SVRA — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| NEA Management Company, LLC | $150,742,986 | 24,471,264 | 10.78% | Shares |
| Bain Capital Life Sciences Investors, LLC | $108,419,826 | 17,600,621 | 7.75% | Shares |
| Venrock Adviser, LLC | $90,835,009 | 14,745,943 | 6.50% | Shares |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $83,585,040 | 13,569,000 | 5.98% | Shares |
| BlackRock, Inc. | $76,966,107 | 12,494,498 | 5.50% | Shares |
| TCG Crossover Management, LLC | $76,151,183 | 12,362,205 | 5.45% | Shares |
| VANGUARD GROUP INC | $60,551,132 | 10,041,647 | 4.33% | Shares |
| Frazier Life Sciences Management, L.P. | $59,880,448 | 9,720,852 | 4.28% | Shares |
| Polar Capital Holdings Plc | $58,777,402 | 9,541,786 | 4.20% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $48,864,477 | 7,932,545 | 3.49% | Shares |
| Nantahala Capital Management, LLC | $42,977,150 | 6,976,810 | 3.07% | Shares |
| STATE STREET CORP | $40,368,624 | 6,553,348 | 2.89% | Shares |
| MARSHALL WACE, LLP | $38,543,053 | 6,256,989 | 2.76% | Shares |
| RTW INVESTMENTS, LP | $36,666,661 | 5,952,380 | 2.62% | Shares |
| Woodline Partners LP | $26,149,933 | 4,245,119 | 1.87% | Shares |
| ORBIMED ADVISORS LLC | $24,392,984 | 3,959,900 | 1.74% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $23,857,705 | 3,872,133 | 1.71% | Shares |
| Spruce Street Capital LP | $21,267,868 | 3,452,576 | 1.52% | Shares |
| Rosalind Advisors, Inc. | $19,577,225 | 3,178,121 | 1.40% | Shares |
| EMERALD ADVISERS, LLC | $19,394,384 | 3,148,439 | 1.39% | Shares |
| Pictet Asset Management Holding SA | $17,020,419 | 2,763,055 | 1.22% | Shares |
| Vestal Point Capital, LP | $16,755,200 | 2,720,000 | 1.20% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $16,600,042 | 2,694,812 | 1.19% | Shares |
| D. E. Shaw & Co., Inc. | $15,492,388 | 2,514,998 | 1.11% | Shares |
| Affinity Asset Advisors, LLC | $15,474,862 | 2,512,153 | 1.11% | Shares |
| EMERALD MUTUAL FUND ADVISERS TRUST | $14,636,154 | 2,375,999 | 1.05% | Shares |
| NAN FUNG TRINITY (HK) LTD | $11,348,876 | 1,842,350 | 0.81% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $10,076,762 | 1,635,838 | 0.72% | Shares |
| ADAR1 Capital Management, LLC | $8,644,999 | 1,403,409 | 0.62% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8,349,627 | 1,355,459 | 0.60% | Shares |
| ALGERT GLOBAL LLC | $8,188,235 | 1,329,259 | 0.59% | Shares |
| NORTHERN TRUST CORP | $8,025,894 | 1,302,905 | 0.57% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,211,802 | 1,170,747 | 0.52% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,412,597 | 1,041,006 | 0.46% | Shares |
| Longaeva Partners L.P. | $6,257,864 | 1,015,887 | 0.45% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $6,219,696 | 1,009,691 | 0.44% | Shares |
| SUPERSTRING CAPITAL MANAGEMENT LP | $6,021,154 | 977,460 | 0.43% | Shares |
| DEUTSCHE BANK AG\ | $5,328,129 | 864,956 | 0.38% | Shares |
| GOLDMAN SACHS GROUP INC | $5,108,767 | 829,345 | 0.37% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $4,657,970 | 756,164 | 0.33% | Shares |
| Swedbank AB | $4,409,944 | 715,900 | 0.32% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $4,264,020 | 692,211 | 0.30% | Shares |
| F/m Investments LLC | $4,055,461 | 658,354 | 0.29% | Shares |
| Sio Capital Management, LLC | $3,804,878 | 617,675 | 0.27% | Shares |
| AXA Investment Managers S.A. | $3,760,142 | 1,053,261 | 0.27% | Shares |
