your badges 52W Range $154–$393 41% of range Analyst Rating BUY 25 analysts Price Target $650 +157% upside P/E -20.8 ROE -47.3% Net Profit Margin ·

PRAX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $252.96
Market Cap (MRQ) $7.06B
P/E -20.8
EPS $-13.48
Revenue $0
ROE -47.3%
52W Range $154–$393

PRAX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 1
Ex-date Split Type
Nov. 29, 2023 1-for-15 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$0
2022-12-31 → 2025-12-31
EPS$-13.48
2020-12-31 → 2025-12-31
Free Cash Flow$-249M
2020-12-31 → 2025-12-31
Net margin·
2023-12-31 → 2024-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend PRAX 5Y avg Peer Median Verdict
P/E -20.85Y avg ≈-21.2 ≈-21.2 · ·
P/B (MRQ) 5.35Y avg ≈18.2 ≈18.2 10.8 Undervalued
Price / FCF (TTM) -23.15Y avg ≈-31.8 ≈-31.8 · ·
Price / Cash Flow (TTM) -23.15Y avg ≈-32.0 ≈-32.0 · ·
Price / Tangible Book (MRQ) 5.35Y avg ≈18.2 ≈18.2 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 4.9%
Next Report Nov 11, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 3, 2026 $-2.87 $-3.73 23.1%
March 31, 2026 May 13, 2026 $-3.20 $-3.58 10.7%
Dec. 31, 2025 $-3.50 $-3.16 -10.7%
Sept. 30, 2025 $-3.36 $-3.51 4.3%
June 30, 2025 $-3.31 $-3.40 2.6%
March 31, 2025 $-3.29 $-3.27 -0.77%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 2025202420232022
Revenue $0$9M$2M$0
R&D Expense $267M$152M$87M$155M
SG&A Expense $59M$56M$42M$60M
Operating Expenses $326M$209M$129M$215M
Operating Income $-326M$-200M$-126M$-215M
Other Non-op $23M$17M$3M$957.0K
Pretax Income $-303M$-183M$-123M·
Income Tax $471.0K···
Net Income $-303M$-183M$-123M$-214M
EPS (Basic) $-13.48$-10.21$-18.69$-69.65
EPS (Diluted) $-13.48$-10.21$-18.69$-69.65
Shares (Basic) 22,504,67617,906,7946,594,3163,073,100
Shares (Diluted) 22,504,67617,906,7946,594,3163,073,100
EBITDA $-326M$-200M$-126M$-215M
Balance Sheet 22
Metric Trend 2025202420232022
Cash & Equivalents $357M$215M$81M$62M
Short-term Investments $242M$177M··
Prepaid Expense $12M$12M$4M$10M
Current Assets $611M$404M$85M$111M
PP&E (Net) $147.0K$230.0K$588.0K$971.0K
PP&E (Gross) $2M$2M$2M$2M
Accum. Depreciation $2M$1M$1M$572.0K
Intangibles $0···
