VRDN — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $305,029,074 | 16,604,740 | 11.87% | Shares |
| VANGUARD GROUP INC | $174,649,921 | 5,612,144 | 6.79% | Shares |
| BlackRock, Inc. | $157,090,835 | 8,551,488 | 6.11% | Shares |
| Bellevue Group AG | $123,665,169 | 6,731,909 | 4.81% | Shares |
| Paradigm Biocapital Advisors LP | $123,515,986 | 6,723,788 | 4.81% | Shares |
| Kynam Capital Management, LP | $118,557,720 | 6,453,877 | 4.61% | Shares |
| STATE STREET CORP | $112,515,809 | 6,124,976 | 4.38% | Shares |
| Fairmount Funds Management LLC | $93,520,347 | 5,090,928 | 3.64% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $84,076,918 | 4,576,860 | 3.27% | Shares |
| Deep Track Capital, LP | $65,998,634 | 3,592,740 | 2.57% | Shares |
| Venrock Adviser, LLC | $59,847,935 | 3,257,917 | 2.33% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $57,468,009 | 3,128,362 | 2.24% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $50,569,432 | 2,752,827 | 1.97% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $45,968,039 | 2,501,869 | 1.79% | Shares |
| Avoro Capital Advisors LLC | $45,925,000 | 2,500,000 | 1.79% | Shares |
| BAKER BROS. ADVISORS LP | $43,776,169 | 2,383,025 | 1.70% | Shares |
| Point72 Asset Management, L.P. | $43,044,731 | 2,343,208 | 1.67% | Shares |
| Caligan Partners LP | $40,303,431 | 2,193,981 | 1.57% | Shares |
| NOVO HOLDINGS A/S | $39,219,950 | 2,135,000 | 1.53% | Shares |
| TANG CAPITAL MANAGEMENT LLC | $32,930,540 | 1,792,626 | 1.28% | Shares |
| Fisher Asset Management, LLC | $32,163,113 | 1,750,850 | 1.25% | Shares |
| Candriam S.C.A. | $31,340,230 | 1,707,698 | 1.22% | Shares |
| GOLDMAN SACHS GROUP INC | $31,069,254 | 1,691,304 | 1.21% | Shares |
| First Turn Management, LLC | $30,677,900 | 1,670,000 | 1.19% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $29,607,274 | 1,611,521 | 1.15% | Shares |
| ALLIANCEBERNSTEIN L.P. | $27,220,459 | 1,391,639 | 1.06% | Shares |
| UBS Group AG | $26,247,845 | 1,428,843 | 1.02% | Shares |
| Parkman Healthcare Partners LLC | $25,306,071 | 1,377,576 | 0.98% | Shares |
| Balyasny Asset Management L.P. | $23,511,010 | 1,279,859 | 0.91% | Shares |
| D. E. Shaw & Co., Inc. | $21,717,418 | 1,182,222 | 0.84% | Shares |
| RICE HALL JAMES & ASSOCIATES, LLC | $21,601,393 | 1,175,906 | 0.84% | Shares |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $20,435,027 | 1,112,413 | 0.79% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $18,592,975 | 1,012,138 | 0.72% | Shares |
| Elmind Capital, LP | $18,093,182 | 984,931 | 0.70% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $17,375,111 | 888,298 | 0.68% | Shares |
| BANK OF AMERICA CORP /DE/ | $17,347,618 | 944,345 | 0.67% | Shares |
| NORTHERN TRUST CORP | $15,862,330 | 863,491 | 0.62% | Shares |
| Eversept Partners, LP | $15,268,079 | 831,142 | 0.59% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14,972,046 | 815,027 | 0.58% | Shares |
| Schonfeld Strategic Advisors LLC | $14,576,741 | 793,508 | 0.57% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $14,119,182 | 768,600 | 0.55% | Shares |
| MORGAN STANLEY | $13,388,384 | 728,817 | 0.52% | Shares |
| Woodline Partners LP | $12,876,066 | 700,929 | 0.50% | Shares |
| JPMORGAN CHASE & CO | $12,106,209 | 639,929 | 0.47% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $12,079,892 | 657,588 | 0.47% | Shares |
| PERCEPTIVE ADVISORS LLC | $10,690,973 | 581,980 | 0.42% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $9,939,235 | 541,058 | 0.39% | Shares |
| EMERALD ADVISERS, LLC | $9,870,715 | 537,328 | 0.38% | Shares |
| DEUTSCHE BANK AG\ | $8,870,414 | 482,875 | 0.35% | Shares |
| ALGERT GLOBAL LLC | $8,858,694 | 482,237 | 0.34% | Shares |
| Ikarian Capital, LLC | $7,807,251 | 425,000 | 0.30% | Shares |
| Yiheng Capital Management, L.P. | $7,356,524 | 400,464 | 0.29% | Shares |
| Jump Financial, LLC | $7,315,871 | 398,251 | 0.28% | Shares |
| EMERALD MUTUAL FUND ADVISERS TRUST | $7,266,180 | 395,546 | 0.28% | Shares |