| KVP Capital Advisors, LP | $3,728,525 | 605,280 | 0.27% | Shares |
| Integral Health Asset Management, LLC | $3,696,000 | 600,000 | 0.26% | Shares |
| BANK OF AMERICA CORP /DE/ | $3,205,393 | 520,356 | 0.23% | Shares |
| UBS Group AG | $3,160,240 | 513,026 | 0.23% | Shares |
| Moody Aldrich Partners LLC | $2,974,005 | 482,793 | 0.21% | Shares |
| Y-Intercept (Hong Kong) Ltd | $2,529,351 | 410,609 | 0.18% | Shares |
| Bank of New York Mellon Corp | $2,293,779 | 372,367 | 0.16% | Shares |
| MORGAN STANLEY | $2,254,351 | 365,966 | 0.16% | Shares |
| Sofinnova Investments, Inc. | $2,246,940 | 364,763 | 0.16% | Shares |
| Nuveen, LLC | $2,090,205 | 339,319 | 0.15% | Shares |
| Seven Fleet Capital Management LP | $1,904,074 | 309,103 | 0.14% | Shares |
| WEDGE CAPITAL MANAGEMENT L L P/NC | $1,681,669 | 307,998 | 0.12% | Shares |
| CITADEL ADVISORS LLC | $1,608,049 | 261,047 | 0.11% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $1,533,156 | 248,889 | 0.11% | Shares |
| Walleye Capital LLC | $1,532,115 | 248,720 | 0.11% | Shares |
| HighVista Strategies LLC | $1,493,054 | 242,379 | 0.11% | Shares |
| Eversept Partners, LP | $1,259,276 | 204,428 | 0.09% | Shares |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1,236,693 | 205,090 | 0.09% | Shares |
| Invesco Ltd. | $1,236,220 | 200,685 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $1,146,187 | 186,071 | 0.08% | Shares |
| Swiss National Bank | $1,139,600 | 185,000 | 0.08% | Shares |
| WELLS FARGO & COMPANY/MN | $1,106,108 | 179,563 | 0.08% | Shares |
| FMR LLC | $1,076,387 | 174,738 | 0.08% | Shares |
| CITIGROUP INC | $984,886 | 159,884 | 0.07% | Shares |
| Jain Global LLC | $879,605 | 142,793 | 0.06% | Shares |
| XTX Topco Ltd | $754,662 | 122,510 | 0.05% | Shares |
| GLENMEDE TRUST CO NA | $707,432 | 114,843 | 0.05% | Shares |
| ALLIANCEBERNSTEIN L.P. | $693,638 | 127,040 | 0.05% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $621,766 | 100,936 | 0.04% | Shares |
| DCF Advisers, LLC | $616,000 | 100,000 | 0.04% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $585,921 | 95,117 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $574,728 | 93,300 | 0.04% | Call option |
| Russell Investments Group, Ltd. | $556,309 | 90,310 | 0.04% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $554,400 | 90,000 | 0.04% | Shares |
| MetLife Investment Management, LLC | $549,817 | 89,256 | 0.04% | Shares |
| Rafferty Asset Management, LLC | $547,279 | 88,844 | 0.04% | Shares |
| ENVESTNET ASSET MANAGEMENT INC | $531,534 | 86,288 | 0.04% | Shares |
| JPMORGAN CHASE & CO | $518,032 | 85,909 | 0.04% | Shares |
| OPTIMIZE FINANCIAL INC. | $516,276 | 83,811 | 0.04% | Shares |
| Cresset Asset Management, LLC | $513,337 | 83,334 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $494,360 | 80,471 | 0.04% | Shares |
| Birchview Capital, LP | $492,800 | 80,000 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $473,291 | 76,833 | 0.03% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $461,236 | 74,876 | 0.03% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $430,492 | 69,885 | 0.03% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $405,427 | 65,816 | 0.03% | Shares |
| Susquehanna Portfolio Strategies, LLC | $388,560 | 63,078 | 0.03% | Shares |
| Virtus Investment Advisers, LLC | $383,183 | 62,205 | 0.03% | Shares |
