your badges 52W Range $19–$116 68% of range Analyst Rating BUY 20 analysts Price Target $155 +83% upside P/E -9.1 ROE -25.9% Net Profit Margin ·

ORKA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $84.52
Market Cap (MRQ) $5.16B
P/E -9.1
EPS $-3.87
Revenue $0
ROE -25.9%
52W Range $19–$116

ORKA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

Stock splits 6
Ex-date Split Type
Sept. 3, 2024 1-for-12 Reverse
April 4, 2019 1-for-18 Reverse
Sept. 4, 2015 1-for-7 Reverse
March 5, 2013 1-for-6 Reverse
Jan. 28, 2009 1-for-20 Reverse
Feb. 23, 2004 1-for-3 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$0
2017-12-31 → 2023-12-31
EPS$-3.87
2021-12-31 → 2024-12-31
Free Cash Flow$-88M
2017-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend ORKA 5Y avg Peer Median Verdict
P/E -9.15Y avg ≈-26.2 ≈-26.2 · ·
P/B (MRQ) 4.65Y avg ≈5.7 ≈5.7 9.3 Undervalued
Price / FCF (TTM) -51.05Y avg ≈-31.4 ≈-31.4 · ·
Price / Cash Flow (TTM) -51.15Y avg ≈-31.5 ≈-31.5 · ·
Price / Tangible Book 8.75Y avg ≈5.7 ≈5.7 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