Other Non-current Assets $0$416.0K$416.0K$416.0K
Total Assets $938M$483M$88M$115M
Accounts Payable $25M$13M$6M$15M
Accrued Liabilities $35M$24M$7M$16M
Current Liabilities $60M$38M$16M$34M
Capital Leases $0$110.0K$1M$2M
Total Liabilities $60M$38M$18M$39M
Common Stock $15.0K$14.0K$13.0K$5.0K
Paid-in Capital $2.02B$1.28B$724M$607M
Retained Earnings $-1.14B$-837M$-654M$-531M
AOCI $563.0K$654.0K$0$-173.0K
Stockholders' Equity $878M$445M$70M$76M
Liabilities + Equity $938M$483M$88M$115M
Shares Outstanding 25,195,09219,422,3588,791,8773,292,163
Cash Flow 10
Metric Trend 2025202420232022
Stock-based Comp $34M$41M$25M$29M
Operating Cash Flow $-249M$-132M$-111M$-185M
CapEx $56.0K$0$50.0K$444.0K
Investing Cash Flow $-311M$-248M$39M$97M
Stock Issued ···$0
Net Stock Activity ···$0
Financing Cash Flow $702M$514M$92M$10M
Net Change in Cash $142M$134M$20M$-78M
Taxes Paid $224.0K···
Free Cash Flow $-249M$-132M$-111M$-185M
Profitability 6
Metric Trend 2025202420232022
Operating Margin ·-2340.3%-5164.4%·
Net Margin ·-2137.5%-5037.9%·
EBITDA Margin ·-2340.3%-5164.4%·
ROA -42.7%-64.0%-121.4%-105.0%
ROE -47.3%-44.1%-157.6%-236.2%
ROIC -37.2%···
Liquidity & Solvency 2
Metric Trend 2025202420232022
Current Ratio 10.210.85.43.2
Quick Ratio 10.05.75.21.8
Efficiency 1
Metric Trend 2025202420232022
Asset Turnover 0.00.00.0·
Per Share 5
Metric Trend 2025202420232022
Book Value / Share $34.85$22.93$7.92$1.54
Revenue / Share $0.00$0.48$0.37·
Cash Flow / Share $-11.07$-7.36$-16.85$-4.01
Cash / Share $14.18$11.09$9.25$1.25
EPS (TTM) $-13.48$-10.21$-18.69$-69.65
Growth Rates 1
Metric Trend 2025202420232022
Revenue YoY ·249.5%··
Valuation (TTM) 10
Metric Trend 2025202420232022
Revenue TTM $0$9M$2M$0
Net Income TTM $-303M$-183M$-123M$-214M
Market Cap $7.43B$1.49B$196M$1.76B
P/E -21.9-7.5-1.2-0.5
P/S ·174.880.1·
P/B 8.53.42.823.2
P / Tangible Book 8.53.42.823.2
P / Cash Flow -29.8-11.3-1.8-9.5
P / FCF -29.8-11.3-1.8-9.5
Earnings Yield -4.6%-13.3%-83.9%-195.1%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0 $9M $2M $0 ·
Operating Margin % · -2340.3% -5164.4% · ·
Net Income $-303M $-183M $-123M $-214M $-167M
Diluted EPS $-13.48 $-10.21 $-18.69 $-69.65 $-3.94

