ANRO Alto Neuroscience, Inc. Common Stock
NYSE · Pharmaceuticals · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 12, 2026
$24.80
· of 52w range
· above low
· to high
$4.7152w low
$37.4852w high
Market Cap (MRQ)
$870M
P/E
-12.4
EPS
$-2.19
your badges
52W Range
$5–$37
Analyst Rating
STRONG BUY
Price Target
$38
P/E
-12.4
ROE
-46.1%
Net Profit Margin
·
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ANRO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$24.80
Market Cap (MRQ)
$870M
P/E
-12.4
EPS
$-2.19
ROE
-46.1%
Debt/Equity (MRQ)
0.1
52W Range
$5–$37
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10-Year Performance Revenue, net income, margins and EPS trends
EPS$-2.192023-12-31 → 2025-12-31
Free Cash Flow$-52M2024-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | ANRO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -12.4 | · | · | · | |
| P/B (MRQ) | 4.0 | · | · | · | |
| EV / EBITDA | -10.7 | · | · | · | |
| Price / FCF (TTM) | -12.6 | · | · | · | |
| Price / Cash Flow (TTM) | -12.7 | · | · | · | |
| EV / FCF | -13.7 | · | · | · | |
| Price / Tangible Book | 5.8 | · | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | ANRO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -34.9% | · | · | · | |
| ROE | -46.1% | · | · | · |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | ANRO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Debt / Equity (MRQ) | 0.1 | · | · | · | |
| Current Ratio (MRQ) | 14.9 | · | · | · | |
| Quick Ratio | 15.6 | · | · | · | |
| Long-Term Debt / Equity (MRQ) | 0.1 | · | · | · |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-1.8%
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | $-0.65 | $-0.75 | 13.2% | |
| March 31, 2026 | $-0.80 | $-0.55 | -46.2% | |
| Dec. 31, 2025 | $-0.58 | $-0.54 | -7.1% | |
| Sept. 30, 2025 | $-0.52 | $-0.68 | 23.7% | |
| June 30, 2025 | $-0.65 | $-0.63 | -4.0% | |
| March 31, 2025 | $-0.56 | $-0.62 | 9.7% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| R&D Expense | $46M | $47M | $30M | |
| SG&A Expense | $21M | $22M | $8M | |
| Operating Expenses | $66M | $69M | $38M | |
| Operating Income | $-66M | $-69M | $-38M | |
| Interest Income | $7M | $9M | $2M | |
| Other Non-op | $3M | $7M | $2M | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-63M | $-61M | $-36M | |
| EPS (Basic) | $-2.19 | $-2.50 | $-9.73 | |
| EPS (Diluted) | $-2.19 | $-2.50 | $-9.73 | |
| Shares (Basic) | 28,852,000 | 24,602,000 | 3,731,000 | |
| Shares (Diluted) | 28,852,000 | 24,602,000 | 3,731,000 | |
| EBITDA | $-66M | $-68M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $176M | $168M | $83M | |
| Prepaid Expense | $1M | $1M | $3M | |
| Other Current Assets | · | $30.0K | $112.0K | |
| Current Assets | $178M | $169M | $85M | |
| PP&E (Net) | $2M | $3M | $1M | |
| Accum. Depreciation | $2M | $1M | $684.0K | |
| Total Assets | $185M | $178M | $87M | |
| Accounts Payable | $2M | $2M | $1M | |
| Accrued Liabilities | $9M | $8M | $5M | |
| Current Liabilities | $11M | $10M | $6M | |
| Capital Leases | $4M | $5M | $0 | |
| Total Liabilities | $34M | $26M | $17M | |
| Long-term Debt | $17M | $10M | $10M | |
| Total Debt | $17M | $10M | · | |
| Paid-in Capital | $353M | $290M | $5M | |
| Retained Earnings | $-202M | $-138M | $-77M | |
| AOCI | $22.0K | $-101.0K | $-79.0K | |