13
Ex-dateAmountCurrencyYield
Aug 29, 2024$19.36USD≈64.5%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 12.9%
Next Report Nov 10, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 17, 2026 $-0.55 $-0.53 -4.6%
March 31, 2026 May 20, 2026 $-0.48 $-0.56 14.3%
Dec. 31, 2025 $-0.45 $-0.64 29.7%
Sept. 30, 2025 $-0.55 $-0.59 7.3%
June 30, 2025 $-0.46 $-0.50 8.0%
March 31, 2025 $-0.40 $-0.52 22.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 20252024202320222021202020192018201720162015
Revenue ··$0$0$0$0$0$0$0$0$0
R&D Expense $101M$75M$1M$5M$14M$5M$2M$4M$14M$12M$7M
SG&A Expense $21M$13M$6M$6M$6M$5M$4M$4M$5M$4M$4M
Operating Expenses $122M$88M$7M$11M$19M$10M$6M$8M$19M$17M$11M
Operating Income $-122M$-88M$-7M$-11M$-19M$-10M$-6M$-8M$-19M$-17M$-11M
Interest Expense ·····$9.0K$7.0K$8.0K$6.0K·$4.0K
Interest Income $17M$6M·········
Other Non-op $-12.0K$4.0K·········
Pretax Income $-105M$-84M··$-19M$-10M$-6M$-8M$-19M$-16M·
Income Tax ··$0$0$0$-9.0K$-167.0K$-31.0K$-61.0K$0$0
Net Income $-105M$-84M$-5M$-10M$-19M$-10M$-5M$-8M$-18M$-16M$-11M
EPS (Basic) ·$-3.87$-0.37$-0.69$-1.39······
EPS (Diluted) ·$-3.87$-0.37$-0.69$-1.39······
Shares (Basic) ·16,789,36214,415,87714,410,14313,903,871······
Shares (Diluted) ·16,789,36214,415,87714,410,14313,903,871······
EBITDA $-122M$-88M$-7M$-11M$-19M$-10M$-6M$-8M$-19M$-17M$-11M
Balance Sheet 21
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents $47M$62M$37M$42M$53M$49M$8M$7M$9M$7M$39M
Short-term Investments $290M$314M·········
Prepaid Expense $7M$1M·········
Other Current Assets ··$161.0K$254.0K$1M$897.0K$117.0K$169.0K$547.0K$282.0K$114.0K
Current Assets $344M$377M$38M$43M$54M$50M$8M$7M$12M$21M$39M
PP&E (Net) $288.0K$162.0K$10.0K$25.0K$48.0K$21.0K$10.0K$24.0K$42.0K$66.0K$28.0K
PP&E (Gross) ··$222.0K$229.0K$243.0K$271.0K$377.0K$398.0K$443.0K$453.0K$415.0K
Accum. Depreciation ··$212.0K$204.0K$195.0K$250.0K$367.0K$374.0K$401.0K$387.0K$387.0K
Other Non-current Assets $103.0K$43.0K$12.0K$18.0K$18.0K$12.0K$24.0K$24.0K$24.0K$766.0K$630.0K
Total Assets $489M$396M$38M$43M$55M$50M$9M$7M$12M$25M$40M
Accounts Payable ··$362.0K$334.0K$1M$2M$418.0K$230.0K$622.0K$1M$364.0K
Current Liabilities $15M$13M$637.0K$1M$3M$3M$926.0K$793.0K$2M$2M$2M
Capital Leases $1M$755.0K$204.0K$280.0K$383.0K$409.0K·····
Total Liabilities $17M$14M$841.0K$1M$4M$4M$926.0K$793.0K$2M$2M$2M
Common Stock $49.0K$37.0K$14.0K$14.0K$14.0K$10.0K$2.0K$1.0K$12.0K$9.0K$9.0K
Paid-in Capital $658M$463M·········
Retained Earnings $-189M$-84M$-189M$-183M$-173M$-154M$-144M$-139M$-131M$-113M$-96M
AOCI $546.0K$-41.0K······$-2.0K$-19.0K·
Stockholders' Equity $472M$382M$37M$42M$51M$47M$8M$6M$10M$22M$38M
Liabilities + Equity $489M$396M$38M$43M$55M$50M$9M$7M$12M$25M$40M
Shares Outstanding 48,722,30937,440,51014,501,14314,410,14314,410,1439,548,1501,594,070773,558654,1709,082,3669,051,217
Cash Flow 11
Metric Trend 20252024202320222021202020192018201720162015
D&A ··$15.0K$20.0K$16.0K$8.0K$18.0K$22.0K$27.0K$24.0K$19.0K
Stock-based Comp $24M$15M$686.0K$556.0K$497.0K$43.0K$151.0K$273.0K$458.0K$576.0K$599.0K
Operating Cash Flow $-88M$-58M$-5M$-11M$-19M$-8M$-5M$-8M$-17M$-15M$-11M
CapEx $209.0K$189.0K$0$2.0K$43.0K$19.0K$4.0K$4.0K$3.0K$12.0K$11.0K
Investing Cash Flow $-97M$-330M$0$-2.0K$-43.0K$-19.0K$-4.0K$3M$13M··
Stock Issued $671.0K$54.0K··$24M$51M$7M$4M$7M·$37M
Net Stock Activity $671.0K$54.0K··$24M$51M$7M$4M$7M·$37M
Financing Cash Flow $170M$450M$0$0$23M$48M$7M$3M$6M··
Net Change in Cash ··$-5M$-11M$4M$41M$2M$-2M$1M··
Free Cash Flow $-88M$-58M$-5M$-11M$-19M$-8M$-5M$-8M$-17M$-15M$-11M
Levered FCF ·····$-8M$-5M$-8M$-17M··
Profitability 3
Metric Trend 20252024202320222021202020192018201720162015
ROA -23.8%-42.3%-13.2%-20.3%-36.7%-33.0%-71.4%-82.7%-100.0%-51.2%-41.1%
ROE -25.9%-23.1%-14.2%-23.5%-35.9%-20.1%-66.8%-117.6%-150.2%-54.6%-43.3%
ROIC ·····-21.0%-74.1%-134.1%-181.5%··
Liquidity & Solvency 3
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 22.428.959.037.715.614.39.28.55.99.025.9
Quick Ratio 21.928.858.837.515.314.09.08.34.23.125.8
Interest Coverage ·····-1085.1-830.6-1014.8-3118.7·-2863.8
Efficiency 1
Metric Trend 20252024202320222021202020192018201720162015
Asset Turnover ··0.00.00.00.00.00.00.00.00.0
Per Share 5
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share $9.69$10.21$2.55$2.89$3.54$4.87$4.77$0.43$0.87$2.44$4.21
Revenue / Share ··$0.00$0.00·······
Cash Flow / Share ·$-3.44$-0.35$-0.76·······
Cash / Share $0.96$1.64$2.58$2.95$3.70$5.14$5.25$0.47$0.74$0.81$4.29
EPS (TTM) $-9.28$-3.87$-0.37$-0.69$-1.39······
Valuation (TTM) 9
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM ··$0$0$0$0$0$0$0$0$0
Net Income TTM $-105M$-84M$-5M$-10M$-19M$-10M$-5M$-8M$-18M$-16M$-11M
Market Cap $1.48B$726M$296M$410M$372M$459M$109M$993M$3.43B$5.59B$9.09B
P/E -3.3-5.0-55.1-41.2-18.6······
P/B 3.11.98.09.87.39.914.4164.5334.2251.9238.8
P / Tangible Book 3.11.98.09.87.39.9·····
P / Cash Flow -16.7-12.6-59.0-37.6-19.8-59.5-22.8-120.4-196.5-373.1-863.0
P / FCF -16.7-12.5-59.0-37.6-19.8-59.3-22.7-120.3-196.5-372.8-862.1
Earnings Yield -30.6%-20.0%-1.8%-2.4%-5.4%······

