CRVS — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $107,045,190 | 7,165,006 | 10.14% | Shares |
| BlackRock, Inc. | $106,653,837 | 7,138,811 | 10.10% | Shares |
| STATE STREET CORP | $66,842,920 | 4,474,091 | 6.33% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $49,193,087 | 3,292,710 | 4.66% | Shares |
| ADAMS STREET PARTNERS LLC | $48,937,703 | 3,275,616 | 4.63% | Shares |
| Vivo Capital, LLC | $41,918,891 | 2,805,816 | 3.97% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $40,810,581 | 2,731,632 | 3.87% | Shares |
| PERCEPTIVE ADVISORS LLC | $39,851,569 | 2,667,441 | 3.77% | Shares |
| Deep Track Capital, LP | $37,229,569 | 2,491,939 | 3.53% | Shares |
| BRAIDWELL LP | $31,766,892 | 2,126,298 | 3.01% | Shares |
| VANGUARD GROUP INC | $29,825,811 | 3,873,482 | 2.82% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $27,700,900 | 1,853,659 | 2.62% | Shares |
| Foresite Capital Management VI LLC | $27,358,621 | 1,831,233 | 2.59% | Shares |
| GOLDMAN SACHS GROUP INC | $23,550,700 | 1,576,352 | 2.23% | Shares |
| Hood River Capital Management LLC | $23,482,767 | 1,571,805 | 2.22% | Shares |
| MORGAN STANLEY | $20,090,356 | 1,344,736 | 1.90% | Shares |
| Boxer Capital Management, LLC | $16,434,000 | 1,100,000 | 1.56% | Shares |
| Catalio Capital Management, LP | $16,148,467 | 1,080,888 | 1.53% | Shares |
| MILLENNIUM MANAGEMENT LLC | $15,656,896 | 1,047,985 | 1.48% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12,172,365 | 814,750 | 1.15% | Shares |
| TWO SIGMA INVESTMENTS, LP | $11,731,008 | 785,208 | 1.11% | Shares |
| BANK OF AMERICA CORP /DE/ | $11,321,503 | 757,798 | 1.07% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11,205,000 | 750,000 | 1.06% | Shares |
| Eversept Partners, LP | $11,175,030 | 747,994 | 1.06% | Shares |
| EMERALD ADVISERS, LLC | $10,244,104 | 685,683 | 0.97% | Shares |
| DCF Advisers, LLC | $9,524,250 | 637,500 | 0.90% | Shares |
| Blue Owl Capital Holdings LP | $9,092,484 | 608,600 | 0.86% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $8,739,900 | 585,000 | 0.83% | Call option |
| NORTHERN TRUST CORP | $8,592,861 | 575,158 | 0.81% | Shares |
| EMERALD MUTUAL FUND ADVISERS TRUST | $7,864,252 | 526,389 | 0.74% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $7,776,688 | 520,528 | 0.74% | Shares |
| RA CAPITAL MANAGEMENT, L.P. | $6,723,000 | 450,000 | 0.64% | Shares |
| Nextech Invest Ltd. | $6,723,000 | 450,000 | 0.64% | Shares |
| CITADEL ADVISORS LLC | $6,675,192 | 446,800 | 0.63% | Call option |
| CITADEL ADVISORS LLC | $5,945,388 | 397,951 | 0.56% | Shares |
| UBS Group AG | $5,917,973 | 396,116 | 0.56% | Shares |
| BARCLAYS PLC | $4,717,289 | 315,749 | 0.45% | Shares |
| Jump Financial, LLC | $4,682,196 | 313,400 | 0.44% | Shares |
| Trexquant Investment LP | $4,427,424 | 296,347 | 0.42% | Shares |
| DIADEMA PARTNERS LP | $4,404,476 | 294,811 | 0.42% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,101,030 | 274,500 | 0.39% | Put option |
| Polymer Capital Management (HK) LTD | $3,939,110 | 263,662 | 0.37% | Shares |
| Brevan Howard Capital Management LP | $3,739,348 | 250,291 | 0.35% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $3,659,717 | 244,961 | 0.35% | Shares |
