OVID — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| EVENTIDE ASSET MANAGEMENT, LLC | $31,774,928 | 11,812,241 | 8.39% | Shares |
| BlackRock, Inc. | $29,115,162 | 10,823,480 | 7.68% | Shares |
| RA CAPITAL MANAGEMENT, L.P. | $28,247,604 | 10,500,968 | 7.45% | Shares |
| Affinity Asset Advisors, LLC | $27,288,872 | 10,144,562 | 7.20% | Shares |
| JANUS HENDERSON GROUP PLC | $23,731,510 | 10,714,000 | 6.26% | Shares |
| STATE STREET CORP | $21,253,058 | 7,900,765 | 5.61% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $20,874,707 | 7,760,114 | 5.51% | Shares |
| ADAR1 Capital Management, LLC | $19,953,019 | 7,417,479 | 5.27% | Shares |
| Balyasny Asset Management L.P. | $18,074,314 | 6,719,076 | 4.77% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $16,580,571 | 6,163,781 | 4.38% | Shares |
| FEDERATED HERMES, INC. | $16,009,982 | 5,951,666 | 4.23% | Shares |
| BRAIDWELL LP | $15,923,358 | 5,919,464 | 4.20% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $10,957,549 | 4,072,653 | 2.89% | Shares |
| TAKEDA PHARMACEUTICAL CO LTD | $9,791,595 | 7,531,996 | 2.58% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8,342,037 | 3,101,129 | 2.20% | Shares |
| STEMPOINT CAPITAL LP | $6,502,491 | 2,417,283 | 1.72% | Shares |
| Ikarian Capital, LLC | $6,105,503 | 2,269,704 | 1.61% | Shares |
| Point72 Asset Management, L.P. | $5,234,006 | 1,945,727 | 1.38% | Shares |
| VANGUARD GROUP INC | $5,007,730 | 3,072,227 | 1.32% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $3,639,570 | 1,353,000 | 0.96% | Shares |
| NORTHERN TRUST CORP | $3,352,114 | 1,246,139 | 0.88% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,068,626 | 1,140,753 | 0.81% | Shares |
| Propel Bio Management, LLC | $3,000,797 | 1,115,538 | 0.79% | Shares |
| Rosalind Advisors, Inc. | $2,980,504 | 1,107,994 | 0.79% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2,773,237 | 1,030,943 | 0.73% | Shares |
| Sio Capital Management, LLC | $2,704,348 | 1,005,334 | 0.71% | Shares |
| Ensign Peak Advisors, Inc | $2,657,946 | 988,084 | 0.70% | Shares |
| Nuveen, LLC | $2,402,853 | 893,254 | 0.63% | Shares |
| TWO SIGMA INVESTMENTS, LP | $2,239,097 | 832,378 | 0.59% | Shares |
| WELLS FARGO & COMPANY/MN | $2,222,494 | 826,206 | 0.59% | Shares |
| ORBIMED ADVISORS LLC | $2,009,430 | 747,000 | 0.53% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $1,984,569 | 737,758 | 0.52% | Shares |
| Saturn V Capital Management LP | $1,783,631 | 663,060 | 0.47% | Shares |
| Ally Bridge Group (NY) LLC | $1,680,069 | 624,561 | 0.44% | Shares |
| UBS Group AG | $1,234,487 | 458,917 | 0.33% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,194,473 | 444,042 | 0.32% | Shares |
| Bank of New York Mellon Corp | $1,119,897 | 416,318 | 0.30% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,101,528 | 409,490 | 0.29% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $1,043,445 | 387,767 | 0.28% | Shares |
| GOLDMAN SACHS GROUP INC | $894,942 | 332,692 | 0.24% | Shares |
| Informed Momentum Co LLC | $698,407 | 259,631 | 0.18% | Shares |
| Atom Investors LP | $677,439 | 251,836 | 0.18% | Shares |
| CIBC WORLD MARKET INC. | $588,709 | 218,851 | 0.16% | Shares |
| Parkman Healthcare Partners LLC | $532,477 | 197,947 | 0.14% | Shares |
| SEI INVESTMENTS CO | $529,083 | 196,685 | 0.14% | Shares |
| CITIGROUP INC | $513,946 | 191,058 | 0.14% | Shares |
| Invesco Ltd. | $470,481 | 174,900 | 0.12% | Shares |
| RHUMBLINE ADVISERS | $457,666 | 170,139 | 0.12% | Shares |
| AMERICAN CENTURY COMPANIES INC | $455,638 | 169,382 | 0.12% | Shares |
| DEUTSCHE BANK AG\ | $401,862 | 149,391 | 0.11% | Shares |
| TWO SIGMA ADVISERS, LP | $389,896 | 239,200 | 0.10% | Shares |
| Rafferty Asset Management, LLC | $367,922 | 136,774 | 0.10% | Shares |
| Velan Capital Investment Management LP | $349,700 | 130,000 | 0.09% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $303,701 | 112,900 | 0.08% | Call option |
| RENAISSANCE TECHNOLOGIES LLC | $283,795 | 105,500 | 0.07% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $278,146 | 103,400 | 0.07% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $256,717 | 95,434 | 0.07% | Shares |
| Empowered Funds, LLC | $245,419 | 91,234 | 0.06% | Shares |
| MetLife Investment Management, LLC | $243,679 | 90,587 | 0.06% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $232,080 | 86,098 | 0.06% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $198,791 | 73,900 | 0.05% | Put option |
| TWO SIGMA SECURITIES, LLC | $192,300 | 71,487 | 0.05% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $189,914 | 70,600 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $189,718 | 70,527 | 0.05% | Shares |
| PROFUND ADVISORS LLC | $187,490 | 69,699 | 0.05% | Shares |
| ALLIANCEBERNSTEIN L.P. | $173,737 | 78,260 | 0.05% | Shares |
| JPMORGAN CHASE & CO | $172,671 | 63,482 | 0.05% | Shares |
| MORGAN STANLEY | $153,111 | 56,919 | 0.04% | Shares |