| PANAGORA ASSET MANAGEMENT INC | $5,963,967 | 324,658 | 0.23% | Shares |
| XTX Topco Ltd | $5,054,781 | 275,165 | 0.20% | Shares |
| Bank of New York Mellon Corp | $4,924,265 | 268,060 | 0.19% | Shares |
| Blue Owl Capital Holdings LP | $4,776,200 | 260,000 | 0.19% | Shares |
| Affinity Asset Advisors, LLC | $4,592,500 | 250,000 | 0.18% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $4,588,146 | 249,763 | 0.18% | Shares |
| TD Asset Management Inc | $4,328,082 | 235,606 | 0.17% | Shares |
| Nuveen, LLC | $3,659,856 | 199,230 | 0.14% | Shares |
| CAPITAL FUND MANAGEMENT S.A. | $3,634,467 | 197,848 | 0.14% | Shares |
| FIRST TRUST ADVISORS LP | $3,329,268 | 181,234 | 0.13% | Shares |
| Knott David M Jr | $3,324,970 | 181,000 | 0.13% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3,312,993 | 180,348 | 0.13% | Shares |
| Squarepoint Ops LLC | $3,250,663 | 176,955 | 0.13% | Shares |
| Privium Fund Management B.V. | $3,187,489 | 173,516 | 0.12% | Shares |
| HighVista Strategies LLC | $2,937,087 | 159,885 | 0.11% | Shares |
| Swiss National Bank | $2,849,187 | 155,100 | 0.11% | Shares |
| CITIGROUP INC | $2,579,424 | 140,415 | 0.10% | Shares |
| CITADEL ADVISORS LLC | $2,555,267 | 139,100 | 0.10% | Call option |
| F/m Investments LLC | $2,475,560 | 134,761 | 0.10% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2,469,939 | 134,455 | 0.10% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,393,317 | 130,284 | 0.09% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $2,338,520 | 127,301 | 0.09% | Shares |
| KVP Capital Advisors, LP | $2,296,250 | 125,000 | 0.09% | Shares |
| Lighthouse Investment Partners, LLC | $2,204,400 | 120,000 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $2,162,997 | 117,747 | 0.08% | Shares |
| WELLS FARGO & COMPANY/MN | $2,122,893 | 115,563 | 0.08% | Shares |
| Russell Investments Group, Ltd. | $2,117,986 | 115,296 | 0.08% | Shares |
| ALPS ADVISORS INC | $2,049,578 | 111,572 | 0.08% | Shares |
| Rafferty Asset Management, LLC | $1,997,719 | 108,749 | 0.08% | Shares |
| J. Safra Sarasin Holding AG | $1,981,002 | 107,839 | 0.08% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1,862,975 | 101,414 | 0.07% | Shares |
| Invesco Ltd. | $1,853,441 | 100,895 | 0.07% | Shares |
| NOMURA HOLDINGS INC | $1,840,674 | 100,200 | 0.07% | Call option |
| DIADEMA PARTNERS LP | $1,837,000 | 100,000 | 0.07% | Shares |
| Voleon Capital Management LP | $1,792,875 | 97,598 | 0.07% | Shares |
| Y-Intercept (Hong Kong) Ltd | $1,777,408 | 96,756 | 0.07% | Shares |
| Merck & Co., Inc. | $1,716,015 | 93,414 | 0.07% | Shares |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1,692,765 | 92,148 | 0.07% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1,679,055 | 91,402 | 0.07% | Shares |
| Caption Management, LLC | $1,580,555 | 86,040 | 0.06% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $1,499,525 | 81,629 | 0.06% | Shares |
| BARCLAYS PLC | $1,495,851 | 81,429 | 0.06% | Shares |
| Aquatic Capital Management LLC | $1,466,753 | 79,845 | 0.06% | Shares |
| Knights of Columbus Asset Advisors LLC | $1,296,059 | 70,553 | 0.05% | Shares |
| J. Goldman & Co LP | $1,239,975 | 67,500 | 0.05% | Call option |
| Burkehill Global Management, LP | $1,194,050 | 65,000 | 0.05% | Shares |
| Legal & General Group Plc | $1,190,155 | 64,788 | 0.05% | Shares |
| TUDOR INVESTMENT CORP ET AL | $1,142,320 | 62,184 | 0.04% | Shares |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1,117,740 | 60,846 | 0.04% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $1,008,789 | 54,915 | 0.04% | Shares |
| PROFUND ADVISORS LLC | $1,006,180 | 54,773 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $998,223 | 54,051 | 0.04% | Shares |
| MetLife Investment Management, LLC | $968,264 | 52,709 | 0.04% | Shares |
| Greenland Capital Management LP | $918,500 | 50,000 | 0.04% | Shares |