| Spruce Street Capital LP | $3,459,880 | 231,585 | 0.33% | Shares |
| SEB Asset Management AB | $3,388,938 | 226,837 | 0.32% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $3,298,169 | 220,761 | 0.31% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $3,253,185 | 217,750 | 0.31% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,109,298 | 208,119 | 0.29% | Shares |
| Bank of New York Mellon Corp | $3,026,973 | 202,609 | 0.29% | Shares |
| CITADEL ADVISORS LLC | $2,959,614 | 198,100 | 0.28% | Put option |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,848,177 | 190,641 | 0.27% | Shares |
| Caption Management, LLC | $2,838,600 | 190,000 | 0.27% | Call option |
| F/m Investments LLC | $2,497,445 | 167,165 | 0.24% | Shares |
| Nuveen, LLC | $2,417,606 | 161,821 | 0.23% | Shares |
| JANE STREET GROUP, LLC | $2,094,588 | 140,200 | 0.20% | Call option |
| JPMORGAN CHASE & CO | $2,055,957 | 141,986 | 0.19% | Shares |
| DIADEMA PARTNERS LP | $1,992,996 | 133,400 | 0.19% | Call option |
| D. E. Shaw & Co., Inc. | $1,989,664 | 133,177 | 0.19% | Shares |
| Swiss National Bank | $1,889,910 | 126,500 | 0.18% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $1,843,282 | 123,379 | 0.17% | Shares |
| Aquatic Capital Management LLC | $1,762,920 | 118,000 | 0.17% | Shares |
| ADAR1 Capital Management, LLC | $1,749,489 | 117,101 | 0.17% | Shares |
| CITIGROUP INC | $1,722,926 | 115,323 | 0.16% | Shares |
| Caption Management, LLC | $1,664,316 | 111,400 | 0.16% | Put option |
| MARSHALL WACE, LLP | $1,501,082 | 100,474 | 0.14% | Shares |
| RAYMOND JAMES FINANCIAL INC | $1,479,239 | 99,012 | 0.14% | Shares |
| SIMPLEX TRADING, LLC | $1,379,604 | 92,343 | 0.13% | Shares |
| ALLIANCEBERNSTEIN L.P. | $1,322,845 | 90,420 | 0.13% | Shares |
| RHUMBLINE ADVISERS | $1,285,128 | 86,020 | 0.12% | Shares |
| ALPS ADVISORS INC | $1,274,980 | 85,340 | 0.12% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1,238,631 | 82,907 | 0.12% | Shares |
| Seven Fleet Capital Management LP | $1,238,377 | 82,890 | 0.12% | Shares |
| TD Asset Management Inc | $1,233,984 | 82,596 | 0.12% | Shares |
| Rafferty Asset Management, LLC | $1,217,520 | 81,494 | 0.12% | Shares |
| SEI INVESTMENTS CO | $1,195,290 | 80,006 | 0.11% | Shares |
| Avidity Partners Management LP | $1,195,200 | 80,000 | 0.11% | Shares |
| Persistent Asset Partners Ltd | $1,117,452 | 74,796 | 0.11% | Shares |
| DEUTSCHE BANK AG\ | $1,113,463 | 74,529 | 0.11% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1,059,545 | 70,920 | 0.10% | Shares |
| Propel Bio Management, LLC | $1,051,477 | 70,380 | 0.10% | Shares |
| TOWERVIEW LLC | $1,045,800 | 70,000 | 0.10% | Shares |
| Caption Management, LLC | $956,668 | 64,034 | 0.09% | Shares |
| JACKSON SQUARE CAPITAL, LLC | $952,769 | 63,773 | 0.09% | Shares |
| WELLS FARGO & COMPANY/MN | $922,770 | 61,765 | 0.09% | Shares |
| TUDOR INVESTMENT CORP ET AL | $902,376 | 60,400 | 0.09% | Call option |
| Ancora Advisors LLC | $847,442 | 56,723 | 0.08% | Shares |
| FRANKLIN RESOURCES INC | $847,144 | 56,703 | 0.08% | Shares |
| SEVEN GRAND MANAGERS, LLC | $747,000 | 50,000 | 0.07% | Shares |
| GROUP ONE TRADING LLC | $721,482 | 48,292 | 0.07% | Shares |
