,365 | 0.85% | 65,596 | $283,866 | Down ×4 | ||
| BMY Bristol-Myers Squibb Company Common Stock | $1,218,663 | 0.85% | 21,150 | $-64,085 | |||
| VERA Vera Therapeutics, Inc. - Class A Common Stock | $1,097,337 | 0.77% | 25,573 | $12,696 | |||
| COGT Cogent Biosciences, Inc. - Common Stock | $1,034,838 | 0.72% | 26,740 | $132,440 | Up ×1 | ||
| MDT Medtronic plc. Ordinary Shares | $876,345 | 0.61% | 11,100 | $-85,470 | |||
| TARS Tarsus Pharmaceuticals, Inc. - Common Stock | $836,158 | 0.58% | 13,285 | $-16,305 | Up ×1 | ||
| KURA Kura Oncology, Inc. - Common Stock | $784,136 | 0.55% | 71,480 | $178,126 | |||
| CNC Centene Corporation Common Stock | $770,280 | 0.54% | 12,000 | ||||
| UTHR United Therapeutics Corporation - Common Stock | $742,307 | 0.52% | 1,370 | $-403,330 | Down ×2 | ||
| HNGE Hinge Health, Inc. Class A Common Stock | $725,752 | 0.51% | 8,744 | $253,623 | Down ×2 | ||
| NKTR Nektar Therapeutics - Common Stock | $705,849 | 0.49% | 10,111 | $-114,813 | Down ×2 | ||
| ALNY Alnylam Pharmaceuticals, Inc. - Common Stock | $695,379 | 0.49% | 2,310 | $-168,853 | |||
| Unknown issuer (CUSIP: K08588103) | $685,470 | 0.48% | 2,570 | Up ×1 | |||
| PFE Pfizer, Inc. Common Stock | $662,200 | 0.46% | 27,500 | $-110,000 | |||
| ARDX Ardelyx, Inc. - Common Stock | $624,209 | 0.44% | 122,394 | $-156,851 | |||
| PRVA Privia Health Group, Inc. - Common Stock | $621,019 | 0.43% | 24,136 | $62,831 | Down ×1 | ||
| PTCT PTC Therapeutics, Inc. - Common Stock | $609,328 | 0.43% | 7,470 | $94,265 | Up ×1 | ||
| IONS Ionis Pharmaceuticals, Inc. - Common Stock | $570,888 | 0.40% | 7,200 | $-46,352 | |||
| AGMB AgomAb Therapeutics NV - ADRs representing one common share. | $564,630 | 0.39% | 43,500 | $87,335 | |||
| BMRN BioMarin Pharmaceutical Inc. - Common Stock | $540,729 | 0.38% | 9,450 | $-66,539 | |||
| ONC BeOne Medicines Ltd. - American Depositary Shares | $532,894 | 0.37% | 1,870 | $-98,167 | |||
| HUM Humana Inc. Common Stock | $497,299 | 0.35% | 1,250 | ||||
| JAZZ Jazz Pharmaceuticals plc - Ordinary Shares | $421,698 | 0.29% | 1,750 | $50,404 | |||
| RPRX Royalty Pharma plc - Class A Ordinary Shares | $403,704 | 0.28% | 7,200 | $9,870 | |||
| BIIB Biogen Inc. - Common Stock | $399,711 | 0.28% | 1,850 | $13,801 | |||
| MLYS Mineralys Therapeutics, Inc. - Common Stock | $392,964 | 0.27% | 14,565 | $-502,171 | Down ×4 | ||
| ILMN Illumina, Inc. - Common Stock | $374,870 | 0.26% | 2,132 | $78,799 | |||
| AXSM Axsome Therapeutics, Inc. - Common Stock | $367,155 | 0.26% | 1,500 | $77,286 | |||
| SNDX Syndax Pharmaceuticals, Inc. - Common Stock | $342,765 | 0.24% | 15,680 | $-444,701 | Down ×3 | ||
| RVMD Revolution Medicines, Inc. - Common Stock | $342,722 | 0.24% | 1,830 | $140,442 | |||
| ABVX Abivax SA - American Depositary Shares | $311,828 | 0.22% | 2,340 | $13,967 | |||
| BBIO BridgeBio Pharma, Inc. - Common Stock | $305,368 | 0.21% | 4,100 | $-381,908 | Down ×4 | ||
| MRNA Moderna, Inc. - Common Stock | $304,631 | 0.21% | 4,350 | $56,727 | |||
| GH Guardant Health, Inc. - Common Stock | $297,059 | 0.21% | 1,980 | $91,536 | |||
| INCY Incyte Corporation - Common Stock | $266,396 | 0.19% | 2,350 | $12,272 | |||
| ORIC Oric Pharmaceuticals, Inc. - Common Stock | $254,505 | 0.18% | 23,500 | $-78,146 | |||
| SPRY ARS Pharmaceuticals, Inc. - Common Stock | $239,499 | 0.17% | 29,900 | $-437,173 | Down ×1 | ||
| GPCR Structure Therapeutics Inc. - American Depositary Shares | $232,123 | 0.16% | 4,325 | $-478,682 | Down ×3 | ||
| MEDP Medpace Holdings, Inc. - Common Stock | $227,724 | 0.16% | 430 | $-366 | |||
| TEM Tempus AI, Inc. - Class A Common Stock | $224,768 | 0.16% | 3,880 | ||||
| CRBP Corbus Pharmaceuticals Holdings, Inc. - Common Stock | $187,600 | 0.13% | 20,000 | Up ×1 | |||
| PALI Palisade Bio, Inc. - Common Stock | $183,920 | 0.13% | 88,000 | $11,545 | |||
| Unknown issuer (CUSIP: 29286X101) | $37,541 | 0.03% | 21,700 | Up ×1 | |||
| No matches | |||||||
Conviction holdings
Positions increased for 3+ consecutive quarters.
