PLRX — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | $7,001,038 | 6,141,261 | 12.30% | Shares |
| ADAR1 Capital Management, LLC | $6,281,085 | 5,509,724 | 11.04% | Shares |
| VANGUARD GROUP INC | $3,438,255 | 2,818,241 | 6.04% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $2,782,000 | 2,440,351 | 4.89% | Shares |
| TWO SIGMA INVESTMENTS, LP | $2,579,628 | 2,262,832 | 4.53% | Shares |
| CITADEL ADVISORS LLC | $2,442,138 | 2,142,226 | 4.29% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $2,336,856 | 2,049,874 | 4.11% | Shares |
| Monaco Asset Management SAM | $2,210,172 | 1,938,747 | 3.88% | Shares |
| Lynx1 Capital Management LP | $2,049,800 | 1,798,070 | 3.60% | Shares |
| BML Capital Management, LLC | $1,762,596 | 1,546,137 | 3.10% | Shares |
| Prosight Management, LP | $1,562,066 | 1,370,233 | 2.74% | Shares |
| TWO SIGMA ADVISERS, LP | $1,519,632 | 1,245,600 | 2.67% | Shares |
| Peapod Lane Capital LLC | $1,492,275 | 1,309,013 | 2.62% | Shares |
| Woodline Partners LP | $1,478,049 | 1,296,534 | 2.60% | Shares |
| BlackRock, Inc. | $1,312,384 | 1,151,214 | 2.31% | Shares |
| Ikarian Capital, LLC | $1,140,000 | 1,000,000 | 2.00% | Shares |
| Eversept Partners, LP | $1,016,224 | 891,425 | 1.79% | Shares |
| MARSHALL WACE, LLP | $952,041 | 835,124 | 1.67% | Shares |
| Redmile Group, LLC | $880,224 | 772,126 | 1.55% | Shares |
| JPMORGAN CHASE & CO | $783,894 | 681,647 | 1.38% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $733,157 | 643,120 | 1.29% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $659,954 | 578,577 | 1.16% | Shares |
| UBS Group AG | $651,806 | 571,760 | 1.15% | Shares |
| MILLENNIUM MANAGEMENT LLC | $637,770 | 559,447 | 1.12% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $631,138 | 553,630 | 1.11% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $611,132 | 536,081 | 1.07% | Shares |
| DAFNA Capital Management LLC | $555,180 | 487,000 | 0.98% | Shares |
| XTX Topco Ltd | $502,562 | 440,844 | 0.88% | Shares |
| Laurion Capital Management LP | $470,587 | 412,796 | 0.83% | Shares |
| TORNO CAPITAL, LLC | $400,647 | 351,445 | 0.70% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $389,596 | 341,751 | 0.68% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $345,420 | 303,000 | 0.61% | Shares |
| MORGAN STANLEY | $340,833 | 298,976 | 0.60% | Shares |
| SEI INVESTMENTS CO | $338,909 | 297,291 | 0.60% | Shares |
| Verdad Advisers, LP | $320,731 | 281,343 | 0.56% | Shares |
| ArrowMark Colorado Holdings LLC | $320,555 | 281,189 | 0.56% | Shares |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $313,500 | 275,000 | 0.55% | Shares |
| STATE STREET CORP | $288,897 | 253,418 | 0.51% | Shares |
| Stonepine Capital Management, LLC | $262,813 | 230,538 | 0.46% | Shares |
| Rangeley Capital, LLC | $256,500 | 225,000 | 0.45% | Shares |
| GOLDMAN SACHS GROUP INC | $237,787 | 208,585 | 0.42% | Shares |
| Congress Wealth Management LLC / DE / | $231,907 | 199,920 | 0.41% | Shares |
| Marquette Asset Management, LLC | $198,930 | 174,500 | 0.35% | Shares |
| HighMark Wealth Management LLC | $189,495 | 166,224 | 0.33% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $175,232 | 153,712 | 0.31% | Shares |
| JANE STREET GROUP, LLC | $148,144 | 129,951 | 0.26% | Shares |
| NORTHERN TRUST CORP | $142,568 | 125,060 | 0.25% | Shares |
| ALGERT GLOBAL LLC | $140,678 | 123,402 | 0.25% | Shares |
| OSAIC HOLDINGS, INC. | $131,013 | 114,924 | 0.23% | Shares |
| Invesco Ltd. | $119,333 | 104,678 | 0.21% | Shares |
| Bond & Devick Financial Network, Inc. | $114,182 | 100,160 | 0.20% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $113,779 | 99,773 | 0.20% | Shares |
| KOTLER KEVIN | $113,460 | 93,000 | 0.20% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $93,366 | 81,900 | 0.16% | Put option |
| Cubist Systematic Strategies, LLC | $80,463 | 54,367 | 0.14% | Shares |
| JANE STREET GROUP, LLC | $70,566 | 61,900 | 0.12% | Call option |
| AMERIPRISE FINANCIAL INC | $62,847 | 55,129 | 0.11% | Shares |
| Squarepoint Ops LLC | $46,528 | 40,814 | 0.08% | Shares |
| Headlands Technologies LLC | $38,404 | 33,688 | 0.07% | Shares |
| Quadrature Capital Ltd | $37,939 | 33,280 | 0.07% | Shares |
| TUDOR INVESTMENT CORP ET AL | $33,891 | 29,729 | 0.06% | Shares |
| FEDERATED HERMES, INC. | $33,123 | 29,055 | 0.06% | Shares |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $32,490 | 28,500 | 0.06% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $32,419 | 21,905 | 0.06% | Shares |
| Spark Investment Management LLC | $25,764 | 22,600 | 0.05% | Shares |
| Blackstone Inc. | $25,315 | 22,206 | 0.04% | Shares |
| Point72 Asset Management, L.P. | $22,883 | 20,073 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $22,238 | 19,507 | 0.04% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $20,594 | 18,065 | 0.04% | Shares |
| Bank of New York Mellon Corp | $18,277 | 16,032 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $17,647 | 15,480 | 0.03% | Shares |
| NewEdge Advisors, LLC | $17,100 | 15,000 | 0.03% | Shares |
| AlphaQuest LLC | $14,294 | 11,716 | 0.03% | Shares |
| JANE STREET GROUP, LLC | $13,794 | 12,100 | 0.02% | Put option |
| Fiduciary Trust Co | $13,247 | 11,620 | 0.02% | Shares |
| Qube Research & Technologies Ltd | $11,438 | 10,033 | 0.02% | Shares |
| SIMPLEX TRADING, LLC | $5,614 | 4,925 | 0.01% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $2,747 | 2,416,508 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $2,000 | 995 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $752 | 660 | 0.00% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $749 | 657 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $672 | 590 | 0.00% | Shares |
| BESSEMER GROUP INC | $606 | 532,079 | 0.00% | Shares |
| BARCLAYS PLC | $486 | 426 | 0.00% | Shares |
| FMR LLC | $478 | 419 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $342 | 300 | 0.00% | Shares |
| CWM, LLC | $267 | 212 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $185 | 162,206 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $166 | 112 | 0.00% | Shares |
| Truvestments Capital LLC | $57 | 50 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $57 | 50 | 0.00% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $41 | 36 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $9 | 8 | 0.00% | Shares |
| COMERICA BANK | $7 | 6 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $6 | 5 | 0.00% | Shares |
| IFG Advisory, LLC | $5 | 4 | 0.00% | Shares |
| Global Retirement Partners, LLC | $5 | 4 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $5 | 4 | 0.00% | Shares |
| Capital Advisors, Ltd. LLC | $0 | 31 | 0.00% | Shares |