RAPP — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $298,894,493 | 7,172,894 | 13.99% | Shares |
| TRV GP V, LLC | $261,709,477 | 6,280,525 | 12.25% | Shares |
| ARCH Venture Management, LLC | $155,376,512 | 3,728,738 | 7.27% | Shares |
| Capital International Investors | $121,757,990 | 2,921,958 | 5.70% | Shares |
| GOLDMAN SACHS GROUP INC | $121,278,410 | 2,910,449 | 5.68% | Shares |
| BlackRock, Inc. | $112,500,083 | 2,699,786 | 5.27% | Shares |
| Cormorant Asset Management, LP | $110,738,900 | 2,657,521 | 5.18% | Shares |
| Sofinnova Investments, Inc. | $79,356,681 | 1,904,408 | 3.71% | Shares |
| JOHNSON & JOHNSON | $74,360,823 | 1,784,517 | 3.48% | Shares |
| Polar Capital Holdings Plc | $67,026,778 | 1,608,514 | 3.14% | Shares |
| BAKER BROS. ADVISORS LP | $64,467,240 | 1,547,090 | 3.02% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $56,109,155 | 1,346,512 | 2.63% | Shares |
| VANGUARD GROUP INC | $55,150,747 | 1,817,757 | 2.58% | Shares |
| TRV GP VI, LLC | $40,387,314 | 969,218 | 1.89% | Shares |
| STATE STREET CORP | $34,115,729 | 818,712 | 1.60% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $33,068,458 | 793,453 | 1.55% | Shares |
| PERCEPTIVE ADVISORS LLC | $32,225,161 | 773,342 | 1.51% | Shares |
| Vestal Point Capital, LP | $30,419,100 | 730,000 | 1.42% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $28,751,317 | 918,866 | 1.35% | Shares |
| Siren, L.L.C. | $26,730,013 | 641,469 | 1.25% | Shares |
| Capital World Investors | $22,987,547 | 551,657 | 1.08% | Shares |
| ALLIANCEBERNSTEIN L.P. | $21,695,985 | 693,384 | 1.02% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $15,087,064 | 362,114 | 0.71% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $14,998,866 | 359,944 | 0.70% | Shares |
| Candriam S.C.A. | $14,472,638 | 347,650 | 0.68% | Shares |
| Sio Capital Management, LLC | $12,820,067 | 307,657 | 0.60% | Shares |
| MORGAN STANLEY | $12,401,492 | 297,612 | 0.58% | Shares |
| NORTHERN TRUST CORP | $11,555,299 | 277,305 | 0.54% | Shares |
| KENNEDY CAPITAL MANAGEMENT LLC | $10,450,628 | 250,795 | 0.49% | Shares |
| Burkehill Global Management, LP | $10,417,500 | 250,000 | 0.49% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $10,284,781 | 246,815 | 0.48% | Shares |
| ALGERT GLOBAL LLC | $9,326,663 | 223,822 | 0.44% | Shares |
| Invesco Ltd. | $8,968,884 | 215,236 | 0.42% | Shares |
| D. E. Shaw & Co., Inc. | $8,952,008 | 214,831 | 0.42% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $8,681,236 | 208,333 | 0.41% | Shares |
| Ensign Peak Advisors, Inc | $6,898,302 | 165,546 | 0.32% | Shares |
| MILLENNIUM MANAGEMENT LLC | $6,455,016 | 154,908 | 0.30% | Shares |
| UBS Group AG | $6,299,420 | 151,174 | 0.29% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $6,250,500 | 150,000 | 0.29% | Shares |
| Artia Global Partners LP | $5,771,628 | 138,508 | 0.27% | Shares |
| Swedbank AB | $4,892,058 | 117,400 | 0.23% | Shares |
| Nuveen, LLC | $4,307,053 | 103,361 | 0.20% | Shares |
| Walleye Capital LLC | $4,257,132 | 102,163 | 0.20% | Shares |
| Woodline Partners LP | $4,064,367 | 97,537 | 0.19% | Shares |
| TD Asset Management Inc | $3,828,556 | 91,878 | 0.18% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $3,624,790 | 86,988 | 0.17% | Shares |
| PRUDENTIAL FINANCIAL INC | $3,620,498 | 86,885 | 0.17% | Shares |
| CITADEL ADVISORS LLC | $3,435,358 | 82,442 | 0.16% | Shares |
| Bank of New York Mellon Corp | $3,426,191 | 82,222 | 0.16% | Shares |
| ORBIMED ADVISORS LLC | $3,192,589 | 76,616 | 0.15% | Shares |
| BANK OF AMERICA CORP /DE/ | $3,170,087 | 76,076 | 0.15% | Shares |
| DAFNA Capital Management LLC | $3,125,250 | 75,000 | 0.15% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2,903,649 | 69,682 | 0.14% | Shares |
| STEMPOINT CAPITAL LP | $2,774,472 | 66,582 | 0.13% | Shares |
