ALMS — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| AyurMaya Capital Management Company, LP | $426,031,355 | 15,139,707 | 13.18% | Shares |
| BlackRock, Inc. | $231,258,771 | 8,218,151 | 7.16% | Shares |
| FMR LLC | $190,484,444 | 6,769,170 | 5.89% | Shares |
| Deep Track Capital, LP | $178,648,422 | 6,348,558 | 5.53% | Shares |
| SAMSARA BIOCAPITAL, LLC | $178,554,463 | 6,345,219 | 5.53% | Shares |
| Foresite Capital Management V, LLC | $165,941,439 | 5,896,995 | 5.14% | Shares |
| venBio Partners LLC | $127,429,401 | 4,528,408 | 3.94% | Shares |
| Foresite Capital Management VI LLC | $119,529,434 | 4,247,670 | 3.70% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $118,629,882 | 4,215,703 | 3.67% | Shares |
| Nextech Invest Ltd. | $99,643,684 | 3,540,998 | 3.08% | Shares |
| Cormorant Asset Management, LP | $92,456,671 | 3,285,596 | 2.86% | Shares |
| Saturn V Capital Management LP | $82,040,566 | 2,915,443 | 2.54% | Shares |
| Octagon Capital Advisors LP | $79,655,898 | 2,830,700 | 2.47% | Shares |
| STATE STREET CORP | $61,549,665 | 2,187,266 | 1.90% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $61,033,791 | 2,168,517 | 1.89% | Shares |
| MPM BIOIMPACT LLC | $56,815,223 | 2,019,020 | 1.76% | Shares |
| BAKER BROS. ADVISORS LP | $56,631,750 | 2,012,500 | 1.75% | Shares |
| SR One Capital Management, LP | $55,151,473 | 1,959,896 | 1.71% | Shares |
| JANUS HENDERSON GROUP PLC | $46,790,086 | 2,124,408 | 1.45% | Shares |
| VANGUARD GROUP INC | $40,048,110 | 4,103,290 | 1.24% | Shares |
| Invesco Ltd. | $33,022,796 | 1,173,518 | 1.02% | Shares |
| NOVO HOLDINGS A/S | $30,954,000 | 1,100,000 | 0.96% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $30,055,208 | 1,068,060 | 0.93% | Shares |
| D. E. Shaw & Co., Inc. | $27,246,105 | 968,234 | 0.84% | Shares |
| UBS Group AG | $26,783,540 | 951,796 | 0.83% | Shares |
| JPMORGAN CHASE & CO | $26,407,356 | 969,617 | 0.82% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $25,922,878 | 921,211 | 0.80% | Shares |
| Ikarian Capital, LLC | $24,497,220 | 870,548 | 0.76% | Shares |
| GREAT POINT PARTNERS LLC | $24,089,557 | 856,061 | 0.75% | Shares |
| GOLDMAN SACHS GROUP INC | $23,409,581 | 831,897 | 0.72% | Shares |
| NORTHERN TRUST CORP | $20,369,111 | 723,849 | 0.63% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $19,701,771 | 700,134 | 0.61% | Shares |
| Integral Health Asset Management, LLC | $19,698,000 | 700,000 | 0.61% | Shares |
| MILLENNIUM MANAGEMENT LLC | $18,576,396 | 660,142 | 0.57% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $17,221,961 | 612,010 | 0.53% | Shares |
| Opaleye Management Inc. | $15,477,000 | 550,000 | 0.48% | Shares |
| ORBIMED ADVISORS LLC | $15,425,307 | 548,163 | 0.48% | Shares |
| ROYCE & ASSOCIATES LP | $14,782,026 | 525,303 | 0.46% | Shares |
| Woodline Partners LP | $13,677,503 | 486,052 | 0.42% | Shares |
| Spruce Street Capital LP | $11,047,032 | 392,574 | 0.34% | Shares |
| Trium Capital LLP | $10,982,142 | 390,268 | 0.34% | Shares |
| CITIGROUP INC | $10,845,156 | 385,400 | 0.34% | Shares |
| TWO SIGMA INVESTMENTS, LP | $10,583,989 | 376,119 | 0.33% | Shares |
| MARSHALL WACE, LLP | $10,355,915 | 368,014 | 0.32% | Shares |
| Ikarian Capital, LLC | $10,026,282 | 356,300 | 0.31% | Call option |
| MORGAN STANLEY | $9,037,528 | 321,163 | 0.28% | Shares |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $9,029,029 | 320,861 | 0.28% | Shares |
| Weiss Asset Management LP | $8,761,980 | 311,371 | 0.27% | Shares |
| Artia Global Partners LP | $7,838,284 | 278,546 | 0.24% | Shares |
| BARCLAYS PLC | $7,702,368 | 273,716 | 0.24% | Shares |
| Yu Fan | $7,110,190 | 252,672 | 0.22% | Shares |
| Nuveen, LLC | $6,862,558 | 243,872 | 0.21% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $6,825,019 | 242,538 | 0.21% | Shares |
