SPRY — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $86,996,426 | 10,860,977 | 11.65% | Shares |
| Rubric Capital Management LP | $68,412,297 | 8,540,861 | 9.16% | Shares |
| ORBIMED ADVISORS LLC | $66,390,965 | 8,288,510 | 8.89% | Shares |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $60,105,534 | 7,503,812 | 8.05% | Shares |
| BlackRock, Inc. | $42,543,666 | 5,311,319 | 5.70% | Shares |
| VANGUARD GROUP INC | $40,881,877 | 3,509,174 | 5.48% | Shares |
| Tyro Capital Management LLC | $35,719,289 | 4,459,337 | 4.78% | Shares |
| Aberdeen Group plc | $33,406,738 | 4,170,629 | 4.47% | Shares |
| SR One Capital Management, LP | $32,143,353 | 4,012,903 | 4.30% | Shares |
| STATE STREET CORP | $29,882,290 | 3,730,623 | 4.00% | Shares |
| Capital World Investors | $22,066,997 | 2,754,931 | 2.96% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $20,453,759 | 2,553,528 | 2.74% | Shares |
| MILLENNIUM MANAGEMENT LLC | $19,231,505 | 2,400,937 | 2.58% | Shares |
| UBS Group AG | $15,536,629 | 1,939,654 | 2.08% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $13,612,279 | 1,699,017 | 1.82% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $12,828,047 | 1,601,504 | 1.72% | Shares |
| GENERAL AMERICAN INVESTORS CO INC | $9,075,698 | 1,133,046 | 1.22% | Shares |
| Third Point LLC | $8,010,000 | 1,000,000 | 1.07% | Shares |
| PEREGRINE CAPITAL MANAGEMENT LLC | $5,383,833 | 672,139 | 0.72% | Shares |
| Tejara Capital Ltd | $4,862,382 | 607,039 | 0.65% | Shares |
| ADAR1 Capital Management, LLC | $4,814,002 | 600,999 | 0.64% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4,540,300 | 566,829 | 0.61% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $4,416,842 | 551,416 | 0.59% | Shares |
| NORTHERN TRUST CORP | $4,398,003 | 549,064 | 0.59% | Shares |
| LEVIN CAPITAL STRATEGIES, L.P. | $4,397,210 | 548,965 | 0.59% | Shares |
| CITADEL ADVISORS LLC | $4,253,814 | 531,063 | 0.57% | Shares |
| Empire Life Investments Inc. | $3,779,567 | 471,856 | 0.51% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $3,731,388 | 464,681 | 0.50% | Shares |
| BANK OF AMERICA CORP /DE/ | $3,710,681 | 463,256 | 0.50% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $3,692,618 | 461,001 | 0.49% | Shares |
| FIL Ltd | $3,649,156 | 455,575 | 0.49% | Shares |
| JPMORGAN CHASE & CO | $3,109,986 | 363,316 | 0.42% | Shares |
| GOLDMAN SACHS GROUP INC | $3,049,967 | 380,770 | 0.41% | Shares |
| Eversept Partners, LP | $3,019,826 | 377,007 | 0.40% | Shares |
| K2 PRINCIPAL FUND, L.P. | $3,004,807 | 375,132 | 0.40% | Shares |
| INVESTMENT MANAGEMENT ASSOCIATES INC /ADV | $2,991,663 | 373,491 | 0.40% | Shares |
| FMR LLC | $2,796,806 | 349,164 | 0.37% | Shares |
| RAYMOND JAMES FINANCIAL INC | $2,551,850 | 318,583 | 0.34% | Shares |
| Trexquant Investment LP | $2,296,731 | 286,733 | 0.31% | Shares |
| Jump Financial, LLC | $2,044,152 | 255,200 | 0.27% | Shares |
| MORGAN STANLEY | $1,835,091 | 229,100 | 0.25% | Shares |
| FAS Wealth Partners, Inc. | $1,718,202 | 214,507 | 0.23% | Shares |
| Quinn Opportunity Partners LLC | $1,401,750 | 175,000 | 0.19% | Shares |
| Bank of New York Mellon Corp | $1,346,769 | 168,136 | 0.18% | Shares |
| DAFNA Capital Management LLC | $1,315,923 | 164,285 | 0.18% | Shares |
| Nuveen, LLC | $1,292,350 | 161,342 | 0.17% | Shares |
| Ishara Investments LP | $1,149,355 | 143,490 | 0.15% | Shares |
| Engineers Gate Manager LP | $1,116,746 | 139,419 | 0.15% | Shares |
| Steward Partners Investment Advisory, LLC | $1,030,086 | 128,600 | 0.14% | Shares |
| BARCLAYS PLC | $1,011,352 | 126,261 | 0.14% | Shares |
| AMERICAN ASSETS INC | $1,001,250 | 125,000 | 0.13% | Shares |
| Quantinno Capital Management LP | $996,676 | 124,429 | 0.13% | Shares |
| MARSHALL WACE, LLP | $990,949 | 123,714 | 0.13% | Shares |