| Stockholders' Equity | $151M | $151M | $-72M | |
| Liabilities + Equity | $185M | $178M | $87M | |
| Shares Outstanding | 31,924,000 | 26,987,000 | 3,832,000 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | · | $502.0K | $373.0K | |
| Stock-based Comp | $8M | $8M | $3M | |
| Other Non-cash | · | $6M | · | |
| Operating Cash Flow | $-52M | $-47M | $-33M | |
| CapEx | $24.0K | $2M | $470.0K | |
| Investing Cash Flow | $-24.0K | $-2M | $-470.0K | |
| Net Debt Issued | $-10M | · | · | |
| Financing Cash Flow | $60M | $136M | $68M | |
| Net Change in Cash | $8M | $86M | $34M | |
| Free Cash Flow | $-52M | $-49M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| ROA | -34.9% | -46.5% | · | |
| ROE | -46.1% | -38.8% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 15.7 | 16.9 | · | |
| Quick Ratio | 15.6 | 16.8 | · | |
| Debt / Equity | 0.1 | 0.1 | · | |
| LT Debt / Equity | 0.1 | 0.1 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Book Value / Share | $4.73 | $5.61 | · | |
| Cash Flow / Share | $-1.79 | $-1.93 | · | |
| Cash / Share | $5.53 | $6.23 | · | |
| EPS (TTM) | $-2.19 | $-2.50 | $-9.73 |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Net Income TTM | $-63M | $-61M | $-36M | |
| Market Cap | $568M | $114M | · | |
| Enterprise Value | $409M | $-44M | · | |
| P/E | -8.1 | -1.7 | · | |
| P/B | 3.8 | 0.8 | · | |
| P / Tangible Book | 3.8 | 0.8 | · | |
| P / Cash Flow | -11.0 | -2.4 | · | |
| P / FCF | -11.0 | -2.3 | · | |
| EV / EBITDA | -6.2 | 0.6 | · | |
| EV / FCF | -7.9 | 0.9 | · | |
| Earnings Yield | -12.3% | -59.1% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $22M | $20M | $12M | $11M | $13M | $10M | $11M | $13M | $13M | $10M | $10M | $8M | $7M | $6M | |
| SG&A Expense | $7M | $7M | $5M | $4M | $6M | $6M | $6M | $6M | $5M | $4M | $2M | $2M | $2M | $2M | |
| Operating Expenses | $29M | $27M | $17M | $15M | $19M | $16M | $17M | $19M | $18M | $14M | $12M | $10M | $9M | $7M | |
| Operating Income | $-29M | $-27M | $-17M | $-15M | $-19M | $-16M | $-17M | $-19M | $-18M | $-14M | $-12M | $-10M | $-9M | $-7M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $2M | $738.0K | $714.0K | $667.0K | $230.0K | |
| Other Non-op | $1M | $901.0K | $873.0K | $770.0K | $976.0K | $507.0K | $2M | $2M | $2M | $969.0K | $548.0K | $577.0K | $462.0K | $-83.0K | |
| Income Tax | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-28M | $-26M | $-16M | $-14M | $-18M | $-15M | $-15M | $-17M | $-16M | $-13M | $-11M | $-9M | $-9M | $-7M | |
| EPS (Basic) | $-0.65 | $-0.80 | $-0.46 | $-0.52 | $-0.65 | $-0.56 | $-0.52 | $-0.62 | $-0.60 | $-0.76 | $-2.99 | $-2.44 | $-2.33 | $-1.97 | |
| EPS (Diluted) | $-0.65 | $-0.80 | $-0.46 | $-0.52 | $-0.65 | $-0.56 | $-0.52 | $-0.62 | $-0.60 | $-0.76 | $-2.99 | $-2.44 | $-2.33 | $-1.97 | |
| Shares (Basic) | 42,813,000 | 32,893,000 | · | 27,104,000 | 27,072,000 | 27,049,000 | · | 26,959,000 | 26,913,000 | 17,600,000 | · | 3,742,000 | 3,716,000 | 3,691,000 | |
| Shares (Diluted) | 42,813,000 | 32,893,000 | · | 27,104,000 | 27,072,000 | 27,049,000 | · | 26,959,000 | 26,913,000 | 17,600,000 | · | 3,742,000 | 3,716,000 | 3,691,000 | |
| EBITDA | $-29M | $-27M | · | $-15M | $-19M | $-16M | · | $-19M | $-18M | $-14M | · | · | · | · |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $244M | $264M | $176M | $138M | $148M | $161M | $168M | $182M | $193M | $206M | $83M | · | · | · | |