| SEVEN GRAND MANAGERS, LLC | $918,500 | 50,000 | 0.04% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $912,401 | 49,668 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $911,152 | 49,600 | 0.04% | Put option |
| Advisory Services Network, LLC | $879,188 | 47,860 | 0.03% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $856,042 | 46,600 | 0.03% | Call option |
| Headlands Technologies LLC | $855,013 | 46,544 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $840,611 | 45,760 | 0.03% | Shares |
| Quadrature Capital Ltd | $828,083 | 45,078 | 0.03% | Shares |
| CITADEL ADVISORS LLC | $758,736 | 41,303 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $748,578 | 40,750 | 0.03% | Shares |
| Verdad Advisers, LP | $711,323 | 38,722 | 0.03% | Shares |
| DCF Advisers, LLC | $698,060 | 38,000 | 0.03% | Shares |
| DNB Asset Management AS | $657,187 | 35,775 | 0.03% | Shares |
| TWINBEECH CAPITAL LP | $646,624 | 35,200 | 0.03% | Shares |
| AlphaQuest LLC | $617,639 | 19,847 | 0.02% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $582,678 | 31,719 | 0.02% | Shares |
| CITADEL ADVISORS LLC | $573,144 | 31,200 | 0.02% | Put option |
| JANE STREET GROUP, LLC | $551,100 | 30,000 | 0.02% | Call option |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $540,000 | 29,370 | 0.02% | Shares |
| AMERIPRISE FINANCIAL INC | $537,928 | 29,283 | 0.02% | Shares |
| JANUS HENDERSON GROUP PLC | $536,666 | 27,472 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $521,947 | 28,413 | 0.02% | Shares |
| Police & Firemen's Retirement System of New Jersey | $489,395 | 26,641 | 0.02% | Shares |
| Persistent Asset Partners Ltd | $468,251 | 25,490 | 0.02% | Shares |
| Greenland Capital Management LP | $459,250 | 25,000 | 0.02% | Call option |
| State of New Jersey Common Pension Fund D | $459,177 | 24,996 | 0.02% | Shares |
| SBI Okasan Asset Management Co.Ltd. | $417,138 | 22,200 | 0.02% | Shares |
| Quantinno Capital Management LP | $403,203 | 21,949 | 0.02% | Shares |
| 71 West Capital Partners | $393,118 | 21,400 | 0.02% | Shares |
| ARIZONA STATE RETIREMENT SYSTEM | $391,832 | 21,330 | 0.02% | Shares |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $387,056 | 21,070 | 0.02% | Shares |
| Virtus Investment Advisers, LLC | $367,620 | 20,012 | 0.01% | Shares |
| Bayforest Capital Ltd | $363,267 | 19,775 | 0.01% | Shares |
| Brevan Howard Capital Management LP | $358,233 | 19,501 | 0.01% | Shares |
| Creative Planning | $332,644 | 18,108 | 0.01% | Shares |
| KLP KAPITALFORVALTNING AS | $321,475 | 17,500 | 0.01% | Shares |
| Vanguard Investments Australia, Ltd. | $297,043 | 16,170 | 0.01% | Shares |
| E Fund Management Co., Ltd. | $281,686 | 15,334 | 0.01% | Shares |
| Graham Capital Management, L.P. | $281,502 | 15,324 | 0.01% | Shares |
| ALLSTATE CORP | $274,723 | 14,955 | 0.01% | Shares |
| PRUDENTIAL FINANCIAL INC | $271,325 | 14,770 | 0.01% | Shares |
| SEI INVESTMENTS CO | $266,980 | 14,535 | 0.01% | Shares |
| FEDERATED HERMES, INC. | $261,552 | 14,238 | 0.01% | Shares |
| Point72 Asset Management, L.P. | $238,810 | 13,000 | 0.01% | Call option |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $221,910 | 12,080 | 0.01% | Shares |
| ProShare Advisors LLC | $217,226 | 11,825 | 0.01% | Shares |
| Glenmede Investment Management, LP | $214,505 | 9,940 | 0.01% | Shares |
| Corton Capital Inc. | $212,865 | 9,864 | 0.01% | Shares |
| NATIONS FINANCIAL GROUP INC, /IA/ /ADV | $207,067 | 11,272 | 0.01% | Shares |
| Pictet Asset Management Holding SA | $206,203 | 11,225 | 0.01% | Shares |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $203,907 | 11,100 | 0.01% | Shares |
| Man Group plc | $197,294 | 10,740 | 0.01% | Shares |
| Ensign Peak Advisors, Inc | $185,537 | 10,100 | 0.01% | Shares |
| OpenArc Corporate Advisory, LLC | $184,398 | 10,038 | 0.01% | Shares |
| Greenland Capital Management LP | $183,700 | 10,000 | 0.01% | Put option |
| Velan Capital Investment Management LP | $183,700 | 10,000 | 0.01% | Shares |
