AVTX — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $94,251,992 | 5,100,216 | 7.16% | Shares |
| BlackRock, Inc. | $80,675,418 | 4,365,553 | 6.13% | Shares |
| Deep Track Capital, LP | $66,712,800 | 3,610,000 | 5.07% | Shares |
| Caligan Partners LP | $58,468,244 | 3,163,866 | 4.44% | Shares |
| TCG Crossover Management, LLC | $55,756,378 | 3,017,120 | 4.24% | Shares |
| Affinity Asset Advisors, LLC | $53,592,000 | 2,900,000 | 4.07% | Shares |
| STATE STREET CORP | $53,394,024 | 2,889,287 | 4.06% | Shares |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $46,163,040 | 2,498,000 | 3.51% | Shares |
| Point72 Asset Management, L.P. | $44,112,240 | 2,387,026 | 3.35% | Shares |
| Avoro Capital Advisors LLC | $43,119,994 | 2,333,333 | 3.28% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $41,843,266 | 2,264,246 | 3.18% | Shares |
| BVF INC/IL | $38,356,072 | 2,075,545 | 2.92% | Shares |
| BANK OF AMERICA CORP /DE/ | $35,367,561 | 1,913,829 | 2.69% | Shares |
| Nantahala Capital Management, LLC | $34,414,380 | 1,862,250 | 2.62% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $31,951,920 | 1,729,000 | 2.43% | Shares |
| Soleus Capital Management, L.P. | $30,583,993 | 1,654,978 | 2.32% | Shares |
| BRAIDWELL LP | $30,107,283 | 1,629,182 | 2.29% | Shares |
| ALLIANCEBERNSTEIN L.P. | $23,297,533 | 1,260,689 | 1.77% | Shares |
| UBS Group AG | $22,343,410 | 1,209,059 | 1.70% | Shares |
| Logos Global Management LP | $21,252,000 | 1,150,000 | 1.62% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $20,428,430 | 1,105,118 | 1.55% | Shares |
| Commodore Capital LP | $18,818,535 | 1,018,319 | 1.43% | Shares |
| RA CAPITAL MANAGEMENT, L.P. | $18,480,000 | 1,000,000 | 1.40% | Shares |
| GOLDMAN SACHS GROUP INC | $17,487,993 | 946,320 | 1.33% | Shares |
| Trails Edge Capital Partners, LP | $16,481,961 | 891,881 | 1.25% | Shares |
| AMERIPRISE FINANCIAL INC | $16,473,165 | 891,405 | 1.25% | Shares |
| Balyasny Asset Management L.P. | $15,924,419 | 861,711 | 1.21% | Shares |
| VANGUARD GROUP INC | $14,602,165 | 804,084 | 1.11% | Shares |
| Vestal Point Capital, LP | $14,322,000 | 775,000 | 1.09% | Shares |
| Seven Fleet Capital Management LP | $14,243,737 | 770,765 | 1.08% | Shares |
| Parkman Healthcare Partners LLC | $14,161,039 | 766,290 | 1.08% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $12,973,902 | 702,051 | 0.99% | Shares |
| Squarepoint Ops LLC | $10,889,248 | 589,245 | 0.83% | Shares |
| BAKER BROS. ADVISORS LP | $10,164,000 | 550,000 | 0.77% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $9,247,429 | 500,402 | 0.70% | Shares |
| Davern Capital Partners, LP | $8,660,948 | 468,666 | 0.66% | Shares |
| Pivotal bioVenture Partners Investment Advisor LLC | $8,020,930 | 434,033 | 0.61% | Shares |
| FRANKLIN RESOURCES INC | $7,469,450 | 404,191 | 0.57% | Shares |
| Boxer Capital Management, LLC | $6,930,000 | 375,000 | 0.53% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $6,601,056 | 357,200 | 0.50% | Shares |
| Caption Management, LLC | $6,371,904 | 344,800 | 0.48% | Put option |
| NORTHERN TRUST CORP | $6,366,748 | 344,521 | 0.48% | Shares |
| DV EQUITIES, LLC | $6,139,296 | 332,213 | 0.47% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,002,452 | 324,808 | 0.46% | Shares |
| Velan Capital Investment Management LP | $5,995,873 | 324,452 | 0.46% | Shares |
| CITADEL ADVISORS LLC | $5,984,434 | 323,833 | 0.45% | Shares |
| Schonfeld Strategic Advisors LLC | $5,728,947 | 310,008 | 0.44% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $5,261,293 | 284,702 | 0.40% | Shares |
| Vivo Capital, LLC | $5,082,000 | 275,000 | 0.39% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,470,312 | 241,900 | 0.34% | Call option |
| Eagle Health Investments LP | $4,344,519 | 235,093 | 0.33% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $4,292,793 | 232,294 | 0.33% | Shares |
| PERCEPTIVE ADVISORS LLC | $4,062,144 | 219,813 | 0.31% | Shares |
| Caption Management, LLC | $3,880,800 | 210,000 | 0.29% | Shares |
| Jump Financial, LLC | $3,731,149 | 201,902 | 0.28% | Shares |
| NAN FUNG TRINITY (HK) LTD | $3,492,720 | 189,000 | 0.27% | Shares |
| ACUTA CAPITAL PARTNERS, LLC | $3,442,972 | 186,308 | 0.26% | Shares |
| Walleye Capital LLC | $3,430,128 | 185,613 | 0.26% | Shares |
| RTW INVESTMENTS, LP | $3,234,000 | 175,000 | 0.25% | Shares |
| Ally Bridge Group (NY) LLC | $2,772,000 | 150,000 | 0.21% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2,540,538 | 137,475 | 0.19% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $2,477,928 | 134,087 | 0.19% | Shares |
| CenterBook Partners LP | $2,455,419 | 132,869 | 0.19% | Shares |
| MORGAN STANLEY | $2,366,826 | 128,075 | 0.18% | Shares |
| Moody Aldrich Partners LLC | $2,320,755 | 125,582 | 0.18% | Shares |