| Prepaid Expense | $4M | $5M | $1M | $2M | $2M | $3M | $1M | $2M | $2M | $2M | $3M | · | · | · | |
| Other Current Assets | · | · | · | · | · | $23.0K | · | $277.0K | $148.0K | $150.0K | $112.0K | · | · | · | |
| Current Assets | $247M | $269M | $178M | $139M | $150M | $164M | $169M | $184M | $195M | $208M | $85M | · | · | · | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $2M | $1M | $2M | $1M | · | · | · | |
| Accum. Depreciation | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $909.0K | $791.0K | $781.0K | $684.0K | · | · | · | |
| Total Assets | $254M | $276M | $185M | $147M | $158M | $172M | $178M | $192M | $197M | $210M | $87M | · | · | · | |
| Accounts Payable | $4M | $3M | $2M | $2M | $2M | $1M | $2M | $2M | $2M | $2M | $1M | · | · | · | |
| Accrued Liabilities | $9M | $8M | $9M | $7M | $6M | $6M | $8M | $8M | $6M | $4M | $5M | · | · | · | |
| Current Liabilities | $17M | $13M | $11M | $9M | $8M | $7M | $10M | $14M | $10M | $8M | $6M | · | · | · | |
| Capital Leases | $3M | $4M | $4M | $4M | $4M | $4M | $5M | $5M | · | · | $0 | · | · | · | |
| Total Liabilities | $35M | $33M | $34M | $35M | $34M | $33M | $26M | $27M | $18M | $17M | $17M | · | · | · | |
| Long-term Debt | $16M | $16M | $17M | · | · | · | $10M | $10M | $10M | $10M | · | · | · | · | |
| Total Debt | $16M | $16M | · | $20M | $20M | $20M | · | $10M | $10M | $10M | · | · | · | · | |
| Paid-in Capital | $475M | $471M | $353M | $297M | $295M | $293M | $290M | $288M | $286M | $284M | $5M | · | · | · | |
| Retained Earnings | $-256M | $-228M | $-202M | $-185M | $-171M | $-154M | $-138M | $-123M | $-106M | $-90M | $-77M | · | · | · | |
| AOCI | $17.0K | $13.0K | $22.0K | $14.0K | $31.0K | $14.0K | $-101.0K | $-95.0K | $-89.0K | $-84.0K | $-79.0K | · | · | · | |
| Stockholders' Equity | $219M | $243M | $151M | $112M | $123M | $139M | $151M | $165M | $180M | $193M | $-72M | · | · | · | |
| Liabilities + Equity | $254M | $276M | $185M | $147M | $158M | $172M | $178M | $192M | $197M | $210M | $87M | · | · | · | |
| Shares Outstanding | 35,094,000 | 35,053,000 | 31,924,000 | 27,168,000 | 27,072,000 | 27,072,000 | 26,987,000 | 26,968,000 | 26,951,000 | 26,884,000 | 3,832,000 | · | · | · |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | $100.0K | $171.0K | · | $200.0K | $100.0K | $97.0K | $87.0K | $100.0K | $100.0K | $86.0K | |
| Stock-based Comp | $4M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $606.0K | $541.0K | $1M | $484.0K | |
| Other Non-cash | · | · | · | · | · | $-4M | · | · | · | $158.0K | · | · | · | · | |
| Operating Cash Flow | $-20M | $-27M | $-12M | $-10M | $-14M | $-17M | $-13M | $-12M | $-12M | $-11M | $-12M | $-8M | $-7M | $-8M | |
| CapEx | $0 | $556.0K | $0 | $0 | $0 | $24.0K | $506.0K | $1M | $340.0K | $224.0K | $352.0K | $43.0K | $54.0K | $21.0K | |
| Investing Cash Flow | $0 | $-556.0K | $0 | $0 | $0 | $-24.0K | $-506.0K | $-1M | $-340.0K | $-224.0K | $-352.0K | $-43.0K | $-54.0K | $-21.0K | |
| Debt Issued | · | · | · | · | · | $20M | · | · | · | $0 | · | · | · | · | |
| Net Debt Issued | · | $0 | · | · | · | $9M | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-273.0K | $115M | $50M | $153.0K | $613.0K | $9M | $49.0K | $1M | $-234.0K | $135M | $43M | $49.0K | $-51.0K | $25M | |
