| BVF INC/IL |
$24,795,531 |
6,293,282 |
12.81% |
주식
|
| BlackRock, Inc. |
$20,187,937 |
5,123,842 |
10.43% |
주식
|
| Defilade Capital Management, L.P. |
$13,889,832 |
3,525,338 |
7.18% |
주식
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$13,463,859 |
3,417,223 |
6.96% |
주식
|
| GOLDMAN SACHS GROUP INC |
$9,890,613 |
2,510,308 |
5.11% |
주식
|
| Ensign Peak Advisors, Inc |
$8,278,823 |
2,101,224 |
4.28% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$7,710,867 |
1,956,601 |
3.98% |
주식
|
| Catalio Capital Management, LP |
$6,678,580 |
1,695,071 |
3.45% |
주식
|
| STATE STREET CORP |
$6,390,558 |
1,621,969 |
3.30% |
주식
|
| Zimmer Partners, LP |
$6,290,600 |
1,596,599 |
3.25% |
주식
|
| VANGUARD GROUP INC |
$6,099,926 |
4,039,686 |
3.15% |
주식
|
| SPHERA FUNDS MANAGEMENT LTD. |
$4,693,277 |
1,191,187 |
2.42% |
주식
|
| AWM Investment Company, Inc. |
$4,334,000 |
1,100,000 |
2.24% |
주식
|
| UBS Group AG |
$4,130,085 |
1,048,245 |
2.13% |
주식
|
| KINGDON CAPITAL MANAGEMENT, L.L.C. |
$4,094,744 |
1,039,275 |
2.12% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$3,860,065 |
979,712 |
1.99% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$3,479,402 |
883,097 |
1.80% |
주식
|
| ADAR1 Capital Management, LLC |
$2,552,379 |
647,812 |
1.32% |
주식
|
| 22NW, LP |
$2,507,274 |
636,364 |
1.30% |
주식
|
| NORTHERN TRUST CORP |
$2,428,612 |
616,399 |
1.25% |
주식
|
| AQR CAPITAL MANAGEMENT LLC |
$2,289,251 |
581,028 |
1.18% |
주식
|
| CM Management, LLC |
$2,265,500 |
575,000 |
1.17% |
주식
|
| Blue Owl Capital Holdings LP |
$2,232,045 |
566,509 |
1.15% |
주식
|
| DIMENSIONAL FUND ADVISORS LP |
$2,122,256 |
538,738 |
1.10% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2,101,458 |
533,365 |
1.09% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$2,084,114 |
528,963 |
1.08% |
주식
|
| MORGAN STANLEY |
$1,911,262 |
485,092 |
0.99% |
주식
|
| Triumph Capital Management |
$1,195,565 |
303,443 |
0.62% |
주식
|
| Brevan Howard Capital Management LP |
$1,174,645 |
304,707 |
0.61% |
주식
|
| CITADEL ADVISORS LLC |
$1,100,836 |
279,400 |
0.57% |
풋 옵션
|
| JANE STREET GROUP, LLC |
$1,095,320 |
278,000 |
0.57% |
풋 옵션
|
| BIT Capital GmbH |
$1,048,040 |
266,000 |
0.54% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$993,794 |
252,232 |
0.51% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$978,302 |
248,300 |
0.51% |
풋 옵션
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$974,772 |
247,404 |
0.50% |
주식
|
| CITADEL ADVISORS LLC |
$850,934 |
215,973 |
0.44% |
주식
|
| Nuveen, LLC |
$823,842 |
209,097 |
0.43% |
주식
|
| RENAISSANCE TECHNOLOGIES LLC |
$791,546 |
200,900 |
0.41% |
주식
|
| Bank of New York Mellon Corp |
$657,690 |
166,927 |
0.34% |
주식
|
| LPL Financial LLC |
$440,078 |
111,695 |
0.23% |
주식
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$432,774 |