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312024-02-062023-12-312022-12-31
Revenue · · · $0 $0
Net Income $-105M $-84M · $-5M $-10M
Diluted EPS · $-3.87 · $-0.37 $-0.69

Institutional owners (13F) 263 filers · $6.8B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 263
Value held $6.8B
New positions 100
Exited positions 26
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
100 (+35 vs prior Q) 26 (+8 vs prior Q) 96 (+30 vs prior Q) 47 (+18 vs prior Q) +20.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $862,016,075 9,057,645 12.72% Shares
BlackRock, Inc. $474,915,526 4,990,181 7.01% Shares
Venrock Adviser, LLC $394,805,893 4,148,428 5.83% Shares
Fairmount Funds Management LLC $352,629,785 3,705,262 5.20% Shares
Capital World Investors $323,733,984 3,401,639 4.78% Shares
RTW INVESTMENTS, LP $298,741,485 3,139,030 4.41% Shares
STATE STREET CORP $254,384,117 2,673,090 3.75% Shares
VANGUARD CAPITAL MANAGEMENT LLC $224,693,610 2,360,971 3.32% Shares
Paradigm Biocapital Advisors LP $204,094,539 2,144,526 3.01% Shares
Deep Track Capital, LP $183,297,420 1,926,000 2.70% Shares
Bellevue Group AG $157,714,772 1,657,190 2.33% Shares
FRANKLIN RESOURCES INC $154,313,446 1,621,451 2.28% Shares
Remedium Capital Partners, LLC $149,003,957 1,565,661 2.20% Shares
RA CAPITAL MANAGEMENT, L.P. $147,950,996 1,554,597 2.18% Shares
VIKING GLOBAL INVESTORS LP $143,086,001 1,503,478 2.11% Shares
GEODE CAPITAL MANAGEMENT, LLC $136,113,846 1,429,954 2.01% Shares
PERCEPTIVE ADVISORS LLC $128,009,646 1,345,063 1.89% Shares
Polar Capital Holdings Plc $116,926,719 1,228,609 1.73% Shares
CITADEL ADVISORS LLC $106,496,277 1,119,011 1.57% Shares
BNP PARIBAS FINANCIAL MARKETS $102,689,858 1,079,015 1.52% Shares
VANGUARD GROUP INC $74,366,494 2,453,530 1.10% Shares
Avidity Partners Management LP $72,369,552 760,424 1.07% Shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC $62,650,506 658,301 0.92% Shares
Aberdeen Group plc $61,569,565 646,943 0.91% Shares
UBS Group AG $60,848,177 639,363 0.90% Shares
JPMORGAN CHASE & CO $60,736,334 655,027 0.90% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $60,093,479 631,433 0.89% Shares
Pictet Asset Management Holding SA $58,914,871 619,076 0.87% Shares
Affinity Asset Advisors, LLC $56,150,300 590,000 0.83% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $55,427,865 582,409 0.82% Shares
Cormorant Asset Management, LP $50,757,968 533,340 0.75% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $41,247,154 433,405 0.61% Shares
NORTHERN TRUST CORP $40,817,558 428,891 0.60% Shares
VOYA INVESTMENT MANAGEMENT LLC $38,177,350 401,149 0.56% Shares
VANGUARD FIDUCIARY TRUST CO $34,797,007 365,630 0.51% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $34,651,587 364,102 0.51% Shares
Synergy Asset Management, LLC $33,909,166 356,301 0.50% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $33,785,636 355,003 0.50% Shares
BANK OF AMERICA CORP /DE/ $33,578,260 352,824 0.50% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $33,576,166 352,802 0.50% Shares
Candriam S.C.A. $33,535,685 352,716 0.49% Shares
Holocene Advisors, LP $29,117,357 305,951 0.43% Shares
JENNISON ASSOCIATES LLC $28,480,289 299,257 0.42% Shares
Woodline Partners LP $27,146,957 285,247 0.40% Shares
BRAIDWELL LP $26,472,868 278,164 0.39% Shares
Siren, L.L.C. $23,792,500 250,000 0.35% Shares
Nuveen, LLC $23,722,741 249,267 0.35% Shares
EVENTIDE ASSET MANAGEMENT, LLC $22,840,800 240,000 0.34% Shares
Blackstone Inc. $22,565,568 237,108 0.33% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $20,846,000 219,039 0.31% Shares

