ANRO Alto Neuroscience, Inc. Common Stock
$34.15
Price · Aug 18, 2026
Fundamentals as of Aug 12, 2026
52W Range
$3–$34
99% of range
Analyst Rating
STRONG BUY
16 analysts
Price Target
$38
+11% upside
P/E (TTM)
-17.1
ROE
-46.1%
Net Profit Margin
—
ANRO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$34.15
Market Cap
$1.20B
P/E (TTM)
-17.1
EPS (TTM)
$-2.19
Revenue (TTM)
—
Div Yield
—
ROE
-46.1%
Debt/Equity
0.1
52W Range
$3 – $34
ANRO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
—
EPS
$-2.19
2023-12-31
→
2025-12-31
Free Cash Flow
$-52M
2024-12-31
→
2025-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
ANRO
Peer Median
P/E (TTM)
-17.1
29.9
P/B
7.9
4.4
EV / EBITDA
-15.6
—
Price / FCF
-23.1
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
ANRO
Peer Median
ROA
-34.9%
-0.55%
ROE
-46.1%
-2.5%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
ANRO
Peer Median
Debt / Equity
0.1
—
Current Ratio
15.7
3.9
Quick Ratio
15.6
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
ANRO
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
ANRO
Peer Median
ANRO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
16 analysts
- Strong Buy 8 50.0%
- Buy 6 37.5%
- Hold 2 12.5%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
9 analysts · 2026-08-14
Median
$37.00
Now
$34.15
Low
$26.00
High
$50.00
Median target
$37.00
+8.3%
Mean target
$37.98
+11.2%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.02%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.80 | $-0.55 | -0.25% |
| Dec. 31, 2025 | $-0.58 | $-0.54 | -0.04% |
| Sept. 30, 2025 | $-0.52 | $-0.68 | 0.16% |
| June 30, 2025 | $-0.65 | $-0.63 | -0.02% |
| March 31, 2025 | $-0.56 | $-0.62 | 0.06% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| ANRO | $568M | -8.1 | — | — | -46.1% | — |
| HROW | $1.82B | -350.0 | 36.4% | -1.9% | -8.4% | 75.0% |
| XERS | $1.30B | — | 43.7% | 0.19% | -19.7% | — |
| PAHC | — | 21.5 | 27.4% | 3.7% | 17.8% | 30.9% |
| SPTX | — | — | — | — | — | — |
| EYPT | $1.51B | -5.8 | -27.5% | -739.4% | -84.0% | — |
| OMER | $1.23B | -343.6 | — | — | 1.9% | — |
| LXRX | $421M | -8.2 | 60.2% | -101.1% | -39.7% | — |
| LLY | — | 46.8 | 44.7% | 31.7% | 101.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 13
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| R&D Expense | $46M | $47M | $30M | |
| SG&A Expense | $21M | $22M | $8M | |
| Operating Expenses | $66M | $69M | $38M | |
| Operating Income | $-66M | $-69M | $-38M | |
| Interest Income | $7M | $9M | $2M | |
| Other Non-op | $3M | $7M | $2M | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-63M | $-61M | $-36M | |
| EPS (Basic) | $-2.19 | $-2.50 | $-9.73 | |
| EPS (Diluted) | $-2.19 | $-2.50 | $-9.73 | |
| Shares (Basic) | 28,852,000 | 24,602,000 | 3,731,000 | |
| Shares (Diluted) | 28,852,000 | 24,602,000 | 3,731,000 | |
| EBITDA | $-66M | $-68M | · |
Balance Sheet 20
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $176M | $168M | $83M | |
| Prepaid Expense | $1M | $1M | $3M | |
| Other Current Assets | · | $30.0K | $112.0K | |
| Current Assets | $178M | $169M | $85M | |
| PP&E (Net) | $2M | $3M | $1M | |
| Accum. Depreciation | $2M | $1M | $684.0K | |
| Total Assets | $185M | $178M | $87M | |
| Accounts Payable | $2M | $2M | $1M | |
| Accrued Liabilities | $9M | $8M | $5M | |
| Current Liabilities | $11M | $10M | $6M | |
| Capital Leases | $4M | $5M | $0 | |
| Total Liabilities | $34M | $26M | $17M | |
| Long-term Debt | $17M | $10M | $10M | |
| Total Debt | $17M | $10M | · | |
| Paid-in Capital | $353M | $290M | $5M | |
