URGN — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | $167,215,336 | 4,543,895 | 11.19% | Shares |
| BlackRock, Inc. | $117,813,765 | 3,201,461 | 7.88% | Shares |
| MORGAN STANLEY | $94,810,189 | 2,576,363 | 6.34% | Shares |
| Kynam Capital Management, LP | $89,578,818 | 2,434,207 | 5.99% | Shares |
| Jefferies Financial Group Inc. | $80,947,194 | 2,199,652 | 5.42% | Shares |
| AMERICAN CENTURY COMPANIES INC | $62,034,564 | 1,685,719 | 4.15% | Shares |
| ACORN CAPITAL ADVISORS, LLC | $61,581,856 | 1,673,420 | 4.12% | Shares |
| Point72 Asset Management, L.P. | $56,140,203 | 1,525,549 | 3.76% | Shares |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $55,514,521 | 1,508,547 | 3.71% | Shares |
| Opaleye Management Inc. | $52,991,853 | 1,439,996 | 3.55% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $47,912,827 | 1,301,979 | 3.21% | Shares |
| MENORA MIVTACHIM HOLDINGS LTD. | $42,413,141 | 1,152,531 | 2.84% | Shares |
| D. E. Shaw & Co., Inc. | $42,166,139 | 1,145,819 | 2.82% | Shares |
| STATE STREET CORP | $36,913,013 | 1,003,071 | 2.47% | Shares |
| MPM BIOIMPACT LLC | $34,349,672 | 933,415 | 2.30% | Shares |
| Soleus Capital Management, L.P. | $30,537,008 | 829,810 | 2.04% | Shares |
| GOLDMAN SACHS GROUP INC | $30,169,892 | 819,834 | 2.02% | Shares |
| Migdal Insurance & Financial Holdings Ltd. | $28,369,451 | 770,909 | 1.90% | Shares |
| ORBIMED ADVISORS LLC | $24,883,682 | 676,187 | 1.67% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $22,461,394 | 610,364 | 1.50% | Shares |
| Woodline Partners LP | $18,426,717 | 500,726 | 1.23% | Shares |
| Boxer Capital Management, LLC | $18,400,000 | 500,000 | 1.23% | Shares |
| BANK OF AMERICA CORP /DE/ | $17,505,834 | 475,702 | 1.17% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $16,801,334 | 456,558 | 1.12% | Shares |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $14,244,323 | 387,074 | 0.95% | Shares |
| NORTHERN TRUST CORP | $11,208,175 | 304,570 | 0.75% | Shares |
| RICE HALL JAMES & ASSOCIATES, LLC | $11,063,920 | 300,650 | 0.74% | Shares |
| VANGUARD GROUP INC | $10,298,969 | 439,751 | 0.69% | Shares |
| ADAR1 Capital Management, LLC | $9,288,136 | 252,395 | 0.62% | Shares |
| J. Goldman & Co LP | $7,830,120 | 212,775 | 0.52% | Shares |
| Privium Fund Management B.V. | $7,728,000 | 210,000 | 0.52% | Shares |
| FMR LLC | $7,253,198 | 197,098 | 0.49% | Shares |
| SUPERSTRING CAPITAL MANAGEMENT LP | $7,040,318 | 191,313 | 0.47% | Shares |
| Parkman Healthcare Partners LLC | $6,405,555 | 174,064 | 0.43% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5,531,040 | 150,300 | 0.37% | Call option |
| AQR CAPITAL MANAGEMENT LLC | $5,491,591 | 149,228 | 0.37% | Shares |
| TWO SIGMA INVESTMENTS, LP | $5,481,838 | 148,963 | 0.37% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $4,724,016 | 128,370 | 0.32% | Shares |
| UBS Group AG | $4,469,764 | 121,461 | 0.30% | Shares |
| Elmind Capital, LP | $4,416,000 | 120,000 | 0.30% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $4,245,322 | 115,362 | 0.28% | Shares |
| Bank of New York Mellon Corp | $4,159,416 | 113,028 | 0.28% | Shares |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $4,089,989 | 111,141 | 0.27% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4,084,800 | 111,000 | 0.27% | Put option |
| Aisling Capital Management LP | $3,974,400 | 108,000 | 0.27% | Shares |
| MILLENNIUM MANAGEMENT LLC | $3,926,266 | 106,692 | 0.26% | Shares |
| ARK Investment Management LLC | $3,735,494 | 101,508 | 0.25% | Shares |
