OPK — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Rubric Capital Management LP | $71,686,865 | 47,791,243 | 20.81% | Shares |
| BlackRock, Inc. | $55,468,342 | 36,978,893 | 16.10% | Shares |
| VANGUARD GROUP INC | $40,896,813 | 32,457,788 | 11.87% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $22,453,395 | 14,968,930 | 6.52% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $22,402,386 | 14,934,924 | 6.50% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $17,375,151 | 11,581,027 | 5.04% | Shares |
| STATE STREET CORP | $15,463,605 | 10,309,070 | 4.49% | Shares |
| GOLDMAN SACHS GROUP INC | $10,553,239 | 7,035,492 | 3.06% | Shares |
| UBS Group AG | $7,509,427 | 5,006,284 | 2.18% | Shares |
| Whitefort Capital Management, LP | $6,767,118 | 4,511,412 | 1.96% | Shares |
| NORTHERN TRUST CORP | $5,634,246 | 3,756,163 | 1.64% | Shares |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | $5,426,827 | 3,593,925 | 1.58% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5,395,470 | 3,596,980 | 1.57% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $4,059,353 | 2,706,235 | 1.18% | Shares |
| AWM Investment Company, Inc. | $3,165,000 | 2,110,000 | 0.92% | Shares |
| MORGAN STANLEY | $2,962,542 | 1,975,027 | 0.86% | Shares |
| CITADEL ADVISORS LLC | $2,131,383 | 1,420,922 | 0.62% | Shares |
| WASHINGTON GROWTH STRATEGIES LLC | $2,034,186 | 1,356,124 | 0.59% | Shares |
| Bank of New York Mellon Corp | $1,994,961 | 1,329,974 | 0.58% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $1,902,026 | 1,267,741 | 0.55% | Shares |
| Y.D. More Investments Ltd | $1,876,217 | 1,257,568 | 0.54% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $1,859,101 | 1,239,399 | 0.54% | Shares |
| OP Asset Management Ltd | $1,739,471 | 1,159,647 | 0.51% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $1,641,167 | 1,094,111 | 0.48% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1,442,226 | 961,484 | 0.42% | Shares |
| Clearstead Advisors, LLC | $1,324,932 | 883,288 | 0.38% | Shares |
| Nuveen, LLC | $1,294,553 | 863,035 | 0.38% | Shares |
| BANK OF AMERICA CORP /DE/ | $1,193,573 | 795,716 | 0.35% | Shares |
| Swiss National Bank | $1,142,183 | 761,455 | 0.33% | Shares |
| Invesco Ltd. | $1,027,615 | 685,076 | 0.30% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $935,342 | 623,561 | 0.27% | Shares |
| PFG Investments, LLC | $915,737 | 610,491 | 0.27% | Shares |
| Kovack Advisors, Inc. | $804,303 | 536,202 | 0.23% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $769,327 | 674,848 | 0.22% | Shares |
| RHUMBLINE ADVISERS | $748,287 | 498,861 | 0.22% | Shares |
| VAN ECK ASSOCIATES CORP | $657,968 | 438,645 | 0.19% | Shares |
| COMMONWEALTH EQUITY SERVICES, LLC | $647,840 | 431,894 | 0.19% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $618,077 | 412,051 | 0.18% | Shares |
| DEUTSCHE BANK AG\ | $597,905 | 398,603 | 0.17% | Shares |
| ALGERT GLOBAL LLC | $595,545 | 397,030 | 0.17% | Shares |
| WELLS FARGO & COMPANY/MN | $531,059 | 354,039 | 0.15% | Shares |
| Legal & General Group Plc | $520,181 | 346,787 | 0.15% | Shares |
| ALLIANCEBERNSTEIN L.P. | $504,655 | 442,680 | 0.15% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $441,020 | 294,013 | 0.13% | Shares |
| ROYAL BANK OF CANADA | $435,000 | 289,812 | 0.13% | Shares |
| XTX Topco Ltd | $429,260 | 286,173 | 0.12% | Shares |
