ACHV — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $49,724,879 | 7,614,836 | 9.06% | Shares |
| TPG GP A, LLC | $44,910,597 | 6,877,580 | 8.19% | Shares |
| venBio Partners LLC | $38,623,122 | 5,914,720 | 7.04% | Shares |
| Logos Global Management LP | $35,425,250 | 5,425,000 | 6.46% | Shares |
| BlackRock, Inc. | $34,426,271 | 5,272,017 | 6.28% | Shares |
| FRANKLIN RESOURCES INC | $32,344,527 | 4,953,220 | 5.90% | Shares |
| Paradigm Biocapital Advisors LP | $32,335,620 | 4,951,856 | 5.89% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $27,039,502 | 4,140,812 | 4.93% | Shares |
| Propel Bio Management, LLC | $26,342,138 | 4,034,018 | 4.80% | Shares |
| MARSHALL WACE, LLP | $24,620,145 | 3,770,313 | 4.49% | Shares |
| STATE STREET CORP | $19,234,285 | 2,945,526 | 3.51% | Shares |
| Venrock Adviser, LLC | $17,964,239 | 2,751,032 | 3.27% | Shares |
| Vivo Capital, LLC | $17,964,239 | 2,751,032 | 3.27% | Shares |
| EVENTIDE ASSET MANAGEMENT, LLC | $14,496,600 | 2,220,000 | 2.64% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $13,471,818 | 2,062,721 | 2.46% | Shares |
| Alyeska Investment Group, L.P. | $12,574,965 | 1,925,722 | 2.29% | Shares |
| VANGUARD GROUP INC | $12,297,331 | 2,474,312 | 2.24% | Shares |
| Simplify Asset Management Inc. | $9,351,646 | 1,432,105 | 1.70% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $9,317,755 | 1,426,915 | 1.70% | Shares |
| Caption Management, LLC | $7,676,015 | 1,175,500 | 1.40% | Call option |
| LPL Financial LLC | $5,891,725 | 902,255 | 1.07% | Shares |
| NORTHERN TRUST CORP | $4,856,753 | 743,760 | 0.89% | Shares |
| Spruce Street Capital LP | $4,810,240 | 736,637 | 0.88% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,877,194 | 593,751 | 0.71% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3,771,075 | 577,500 | 0.69% | Call option |
| RAYMOND JAMES FINANCIAL INC | $3,567,457 | 546,318 | 0.65% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3,510,502 | 537,596 | 0.64% | Shares |
| KVP Capital Advisors, LP | $3,019,178 | 462,355 | 0.55% | Shares |
| TWO SIGMA INVESTMENTS, LP | $2,880,951 | 441,187 | 0.53% | Shares |
| UBS Group AG | $2,043,916 | 313,004 | 0.37% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,515,861 | 232,138 | 0.28% | Shares |
| Caption Management, LLC | $1,487,096 | 227,733 | 0.27% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1,483,472 | 227,178 | 0.27% | Shares |
| Bank of New York Mellon Corp | $1,424,364 | 218,126 | 0.26% | Shares |
| JANE STREET GROUP, LLC | $1,331,467 | 203,900 | 0.24% | Call option |
| CITADEL ADVISORS LLC | $1,326,243 | 203,100 | 0.24% | Call option |
| Nuveen, LLC | $1,248,210 | 191,150 | 0.23% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,208,540 | 185,075 | 0.22% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,162,660 | 178,049 | 0.21% | Shares |
| WELLS FARGO & COMPANY/MN | $1,114,233 | 170,633 | 0.20% | Shares |
| TWO SIGMA ADVISERS, LP | $1,043,203 | 209,900 | 0.19% | Shares |
| CITADEL ADVISORS LLC | $804,032 | 123,129 | 0.15% | Shares |
| CANTOR FITZGERALD, L. P. | $794,250 | 121,631 | 0.14% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $791,534 | 121,215 | 0.14% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $677,161 | 103,700 | 0.12% | Put option |
| Shay Capital LLC | $606,049 | 92,810 | 0.11% | Shares |
| XTX Topco Ltd | $587,896 | 90,030 | 0.11% | Shares |
| RHUMBLINE ADVISERS | $568,253 | 87,023 | 0.10% | Shares |
| Blue Trust, Inc. | $560,849 | 85,888 | 0.10% | Shares |
| Diametric Capital, LP | $530,098 | 81,179 | 0.10% | Shares |
| DEUTSCHE BANK AG\ | $505,977 | 77,485 | 0.09% | Shares |
| CITIGROUP INC | $483,965 | 74,114 | 0.09% | Shares |
| MANCHESTER FINANCIAL INC | $438,666 | 67,177 | 0.08% | Shares |
| MEMBERS WEALTH LLC | $435,962 | 66,763 | 0.08% | Shares |
| MORGAN STANLEY | $387,713 | 59,374 | 0.07% | Shares |
| Virtus Investment Advisers, LLC | $387,066 | 59,275 | 0.07% | Shares |
| ADAR1 Capital Management, LLC | $351,314 | 53,800 | 0.06% | Shares |
| JANE STREET GROUP, LLC | $329,478 | 50,456 | 0.06% | Shares |
| MetLife Investment Management, LLC | $300,282 | 45,985 | 0.05% | Shares |