| AMERICAN CENTURY COMPANIES INC | $2,740,386 | 65,764 | 0.13% | Shares |
| XTX Topco Ltd | $2,560,246 | 61,441 | 0.12% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $2,439,237 | 58,537 | 0.11% | Shares |
| Allspring Global Investments Holdings, LLC | $2,394,692 | 57,468 | 0.11% | Shares |
| JANE STREET GROUP, LLC | $2,321,228 | 55,705 | 0.11% | Shares |
| Russell Investments Group, Ltd. | $2,310,936 | 55,458 | 0.11% | Shares |
| Swiss National Bank | $2,300,184 | 55,200 | 0.11% | Shares |
| Trexquant Investment LP | $2,247,555 | 53,937 | 0.11% | Shares |
| ALPS ADVISORS INC | $2,010,286 | 48,243 | 0.09% | Shares |
| Susquehanna Portfolio Strategies, LLC | $1,665,883 | 39,978 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $1,550,030 | 37,198 | 0.07% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1,354,233 | 32,499 | 0.06% | Shares |
| DEUTSCHE BANK AG\ | $1,342,274 | 32,212 | 0.06% | Shares |
| WELLS FARGO & COMPANY/MN | $1,340,566 | 32,171 | 0.06% | Shares |
| Integrated Quantitative Investments LLC | $1,266,185 | 30,386 | 0.06% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $1,102,338 | 26,454 | 0.05% | Shares |
| TWO SIGMA INVESTMENTS, LP | $1,019,665 | 24,470 | 0.05% | Shares |
| CITIGROUP INC | $1,015,623 | 24,373 | 0.05% | Shares |
| Ellsworth Advisors, LLC | $979,842 | 24,539 | 0.05% | Shares |
| Creative Planning | $954,993 | 22,918 | 0.04% | Shares |
| Legal & General Group Plc | $939,867 | 22,555 | 0.04% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $920,949 | 22,101 | 0.04% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $919,032 | 22,055 | 0.04% | Shares |
| Engineers Gate Manager LP | $888,154 | 21,314 | 0.04% | Shares |
| Y-Intercept (Hong Kong) Ltd | $799,606 | 19,189 | 0.04% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $772,228 | 18,532 | 0.04% | Shares |
| MetLife Investment Management, LLC | $750,435 | 18,009 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $718,391 | 17,240 | 0.03% | Shares |
| SEI INVESTMENTS CO | $678,971 | 16,294 | 0.03% | Shares |
| JPMORGAN CHASE & CO | $669,021 | 16,564 | 0.03% | Shares |
| BARCLAYS PLC | $624,800 | 14,994 | 0.03% | Shares |
| AMERIPRISE FINANCIAL INC | $612,382 | 14,696 | 0.03% | Shares |
| OPTIMIZE FINANCIAL INC. | $608,632 | 14,606 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $594,048 | 14,256 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $587,880 | 14,108 | 0.03% | Shares |
| PSP Research LLC | $583,380 | 14,000 | 0.03% | Shares |
| VARCOV Co. | $537,335 | 12,895 | 0.03% | Shares |
| China Universal Asset Management Co., Ltd. | $450,536 | 10,812 | 0.02% | Shares |
| Allianz Asset Management GmbH | $445,869 | 10,700 | 0.02% | Shares |
| JANUS HENDERSON GROUP PLC | $432,768 | 13,800 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $429,201 | 10,300 | 0.02% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $424,034 | 10,176 | 0.02% | Shares |
| CATALYST PRIVATE WEALTH, LLC | $416,700 | 10,000 | 0.02% | Shares |
| STIFEL FINANCIAL CORP | $407,243 | 9,773 | 0.02% | Shares |
| CLEAR WAVE WEALTH MANAGEMENT LLC | $395,865 | 9,500 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $376,447 | 9,034 | 0.02% | Shares |
| State of New Jersey Common Pension Fund D | $370,321 | 8,887 | 0.02% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $362,529 | 8,700 | 0.02% | Call option |
| Virtus Investment Advisers, LLC | $355,070 | 8,521 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $348,820 | 8,371 | 0.02% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $343,986 | 8,255 | 0.02% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $316,025 | 7,584 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $302,483 | 7,259 | 0.01% | Shares |
| AlphaCentric Advisors LLC | $272,147 | 6,531 | 0.01% | Shares |