| Assenagon Asset Management S.A. | $425,502 | 285,339 | 0.12% | Shares |
| Creative Planning | $369,098 | 246,065 | 0.11% | Shares |
| TUDOR INVESTMENT CORP ET AL | $367,232 | 244,821 | 0.11% | Shares |
| JANE STREET GROUP, LLC | $344,181 | 229,454 | 0.10% | Shares |
| MetLife Investment Management, LLC | $340,199 | 226,799 | 0.10% | Shares |
| Russell Investments Group, Ltd. | $323,730 | 215,820 | 0.09% | Shares |
| CITIGROUP INC | $299,737 | 199,824 | 0.09% | Shares |
| HSBC HOLDINGS PLC | $298,949 | 199,966 | 0.09% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $278,346 | 185,564 | 0.08% | Shares |
| Vanguard Global Advisers, LLC | $272,649 | 181,766 | 0.08% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $264,390 | 176,260 | 0.08% | Shares |
| TWO SIGMA INVESTMENTS, LP | $263,702 | 175,801 | 0.08% | Shares |
| GAMCO INVESTORS, INC. ET AL | $262,500 | 175,000 | 0.08% | Shares |
| GABELLI FUNDS LLC | $255,000 | 170,000 | 0.07% | Shares |
| FIFTH THIRD BANCORP | $255,000 | 170,000 | 0.07% | Shares |
| JPMORGAN CHASE & CO | $254,141 | 168,305 | 0.07% | Shares |
| IEQ CAPITAL, LLC | $254,138 | 169,425 | 0.07% | Shares |
| TWO SIGMA ADVISERS, LP | $240,913 | 191,201 | 0.07% | Shares |
| JANUS HENDERSON GROUP PLC | $236,230 | 206,314 | 0.07% | Shares |
| 360 Financial, Inc. | $225,450 | 150,300 | 0.07% | Shares |
| Point72 Asset Management, L.P. | $217,851 | 145,234 | 0.06% | Shares |
| Teton Advisors, LLC | $210,000 | 140,000 | 0.06% | Shares |
| Police & Firemen's Retirement System of New Jersey | $198,694 | 132,463 | 0.06% | Shares |
| Teton Advisors, Inc. | $187,440 | 142,000 | 0.05% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $178,698 | 119,132 | 0.05% | Shares |
| Glenmede Investment Management, LP | $175,790 | 113,413 | 0.05% | Shares |
| HIGHLINE WEALTH PARTNERS LLC | $175,020 | 116,680 | 0.05% | Shares |
| State of Wyoming | $174,734 | 116,489 | 0.05% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $171,452 | 114,301 | 0.05% | Shares |
| GLENMEDE TRUST CO NA | $169,125 | 112,750 | 0.05% | Shares |
| Vanguard Investments Australia, Ltd. | $166,437 | 110,958 | 0.05% | Shares |
| Headlands Technologies LLC | $161,984 | 107,989 | 0.05% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $157,088 | 104,725 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $156,150 | 104,100 | 0.05% | Call option |
| U.S. Capital Wealth Advisors, LLC | $151,918 | 133,261 | 0.04% | Shares |
| COMERICA BANK | $151,200 | 120,000 | 0.04% | Shares |
| ZAZOVE ASSOCIATES LLC | $150,000 | 100,000 | 0.04% | Shares |
| BARCLAYS PLC | $149,395 | 99,596 | 0.04% | Shares |
| AMERIPRISE FINANCIAL INC | $141,092 | 94,061 | 0.04% | Shares |
| Arax Advisory Partners | $140,425 | 93,616 | 0.04% | Shares |
| Cerity Partners LLC | $136,651 | 91,099 | 0.04% | Shares |
| KLP KAPITALFORVALTNING AS | $136,050 | 90,700 | 0.04% | Shares |
| RPg Family Wealth Advisory, LLC | $132,928 | 88,619 | 0.04% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $128,825 | 85,883 | 0.04% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $115,212 | 76,808 | 0.03% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $113,392 | 83,994 | 0.03% | Shares |
| Cubist Systematic Strategies, LLC | $111,798 | 72,127 | 0.03% | Shares |
| MILLENNIUM MANAGEMENT LLC | $108,452 | 72,301 | 0.03% | Shares |