| Vanguard Global Advisers, LLC | $712,459 | 47,688 | 0.07% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $660,632 | 44,219 | 0.06% | Shares |
| Squarepoint Ops LLC | $660,423 | 44,205 | 0.06% | Shares |
| Y-Intercept (Hong Kong) Ltd | $653,909 | 43,769 | 0.06% | Shares |
| Creative Planning | $630,080 | 42,174 | 0.06% | Shares |
| Invesco Ltd. | $623,028 | 41,702 | 0.06% | Shares |
| Legal & General Group Plc | $622,954 | 41,697 | 0.06% | Shares |
| TEMA ETFS LLC | $613,675 | 79,698 | 0.06% | Shares |
| PROFUND ADVISORS LLC | $613,197 | 41,044 | 0.06% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $602,897 | 40,646 | 0.06% | Shares |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $595,031 | 39,828 | 0.06% | Shares |
| MetLife Investment Management, LLC | $592,341 | 39,648 | 0.06% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $559,159 | 37,427 | 0.05% | Shares |
| AVITY INVESTMENT MANAGEMENT INC. | $555,021 | 37,150 | 0.05% | Shares |
| Engineers Gate Manager LP | $538,124 | 36,019 | 0.05% | Shares |
| OPTIMIZE FINANCIAL INC. | $417,767 | 27,963 | 0.04% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $414,719 | 27,759 | 0.04% | Shares |
| Virtus Investment Advisers, LLC | $409,759 | 27,427 | 0.04% | Shares |
| ACT CAPITAL MANAGEMENT, LLC | $403,380 | 27,000 | 0.04% | Shares |
| Russell Investments Group, Ltd. | $378,535 | 25,337 | 0.04% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $374,994 | 25,100 | 0.04% | Shares |
| SIMON QUICK ADVISORS, LLC | $373,500 | 25,000 | 0.04% | Shares |
| PEAK6 LLC | $352,584 | 23,600 | 0.03% | Call option |
| WINTON GROUP Ltd | $346,608 | 23,200 | 0.03% | Shares |
| TUDOR INVESTMENT CORP ET AL | $328,560 | 21,992 | 0.03% | Shares |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | $325,259 | 21,771 | 0.03% | Shares |
| China Universal Asset Management Co., Ltd. | $319,462 | 21,383 | 0.03% | Shares |
| State of New Jersey Common Pension Fund D | $304,313 | 20,369 | 0.03% | Shares |
| JANE STREET GROUP, LLC | $301,788 | 20,200 | 0.03% | Put option |
| AlphaQuest LLC | $276,984 | 35,972 | 0.03% | Shares |
| Persistent Asset Partners Ltd | $274,383 | 340 | 0.03% | Call option |
| FOX RUN MANAGEMENT, L.L.C. | $269,742 | 18,055 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $269,159 | 18,016 | 0.03% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $259,687 | 17,382 | 0.02% | Shares |
| Lido Advisors, LLC | $242,700 | 16,245 | 0.02% | Shares |
| Vanguard Investments Australia, Ltd. | $241,908 | 16,192 | 0.02% | Shares |
| Pictet Asset Management Holding SA | $233,497 | 15,629 | 0.02% | Shares |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $225,773 | 15,112 | 0.02% | Shares |
| Sowell Financial Services LLC | $223,727 | 14,975 | 0.02% | Shares |
| KLP KAPITALFORVALTNING AS | $213,642 | 14,300 | 0.02% | Shares |
| PEAK6 LLC | $212,522 | 14,225 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $210,968 | 14,121 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $191,008 | 12,785 | 0.02% | Shares |
| Jain Global LLC | $187,124 | 12,525 | 0.02% | Shares |
| ProShare Advisors LLC | $173,633 | 11,622 | 0.02% | Shares |
| E Fund Management Co., Ltd. | $171,676 | 11,491 | 0.02% | Shares |
| SBI Securities Co., Ltd. | $169,778 | 11,364 | 0.02% | Shares |
