MAZE — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $150,182,184 | 5,032,915 | 8.80% | Shares |
| TRV GP IV, LLC | $133,502,907 | 4,473,958 | 7.82% | Shares |
| ARCH Venture Management, LLC | $122,983,582 | 4,120,053 | 7.20% | Shares |
| Deep Track Capital, LP | $111,379,859 | 3,732,569 | 6.52% | Shares |
| BlackRock, Inc. | $104,524,775 | 3,502,841 | 6.12% | Shares |
| JANUS HENDERSON GROUP PLC | $85,280,271 | 2,858,876 | 4.99% | Shares |
| VANGUARD GROUP INC | $70,307,332 | 1,697,015 | 4.12% | Shares |
| Logos Global Management LP | $57,740,400 | 1,935,000 | 3.38% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $53,062,144 | 1,778,222 | 3.11% | Shares |
| a16z Capital Management, L.L.C. | $50,794,394 | 1,702,225 | 2.97% | Shares |
| Venrock Adviser, LLC | $47,804,695 | 1,602,034 | 2.80% | Shares |
| Alphabet Inc. | $41,435,317 | 1,388,583 | 2.43% | Shares |
| BRAIDWELL LP | $34,018,794 | 1,140,040 | 1.99% | Shares |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $33,057,170 | 1,107,814 | 1.94% | Shares |
| FMR LLC | $31,539,649 | 1,056,959 | 1.85% | Shares |
| General Catalyst Group Management, LLC | $30,911,554 | 1,035,910 | 1.81% | Shares |
| STATE STREET CORP | $29,766,385 | 997,533 | 1.74% | Shares |
| Driehaus Capital Management LLC | $28,493,798 | 954,886 | 1.67% | Shares |
| TRV GP V, LLC | $28,371,872 | 950,800 | 1.66% | Shares |
| JPMORGAN CHASE & CO | $27,995,382 | 964,011 | 1.64% | Shares |
| MARSHALL WACE, LLP | $27,290,827 | 914,572 | 1.60% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $25,608,436 | 858,054 | 1.50% | Shares |
| CITADEL ADVISORS LLC | $25,443,852 | 852,676 | 1.49% | Shares |
| Casdin Capital, LLC | $25,180,693 | 843,857 | 1.47% | Shares |
| ArrowMark Colorado Holdings LLC | $22,898,709 | 767,383 | 1.34% | Shares |
| Woodline Partners LP | $21,968,685 | 736,216 | 1.29% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $12,460,110 | 417,564 | 0.73% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $11,730,313 | 393,107 | 0.69% | Shares |
| Aberdeen Group plc | $11,451,786 | 383,773 | 0.67% | Shares |
| Ikarian Capital, LLC | $11,309,331 | 378,999 | 0.66% | Shares |
| HHLR ADVISORS, LTD. | $10,922,276 | 366,028 | 0.64% | Shares |
| ADAR1 Capital Management, LLC | $10,123,996 | 339,276 | 0.59% | Shares |
| Squadron Capital Management LLC | $9,996,400 | 335,000 | 0.59% | Shares |
| BANK OF AMERICA CORP /DE/ | $9,585,414 | 321,227 | 0.56% | Shares |
| NORTHERN TRUST CORP | $8,795,101 | 294,742 | 0.52% | Shares |
| GOLDMAN SACHS GROUP INC | $8,747,417 | 293,144 | 0.51% | Shares |
| Candriam S.C.A. | $8,166,266 | 273,932 | 0.48% | Shares |
| Hudson Bay Capital Management LP | $8,056,800 | 270,000 | 0.47% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,775,289 | 260,566 | 0.46% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $7,400,320 | 248,000 | 0.43% | Shares |
| Mass General Brigham, Inc | $7,161,421 | 239,994 | 0.42% | Shares |
| AMERIPRISE FINANCIAL INC | $6,786,363 | 227,425 | 0.40% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,562,950 | 219,938 | 0.38% | Shares |
| RTW INVESTMENTS, LP | $6,326,080 | 212,000 | 0.37% | Shares |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $5,796,288 | 199,872 | 0.34% | Shares |
| TWO SIGMA INVESTMENTS, LP | $5,757,688 | 192,952 | 0.34% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $5,635,493 | 188,857 | 0.33% | Shares |
| ExodusPoint Capital Management, LP | $5,468,598 | 183,264 | 0.32% | Shares |
| SummitTX Capital, L.P. | $5,260,523 | 176,291 | 0.31% | Shares |
| HighVista Strategies LLC | $4,075,308 | 136,572 | 0.24% | Shares |
| MORGAN STANLEY | $4,033,413 | 135,168 | 0.24% | Shares |
| Qube Research & Technologies Ltd | $3,910,323 | 131,043 | 0.23% | Shares |
| Walleye Capital LLC | $3,819,699 | 128,006 | 0.22% | Shares |
| Exome Asset Management LLC | $3,422,409 | 114,692 | 0.20% | Shares |
| Ensign Peak Advisors, Inc | $3,033,057 | 101,644 | 0.18% | Shares |