Show all 263 institutional owners →

Activists & 5%+ owners 9 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Fairmount Funds Management LLC, Fairmount Healthcare Fund II L.P., Fairmount Healthcare Co-Invest III L.P., Harwin Peter Evan, Kiselak Tomas ×7 filings July 1, 2026 19.50% Amendment · SEC
Adage Capital Management, L.P., Robert Atchinson, Phillip Gross ×2 filings Oct. 22, 2024 · Initial filing · SEC
Funicular Funds, LP, The Funicular Fund, LP, Jacob Ma-Weaver July 8, 2022 · Initial filing · SEC
The Funicular Fund, LP, Jacob Ma-Weaver ×6 filings June 21, 2022 · Initial filing · SEC
March 5, 2018 · Initial filing · SEC
Growth Equity Opportunities Fund IV, LLC, New Enterprise Associates 15, L.P., NEA Partners 15, L.P., NEA 15 GP, LLC, Peter J. Barris, Forest Baskett, Anthony A. Florence, Jr., Krishna S. Kolluri, Joshua Makower, David M. Mott, Jon M. Sakoda, Scott D. Sandell, Peter W. Sonsini, Ravi Viswanathan, Harry R. Weller June 29, 2015 · Initial filing Passive investment SEC
Atlas Venture Fund VII, L.P., Atlas Venture Associates VII, L.P. Nov. 2, 2012 · Initial filing · SEC
Credit Suisse, on behalf of the Investment Banking division March 15, 2006 · Initial filing · SEC
Undisclosed reporting person April 6, 2004 · Initial filing Board campaign SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 61 insiders · 18 officers · 28 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Lawrence Otto Klein Chief Executive Officer Oct. 1, 2026 M 923,128 0 9 $-9,405,009
Jeffrey C. Dekker Chief Financial Officer Dec. 8, 2022 A 40,000 0 0 $0
Patrick M Wheeler Chief Financial Officer Sept. 18, 2014 S 101,510 0 0 $0
Kathryn E Falberg CFO and COO June 25, 2009 A 0 0 0 $0
Lee E Bendekgey Sr. VP CFO and General Counsel Feb. 1, 2008 A 6,511 0 0 $0
Henry Ward Wolff Sr. VP Finance and CFO Feb. 1, 2007 A 229 0 0 $0
Laura Lee Sandler Chief Operating Officer Sept. 15, 2026 S 235,478 0 19 $-1,942,513
Thomas A Keuer Chief Operating Officer Dec. 8, 2022 A 40,730 0 0 $0
Arjun Agarwal Senior Vice President, Finance Sept. 21, 2026 S 14,219 0 26 $-4,329,391
Paul T Quinlan General Counsel Sept. 21, 2026 M 29,995 0 13 $-6,758,520
Joana Goncalves Chief Medical Officer Sept. 15, 2026 M 31,771 0 35 $-4,543,414
Larry Todd Edwards Chief Commercial Officer Aug. 24, 2026 A 100,000 0 0 $0
Michael R Bristow Pres. & Chief Executive Offic Dec. 14, 2021 A 41,155 0 0 $0
Brian L. Selby VP, Finance Dec. 21, 2020 A 0 0 0 $0
Michael D Levy Executive Vice President Feb. 1, 2008 A 20,821 0 0 $0
Gary Titus Chief Acct.Officer Aug. 30, 2006 S 2,633 0 0 $0
Peter S Garcia Senior V.P. and C.F.O. May 7, 2004 A · 0 0 $0
Linda A Fitzpatrick Senior V.P. of Human Resources May 7, 2004 A · 0 0 $0
Carl Dambkowski Director June 12, 2026 S 38,743 0 5 $-8,645,640
Christopher Nathan Martin Director June 2, 2026 A · 0 0 $0
Samarth Kulkarni Director June 2, 2026 A · 0 0 $0
Kristine M Ball Director June 2, 2026 A · 0 0 $0
Cameron Turtle Director June 2, 2025 A · 0 0 $0
Flynn James P. Director Jan. 30, 2024 A · 0 0 $0
Raymond L. Woosley Director Jan. 30, 2024 A · 0 0 $0
Linda S Grais Director Jan. 30, 2024 A 491,889 0 0 $0
Anders D Hove Director Jan. 30, 2024 A · 0 0 $0
Robert E Conway Director Jan. 30, 2024 A 50,000 0 0 $0
Daniel J Mitchell Director Jan. 30, 2024 A 11,000 0 0 $0
ZABRISKIE JOHN L Director Sept. 17, 2013 A 156,131 0 0 $0
FORMELA JEAN FRANCOIS Director Oct. 22, 2012 A 1,579,542 0 0 $0
Burton E Sobel Director Feb. 10, 2012 A 0 0 0 $0
Richard B Brewer Director Feb. 10, 2012 A · 0 0 $0
William J Freytag Director Feb. 5, 2010 A · 0 0 $0
Mary K Pendergast Director Feb. 5, 2010 A 2,000 0 0 $0
Ted W Love Director Feb. 5, 2010 A 57,289 0 0 $0