| CenterBook Partners LP | $990,228 | 123,624 | 0.13% | Shares |
| MILLENNIUM MANAGEMENT LLC | $961,200 | 120,000 | 0.13% | Call option |
| DIMENSIONAL FUND ADVISORS LP | $925,339 | 115,523 | 0.12% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $922,752 | 115,200 | 0.12% | Call option |
| SEI INVESTMENTS CO | $838,190 | 104,643 | 0.11% | Shares |
| Parkman Healthcare Partners LLC | $822,627 | 102,700 | 0.11% | Shares |
| Swiss National Bank | $757,746 | 94,600 | 0.10% | Shares |
| Kodai Capital Management LP | $756,196 | 60,111 | 0.10% | Shares |
| Corient Private Wealth LP | $729,248 | 91,042 | 0.10% | Shares |
| CITIGROUP INC | $714,484 | 89,199 | 0.10% | Shares |
| VALLEY FORGE INVESTMENT CONSULTANTS INC ADV | $666,633 | 83,225 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $608,660 | 75,989 | 0.08% | Shares |
| Headlands Technologies LLC | $602,985 | 75,279 | 0.08% | Shares |
| AssuredPartners Investment Advisors, LLC | $586,816 | 73,260 | 0.08% | Shares |
| XTX Topco Ltd | $586,228 | 73,187 | 0.08% | Shares |
| Norman Fields, Gottscho Capital Management, LLC | $569,351 | 71,080 | 0.08% | Shares |
| Matisse Capital | $539,849 | 67,229 | 0.07% | Shares |
| DEUTSCHE BANK AG\ | $527,587 | 65,866 | 0.07% | Shares |
| DIKER MANAGEMENT LLC | $525,000 | 65,508 | 0.07% | Shares |
| Balyasny Asset Management L.P. | $517,911 | 64,658 | 0.07% | Shares |
| Rafferty Asset Management, LLC | $509,228 | 63,574 | 0.07% | Shares |
| WELLS FARGO & COMPANY/MN | $504,590 | 62,995 | 0.07% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $481,481 | 60,110 | 0.06% | Shares |
| ALLIANCEBERNSTEIN L.P. | $477,705 | 59,490 | 0.06% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $474,192 | 59,200 | 0.06% | Put option |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $467,888 | 58,413 | 0.06% | Shares |
| Coastal Bridge Advisors, LLC | $447,262 | 55,838 | 0.06% | Shares |
| ROYCE & ASSOCIATES LP | $432,732 | 54,024 | 0.06% | Shares |
| TWO SIGMA INVESTMENTS, LP | $419,724 | 52,400 | 0.06% | Shares |
| SCHULHOFF & CO INC | $409,711 | 51,150 | 0.05% | Shares |
| K2 PRINCIPAL FUND, L.P. | $384,480 | 48,000 | 0.05% | Call option |
| AlphaQuest LLC | $384,101 | 32,970 | 0.05% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $369,445 | 46,123 | 0.05% | Shares |
| TUDOR INVESTMENT CORP ET AL | $367,619 | 45,895 | 0.05% | Shares |
| Permanent Capital Management, LP | $347,498 | 43,383 | 0.05% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $323,508 | 40,388 | 0.04% | Shares |
| LETKO, BROSSEAU & ASSOCIATES INC | $320,801 | 40,050 | 0.04% | Shares |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | $317,028 | 39,579 | 0.04% | Shares |
| Legal & General Group Plc | $312,490 | 38,988 | 0.04% | Shares |
| Invesco Ltd. | $311,516 | 38,891 | 0.04% | Shares |
| MetLife Investment Management, LLC | $293,518 | 36,644 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $290,452 | 35,754 | 0.04% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $285,764 | 35,676 | 0.04% | Shares |
| Everstar Asset Management, LLC | $270,193 | 33,732 | 0.04% | Shares |
| VARCOV Co. | $263,889 | 32,945 | 0.04% | Shares |
| WINTON GROUP Ltd | $263,529 | 32,900 | 0.04% | Shares |
| PROFUND ADVISORS LLC | $257,914 | 32,199 | 0.03% | Shares |
| Verition Fund Management LLC | $246,308 | 30,750 | 0.03% | Shares |
| Cresset Asset Management, LLC | $241,518 | 30,152 | 0.03% | Shares |
| SECTORAL ASSET MANAGEMENT INC | $239,499 | 29,900 | 0.03% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $238,113 | 29,727 | 0.03% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $237,096 | 29,600 | 0.03% | Shares |
| ALLSTATE CORP | $236,704 | 29,551 | 0.03% | Shares |
| WOLVERINE TRADING, LLC | $235,866 | 24,266 | 0.03% | Shares |