Institutional owners (13F) 340 filers · $11.6B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 340
Value held $11.6B
New positions 62
Exited positions 39
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
62 (-24 vs prior Q) 39 (+8 vs prior Q) 124 (+6 vs prior Q) 101 (+25 vs prior Q) -1.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
JANUS HENDERSON GROUP PLC $1,113,513,848 3,458,863 9.56% Shares
FMR LLC $775,677,279 2,316,907 6.66% Shares
BlackRock, Inc. $767,534,532 2,292,585 6.59% Shares
PERCEPTIVE ADVISORS LLC $681,627,753 2,035,986 5.85% Shares
BAKER BROS. ADVISORS LP $586,953,158 1,753,198 5.04% Shares
Orbis Allan Gray Ltd $512,157,724 1,529,788 4.40% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $447,006,586 1,335,185 3.84% Shares
VANGUARD GROUP INC $430,595,392 1,460,933 3.70% Shares
VANGUARD CAPITAL MANAGEMENT LLC $413,565,752 1,235,299 3.55% Shares
STATE STREET CORP $343,656,004 1,026,443 2.95% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $339,972,549 1,015,480 2.92% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $322,520,281 963,351 2.77% Shares
Driehaus Capital Management LLC $321,079,680 959,048 2.76% Shares
MORGAN STANLEY $285,948,294 854,112 2.46% Shares
GEODE CAPITAL MANAGEMENT, LLC $250,477,901 748,039 2.15% Shares
Cormorant Asset Management, LP $214,265,600 640,000 1.84% Shares
GOLDMAN SACHS GROUP INC $183,742,796 548,830 1.58% Shares
BANK OF AMERICA CORP /DE/ $183,106,695 546,930 1.57% Shares
Invesco Ltd. $179,965,694 537,548 1.55% Shares
Hood River Capital Management LLC $142,341,660 425,167 1.22% Shares
NORGES BANK $116,161,752 346,969 1.00% Shares
FRANKLIN RESOURCES INC $109,517,858 327,124 0.94% Shares
Pictet Asset Management Holding SA $98,035,469 291,689 0.84% Shares
Polar Capital Holdings Plc $93,450,267 279,131 0.80% Shares
Vivo Capital, LLC $90,766,926 271,116 0.78% Shares
Logos Global Management LP $87,045,400 260,000 0.75% Shares
NORTHERN TRUST CORP $80,646,559 240,887 0.69% Shares
AMERICAN CENTURY COMPANIES INC $79,451,539 237,315 0.68% Shares
ORBIMED ADVISORS LLC $77,035,179 230,100 0.66% Shares
Caption Management, LLC $75,260,792 224,800 0.65% Put option
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $73,656,478 220,008 0.63% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $73,284,861 218,898 0.63% Shares
Verition Fund Management LLC $67,326,269 201,100 0.58% Put option
Woodline Partners LP $66,962,352 200,013 0.57% Shares
BNP PARIBAS FINANCIAL MARKETS $63,077,449 188,409 0.54% Shares
VANGUARD FIDUCIARY TRUST CO $62,994,421 188,161 0.54% Shares
Affinity Asset Advisors, LLC $61,936,150 185,000 0.53% Shares
Soleus Capital Management, L.P. $59,430,916 177,517 0.51% Shares
Aberdeen Group plc $55,708,721 166,399 0.48% Shares
Qube Research & Technologies Ltd $51,047,105 152,475 0.44% Shares
MARSHALL WACE, LLP $45,868,907 137,008 0.39% Shares
UBS Group AG $43,872,891 131,046 0.38% Shares
WELLINGTON MANAGEMENT GROUP LLP $42,139,013 125,867 0.36% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $41,882,229 125,100 0.36% Put option
VOYA INVESTMENT MANAGEMENT LLC $40,920,377 122,227 0.35% Shares
683 Capital Management, LLC $36,960,816 110,400 0.32% Put option
Nuveen, LLC $36,168,033 108,032 0.31% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $35,959,459 107,409 0.31% Shares
Nantahala Capital Management, LLC $33,479,000 100,000 0.29% Put option
MetLife Investment Management, LLC $30,312,891 90,543 0.26% Shares