| Retained Earnings | $-202M | $-138M | $-77M | |
| AOCI | $22.0K | $-101.0K | $-79.0K | |
| Stockholders' Equity | $151M | $151M | $-72M | |
| Liabilities + Equity | $185M | $178M | $87M | |
| Shares Outstanding | 31,924,000 | 26,987,000 | 3,832,000 |
Cash Flow 10
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | · | $502.0K | $373.0K | |
| Stock-based Comp | $8M | $8M | $3M | |
| Other Non-cash | · | $6M | · | |
| Operating Cash Flow | $-52M | $-47M | $-33M | |
| CapEx | $24.0K | $2M | $470.0K | |
| Investing Cash Flow | $-24.0K | $-2M | $-470.0K | |
| Net Debt Issued | $-10M | · | · | |
| Financing Cash Flow | $60M | $136M | $68M | |
| Net Change in Cash | $8M | $86M | $34M | |
| Free Cash Flow | $-52M | $-49M | · |
Profitability 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| ROA | -34.9% | -46.5% | · | |
| ROE | -46.1% | -38.8% | · |
Liquidity & Solvency 4
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 15.7 | 16.9 | · | |
| Quick Ratio | 15.6 | 16.8 | · | |
| Debt / Equity | 0.1 | 0.1 | · | |
| LT Debt / Equity | 0.1 | 0.1 | · |
Valuation (TTM) 11
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Net Income TTM | $-63M | $-61M | $-36M | |
| Market Cap | $568M | $114M | · | |
| Enterprise Value | $409M | $-44M | · | |
| P/E | -8.1 | -1.7 | · | |
| P/B | 3.8 | 0.8 | · | |
| P / Tangible Book | 3.8 | 0.8 | · | |
| P / Cash Flow | -11.0 | -2.4 | · | |
| P / FCF | -11.0 | -2.3 | · | |
| EV / EBITDA | -6.2 | 0.6 | · | |
| EV / FCF | -7.9 | 0.9 | · | |
| Earnings Yield | -12.3% | -59.1% | · |
Income Statement 13
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $22M | $20M | $12M | $11M | $13M | $10M | $11M | $13M | $13M | $10M | $10M | $8M | $7M | $6M | |
| SG&A Expense | $7M | $7M | $5M | $4M | $6M | $6M | $6M | $6M | $5M | $4M | $2M | $2M | $2M | $2M | |
| Operating Expenses | $29M | $27M | $17M | $15M | $19M | $16M | $17M | $19M | $18M | $14M | $12M | $10M | $9M | $7M | |
| Operating Income | $-29M | $-27M | $-17M | $-15M | $-19M | $-16M | $-17M | $-19M | $-18M | $-14M | $-12M | $-10M | $-9M | $-7M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $2M | $738.0K | $714.0K | $667.0K | $230.0K | |
| Other Non-op | $1M | $901.0K | $873.0K | $770.0K | $976.0K | $507.0K | $2M | $2M | $2M | $969.0K | $548.0K | $577.0K | $462.0K | $-83.0K | |
| Income Tax | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-28M | $-26M | $-16M | $-14M | $-18M | $-15M | $-15M | $-17M | $-16M | $-13M | $-11M | $-9M | $-9M | $-7M | |
| EPS (Basic) | $-0.65 | $-0.80 | $-0.46 | $-0.52 | $-0.65 | $-0.56 | $-0.52 | $-0.62 | $-0.60 | $-0.76 | $-2.99 | $-2.44 | $-2.33 | $-1.97 | |
| EPS (Diluted) | $-0.65 | $-0.80 | $-0.46 | $-0.52 | $-0.65 | $-0.56 | $-0.52 | $-0.62 | $-0.60 | $-0.76 | $-2.99 | $-2.44 | $-2.33 | $-1.97 | |
| Shares (Basic) | 42,813,000 | 32,893,000 | -52,373,000 | 27,104,000 | 27,072,000 | 27,049,000 | -46,870,000 | 26,959,000 | 26,913,000 | 17,600,000 | -7,418,000 | 3,742,000 | 3,716,000 | 3,691,000 | |
| Shares (Diluted) | 42,813,000 | 32,893,000 | -52,373,000 | 27,104,000 | 27,072,000 | 27,049,000 | -46,870,000 | 26,959,000 | 26,913,000 | 17,600,000 | -7,418,000 | 3,742,000 | 3,716,000 | 3,691,000 | |
| EBITDA | $-29M | $-27M | · | $-15M | $-19M | $-16M | · | $-19M | $-18M | $-14M | · | · | · | · |
Balance Sheet 20
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $244M | $264M | $176M | $138M | $148M | $161M | $168M | $182M | $193M | $206M | $83M | · | · | · | |
| Prepaid Expense | $4M | $5M | $1M | $2M | $2M | $3M | $1M | $2M | $2M | $2M | $3M | · | · | · | |