| OSAIC HOLDINGS, INC. | $104,349 | 69,567 | 0.03% | Shares |
| PRUDENTIAL FINANCIAL INC | $103,464 | 68,976 | 0.03% | Shares |
| Cascade Financial Partners, LLC | $99,735 | 66,490 | 0.03% | Shares |
| Pictet Asset Management Holding SA | $98,243 | 65,495 | 0.03% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $95,556 | 63,704 | 0.03% | Shares |
| Cetera Investment Advisers | $91,421 | 60,947 | 0.03% | Shares |
| CITADEL ADVISORS LLC | $91,050 | 60,700 | 0.03% | Put option |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $89,250 | 59,500 | 0.03% | Call option |
| KESTRA PRIVATE WEALTH SERVICES, LLC | $87,675 | 58,450 | 0.03% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $86,292 | 57,528 | 0.03% | Shares |
| Private Advisor Group, LLC | $82,952 | 55,301 | 0.02% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $82,710 | 55,140 | 0.02% | Shares |
| CWM, LLC | $79,611 | 69,834 | 0.02% | Shares |
| ProShare Advisors LLC | $79,149 | 52,766 | 0.02% | Shares |
| FIRST MANHATTAN CO. LLC. | $78,225 | 52,150 | 0.02% | Shares |
| TRANSCEND CAPITAL ADVISORS, LLC | $77,775 | 51,850 | 0.02% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $77,285 | 51,523 | 0.02% | Shares |
| GROUP ONE TRADING LLC | $75,820 | 50,547 | 0.02% | Shares |
| Mariner, LLC | $75,729 | 50,486 | 0.02% | Shares |
| Farmers National Bank | $75,450 | 50,300 | 0.02% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $65,435 | 43,623 | 0.02% | Shares |
| BRIGHTON JONES LLC | $64,730 | 43,153 | 0.02% | Shares |
| Squarepoint Ops LLC | $62,387 | 41,591 | 0.02% | Shares |
| HOLLENCREST CAPITAL MANAGEMENT | $60,000 | 40,000 | 0.02% | Shares |
| Caitong International Asset Management Co., Ltd | $59,802 | 39,868 | 0.02% | Shares |
| STRS OHIO | $58,350 | 38,900 | 0.02% | Shares |
| XPONANCE LLC | $58,122 | 38,748 | 0.02% | Shares |
| PNC Financial Services Group, Inc. | $55,500 | 37,000 | 0.02% | Shares |
| Altshuler Shaham Ltd | $53,698 | 35,992 | 0.02% | Shares |
| Waverly Advisors, LLC | $51,495 | 34,330 | 0.01% | Shares |
| Orion Portfolio Solutions, LLC | $49,800 | 30,000 | 0.01% | Shares |
| Operose Advisors LLC | $48,000 | 32,000 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $47,834 | 31,889 | 0.01% | Shares |
| CHOREO, LLC | $47,211 | 31,474 | 0.01% | Shares |
| HighTower Advisors, LLC | $46,827 | 31,218 | 0.01% | Shares |
| IPG Investment Advisors LLC | $45,000 | 30,000 | 0.01% | Shares |
| EP Wealth Advisors, LLC | $44,583 | 29,722 | 0.01% | Shares |
| Swiss Life Asset Management Ltd | $42,732 | 28,488 | 0.01% | Shares |
| LPL Financial LLC | $42,221 | 28,147 | 0.01% | Shares |
| PBMares Wealth Management LLC | $41,883 | 27,021 | 0.01% | Shares |
| World Investment Advisors | $41,234 | 36,170 | 0.01% | Shares |
| Schonfeld Strategic Advisors LLC | $40,459 | 26,973 | 0.01% | Shares |
| Apella Capital, LLC | $40,261 | 27,021 | 0.01% | Shares |
| Arrow Financial Corp | $38,250 | 25,500 | 0.01% | Shares |
| JANE STREET GROUP, LLC | $38,250 | 25,500 | 0.01% | Call option |
| DIVERSIFY WEALTH MANAGEMENT, LLC | $37,200 | 30,000 | 0.01% | Shares |
| Diversify Advisory Services, LLC | $37,200 | 30,000 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $37,078 | 24,719 | 0.01% | Shares |
| SIMPLEX TRADING, LLC | $34,849 | 23,233 | 0.01% | Shares |
| SIH Partners, LLLP | $34,475 | 22,983 | 0.01% | Shares |