109,841 |
0.22% |
주식
|
| Maven Securities LTD |
$394,000 |
100,000 |
0.20% |
주식
|
| RHUMBLINE ADVISERS |
$349,112 |
88,609 |
0.18% |
주식
|
| SIMPLEX TRADING, LLC |
$349,072 |
88,597 |
0.18% |
주식
|
| Prodigy Asset Management LLC |
$341,610 |
86,703 |
0.18% |
주식
|
| Daytona Street Capital LLC |
$313,301 |
81,166 |
0.16% |
주식
|
| DEUTSCHE BANK AG\ |
$301,973 |
76,643 |
0.16% |
주식
|
| WELLS FARGO & COMPANY/MN |
$295,280 |
74,944 |
0.15% |
주식
|
| Rockefeller Capital Management L.P. |
$286,304 |
72,666 |
0.15% |
주식
|
| Susquehanna Portfolio Strategies, LLC |
$283,361 |
71,919 |
0.15% |
주식
|
| Shay Capital LLC |
$252,160 |
64,000 |
0.13% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$236,006 |
59,900 |
0.12% |
콜 옵션
|
| Invesco Ltd. |
$233,630 |
59,297 |
0.12% |
주식
|
| PW Nova Financial Services LLC |
$228,682 |
58,041 |
0.12% |
주식
|
| WELLINGTON MANAGEMENT GROUP LLP |
$200,983 |
51,011 |
0.10% |
주식
|
| Mariner, LLC |
$197,149 |
50,041 |
0.10% |
주식
|
| IEQ CAPITAL, LLC |
$189,770 |
48,165 |
0.10% |
주식
|
| WOLVERINE TRADING, LLC |
$179,324 |
70,600 |
0.09% |
풋 옵션
|
| Russell Investments Group, Ltd. |
$161,237 |
40,923 |
0.08% |
주식
|
| MetLife Investment Management, LLC |
$161,217 |
40,918 |
0.08% |
주식
|
| Kera Capital Partners, Inc. |
$158,420 |
40,208 |
0.08% |
주식
|
| WOLVERINE TRADING, LLC |
$151,318 |
59,574 |
0.08% |
주식
|
| XTX Topco Ltd |
$150,930 |
38,307 |
0.08% |
주식
|
| CITIGROUP INC |
$142,147 |
36,078 |
0.07% |
주식
|
| NAVELLIER & ASSOCIATES INC |
$141,545 |
35,925 |
0.07% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$139,764 |
35,473 |
0.07% |
주식
|
| RAYMOND JAMES FINANCIAL INC |
$139,527 |
35,413 |
0.07% |
주식
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$133,268 |
34,615 |
0.07% |
주식
|
| MERCER GLOBAL ADVISORS INC /ADV |
$131,986 |
33,499 |
0.07% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$129,803 |
32,945 |
0.07% |
주식
|
| JPMORGAN CHASE & CO |
$125,367 |
32,311 |
0.06% |
주식
|
| MARCO INVESTMENT MANAGEMENT LLC |
$119,555 |
30,344 |
0.06% |
주식
|
| Retirement Planning Group, LLC |
$118,204 |
30,001 |
0.06% |
주식
|
| HOWARD FINANCIAL SERVICES, LTD. |
$118,200 |
30,000 |
0.06% |
주식
|
| Cetera Investment Advisers |
$113,736 |
28,867 |
0.06% |
주식
|
| KESTRA PRIVATE WEALTH SERVICES, LLC |
$108,350 |
27,500 |
0.06% |
주식
|
| SEI INVESTMENTS CO |
$106,857 |
27,121 |
0.06% |
주식
|
| Cerity Partners LLC |
$104,793 |
26,597 |
0.05% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$99,792 |
32,400 |
0.05% |
주식
|
| Vanguard Global Advisers, LLC |
$98,248 |
24,936 |
0.05% |
주식
|
| GROUP ONE TRADING LLC |
$97,416 |
24,725 |
0.05% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$92,622 |
23,508 |
0.05% |
주식
|
| Creative Planning |
$92,428 |
23,459 |
0.05% |
주식
|
| Scientech Research LLC |
$90,005 |
22,844 |
0.05% |