| Omega Fund Management, LLC | $6,788,916 | 241,255 | 0.21% | Shares |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $6,427,865 | 236,841 | 0.20% | Shares |
| Bank of New York Mellon Corp | $6,377,030 | 226,618 | 0.20% | Shares |
| TOWERVIEW LLC | $6,255,353 | 222,294 | 0.19% | Shares |
| BANK OF AMERICA CORP /DE/ | $5,847,183 | 207,789 | 0.18% | Shares |
| Exome Asset Management LLC | $5,752,323 | 204,418 | 0.18% | Shares |
| DIADEMA PARTNERS LP | $5,628,000 | 200,000 | 0.17% | Call option |
| HighVista Strategies LLC | $5,627,100 | 199,968 | 0.17% | Shares |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | $5,583,008 | 1,399,250 | 0.17% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $5,059,628 | 179,802 | 0.16% | Shares |
| WELLS FARGO & COMPANY/MN | $4,922,024 | 174,912 | 0.15% | Shares |
| Susquehanna Portfolio Strategies, LLC | $4,862,001 | 172,779 | 0.15% | Shares |
| PRUDENTIAL FINANCIAL INC | $4,575,086 | 162,583 | 0.14% | Shares |
| Russell Investments Group, Ltd. | $4,330,918 | 153,906 | 0.13% | Shares |
| Ensign Peak Advisors, Inc | $4,135,736 | 146,970 | 0.13% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $4,120,736 | 146,437 | 0.13% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $3,895,082 | 138,418 | 0.12% | Shares |
| MOORE CAPITAL MANAGEMENT, LP | $3,849,636 | 136,803 | 0.12% | Shares |
| Swiss National Bank | $3,824,226 | 135,900 | 0.12% | Shares |
| STEMPOINT CAPITAL LP | $3,819,611 | 135,736 | 0.12% | Shares |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $3,795,000 | 134,850 | 0.12% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $3,723,794 | 132,331 | 0.12% | Shares |
| Quantinno Capital Management LP | $3,688,929 | 131,092 | 0.11% | Shares |
| Elmind Capital, LP | $3,658,200 | 130,000 | 0.11% | Shares |
| STIFEL FINANCIAL CORP | $3,097,510 | 110,075 | 0.10% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,943,444 | 104,600 | 0.09% | Call option |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2,820,050 | 100,215 | 0.09% | Shares |
| Caption Management, LLC | $2,814,000 | 100,000 | 0.09% | Call option |
| Ghisallo Capital Management LLC | $2,814,000 | 100,000 | 0.09% | Shares |
| TD Asset Management Inc | $2,729,636 | 97,002 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $2,723,010 | 96,767 | 0.08% | Shares |
| FIRST TRUST ADVISORS LP | $2,646,454 | 94,046 | 0.08% | Shares |
| Harvest Investment Services, LLC | $2,610,407 | 92,765 | 0.08% | Shares |
| Caption Management, LLC | $2,532,600 | 90,000 | 0.08% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,490,390 | 88,500 | 0.08% | Call option |
| DEUTSCHE BANK AG\ | $2,366,939 | 84,113 | 0.07% | Shares |
| ALLIANCEBERNSTEIN L.P. | $2,299,800 | 104,394 | 0.07% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2,217,939 | 78,818 | 0.07% | Shares |
| Ally Bridge Group (NY) LLC | $2,151,556 | 76,459 | 0.07% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,040,150 | 72,500 | 0.06% | Put option |
| Mariner, LLC | $2,018,263 | 71,726 | 0.06% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1,808,090 | 82,074 | 0.06% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,652,296 | 58,717 | 0.05% | Shares |
| ALGERT GLOBAL LLC | $1,625,648 | 57,770 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $1,581,468 | 56,200 | 0.05% | Call option |
| Legal & General Group Plc | $1,545,730 | 54,930 | 0.05% | Shares |
| ACT CAPITAL MANAGEMENT, LLC | $1,452,024 | 51,600 | 0.04% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $1,424,306 | 50,615 | 0.04% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $1,418,622 | 50,413 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $1,400,134 | 49,756 | 0.04% | Shares |
| Squarepoint Ops LLC | $1,339,183 | 47,590 | 0.04% | Shares |