| State of Wyoming | $143,748 | 53,438 | 0.04% | Shares |
| LPL Financial LLC | $134,769 | 50,100 | 0.04% | Shares |
| Police & Firemen's Retirement System of New Jersey | $121,483 | 45,161 | 0.03% | Shares |
| Cubist Systematic Strategies, LLC | $112,648 | 86,652 | 0.03% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $110,048 | 40,910 | 0.03% | Shares |
| FMR LLC | $104,937 | 39,010 | 0.03% | Shares |
| D. E. Shaw & Co., Inc. | $99,199 | 36,877 | 0.03% | Shares |
| Verdad Advisers, LP | $95,627 | 35,549 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $95,226 | 35,400 | 0.03% | Shares |
| Schonfeld Strategic Advisors LLC | $94,281 | 35,049 | 0.02% | Shares |
| XTX Topco Ltd | $92,375 | 34,340 | 0.02% | Shares |
| BARCLAYS PLC | $91,783 | 34,120 | 0.02% | Shares |
| MILLENNIUM MANAGEMENT LLC | $86,874 | 32,295 | 0.02% | Shares |
| Spark Investment Management LLC | $85,542 | 31,800 | 0.02% | Shares |
| Sovereign Financial Group, Inc. | $80,700 | 30,000 | 0.02% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $78,758 | 29,278 | 0.02% | Shares |
| BLAIR WILLIAM & CO/IL | $77,577 | 28,839 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $77,542 | 28,826 | 0.02% | Shares |
| Abel Hall, LLC | $76,192 | 28,324 | 0.02% | Shares |
| Total Clarity Wealth Management, Inc. | $73,736 | 27,411 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $71,016 | 26,400 | 0.02% | Call option |
| FIRST MANHATTAN CO. LLC. | $69,940 | 26,000 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $64,226 | 23,876 | 0.02% | Shares |
| PRUDENTIAL FINANCIAL INC | $62,126 | 23,095 | 0.02% | Shares |
| Stonepine Capital Management, LLC | $57,297 | 21,300 | 0.02% | Shares |
| Creative Planning | $56,485 | 20,998 | 0.01% | Shares |
| ProShare Advisors LLC | $53,933 | 20,049 | 0.01% | Shares |
| Focus Partners Advisor Solutions, LLC | $53,800 | 20,000 | 0.01% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $52,046 | 19,348 | 0.01% | Shares |
| CITADEL ADVISORS LLC | $51,917 | 19,300 | 0.01% | Put option |
| E Fund Management Co., Ltd. | $51,879 | 19,286 | 0.01% | Shares |
| Benin Management CORP | $51,110 | 19,000 | 0.01% | Shares |
| Squarepoint Ops LLC | $50,941 | 18,937 | 0.01% | Shares |
| TLS Advisors LLC | $50,728 | 18,858 | 0.01% | Shares |
| GROUP ONE TRADING LLC | $50,203 | 18,663 | 0.01% | Shares |
| Assenagon Asset Management S.A. | $47,193 | 17,544 | 0.01% | Shares |
| Cetera Investment Advisers | $45,730 | 17,000 | 0.01% | Shares |
| Legal & General Group Plc | $39,968 | 14,858 | 0.01% | Shares |
| XPONANCE LLC | $39,166 | 14,560 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $37,380 | 13,896 | 0.01% | Shares |
| Caitong International Asset Management Co., Ltd | $36,014 | 13,388 | 0.01% | Shares |
| Private Advisor Group, LLC | $35,441 | 13,175 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $32,871 | 12,220 | 0.01% | Shares |
| Allspring Global Investments Holdings, LLC | $30,576 | 11,262 | 0.01% | Shares |
| Aaron Wealth Advisors LLC | $30,219 | 11,234 | 0.01% | Shares |
| Quadcap Wealth Management, LLC | $29,889 | 11,111 | 0.01% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $24,925 | 19,173 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $16,581 | 6,164 | 0.00% | Shares |
| Optiver Holding B.V. | $13,711 | 5,097 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $13,000 | 4,792 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $10,760 | 4,000 | 0.00% | Shares |
| Sterling Capital Management LLC | $7,494 | 2,786 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $7,459 | 2,925 | 0.00% | Shares |
| Clearstead Advisors, LLC | $7,355 | 2,734 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $6,324 | 2,351 | 0.00% | Shares |
| Atlantic Union Bankshares Corp | $6,187 | 2,300 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5,673 | 2,109 | 0.00% | Shares |
| H D Vest Advisory Services | $5,608 | 17,000 | 0.00% | Shares |
| Truvestments Capital LLC | $3,564 | 1,325 | 0.00% | Shares |
| TFC Financial Management, Inc. | $2,690 | 1,000 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $2,429 | 903 | 0.00% | Shares |
| Fortitude Family Office, LLC | $839 | 312 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $823 | 306 | 0.00% | Shares |
| Sandy Spring Bank | $718 | 2,300 | 0.00% | Shares |
| HUNTINGTON NATIONAL BANK | $371 | 213 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $339 | 125,725 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $256 | 197 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $239 | 89 | 0.00% | Shares |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $207 | 77 | 0.00% | Shares |
| Arax Advisory Partners | $153 | 57 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $80 | 30 | 0.00% | Shares |
| SG Americas Securities, LLC | $37 | 13,613 | 0.00% | Shares |
| Pacer Advisors, Inc. | $6 | 2,284 | 0.00% | Shares |
| Avion Wealth | $0 | 300 | 0.00% | Shares |