주식
|
| JANE STREET GROUP, LLC |
$88,173 |
22,379 |
0.05% |
주식
|
| Private Advisor Group, LLC |
$85,735 |
21,760 |
0.04% |
주식
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$84,517 |
21,451 |
0.04% |
주식
|
| Jump Financial, LLC |
$83,847 |
21,281 |
0.04% |
주식
|
| INTECH INVESTMENT MANAGEMENT LLC |
$76,570 |
19,434 |
0.04% |
주식
|
| JONES FINANCIAL COMPANIES LLLP |
$75,419 |
19,952 |
0.04% |
주식
|
| Relyea Zuckerberg Hanson LLC |
$66,980 |
17,000 |
0.03% |
주식
|
| COMMONWEALTH EQUITY SERVICES, LLC |
$65,230 |
16,556 |
0.03% |
주식
|
| Baker Ellis Asset Management LLC |
$63,040 |
16,000 |
0.03% |
주식
|
| China Universal Asset Management Co., Ltd. |
$63,040 |
16,000 |
0.03% |
주식
|
| VOYA INVESTMENT MANAGEMENT LLC |
$62,670 |
15,906 |
0.03% |
주식
|
| CITADEL ADVISORS LLC |
$60,282 |
15,300 |
0.03% |
콜 옵션
|
| BLAIR WILLIAM & CO/IL |
$58,875 |
14,943 |
0.03% |
주식
|
| JANE STREET GROUP, LLC |
$57,524 |
14,600 |
0.03% |
콜 옵션
|
| Independent Advisor Alliance |
$56,342 |
14,300 |
0.03% |
주식
|
| Revolve Wealth Partners, LLC |
$55,723 |
14,143 |
0.03% |
주식
|
| Waverly Advisors, LLC |
$54,577 |
13,852 |
0.03% |
주식
|
| CAPTRUST FINANCIAL ADVISORS |
$53,848 |
13,667 |
0.03% |
주식
|
| NEUBERGER BERMAN GROUP LLC |
$52,190 |
13,246 |
0.03% |
주식
|
| Tower Research Capital LLC (TRC) |
$51,039 |
12,954 |
0.03% |
주식
|
| SIGNATUREFD, LLC |
$50,964 |
12,935 |
0.03% |
주식
|
| WINTON GROUP Ltd |
$50,826 |
12,900 |
0.03% |
주식
|
| Universal- Beteiligungs- und Servicegesellschaft mbH |
$49,888 |
12,662 |
0.03% |
주식
|
| BARCLAYS PLC |
$46,843 |
11,889 |
0.02% |
주식
|
| PRUDENTIAL FINANCIAL INC |
$45,389 |
11,520 |
0.02% |
주식
|
| Summit Financial, LLC |
$45,310 |
11,500 |
0.02% |
주식
|
| GK Wealth Management LLC |
$45,259 |
11,487 |
0.02% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$44,100 |
11,193 |
0.02% |
주식
|
| Merit Financial Group, LLC |
$43,860 |
11,132 |
0.02% |
주식
|
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
$43,242 |
10,975 |
0.02% |
주식
|
| ProShare Advisors LLC |
$39,738 |
10,086 |
0.02% |
주식
|
| GRANDFIELD & DODD, LLC |
$39,400 |
10,000 |
0.02% |
주식
|
| Everhart Financial Group, Inc. |
$39,400 |
10,000 |
0.02% |
주식
|
| Ellis Investment Partners, LLC |
$39,400 |
10,000 |
0.02% |
주식
|
| Split Rock Private Trading & Wealth Management, LLC |
$39,400 |
10,000 |
0.02% |
주식
|
| Clarity Capital Partners LLC |
$31,165 |
11,500 |
0.02% |
주식
|
| CWM, LLC |
$30,628 |
9,944 |
0.02% |
주식
|
| OSAIC HOLDINGS, INC. |
$27,697 |
7,030 |
0.01% |
주식
|
| Legal & General Group Plc |
$27,580 |
7,000 |
0.01% |
주식
|
| Congress Wealth Management LLC / DE / |
$27,100 |
10,000 |
0.01% |
주식
|
| FARMERS & MERCHANTS INVESTMENTS INC |
$24,905 |
6,321 |
0.01% |
주식
|
| FMR LLC |
$24,566 |
6,235 |
0.01% |
주식
|
| ROYAL BANK OF CANADA |
$24,000 |
6,073 |
0.01% |
주식
|