| MetLife Investment Management, LLC | $1,303,220 | 46,312 | 0.04% | Shares |
| CITADEL ADVISORS LLC | $1,224,090 | 43,500 | 0.04% | Put option |
| FRED ALGER MANAGEMENT, LLC | $1,211,624 | 43,057 | 0.04% | Shares |
| Creative Planning | $1,176,759 | 41,818 | 0.04% | Shares |
| JANE STREET GROUP, LLC | $1,136,856 | 40,400 | 0.04% | Put option |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1,023,536 | 36,373 | 0.03% | Shares |
| Corient Private Wealth LP | $988,953 | 35,144 | 0.03% | Shares |
| Trexquant Investment LP | $960,615 | 34,137 | 0.03% | Shares |
| FRANKLIN RESOURCES INC | $918,321 | 32,634 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $882,949 | 31,377 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $781,363 | 27,767 | 0.02% | Shares |
| J. Goldman & Co LP | $727,306 | 25,846 | 0.02% | Shares |
| Jain Global LLC | $710,704 | 25,256 | 0.02% | Shares |
| Y-Intercept (Hong Kong) Ltd | $710,141 | 25,236 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $680,988 | 24,200 | 0.02% | Call option |
| BNP PARIBAS FINANCIAL MARKETS | $677,555 | 24,078 | 0.02% | Shares |
| FOX RUN MANAGEMENT, L.L.C. | $675,163 | 23,993 | 0.02% | Shares |
| Inscription Capital, LLC | $664,076 | 23,599 | 0.02% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $656,647 | 23,335 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $655,521 | 23,295 | 0.02% | Shares |
| XTX Topco Ltd | $642,549 | 22,834 | 0.02% | Shares |
| State of New Jersey Common Pension Fund D | $616,238 | 21,899 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $586,803 | 20,853 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $552,782 | 19,644 | 0.02% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $525,880 | 18,688 | 0.02% | Shares |
| Vanguard Investments Australia, Ltd. | $457,894 | 16,272 | 0.01% | Shares |
| Persistent Asset Partners Ltd | $443,667 | 508 | 0.01% | Call option |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $433,243 | 15,396 | 0.01% | Shares |
| OCCUDO QUANTITATIVE STRATEGIES LP | $430,458 | 15,297 | 0.01% | Shares |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $422,100 | 15,000 | 0.01% | Shares |
| Brevan Howard Capital Management LP | $416,782 | 14,811 | 0.01% | Shares |
| ProShare Advisors LLC | $405,020 | 14,393 | 0.01% | Shares |
| PROFUND ADVISORS LLC | $401,023 | 14,251 | 0.01% | Shares |
| OpenArc Corporate Advisory, LLC | $400,714 | 14,240 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $399,588 | 14,200 | 0.01% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $382,817 | 13,604 | 0.01% | Shares |
| Virtus Investment Advisers, LLC | $381,269 | 13,549 | 0.01% | Shares |
| TWO SIGMA ADVISERS, LP | $371,602 | 38,074 | 0.01% | Shares |
| Point72 Asset Management, L.P. | $343,308 | 12,200 | 0.01% | Call option |
| Point72 Asset Management, L.P. | $343,308 | 12,200 | 0.01% | Put option |
| Verdad Advisers, LP | $342,942 | 12,187 | 0.01% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $322,119 | 11,447 | 0.01% | Shares |
| SmartHarvest Portfolios, LLC | $303,096 | 10,771 | 0.01% | Shares |
| Allianz Asset Management GmbH | $301,098 | 10,700 | 0.01% | Shares |
| Vanguard Personalized Indexing Management, LLC | $300,169 | 10,667 | 0.01% | Shares |
| Voleon Capital Management LP | $299,550 | 10,645 | 0.01% | Shares |
| Pictet Asset Management Holding SA | $295,217 | 10,491 | 0.01% | Shares |
| Rafferty Asset Management, LLC | $278,670 | 9,903 | 0.01% | Shares |
| CAPSTONE INVESTMENT ADVISORS, LLC | $236,967 | 8,421 | 0.01% | Shares |
| SEI INVESTMENTS CO | $234,621 | 8,337 | 0.01% | Shares |
| Vident Advisory, LLC | $233,449 | 8,296 | 0.01% | Shares |
| CWM, LLC | $228,870 | 10,389 | 0.01% | Shares |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $222,081 | 7,892 | 0.01% | Shares |
| Arax Advisory Partners | $221,884 | 7,885 | 0.01% | Shares |