| Vanguard Personalized Indexing Management, LLC | $34,469 | 22,979 | 0.01% | Shares |
| CIBC WORLD MARKETS CORP | $34,304 | 27,225 | 0.01% | Shares |
| Graham Capital Management, L.P. | $34,251 | 22,834 | 0.01% | Shares |
| CIBC Bancorp USA Inc. | $33,374 | 22,249 | 0.01% | Shares |
| CIBC Asset Management Inc | $32,877 | 21,918 | 0.01% | Shares |
| RAYMOND JAMES FINANCIAL INC | $32,869 | 21,912 | 0.01% | Shares |
| Spartan Wealth Advisory Services LLC | $30,000 | 20,000 | 0.01% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $29,347 | 19,181 | 0.01% | Shares |
| CUMBERLAND ADVISORS INC | $29,250 | 19,500 | 0.01% | Shares |
| Westmount Partners, LLC | $27,825 | 18,550 | 0.01% | Shares |
| TWO SIGMA SECURITIES, LLC | $27,405 | 18,270 | 0.01% | Shares |
| SHUFRO ROSE & CO LLC | $25,500 | 17,000 | 0.01% | Shares |
| Caprock Group, LLC | $25,155 | 16,770 | 0.01% | Shares |
| COMMONS CAPITAL, LLC | $24,450 | 16,300 | 0.01% | Shares |
| Sigma Planning Corp | $23,711 | 15,807 | 0.01% | Shares |
| FMR LLC | $23,004 | 15,336 | 0.01% | Shares |
| AXQ CAPITAL, LP | $22,982 | 15,321 | 0.01% | Shares |
| SAX WEALTH ADVISORS, LLC | $22,857 | 20,050 | 0.01% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $22,235 | 14,823 | 0.01% | Shares |
| Colony Family Offices, LLC | $22,094 | 14,729 | 0.01% | Shares |
| Merit Financial Group, LLC | $21,910 | 14,606 | 0.01% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $21,332 | 14,221 | 0.01% | Shares |
| GTS SECURITIES LLC | $21,141 | 14,094 | 0.01% | Shares |
| Key Financial Inc | $19,875 | 13,250 | 0.01% | Shares |
| Sanctuary Advisors, LLC | $18,587 | 12,391 | 0.01% | Shares |
| Pathstone Holdings, LLC | $18,575 | 12,383 | 0.01% | Shares |
| Focus Partners Wealth | $18,094 | 12,062 | 0.01% | Shares |
| Point72 (DIFC) Ltd | $17,747 | 11,450 | 0.01% | Shares |
| TRAPHAGEN INVESTMENT ADVISORS LLC | $17,520 | 11,680 | 0.01% | Shares |
| Compound Planning, Inc. | $17,073 | 11,382 | 0.00% | Shares |
| Corient Private Wealth LP | $17,055 | 11,370 | 0.00% | Shares |
| EVERGREEN CAPITAL MANAGEMENT LLC | $16,809 | 11,206 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $16,665 | 11,110 | 0.00% | Shares |
| Mill Creek Capital Advisors, LLC | $16,397 | 14,383 | 0.00% | Shares |
| Stillwater Capital Advisors, LLC | $15,848 | 10,565 | 0.00% | Shares |
| SEI INVESTMENTS CO | $15,245 | 10,163 | 0.00% | Shares |
| DIVERSIFIED TRUST CO | $15,183 | 10,122 | 0.00% | Shares |
| Greenbush Financial Group, LLC | $15,000 | 10,000 | 0.00% | Shares |
| MRP Capital Investments, LLC | $15,000 | 10,000 | 0.00% | Shares |
| KLCM Advisors, Inc. | $15,000 | 10,000 | 0.00% | Shares |
| HBK Sorce Advisory LLC | $14,927 | 11,057 | 0.00% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $14,917 | 9,624 | 0.00% | Shares |
| Quantbot Technologies LP | $14,267 | 9,511 | 0.00% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $13,320 | 8,880 | 0.00% | Shares |
| Aventura Private Wealth, LLC | $12,600 | 8,400 | 0.00% | Shares |
| Sterling Capital Management LLC | $12,183 | 8,122 | 0.00% | Shares |
| Formidable Asset Management, LLC | $11,737 | 10,296 | 0.00% | Shares |
| First Affirmative Financial Network | $11,523 | 10,108 | 0.00% | Shares |
| Allworth Financial LP | $10,788 | 7,192 | 0.00% | Shares |
| Raiffeisen Bank International AG | $9,782 | 6,521 | 0.00% | Call option |