| HighVista Strategies LLC | $2,265,832 | 122,610 | 0.17% | Shares |
| Aberdeen Group plc | $2,257,683 | 122,169 | 0.17% | Shares |
| SECTORAL ASSET MANAGEMENT INC | $2,216,177 | 119,923 | 0.17% | Shares |
| CITADEL ADVISORS LLC | $2,080,848 | 112,600 | 0.16% | Call option |
| WELLINGTON MANAGEMENT GROUP LLP | $1,945,224 | 105,261 | 0.15% | Shares |
| Bank of New York Mellon Corp | $1,897,023 | 102,653 | 0.14% | Shares |
| Nuveen, LLC | $1,859,698 | 100,633 | 0.14% | Shares |
| LMR Partners LLP | $1,738,968 | 94,100 | 0.13% | Call option |
| Ikarian Capital, LLC | $1,666,581 | 90,183 | 0.13% | Shares |
| TD Asset Management Inc | $1,431,720 | 77,474 | 0.11% | Shares |
| CITIGROUP INC | $1,275,378 | 69,014 | 0.10% | Shares |
| TWO SIGMA INVESTMENTS, LP | $1,239,897 | 67,094 | 0.09% | Shares |
| JANE STREET GROUP, LLC | $1,068,144 | 57,800 | 0.08% | Call option |
| Rafferty Asset Management, LLC | $1,042,475 | 56,411 | 0.08% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $994,206 | 53,799 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $984,789 | 53,290 | 0.07% | Shares |
| XTX Topco Ltd | $971,734 | 52,583 | 0.07% | Shares |
| TWO SIGMA ADVISERS, LP | $897,104 | 49,400 | 0.07% | Shares |
| DEUTSCHE BANK AG\ | $760,747 | 41,166 | 0.06% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $706,919 | 38,158 | 0.05% | Shares |
| Verition Fund Management LLC | $706,675 | 38,240 | 0.05% | Shares |
| Man Group plc | $681,468 | 36,876 | 0.05% | Shares |
| WELLS FARGO & COMPANY/MN | $675,924 | 36,576 | 0.05% | Shares |
| Verdad Advisers, LP | $606,643 | 32,827 | 0.05% | Shares |
| LMR Partners LLP | $554,400 | 30,000 | 0.04% | Put option |
| PROFUND ADVISORS LLC | $523,150 | 28,309 | 0.04% | Shares |
| GLENMEDE TRUST CO NA | $522,614 | 28,280 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $503,155 | 27,227 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $480,465 | 25,712 | 0.04% | Shares |
| Persistent Asset Partners Ltd | $453,573 | 24,544 | 0.03% | Shares |
| MetLife Investment Management, LLC | $452,742 | 24,499 | 0.03% | Shares |
| ENVESTNET ASSET MANAGEMENT INC | $416,521 | 22,539 | 0.03% | Shares |
| Invesco Ltd. | $410,736 | 22,226 | 0.03% | Shares |
| Virtus Investment Advisers, LLC | $409,665 | 22,168 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $369,785 | 20,010 | 0.03% | Shares |
| JPMORGAN CHASE & CO | $350,018 | 18,145 | 0.03% | Shares |
| SEI INVESTMENTS CO | $331,365 | 17,931 | 0.03% | Shares |
| BARCLAYS PLC | $329,147 | 17,811 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $304,920 | 16,500 | 0.02% | Put option |
| ExodusPoint Capital Management, LP | $304,828 | 16,495 | 0.02% | Shares |
| Quadrature Capital Ltd | $284,684 | 15,405 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $271,656 | 14,700 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $255,024 | 13,800 | 0.02% | Put option |
| Jain Global LLC | $234,437 | 12,686 | 0.02% | Shares |
| Woodline Partners LP | $231,813 | 12,544 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $227,748 | 12,324 | 0.02% | Shares |
| FOX RUN MANAGEMENT, L.L.C. | $196,609 | 10,639 | 0.01% | Shares |
| Lynx1 Capital Management LP | $186,648 | 10,100 | 0.01% | Shares |
| Eversept Partners, LP | $184,800 | 10,000 | 0.01% | Shares |
| US BANCORP \DE\ | $105,040 | 5,684 | 0.01% | Shares |
| Byrne Asset Management LLC | $88,667 | 4,798 | 0.01% | Shares |
| Legal & General Group Plc | $74,896 | 4,055 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $70,076 | 3,792 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $61,741 | 3,341 | 0.00% | Shares |
| Allostery Investments LP | $44,910 | 9,000 | 0.00% | Shares |
| PFS Partners, LLC | $36,960 | 2,000 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $28,496 | 1,542 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $26,000 | 1,365 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $24,241 | 1,311,715 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $10,626 | 575 | 0.00% | Shares |
| Sterling Capital Management LLC | $9,055 | 490 | 0.00% | Shares |
| Versant Capital Management, Inc | $782 | 51 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $647 | 35 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $647 | 35 | 0.00% | Shares |
| Fortitude Family Office, LLC | $554 | 30 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $536 | 29 | 0.00% | Shares |
| ASSETMARK, INC | $407 | 22 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $18 | 1 | 0.00% | Shares |
| Activest Wealth Management | $18 | 1 | 0.00% | Shares |
| Parallel Advisors, LLC | $18 | 1 | 0.00% | Shares |
| Key Financial Inc | $18 | 1 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $18 | 1 | 0.00% | Shares |
| Pacer Advisors, Inc. | $17 | 942 | 0.00% | Shares |