| Quadrature Capital Ltd | $264,980 | 6,359 | 0.01% | Shares |
| PROFUND ADVISORS LLC | $264,938 | 6,358 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $245,853 | 5,900 | 0.01% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $241,686 | 5,800 | 0.01% | Put option |
| ProShare Advisors LLC | $232,519 | 5,580 | 0.01% | Shares |
| Pictet Asset Management Holding SA | $216,601 | 5,198 | 0.01% | Shares |
| JANE STREET GROUP, LLC | $208,350 | 5,000 | 0.01% | Put option |
| Sandia Investment Management LP | $182,040 | 6,000 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $124,010 | 2,976 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $115,843 | 2,780 | 0.01% | Shares |
| MEEDER ASSET MANAGEMENT INC | $115,593 | 2,774 | 0.01% | Shares |
| AlphaQuest LLC | $113,896 | 3,754 | 0.01% | Shares |
| STRS OHIO | $108,342 | 2,600 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $89,132 | 2,139 | 0.00% | Shares |
| Aquatic Capital Management LLC | $88,007 | 2,112 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $79,923 | 1,918 | 0.00% | Shares |
| State of Wyoming | $65,005 | 1,560 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $47,000 | 1,147 | 0.00% | Shares |
| CWM, LLC | $46,153 | 1,475 | 0.00% | Shares |
| Tidemark, LLC | $45,337 | 1,088 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $42,128 | 1,011 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $32,814 | 787,446 | 0.00% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $32,128 | 771 | 0.00% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $20,710 | 497 | 0.00% | Shares |
| GAMMA Investing LLC | $17,001 | 408 | 0.00% | Shares |
| T. Rowe Price Investment Management, Inc. | $16,385 | 393,200 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $15,668 | 376 | 0.00% | Shares |
| FEDERATED HERMES, INC. | $10,001 | 240 | 0.00% | Shares |
| Stone House Investment Management, LLC | $8,792 | 211 | 0.00% | Shares |
| SIGNATUREFD, LLC | $8,542 | 205 | 0.00% | Shares |
| MassMutual Private Wealth & Trust, FSB | $6,792 | 163 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $6,125 | 147 | 0.00% | Shares |
| Sterling Capital Management LLC | $5,875 | 141 | 0.00% | Shares |
| Larson Financial Group LLC | $5,459 | 131 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $5,167 | 124 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $4,845 | 123 | 0.00% | Shares |
| Aster Capital Management (DIFC) Ltd | $4,500 | 108 | 0.00% | Shares |
| Arax Advisory Partners | $2,251 | 54 | 0.00% | Shares |
| Optiver Holding B.V. | $2,250 | 54 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $2,209 | 53 | 0.00% | Shares |
| Cornerstone Financial Management LLC | $2,042 | 49 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $2,000 | 48 | 0.00% | Shares |
| True Wealth Design, LLC | $1,709 | 41 | 0.00% | Shares |
| Essential Partners LLC | $1,667 | 40 | 0.00% | Shares |
| Bare Financial Services, Inc | $1,625 | 39 | 0.00% | Shares |
| Versant Capital Management, Inc | $1,125 | 27 | 0.00% | Shares |
| Versant Capital Management, Inc | $907 | 27 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $875 | 21 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $833 | 20 | 0.00% | Shares |
| US BANCORP \DE\ | $583 | 14 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $344 | 11 | 0.00% | Shares |
| Allworth Financial LP | $292 | 7 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $291 | 7 | 0.00% | Shares |
| Ameritas Advisory Services, LLC | $208 | 5 | 0.00% | Shares |
| Lindbrook Capital, LLC | $150 | 15 | 0.00% | Shares |
| IFP Advisors, Inc | $125 | 3 | 0.00% | Shares |
| Global Retirement Partners, LLC | $83 | 2 | 0.00% | Shares |
| KBC Group NV | $40 | 962 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $39 | 957 | 0.00% | Shares |
| Covestor Ltd | $1 | 17 | 0.00% | Shares |