| PRUDENTIAL FINANCIAL INC | $164,265 | 10,995 | 0.02% | Shares |
| WHITTIER TRUST CO OF NEVADA INC | $159,426 | 10,200 | 0.02% | Shares |
| Mengis Capital Management, Inc. | $156,123 | 10,450 | 0.01% | Shares |
| Truvestments Capital LLC | $152,313 | 10,195 | 0.01% | Shares |
| OneDigital Investment Advisors LLC | $149,414 | 10,001 | 0.01% | Shares |
| Ghisallo Capital Management LLC | $149,400 | 10,000 | 0.01% | Shares |
| TWO SIGMA ADVISERS, LP | $145,530 | 18,900 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $128,000 | 8,593 | 0.01% | Shares |
| Masso Torrence Wealth Management Inc. | $125,290 | 17,000 | 0.01% | Shares |
| ROTHSCHILD INVESTMENT LLC | $105,357 | 7,052 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $97,439 | 6,522 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $91,806 | 6,145 | 0.01% | Shares |
| MEEDER ASSET MANAGEMENT INC | $90,462 | 6,055 | 0.01% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $89,477 | 6,116 | 0.01% | Shares |
| State of Wyoming | $70,741 | 4,735 | 0.01% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $56,611 | 3,789,126 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $56,189 | 3,761 | 0.01% | Shares |
| Mitsubishi UFJ Asset Management Co., Ltd. | $47,808 | 3,200 | 0.00% | Shares |
| FMR LLC | $35,199 | 2,356 | 0.00% | Shares |
| Global Retirement Partners, LLC | $29,910 | 2,002 | 0.00% | Shares |
| Western Pacific Wealth Management, LP | $29,880 | 2,000 | 0.00% | Shares |
| Northwest Capital Management Inc | $26,160 | 3,397 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $26,145 | 1,750 | 0.00% | Shares |
| CWM, LLC | $18,097 | 1,237 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $10,876 | 728 | 0.00% | Shares |
| GAMMA Investing LLC | $10,144 | 679 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $6,364 | 426 | 0.00% | Shares |
| Allworth Financial LP | $5,663 | 379 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $4,049 | 271 | 0.00% | Shares |
| Sterling Capital Management LLC | $3,556 | 238 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $3,093 | 207 | 0.00% | Shares |
| Physician Wealth Advisors, Inc. | $2,645 | 177 | 0.00% | Shares |
| US BANCORP \DE\ | $2,480 | 166 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $2,390 | 160 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $1,718 | 115 | 0.00% | Shares |
| EASTERN BANK | $1,374 | 92 | 0.00% | Shares |
| SIGNATUREFD, LLC | $1,135 | 76 | 0.00% | Shares |
| KELLEHER FINANCIAL ADVISORS | $1,121 | 75 | 0.00% | Shares |
| Arax Advisory Partners | $1,121 | 75 | 0.00% | Shares |
| Larson Financial Group LLC | $1,031 | 69 | 0.00% | Shares |
| Hikari Power Ltd | $746 | 49,959 | 0.00% | Shares |
| Quarry LP | $627 | 42 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $553 | 37 | 0.00% | Shares |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $500 | 33,458 | 0.00% | Shares |
| SG Americas Securities, LLC | $463 | 30,994 | 0.00% | Shares |
| Versant Capital Management, Inc | $323 | 28 | 0.00% | Shares |
| Stone House Investment Management, LLC | $105 | 7 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $30 | 2 | 0.00% | Shares |
| Pacer Advisors, Inc. | $20 | 1,361 | 0.00% | Shares |
| Covestor Ltd | $0 | 28 | 0.00% | Shares |