| Russell Investments Group, Ltd. | $3,495,260 | 94,979 | 0.23% | Shares |
| Nuveen, LLC | $3,389,354 | 92,102 | 0.23% | Shares |
| OAK RIDGE INVESTMENTS LLC | $3,260,149 | 88,591 | 0.22% | Shares |
| WELLS FARGO & COMPANY/MN | $2,952,612 | 80,234 | 0.20% | Shares |
| Informed Momentum Co LLC | $2,917,173 | 79,271 | 0.20% | Shares |
| Swiss National Bank | $2,863,040 | 77,800 | 0.19% | Shares |
| PANAGORA ASSET MANAGEMENT INC | $2,724,083 | 74,024 | 0.18% | Shares |
| TRUIST FINANCIAL CORP | $2,660,125 | 72,286 | 0.18% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $2,622,368 | 71,260 | 0.18% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $2,587,040 | 70,300 | 0.17% | Shares |
| Ally Bridge Group (NY) LLC | $2,545,934 | 69,183 | 0.17% | Shares |
| RHUMBLINE ADVISERS | $2,021,123 | 54,922 | 0.14% | Shares |
| DEUTSCHE BANK AG\ | $1,897,040 | 51,550 | 0.13% | Shares |
| CITADEL ADVISORS LLC | $1,865,760 | 50,700 | 0.12% | Call option |
| Atom Investors LP | $1,717,235 | 46,664 | 0.11% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1,654,123 | 44,949 | 0.11% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,604,443 | 43,599 | 0.11% | Shares |
| JPMORGAN CHASE & CO | $1,426,352 | 39,544 | 0.10% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,369,218 | 37,207 | 0.09% | Shares |
| Coastal Bridge Advisors, LLC | $1,361,600 | 37,000 | 0.09% | Shares |
| Legal & General Group Plc | $1,318,543 | 35,830 | 0.09% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $1,289,987 | 35,054 | 0.09% | Shares |
| J. Goldman & Co LP | $1,251,200 | 34,000 | 0.08% | Call option |
| Focus Partners Wealth | $1,216,645 | 33,061 | 0.08% | Shares |
| Schonfeld Strategic Advisors LLC | $1,194,491 | 32,459 | 0.08% | Shares |
| ALGERT GLOBAL LLC | $1,190,480 | 32,350 | 0.08% | Shares |
| AMERIPRISE FINANCIAL INC | $1,165,383 | 31,668 | 0.08% | Shares |
| POLEN CAPITAL MANAGEMENT LLC | $1,089,832 | 29,615 | 0.07% | Shares |
| Cetera Investment Advisers | $1,065,434 | 28,952 | 0.07% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $956,947 | 26,004 | 0.06% | Shares |
| Invesco Ltd. | $954,113 | 25,927 | 0.06% | Shares |
| HighVista Strategies LLC | $918,822 | 24,968 | 0.06% | Shares |
| MetLife Investment Management, LLC | $915,032 | 24,865 | 0.06% | Shares |
| Palo Alto Investors LP | $901,600 | 24,500 | 0.06% | Shares |
| JANE STREET GROUP, LLC | $897,920 | 24,400 | 0.06% | Call option |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $852,594 | 47,419 | 0.06% | Shares |
| CITIGROUP INC | $841,653 | 22,871 | 0.06% | Shares |
| ALLIANCEBERNSTEIN L.P. | $785,906 | 43,710 | 0.05% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $761,613 | 20,696 | 0.05% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $718,925 | 19,536 | 0.05% | Shares |
| JANE STREET GROUP, LLC | $717,600 | 19,500 | 0.05% | Put option |
| Susquehanna Portfolio Strategies, LLC | $714,067 | 19,404 | 0.05% | Shares |
| XTX Topco Ltd | $713,405 | 19,386 | 0.05% | Shares |
| FRANKLIN RESOURCES INC | $708,878 | 19,263 | 0.05% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $677,046 | 18,398 | 0.05% | Shares |
| Quantinno Capital Management LP | $671,674 | 18,252 | 0.04% | Shares |
| CAPITAL FUND MANAGEMENT S.A. | $647,128 | 17,585 | 0.04% | Shares |
| GLENMEDE TRUST CO NA | $633,180 | 17,206 | 0.04% | Shares |
| Toroso Investments, LLC | $631,684 | 26,972 | 0.04% | Shares |
| CITADEL ADVISORS LLC | $610,880 | 16,600 | 0.04% | Put option |