Show all 340 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Velan Capital Master Fund LP, Velan Capital Holdings LLC, Velan Capital Investment Management LP, Velan Capital Management LLC, Adam Morgan, Balaji Venkataraman ×2 filings June 28, 2023 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 17 insiders · 7 officers · 10 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Marcio Souza Chief Executive Officer July 8, 2026 G 0 0 0 $0
Timothy Edwin Kelly Chief Financial Officer May 14, 2026 A 31,167 0 0 $0
Megan Sniecinski Chief Operating Officer May 14, 2026 A 28,664 0 0 $0
Alex Nemiroff General Counsel and Secretary May 14, 2026 A 26,011 0 4 $-4,852,208
Lauren Mastrocola Principal Accounting Officer May 14, 2026 A 13,573 0 2 $-2,612,265
Nicole Sweeny Chief Commercial Officer Feb. 12, 2023 F 38,619 0 0 $0
Bernard Ravina Chief Medical Officer June 22, 2022 A 99,476 0 0 $0
Jill Desimone Director June 24, 2026 M 2,337 0 12 $-3,611,315
Merit Ester Cudkowicz Director June 10, 2026 A 1,371 0 0 $0
Jeffrey Chodakewitz Director June 10, 2026 A 1,371 0 0 $0
Stuart A Arbuckle Director June 10, 2026 A 2,537 0 0 $0
Gregory Norden Director June 10, 2026 A 1,559 0 0 $0
William D Young Director June 10, 2026 A 3,269 0 0 $0
Dean J Mitchell Director June 10, 2026 A 18,622 0 0 $0
Jeffrey B Kindler Director June 10, 2026 A 2,537 0 0 $0
Stefan Vitorovic Director May 26, 2022 A 2,939,329 0 0 $0
Novo Holdings A/S 10% owner Oct. 20, 2020 C 2,442,080 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 47 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IBRN · iShares Trust 5.24% 1,157 SH Sept. 11, 2026 Daily
MMSC · First Trust Exchange-Traded Fund VI… 1.07% 1,575 NS Aug. 31, 2026 N-PORT
GURU · Global X Funds 1.05% 2,082 NS July 31, 2026 N-PORT
MEDI · Harbor ETF Trust 0.91% 1,221 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.87% 14,020 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.77% 1,166 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.65% 199,589 SH Sept. 11, 2026 Daily
JSML · Janus Detroit Street Trust 0.63% 7,368 NS July 31, 2026 N-PORT
IWO · iShares Trust 0.56% 236,493 SH Sept. 11, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.50% 26,912 SH Aug. 19, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.47% 2,083 SH Oct. 23, 2026 Daily
ESSC · Strategy Shares 0.40% 473 NS July 31, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.29% 3,142 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.28% 642,516 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.26% 144,661 SH Aug. 19, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.26% 5,865 NS July 31, 2026 N-PORT
RSSL · Global X Funds 0.25% 12,034 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.25% 192 NS July 31, 2026 N-PORT
ISCG · iShares Trust 0.24% 6,830 SH Sept. 11, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.21% 10,155 NS July 31, 2026 N-PORT
VBR · VANGUARD INDEX FUNDS 0.20% 405,873 SH Aug. 19, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.20% 11,745 SH Aug. 19, 2026 Daily
BKMC · BNY Mellon ETF Trust 0.20% 4,125 NS July 31, 2026 N-PORT
FNY · First Trust Exchange-Traded AlphaDE… 0.15% 2,741 NS July 31, 2026 N-PORT
ESML · iShares Trust 0.12% 9,983 SH Sept. 11, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.11% 639,384 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.11% 69,046 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.10% 10,917 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.10% 300,792 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.07% 1,471 SH Sept. 11, 2026 Daily
FBCG · FIDELITY COVINGTON TRUST 0.07% 14,899 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.04% 823 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.04% 4,150 SH Oct. 23, 2026 Daily
DXUV · Dimensional ETF Trust 0.03% 581 NS July 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.03% 12,964 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.02% 1,134 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.01% 33,950 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.01% 6,950 SH Sept. 11, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.01% 885,574 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.01% 20,537 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 2,065 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.01% 5,551 SH Aug. 19, 2026 Daily
DFUS · Dimensional ETF Trust 0.01% 5,730 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 4,257 NS July 31, 2026 N-PORT
CLSE · Trust for Professional Managers -0.20% -5,034 NS Aug. 31, 2026 N-PORT
ISCB · iShares Trust · 972 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 3,009 SH Sept. 11, 2026 Daily

PRAX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 25 analysts BUY
Median target $582.00 +130.1%
9 36.0% Strong Buy
13 52.0% Buy
2 8.0% Hold
0 0.0% Sell
1 4.0% Strong Sell

12-Month Price Target

21 analysts · 2026-10-24

Mean target $650.00 +157.0%

Now Current price $252.96
Low$188.00 Mean$650.00 High$1201.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PRAX $7.43B -21.9 249.5% · -47.3% ·
ARWR $4.68B -3449.0 23258.2% -0.20% -0.50% ·
IONS $12.92B -33.2 · · -68.1% ·
IOVA $1.12B -2.5 60.6% -148.4% -56.0% ·
RYTM $7.19B -34.4 45.8% -103.6% -309.1% ·
GRAL $3.45B -7.7 17.2% -277.5% -16.7% ·
IMVT $5.07B -9.0 229.2% · -73.7% ·

Latest News Recent headlines mentioning this company

23
Praxis Precision Medicines (PRAX) Reports $926M 2025 Cash Balance, Extended Runway Yahoo Finance · This $64 Million Biotech Exit Seemingly Missed a 77% One-Day Surge on Gilead Takeover Deal Yahoo Finance ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 6, 2026