| Ameritas Investment Partners, Inc. |
$23,577 |
5,984 |
0.01% |
주식
|
| Arax Advisory Partners |
$23,577 |
5,984 |
0.01% |
주식
|
| SOA Wealth Advisors, LLC. |
$17,990 |
4,566 |
0.01% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$16,548 |
4,200 |
0.01% |
주식
|
| FIFTH THIRD BANCORP |
$15,311 |
3,886 |
0.01% |
주식
|
| LANARK FINANCIAL, INC. |
$11,820 |
3,000 |
0.01% |
주식
|
| Federation des caisses Desjardins du Quebec |
$9,850 |
2,500 |
0.01% |
주식
|
| Costello Asset Management, INC |
$7,880 |
2,000 |
0.00% |
주식
|
| Allworth Financial LP |
$7,699 |
1,954 |
0.00% |
주식
|
| Steward Partners Investment Advisory, LLC |
$5,910 |
1,500 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$5,685 |
1,443 |
0.00% |
주식
|
| HARBOUR INVESTMENTS, INC. |
$5,548 |
1,408 |
0.00% |
주식
|
| NATIONAL BANK OF CANADA /FI/ |
$5,494 |
1,398 |
0.00% |
주식
|
| MassMutual Private Wealth & Trust, FSB |
$5,142 |
1,305 |
0.00% |
주식
|
| Sankala Group LLC |
$5,137 |
1,425 |
0.00% |
주식
|
| Anchor Investment Management, LLC |
$5,024 |
1,275 |
0.00% |
주식
|
| GAMMA Investing LLC |
$4,681 |
1,188 |
0.00% |
주식
|
| PNC Financial Services Group, Inc. |
$4,342 |
1,102 |
0.00% |
주식
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$4,125 |
1,047 |
0.00% |
주식
|
| Essential Partners LLC |
$4,094 |
1,039 |
0.00% |
주식
|
| Farther Finance Advisors, LLC |
$2,499 |
637 |
0.00% |
주식
|
| True Wealth Design, LLC |
$1,947 |
494 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$1,651 |
419 |
0.00% |
주식
|
| IMG Wealth Management, Inc. |
$1,387 |
352 |
0.00% |
주식
|
| St. Johns Investment Management Company, LLC |
$1,269 |
322 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$1,064 |
270 |
0.00% |
주식
|
| Quaker Wealth Management, LLC |
$753 |
191 |
0.00% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$520 |
132 |
0.00% |
주식
|
| Caitong International Asset Management Co., Ltd |
$426 |
108 |
0.00% |
주식
|
| Clearstead Advisors, LLC |
$363 |
92 |
0.00% |
주식
|
| SJS Investment Consulting Inc. |
$339 |
86 |
0.00% |
주식
|
| MCGUIRE CAPITAL ADVISORS INC |
$260 |
66 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$253 |
63,984 |
0.00% |
주식
|
| SBI Securities Co., Ltd. |
$248 |
63 |
0.00% |
주식
|
| Cambridge Investment Research Advisors, Inc. |
$236 |
59,945 |
0.00% |
주식
|
| Fortitude Family Office, LLC |
$232 |
59 |
0.00% |
주식
|
| INGALLS & SNYDER LLC |
$204 |
51,849 |
0.00% |
주식
|
| GSA CAPITAL PARTNERS LLP |
$166 |
42,028 |
0.00% |
주식
|
| Virtu Financial LLC |
$158 |
40,043 |
0.00% |
주식
|
| PITTENGER & ANDERSON INC |
$138 |
35 |
0.00% |
주식
|
| Sunbelt Securities, Inc. |
$80 |
26 |
0.00% |
주식
|
| JPL Wealth Management, LLC |
$44 |
11 |
0.00% |
주식
|
| IFP Advisors, Inc |
$32 |
8 |
0.00% |
주식
|
| Byrne Asset Management LLC |
$4 |
1 |
0.00% |
주식
|
| Navigoe, LLC |
$3 |
1,005 |
0.00% |
주식
|