ZBIO — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $241,280,071 | 9,506,701 | 15.37% | Shares |
| SR One Capital Management, LP | $127,860,735 | 5,037,854 | 8.15% | Shares |
| NEA Management Company, LLC | $102,109,298 | 4,023,219 | 6.50% | Shares |
| ENAVATE SCIENCES GP, LLC | $99,468,255 | 3,919,159 | 6.34% | Shares |
| FEDERATED HERMES, INC. | $79,104,511 | 3,116,805 | 5.04% | Shares |
| BlackRock, Inc. | $68,176,389 | 2,686,225 | 4.34% | Shares |
| Capital International Investors | $63,523,907 | 2,502,912 | 4.05% | Shares |
| Polar Capital Holdings Plc | $61,236,153 | 2,412,772 | 3.90% | Shares |
| Royalty Pharma Sub-Manager, LLC | $60,611,247 | 2,388,150 | 3.86% | Shares |
| Fairmount Funds Management LLC | $59,872,055 | 2,359,025 | 3.81% | Shares |
| VANGUARD GROUP INC | $52,760,791 | 1,453,065 | 3.36% | Shares |
| STATE STREET CORP | $52,158,438 | 2,055,100 | 3.32% | Shares |
| NVP ASSOCIATES, LLC | $46,660,673 | 1,838,482 | 2.97% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $40,451,126 | 1,593,819 | 2.58% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $34,386,448 | 1,354,864 | 2.19% | Shares |
| BANK OF AMERICA CORP /DE/ | $31,246,815 | 1,231,159 | 1.99% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $22,406,450 | 882,654 | 1.43% | Shares |
| ALLIANCEBERNSTEIN L.P. | $21,571,235 | 1,103,388 | 1.37% | Shares |
| TWO SIGMA INVESTMENTS, LP | $20,688,507 | 815,150 | 1.32% | Shares |
| EcoR1 Capital, LLC | $20,037,510 | 789,500 | 1.28% | Shares |
| MILLENNIUM MANAGEMENT LLC | $16,762,729 | 660,470 | 1.07% | Shares |
| Woodline Partners LP | $14,987,880 | 590,539 | 0.95% | Shares |
| Balyasny Asset Management L.P. | $14,637,077 | 576,717 | 0.93% | Shares |
| ArrowMark Colorado Holdings LLC | $14,550,811 | 573,318 | 0.93% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $12,938,445 | 509,789 | 0.82% | Shares |
| Rock Springs Capital Management LP | $12,742,714 | 502,077 | 0.81% | Shares |
| Pivotal bioVenture Partners Investment Advisor LLC | $12,455,641 | 490,766 | 0.79% | Shares |
| NEXTBio Capital Management LP | $10,830,560 | 426,736 | 0.69% | Shares |
| Vestal Point Capital, LP | $9,263,700 | 365,000 | 0.59% | Shares |
| MARSHALL WACE, LLP | $8,208,957 | 323,442 | 0.52% | Shares |
| JENNISON ASSOCIATES LLC | $7,970,564 | 314,049 | 0.51% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $7,737,601 | 304,870 | 0.49% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,666,917 | 302,085 | 0.49% | Shares |
| NORTHERN TRUST CORP | $7,135,334 | 281,140 | 0.45% | Shares |
| GOLDMAN SACHS GROUP INC | $6,882,117 | 271,163 | 0.44% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,462,332 | 254,623 | 0.41% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $5,858,567 | 230,834 | 0.37% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5,740,956 | 226,200 | 0.37% | Call option |
| Walleye Capital LLC | $5,305,689 | 209,050 | 0.34% | Shares |
| Sio Capital Management, LLC | $5,293,177 | 208,557 | 0.34% | Shares |
| CITADEL ADVISORS LLC | $4,968,897 | 195,780 | 0.32% | Shares |
| UBS Group AG | $4,519,899 | 178,089 | 0.29% | Shares |
| Voleon Capital Management LP | $4,242,140 | 167,145 | 0.27% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $3,834,563 | 151,086 | 0.24% | Shares |
| MORGAN STANLEY | $3,425,767 | 134,979 | 0.22% | Shares |
| Squarepoint Ops LLC | $3,177,195 | 125,185 | 0.20% | Shares |
| BARCLAYS PLC | $2,943,193 | 115,965 | 0.19% | Shares |