| Alyeska Investment Group, L.P. | $2,984,000 | 100,000 | 0.17% | Shares |
| Bank of New York Mellon Corp | $2,912,025 | 97,588 | 0.17% | Shares |
| ALGERT GLOBAL LLC | $2,785,773 | 93,357 | 0.16% | Shares |
| UBS Group AG | $2,526,821 | 84,679 | 0.15% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $2,468,485 | 82,724 | 0.14% | Shares |
| Trexquant Investment LP | $2,436,973 | 81,668 | 0.14% | Shares |
| FRANKLIN RESOURCES INC | $2,393,645 | 80,216 | 0.14% | Shares |
| Nuveen, LLC | $2,341,485 | 78,468 | 0.14% | Shares |
| OSAIC HOLDINGS, INC. | $2,323,044 | 77,850 | 0.14% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $2,305,170 | 77,251 | 0.13% | Shares |
| XTX Topco Ltd | $2,247,459 | 75,317 | 0.13% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $2,219,617 | 74,384 | 0.13% | Shares |
| RAYMOND JAMES FINANCIAL INC | $1,979,974 | 66,353 | 0.12% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1,953,565 | 65,468 | 0.11% | Shares |
| DAFNA Capital Management LLC | $1,939,600 | 65,000 | 0.11% | Shares |
| ALPS ADVISORS INC | $1,670,145 | 55,970 | 0.10% | Shares |
| Jump Financial, LLC | $1,406,329 | 47,129 | 0.08% | Shares |
| Swiss National Bank | $1,405,464 | 47,100 | 0.08% | Shares |
| FIRST TRUST ADVISORS LP | $1,379,413 | 46,227 | 0.08% | Shares |
| Propel Bio Management, LLC | $1,306,932 | 43,798 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $1,279,322 | 42,873 | 0.07% | Shares |
| ALLIANCEBERNSTEIN L.P. | $1,128,330 | 37,800 | 0.07% | Shares |
| DEUTSCHE BANK AG\ | $1,044,192 | 34,993 | 0.06% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $969,800 | 32,500 | 0.06% | Put option |
| WELLS FARGO & COMPANY/MN | $956,282 | 32,047 | 0.06% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $954,880 | 32,000 | 0.06% | Call option |
| CITIGROUP INC | $903,107 | 30,265 | 0.05% | Shares |
| Quadrature Capital Ltd | $896,602 | 30,047 | 0.05% | Shares |
| Invesco Ltd. | $846,620 | 28,372 | 0.05% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $810,485 | 27,161 | 0.05% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $777,720 | 26,063 | 0.05% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $711,386 | 23,840 | 0.04% | Shares |
| BARCLAYS PLC | $708,191 | 23,733 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $706,522 | 23,677 | 0.04% | Shares |
| TD Asset Management Inc | $661,672 | 22,174 | 0.04% | Shares |
| NOMURA HOLDINGS INC | $626,640 | 21,000 | 0.04% | Call option |
| NOMURA HOLDINGS INC | $626,640 | 21,000 | 0.04% | Put option |
| MetLife Investment Management, LLC | $623,626 | 20,899 | 0.04% | Shares |
| TWO SIGMA ADVISERS, LP | $613,164 | 14,800 | 0.04% | Shares |
| Balyasny Asset Management L.P. | $602,470 | 20,190 | 0.04% | Shares |
| Squarepoint Ops LLC | $579,911 | 19,434 | 0.03% | Shares |
| Verition Fund Management LLC | $543,118 | 18,201 | 0.03% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $490,450 | 16,436 | 0.03% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $489,436 | 16,402 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $484,840 | 16,248 | 0.03% | Shares |
| Legal & General Group Plc | $470,905 | 15,781 | 0.03% | Shares |
| AXQ CAPITAL, LP | $453,359 | 15,193 | 0.03% | Shares |
| Russell Investments Group, Ltd. | $432,919 | 14,508 | 0.03% | Shares |
| Y-Intercept (Hong Kong) Ltd | $428,801 | 14,370 | 0.03% | Shares |
| China Universal Asset Management Co., Ltd. | $412,031 | 13,808 | 0.02% | Shares |
| Virtus Investment Advisers, LLC | $405,973 | 13,605 | 0.02% | Shares |
| Verdad Advisers, LP | $376,521 | 12,618 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $375,984 | 12,600 | 0.02% | Call option |
| Congress Wealth Management LLC / DE / | $370,983 | 30,235 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $370,016 | 12,400 | 0.02% | Shares |
| Jain Global LLC | $365,182 | 12,238 | 0.02% | Shares |
| D. E. Shaw & Co., Inc. | $358,647 | 12,019 | 0.02% | Shares |
| Entropy Technologies, LP | $337,998 | 11,327 | 0.02% | Shares |