Share counts are as reported in 13F filings (not split-adjusted)
| Security | Value | % of portfolio | Streak |
|---|---|---|---|
| BSX | $1,550,564 | 1.08% | up ×4 |
Biggest new bets
New positions opened this quarter, largest first.
| Security | Value | Shares | % of portfolio |
|---|---|---|---|
| ORKA | $3,995,903 | 41,987 | 2.79% |
| DFTX | $3,683,702 | 78,310 | 2.57% |
| IRTC | $3,101,027 | 26,070 | 2.16% |
| AVTX | $2,216,177 | 119,923 | 1.55% |
| CBIO | $2,183,400 | 121,300 | 1.52% |
| PLSE | $1,882,728 | 67,895 | 1.31% |
| ATEC | $1,608,035 | 185,900 | 1.12% |
| TMDX | $1,457,919 | 21,950 | 1.02% |
| CVS | $1,344,850 | 13,000 | 0.94% |
| CNC | $770,280 | 12,000 | 0.54% |
| Unknown issuer (CUSIP: K08588103) | $685,470 | 2,570 | 0.48% |
| HUM | $497,299 | 1,250 | 0.35% |
| TEM | $224,768 | 3,880 | 0.16% |
| CRBP | $187,600 | 20,000 | 0.13% |
| Unknown issuer (CUSIP: 29286X101) | $37,541 | 21,700 | 0.03% |
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| SI | Price move only | +0 | +$2.5M |
| CTNM | Price move only | +0 | +$2.4M |
| RCUS | Bought more | +66K | +$2.4M |
| AVBP | Bought more | +49K | +$2.0M |
| DXCM | Bought more | +28K | +$2.0M |
| BNTX | Bought more | +20K | +$1.9M |
| TECX | Bought more | +52K | +$1.8M |
| SMMT | Bought more | +151K | +$1.8M |
| LLY | Price move only | +0 | +$1.8M |
| IMTX | Bought more | +158K | +$1.6M |
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| LENZ | Sept. 30, 2025 | 977,245 | $28,643,051 | -89.7% |
| EVMN | June 30, 2026 | 589,005 | $13,541,225 | 5.6% |
| ANAB | Dec. 31, 2025 | 194,485 | $5,955,131 | 18.5% |
| BCAX | Dec. 31, 2025 | 266,495 | $4,207,956 | 45.6% |
| SLDB | Dec. 31, 2025 | 633,052 | $3,905,931 | 67.0% |
| MBX | Dec. 31, 2025 | 194,898 | $3,410,715 | 110.3% |
| XBI | Dec. 31, 2025 | 34,000 | $3,406,800 | No longer tracked |
| ZBIO | Dec. 31, 2025 | 152,025 | $3,374,955 | -12.1% |
| PVLA | Dec. 31, 2025 | 49,115 | $3,079,019 | 38.4% |
| TIL | Dec. 31, 2025 | 161,380 | $2,882,247 | -31.8% |
| REPL | Sept. 30, 2025 | 231,650 | $2,152,029 | 249.0% |
| MDT | June 30, 2025 | 23,850 | $2,143,161 | 5.7% |
| TRML | Sept. 30, 2025 | 116,510 | $1,862,995 | No longer tracked |
| AZN | March 31, 2026 | 15,232 | $1,400,277 | -16.1% |
| SRPT | March 31, 2025 | 11,020 | $1,339,922 | -69.4% |
| THC | June 30, 2025 | 9,000 | $1,210,500 | 56.0% |
| HCAT | March 31, 2025 | 160,000 | $1,131,200 | -64.8% |
| SWTX | June 30, 2025 | 25,325 | $1,117,592 | No longer tracked |
| MRUS | Dec. 31, 2025 | 11,545 | $1,086,962 | No longer tracked |
| PRVA | March 31, 2025 | 52,000 | $1,016,600 | -5.5% |
| BPMC | June 30, 2025 | 11,235 | $994,410 | No longer tracked |
| CVS | March 31, 2025 | 22,000 | $987,580 | 38.1% |
| VTYX | March 31, 2026 | 96,945 | $875,413 | No longer tracked |
| PHR | June 30, 2025 | 34,000 | $869,040 | -58.2% |