| XPONANCE LLC | $218,113 | 7,751 | 0.01% | Shares |
| HAP Trading, LLC | $213,125 | 402,500 | 0.01% | Put option |
| Abel Hall, LLC | $209,277 | 7,437 | 0.01% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $201,794 | 7,128 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $201,708 | 7,168 | 0.01% | Shares |
| Fulcrum Asset Management LLP | $193,128 | 7,116 | 0.01% | Shares |
| State of Wyoming | $188,876 | 6,712 | 0.01% | Shares |
| Farther Finance Advisors, LLC | $174,890 | 6,215 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $155,333 | 5,520 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $153,279 | 5,447 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $146,325 | 5,199,838 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $140,306 | 4,986 | 0.00% | Shares |
| ASSETMARK, INC | $118,441 | 4,209 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $75,331 | 2,677 | 0.00% | Shares |
| STRS OHIO | $73,164 | 2,600 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $72,630 | 2,581 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $72,000 | 2,559 | 0.00% | Shares |
| Parallel Advisors, LLC | $57,940 | 2,059 | 0.00% | Shares |
| SIGNATUREFD, LLC | $36,188 | 1,286 | 0.00% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $32,839 | 1,167 | 0.00% | Shares |
| GAMMA Investing LLC | $27,971 | 994 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $27,852 | 1,055 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $27,774 | 987 | 0.00% | Shares |
| Kemnay Advisory Services Inc. | $25,664 | 912 | 0.00% | Shares |
| Global Retirement Partners, LLC | $15,280 | 543 | 0.00% | Shares |
| Allworth Financial LP | $13,142 | 467 | 0.00% | Shares |
| Essential Partners LLC | $12,382 | 440 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $11,566 | 411 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $11,031 | 392 | 0.00% | Shares |
| Aster Capital Management (DIFC) Ltd | $9,258 | 329 | 0.00% | Shares |
| COMERICA BANK | $9,096 | 932 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $8,188 | 291 | 0.00% | Shares |
| MassMutual Private Wealth & Trust, FSB | $7,851 | 279 | 0.00% | Shares |
| Sterling Capital Management LLC | $7,795 | 277 | 0.00% | Shares |
| US BANCORP \DE\ | $7,401 | 263 | 0.00% | Shares |
| True Wealth Design, LLC | $6,529 | 232 | 0.00% | Shares |
| BFSG, LLC | $5,403 | 192 | 0.00% | Shares |
| Larson Financial Group LLC | $4,334 | 154 | 0.00% | Shares |
| Versant Capital Management, Inc | $4,013 | 543 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $3,994 | 142 | 0.00% | Shares |
| Transamerica Financial Advisors, LLC | $2,729 | 97 | 0.00% | Shares |
| Quarry LP | $2,701 | 96 | 0.00% | Shares |
| Optiver Holding B.V. | $2,645 | 94 | 0.00% | Shares |
| Decker Retirement Planning Inc. | $2,561 | 91 | 0.00% | Shares |
| Fortitude Family Office, LLC | $2,167 | 77 | 0.00% | Shares |
| IFP Advisors, Inc | $1,548 | 55 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $957 | 34 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $900 | 32 | 0.00% | Shares |
| CoreCap Advisors, LLC | $732 | 26 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $703 | 25 | 0.00% | Shares |
| SG Americas Securities, LLC | $643 | 22,867 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $634 | 23 | 0.00% | Shares |
| Stone House Investment Management, LLC | $619 | 22 | 0.00% | Shares |
| SALEM INVESTMENT COUNSELORS INC | $563 | 20 | 0.00% | Shares |
| HAP Trading, LLC | $272 | 340,000 | 0.00% | Put option |
| HAP Trading, LLC | $260 | 266,900 | 0.00% | Call option |
| Sunbelt Securities, Inc. | $154 | 7 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $103 | 3,696 | 0.00% | Shares |
| KBC Group NV | $54 | 1,929 | 0.00% | Shares |
| Covestor Ltd | $1 | 28 | 0.00% | Shares |