| SEVEN GRAND MANAGERS, LLC | $2,538,000 | 100,000 | 0.16% | Shares |
| Birchview Capital, LP | $2,375,593 | 93,601 | 0.15% | Shares |
| Verition Fund Management LLC | $1,852,435 | 72,988 | 0.12% | Shares |
| Bank of New York Mellon Corp | $1,788,706 | 70,477 | 0.11% | Shares |
| J. Goldman & Co LP | $1,731,728 | 68,232 | 0.11% | Shares |
| Nuveen, LLC | $1,691,273 | 66,638 | 0.11% | Shares |
| ALPS ADVISORS INC | $1,616,072 | 63,675 | 0.10% | Shares |
| Swiss National Bank | $1,350,216 | 53,200 | 0.09% | Shares |
| Exome Asset Management LLC | $1,331,003 | 52,443 | 0.08% | Shares |
| Jump Financial, LLC | $1,294,939 | 51,022 | 0.08% | Shares |
| CITIGROUP INC | $1,256,843 | 49,521 | 0.08% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1,230,042 | 48,465 | 0.08% | Shares |
| XTX Topco Ltd | $1,016,063 | 40,034 | 0.06% | Shares |
| Burkehill Global Management, LP | $1,015,200 | 40,000 | 0.06% | Shares |
| JANE STREET GROUP, LLC | $989,820 | 39,000 | 0.06% | Call option |
| Rafferty Asset Management, LLC | $951,978 | 37,509 | 0.06% | Shares |
| Atom Investors LP | $942,842 | 37,149 | 0.06% | Shares |
| RHUMBLINE ADVISERS | $869,128 | 34,245 | 0.06% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $844,646 | 33,280 | 0.05% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $789,319 | 31,100 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $784,242 | 30,900 | 0.05% | Call option |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $747,974 | 29,471 | 0.05% | Shares |
| DEUTSCHE BANK AG\ | $733,000 | 28,881 | 0.05% | Shares |
| DCF Advisers, LLC | $715,310 | 28,184 | 0.05% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $683,280 | 26,922 | 0.04% | Shares |
| JPMORGAN CHASE & CO | $660,518 | 24,445 | 0.04% | Shares |
| WELLS FARGO & COMPANY/MN | $659,753 | 25,995 | 0.04% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $523,412 | 20,623 | 0.03% | Shares |
| Legal & General Group Plc | $508,182 | 20,023 | 0.03% | Shares |
| Invesco Ltd. | $481,053 | 18,954 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479,682 | 18,900 | 0.03% | Put option |
| China Universal Asset Management Co., Ltd. | $478,362 | 18,848 | 0.03% | Shares |
| PROFUND ADVISORS LLC | $478,108 | 18,838 | 0.03% | Shares |
| ALLSTATE CORP | $462,957 | 18,241 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $442,936 | 17,423 | 0.03% | Shares |
| Y-Intercept (Hong Kong) Ltd | $439,886 | 17,332 | 0.03% | Shares |
| MetLife Investment Management, LLC | $432,501 | 17,041 | 0.03% | Shares |
| Virtus Investment Advisers, LLC | $419,405 | 16,525 | 0.03% | Shares |
| Point72 Asset Management, L.P. | $409,532 | 16,136 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $389,126 | 15,332 | 0.02% | Shares |
| NORDEA INVESTMENT MANAGEMENT AB | $382,872 | 15,050 | 0.02% | Shares |
| Brevan Howard Capital Management LP | $372,426 | 14,674 | 0.02% | Shares |
| Engineers Gate Manager LP | $329,432 | 12,980 | 0.02% | Shares |
| Russell Investments Group, Ltd. | $323,341 | 12,740 | 0.02% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $303,475 | 15,523 | 0.02% | Shares |
| Creative Planning | $297,530 | 11,723 | 0.02% | Shares |
| VARCOV Co. | $266,617 | 10,505 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $261,414 | 10,300 | 0.02% | Shares |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $229,765 | 9,053 | 0.01% | Shares |
| Scientech Research LLC | $229,131 | 9,028 | 0.01% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $225,222 | 8,874 | 0.01% | Shares |