| WOLVERINE TRADING, LLC | $218,700 | 22,500 | 0.03% | Call option |
| AXQ CAPITAL, LP | $214,195 | 26,741 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $212,545 | 26,535 | 0.03% | Shares |
| LPL Financial LLC | $209,734 | 26,184 | 0.03% | Shares |
| Private Advisor Group, LLC | $209,002 | 26,092 | 0.03% | Shares |
| Belpointe Asset Management LLC | $206,306 | 25,756 | 0.03% | Shares |
| HighTower Advisors, LLC | $205,769 | 25,689 | 0.03% | Shares |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $200,250 | 25,000 | 0.03% | Shares |
| Squarepoint Ops LLC | $199,481 | 24,904 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $197,438 | 24,649 | 0.03% | Shares |
| Creative Planning | $194,811 | 24,321 | 0.03% | Shares |
| Magnetar Financial LLC | $182,660 | 22,804 | 0.02% | Shares |
| JANUS HENDERSON GROUP PLC | $173,556 | 21,600 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $165,006 | 20,600 | 0.02% | Call option |
| Schonfeld Strategic Advisors LLC | $164,572 | 20,546 | 0.02% | Shares |
| GUGGENHEIM CAPITAL LLC | $161,474 | 20,159 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $155,386 | 19,399 | 0.02% | Shares |
| SHERBROOKE PARK ADVISERS LLC | $153,069 | 13,139 | 0.02% | Shares |
| Mariner, LLC | $150,359 | 18,771 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $144,156 | 17,997 | 0.02% | Shares |
| Quarry LP | $141,969 | 17,724 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $141,833 | 17,707 | 0.02% | Shares |
| Russell Investments Group, Ltd. | $139,285 | 17,389 | 0.02% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $138,717 | 17,318 | 0.02% | Shares |
| Tannin Capital LLC | $131,684 | 16,440 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $126,590 | 15,804 | 0.02% | Shares |
| State of New Jersey Common Pension Fund D | $122,161 | 15,251 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $119,349 | 14,900 | 0.02% | Put option |
| INTECH INVESTMENT MANAGEMENT LLC | $118,812 | 14,833 | 0.02% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $111,267 | 13,891 | 0.01% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $104,250 | 13,015 | 0.01% | Shares |
| nVerses Capital, LLC | $102,888 | 12,845 | 0.01% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $98,659 | 12,317 | 0.01% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $94,282 | 11,040 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $92,916 | 11,600 | 0.01% | Shares |
| AMERICAN CENTURY COMPANIES INC | $92,099 | 11,498 | 0.01% | Shares |
| ProShare Advisors LLC | $90,713 | 11,325 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $84,906 | 10,600 | 0.01% | Shares |
| Abel Hall, LLC | $84,393 | 10,536 | 0.01% | Shares |
| Pictet Asset Management Holding SA | $83,000 | 10,362 | 0.01% | Shares |
| Allianz Asset Management GmbH | $81,702 | 10,200 | 0.01% | Shares |
| PRUDENTIAL FINANCIAL INC | $80,460 | 10,045 | 0.01% | Shares |
| SYON CAPITAL LLC | $80,420 | 10,040 | 0.01% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $66,643 | 8,320 | 0.01% | Shares |
| Rockefeller Capital Management L.P. | $43,687 | 5,454 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $39,153 | 4,888 | 0.01% | Shares |
| DIADEMA PARTNERS LP | $38,929 | 4,860 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $35,572 | 4,441 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $33,786 | 4,218 | 0.00% | Shares |
| Arax Advisory Partners | $33,394 | 4,169 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $31,000 | 3,874 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $27,562 | 3,441 | 0.00% | Shares |
| SIGNATUREFD, LLC | $25,728 | 3,212 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $24,005 | 2,997 | 0.00% | Shares |