| Birchview Capital, LP | $606,722 | 16,487 | 0.04% | Shares |
| Engineers Gate Manager LP | $602,710 | 16,378 | 0.04% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $579,122 | 15,737 | 0.04% | Shares |
| PARTNERS CAPITAL INVESTMENT GROUP, LLP | $566,131 | 15,384 | 0.04% | Shares |
| LPL Financial LLC | $532,018 | 14,457 | 0.04% | Shares |
| Verdad Advisers, LP | $531,392 | 14,440 | 0.04% | Shares |
| MML INVESTORS SERVICES, LLC | $527,160 | 14,325 | 0.04% | Shares |
| MAI Capital Management | $521,198 | 14,163 | 0.03% | Shares |
| CITADEL ADVISORS LLC | $477,848 | 12,985 | 0.03% | Shares |
| DNB Asset Management AS | $474,941 | 12,906 | 0.03% | Shares |
| State of New Jersey Common Pension Fund D | $463,422 | 12,593 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $462,429 | 12,566 | 0.03% | Shares |
| Creative Planning | $444,360 | 12,075 | 0.03% | Shares |
| Integrated Wealth Concepts LLC | $432,069 | 11,741 | 0.03% | Shares |
| Arax Advisory Partners | $431,996 | 11,739 | 0.03% | Shares |
| Squarepoint Ops LLC | $430,523 | 11,699 | 0.03% | Shares |
| WOLVERINE TRADING, LLC | $415,338 | 21,700 | 0.03% | Call option |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $412,050 | 11,197 | 0.03% | Shares |
| ROYAL BANK OF CANADA | $407,000 | 11,060 | 0.03% | Shares |
| Vanguard Investments Australia, Ltd. | $398,176 | 10,820 | 0.03% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $395,453 | 10,746 | 0.03% | Shares |
| KLP KAPITALFORVALTNING AS | $375,360 | 10,200 | 0.03% | Shares |
| BARCLAYS PLC | $374,439 | 10,175 | 0.03% | Shares |
| Allianz Asset Management GmbH | $371,680 | 10,100 | 0.02% | Shares |
| Cresset Asset Management, LLC | $366,749 | 9,966 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $355,488 | 9,660 | 0.02% | Shares |
| JANE STREET GROUP, LLC | $349,784 | 9,505 | 0.02% | Shares |
| Orion Porfolio Solutions, LLC | $345,810 | 9,397 | 0.02% | Shares |
| JANUS HENDERSON GROUP PLC | $343,132 | 19,100 | 0.02% | Shares |
| Vanguard Global Advisers, LLC | $311,770 | 8,472 | 0.02% | Shares |
| Main Street Financial Solutions, LLC | $301,377 | 8,190 | 0.02% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $298,816 | 8,120 | 0.02% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $294,676 | 7,642 | 0.02% | Shares |
| Baader Bank Aktiengesellschaft | $294,400 | 8,000 | 0.02% | Shares |
| FOX RUN MANAGEMENT, L.L.C. | $292,818 | 7,957 | 0.02% | Shares |
| China Universal Asset Management Co., Ltd. | $285,347 | 7,754 | 0.02% | Shares |
| DEBUSSY CAPITAL MANAGEMENT LP | $281,585 | 15,661 | 0.02% | Shares |
| Mariner, LLC | $280,527 | 7,623 | 0.02% | Shares |
| HAP Trading, LLC | $271,342 | 19,806 | 0.02% | Shares |
| Kathmere Capital Management, LLC | $270,848 | 7,360 | 0.02% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $265,402 | 7,212 | 0.02% | Shares |
| ProShare Advisors LLC | $264,187 | 7,179 | 0.02% | Shares |
| DIADEMA PARTNERS LP | $262,642 | 7,137 | 0.02% | Shares |
| Pictet Asset Management Holding SA | $257,600 | 7,000 | 0.02% | Shares |
| PRUDENTIAL FINANCIAL INC | $256,680 | 6,975 | 0.02% | Shares |
| Jain Global LLC | $253,994 | 6,902 | 0.02% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $249,578 | 6,782 | 0.02% | Shares |
| Brookstone Capital Management | $220,800 | 6,000 | 0.01% | Shares |
| RITHOLTZ WEALTH MANAGEMENT | $201,002 | 5,462 | 0.01% | Shares |
| Nebula Research & Development LLC | $162,249 | 11,843 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $142,306 | 3,867 | 0.01% | Shares |