| Verdad Advisers, LP | $380,435 | 61,759 | 0.03% | Shares |
| Creative Planning | $378,951 | 61,518 | 0.03% | Shares |
| Legal & General Group Plc | $350,819 | 56,951 | 0.03% | Shares |
| FIFTH THIRD BANCORP | $333,595 | 54,155 | 0.02% | Shares |
| Avidity Partners Management LP | $308,000 | 50,000 | 0.02% | Shares |
| Sivia Capital Partners, LLC | $298,760 | 48,500 | 0.02% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $293,450 | 47,638 | 0.02% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $287,841 | 52,718 | 0.02% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $285,824 | 46,400 | 0.02% | Put option |
| PROFUND ADVISORS LLC | $285,645 | 46,371 | 0.02% | Shares |
| DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. | $283,360 | 46,000 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $280,003 | 45,455 | 0.02% | Shares |
| Jump Financial, LLC | $273,504 | 44,400 | 0.02% | Shares |
| SEI INVESTMENTS CO | $267,523 | 43,429 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $256,872 | 41,700 | 0.02% | Put option |
| Police & Firemen's Retirement System of New Jersey | $250,324 | 40,637 | 0.02% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $247,891 | 40,242 | 0.02% | Shares |
| JANUS HENDERSON GROUP PLC | $247,018 | 45,200 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $244,552 | 39,700 | 0.02% | Call option |
| TWO SIGMA INVESTMENTS, LP | $231,906 | 37,647 | 0.02% | Shares |
| BARCLAYS PLC | $230,076 | 37,350 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $217,448 | 35,300 | 0.02% | Call option |
| Squarepoint Ops LLC | $205,054 | 33,288 | 0.01% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $201,678 | 32,740 | 0.01% | Shares |
| China Universal Asset Management Co., Ltd. | $200,902 | 32,614 | 0.01% | Shares |
| STRS OHIO | $199,584 | 32,400 | 0.01% | Shares |
| Graham Capital Management, L.P. | $197,434 | 32,051 | 0.01% | Shares |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $193,714 | 31,447 | 0.01% | Shares |
| Skopos Labs, Inc. | $183,828 | 33,668 | 0.01% | Shares |
| State of New Jersey Common Pension Fund D | $183,673 | 29,817 | 0.01% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $176,835 | 28,707 | 0.01% | Shares |
| Farther Finance Advisors, LLC | $166,665 | 27,056 | 0.01% | Shares |
| ProShare Advisors LLC | $164,798 | 26,753 | 0.01% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $162,784 | 26,426 | 0.01% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $156,741 | 25,445 | 0.01% | Shares |
| WINTON GROUP Ltd | $151,290 | 24,560 | 0.01% | Shares |
| PRUDENTIAL FINANCIAL INC | $151,259 | 24,555 | 0.01% | Shares |
| Orion Porfolio Solutions, LLC | $150,698 | 24,464 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $144,514 | 23,460 | 0.01% | Shares |
| Trexquant Investment LP | $133,980 | 21,750 | 0.01% | Shares |
| Quantinno Capital Management LP | $133,241 | 21,630 | 0.01% | Shares |
| BANK OF MONTREAL /CAN/ | $128,584 | 20,874 | 0.01% | Shares |
| BROWN ADVISORY INC | $128,461 | 20,854 | 0.01% | Shares |
| OPPENHEIMER & CO INC | $104,720 | 17,000 | 0.01% | Shares |
| EntryPoint Capital, LLC | $95,813 | 15,554 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $93,632 | 15,200 | 0.01% | Shares |
| OSAIC HOLDINGS, INC. | $90,885 | 14,754 | 0.01% | Shares |
| INCEPTIONR LLC | $90,392 | 14,674 | 0.01% | Shares |
| XPONANCE LLC | $90,145 | 14,634 | 0.01% | Shares |