| NATIONAL BANK OF CANADA /FI/ | $7,800 | 5,200 | 0.00% | Shares |
| FSA Wealth Management LLC | $6,123 | 3,950 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $5,591 | 3,727 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $5,111 | 3,408 | 0.00% | Shares |
| Optiver Holding B.V. | $4,840 | 3,227 | 0.00% | Shares |
| GABLES CAPITAL MANAGEMENT INC. | $4,500 | 3,000 | 0.00% | Shares |
| Smartleaf Asset Management LLC | $4,163 | 2,757 | 0.00% | Shares |
| Parallel Advisors, LLC | $3,974 | 2,649 | 0.00% | Shares |
| Essential Partners LLC | $3,800 | 2,533 | 0.00% | Shares |
| Moser Wealth Advisors, LLC | $3,157 | 2,392 | 0.00% | Shares |
| Glen Eagle Advisors, LLC | $3,150 | 2,100 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $3,000 | 2,000 | 0.00% | Shares |
| CoreCap Advisors, LLC | $2,400 | 1,600 | 0.00% | Shares |
| US BANCORP \DE\ | $2,352 | 1,568 | 0.00% | Shares |
| GAMMA Investing LLC | $2,001 | 1,334 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $1,934 | 1,289 | 0.00% | Shares |
| Godfrey Financial Associates, Inc. | $1,875 | 1,250 | 0.00% | Shares |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $1,840 | 1,227 | 0.00% | Shares |
| PFS Partners, LLC | $1,650 | 1,100 | 0.00% | Shares |
| Quarry LP | $1,430 | 953 | 0.00% | Shares |
| Salomon & Ludwin, LLC | $1,276 | 834 | 0.00% | Shares |
| True Wealth Design, LLC | $1,148 | 765 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $1,106 | 737 | 0.00% | Shares |
| Fortitude Family Office, LLC | $1,098 | 732 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $684 | 455,748 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $600 | 400 | 0.00% | Shares |
| IFP Advisors, Inc | $580 | 387 | 0.00% | Shares |
| PITTENGER & ANDERSON INC | $375 | 250 | 0.00% | Shares |
| SIGNATUREFD, LLC | $320 | 213 | 0.00% | Shares |
| Hilton Head Capital Partners, LLC | $300 | 200 | 0.00% | Shares |
| HARBOR INVESTMENT ADVISORY, LLC | $270 | 180 | 0.00% | Shares |
| SG Americas Securities, LLC | $171 | 113,848 | 0.00% | Shares |
| SALEM INVESTMENT COUNSELORS INC | $150 | 100 | 0.00% | Shares |
| Cambridge Investment Research Advisors, Inc. | $126 | 83,675 | 0.00% | Shares |
| Boreal Capital Management LLC | $104 | 69 | 0.00% | Shares |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $92 | 61,502 | 0.00% | Shares |
| CANADA LIFE ASSURANCE Co | $81 | 54,068 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $63 | 55 | 0.00% | Shares |
| Larson Financial Group LLC | $60 | 40 | 0.00% | Shares |
| RK Asset Management, LLC | $51 | 40,485 | 0.00% | Shares |
| SHELL ASSET MANAGEMENT CO | $26 | 16,596 | 0.00% | Shares |
| JPL Wealth Management, LLC | $24 | 16 | 0.00% | Shares |
| AMALGAMATED BANK | $16 | 10,934 | 0.00% | Shares |
| Dunhill Financial, LLC | $13 | 8 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $3 | 2 | 0.00% | Shares |
| Keating Financial Advisory Services, Inc. | $2 | 1 | 0.00% | Shares |
| Crewe Advisors LLC | $2 | 1 | 0.00% | Shares |
| LRI Investments, LLC | $2 | 1 | 0.00% | Shares |
| Guerra Advisors Inc | $2 | 1 | 0.00% | Shares |
| Covestor Ltd | $0 | 245 | 0.00% | Shares |
| FNY Investment Advisers, LLC | $0 | 2 | 0.00% | Call option |
| Centerpoint Advisors, LLC | $0 | 100 | 0.00% | Shares |
| Motiv8 Investments LLC | $0 | 300 | 0.00% | Shares |