| OSAIC HOLDINGS, INC. | $281,540 | 43,115 | 0.05% | Shares |
| WINTON GROUP Ltd | $277,525 | 42,500 | 0.05% | Shares |
| Invesco Ltd. | $276,167 | 42,292 | 0.05% | Shares |
| GOLDMAN SACHS GROUP INC | $267,573 | 40,976 | 0.05% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $260,219 | 40,050 | 0.05% | Shares |
| Rafferty Asset Management, LLC | $245,012 | 37,521 | 0.04% | Shares |
| Next Capital Management LLC | $228,517 | 34,995 | 0.04% | Shares |
| AMERIFLEX GROUP, INC. | $219,395 | 33,598 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $211,624 | 32,408 | 0.04% | Shares |
| JPMORGAN CHASE & CO | $201,160 | 32,289 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $198,329 | 30,372 | 0.04% | Shares |
| Rockefeller Capital Management L.P. | $195,900 | 30,000 | 0.04% | Shares |
| Jones Hill Capital LP | $174,743 | 26,760 | 0.03% | Shares |
| BCV Asset Management Inc. | $164,591 | 26,365 | 0.03% | Shares |
| AXQ CAPITAL, LP | $164,380 | 25,173 | 0.03% | Shares |
| Robertson Stephens Wealth Management, LLC | $163,250 | 25,000 | 0.03% | Shares |
| Keating Financial Advisory Services, Inc. | $162,669 | 24,911 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $149,916 | 22,958 | 0.03% | Shares |
| ALLIANCEBERNSTEIN L.P. | $143,884 | 48,940 | 0.03% | Shares |
| Scientech Research LLC | $143,706 | 22,007 | 0.03% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $134,583 | 20,610 | 0.02% | Shares |
| SEI INVESTMENTS CO | $133,865 | 20,500 | 0.02% | Shares |
| BARCLAYS PLC | $130,561 | 19,994 | 0.02% | Shares |
| PROFUND ADVISORS LLC | $129,660 | 19,856 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $125,376 | 19,200 | 0.02% | Shares |
| nVerses Capital, LLC | $118,852 | 18,201 | 0.02% | Shares |
| FMR LLC | $115,628 | 17,707 | 0.02% | Shares |
| Cubist Systematic Strategies, LLC | $111,898 | 35,523 | 0.02% | Shares |
| MAGNOLIA CAPITAL ADVISORS LLC | $98,603 | 15,100 | 0.02% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $96,931 | 14,844 | 0.02% | Shares |
| SBI Securities Co., Ltd. | $96,912 | 14,841 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $89,696 | 13,736 | 0.02% | Shares |
| StoneX Group Inc. | $86,507 | 16,342 | 0.02% | Shares |
| PRUDENTIAL FINANCIAL INC | $85,151 | 13,040 | 0.02% | Shares |
| Alpine Global Management, LLC | $81,625 | 12,500 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $81,000 | 12,376 | 0.01% | Shares |
| Windsor Capital Management, LLC | $70,635 | 10,817 | 0.01% | Shares |
| ProShare Advisors LLC | $66,554 | 10,192 | 0.01% | Shares |
| Legal & General Group Plc | $49,334 | 7,555 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $46,128 | 7,064 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $41,622 | 6,374 | 0.01% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $23,641 | 7,505 | 0.00% | Shares |
| Allworth Financial LP | $19,590 | 3,000 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $19,551 | 2,994 | 0.00% | Shares |
| Persistent Asset Partners Ltd | $18,153 | 2,780 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $15,881 | 2,432 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $14,954 | 2,290 | 0.00% | Shares |
| Federation des caisses Desjardins du Quebec | $13,060 | 2,000 | 0.00% | Shares |
| COMERICA BANK | $11,839 | 2,382 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $7,000 | 1,072 | 0.00% | Shares |
| CWM, LLC | $5,004 | 1,702 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $4,826 | 739 | 0.00% | Shares |
| SITTNER & NELSON, LLC | $4,395 | 673 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $1,806 | 300 | 0.00% | Shares |
| Sterling Capital Management LLC | $1,783 | 273 | 0.00% | Shares |
| Versant Capital Management, Inc | $1,715 | 212 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $595 | 189 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $423 | 64,769 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $131 | 20 | 0.00% | Shares |
| Arax Advisory Partners | $65 | 10 | 0.00% | Shares |
| Optiver Holding B.V. | $13 | 2 | 0.00% | Shares |
| Capital Analysts, LLC | $5 | 700 | 0.00% | Shares |
| Pacer Advisors, Inc. | $4 | 627 | 0.00% | Shares |
| Avion Wealth | $3 | 500 | 0.00% | Shares |