| Quantinno Capital Management LP | $217,786 | 8,581 | 0.01% | Shares |
| State of New Jersey Common Pension Fund D | $217,532 | 8,571 | 0.01% | Shares |
| Police & Firemen's Retirement System of New Jersey | $213,649 | 8,418 | 0.01% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $203,852 | 8,032 | 0.01% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $191,949 | 7,563 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $154,818 | 6,100 | 0.01% | Shares |
| PNC Financial Services Group, Inc. | $120,277 | 4,739 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $106,571 | 4,199 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $71,673 | 2,824 | 0.00% | Shares |
| Ameritas Investment Partners, Inc. | $65,633 | 2,586 | 0.00% | Shares |
| TOUNJIAN ADVISORY PARTNERS, LLC | $63,450 | 2,500 | 0.00% | Shares |
| Quantbot Technologies LP | $48,933 | 1,928 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $32,639 | 1,286 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $31,141 | 1,226,928 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $28,882 | 1,138 | 0.00% | Shares |
| SIGNATUREFD, LLC | $28,781 | 1,134 | 0.00% | Shares |
| CWM, LLC | $28,778 | 1,472 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $21,000 | 847 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $16,522 | 651 | 0.00% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $13,680 | 539 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $13,654 | 538 | 0.00% | Shares |
| Larson Financial Group LLC | $11,523 | 454 | 0.00% | Shares |
| Global Retirement Partners, LLC | $10,660 | 420 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $9,391 | 370 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $8,756 | 345 | 0.00% | Shares |
| US BANCORP \DE\ | $7,716 | 304 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $7,487 | 295 | 0.00% | Shares |
| J.Safra Asset Management Corp | $5,685 | 224 | 0.00% | Shares |
| iA Global Asset Management Inc. | $5,460 | 215,130 | 0.00% | Shares |
| GAMMA Investing LLC | $4,949 | 195 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $4,112 | 162 | 0.00% | Shares |
| Arax Advisory Partners | $2,640 | 104 | 0.00% | Shares |
| Sterling Capital Management LLC | $2,538 | 100 | 0.00% | Shares |
| Bare Financial Services, Inc | $2,412 | 95 | 0.00% | Shares |
| Torren Management, LLC | $1,857 | 95 | 0.00% | Shares |
| CSM Advisors, LLC | $1,716 | 67,622 | 0.00% | Shares |
| Physician Wealth Advisors, Inc. | $1,701 | 67 | 0.00% | Shares |
| Ameritas Advisory Services, LLC | $1,066 | 42 | 0.00% | Shares |
| Fortitude Family Office, LLC | $736 | 29 | 0.00% | Shares |
| Cornerstone Financial Management LLC | $660 | 26 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $508 | 20 | 0.00% | Shares |
| CoreCap Advisors, LLC | $305 | 12 | 0.00% | Shares |
| HRT FINANCIAL LP | $225 | 8,879 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $215 | 11 | 0.00% | Shares |
| SG Americas Securities, LLC | $214 | 8,442 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $51 | 2 | 0.00% | Shares |
| Essential Partners LLC | $51 | 2 | 0.00% | Shares |
| Allworth Financial LP | $26 | 1 | 0.00% | Shares |
| Hughes Financial Services, LLC | $25 | 1 | 0.00% | Shares |
| Freestone Grove Partners LP | $25 | 1 | 0.00% | Shares |
| Pacer Advisors, Inc. | $16 | 626 | 0.00% | Shares |
| Covestor Ltd | $1 | 22 | 0.00% | Shares |