| OSTERWEIS CAPITAL MANAGEMENT INC | $21,122 | 2,637 | 0.00% | Shares |
| Bernard Wealth Management Corp. | $19,385 | 2,420 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $17,131 | 2,160 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $16,941 | 2,115 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $16,773 | 2,094 | 0.00% | Shares |
| Smartleaf Asset Management LLC | $16,709 | 1,952 | 0.00% | Shares |
| Janney Montgomery Scott LLC | $16,537 | 2,064,498 | 0.00% | Shares |
| CAZ INVESTMENTS LP | $16,020 | 2,000 | 0.00% | Shares |
| US BANCORP \DE\ | $12,808 | 1,599 | 0.00% | Shares |
| GAMMA Investing LLC | $10,061 | 1,256 | 0.00% | Shares |
| Persistent Asset Partners Ltd | $9,940 | 1,241 | 0.00% | Shares |
| Lindbrook Capital, LLC | $9,536 | 758 | 0.00% | Shares |
| Versant Capital Management, Inc | $9,085 | 2,108 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $8,138 | 1,016 | 0.00% | Shares |
| Heritage Wealth Advisors | $8,010 | 1,000 | 0.00% | Shares |
| Global Retirement Partners, LLC | $7,930 | 990 | 0.00% | Shares |
| Ameritas Advisory Services, LLC | $7,097 | 886 | 0.00% | Shares |
| CWM, LLC | $6,697 | 834 | 0.00% | Shares |
| Allworth Financial LP | $6,609 | 825 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $4,470 | 558 | 0.00% | Shares |
| BROWN, LISLE/CUMMINGS, INC. | $3,204 | 400 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $2,997 | 374 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $2,964 | 370 | 0.00% | Shares |
| Hilton Head Capital Partners, LLC | $2,924 | 365 | 0.00% | Shares |
| COMERICA BANK | $2,528 | 217 | 0.00% | Shares |
| Sterling Capital Management LLC | $1,730 | 216 | 0.00% | Shares |
| HighMark Wealth Management LLC | $1,602 | 200 | 0.00% | Shares |
| Tidemark, LLC | $1,354 | 169 | 0.00% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1,177 | 147 | 0.00% | Shares |
| Optiver Holding B.V. | $1,121 | 140 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $1,001 | 125 | 0.00% | Shares |
| Larson Financial Group LLC | $873 | 109 | 0.00% | Shares |
| SIT INVESTMENT ASSOCIATES INC | $744 | 92,875 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $737 | 92 | 0.00% | Shares |
| Cambridge Investment Research Advisors, Inc. | $698 | 87,161 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $641 | 80 | 0.00% | Shares |
| JPL Wealth Management, LLC | $441 | 55 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $406 | 50,579 | 0.00% | Shares |
| Essential Partners LLC | $264 | 33 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $256 | 32 | 0.00% | Shares |
| Strategic Wealth Partners, Ltd. | $160 | 20 | 0.00% | Shares |
| SG Americas Securities, LLC | $140 | 17,534 | 0.00% | Shares |
| FOSTER & MOTLEY INC | $118 | 14,780 | 0.00% | Shares |
| AMICA MUTUAL INSURANCE CO | $115 | 14,350 | 0.00% | Shares |
| Virtu Financial LLC | $88 | 10,938 | 0.00% | Shares |
| IFP Advisors, Inc | $88 | 11 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $72 | 9 | 0.00% | Shares |
| BESSEMER GROUP INC | $60 | 7,525 | 0.00% | Shares |
| Clearstead Advisors, LLC | $42 | 5 | 0.00% | Shares |
| Keating Financial Advisory Services, Inc. | $40 | 5 | 0.00% | Shares |
| GHP Investment Advisors, Inc. | $25 | 3 | 0.00% | Shares |
| Wealth Enhancement Trust Services, Inc. | $16 | 2 | 0.00% | Shares |
| CX Institutional | $12 | 2,890 | 0.00% | Shares |
| Capital Analysts, LLC | $10 | 1,300 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $9 | 1 | 0.00% | Shares |
| Pacer Advisors, Inc. | $9 | 1,062 | 0.00% | Shares |
| Hughes Financial Services, LLC | $8 | 1 | 0.00% | Shares |
| LANARK FINANCIAL, INC. | $8 | 1 | 0.00% | Shares |
| Avion Wealth | $4 | 500 | 0.00% | Shares |
| Amica Retiree Medical Trust | $3 | 346 | 0.00% | Shares |
| Covestor Ltd | $0 | 46 | 0.00% | Shares |