| US BANCORP \DE\ | $86,825 | 14,095 | 0.01% | Shares |
| Sanctuary Advisors, LLC | $86,579 | 14,055 | 0.01% | Shares |
| Cubist Systematic Strategies, LLC | $85,991 | 24,087 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $85,532 | 13,885 | 0.01% | Shares |
| Magnetar Financial LLC | $84,392 | 13,700 | 0.01% | Shares |
| MML INVESTORS SERVICES, LLC | $81,552 | 13,239 | 0.01% | Shares |
| JANE STREET GROUP, LLC | $80,696 | 13,100 | 0.01% | Put option |
| E Fund Management Co., Ltd. | $77,166 | 12,527 | 0.01% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $75,947 | 12,329 | 0.01% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $73,101 | 11,867 | 0.01% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $72,060 | 11,698 | 0.01% | Shares |
| Sequoia Financial Advisors, LLC | $69,473 | 11,278 | 0.00% | Shares |
| TWO SIGMA ADVISERS, LP | $64,774 | 10,742 | 0.00% | Shares |
| Granite Investment Partners, LLC | $64,606 | 10,488 | 0.00% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $63,565 | 10,319 | 0.00% | Shares |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $62,592 | 10,161 | 0.00% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $60,322 | 16,897 | 0.00% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $56,456 | 9,165 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $52,633 | 14,743 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $40,231 | 6,531 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $35,000 | 5,651 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $26,525 | 4,306 | 0.00% | Shares |
| 1620 INVESTMENT ADVISORS, INC. | $18,480 | 3,000 | 0.00% | Shares |
| COMERICA BANK | $12,693 | 2,105 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $10,842 | 1,760 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $10,091 | 1,638 | 0.00% | Shares |
| Larson Financial Group LLC | $4,873 | 791 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $4,318 | 701 | 0.00% | Shares |
| Sterling Capital Management LLC | $3,308 | 537 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $3,049 | 495 | 0.00% | Shares |
| CWM, LLC | $3,025 | 554 | 0.00% | Shares |
| Optiver Holding B.V. | $2,723 | 442 | 0.00% | Shares |
| GAMMA Investing LLC | $2,519 | 409 | 0.00% | Shares |
| Point72 Europe (London) LLP | $2,203 | 617 | 0.00% | Shares |
| Allworth Financial LP | $1,701 | 276 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $1,386 | 225 | 0.00% | Shares |
| Keating Financial Advisory Services, Inc. | $1,312 | 213 | 0.00% | Shares |
| Quarry LP | $1,109 | 180 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $861 | 146 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $775 | 125,676 | 0.00% | Shares |
| Arax Advisory Partners | $721 | 117 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $616 | 100 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $401 | 65 | 0.00% | Shares |
| SG Americas Securities, LLC | $382 | 61,977 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $289 | 47 | 0.00% | Shares |
| Global Retirement Partners, LLC | $179 | 29 | 0.00% | Shares |
| Sunbelt Securities, Inc. | $136 | 25 | 0.00% | Shares |
| CANADA LIFE ASSURANCE Co | $74 | 11,940 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $37 | 6 | 0.00% | Shares |
| Clearstead Advisors, LLC | $19 | 3 | 0.00% | Shares |
| Pacer Advisors, Inc. | $9 | 1,484 | 0.00% | Shares |
| Covestor Ltd | $0 | 74 | 0.00% | Shares |