| Other Current Assets | · | · | · | · | · | $23.0K | · | $277.0K | $148.0K | $150.0K | $112.0K | · | · | · | |
| Current Assets | $247M | $269M | $178M | $139M | $150M | $164M | $169M | $184M | $195M | $208M | $85M | · | · | · | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $2M | $1M | $2M | $1M | · | · | · | |
| Accum. Depreciation | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $909.0K | $791.0K | $781.0K | $684.0K | · | · | · | |
| Total Assets | $254M | $276M | $185M | $147M | $158M | $172M | $178M | $192M | $197M | $210M | $87M | · | · | · | |
| Accounts Payable | $4M | $3M | $2M | $2M | $2M | $1M | $2M | $2M | $2M | $2M | $1M | · | · | · | |
| Accrued Liabilities | $9M | $8M | $9M | $7M | $6M | $6M | $8M | $8M | $6M | $4M | $5M | · | · | · | |
| Current Liabilities | $17M | $13M | $11M | $9M | $8M | $7M | $10M | $14M | $10M | $8M | $6M | · | · | · | |
| Capital Leases | $3M | $4M | $4M | $4M | $4M | $4M | $5M | $5M | · | · | $0 | · | · | · | |
| Total Liabilities | $35M | $33M | $34M | $35M | $34M | $33M | $26M | $27M | $18M | $17M | $17M | · | · | · | |
| Long-term Debt | $16M | $16M | $17M | · | · | · | $10M | $10M | $10M | $10M | · | · | · | · | |
| Total Debt | $16M | $16M | · | $20M | $20M | $20M | · | $10M | $10M | $10M | · | · | · | · | |
| Paid-in Capital | $475M | $471M | $353M | $297M | $295M | $293M | $290M | $288M | $286M | $284M | $5M | · | · | · | |
| Retained Earnings | $-256M | $-228M | $-202M | $-185M | $-171M | $-154M | $-138M | $-123M | $-106M | $-90M | $-77M | · | · | · | |
| AOCI | $17.0K | $13.0K | $22.0K | $14.0K | $31.0K | $14.0K | $-101.0K | $-95.0K | $-89.0K | $-84.0K | $-79.0K | · | · | · | |
| Stockholders' Equity | $219M | $243M | $151M | $112M | $123M | $139M | $151M | $165M | $180M | $193M | $-72M | · | · | · | |
| Liabilities + Equity | $254M | $276M | $185M | $147M | $158M | $172M | $178M | $192M | $197M | $210M | $87M | · | · | · | |
| Shares Outstanding | 35,094,000 | 35,053,000 | 31,924,000 | 27,168,000 | 27,072,000 | 27,072,000 | 26,987,000 | 26,968,000 | 26,951,000 | 26,884,000 | 3,832,000 | · | · | · |
Cash Flow 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | $100.0K | $171.0K | · | $200.0K | $100.0K | $97.0K | $87.0K | $100.0K | $100.0K | $86.0K | |
| Stock-based Comp | $4M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $606.0K | $541.0K | $1M | $484.0K | |
| Other Non-cash | · | · | · | · | · | $-4M | · | · | · | $158.0K | · | · | · | · | |
| Operating Cash Flow | $-20M | $-27M | $-12M | $-10M | $-14M | $-17M | $-13M | $-12M | $-12M | $-11M | $-12M | $-8M | $-7M | $-8M | |
| CapEx | $0 | $556.0K | $0 | $0 | $0 | $24.0K | $506.0K | $1M | $340.0K | $224.0K | $352.0K | $43.0K | $54.0K | $21.0K | |
| Investing Cash Flow | $0 | $-556.0K | $0 | $0 | $0 | $-24.0K | $-506.0K | $-1M | $-340.0K | $-224.0K | $-352.0K | $-43.0K | $-54.0K | $-21.0K | |
| Debt Issued | · | · | · | · | · | $20M | · | · | · | $0 | · | · | · | · | |
| Net Debt Issued | · | $0 | · | · | · | $9M | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-273.0K | $115M | $50M | $153.0K | $613.0K | $9M | $49.0K | $1M | $-234.0K | $135M | $43M | $49.0K | $-51.0K | $25M | |
| Net Change in Cash | $-20M | $87M | $39M | $-10M | $-13M | $-7M | $-13M | $-11M | $-12M | $123M | $31M | $-8M | $-7M | $17M | |
| Free Cash Flow | · | $-28M | · | · | · | $-17M | · | · | · | $-11M | · | · | · | · |
Profitability 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -13.4% | -11.7% | · | -8.4% | -10.0% | -8.0% | · | -17.5% | -16.2% | -12.8% | · | · | · | · | |