| RAPP | June 30, 2026 | 25,421 | $835,005 | 15.5% |
| GMED | Sept. 30, 2025 | 13,500 | $796,770 | 48.9% |
| NARI | March 31, 2025 | 15,153 | $773,561 | No longer tracked |
| BOLD | June 30, 2026 | 678,574 | $746,431 | 19.2% |
| ASND | June 30, 2026 | 2,800 | $728,276 | -3.3% |
| ICLR | June 30, 2025 | 4,000 | $699,960 | 18.7% |
| LEGN | Sept. 30, 2025 | 19,627 | $696,562 | -33.2% |
| LENZ | March 31, 2026 | 42,500 | $680,000 | -47.8% |
| CNC | Sept. 30, 2025 | 12,500 | $678,500 | 79.8% |
| CLOV | June 30, 2025 | 183,000 | $656,970 | 47.0% |
| ELV | June 30, 2025 | 1,500 | $652,440 | 2.8% |
| CI | March 31, 2025 | 2,250 | $621,315 | -15.9% |
| FOLD | March 31, 2026 | 43,300 | $616,592 | No longer tracked |
| IOVA | March 31, 2025 | 81,500 | $603,100 | 169.8% |
| CARL | March 31, 2026 | 47,700 | $589,095 | 78.1% |
| EW | March 31, 2025 | 7,850 | $581,136 | 23.3% |
| KMTS | Sept. 30, 2025 | 35,000 | $580,300 | 14.6% |
| CI | Dec. 31, 2025 | 1,800 | $518,850 | 0.6% |
| QURE | June 30, 2026 | 29,245 | $499,411 | 7.3% |
| BMY | Dec. 31, 2025 | 10,800 | $487,080 | 22.5% |
| ALHC | June 30, 2026 | 26,911 | $474,172 | -45.0% |
| COGT | June 30, 2025 | 79,020 | $473,330 | 403.5% |
| RDNT | June 30, 2026 | 7,999 | $447,064 | 23.5% |
| CVRX | Sept. 30, 2025 | 73,500 | $432,180 | -63.8% |
| ZLAB | Dec. 31, 2025 | 12,590 | $426,675 | 47.4% |
| ITCI | March 31, 2025 | 4,900 | $409,248 | No longer tracked |
| HUM | March 31, 2025 | 1,581 | $401,116 | 45.1% |
| INSP | June 30, 2026 | 7,225 | $372,666 | 36.1% |
| SRRK | Sept. 30, 2025 | 10,380 | $367,660 | 48.0% |
| SGOV | June 30, 2025 | 3,589 | $361,323 | -0.1% |
| OLMA | March 31, 2025 | 61,650 | $359,420 | 197.3% |
| NBIX | June 30, 2026 | 2,300 | $343,841 | -8.6% |
| OMDA | June 30, 2026 | 25,620 | $322,043 | 7.7% |
| RCKT | June 30, 2025 | 44,383 | $296,035 | 44.1% |
| TEM | March 31, 2026 | 4,500 | $265,725 | 46.8% |
| TSBX | March 31, 2025 | 517,648 | $257,219 | No longer tracked |
| RVMD | Sept. 30, 2025 | 6,240 | $229,570 | 354.7% |
| GERN | March 31, 2025 | 63,500 | $224,790 | -2.2% |
| CAI | Sept. 30, 2025 | 8,350 | $223,112 | -17.6% |
| MDGL | March 31, 2026 | 352 | $204,984 | -0.9% |
| NVO | June 30, 2025 | 2,850 | $197,904 | -32.3% |
| CRNX | June 30, 2025 | 5,710 | $191,513 | 194.7% |
| VTRS | Sept. 30, 2025 | 19,800 | $176,814 | 62.2% |
| MEDP | Sept. 30, 2025 | 531 | $166,660 | 18.5% |
| IOBT | Sept. 30, 2025 | 117,691 | $163,590 | No longer tracked |
| PCVX | Dec. 31, 2025 | 4,205 | $151,464 | 35.0% |
| CRSP | Sept. 30, 2025 | 2,540 | $123,546 | -8.1% |
| CRGX | March 31, 2025 | 8,500 | $122,570 | No longer tracked |
| EXEL | March 31, 2025 | 3,500 | $116,550 | 46.0% |
| ARVN | June 30, 2025 | 12,930 | $90,769 | 24.0% |
| RXRX | Sept. 30, 2025 | 11,500 | $58,190 | -30.4% |
| ENGN | June 30, 2025 | 11,700 | $52,416 | -50.7% |
| MLTX | Dec. 31, 2025 | 956 | $6,855 | 20.3% |