David George Lowe Director July 21, 2009 S 129,600 0 0 $0
Kimberly J Popovits Director June 4, 2008 A · 0 0 $0
James R Gavin III Director June 4, 2008 A · 0 0 $0
Mark L Perry Director June 4, 2008 A 65,833 0 0 $0
Barry L Zubrow Director May 31, 2007 A 50,000 0 0 $0
George B Rathmann Director May 24, 2005 A 903,788 0 0 $0
Philippe Chambon Director May 6, 2004 A 5,759,875 0 0 $0
Carter Iii Thomas N Mc Director March 27, 2003 A · 0 0 $0
Funicular Funds, LP 10% owner July 1, 2022 J 2,580,452 0 0 $0
Jon Sakoda 10% owner Feb. 26, 2018 S 0 0 0 $0
Anthony A. Florence, Jr. 10% owner Feb. 26, 2018 S 0 0 0 $0
Peter W. Sonsini 10% owner Feb. 26, 2018 S 0 0 0 $0
Ravi Viswanathan 10% owner Feb. 26, 2018 S 0 0 0 $0
Forest Baskett 10% owner Feb. 26, 2018 S 0 0 0 $0
Scott D. Sandell 10% owner Feb. 26, 2018 S 0 0 0 $0
Joshua Makower 10% owner Feb. 26, 2018 S 0 0 0 $0
David M Mott 10% owner Feb. 26, 2018 S 0 0 0 $0
Peter J Barris 10% owner Feb. 26, 2018 S 0 0 0 $0
mccormack riley 10% owner Jan. 16, 2015 S 2,100,000 0 0 $0
Atlas Venture Fund VII L P 10% owner March 29, 2010 S 1,337,612 0 0 $0
Ma-Weaver Jacob · Aug. 29, 2024 J · 0 0 $0
Funicular Fund, LP · April 4, 2022 P 1,944,993 0 0 $0
Christopher David Ozeroff · Dec. 14, 2021 A 50,970 0 0 $0
Skyline Venture Partners Qualified Purchaser Fund IV L P · June 15, 2009 S 335,400 0 0 $0
CREDIT SUISSE/ · July 30, 2004 C 7,230 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 33 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
DWAS · Invesco Exchange-Traded Fund Trust … 1.24% 60,400 SH Oct. 2, 2026 Daily
LABU · Direxion Shares ETF Trust 1.03% 52,700 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.93% 4,447 NS July 31, 2026 N-PORT
JSML · Janus Detroit Street Trust 0.76% 28,596 NS July 31, 2026 N-PORT
JSMD · Janus Detroit Street Trust 0.75% 82,097 NS July 31, 2026 N-PORT
MEDI · Harbor ETF Trust 0.60% 2,546 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.37% 4,675 SH Oct. 2, 2026 Daily
IBB · iShares Trust 0.34% 387,461 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.30% 474,512 SH Sept. 11, 2026 Daily
PWS · Pacer Funds Trust 0.29% 720 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.28% 53,886 SH Aug. 19, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.21% 43,678 SH Aug. 19, 2026 Daily
BKSE · BNY Mellon ETF Trust 0.18% 1,613 NS July 31, 2026 N-PORT
FFSM · FIDELITY COVINGTON TRUST 0.17% 26,725 NS July 31, 2026 N-PORT
RSSL · Global X Funds 0.16% 24,116 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.15% 1,290,256 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.15% 289,905 SH Aug. 19, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.13% 9,664 NS July 31, 2026 N-PORT
ESML · iShares Trust 0.08% 23,234 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.05% 580,805 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.04% 14,937 NS July 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.04% 94,538 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.03% 2,436 SH Sept. 11, 2026 Daily
DFAS · Dimensional ETF Trust 0.03% 42,314 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 6,687 SH Oct. 2, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.01% 1,725,048 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 4,138 SH Aug. 19, 2026 Daily
ITOT · iShares Trust 0.01% 68,259 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.01% 13,545 SH Sept. 11, 2026 Daily
PTH · Invesco Exchange-Traded Fund Trust 0.00% 72 SH Oct. 2, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 1,553 NS July 31, 2026 N-PORT
ISCB · iShares Trust · 1,604 SH Sept. 11, 2026 Daily
SMMV · iShares Trust · 1,959 SH Sept. 1, 2026 Daily