| ROE | -16.1% | -13.7% | · | -10.2% | -11.7% | -9.1% | · | -20.3% | -17.8% | -13.9% | · | · | · | · |
Liquidity & Solvency 4
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 15.4 | 18.4 | 22.5 | · | 13.1 | 19.9 | 26.0 | · | · | · | · | |
| Quick Ratio | 14.6 | 20.1 | · | 15.2 | 18.2 | 22.2 | · | 13.0 | 19.6 | 25.7 | · | · | · | · | |
| Debt / Equity | 0.1 | 0.1 | · | 0.2 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | · | · | · | |
| LT Debt / Equity | 0.1 | 0.1 | · | 0.2 | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | · | · | · |
Valuation (TTM) 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-86M | $-73M | · | $-64M | $-66M | $-61M | · | $-55M | $-47M | $-39M | · | · | · | · | |
| Market Cap | $926M | $788M | · | $109M | $60M | $58M | · | $309M | $288M | $413M | · | · | · | · | |
| Enterprise Value | $699M | $540M | · | $-8M | $-68M | $-82M | · | $137M | $105M | $217M | · | · | · | · | |
| P/E | -10.1 | -8.9 | · | -1.7 | -0.9 | -0.9 | · | -2.6 | -1.7 | -2.0 | · | · | · | · | |
| P/B | 4.2 | 3.2 | · | 1.0 | 0.5 | 0.4 | · | 1.9 | 1.6 | 2.1 | · | · | · | · | |
| P / Tangible Book | 4.2 | 3.2 | · | 1.0 | 0.5 | 0.4 | · | 1.9 | 1.6 | 2.1 | · | · | · | · | |
| P / Cash Flow | · | -29.1 | · | · | · | -3.5 | · | · | · | -37.6 | · | · | · | · | |
| P / FCF | · | -28.5 | · | · | · | -3.5 | · | · | · | -36.8 | · | · | · | · | |
| EV / EBITDA | -24.0 | -19.9 | · | 0.6 | 3.7 | 5.3 | · | -7.3 | -5.8 | -15.2 | · | · | · | · | |
| EV / FCF | · | -19.5 | · | · | · | 5.0 | · | · | · | -19.3 | · | · | · | · | |
| Earnings Yield | -9.9% | -11.2% | · | -58.5% | -110.5% | -117.6% | · | -38.6% | -57.3% | -48.9% | · | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Net Income | $-63M | $-61M | $-36M |
| Diluted EPS | $-2.19 | $-2.50 | $-9.73 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Debt / Equity | 0.1 | 0.1 | — |
| Current Ratio | 15.7 | 16.9 | — |
| Quick Ratio | 15.6 | 16.8 | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Free Cash Flow | $-52M | $-49M | — |
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Institutional owners (13F) 124 filers · $704.0M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 31 (+8 vs prior Q) | 21 (+15 vs prior Q) | 33 (+2 vs prior Q) | 32 (-7 vs prior Q) | +1.6M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Alpha Wave Global, LP | $97,847,707 | 3,707,757 | 13.90% | Shares |
| Commodore Capital LP | $71,865,142 | 2,723,196 | 10.21% | Shares |
| PERCEPTIVE ADVISORS LLC | $42,485,076 | 1,609,893 | 6.03% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42,224,000 | 1,600,000 | 6.00% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $36,668,298 | 1,389,477 | 5.21% | Shares |
| Spruce Street Capital LP | $35,706,910 | 1,353,047 | 5.07% | Shares |
| Vivo Capital, LLC | $31,901,763 | 1,208,858 | 4.53% | Shares |
| FRANKLIN RESOURCES INC | $26,741,172 | 1,013,307 | 3.80% | Shares |
| ARMISTICE CAPITAL, LLC | $22,800,960 | 864,000 | 3.24% | Shares |
| Affinity Asset Advisors, LLC | $22,431,500 | 850,000 | 3.19% | Shares |
| VANGUARD GROUP INC | $21,272,282 | 1,195,072 | 3.02% | Shares |
| Vestal Point Capital, LP | $20,716,150 | 785,000 | 2.94% | Shares |
| STATE STREET CORP | $18,102,089 | 685,945 | 2.57% | Shares |
| 72 Investment Holdings, LLC | $17,622,661 | 667,778 | 2.50% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $15,091,591 | 571,698 | 2.14% | Shares |
| MILLENNIUM MANAGEMENT LLC | $14,734,065 | 558,320 | 2.09% | Shares |
| Point72 Asset Management, L.P. | $13,272,851 | 502,950 | 1.89% | Shares |