| Net Change in Cash | $-20M | $87M | $39M | $-10M | $-13M | $-7M | $-13M | $-11M | $-12M | $123M | $31M | $-8M | $-7M | $17M | |
| Free Cash Flow | · | $-28M | · | · | · | $-17M | · | · | · | $-11M | · | · | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -13.4% | -11.7% | · | -8.4% | -10.0% | -8.0% | · | -17.5% | -16.2% | -12.8% | · | · | · | · | |
| ROE | -16.1% | -13.7% | · | -10.2% | -11.7% | -9.1% | · | -20.3% | -17.8% | -13.9% | · | · | · | · |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 15.4 | 18.4 | 22.5 | · | 13.1 | 19.9 | 26.0 | · | · | · | · | |
| Quick Ratio | 14.6 | 20.1 | · | 15.2 | 18.2 | 22.2 | · | 13.0 | 19.6 | 25.7 | · | · | · | · | |
| Debt / Equity | 0.1 | 0.1 | · | 0.2 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | · | · | · | |
| LT Debt / Equity | 0.1 | 0.1 | · | 0.2 | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $6.25 | $6.94 | · | $4.11 | $4.56 | $5.14 | · | $6.12 | $6.67 | $7.18 | · | · | · | · | |
| Cash Flow / Share | · | $-0.82 | · | · | · | $-0.61 | · | · | · | $-0.62 | · | · | · | · | |
| Cash / Share | $6.95 | $7.52 | · | $5.07 | $5.45 | $5.94 | · | $6.74 | $7.17 | $7.66 | · | · | · | · | |
| EPS (TTM) | $-2.43 | $-2.43 | · | $-2.25 | $-2.35 | $-2.30 | · | $-4.97 | $-6.79 | $-8.52 | · | · | · | · |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-84M | $-74M | · | $-62M | $-65M | $-63M | · | $-57M | $-50M | $-42M | · | · | · | · | |
| Market Cap | $926M | $788M | · | $109M | $60M | $58M | · | $309M | $288M | $413M | · | · | · | · | |
| Enterprise Value | $699M | $540M | · | $-8M | $-68M | $-82M | · | $137M | $105M | $217M | · | · | · | · | |
| P/E | -10.9 | -9.3 | · | -1.8 | -0.9 | -0.9 | · | -2.3 | -1.6 | -1.8 | · | · | · | · | |
| P/B | 4.2 | 3.2 | · | 1.0 | 0.5 | 0.4 | · | 1.9 | 1.6 | 2.1 | · | · | · | · | |
| P / Tangible Book | 4.2 | 3.2 | · | 1.0 | 0.5 | 0.4 | · | 1.9 | 1.6 | 2.1 | · | · | · | · | |
| P / Cash Flow | · | -29.1 | · | · | · | -3.5 | · | · | · | -37.6 | · | · | · | · | |
| Earnings Yield | -9.2% | -10.8% | · | -56.0% | -106.8% | -106.5% | · | -43.4% | -63.5% | -55.5% | · | · | · | · |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Net Income | $-63M | $-61M | $-36M |
| Diluted EPS | $-2.19 | $-2.50 | $-9.73 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Debt / Equity | 0.1 | 0.1 | · |
| Current Ratio | 15.7 | 16.9 | · |
| Quick Ratio | 15.6 | 16.8 | · |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Free Cash Flow | $-52M | $-49M | · |
Institutional owners (13F) 123 filers · $796.9M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
123
Value held
$796.9M
New positions
28
Exited positions
21
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 28 (+2 vs prior Q) | 21 (+15 vs prior Q) | 39 (+9 vs prior Q) | 31 (-11 vs prior Q) | +2.3M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Alpha Wave Global, LP | $97,847,707 | 3,707,757 | 12.28% | Shares |
| Commodore Capital LP | $71,865,142 | 2,723,196 | 9.02% | Shares |
| BlackRock, Inc. | $55,973,428 | 2,121,009 | 7.02% | Shares |
| PERCEPTIVE ADVISORS LLC | $42,485,076 | 1,609,893 | 5.33% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42,224,000 | 1,600,000 | 5.30% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $36,668,298 | 1,389,477 | 4.60% | Shares |