ORKA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 20 analysts BUY
Median target $155.50 +84.0%
9 45.0% Strong Buy
10 50.0% Buy
1 5.0% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

12 analysts · 2026-09-28

Mean target $155.00 +83.4%

← Below all targets Current price $84.52
Low$117.00 Mean$155.00 High$200.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ORKA $1.48B -3.3 · · -25.9% ·
RYTM $7.19B -34.4 45.8% -103.6% -309.1% ·
GRAL $3.45B -7.7 17.2% -277.5% -16.7% ·
KOD $1.73B -6.5 · · -202.0% ·
CGON $3.35B -20.0 254.7% -3985.0% -22.6% ·
SRRK $4.78B -13.4 · · -157.9% ·
COGT $5.72B -16.4 · · -83.1% ·
MIRM $4.10B -168.1 54.7% -4.5% -8.2% ·
TVTX $3.47B -131.8 110.5% -5.2% -34.6% ·
PTCT $6.19B 9.8 114.5% 39.4% -331.5% ·
ERAS $1.06B -8.5 · · -35.7% ·

Latest News Recent headlines mentioning this company

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Leerink Partners Lifts PT on Oruka Therapeutics, Inc. (ORKA) Yahoo Finance · 4 months, 3 weeks ago VR Adviser Adds Over 1 Million Savara Shares Yahoo Finance · 6 months, 2 weeks ago

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 10, 2026