| LMR Partners LLP | $183,700 | 10,000 | 0.01% | Shares |
| Caitong International Asset Management Co., Ltd | $159,360 | 8,675 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $150,597 | 8,198 | 0.01% | Shares |
| Larson Financial Group LLC | $142,955 | 7,782 | 0.01% | Shares |
| Eleva Capital SAS | $139,385 | 7,126 | 0.01% | Shares |
| Ghisallo Capital Management LLC | $128,590 | 7,000 | 0.01% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $105,599 | 5,748,410 | 0.00% | Shares |
| LAZARD ASSET MANAGEMENT LLC | $98,941 | 5,386 | 0.00% | Shares |
| Clearstead Advisors, LLC | $92,384 | 5,029 | 0.00% | Shares |
| STRS OHIO | $82,665 | 4,500 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $61,317 | 3,338 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $60,713 | 3,305 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $53,000 | 2,909 | 0.00% | Shares |
| State of Wyoming | $42,747 | 2,327 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $31,192 | 1,698 | 0.00% | Shares |
| Sterling Capital Management LLC | $30,531 | 1,662 | 0.00% | Shares |
| Federation des caisses Desjardins du Quebec | $30,035 | 1,635 | 0.00% | Shares |
| Kemnay Advisory Services Inc. | $17,543 | 955 | 0.00% | Shares |
| J.Safra Asset Management Corp | $17,488 | 952 | 0.00% | Shares |
| Allworth Financial LP | $11,482 | 625 | 0.00% | Shares |
| CWM, LLC | $10,523 | 538 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $10,416 | 567 | 0.00% | Shares |
| Optiver Holding B.V. | $9,957 | 542 | 0.00% | Shares |
| COMERICA BANK | $9,542 | 307 | 0.00% | Shares |
| GAMMA Investing LLC | $8,487 | 462 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $6,233 | 338 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $5,750 | 313 | 0.00% | Shares |
| IFG Advisory, LLC | $4,997 | 272 | 0.00% | Shares |
| SIMPLEX TRADING, LLC | $4,959 | 270 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $4,886 | 266 | 0.00% | Shares |
| Arax Advisory Partners | $4,372 | 238 | 0.00% | Shares |
| Quarry LP | $4,225 | 230 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $4,097 | 223 | 0.00% | Shares |
| PNC Financial Services Group, Inc. | $4,078 | 222 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $3,814 | 208 | 0.00% | Shares |
| US BANCORP \DE\ | $3,490 | 190 | 0.00% | Shares |
| Versant Capital Management, Inc | $3,047 | 148 | 0.00% | Shares |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $2,772 | 150 | 0.00% | Shares |
| Smartleaf Asset Management LLC | $2,518 | 134 | 0.00% | Shares |
| Silver Grove Financial Group, Inc. | $2,131 | 116 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $2,021 | 110 | 0.00% | Shares |
| SG Americas Securities, LLC | $2,004 | 109,073 | 0.00% | Shares |
| Ameritas Advisory Services, LLC | $1,470 | 80 | 0.00% | Shares |
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ | $1,359 | 74 | 0.00% | Shares |
| Elequin Capital, LP | $1,304 | 71 | 0.00% | Shares |
| Parkside Financial Bank & Trust | $1,286 | 70 | 0.00% | Shares |
| Parallel Advisors, LLC | $1,194 | 65 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $903 | 49,177 | 0.00% | Shares |
| LRI Investments, LLC | $845 | 46 | 0.00% | Shares |
| Owl Creek Wealth Partners LLC | $827 | 45 | 0.00% | Shares |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $707 | 38,465 | 0.00% | Shares |
| Essential Partners LLC | $569 | 31 | 0.00% | Shares |
| Torren Management, LLC | $411 | 21 | 0.00% | Shares |
| Wealth Enhancement Trust Services, Inc. | $367 | 20 | 0.00% | Shares |
| SIGNATUREFD, LLC | $349 | 19 | 0.00% | Shares |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $252 | 13,692 | 0.00% | Shares |
| IFP Advisors, Inc | $184 | 10 | 0.00% | Shares |
| Pinnacle Wealth Planning Services, Inc. | $147 | 8 | 0.00% | Shares |
| KBC Group NV | $76 | 4,120 | 0.00% | Shares |
| Pacer Advisors, Inc. | $33 | 1,816 | 0.00% | Shares |
| BESSEMER GROUP INC | $7 | 355 | 0.00% | Shares |
| Covestor Ltd | $1 | 29 | 0.00% | Shares |