| GROUP ONE TRADING LLC | $112,093 | 3,046 | 0.01% | Shares |
| OSAIC HOLDINGS, INC. | $83,535 | 2,270 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $82,837 | 2,251 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $80,187 | 2,179 | 0.01% | Shares |
| Quantbot Technologies LP | $78,494 | 2,133 | 0.01% | Shares |
| SG Americas Securities, LLC | $75,547 | 2,052,906 | 0.01% | Shares |
| CWM, LLC | $70,014 | 3,894 | 0.00% | Shares |
| Persistent Asset Partners Ltd | $65,872 | 1,790 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $40,664 | 1,105 | 0.00% | Shares |
| Activest Wealth Management | $36,837 | 1,001 | 0.00% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $36,542 | 993 | 0.00% | Shares |
| FEDERATED HERMES, INC. | $35,254 | 958 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $34,540 | 1,000 | 0.00% | Shares |
| Rossby Financial, LCC | $28,336 | 770 | 0.00% | Shares |
| Pinnacle Wealth Planning Services, Inc. | $25,318 | 688 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $21,896 | 595 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $21,492 | 584 | 0.00% | Shares |
| State of Wyoming | $19,504 | 530 | 0.00% | Shares |
| Larson Financial Group LLC | $17,848 | 485 | 0.00% | Shares |
| GAMMA Investing LLC | $16,229 | 441 | 0.00% | Shares |
| Napier Financial, LLC | $14,720 | 400 | 0.00% | Shares |
| NFSG Corp | $12,880 | 350 | 0.00% | Shares |
| CIBC Private Wealth Group LLC | $10,155 | 509 | 0.00% | Shares |
| Sterling Capital Management LLC | $9,090 | 247 | 0.00% | Shares |
| Allworth Financial LP | $8,869 | 241 | 0.00% | Shares |
| Costello Asset Management, INC | $7,360 | 200 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $4,122 | 112 | 0.00% | Shares |
| NewEdge Advisors, LLC | $3,680 | 100 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $3,091 | 84 | 0.00% | Shares |
| US BANCORP \DE\ | $2,981 | 81 | 0.00% | Shares |
| Optiver Holding B.V. | $2,650 | 72 | 0.00% | Shares |
| Smartleaf Asset Management LLC | $2,597 | 72 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $2,502 | 68 | 0.00% | Shares |
| Essential Partners LLC | $1,766 | 48 | 0.00% | Shares |
| Annandale Capital, LLC | $1,672 | 45,425 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $1,660 | 45 | 0.00% | Shares |
| Altshuler Shaham Ltd | $1,435 | 39 | 0.00% | Shares |
| Quarry LP | $1,325 | 36 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $1,289 | 35,003 | 0.00% | Shares |
| IFP Advisors, Inc | $1,141 | 31 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $883 | 24 | 0.00% | Shares |
| DecisionPoint Financial, LLC | $835 | 22 | 0.00% | Shares |
| SIGNATUREFD, LLC | $589 | 16 | 0.00% | Shares |
| True Wealth Design, LLC | $589 | 16 | 0.00% | Shares |
| Jackson Creek Investment Advisors LLC | $540 | 14,134 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $405 | 11 | 0.00% | Shares |
| SHIKIAR ASSET MANAGEMENT INC | $322 | 8,750 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $297 | 8,113 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $221 | 6 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $147 | 4 | 0.00% | Shares |
| Hughes Financial Services, LLC | $110 | 3 | 0.00% | Shares |
| Keating Financial Advisory Services, Inc. | $74 | 2 | 0.00% | Shares |
| KBC Group NV | $49 | 1,340 | 0.00% | Shares |
| Clearstead Advisors, LLC | $37 | 1 | 0.00% | Shares |
| Covestor Ltd | $1 | 14 | 0.00% | Shares |