| Engineers Gate Manager LP | $332,507 | 11,143 | 0.02% | Shares |
| Vanguard Global Advisers, LLC | $329,881 | 11,055 | 0.02% | Shares |
| PROFUND ADVISORS LLC | $328,986 | 11,025 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $310,545 | 10,407 | 0.02% | Shares |
| EntryPoint Capital, LLC | $292,850 | 9,814 | 0.02% | Shares |
| Falcon Wealth Planning | $287,359 | 9,630 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $286,464 | 9,600 | 0.02% | Put option |
| CANADA PENSION PLAN INVESTMENT BOARD | $271,544 | 9,100 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $256,445 | 8,594 | 0.02% | Shares |
| Rafferty Asset Management, LLC | $241,018 | 8,077 | 0.01% | Shares |
| Creative Planning | $240,868 | 8,072 | 0.01% | Shares |
| State of New Jersey Common Pension Fund D | $226,545 | 7,592 | 0.01% | Shares |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $222,756 | 7,465 | 0.01% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $208,134 | 6,975 | 0.01% | Shares |
| Persistent Asset Partners Ltd | $200,197 | 6,709 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $174,504 | 5,848 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $158,152 | 5,300 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $95,548 | 3,202 | 0.01% | Shares |
| Caitong International Asset Management Co., Ltd | $93,429 | 3,131 | 0.01% | Shares |
| Quantbot Technologies LP | $79,732 | 2,672 | 0.00% | Shares |
| T. Rowe Price Investment Management, Inc. | $77,694 | 2,603,682 | 0.00% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $73,854 | 2,475 | 0.00% | Shares |
| CWM, LLC | $63,969 | 2,143 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $61,232 | 2,052 | 0.00% | Shares |
| Mitsubishi UFJ Asset Management Co., Ltd. | $47,744 | 1,600 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $40,493 | 1,357 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $34,793 | 1,166 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $32,000 | 1,072 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $30,467 | 1,021 | 0.00% | Shares |
| State of Wyoming | $24,260 | 813 | 0.00% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $19,545 | 655 | 0.00% | Shares |
| BESSEMER GROUP INC | $14,377 | 481,790 | 0.00% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $12,746 | 427 | 0.00% | Shares |
| IFP Advisors, Inc | $9,788 | 328 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $9,512 | 326 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $8,325 | 279 | 0.00% | Shares |
| Sterling Capital Management LLC | $6,624 | 222 | 0.00% | Shares |
| Aster Capital Management (DIFC) Ltd | $6,595 | 221 | 0.00% | Shares |
| Versant Capital Management, Inc | $5,490 | 202 | 0.00% | Shares |
| GAMMA Investing LLC | $5,073 | 170 | 0.00% | Shares |
| Quarry LP | $4,924 | 165 | 0.00% | Shares |
| Arax Advisory Partners | $4,595 | 154 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $4,446 | 149 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $3,965 | 132,870 | 0.00% | Shares |
| Torren Management, LLC | $3,343 | 112 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $2,559 | 90 | 0.00% | Shares |
| US BANCORP \DE\ | $2,387 | 80 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $1,492 | 50 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $955 | 32 | 0.00% | Shares |
| Cornerstone Financial Management LLC | $836 | 28 | 0.00% | Shares |
| SIGNATUREFD, LLC | $507 | 17 | 0.00% | Shares |
| Jackson Creek Investment Advisors LLC | $494 | 18,345 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $358 | 12 | 0.00% | Shares |
| Fortitude Family Office, LLC | $328 | 11 | 0.00% | Shares |
| Essential Partners LLC | $209 | 7 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $179 | 6 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $149 | 5 | 0.00% | Shares |
| Allworth Financial LP | $60 | 2 | 0.00% | Shares |
| Global Retirement Partners, LLC | $30 | 1 | 0.00% | Shares |
| Covestor Ltd | $0 | 12 | 0.00% | Shares |