| Spruce Street Capital LP | $35,706,910 | 1,353,047 | 4.48% | Shares |
| Vivo Capital, LLC | $31,901,763 | 1,208,858 | 4.00% | Shares |
| FRANKLIN RESOURCES INC | $26,741,172 | 1,013,307 | 3.36% | Shares |
| VANGUARD GROUP INC | $24,312,077 | 1,365,847 | 3.05% | Shares |
| ARMISTICE CAPITAL, LLC | $22,800,960 | 864,000 | 2.86% | Shares |
| Affinity Asset Advisors, LLC | $22,431,500 | 850,000 | 2.81% | Shares |
| Vestal Point Capital, LP | $20,716,150 | 785,000 | 2.60% | Shares |
| STATE STREET CORP | $18,102,089 | 685,945 | 2.27% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $17,902,152 | 678,199 | 2.25% | Shares |
| 72 Investment Holdings, LLC | $17,622,661 | 667,778 | 2.21% | Shares |
| NORTHERN TRUST CORP | $16,696,980 | 632,701 | 2.10% | Shares |
| MILLENNIUM MANAGEMENT LLC | $14,734,065 | 558,320 | 1.85% | Shares |
| Point72 Asset Management, L.P. | $13,272,851 | 502,950 | 1.67% | Shares |
| Integral Health Asset Management, LLC | $13,195,000 | 500,000 | 1.66% | Shares |
| Venrock Adviser, LLC | $13,195,000 | 500,000 | 1.66% | Shares |
| Driehaus Capital Management LLC | $12,867,131 | 487,576 | 1.61% | Shares |
| Parkman Healthcare Partners LLC | $11,322,234 | 429,035 | 1.42% | Shares |
| Ikarian Capital, LLC | $10,749,651 | 407,338 | 1.35% | Shares |
| ORBIMED ADVISORS LLC | $6,804,714 | 257,852 | 0.85% | Shares |
| Schonfeld Strategic Advisors LLC | $6,798,881 | 257,631 | 0.85% | Shares |
| GOLDMAN SACHS GROUP INC | $6,249,944 | 236,830 | 0.78% | Shares |
| MARSHALL WACE, LLP | $5,951,025 | 225,503 | 0.75% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $5,575,072 | 211,257 | 0.70% | Shares |
| AMERIPRISE FINANCIAL INC | $5,040,385 | 190,996 | 0.63% | Shares |
| Saturn V Capital Management LP | $4,824,857 | 182,829 | 0.61% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4,779,255 | 181,101 | 0.60% | Shares |
| TWO SIGMA INVESTMENTS, LP | $3,887,221 | 147,299 | 0.49% | Shares |
| Eversept Partners, LP | $3,385,468 | 128,286 | 0.42% | Shares |
| TWO SIGMA ADVISERS, LP | $2,849,780 | 160,100 | 0.36% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,803,515 | 106,234 | 0.35% | Shares |
| ALKEON CAPITAL MANAGEMENT LLC | $2,694,445 | 102,101 | 0.34% | Shares |
| STIFEL FINANCIAL CORP | $2,255,827 | 85,480 | 0.28% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2,126,585 | 80,583 | 0.27% | Shares |
| AWM Investment Company, Inc. | $2,111,200 | 80,000 | 0.26% | Shares |
| Bank of New York Mellon Corp | $2,014,348 | 76,330 | 0.25% | Shares |
| MORGAN STANLEY | $1,977,666 | 74,940 | 0.25% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,884,220 | 71,399 | 0.24% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $1,871,393 | 70,913 | 0.23% | Shares |
| AdvisorShares Investments LLC | $1,867,040 | 70,748 | 0.23% | Shares |
| Nuveen, LLC | $1,645,205 | 62,342 | 0.21% | Shares |
| UBS Group AG | $1,549,014 | 58,697 | 0.19% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1,336,733 | 50,653 | 0.17% | Shares |
| XTX Topco Ltd | $1,229,800 | 46,601 | 0.15% | Shares |
| TD Asset Management Inc | $1,155,882 | 43,800 | 0.15% | Shares |
Company insiders 12 insiders · 4 officers · 9 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Amit Etkin | PRESIDENT AND CEO | May 14, 2026 G | 833,949 | 0 | 0 | $0 |