| Integral Health Asset Management, LLC | $13,195,000 | 500,000 | 1.87% | Shares |
| Venrock Adviser, LLC | $13,195,000 | 500,000 | 1.87% | Shares |
| Driehaus Capital Management LLC | $12,867,131 | 487,576 | 1.83% | Shares |
| Parkman Healthcare Partners LLC | $11,322,234 | 429,035 | 1.61% | Shares |
| Ikarian Capital, LLC | $10,749,651 | 407,338 | 1.53% | Shares |
| ORBIMED ADVISORS LLC | $6,804,714 | 257,852 | 0.97% | Shares |
| Schonfeld Strategic Advisors LLC | $6,798,881 | 257,631 | 0.97% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $5,575,072 | 211,257 | 0.79% | Shares |
| GOLDMAN SACHS GROUP INC | $5,093,059 | 192,992 | 0.72% | Shares |
| AMERIPRISE FINANCIAL INC | $5,040,385 | 190,996 | 0.72% | Shares |
| Saturn V Capital Management LP | $4,824,857 | 182,829 | 0.69% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4,779,255 | 181,101 | 0.68% | Shares |
| TWO SIGMA INVESTMENTS, LP | $3,887,221 | 147,299 | 0.55% | Shares |
| Eversept Partners, LP | $3,385,468 | 128,286 | 0.48% | Shares |
| TWO SIGMA ADVISERS, LP | $2,849,780 | 160,100 | 0.40% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,803,515 | 106,234 | 0.40% | Shares |
| ALKEON CAPITAL MANAGEMENT LLC | $2,694,445 | 102,101 | 0.38% | Shares |
| STIFEL FINANCIAL CORP | $2,255,827 | 85,480 | 0.32% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2,126,585 | 80,583 | 0.30% | Shares |
| AWM Investment Company, Inc. | $2,111,200 | 80,000 | 0.30% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,884,220 | 71,399 | 0.27% | Shares |
| AdvisorShares Investments LLC | $1,867,040 | 70,748 | 0.27% | Shares |
| UBS Group AG | $1,549,014 | 58,697 | 0.22% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1,336,733 | 50,653 | 0.19% | Shares |
| XTX Topco Ltd | $1,229,800 | 46,601 | 0.17% | Shares |
| TD Asset Management Inc | $1,155,882 | 43,800 | 0.16% | Shares |
| Quantinno Capital Management LP | $1,017,493 | 38,556 | 0.14% | Shares |
| ALPS ADVISORS INC | $939,827 | 35,613 | 0.13% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $933,467 | 35,372 | 0.13% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $881,426 | 33,400 | 0.13% | Call option |
| RHUMBLINE ADVISERS | $834,866 | 31,636 | 0.12% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $797,849 | 30,233 | 0.11% | Shares |
| Bank of New York Mellon Corp | $775,206 | 29,375 | 0.11% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $736,281 | 27,900 | 0.10% | Put option |
| AMERICAN CENTURY COMPANIES INC | $707,780 | 26,820 | 0.10% | Shares |
| BROWN ADVISORY INC | $659,750 | 25,000 | 0.09% | Shares |
| Allianz Asset Management GmbH | $640,680 | 28,500 | 0.09% | Shares |
| JANE STREET GROUP, LLC | $622,804 | 23,600 | 0.09% | Call option |
| ALLIANCEBERNSTEIN L.P. | $613,704 | 27,300 | 0.09% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $592,587 | 22,455 | 0.08% | Shares |
| Nuveen Asset Management, LLC | $592,001 | 139,953 | 0.08% | Shares |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | $585,198 | 22,175 | 0.08% | Shares |
| Squarepoint Ops LLC | $561,738 | 21,286 | 0.08% | Shares |
| CITIGROUP INC | $507,585 | 19,234 | 0.07% | Shares |
| BANK OF AMERICA CORP /DE/ | $504,076 | 19,101 | 0.07% | Shares |
| Revisor Wealth Management LLC | $452,060 | 17,130 | 0.06% | Shares |
| SCS Capital Management LLC | $444,408 | 16,840 | 0.06% | Shares |
| MetLife Investment Management, LLC | $412,845 | 15,644 | 0.06% | Shares |
| Virtus Investment Advisers, LLC | $402,157 | 15,239 | 0.06% | Shares |
| CITADEL ADVISORS LLC | $398,489 | 15,100 | 0.06% | Call option |
| BANK OF NOVA SCOTIA | $380,016 | 14,400 | 0.05% | Shares |
| Laird Norton Wetherby Wealth Management, LLC | $338,332 | 84,162 | 0.05% | Shares |
| Vanguard Personalized Indexing Management, LLC | $334,045 | 12,658 | 0.05% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $316,918 | 12,009 | 0.05% | Shares |
| BARCLAYS PLC | $296,492 | 11,235 | 0.04% | Shares |
| BlackRock, Inc. | $294,249 | 11,150 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $281,027 | 10,649 | 0.04% | Shares |
| Invesco Ltd. | $275,591 | 10,443 | 0.04% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $242,788 | 9,200 | 0.03% | Shares |
| GK Wealth Management LLC | $226,030 | 8,565 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $211,067 | 7,998 | 0.03% | Shares |
| IEQ CAPITAL, LLC | $210,803 | 7,988 | 0.03% | Shares |
| PROFUND ADVISORS LLC | $208,692 | 7,908 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $203,863 | 7,725 | 0.03% | Shares |
| Persistent Asset Partners Ltd | $203,150 | 7,698 | 0.03% | Shares |
| State of Wyoming | $202,781 | 7,684 | 0.03% | Shares |
| MORGAN STANLEY | $189,823 | 7,193 | 0.03% | Shares |
| FMR LLC | $166,600 | 6,313 | 0.02% | Shares |
| Nuveen, LLC | $150,687 | 5,710 | 0.02% | Shares |
| NORTHERN TRUST CORP | $108,595 | 4,115 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $102,393 | 3,880 | 0.01% | Shares |
| AlphaQuest LLC | $68,014 | 3,821 | 0.01% | Shares |
| Legal & General Group Plc | $67,110 | 2,543 | 0.01% | Shares |
| WHITTIER TRUST CO OF NEVADA INC | $63,787 | 2,482 | 0.01% | Shares |
| WELLS FARGO & COMPANY/MN | $63,626 | 2,411 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $62,729 | 2,377 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $48,162 | 1,825 | 0.01% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $26,548 | 1,006 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $26,000 | 975 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $18,077 | 685 | 0.00% | Shares |
| STRS OHIO | $15,834 | 600 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $14,412 | 533 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $13,406 | 508 | 0.00% | Shares |
ETF ownership Held by 18 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 0.91% | 2,461 SH | Aug. 8, 2026 | Daily |
| PILL · Direxion Shares ETF Trust | 0.43% | 2,143 NS | April 30, 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 0.40% | 32,025 NS | May 31, 2026 | N-PORT |
| IWC · iShares Trust | 0.17% | 89,132 SH | Aug. 8, 2026 | Daily |
| IBB · iShares Trust | 0.08% | 258,431 SH | Aug. 8, 2026 | Daily |
| IWO · iShares Trust | 0.05% | 234,571 SH | Aug. 8, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.04% | 28,057 SH | Aug. 8, 2026 | Daily |
| IWM · iShares Trust | 0.02% | 658,731 SH | Aug. 8, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.02% | 150,871 SH | Aug. 8, 2026 | Daily |
| ISCB · iShares Trust | 0.01% | 1,473 SH | Aug. 8, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 346,522 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.01% | 11,271 NS | May 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 1,813 NS | April 30, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 37,715 SH | Aug. 8, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 7,644 SH | Aug. 8, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.00% | 823 NS | April 30, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1,011,881 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 2,173 SH | Aug. 8, 2026 | Daily |