| Nicholas Conrad Smith | PRESIDENT AND CFO | Sept. 30, 2026 M | 24,060 | 0 | 3 | $-3,566,991 |
| Jr. Michael Conick Hanley | CHIEF OPERATING OFFICER | Feb. 11, 2026 A | · | 0 | 0 | $0 |
| Adam Savitz | CHIEF MEDICAL OFFICER | Feb. 11, 2026 A | 39,851 | 0 | 0 | $0 |
| Andrew Craig Miller | Director | May 27, 2026 A | · | 0 | 0 | $0 |
| Husseini Manji | Director | May 12, 2026 A | · | 0 | 0 | $0 |
| Gwill York | Director | May 12, 2026 A | 23,917 | 0 | 0 | $0 |
| Christopher Nixon Cox | Director | May 12, 2026 A | 715,653 | 0 | 0 | $0 |
| Ramiro Sanchez | Director | May 12, 2026 A | · | 0 | 0 | $0 |
| Andrew Dreyfus | Director | May 12, 2026 A | · | 0 | 0 | $0 |
| Maha Radhakrishnan | Director | March 8, 2024 A | · | 0 | 0 | $0 |
| Po Yu (Jeff) Chen | Director | Feb. 6, 2024 C | 47,709 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 20 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 1.04% | 2,461 SH | Sept. 11, 2026 | Daily |
| PILL · Direxion Shares ETF Trust | 0.90% | 6,833 NS | July 31, 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0.84% | 14,476 NS | July 31, 2026 | N-PORT |
| IWC · iShares Trust | 0.20% | 88,973 SH | Sept. 11, 2026 | Daily |
| IBB · iShares Trust | 0.08% | 269,543 SH | Sept. 11, 2026 | Daily |
| IWO · iShares Trust | 0.05% | 244,377 SH | Sept. 11, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.04% | 28,057 SH | Aug. 19, 2026 | Daily |
| IWM · iShares Trust | 0.03% | 671,421 SH | Sept. 11, 2026 | Daily |
| RSSL · Global X Funds | 0.02% | 12,479 NS | July 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.02% | 150,871 SH | Aug. 19, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 346,522 SH | Aug. 19, 2026 | Daily |
| WSML · iShares Trust | 0.01% | 1,512 SH | Sept. 11, 2026 | Daily |
| DCOR · Dimensional ETF Trust | 0.00% | 1,813 NS | July 31, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 37,712 SH | Sept. 11, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 7,724 SH | Sept. 11, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.00% | 2,765 NS | July 31, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 1,273 NS | July 31, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1,011,881 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 2,173 SH | Aug. 19, 2026 | Daily |
| ISCB · iShares Trust | · | 1,473 SH | Sept. 11, 2026 | Daily |
ANRO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 17 analysts
BUY
Median target
$37.00
+49.2%
9 52.9%
Strong Buy
6 35.3%
Buy
2 11.8%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
10 analysts · 2026-10-02Mean target $38.38 +54.8%
← Below all targets
Current price $24.80
Low$26.00
Mean$38.38
High$55.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| ANRO | $568M | -8.1 | · | · | -46.1% | · |
| YARW | · | · | · | · | · | · |
| AMPH | $1.22B | 13.2 | -1.7% | 13.6% | 12.7% | 49.5% |
| PCRX | $1.06B | 161.8 | 3.6% | 0.97% | 0.97% | · |
| SPTX | · | · | · | · | · | · |
| ALMS | · | -3.4 | · | -1011.8% | -61.9% | · |
| APMD | · | · | · | · | · | · |
| SGP | · | · | · | · | 50.0% | · |
| LXRX | $421M | -8.2 | 60.2% | -101.1% | -39.7% | · |
| LLY | · | 46.8 | 44.7% | 31.7% | 101.2% | · |
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Source: SEC 10-Q filed Aug 12, 2026